Hdac2 (histone deacetylase 2) - Rat Genome Database
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Gene: Hdac2 (histone deacetylase 2) Mus musculus
Symbol: Hdac2
Name: histone deacetylase 2
RGD ID: 1312510
Description: Exhibits several functions, including DNA binding activity; Krueppel-associated box domain binding activity; and RNA polymerase II transcription corepressor binding activity. Involved in several processes, including animal organ development; histone modification; and regulation of cell development. Localizes to RNA polymerase II transcription repressor complex and chromosome. Is expressed in several structures, including brain; early conceptus; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human HDAC2 (histone deacetylase 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; Hedgehog signaling pathway; histone modification pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D10Wsu179; D10Wsu179e; HD2; mRPD3; YAF1; YY1 transcription factor-binding protein; Yy1b; Yy1bp
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8022  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391036,850,293 - 36,877,885 (+)NCBIGRCm39mm39
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1019.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(20S)-ginsenoside Rh2  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3',5'-cyclic AMP  (ISO)
3,3'-diindolylmethane  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (EXP)
ammonium chloride  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
capsaicin  (ISO)
choline  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (ISO)
glafenine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
isoprenaline  (EXP,ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
manganese(II) chloride  (ISO)
mechlorethamine  (ISO)
menadione  (ISO)
methoxyacetic acid  (ISO)
mifepristone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nefazodone  (ISO)
nickel subsulfide  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
oxybenzone  (ISO)
pelargonidin  (EXP)
perfluorooctanoic acid  (ISO)
Plantamajoside  (EXP,ISO)
resveratrol  (ISO)
romidepsin  (ISO)
rotenone  (ISO)
sevoflurane  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
tamoxifen  (EXP,ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
valsartan  (EXP,ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
behavioral response to ethanol  (ISO)
cardiac muscle cell development  (IMP)
cardiac muscle hypertrophy  (ISO)
cellular response to dopamine  (ISO)
cellular response to heat  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to trichostatin A  (IDA)
chromatin organization  (TAS)
circadian regulation of gene expression  (IDA)
dendrite development  (IMP)
embryonic digit morphogenesis  (IGI)
epidermal cell differentiation  (IGI)
eyelid development in camera-type eye  (IGI)
fungiform papilla formation  (IGI)
hair follicle placode formation  (IGI)
heterochromatin maintenance  (ISO)
hippocampus development  (IGI)
histone deacetylation  (IGI,ISO)
histone H3 deacetylation  (IBA,IDA,ISO)
histone H3-K27 methylation  (IMP)
histone H4 deacetylation  (IBA,IDA)
negative regulation of apoptotic process  (IGI)
negative regulation of canonical Wnt signaling pathway  (IGI)
negative regulation of cardiac muscle cell proliferation  (IMP)
negative regulation of dendritic spine development  (ISO)
negative regulation of DNA binding  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (IGI)
negative regulation of neuron projection development  (IDA,ISO)
negative regulation of peptidyl-lysine acetylation  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (IGI,IMP)
negative regulation of transcription by RNA polymerase II  (IGI,ISO)
negative regulation of transcription, DNA-templated  (IDA,ISO)
neuron differentiation  (IGI)
odontogenesis of dentin-containing tooth  (IGI)
positive regulation of cell population proliferation  (IGI,ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of interleukin-1 production  (ISO)
positive regulation of male mating behavior  (ISO)
positive regulation of oligodendrocyte differentiation  (IGI,ISO)
positive regulation of proteolysis  (ISO)
positive regulation of signaling receptor activity  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
protein deacetylation  (IDA)
regulation of protein deacetylation  (IGI)
regulation of protein kinase B signaling  (IMP)
regulation of sarcomere organization  (IMP)
response to amphetamine  (ISO)
response to caffeine  (ISO)
response to cocaine  (ISO)
response to drug  (ISO)
response to hyperoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to nicotine  (ISO)
rhythmic process  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiovascular system morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell physiology  (IAGP)
abnormal coat appearance  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart right ventricle morphology  (IAGP)
