Mrps22 (mitochondrial ribosomal protein S22) - Rat Genome Database

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Gene: Mrps22 (mitochondrial ribosomal protein S22) Mus musculus
Analyze
Symbol: Mrps22
Name: mitochondrial ribosomal protein S22
RGD ID: 1616801
MGI Page MGI
Description: Predicted to be a structural constituent of ribosome. Localizes to mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina; and spleen. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Orthologous to human MRPS22 (mitochondrial ribosomal protein S22); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 28S ribosomal protein S22, mitochondrial; 3100002P07Rik; MRP-S22; ribosomal protein, mitochondrial, S22; Rpm; Rpms22; S22mt
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,470,783 - 98,483,732 (-)NCBIGRCm39mm39
GRCm39 Ensembl998,470,783 - 98,483,713 (-)Ensembl
GRCm38998,588,730 - 98,601,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,588,730 - 98,601,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv37998,489,149 - 98,502,098 (-)NCBIGRCm37mm9NCBIm37
MGSCv36998,398,089 - 98,411,011 (-)NCBImm8
Celera998,134,359 - 98,147,288 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10938081   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14651853   PMID:15081106   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:18614015   PMID:21873635   PMID:22904065   PMID:24565867   PMID:28378742   PMID:29566152   PMID:30196744   PMID:31077711   PMID:31138677   PMID:32098917  
PMID:32325033   PMID:32376682   PMID:32987154  


Genomics

Comparative Map Data
Mrps22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,470,783 - 98,483,732 (-)NCBIGRCm39mm39
GRCm39 Ensembl998,470,783 - 98,483,713 (-)Ensembl
GRCm38998,588,730 - 98,601,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,588,730 - 98,601,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv37998,489,149 - 98,502,098 (-)NCBIGRCm37mm9NCBIm37
MGSCv36998,398,089 - 98,411,011 (-)NCBImm8
Celera998,134,359 - 98,147,288 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
MRPS22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3139,005,806 - 139,357,223 (+)EnsemblGRCh38hg38GRCh38
GRCh383139,343,994 - 139,357,140 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373139,062,836 - 139,075,982 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,545,551 - 140,558,578 (+)NCBINCBI36hg18NCBI36
Build 343140,545,558 - 140,558,583NCBI
Celera3137,485,814 - 137,498,839 (+)NCBI
Cytogenetic Map3q23NCBI
HuRef3136,438,309 - 136,451,335 (+)NCBIHuRef
CHM1_13139,026,426 - 139,039,453 (+)NCBICHM1_1
Mrps22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2899,184,110 - 99,197,278 (-)NCBI
Rnor_6.0 Ensembl8106,604,379 - 106,617,597 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08106,604,421 - 106,617,591 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,047,828 - 106,060,998 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera898,592,165 - 98,605,335 (-)NCBICelera
Cytogenetic Map8q31NCBI
Mrps22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555086,232,514 - 6,246,633 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555086,232,514 - 6,246,593 (-)NCBIChiLan1.0ChiLan1.0
MRPS22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13143,638,771 - 143,993,852 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3143,980,670 - 143,993,842 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03136,380,963 - 136,394,148 (+)NCBIMhudiblu_PPA_v0panPan3
MRPS22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,508,478 - 35,536,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,496,961 - 35,524,082 (+)NCBI
ROS_Cfam_1.02336,047,616 - 36,074,786 (+)NCBI
UMICH_Zoey_3.12335,728,105 - 35,755,240 (+)NCBI
UNSW_CanFamBas_1.02335,801,180 - 35,828,369 (+)NCBI
UU_Cfam_GSD_1.02336,043,257 - 36,070,586 (+)NCBI
Mrps22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,712,076 - 74,726,839 (+)NCBI
SpeTri2.0NW_0049365401,451,882 - 1,466,569 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,981,676 - 80,232,774 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,006,656 - 80,232,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21387,874,586 - 87,894,354 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS22
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11551,198,515 - 51,211,587 (-)NCBI
ChlSab1.1 Ensembl1551,198,553 - 51,211,532 (-)Ensembl
Mrps22
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473015,894,624 - 15,908,069 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96936046598819654Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:48
Interacting mature miRNAs:50
Transcripts:ENSMUST00000035034
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000035034   ⟹   ENSMUSP00000035034
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,588,730 - 98,601,660 (-)Ensembl
RefSeq Acc Id: ENSMUST00000190150
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,595,176 - 98,601,645 (-)Ensembl
RefSeq Acc Id: NM_025485   ⟹   NP_079761
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,470,783 - 98,483,732 (-)NCBI
GRCm38998,588,730 - 98,601,679 (-)ENTREZGENE
MGSCv37998,489,149 - 98,502,098 (-)RGD
Celera998,134,359 - 98,147,288 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079761   ⟸   NM_025485
- UniProtKB: Q9CXW2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035034   ⟸   ENSMUST00000035034

Promoters
RGD ID:6844822
Promoter ID:MM_KWN:58468
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_025485,   UC009RDO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36998,501,799 - 98,502,299 (-)MPROMDB
RGD ID:8670538
Promoter ID:EPDNEW_M13300
Type:multiple initiation site
Name:Mrps22_1
Description:Mus musculus mitochondrial ribosomal protein S22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,601,664 - 98,601,724EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928137 AgrOrtholog
Ensembl Genes ENSMUSG00000032459 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000035034 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000035034 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Ribosomal_S22_mit UniProtKB/Swiss-Prot
KEGG Report mmu:64655 UniProtKB/Swiss-Prot
MGD MGI:1928137 ENTREZGENE
NCBI Gene 64655 ENTREZGENE
PANTHER PTHR13071 UniProtKB/Swiss-Prot
Pfam MRP-S22 UniProtKB/Swiss-Prot
PhenoGen Mrps22 PhenoGen
UniProt Q9CXW2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3U3T2 UniProtKB/Swiss-Prot
  Q8VDG9 UniProtKB/Swiss-Prot
  Q9D185 UniProtKB/Swiss-Prot