Hdac2 (histone deacetylase 2) - Rat Genome Database
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Gene: Hdac2 (histone deacetylase 2) Mus musculus
Analyze
Symbol: Hdac2
Name: histone deacetylase 2
RGD ID: 1312510
MGI Page MGI
Description: Exhibits several functions, including DNA binding activity; Krueppel-associated box domain binding activity; and RNA polymerase II transcription corepressor binding activity. Involved in several processes, including animal organ development; histone modification; and regulation of cell development. Localizes to RNA polymerase II transcription repressor complex and chromosome. Is expressed in several structures, including brain; early conceptus; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human HDAC2 (histone deacetylase 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; Hedgehog signaling pathway; histone modification pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D10Wsu179; D10Wsu179e; HD2; mRPD3; YAF1; YY1 transcription factor-binding protein; Yy1b; Yy1bp
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8022  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391036,850,293 - 36,877,885 (+)NCBIGRCm39mm39
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1019.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(20S)-ginsenoside Rh2  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3',5'-cyclic AMP  (ISO)
3,3'-diindolylmethane  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (EXP)
ammonium chloride  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
capsaicin  (ISO)
choline  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (ISO)
glafenine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
isoprenaline  (EXP,ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
manganese(II) chloride  (ISO)
mechlorethamine  (ISO)
menadione  (ISO)
methoxyacetic acid  (ISO)
mifepristone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nefazodone  (ISO)
nickel subsulfide  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
oxybenzone  (ISO)
pelargonidin  (EXP)
perfluorooctanoic acid  (ISO)
Plantamajoside  (EXP,ISO)
resveratrol  (ISO)
romidepsin  (ISO)
rotenone  (ISO)
sevoflurane  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
tamoxifen  (EXP,ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
valsartan  (EXP,ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
behavioral response to ethanol  (ISO)
cardiac muscle cell development  (IMP)
cardiac muscle hypertrophy  (ISO)
cellular response to dopamine  (ISO)
cellular response to heat  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to trichostatin A  (IDA)
chromatin organization  (TAS)
circadian regulation of gene expression  (IDA)
dendrite development  (IMP)
embryonic digit morphogenesis  (IGI)
epidermal cell differentiation  (IGI)
eyelid development in camera-type eye  (IGI)
fungiform papilla formation  (IGI)
hair follicle placode formation  (IGI)
heterochromatin maintenance  (ISO)
hippocampus development  (IGI)
histone deacetylation  (IGI,ISO)
histone H3 deacetylation  (IBA,IDA,ISO)
histone H3-K27 methylation  (IMP)
histone H4 deacetylation  (IBA,IDA)
negative regulation of apoptotic process  (IGI)
negative regulation of canonical Wnt signaling pathway  (IGI)
negative regulation of cardiac muscle cell proliferation  (IMP)
negative regulation of dendritic spine development  (ISO)
negative regulation of DNA binding  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (IGI)
negative regulation of neuron projection development  (IDA,ISO)
negative regulation of peptidyl-lysine acetylation  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (IGI,IMP)
negative regulation of transcription by RNA polymerase II  (IGI,ISO)
negative regulation of transcription, DNA-templated  (IDA,ISO)
neuron differentiation  (IGI)
odontogenesis of dentin-containing tooth  (IGI)
positive regulation of cell population proliferation  (IGI,ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of interleukin-1 production  (ISO)
positive regulation of male mating behavior  (ISO)
positive regulation of oligodendrocyte differentiation  (IGI,ISO)
positive regulation of proteolysis  (ISO)
positive regulation of signaling receptor activity  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
protein deacetylation  (IDA)
regulation of protein deacetylation  (IGI)
regulation of protein kinase B signaling  (IMP)
regulation of sarcomere organization  (IMP)
response to amphetamine  (ISO)
response to caffeine  (ISO)
response to cocaine  (ISO)
response to drug  (ISO)
response to hyperoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to nicotine  (ISO)
rhythmic process  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiovascular system morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell physiology  (IAGP)
abnormal coat appearance  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart right ventricle morphology  (IAGP)
abnormal hippocampus CA1 region morphology  (IAGP)
abnormal hippocampus pyramidal cell morphology  (IAGP)
abnormal intestinal mucosa morphology  (IAGP)
abnormal large intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal mitosis  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal nail color  (IAGP)
abnormal nail morphology  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal thymus corticomedullary boundary morphology  (IAGP)
abnormal total retina thickness  (IAGP)
abnormal vibrissa morphology  (IAGP)
anemia  (IAGP)
aneuploidy  (IAGP)
arrested B cell differentiation  (IAGP)
arrested T cell differentiation  (IAGP)
cardiac hypertrophy  (IAGP)
chromosomal instability  (IAGP)
cyanosis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased birth body size  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased brain weight  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased heart rate  (IAGP)
decreased intestine length  (IAGP)
decreased megakaryocyte cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased survivor rate  (IAGP)
decreased susceptilbility to retinal ischemic injury  (IAGP)
decreased thymocyte number  (IAGP)
decreased tumor incidence  (IAGP)
diffuse Z line  (IAGP)
dilated heart ventricle  (IAGP)
distended abdomen  (IAGP)
early cellular replicative senescence  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced contextual conditioning behavior  (IAGP)
enhanced long term potentiation  (IAGP)
enlarged chest  (IAGP)
enlarged heart  (IAGP)
enlarged spleen  (IAGP)
enlarged thymus  (IAGP)
hyperkeratosis  (IAGP)
increased apoptosis  (IAGP)
increased B cell apoptosis  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased fibroblast apoptosis  (IAGP)
increased foot pad pigmentation  (IAGP)
increased pulmonary respiratory rate  (IAGP)
increased single-positive T cell number  (IAGP)
increased small intestine adenocarcinoma incidence  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased T cell proliferation  (IAGP)
increased thymocyte apoptosis  (IAGP)
increased thymocyte number  (IAGP)
increased tumor incidence  (IAGP)
insensitivity to growth hormone  (IAGP)
internal hemorrhage  (IAGP)
irregular heartbeat  (IAGP)
lethargy  (IAGP)
narrow eye opening  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
reduced fertility  (IAGP)
short vibrissae  (IAGP)
small testis  (IAGP)
small vertebrae  (IAGP)
thick interventricular septum  (IAGP)
thick ventricular wall  (IAGP)
thrombocytopenia  (IAGP)
thymus hypoplasia  (IAGP)
trisomy  (IAGP)
References