abnormal hippocampus CA1 region morphology  (IAGP)
abnormal hippocampus pyramidal cell morphology  (IAGP)
abnormal intestinal mucosa morphology  (IAGP)
abnormal large intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal mitosis  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal nail color  (IAGP)
abnormal nail morphology  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal thymus corticomedullary boundary morphology  (IAGP)
abnormal total retina thickness  (IAGP)
abnormal vibrissa morphology  (IAGP)
anemia  (IAGP)
aneuploidy  (IAGP)
arrested B cell differentiation  (IAGP)
arrested T cell differentiation  (IAGP)
cardiac hypertrophy  (IAGP)
chromosomal instability  (IAGP)
cyanosis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased birth body size  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased brain weight  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased heart rate  (IAGP)
decreased intestine length  (IAGP)
decreased megakaryocyte cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased survivor rate  (IAGP)
decreased susceptilbility to retinal ischemic injury  (IAGP)
decreased thymocyte number  (IAGP)
decreased tumor incidence  (IAGP)
diffuse Z line  (IAGP)
dilated heart ventricle  (IAGP)
distended abdomen  (IAGP)
early cellular replicative senescence  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced contextual conditioning behavior  (IAGP)
enhanced long term potentiation  (IAGP)
enlarged chest  (IAGP)
enlarged heart  (IAGP)
enlarged spleen  (IAGP)
enlarged thymus  (IAGP)
hyperkeratosis  (IAGP)
increased apoptosis  (IAGP)
increased B cell apoptosis  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased fibroblast apoptosis  (IAGP)
increased foot pad pigmentation  (IAGP)
increased pulmonary respiratory rate  (IAGP)
increased single-positive T cell number  (IAGP)
increased small intestine adenocarcinoma incidence  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased T cell proliferation  (IAGP)
increased thymocyte apoptosis  (IAGP)
increased thymocyte number  (IAGP)
increased tumor incidence  (IAGP)
insensitivity to growth hormone  (IAGP)
internal hemorrhage  (IAGP)
irregular heartbeat  (IAGP)
lethargy  (IAGP)
narrow eye opening  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
reduced fertility  (IAGP)
short vibrissae  (IAGP)
small testis  (IAGP)
small vertebrae  (IAGP)
thick interventricular septum  (IAGP)
thick ventricular wall  (IAGP)
thrombocytopenia  (IAGP)
thymus hypoplasia  (IAGP)
trisomy  (IAGP)

References - curated
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Additional References at PubMed
PMID:8917507   PMID:9702189   PMID:9786895   PMID:9874765   PMID:10204490   PMID:10349636   PMID:10431247   PMID:10508171   PMID:10725249   PMID:10888872   PMID:10984530   PMID:11042159  
PMID:11076861   PMID:11101889   PMID:11217851   PMID:11327722   PMID:11358320   PMID:11788710   PMID:11836251   PMID:11923873   PMID:12007404   PMID:12082111   PMID:12398767   PMID:12477932  
PMID:12520002   PMID:12711221   PMID:12904583   PMID:12930754   PMID:12975471   PMID:14519686   PMID:14610273   PMID:14643676   PMID:14673164   PMID:15060137   PMID:15073182   PMID:15120635  
PMID:15199142   PMID:15226430   PMID:15226823   PMID:15367668   PMID:15456770   PMID:15496408   PMID:15522123   PMID:15537544   PMID:15601857   PMID:15696166   PMID:15703188   PMID:15920471  
PMID:16107708   PMID:16109738   PMID:16141072   PMID:16141073   PMID:16260608   PMID:16288735   PMID:16407282   PMID:16510470   PMID:16602821   PMID:16873063   PMID:16923961   PMID:17093407  
PMID:17182846   PMID:17220375   PMID:17255939   PMID:17296600   PMID:17322895   PMID:17392792   PMID:17639084   PMID:17666527   PMID:17707228   PMID:17909008   PMID:18241125   PMID:18287559  
PMID:18454139   PMID:18458156   PMID:18495085   PMID:18501342   PMID:18508077   PMID:18651664   PMID:18754010   PMID:18824292   PMID:18983969   PMID:19015268   PMID:19041327   PMID:19047631  
PMID:19124609   PMID:19139101   PMID:19362090   PMID:19380719   PMID:19412887   PMID:19416910   PMID:19424149   PMID:19463978   PMID:19494835   PMID:19503085   PMID:19553468   PMID:19605684  
PMID:19654328   PMID:19759294   PMID:19906951   PMID:19935709   PMID:20073046   PMID:20097764   PMID:20185820   PMID:20188178   PMID:20194438   PMID:20211142   PMID:20362541   PMID:20404188  
PMID:20571512   PMID:20596014   PMID:20720167   PMID:20823130   PMID:20833366   PMID:20972425   PMID:20979029   PMID:21093383   PMID:21094147   PMID:21103394   PMID:21177534   PMID:21258411  
PMID:21270520   PMID:21270677   PMID:21292776   PMID:21364650   PMID:21367693   PMID:21423190   PMID:21423191   PMID:21474102   PMID:21490601   PMID:21518930   PMID:21731673   PMID:21856776  
PMID:21873635   PMID:21884692   PMID:21931736   PMID:21953612   PMID:22057269   PMID:22223663   PMID:22297846   PMID:22307625   PMID:22325351   PMID:22333916   PMID:22391310   PMID:22441348  
