Fhod3 (formin homology 2 domain containing 3) - Rat Genome Database

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Gene: Fhod3 (formin homology 2 domain containing 3) Mus musculus
Analyze
Symbol: Fhod3
Name: formin homology 2 domain containing 3
RGD ID: 1621343
MGI Page MGI
Description: Predicted to enable actin filament binding activity. Acts upstream of or within cardiac myofibril assembly; negative regulation of actin filament polymerization; and sarcomere organization. Predicted to be located in striated muscle thin filament. Predicted to be active in cytoplasm and cytoskeleton. Is expressed in several structures, including axial skeleton; central nervous system; gut; heart; and metanephros. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy. Orthologous to human FHOD3 (formin homology 2 domain containing 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A930009H06Rik; FH1/FH2 domain-containing protein 3; FHOS2; formin homolog overexpressed in spleen 2; formin-family protein FHOS2; KIAA1695; mFHOS2; mKIAA1695
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,841,445 - 25,266,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1824,841,680 - 25,266,558 (+)EnsemblGRCm39 Ensembl
GRCm381824,708,388 - 25,133,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1824,708,623 - 25,133,501 (+)EnsemblGRCm38mm10GRCm38
MGSCv371824,867,946 - 25,292,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361824,852,455 - 25,276,511 (+)NCBIMGSCv36mm8
Celera1825,190,970 - 25,619,254 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1813.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
aconitine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fulvestrant  (ISO)
glyphosate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
nickel atom  (ISO)
nitrofen  (ISO)
O-methyleugenol  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP)
sulforaphane  (EXP)
tert-butyl hydroperoxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
XL147  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15966898   PMID:16141072   PMID:16141073  
PMID:18799693   PMID:19658189   PMID:19706596   PMID:21267068   PMID:21873635   PMID:22509354   PMID:23052206   PMID:23213483   PMID:26272686   PMID:26848968   PMID:28438902   PMID:29158260  
PMID:29686099   PMID:30573686   PMID:31008549   PMID:32325033   PMID:33251537   PMID:34321999   PMID:36627242  


Genomics

Comparative Map Data
Fhod3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,841,445 - 25,266,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1824,841,680 - 25,266,558 (+)EnsemblGRCm39 Ensembl
GRCm381824,708,388 - 25,133,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1824,708,623 - 25,133,501 (+)EnsemblGRCm38mm10GRCm38
MGSCv371824,867,946 - 25,292,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361824,852,455 - 25,276,511 (+)NCBIMGSCv36mm8
Celera1825,190,970 - 25,619,254 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1813.18NCBI
FHOD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381836,297,713 - 36,780,220 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1836,297,713 - 36,780,220 (+)EnsemblGRCh38hg38GRCh38
GRCh371833,877,676 - 34,360,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361832,131,700 - 32,614,016 (+)NCBINCBI36Build 36hg18NCBI36
Celera1830,685,614 - 31,169,391 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1830,735,778 - 31,218,907 (+)NCBIHuRef
CHM1_11833,804,792 - 34,287,049 (+)NCBICHM1_1
T2T-CHM13v2.01836,489,301 - 36,973,364 (+)NCBIT2T-CHM13v2.0
Fhod3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81816,267,830 - 16,700,508 (+)NCBIGRCr8
mRatBN7.21815,993,079 - 16,425,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1815,993,324 - 16,425,796 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1816,172,154 - 16,612,274 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01816,954,859 - 17,394,934 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01816,242,926 - 16,674,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01816,650,786 - 17,332,209 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1816,650,806 - 17,332,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01816,410,820 - 16,473,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01816,842,427 - 17,086,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41816,487,052 - 16,952,424 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11816,513,673 - 16,615,841 (+)NCBI
Celera1815,913,907 - 16,336,469 (+)NCBICelera
Cytogenetic Map18p12NCBI
Fhod3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540222,821,710 - 23,279,222 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540222,822,060 - 23,277,993 (+)NCBIChiLan1.0ChiLan1.0
FHOD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21753,693,335 - 54,176,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11839,385,954 - 39,882,417 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01829,550,049 - 30,033,130 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11833,163,910 - 33,590,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1833,165,819 - 33,590,154 (+)Ensemblpanpan1.1panPan2
FHOD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1753,477,273 - 53,933,532 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl753,478,930 - 53,934,331 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha752,893,761 - 53,356,825 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0753,438,086 - 53,901,223 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl753,438,079 - 53,901,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1753,122,091 - 53,584,883 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0753,144,927 - 53,608,076 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0753,437,853 - 53,900,540 (-)NCBIUU_Cfam_GSD_1.0
Fhod3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494449,286,982 - 49,717,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365178,614,867 - 9,044,894 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365178,614,384 - 9,044,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FHOD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6120,036,845 - 120,586,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16120,036,824 - 120,585,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26112,902,155 - 113,225,109 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FHOD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11844,053,360 - 44,540,820 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1844,049,837 - 44,540,760 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605018,601,155 - 18,998,789 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fhod3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477910,562,296 - 11,069,694 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477910,562,319 - 11,069,557 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fhod3
14428 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:188
Count of miRNA genes:157
Interacting mature miRNAs:178
Transcripts:ENSMUST00000037097
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128893823Mouse
12801462Intim3_mintima modifier 3 (mouse)18131720756Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131720756Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133547739Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133547739Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18808696442087106Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181363712647637126Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181619964050199776Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181813970452139859Mouse
12910787Pwbwq18_mpost-weaning body weight QTL 18 (mouse)181826552930570819Mouse
12910805Pwbwq17_mpost-weaning body weight QTL 17 (mouse)181826552930570819Mouse
12910819Ogrq6_moverall growth rate QTL 6 (mouse)181826552930570819Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181901887453018992Mouse
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181901887453018992Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182121758055217727Mouse
1301950Otx2m1_morthodenticle homolog 2 (Drosophila) modifier 1 (mouse)Not determined182156868236187740Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182261991456620127Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182261991456620127Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182261991456620127Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182261991456620127Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182261991456620127Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182411556058115730Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse