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Additional References at PubMed
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PMID:18454139   PMID:18458156   PMID:18495085   PMID:18501342   PMID:18508077   PMID:18651664   PMID:18754010   PMID:18824292   PMID:18983969   PMID:19015268   PMID:19041327   PMID:19047631  
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PMID:23698124   PMID:23744762   PMID:23792463   PMID:23835259   PMID:23951168   PMID:24040068   PMID:24093534   PMID:24120360   PMID:24137001   PMID:24240174   PMID:24335310   PMID:24449838  
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PMID:28566502   PMID:28592694   PMID:28656275   PMID:28671696   PMID:28783139   PMID:28791750   PMID:28793257   PMID:28892081   PMID:28949289   PMID:28962688   PMID:28982677   PMID:29035278  
PMID:29042277   PMID:29184203   PMID:29218547   PMID:29459677   PMID:29490983   PMID:29548672   PMID:29599503   PMID:29630406   PMID:29641990   PMID:29712641   PMID:29950483   PMID:30025863  
PMID:30179675   PMID:30186101   PMID:30196744   PMID:30358442   PMID:30375383   PMID:30407865   PMID:30595499   PMID:30628667   PMID:30709655   PMID:30776024   PMID:30926862   PMID:31600191  
PMID:31627491   PMID:31630802   PMID:31796106   PMID:31805977   PMID:31843983   PMID:32098917   PMID:32102981   PMID:32482889   PMID:32647127   PMID:32975918   PMID:32990597  


Genomics

Comparative Map Data
Hdac2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391036,850,293 - 36,877,885 (+)NCBIGRCm39mm39
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)EnsemblGRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1019.44NCBI
HDAC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6113,933,028 - 114,011,308 (-)EnsemblGRCh38hg38GRCh38
GRCh386113,933,028 - 113,971,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376114,254,192 - 114,292,312 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh376114,257,320 - 114,292,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366114,364,019 - 114,399,047 (-)NCBINCBI36hg18NCBI36
Build 346114,368,619 - 114,398,967NCBI
Celera6114,998,693 - 115,033,733 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6111,834,121 - 111,869,161 (-)NCBIHuRef
CHM1_16114,520,179 - 114,555,225 (-)NCBICHM1_1
Hdac2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22040,548,250 - 40,571,609 (+)NCBI
Rnor_6.0 Ensembl2043,084,870 - 43,108,198 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02043,084,870 - 43,108,198 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02044,811,967 - 44,835,337 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42041,162,093 - 41,186,492 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12041,204,917 - 41,209,275 (+)NCBI
Celera2041,298,790 - 41,322,159 (+)NCBICelera
Cytogenetic Map20q12NCBI
Hdac2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555262,728,377 - 2,759,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555262,739,099 - 2,759,640 (+)NCBIChiLan1.0ChiLan1.0
HDAC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16115,802,367 - 115,833,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6115,802,367 - 115,833,004 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06111,731,139 - 111,761,826 (-)NCBIMhudiblu_PPA_v0panPan3
HDAC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1270,053,297 - 70,103,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11270,053,822 - 70,083,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Hdac2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366792,448,676 - 2,474,641 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl179,863,094 - 79,901,585 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1179,867,713 - 79,901,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2189,929,206 - 89,962,996 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HDAC2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11359,873,248 - 59,904,542 (+)NCBI
Hdac2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248564,834,197 - 4,861,546 (+)NCBI