PMID:22496869   PMID:22532304   PMID:22638581   PMID:22733364   PMID:22770845   PMID:22811558   PMID:22864611   PMID:22871220   PMID:22922362   PMID:22989952   PMID:23087373   PMID:23287868  
PMID:23327920   PMID:23359715   PMID:23395962   PMID:23436026   PMID:23449471   PMID:23475113   PMID:23498780   PMID:23506836   PMID:23516383   PMID:23575838   PMID:23616648   PMID:23624624  
PMID:23698124   PMID:23744762   PMID:23792463   PMID:23835259   PMID:23951168   PMID:24040068   PMID:24093534   PMID:24120360   PMID:24137001   PMID:24240174   PMID:24335310   PMID:24449838  
PMID:24451372   PMID:24525021   PMID:24675724   PMID:24681565   PMID:24760871   PMID:24770533   PMID:24808536   PMID:24821725   PMID:24833798   PMID:24924148   PMID:24952961   PMID:24958871  
PMID:25011550   PMID:25178657   PMID:25329411   PMID:25380525   PMID:25609639   PMID:25648995   PMID:25737280   PMID:25758227   PMID:25982413   PMID:26129908   PMID:26167872   PMID:26174178  
PMID:26206133   PMID:26283270   PMID:26287468   PMID:26300473   PMID:26329601   PMID:26365490   PMID:26372908   PMID:26406915   PMID:26447190   PMID:26586441   PMID:26598605   PMID:26603102  
PMID:26604221   PMID:26721795   PMID:26864305   PMID:26921097   PMID:27048565   PMID:27068467   PMID:27448447   PMID:27635759   PMID:27638301   PMID:27668390   PMID:27806305   PMID:27886239  
PMID:27930960   PMID:27935189   PMID:27967209   PMID:28028172   PMID:28053041   PMID:28139683   PMID:28199843   PMID:28202389   PMID:28276480   PMID:28346453   PMID:28402861   PMID:28554894  
PMID:28566502   PMID:28592694   PMID:28656275   PMID:28671696   PMID:28783139   PMID:28791750   PMID:28793257   PMID:28892081   PMID:28949289   PMID:28962688   PMID:28982677   PMID:29035278  
PMID:29042277   PMID:29184203   PMID:29218547   PMID:29459677   PMID:29490983   PMID:29548672   PMID:29599503   PMID:29630406   PMID:29641990   PMID:29712641   PMID:29950483   PMID:30025863  
PMID:30179675   PMID:30186101   PMID:30196744   PMID:30358442   PMID:30375383   PMID:30407865   PMID:30595499   PMID:30628667   PMID:30709655   PMID:30776024   PMID:30926862   PMID:31600191  
PMID:31627491   PMID:31630802   PMID:31796106   PMID:31805977   PMID:31843983   PMID:32098917   PMID:32102981   PMID:32482889   PMID:32647127   PMID:32975918   PMID:32990597  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391036,850,293 - 36,877,885 (+)NCBIGRCm39mm39
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1019.44NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl6113,933,028 - 114,011,308 (-)EnsemblGRCh38hg38GRCh38
GRCh386113,933,028 - 113,971,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376114,254,192 - 114,292,312 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh376114,257,320 - 114,292,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366114,364,019 - 114,399,047 (-)NCBINCBI36hg18NCBI36
Build 346114,368,619 - 114,398,967NCBI
Celera6114,998,693 - 115,033,733 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6111,834,121 - 111,869,161 (-)NCBIHuRef
CHM1_16114,520,179 - 114,555,225 (-)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.22040,548,250 - 40,571,609 (+)NCBI
Rnor_6.0 Ensembl2043,084,870 - 43,108,198 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02043,084,870 - 43,108,198 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02044,811,967 - 44,835,337 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42041,162,093 - 41,186,492 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12041,204,917 - 41,209,275 (+)NCBI
Celera2041,298,790 - 41,322,159 (+)NCBICelera
Cytogenetic Map20q12NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049555262,728,377 - 2,759,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555262,739,099 - 2,759,640 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.16115,802,367 - 115,833,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6115,802,367 - 115,833,004 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06111,731,139 - 111,761,826 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1270,053,297 - 70,103,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11270,053,822 - 70,083,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_0049366792,448,676 - 2,474,641 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl179,863,094 - 79,901,585 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1179,867,713 - 79,901,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2189,929,206 - 89,962,996 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.11359,873,248 - 59,904,542 (+)NCBI
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_0046248564,834,197 - 4,861,546 (+)NCBI

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381037,001,615 - 37,001,840UniSTSGRCm38
MGSCv371036,721,421 - 36,721,646UniSTSGRCm37
Celera1037,894,974 - 37,895,199UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381036,995,764 - 36,996,058UniSTSGRCm38
