Pabpc1 (poly(A) binding protein, cytoplasmic 1) - Rat Genome Database

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Gene: Pabpc1 (poly(A) binding protein, cytoplasmic 1) Mus musculus
Analyze
Symbol: Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
RGD ID: 1552448
MGI Page MGI
Description: Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; and regulatory ncRNA-mediated gene silencing. Located in cytoplasm. Is active in synapse. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ePAB; Pa; PABP; PABP-1; Pabp1; PabpI; Pabpl1; poly A binding protein 1; poly(A)-binding protein 1; polyadenylate-binding protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm16580   Gm18790   Gm18793   Gm8276  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391536,595,902 - 36,609,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1536,595,905 - 36,609,912 (-)EnsemblGRCm39 Ensembl
GRCm381536,595,658 - 36,609,581 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1536,595,661 - 36,609,668 (-)EnsemblGRCm38mm10GRCm38
MGSCv371536,525,413 - 36,538,728 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361536,540,252 - 36,553,551 (-)NCBIMGSCv36mm8
Celera1537,216,852 - 37,230,173 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-vinylcyclohexene dioxide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
aconitine  (ISO)
acrolein  (ISO)
alpha-pinene  (ISO)
amino acid  (EXP,ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chlormequat chloride  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
clofibric acid  (ISO)
cocaine  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
etoposide  (EXP)
flavonoids  (ISO)
folic acid  (EXP)
gentamycin  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
isoflavones  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
menadione  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methoxychlor  (EXP)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rotenone  (ISO)
senecionine  (EXP)
silicon dioxide  (EXP)
sirolimus  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
torin 1  (ISO)
triadimefon  (ISO)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The mechanism of eukaryotic translation initiation: new insights and challenges. Hinnebusch AG and Lorsch JR, Cold Spring Harb Perspect Biol. 2012 Oct 1;4(10). pii: a011544. doi: 10.1101/cshperspect.a011544.
2. The scanning mechanism of eukaryotic translation initiation. Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:1630930   PMID:1701491   PMID:7893484   PMID:9883581   PMID:10076007   PMID:10349636   PMID:10534404   PMID:11042159   PMID:11076861   PMID:11322760   PMID:11389549   PMID:12477932  
PMID:12520002   PMID:12904583   PMID:14610273   PMID:15314026   PMID:15630085   PMID:15782199   PMID:16033648   PMID:16107646   PMID:16141072   PMID:16141073   PMID:16452087   PMID:16798735  
PMID:16804161   PMID:17218272   PMID:17927953   PMID:17967808   PMID:18495661   PMID:18625844   PMID:18799693   PMID:18973680   PMID:19020299   PMID:19328788   PMID:19345177   PMID:19716330  
PMID:20975687   PMID:21262862   PMID:21589869   PMID:21677750   PMID:21873635   PMID:21940797   PMID:21984414   PMID:22621333   PMID:22794259   PMID:22814100   PMID:22956915   PMID:23230274  
PMID:24129315   PMID:24396066   PMID:24457600   PMID:24599567   PMID:24648398   PMID:25034140   PMID:25157170   PMID:25370180   PMID:26134869   PMID:26265008   PMID:26336360   PMID:26426291  
PMID:26492470   PMID:26496610   PMID:26590968   PMID:26627310   PMID:27160897   PMID:27746211   PMID:28203794   PMID:28252024   PMID:28378742   PMID:28611064   PMID:28635594   PMID:28653618  
PMID:28671696   PMID:28756945   PMID:28910620   PMID:29578408   PMID:29590218   PMID:29676259   PMID:29701755   PMID:30196744   PMID:30302808   PMID:30333137   PMID:30409884   PMID:30550785  
PMID:30713523   PMID:31138677   PMID:31847264   PMID:32248978   PMID:32325033   PMID:32434143   PMID:32554809   PMID:32581705   PMID:32968282   PMID:33601422   PMID:34133714   PMID:34784943  
PMID:35511136   PMID:36001654   PMID:36114006   PMID:36293380   PMID:37704377  


