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Gene: C6 (complement component 6) Mus musculus
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Symbol: C6
Name: complement component 6
Description: Involved in in utero embryonic development; positive regulation of activation of membrane attack complex; and positive regulation of angiogenesis. Predicted to localize to the extracellular space and membrane attack complex. Human ortholog(s) of this gene implicated in complement component 6 deficiency. Is expressed in embryo. Orthologous to human C6 (complement C6); PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW111623; complement component C6
Orthologs:
Homo sapiens (human) : C6 (complement C6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : C6 (complement C6)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : C6 (complement C6)
Canis lupus familiaris (dog) : C6 (complement C6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C6 (complement C6)
Sus scrofa (pig) : C6 (complement C6)
Chlorocebus sabaeus (green monkey) : C6 (complement C6)
Heterocephalus glaber (naked mole-rat) : C6 (complement C6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl154,727,175 - 4,814,967 (+)Ensembl
GRCm38154,727,067 - 4,804,045 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37154,677,210 - 4,754,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv36154,677,212 - 4,754,044 (+)NCBImm8
Celera154,580,241 - 4,656,631 (+)NCBICelera
Cytogenetic Map15 A1NCBI
cM Map151.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on C6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552917
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.