Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Smyd5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SMYD5 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SMYD5 mRNA | CTD | PMID:36331819 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMYD5 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SMYD5 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SMYD5 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMYD5 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SMYD5 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SMYD5 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SMYD5 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4-dinitrotoluene | affects expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of SMYD5 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SMYD5 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SMYD5 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Smyd5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SMYD5 mRNA | CTD | PMID:36041667 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of SMYD5 mRNA | CTD | PMID:21346803 | aconitine | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Aconitine results in increased expression of SMYD5 protein | CTD | PMID:33236894 | acrylamide | decreases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SMYD5 mRNA | CTD | PMID:32763439 | amphetamine | decreases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of SMYD5 mRNA | CTD | PMID:30779732 | arsane | affects methylation | ISO | SMYD5 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SMYD5 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | SMYD5 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SMYD5 gene | CTD | PMID:25304211 | atrazine | increases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Atrazine results in increased expression of SMYD5 mRNA | CTD | PMID:22378314 | bisphenol A | affects expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SMYD5 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | Smyd5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SMYD5 mRNA | CTD | PMID:36041667 | bisphenol A | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SMYD5 mRNA | CTD | PMID:34947998 | bisphenol F | multiple interactions | ISO | Smyd5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SMYD5 mRNA | CTD | PMID:36041667 | cadmium atom | multiple interactions | ISO | SMYD5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SMYD5 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | SMYD5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SMYD5 mRNA | CTD | PMID:35301059 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | SMYD5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SMYD5 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SMYD5 mRNA | CTD | PMID:37019170 | cobalt dichloride | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of SMYD5 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SMYD5 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SMYD5 mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of SMYD5 mRNA | CTD | PMID:19770486 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SMYD5 mRNA | CTD | PMID:30529165 | endosulfan | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SMYD5 mRNA | CTD | PMID:29391264 | enzyme inhibitor | multiple interactions | ISO | SMYD5 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SMYD5 protein | CTD | PMID:23301498 | flutamide | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of SMYD5 mRNA | CTD | PMID:24136188 | indole-3-methanol | affects expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of SMYD5 mRNA | CTD | PMID:21396975 | lead diacetate | increases methylation | ISO | Smyd5 (Rattus norvegicus) | 6480464 | lead acetate results in increased methylation of SMYD5 gene | CTD | PMID:29571894 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SMYD5 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SMYD5 mRNA | CTD | PMID:33387578 | paraquat | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of SMYD5 mRNA | CTD | PMID:32680482 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of SMYD5 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SMYD5 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in increased expression of SMYD5 mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Phenobarbital results in decreased expression of SMYD5 mRNA | CTD | PMID:19162173 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SMYD5 mRNA | CTD | PMID:18301758 | resveratrol | multiple interactions | ISO | SMYD5 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SMYD5 mRNA | CTD | PMID:23557933 | tetrachloromethane | multiple interactions | ISO | Smyd5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SMYD5 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of SMYD5 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Smyd5 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of SMYD5 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichostatin A | affects expression | ISO | SMYD5 (Homo sapiens) | 6480464 | trichostatin A affects the expression of SMYD5 mRNA | CTD | PMID:28542535 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of SMYD5 mRNA | CTD | PMID:19042947 | urethane | decreases expression | ISO | SMYD5 (Homo sapiens) | 6480464 | Urethane results in decreased expression of SMYD5 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of SMYD5 mRNA | CTD | PMID:17292431 | valproic acid | decreases methylation | ISO | SMYD5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SMYD5 gene | CTD | PMID:29154799 | |