Genomics

Comparative Map Data
Pabpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391536,595,902 - 36,609,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1536,595,905 - 36,609,912 (-)EnsemblGRCm39 Ensembl
GRCm381536,595,658 - 36,609,581 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1536,595,661 - 36,609,668 (-)EnsemblGRCm38mm10GRCm38
MGSCv371536,525,413 - 36,538,728 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361536,540,252 - 36,553,551 (-)NCBIMGSCv36mm8
Celera1537,216,852 - 37,230,173 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.51NCBI
PABPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388100,702,916 - 100,722,088 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8100,685,816 - 100,722,809 (-)EnsemblGRCh38hg38GRCh38
GRCh378101,715,144 - 101,734,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368101,784,320 - 101,803,491 (-)NCBINCBI36Build 36hg18NCBI36
Build 348101,784,319 - 101,803,491NCBI
Celera897,900,528 - 97,919,706 (-)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef896,913,861 - 96,933,038 (-)NCBIHuRef
CHM1_18101,755,929 - 101,775,103 (-)NCBICHM1_1
T2T-CHM13v2.08101,828,977 - 101,848,145 (-)NCBIT2T-CHM13v2.0
Pabpc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8769,662,513 - 69,674,806 (-)NCBIGRCr8
mRatBN7.2767,777,438 - 67,789,731 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl767,777,381 - 67,789,744 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx769,665,830 - 69,678,123 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0771,868,434 - 71,880,727 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0771,736,315 - 71,748,608 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0775,409,581 - 75,421,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl775,409,581 - 75,422,268 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0775,557,634 - 75,569,927 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,116,140 - 72,128,433 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1772,136,510 - 72,149,407 (-)NCBI
Celera764,857,404 - 64,869,695 (-)NCBICelera
Cytogenetic Map7q22NCBI
Pabpc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541715,868,934 - 15,885,247 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541715,872,906 - 15,885,246 (-)NCBIChiLan1.0ChiLan1.0
PABPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27118,056,637 - 118,076,633 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1893,592,669 - 93,612,674 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0897,346,433 - 97,365,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1899,518,347 - 99,534,284 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl899,518,347 - 99,537,614 (-)Ensemblpanpan1.1panPan2
PABPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1132,563,698 - 2,580,610 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl132,564,065 - 2,580,368 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,560,662 - 2,577,627 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0132,717,070 - 2,734,072 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl132,687,294 - 2,837,742 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1132,561,235 - 2,578,211 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0132,672,912 - 2,689,894 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0132,690,335 - 2,707,304 (-)NCBIUU_Cfam_GSD_1.0
Pabpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530335,202,647 - 35,244,212 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647042,628,667 - 42,643,347 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647042,628,890 - 42,670,311 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PABPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl436,209,164 - 36,228,073 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1436,137,644 - 36,228,075 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2439,133,409 - 39,152,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PABPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1895,560,551 - 95,578,627 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl895,561,930 - 95,578,633 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603945,104,972 - 45,123,828 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pabpc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247637,550,307 - 7,567,918 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247637,552,541 - 7,568,047 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pabpc1
333 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:380
Interacting mature miRNAs:438
Transcripts:ENSMUST00000001809, ENSMUST00000142357, ENSMUST00000146327, ENSMUST00000146577, ENSMUST00000147116, ENSMUST00000155116, ENSMUST00000156793
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141358Ath22_matherosclerosis 22 (mouse)Not determined346465237464652Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562049439620614Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15612948138000244Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15812948438763395Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927302243311880Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927302243311880Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384700647847148Mouse
1302165Yv_myellow value (mouse)Not determined151384700647847148Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492758748927756Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492758748927756Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492758748927756Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564534349645470Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603395450033954Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060008650763396Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1301760Dob9_mdietary obesity 9 (mouse)Body fat amountadiposity index152603568037781301Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
12904003Opfaq12_mopen field activity QTL 12 (mouse)153435891138447901Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse

