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Gene: C6 (complement component 6) Mus musculus
Symbol: C6
Name: complement component 6
Description: Involved in in utero embryonic development; positive regulation of activation of membrane attack complex; and positive regulation of angiogenesis. Predicted to localize to the extracellular space and membrane attack complex. Human ortholog(s) of this gene implicated in complement component 6 deficiency. Is expressed in embryo. Orthologous to human C6 (complement C6); PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW111623; complement component C6
Homo sapiens (human) : C6 (complement C6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : C6 (complement C6)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : C6 (complement C6)
Canis lupus familiaris (dog) : C6 (complement C6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C6 (complement C6)
Sus scrofa (pig) : C6 (complement C6)
Chlorocebus sabaeus (green monkey) : C6 (complement C6)
Heterocephalus glaber (naked mole-rat) : C6 (complement C6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl154,727,175 - 4,814,967 (+)Ensembl
GRCm38154,727,067 - 4,804,045 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37154,677,210 - 4,754,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv36154,677,212 - 4,754,044 (+)NCBImm8
Celera154,580,241 - 4,656,631 (+)NCBICelera
Cytogenetic Map15 A1NCBI
cM Map151.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on C6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552917
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.