Markers in Region
12.MMHAP18FLD3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381824,763,135 - 24,763,295UniSTSGRCm38
MGSCv371824,921,636 - 24,921,796UniSTSGRCm37
Celera1825,246,553 - 25,246,713UniSTS
Cytogenetic Map18A2UniSTS
Whitehead_YAC18 UniSTS
D18Mit22  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381824,953,907 - 24,954,049UniSTSGRCm38
MGSCv371825,112,408 - 25,112,550UniSTSGRCm37
Celera1825,438,080 - 25,438,222UniSTS
Cytogenetic Map18A2UniSTS
cM Map188.7UniSTS
Whitehead Genetic188.7UniSTS
Whitehead/MRC_RH18409.29UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001289654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006525828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006525830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB078608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB078609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000037097   ⟹   ENSMUSP00000041361
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1824,842,502 - 25,266,558 (+)Ensembl
GRCm38.p6 Ensembl1824,709,445 - 25,133,501 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234199
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1825,257,418 - 25,263,751 (+)Ensembl
GRCm38.p6 Ensembl1825,124,361 - 25,130,694 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234462
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1824,841,680 - 24,904,593 (+)Ensembl
GRCm38.p6 Ensembl1824,708,623 - 24,771,536 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234526   ⟹   ENSMUSP00000157193
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1824,842,502 - 25,266,558 (+)Ensembl
GRCm38.p6 Ensembl1824,709,445 - 25,133,501 (+)Ensembl
RefSeq Acc Id: ENSMUST00000234834   ⟹   ENSMUSP00000157226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1824,842,502 - 25,266,558 (+)Ensembl
GRCm38.p6 Ensembl1824,709,445 - 25,133,501 (+)Ensembl
RefSeq Acc Id: NM_001289654   ⟹   NP_001276583
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,680 - 25,266,564 (+)NCBI
GRCm381824,708,623 - 25,133,507 (+)NCBI
Celera1825,190,146 - 25,619,260 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289655   ⟹   NP_001276584
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,680 - 25,266,564 (+)NCBI
GRCm381824,708,623 - 25,133,507 (+)NCBI
Celera1825,190,146 - 25,619,260 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001403900   ⟹   NP_001390829
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,680 - 25,266,564 (+)NCBI
RefSeq Acc Id: NM_175276   ⟹   NP_780485
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,680 - 25,266,564 (+)NCBI
GRCm381824,708,623 - 25,133,507 (+)NCBI
MGSCv371824,867,946 - 25,292,002 (+)RGD
Celera1825,190,146 - 25,619,260 (+)NCBI
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006525828   ⟹   XP_006525891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,445 - 25,266,558 (+)NCBI
GRCm381824,708,388 - 25,133,501 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006525830   ⟹   XP_006525893
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391824,841,445 - 25,266,558 (+)NCBI
GRCm381824,708,388 - 25,133,501 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_780485   ⟸   NM_175276
- Peptide Label: isoform 1
- UniProtKB: Q76HP7 (UniProtKB/Swiss-Prot),   Q5DTV7 (UniProtKB/Swiss-Prot),   B2RQR3 (UniProtKB/Swiss-Prot),   Q76LL5 (UniProtKB/Swiss-Prot),   Q76LL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006525893   ⟸   XM_006525830
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006525891   ⟸   XM_006525828
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001276584   ⟸   NM_001289655
- Peptide Label: isoform 3
- UniProtKB: Q76LL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276583   ⟸   NM_001289654
- Peptide Label: isoform 2
- UniProtKB: Q76LL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000041361   ⟸   ENSMUST00000037097
RefSeq Acc Id: ENSMUSP00000157226   ⟸   ENSMUST00000234834
RefSeq Acc Id: ENSMUSP00000157193   ⟸   ENSMUST00000234526
RefSeq Acc Id: NP_001390829   ⟸   NM_001403900
- Peptide Label: isoform 4
Protein Domains
DAD   FH1   FH2   GBD/FH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76LL6-F1-model_v2 AlphaFold Q76LL6 1-1578 view protein structure

