Alkbh3 (alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase) - Rat Genome Database

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Gene: Alkbh3 (alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase) Mus musculus
Analyze
Symbol: Alkbh3
Name: alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
RGD ID: 1550946
MGI Page MGI
Description: Enables broad specificity oxidative DNA demethylase activity; cytosine C-5 DNA demethylase activity; and oxidative RNA demethylase activity. Predicted to be involved in DNA alkylation repair; cell population proliferation; and negative regulation of cytoplasmic translation. Predicted to be located in cytosol. Predicted to be active in mitochondrion and nucleoplasm. Orthologous to human ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700108H04Rik; 1810020C19Rik; Abh; Abh3; alkB, alkylation repair homolog 3; alkylated DNA repair protein alkB homolog 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; mABH; mABH3; RP23-375N21.4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,810,979 - 93,841,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,810,895 - 93,841,152 (-)EnsemblGRCm39 Ensembl
GRCm38293,980,624 - 94,010,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,980,550 - 94,010,807 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,820,791 - 93,850,887 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,781,391 - 93,811,646 (-)NCBIMGSCv36mm8
Celera295,377,139 - 95,407,273 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
mitochondrion  (IBA,ISO)
nucleoplasm  (IBA,ISO)
nucleus  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16174769  
PMID:16642038   PMID:18519673   PMID:18799693   PMID:21267068   PMID:21873635   PMID:22429847   PMID:22684101   PMID:26930515   PMID:30541109   PMID:32325033   PMID:32554809   PMID:37198424  
PMID:38355793  


Genomics

Comparative Map Data
Alkbh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,810,979 - 93,841,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,810,895 - 93,841,152 (-)EnsemblGRCm39 Ensembl
GRCm38293,980,624 - 94,010,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,980,550 - 94,010,807 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,820,791 - 93,850,887 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,781,391 - 93,811,646 (-)NCBIMGSCv36mm8
Celera295,377,139 - 95,407,273 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.62NCBI
ALKBH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381143,880,831 - 43,920,274 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1143,880,811 - 43,920,274 (+)EnsemblGRCh38hg38GRCh38
GRCh371143,902,381 - 43,941,824 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361143,858,971 - 43,898,389 (+)NCBINCBI36Build 36hg18NCBI36
Celera1144,048,227 - 44,087,676 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1143,611,668 - 43,651,108 (+)NCBIHuRef
CHM1_11143,901,678 - 43,940,820 (+)NCBICHM1_1
T2T-CHM13v2.01144,036,210 - 44,075,625 (+)NCBIT2T-CHM13v2.0
Alkbh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83100,394,942 - 100,429,466 (-)NCBIGRCr8
mRatBN7.2379,939,515 - 79,972,820 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,939,600 - 79,972,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx383,413,118 - 83,445,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0392,012,208 - 92,044,463 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,857,713 - 89,889,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,874,242 - 82,907,467 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,874,248 - 82,906,581 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,575,451 - 89,608,158 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4378,386,098 - 78,418,432 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1378,282,525 - 78,314,860 (-)NCBI
Celera379,141,033 - 79,172,722 (-)NCBICelera
Cytogenetic Map3q31NCBI
Alkbh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554223,657,765 - 3,695,409 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554223,660,504 - 3,695,352 (-)NCBIChiLan1.0ChiLan1.0
ALKBH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,095,666 - 46,135,186 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,101,637 - 46,141,224 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01143,841,083 - 43,880,608 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,336,655 - 44,376,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,336,655 - 44,376,057 (+)Ensemblpanpan1.1panPan2
ALKBH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,864,041 - 25,899,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,824,877 - 25,899,079 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,551,100 - 25,585,936 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,486,584 - 26,521,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1826,449,542 - 26,519,594 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,996,121 - 26,030,947 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,641,660 - 25,676,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01826,253,706 - 26,288,540 (-)NCBIUU_Cfam_GSD_1.0
Alkbh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494722,615,131 - 22,666,079 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365624,741,371 - 4,777,727 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365624,743,595 - 4,777,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALKBH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl218,408,987 - 18,446,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1218,408,987 - 18,448,285 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2220,011,987 - 20,048,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALKBH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,463,744 - 21,505,940 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,462,516 - 21,505,934 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038118,701,961 - 118,743,776 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alkbh3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247674,103,446 - 4,139,345 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247674,088,173 - 4,139,288 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Alkbh3
1364 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1307
Count of miRNA genes:486
Interacting mature miRNAs:569
Transcripts:ENSMUST00000040005, ENSMUST00000111240, ENSMUST00000125473, ENSMUST00000126255, ENSMUST00000126378, ENSMUST00000127231, ENSMUST00000130289, ENSMUST00000130403, ENSMUST00000138046, ENSMUST00000138107, ENSMUST00000156763
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001418679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001418699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_026944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK007134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000040005   ⟹   ENSMUSP00000038721
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,810,982 - 93,841,075 (-)Ensembl
GRCm38.p6 Ensembl293,980,637 - 94,010,730 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111240   ⟹   ENSMUSP00000106871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,810,895 - 93,841,152 (-)Ensembl
GRCm38.p6 Ensembl293,980,550 - 94,010,807 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125473
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,810,895 - 93,815,165 (-)Ensembl
GRCm38.p6 Ensembl293,980,550 - 93,984,820 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,810,895 - 93,815,196 (-)Ensembl
GRCm38.p6 Ensembl293,980,550 - 93,984,851 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126378   ⟹   ENSMUSP00000122043
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,826,592 - 93,841,099 (-)Ensembl
GRCm38.p6 Ensembl293,996,247 - 94,010,754 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,826,592 - 93,835,532 (-)Ensembl
GRCm38.p6 Ensembl293,996,247 - 94,005,187 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130289
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,838,382 - 93,841,097 (-)Ensembl
GRCm38.p6 Ensembl294,008,037 - 94,010,752 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130403
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,810,974 - 93,811,971 (-)Ensembl
GRCm38.p6 Ensembl293,980,629 - 93,981,626 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,826,523 - 93,840,776 (-)Ensembl
GRCm38.p6 Ensembl293,996,178 - 94,010,431 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,836,119 - 93,841,099 (-)Ensembl
GRCm38.p6 Ensembl294,005,774 - 94,010,754 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156763
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl293,836,589 - 93,841,097 (-)Ensembl
GRCm38.p6 Ensembl294,006,244 - 94,010,752 (-)Ensembl
RefSeq Acc Id: NM_001418679   ⟹   NP_001405608
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418680   ⟹   NP_001405609
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418682   ⟹   NP_001405611
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418684   ⟹   NP_001405613
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418685   ⟹   NP_001405614
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418687   ⟹   NP_001405616
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418689   ⟹   NP_001405618
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418690   ⟹   NP_001405619
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418692   ⟹   NP_001405621
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418694   ⟹   NP_001405623
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418696   ⟹   NP_001405625
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,824,236 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418698   ⟹   NP_001405627
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_001418699   ⟹   NP_001405628
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NM_026944   ⟹   NP_081220
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
GRCm38293,980,634 - 94,010,730 (-)NCBI
MGSCv37293,820,791 - 93,850,887 (-)RGD
Celera295,377,139 - 95,407,273 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_184795
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NR_184796
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NR_184797
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NR_184798
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NR_184799
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NR_184800
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39293,810,979 - 93,841,099 (-)NCBI
RefSeq Acc Id: NP_081220   ⟸   NM_026944
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000106871   ⟸   ENSMUST00000111240
Ensembl Acc Id: ENSMUSP00000038721   ⟸   ENSMUST00000040005
Ensembl Acc Id: ENSMUSP00000122043   ⟸   ENSMUST00000126378
RefSeq Acc Id: NP_001405611   ⟸   NM_001418682
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405623   ⟸   NM_001418694
- Peptide Label: isoform d
RefSeq Acc Id: NP_001405616   ⟸   NM_001418687
- Peptide Label: isoform b
- UniProtKB: A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405621   ⟸   NM_001418692
- Peptide Label: isoform c
RefSeq Acc Id: NP_001405627   ⟸   NM_001418698
- Peptide Label: isoform f
RefSeq Acc Id: NP_001405609   ⟸   NM_001418680
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405618   ⟸   NM_001418689
- Peptide Label: isoform b
- UniProtKB: A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405619   ⟸   NM_001418690
- Peptide Label: isoform c
RefSeq Acc Id: NP_001405628   ⟸   NM_001418699
- Peptide Label: isoform f
RefSeq Acc Id: NP_001405608   ⟸   NM_001418679
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405613   ⟸   NM_001418684
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405614   ⟸   NM_001418685
- Peptide Label: isoform a
- UniProtKB: Q8K1E6 (UniProtKB/Swiss-Prot),   A2AKV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001405625   ⟸   NM_001418696
- Peptide Label: isoform e
- UniProtKB: A2AKV7 (UniProtKB/TrEMBL)
Protein Domains
Alpha-ketoglutarate-dependent dioxygenase AlkB-like   Fe2OG dioxygenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K1E6-F1-model_v2 AlphaFold Q8K1E6 1-286 view protein structure