Position Markers
RH136178  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381037,001,615 - 37,001,840UniSTSGRCm38
MGSCv371036,721,421 - 36,721,646UniSTSGRCm37
Celera1037,894,974 - 37,895,199UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
UniSTS:236330  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381036,995,764 - 36,996,058UniSTSGRCm38
MGSCv371036,715,570 - 36,715,864UniSTSGRCm37
Celera1037,889,171 - 37,889,465UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
Hdac2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS
D10Wsu179e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381037,001,559 - 37,001,793UniSTSGRCm38
MGSCv371036,721,365 - 36,721,599UniSTSGRCm37
Celera1037,894,918 - 37,895,152UniSTS
Cytogenetic Map10B1UniSTS
cM Map1026.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357813Ath20_matherosclerosis 20 (mouse)Not determined10340743937407588Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10393427237934396Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10453225538532377Mouse
13208561Wght8_mweight 8 (mouse)10500000044000000Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10620194558857699Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10864910542649228Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined101001426844014395Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined101001426844014395Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined101001426844014395Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
10755518Chol16_mcholesterol 16 (mouse)101903904753039047Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102040743956155127Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102171529368255809Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102250000051200000Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102701426846844387Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102984430763844387Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103109840365098534Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103170104065701188Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103390000071000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:748
Count of miRNA genes:473
Interacting mature miRNAs:554
Transcripts:ENSMUST00000019911, ENSMUST00000105510, ENSMUST00000123010, ENSMUST00000128031
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000019911   ⟹   ENSMUSP00000019911
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,974,544 - 37,001,889 (+)Ensembl
RefSeq Acc Id: ENSMUST00000105510   ⟹   ENSMUSP00000101149
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,974,570 - 36,996,111 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123010
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,998,172 - 37,001,611 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1036,991,766 - 37,001,888 (+)Ensembl
RefSeq Acc Id: NM_008229   ⟹   NP_032255
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,540 - 36,877,884 (+)NCBI
GRCm381036,974,544 - 37,001,888 (+)NCBI
MGSCv371036,694,350 - 36,721,694 (+)RGD
Celera1037,867,952 - 37,895,247 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512555   ⟹   XP_006512618
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,868 - 36,877,885 (+)NCBI
GRCm381036,974,872 - 37,001,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313806   ⟹   XP_017169295
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,851,085 - 36,877,885 (+)NCBI
GRCm381036,975,089 - 37,001,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030244890   ⟹   XP_030100750
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391036,850,293 - 36,877,885 (+)NCBI
GRCm381036,974,297 - 37,001,889 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032255   ⟸   NM_008229
- UniProtKB: P70288 (UniProtKB/Swiss-Prot),   A0A0R4J008 (UniProtKB/TrEMBL),   Q3TMT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512618   ⟸   XM_006512555
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169295   ⟸   XM_017313806
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030100750   ⟸   XM_030244890
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000101149   ⟸   ENSMUST00000105510
RefSeq Acc Id: ENSMUSP00000019911   ⟸   ENSMUST00000019911
Protein Domains
Hist_deacetyl

Promoters
RGD ID:6819426
Promoter ID:MM_KWN:3902
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000049270,   UC007EVE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361036,693,871 - 36,694,477 (+)MPROMDB
RGD ID:8671796
Promoter ID:EPDNEW_M13929
Type:initiation region
Name:Hdac2_1
Description:Mus musculus histone deacetylase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381036,974,547 - 36,974,607EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097691 AgrOrtholog
Ensembl Genes ENSMUSG00000019777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000019911 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000101149 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000019911 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000105510 UniProtKB/TrEMBL
Gene3D-CATH 3.40.800.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro His_deacetylse UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ureohydrolase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15182 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1097691 ENTREZGENE
NCBI Gene 15182 ENTREZGENE
Pfam Hist_deacetyl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hdac2 PhenoGen
PIRSF His_deacetylse_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HDASUPER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISDACETLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J008 ENTREZGENE, UniProtKB/TrEMBL
  HDAC2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TMT1 ENTREZGENE, UniProtKB/TrEMBL
  Q3URA2_MOUSE UniProtKB/TrEMBL
  Q3UXH8_MOUSE UniProtKB/TrEMBL
  Q8BQ10_MOUSE UniProtKB/TrEMBL
UniProt Secondary B2RRP3 UniProtKB/Swiss-Prot