H2-T23 (histocompatibility 2, T region locus 23) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: H2-T23 (histocompatibility 2, T region locus 23) Mus musculus
Analyze
Symbol: H2-T23
Name: histocompatibility 2, T region locus 23
RGD ID: 1558332
MGI Page MGI
Description: Predicted to enable beta-2-microglobulin binding activity; peptide antigen binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; inner ear development; and positive regulation of T cell mediated cytotoxicity. Predicted to be located in cell surface and plasma membrane. Predicted to be part of MHC class I protein complex and MHC class Ib protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and small intestine. Human ortholog(s) of this gene implicated in occupational asthma. Orthologous to human HLA-E (major histocompatibility complex, class I, E).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 37b; 37c; H-2 class I histocompatibility antigen, D-37 alpha chain; H-2T23; H2-K1; H2-Qa1; MGC117681; MHC class I antigen Qa1; MHC class II antigen K; MHC classIb Qa1; Qa; Qa-; Qa-1; Qa-1(b); Qa1; Qed-1; T18c; T18c(37); T23b; T23d
RGD Orthologs
Human
Rat
Bonobo
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,340,869 - 36,343,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,340,665 - 36,343,747 (-)EnsemblGRCm39 Ensembl
GRCm381736,029,977 - 36,032,701 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,029,773 - 36,032,855 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,166,922 - 36,169,646 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,638,030 - 35,640,754 (-)NCBIMGSCv36mm8
Celera1739,547,532 - 39,600,702 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (EXP)
2,6-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxynon-2-enal  (EXP)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aconitine  (ISO)
all-trans-retinoic acid  (ISO)
ammonium acetate  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cefuroxime  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
ciprofloxacin  (ISO)
clindamycin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
etoposide  (ISO)
famotidine  (ISO)
ferric oxide  (EXP)
ferroheme b  (EXP)
fumonisin B1  (EXP)
gentamycin  (ISO)
heme b  (EXP)
hydrochlorothiazide  (ISO)
inulin  (EXP)
isotretinoin  (ISO)
ketorolac  (ISO)
lincomycin  (ISO)
malathion  (ISO)
menadione  (ISO)
methidathion  (EXP)
methylmercury chloride  (EXP)
methylparaben  (ISO)
mifepristone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
ochratoxin A  (ISO)
ofloxacin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
progesterone  (ISO)
quercitrin  (ISO)
resveratrol  (EXP)
selenium atom  (ISO)
simvastatin  (ISO)
succimer  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
tolmetin  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
troglitazone  (EXP)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (ISO)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent  (IBA)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib  (IBA)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent  (IDA)
antigen processing and presentation of exogenous peptide antigen via MHC class Ib  (ISO)
antigen processing and presentation of peptide antigen via MHC class I  (IEA)
CD8-positive, alpha-beta T cell activation  (ISO)
immune response  (IBA)
immune system process  (IEA)
inner ear development  (IDA)
natural killer cell tolerance induction  (ISO)
negative regulation of natural killer cell activation  (ISO)
negative regulation of natural killer cell mediated cytotoxicity  (ISO)
negative regulation of T cell proliferation  (ISO)
positive regulation of antibody-dependent cellular cytotoxicity  (ISO)
positive regulation of CD8-positive, alpha-beta T cell activation  (ISO)
positive regulation of CD8-positive, alpha-beta T cell proliferation  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-13 production  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of natural killer cell activation  (ISO)
positive regulation of natural killer cell cytokine production  (ISO)
positive regulation of natural killer cell mediated cytotoxicity  (ISO)
positive regulation of natural killer cell mediated immunity  (ISO)
positive regulation of natural killer cell proliferation  (ISO)
positive regulation of T cell mediated cytotoxicity  (IBA,IDA)
positive regulation of TRAIL production  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
protection from natural killer cell mediated cytotoxicity  (ISO)
regulation of natural killer cell mediated immunity  (ISO)
T cell mediated cytotoxicity  (IDA)