Markers in Region
D13S1095E  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,270,214 - 26,270,335UniSTSGRCm38
MGSCv371726,407,159 - 26,407,280UniSTSGRCm37
Celera1726,805,077 - 26,805,198UniSTS
Cytogenetic Map15CUniSTS
Cytogenetic Map17B1UniSTS
cM Map1711.8UniSTS
Pabpc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,269,562 - 26,270,273UniSTSGRCm38
MGSCv371726,406,507 - 26,407,218UniSTSGRCm37
Celera1726,804,409 - 26,805,136UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map15CUniSTS
cM MapUN UniSTS
cM Map18 UniSTS
cM Map15 UniSTS
cM Map1711.8UniSTS
Pabpc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,269,772 - 26,270,360UniSTSGRCm38
GRCm38359,432,740 - 59,433,324UniSTSGRCm38
MGSCv371726,406,717 - 26,407,305UniSTSGRCm37
MGSCv37359,236,662 - 59,237,246UniSTSGRCm37
Celera359,118,462 - 59,119,046UniSTS
Celera1726,804,619 - 26,805,223UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map15CUniSTS
Pabpc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381536,599,309 - 36,601,007UniSTSGRCm38
GRCm38359,432,190 - 59,432,593UniSTSGRCm38
MGSCv371536,529,064 - 36,530,762UniSTSGRCm37
MGSCv37359,236,112 - 59,236,515UniSTSGRCm37
Celera359,117,912 - 59,118,315UniSTS
Celera1537,220,503 - 37,222,201UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15CUniSTS
Pabpc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381839,774,217 - 39,775,342UniSTSGRCm38
GRCm38359,431,986 - 59,433,129UniSTSGRCm38
MGSCv371839,933,871 - 39,934,996UniSTSGRCm37
MGSCv37359,235,908 - 59,237,051UniSTSGRCm37
Celera1841,126,101 - 41,127,226UniSTS
Celera359,117,708 - 59,118,851UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15CUniSTS
cM Map15 UniSTS
cM Map18 UniSTS
cM MapUN UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC137871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ279847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF553208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000001809   ⟹   ENSMUSP00000001809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,595,905 - 36,609,217 (-)Ensembl
GRCm38.p6 Ensembl1536,595,661 - 36,608,973 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,596,268 - 36,597,670 (-)Ensembl
GRCm38.p6 Ensembl1536,596,024 - 36,597,426 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,603,740 - 36,609,217 (-)Ensembl
GRCm38.p6 Ensembl1536,603,496 - 36,608,973 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146577
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,596,268 - 36,598,556 (-)Ensembl
GRCm38.p6 Ensembl1536,596,024 - 36,598,312 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147116
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,596,445 - 36,597,980 (-)Ensembl
GRCm38.p6 Ensembl1536,596,201 - 36,597,736 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155116   ⟹   ENSMUSP00000117063
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,596,151 - 36,598,263 (-)Ensembl
GRCm38.p6 Ensembl1536,595,907 - 36,598,019 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156793
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,598,545 - 36,602,590 (-)Ensembl
GRCm38.p6 Ensembl1536,598,301 - 36,602,346 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226496   ⟹   ENSMUSP00000154430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,605,996 - 36,609,912 (-)Ensembl
GRCm38.p6 Ensembl1536,605,752 - 36,609,668 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,599,197 - 36,600,006 (-)Ensembl
GRCm38.p6 Ensembl1536,598,953 - 36,599,762 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226867
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1536,600,665 - 36,605,710 (-)Ensembl
GRCm38.p6 Ensembl1536,600,421 - 36,605,466 (-)Ensembl
RefSeq Acc Id: NM_008774   ⟹   NP_032800
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391536,595,902 - 36,609,217 (-)NCBI
GRCm381536,595,658 - 36,608,973 (-)NCBI
MGSCv371536,525,413 - 36,538,728 (-)RGD
Celera1537,216,852 - 37,230,173 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011245339   ⟹   XP_011243641
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391536,595,904 - 36,609,825 (-)NCBI
GRCm381536,595,665 - 36,609,581 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_032800   ⟸   NM_008774
- UniProtKB: Q99L36 (UniProtKB/Swiss-Prot),   P29341 (UniProtKB/Swiss-Prot),   Q3U8U8 (UniProtKB/TrEMBL),   Q8BN32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243641   ⟸   XM_011245339
- Peptide Label: isoform X1
- UniProtKB: Q99L36 (UniProtKB/Swiss-Prot),   P29341 (UniProtKB/Swiss-Prot),   Q3U8U8 (UniProtKB/TrEMBL),   Q8BN32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000154430   ⟸   ENSMUST00000226496
RefSeq Acc Id: ENSMUSP00000001809   ⟸   ENSMUST00000001809
RefSeq Acc Id: ENSMUSP00000117063   ⟸   ENSMUST00000155116
Protein Domains
PABC   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P29341-F1-model_v2 AlphaFold P29341 1-636 view protein structure

Promoters
RGD ID:6826300
Promoter ID:MM_KWN:18269
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   MEF_B6
Transcripts:OTTMUST00000047298,   OTTMUST00000047299,   OTTMUST00000047300,   OTTMUST00000047302
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361536,527,031 - 36,528,942 (-)MPROMDB
RGD ID:6826301
Promoter ID:MM_KWN:18270
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_2Hour,   Liver,   MEF_B6
Transcripts:OTTMUST00000047301
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361536,531,801 - 36,532,352 (-)MPROMDB
RGD ID:6847229
Promoter ID:MM_ACW:17807
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   MEF_B6
Transcripts:PABPC1.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361536,535,224 - 36,535,724 (-)MPROMDB
RGD ID:6826299
Promoter ID:MM_KWN:18271
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_008774,   OTTMUST00000047297
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361536,538,151 - 36,539,452 (-)MPROMDB
RGD ID:8683598
Promoter ID:EPDNEW_M19830
Type:multiple initiation site
Name:Pabpc1_1
Description:Mus musculus poly binding protein, cytoplasmic 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381536,608,972 - 36,609,032EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349722 AgrOrtholog
Ensembl Genes ENSMUSG00000022283 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001809 ENTREZGENE
  ENSMUST00000001809.15 UniProtKB/Swiss-Prot
  ENSMUST00000155116.2 UniProtKB/TrEMBL
  ENSMUST00000226496.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  c-terminal domain of poly(a) binding protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABP-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABP_1234 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABP_HYD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABP_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM2_I_PABPs UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18458 UniProtKB/Swiss-Prot
MGD MGI:1349722 ENTREZGENE
NCBI Gene 18458 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR5 UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE UBR5 UniProtKB/TrEMBL
  POLYADENYLATE-BINDING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PABP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pabpc1 PhenoGen
PROSITE PABC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PolyA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63570 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BR37_MOUSE UniProtKB/TrEMBL
  F6ZAX1_MOUSE UniProtKB/TrEMBL
  P29341 ENTREZGENE, UniProtKB/Swiss-Prot
  Q05DT1_MOUSE UniProtKB/TrEMBL
  Q3U8U8 ENTREZGENE, UniProtKB/TrEMBL
  Q8BN32 ENTREZGENE, UniProtKB/TrEMBL
  Q99KL3_MOUSE UniProtKB/TrEMBL
  Q99L36 ENTREZGENE
  Q9DBE3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q99L36 UniProtKB/Swiss-Prot