Promoters
RGD ID:13677274
Promoter ID:EPDNEW_M22786
Type:single initiation site
Name:Fhod3_2
Description:Mus musculus formin homology 2 domain containing 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22787  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381824,708,623 - 24,708,683EPDNEW
RGD ID:13677276
Promoter ID:EPDNEW_M22787
Type:initiation region
Name:Fhod3_1
Description:Mus musculus formin homology 2 domain containing 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22786  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381824,709,483 - 24,709,543EPDNEW
RGD ID:6829266
Promoter ID:MM_KWN:24784
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Kidney,   Liver,   Lung
Transcripts:AK020839_GM9955,   ENSMUST00000115819,   ENSMUST00000115820,   NM_175276,   UC008EHA.1,   UC008EHC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361824,867,696 - 24,868,196 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925847 AgrOrtholog
Ensembl Genes ENSMUSG00000034295 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037097 ENTREZGENE
  ENSMUST00000037097.9 UniProtKB/Swiss-Prot
  ENSMUST00000234526 ENTREZGENE
  ENSMUST00000234526.2 UniProtKB/Swiss-Prot
  ENSMUST00000234834 ENTREZGENE
  ENSMUST00000234834.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.2220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/Swiss-Prot
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  DAD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2_Formin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FHOD1_GBD_N UniProtKB/Swiss-Prot
  GBD/FH3_dom UniProtKB/Swiss-Prot
KEGG Report mmu:225288 UniProtKB/Swiss-Prot
MGD MGI:1925847 ENTREZGENE
NCBI Gene 225288 ENTREZGENE
PANTHER FH1/FH2 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formin_GBD_N UniProtKB/Swiss-Prot
PhenoGen Fhod3 PhenoGen
PROSITE DAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/Swiss-Prot
SMART FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot
UniProt B2RQR3 ENTREZGENE
  FHOD3_MOUSE UniProtKB/Swiss-Prot
  Q5DTV7 ENTREZGENE
  Q6P9T5_MOUSE UniProtKB/TrEMBL
  Q76HP7 ENTREZGENE
  Q76LL5 ENTREZGENE
  Q76LL6 ENTREZGENE
UniProt Secondary B2RQR3 UniProtKB/Swiss-Prot
  Q5DTV7 UniProtKB/Swiss-Prot
  Q76HP7 UniProtKB/Swiss-Prot
  Q76LL5 UniProtKB/Swiss-Prot