MGSCv371036,715,570 - 36,715,864UniSTSGRCm37
Celera1037,889,171 - 37,889,465UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381037,001,559 - 37,001,793UniSTSGRCm38
MGSCv371036,721,365 - 36,721,599UniSTSGRCm37
Celera1037,894,918 - 37,895,152UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357813Ath20_matherosclerosis 20 (mouse)Not determined10340743937407588Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10393427237934396Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10453225538532377Mouse
13208561Wght8_mweight 8 (mouse)10500000044000000Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10620194558857699Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10864910542649228Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined101001426844014395Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined101001426844014395Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined101001426844014395Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
10755518Chol16_mcholesterol 16 (mouse)101903904753039047Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102040743956155127Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102171529368255809Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102250000051200000Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102701426846844387Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102984430763844387Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103109840365098534Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103170104065701188Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103390000071000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:748
Count of miRNA genes:473
Interacting mature miRNAs:554
Transcripts:ENSMUST00000019911, ENSMUST00000105510, ENSMUST00000123010, ENSMUST00000128031
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000019911   ⟹   ENSMUSP00000019911
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)Ensembl
RefSeq Acc Id: ENSMUST00000105510   ⟹   ENSMUSP00000101149
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,974,570 - 36,996,111 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123010
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,998,172 - 37,001,611 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128031
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,991,766 - 37,001,888 (+)Ensembl
RefSeq Acc Id: NM_008229   ⟹   NP_032255
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,540 - 36,877,884 (+)NCBI
GRCm381036,974,544 - 37,001,888 (+)NCBI
MGSCv371036,694,350 - 36,721,694 (+)RGD
Celera1037,867,952 - 37,895,247 (+)RGD
RefSeq Acc Id: XM_006512555   ⟹   XP_006512618
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,868 - 36,877,885 (+)NCBI
GRCm381036,974,872 - 37,001,889 (+)NCBI
RefSeq Acc Id: XM_017313806   ⟹   XP_017169295
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,851,085 - 36,877,885 (+)NCBI
GRCm381036,975,089 - 37,001,889 (+)NCBI
RefSeq Acc Id: XM_030244890   ⟹   XP_030100750
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,293 - 36,877,885 (+)NCBI
GRCm381036,974,297 - 37,001,889 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_032255   ⟸   NM_008229
- UniProtKB: P70288 (UniProtKB/Swiss-Prot),   A0A0R4J008 (UniProtKB/TrEMBL),   Q3TMT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512618   ⟸   XM_006512555
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169295   ⟸   XM_017313806
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030100750   ⟸   XM_030244890
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000101149   ⟸   ENSMUST00000105510
RefSeq Acc Id: ENSMUSP00000019911   ⟸   ENSMUST00000019911
Protein Domains

RGD ID:6819426
Promoter ID:MM_KWN:3902
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000049270,   UC007EVE.1
Mouse AssemblyChrPosition (strand)Source
MGSCv361036,693,871 - 36,694,477 (+)MPROMDB
RGD ID:8671796
Promoter ID:EPDNEW_M13929
Type:initiation region
Description:Mus musculus histone deacetylase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm381036,974,547 - 36,974,607EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097691 AgrOrtholog
Ensembl Genes ENSMUSG00000019777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000019911 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000101149 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000019911 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000105510 UniProtKB/TrEMBL
Gene3D-CATH 3.40.800.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro His_deacetylse UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ureohydrolase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15182 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hist_deacetyl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hdac2 PhenoGen
PIRSF His_deacetylse_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Secondary B2RRP3 UniProtKB/Swiss-Prot