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Gene: Vapb (vesicle-associated membrane protein, associated protein B and C) Mus musculus
Symbol: Vapb
Name: vesicle-associated membrane protein, associated protein B and C
Description: Predicted to have several functions, including FFAT motif binding activity; protein dimerization activity; and tubulin binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; endoplasmic reticulum organization; and modulation by host of viral process. Localizes to membrane. Is expressed in dorsal root ganglion. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPB (VAMP associated protein B and C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI225786; AI840687; AI848259; D2Abb2e; R75548; VAMP-associated protein 33b; VAMP-associated protein B; VAMP-B; Vamp33b; VAP-B; VAP33b; vesicle-associated membrane protein-associated protein B
Homo sapiens (human) : VAPB (VAMP associated protein B and C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vapb (VAMP associated protein B and C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vapb (VAMP associated protein B and C)
Pan paniscus (bonobo/pygmy chimpanzee) : VAPB (VAMP associated protein B and C)
Canis lupus familiaris (dog) : VAPB (VAMP associated protein B and C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vapb (VAMP associated protein B and C)
Sus scrofa (pig) : VAPB (VAMP associated protein B and C)
Chlorocebus sabaeus (African green monkey) : VAPB (VAMP associated protein B and C)
Heterocephalus glaber (naked mole-rat) : Vapb (VAMP associated protein B and C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2173,737,511 - 173,784,339 (+)EnsemblGRCm38mm10GRCm38
GRCm382173,737,571 - 173,784,336 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372173,563,072 - 173,609,837 (+)NCBIGRCm37mm9NCBIm37
MGSCv362173,380,510 - 173,427,275 (+)NCBImm8
Celera2179,705,544 - 179,751,066 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map297.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Vapb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68453
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.