Promoters
RGD ID:6830782
Promoter ID:MM_KWN:30670
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000111240,   NM_026944,   OTTMUST00000035626,   OTTMUST00000035627,   OTTMUST00000035628,   OTTMUST00000035629,   OTTMUST00000035630,   UC008LGO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36293,850,674 - 93,851,174 (-)MPROMDB
RGD ID:6878008
Promoter ID:EPDNEW_M2454
Type:initiation region
Name:Alkbh3_2
Description:Mus musculus alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2455  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38293,984,834 - 93,984,894EPDNEW
RGD ID:6878062
Promoter ID:EPDNEW_M2455
Type:multiple initiation site
Name:Alkbh3_1
Description:Mus musculus alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2454  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38294,010,754 - 94,010,814EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916363 AgrOrtholog
Ensembl Genes ENSMUSG00000040174 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000040005 ENTREZGENE
  ENSMUST00000040005.13 UniProtKB/Swiss-Prot
  ENSMUST00000111240.8 UniProtKB/TrEMBL
  ENSMUST00000126378 ENTREZGENE
  ENSMUST00000126378.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.590 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AlkB-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AlkB-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALKBH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Oxoglu/Fe-dep_dioxygenase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69113 UniProtKB/Swiss-Prot
MGD MGI:1916363 ENTREZGENE
NCBI Gene 69113 ENTREZGENE
PANTHER ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR31212 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Alkbh3 PhenoGen
PROSITE FE2OG_OXY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Clavaminate synthase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AKV6 ENTREZGENE, UniProtKB/TrEMBL
  A2AKV7 ENTREZGENE, UniProtKB/TrEMBL
  ALKB3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 Alkbh3  alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase    alkB, alkylation repair homolog 3 (E. coli)  Symbol and/or name change 5135510 APPROVED