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Gene: Ptbp1 (polypyrimidine tract binding protein 1) Mus musculus
Symbol: Ptbp1
Name: polypyrimidine tract binding protein 1
Description: Exhibits RNA binding activity. Involved in gene expression; negative regulation of neuron differentiation; and regulation of RNA metabolic process. Localizes to nucleus. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; sensory organ; and tooth. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA407203; AL033359; heterogeneous nuclear ribonucleoprotein I; hnRNP I; HNRPI; polypyrimidine tract-binding protein 1; pPTB; Ptb; PTB-1; PTB2; PTB3; PTB4
Homo sapiens (human) : PTBP1 (polypyrimidine tract binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptbp1 (polypyrimidine tract binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptbp1 (polypyrimidine tract binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTBP1 (polypyrimidine tract binding protein 1)
Canis lupus familiaris (dog) : PTBP1 (polypyrimidine tract binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptbp1 (polypyrimidine tract binding protein 1)
Sus scrofa (pig) : PTBP1 (polypyrimidine tract binding protein 1)
Chlorocebus sabaeus (African green monkey) : PTBP1 (polypyrimidine tract binding protein 1)
Heterocephalus glaber (naked mole-rat) : Ptbp1 (polypyrimidine tract binding protein 1)
more info ...
Related Pseudogenes: Gm14451   Gm14452   Gm18773   Gm18815   Gm2639   Gm4900   Gm8424  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1079,854,427 - 79,864,771 (+)EnsemblGRCm38mm10GRCm38
GRCm381079,854,432 - 79,864,435 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371079,317,350 - 79,327,178 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,257,809 - 79,267,900 (+)NCBImm8
Celera1080,869,418 - 80,879,246 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptbp1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62339
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.