Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SF3A1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SF3A1 mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SF3A1 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SF3A1 promoter] | CTD | PMID:17942748 and PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SF3A1 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of SF3A1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SF3A1 mRNA | CTD | PMID:21346803 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SF3A1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of SF3A1 protein | CTD | PMID:34186270 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of SF3A1 mRNA | CTD | PMID:21346803 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of SF3A1 mRNA | CTD | PMID:28973697 | aconitine | increases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | Aconitine results in increased expression of SF3A1 protein | CTD | PMID:33236894 | aflatoxin B1 | increases methylation | ISO | SF3A1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SF3A1 gene | CTD | PMID:27153756 | atrazine | decreases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SF3A1 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | affects methylation | ISO | SF3A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SF3A1 3' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SF3A1 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SF3A1 mRNA | CTD | PMID:34947998 | Brodifacoum | decreases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of SF3A1 protein | CTD | PMID:28903499 | butanal | decreases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SF3A1 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SF3A1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SF3A1 mRNA | CTD | PMID:35301059 | caffeine | increases phosphorylation | ISO | SF3A1 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of SF3A1 protein | CTD | PMID:35688186 | cannabidiol | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of SF3A1 protein | CTD | PMID:34122009 | cisplatin | decreases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of SF3A1 mRNA | CTD | PMID:27594783 | coumarin | increases phosphorylation | ISO | SF3A1 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of SF3A1 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SF3A1 mRNA | CTD | PMID:25562108 | cyclosporin A | increases methylation | ISO | SF3A1 (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of SF3A1 promoter | CTD | PMID:27989131 | deoxynivalenol | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of SF3A1 mRNA | CTD | PMID:31863870 | diazinon | increases methylation | ISO | SF3A1 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of SF3A1 gene | CTD | PMID:22964155 | dicrotophos | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of SF3A1 mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SF3A1 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SF3A1 mRNA | CTD | PMID:27188386 | enzyme inhibitor | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SF3A1 protein | CTD | PMID:23301498 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of SF3A1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of SF3A1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SF3A1 mRNA | CTD | PMID:22206623 | FR900359 | increases phosphorylation | ISO | SF3A1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SF3A1 protein | CTD | PMID:37730182 | glyphosate | increases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | Glyphosate results in increased expression of SF3A1 mRNA | CTD | PMID:26302742 | hydrogen peroxide | multiple interactions | EXP | | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5 more ... | CTD | PMID:31494107 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SF3A1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SF3A1 protein | CTD | PMID:32959892 | methylmercury chloride | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of SF3A1 mRNA | CTD | PMID:23179753 and PMID:26272509 | methylmercury chloride | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SF3A1 mRNA | CTD | PMID:27188386 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of SF3A1 protein | CTD | PMID:26558463 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SF3A1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SF3A1 mRNA | CTD | PMID:22230336 | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of SF3A1 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SF3A1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of SF3A1 mRNA | CTD | PMID:36331819 | progesterone | increases expression | EXP | | 6480464 | Progesterone results in increased expression of SF3A1 mRNA | CTD | PMID:19693291 | resveratrol | decreases expression | EXP | | 6480464 | resveratrol results in decreased expression of SF3A1 protein | CTD | PMID:25505154 | resveratrol | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SF3A1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | SF3A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SF3A1 mRNA | CTD | PMID:27188386 | testosterone | increases expression | EXP | | 6480464 | Testosterone results in increased expression of SF3A1 mRNA | CTD | PMID:19693291 | thioacetamide | increases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of SF3A1 mRNA | CTD | PMID:34492290 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of SF3A1 mRNA | CTD | PMID:19042947 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of SF3A1 mRNA | CTD | PMID:33045310 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of SF3A1 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | EXP | | 6480464 | Tunicamycin results in increased expression of SF3A1 mRNA | CTD | PMID:17127020 | valproic acid | affects expression | ISO | SF3A1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SF3A1 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | ISO | Sf3a1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of SF3A1 mRNA | CTD | PMID:23034163 | Yessotoxin | decreases expression | ISO | SF3A1 (Homo sapiens) | 6480464 | yessotoxin analog results in decreased expression of SF3A1 mRNA | CTD | PMID:30679557 | |