References

References - curated
# Reference Title Reference Citation
1. Fine map of a region homologous to the rat grc complex in the TL region of the mouse. Hunt SW 3rd, etal., Immunogenetics 1993;37(5):386-9.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Genetic and molecular mapping of the Hmt region of mouse. Richards S, etal., EMBO J 1989 Dec 1;8(12):3749-57.
8. Clusters of genes encoding mouse transplantation antigens. Steinmetz M, etal., Cell 1982 Mar;28(3):489-98.
9. Genetic variants in the major histocompatibility complex class I and class II genes are associated with diisocyanate-induced Asthma. Yucesoy B, etal., J Occup Environ Med. 2014 Apr;56(4):382-7. doi: 10.1097/JOM.0000000000000138.
Additional References at PubMed
PMID:75870   PMID:1538753   PMID:1968929   PMID:2379238   PMID:2416805   PMID:2580784   PMID:2793207   PMID:3036997   PMID:3838699   PMID:3925004   PMID:6399516   PMID:6822734  
PMID:6967411   PMID:6978819   PMID:7026427   PMID:7276576   PMID:7836920   PMID:8245452   PMID:9730897   PMID:10047540   PMID:10349636   PMID:10369933   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11908948   PMID:12466851   PMID:12477932   PMID:12902470   PMID:14734748   PMID:15098030   PMID:15517242   PMID:16141072   PMID:16141073   PMID:17202325   PMID:17509909  
PMID:17878358   PMID:18028286   PMID:18096998   PMID:18416856   PMID:18541714   PMID:19047627   PMID:20844537   PMID:21233417   PMID:21267068   PMID:21677750   PMID:21738737   PMID:21795542  
PMID:21873193   PMID:21873635   PMID:22001201   PMID:22008794   PMID:22084437   PMID:22131332   PMID:22522492   PMID:23002042   PMID:24324159   PMID:24958902   PMID:25552357   PMID:27272249  
PMID:28475642   PMID:28740236   PMID:28894277   PMID:29186689   PMID:29358051   PMID:30503208   PMID:30970256   PMID:31907392   PMID:31992596   PMID:32012249   PMID:32111690   PMID:32554809  
PMID:32968282   PMID:33020145   PMID:33674442   PMID:33765134   PMID:34911745   PMID:35648829   PMID:38022509  


Genomics

Comparative Map Data
H2-T23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,340,869 - 36,343,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,340,665 - 36,343,747 (-)EnsemblGRCm39 Ensembl
GRCm381736,029,977 - 36,032,701 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,029,773 - 36,032,855 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,166,922 - 36,169,646 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,638,030 - 35,640,754 (-)NCBIMGSCv36mm8
Celera1739,547,532 - 39,600,702 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.86NCBI
HLA-E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,489,509 - 30,494,194 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,489,509 - 30,494,194 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,457,286 - 30,461,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,565,250 - 30,569,077 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,565,287 - 30,568,337NCBI
Celera632,055,310 - 32,060,109 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef630,257,312 - 30,262,111 (+)NCBIHuRef
CHM1_1630,459,288 - 30,464,087 (+)NCBICHM1_1
T2T-CHM13v2.0630,353,696 - 30,358,381 (+)NCBIT2T-CHM13v2.0
RT1-A2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,872,720 - 4,876,425 (+)NCBIGRCr8
mRatBN7.2204,870,939 - 4,910,183 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0205,374,990 - 5,378,536 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,374,985 - 5,378,539 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,433,437 - 7,436,984 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,021,816 - 5,025,341 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,470,599 - 6,474,124 (+)NCBICelera
Cytogenetic Map20p12NCBI
LOC100977055
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,048,829 - 45,053,645 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,011,935 - 41,016,698 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,233,293 - 30,238,056 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,104,186 - 31,108,978 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,101,251 - 31,107,262 (+)Ensemblpanpan1.1panPan2

Variants

.
Variants in H2-T23
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:474
Count of miRNA genes:346
Interacting mature miRNAs:381
Transcripts:ENSMUST00000102678, ENSMUST00000174161, ENSMUST00000174471, ENSMUST00000174839
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse

Markers in Region
BE199223  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381736,117,162 - 36,117,305UniSTSGRCm38
GRCm381736,038,482 - 36,038,625UniSTSGRCm38
MGSCv371736,254,107 - 36,254,250UniSTSGRCm37
MGSCv371736,175,427 - 36,175,570UniSTSGRCm37
Celera1739,555,640 - 39,555,783UniSTS
Celera1735,483,091 - 35,483,234UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.97UniSTS
cM Map1719.74UniSTS
cM Map1719.96UniSTS
cM Map1719.73UniSTS
Whitehead/MRC_RH17491.27UniSTS
33.MMHAP25FLC6.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381736,112,735 - 36,112,903UniSTSGRCm38
GRCm381736,033,751 - 36,033,919UniSTSGRCm38
MGSCv371736,170,696 - 36,170,864UniSTSGRCm37
MGSCv371736,249,680 - 36,249,848UniSTSGRCm37
Cytogenetic Map17B1UniSTS
cM Map1719.73UniSTS
Whitehead_YAC17 UniSTS
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS
H2-T23  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381736,031,035 - 36,032,251UniSTSGRCm38
MGSCv371736,167,980 - 36,169,196UniSTSGRCm37
Celera1739,548,590 - 39,549,806UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.73UniSTS
D11Bhm20  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map12D1UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map4E1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map13D2UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map16C4UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map7B1-B2UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map11A3.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map19BUniSTS
cM Map1144.15UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB359230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC112970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF041855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF057279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF082510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU406999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L00606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000102678   ⟹   ENSMUSP00000099739
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1736,340,868 - 36,343,747 (-)Ensembl
GRCm38.p6 Ensembl1736,029,976 - 36,032,855 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1736,340,665 - 36,343,433 (-)Ensembl
GRCm38.p6 Ensembl1736,029,773 - 36,032,541 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1736,342,655 - 36,343,622 (-)Ensembl
GRCm38.p6 Ensembl1736,031,763 - 36,032,730 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174839
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1736,340,912 - 36,343,582 (-)Ensembl
GRCm38.p6 Ensembl1736,030,020 - 36,032,690 (-)Ensembl
RefSeq Acc Id: NM_010398   ⟹   NP_034528
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391736,340,869 - 36,343,593 (-)NCBI
GRCm381736,029,977 - 36,032,701 (-)NCBI
MGSCv371736,166,922 - 36,169,646 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_034528 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16900 (Get FASTA)   NCBI Sequence Viewer  
  AAA39693 (Get FASTA)   NCBI Sequence Viewer  
  AAA60728 (Get FASTA)   NCBI Sequence Viewer  
  AAD12244 (Get FASTA)   NCBI Sequence Viewer  
  AAD28334 (Get FASTA)   NCBI Sequence Viewer  
  AAD28335 (Get FASTA)   NCBI Sequence Viewer  
  AAD28338 (Get FASTA)   NCBI Sequence Viewer  
  AAD28339 (Get FASTA)   NCBI Sequence Viewer  
  AAD28340 (Get FASTA)   NCBI Sequence Viewer  
  AAD28341 (Get FASTA)   NCBI Sequence Viewer  
  AAD28342 (Get FASTA)   NCBI Sequence Viewer  
  AAD31381 (Get FASTA)   NCBI Sequence Viewer  
  AAD53968 (Get FASTA)   NCBI Sequence Viewer  
  AAH05648 (Get FASTA)   NCBI Sequence Viewer  
  AAH99472 (Get FASTA)   NCBI Sequence Viewer  
  AWY63865 (Get FASTA)   NCBI Sequence Viewer  
  AWY63866 (Get FASTA)   NCBI Sequence Viewer  
  AWY63867 (Get FASTA)   NCBI Sequence Viewer  
  AWY63868 (Get FASTA)   NCBI Sequence Viewer  
  AWY63869 (Get FASTA)   NCBI Sequence Viewer  
  AWY63872 (Get FASTA)   NCBI Sequence Viewer  
  AWY63873 (Get FASTA)   NCBI Sequence Viewer  
  AWY63874 (Get FASTA)   NCBI Sequence Viewer  
  AWY63875 (Get FASTA)   NCBI Sequence Viewer  
  AWY63891 (Get FASTA)   NCBI Sequence Viewer  
  BAE21691 (Get FASTA)   NCBI Sequence Viewer  
  BAF76150 (Get FASTA)   NCBI Sequence Viewer  
  CAA68665 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000099739
  ENSMUSP00000099739.5
GenBank Protein P06339 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034528   ⟸   NM_010398
- Peptide Label: precursor
- UniProtKB: P06339 (UniProtKB/Swiss-Prot),   Q3V014 (UniProtKB/TrEMBL),   O98032 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000099739   ⟸   ENSMUST00000102678
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06339-F1-model_v2 AlphaFold P06339 1-357 view protein structure

Promoters
RGD ID:13675962
Promoter ID:EPDNEW_M22130
Type:initiation region
Name:H2-T23_1
Description:Mus musculus histocompatibility 2, T region locus 23 (H2-T23),mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381736,032,701 - 36,032,761EPDNEW
RGD ID:6828226
Promoter ID:MM_KWN:23365
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000102678
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361736,169,341 - 36,169,841 (-)MPROMDB
RGD ID:6850384
Promoter ID:EP17095
Type:single initiation site
Name:MM_HA15
Description:Class I transplantation antigens of major histocompatibilitycomplex, H2-T23 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:ubiquitous
Experiment Methods:Sequencing of a full-length cDNA; Primer extension with homologous sequence ladder
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv371736,169,646 - 36,169,706EPD
MGSCv361736,169,646 - 36,169,706EPD

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95957 AgrOrtholog
Ensembl Genes ENSMUSG00000067212 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000102678 ENTREZGENE
  ENSMUST00000102678.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15040 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95957 ENTREZGENE
NCBI Gene 15040 ENTREZGENE
PANTHER H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen H2-T23 PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A7VMS5_MOUSE UniProtKB/TrEMBL
  HA15_MOUSE UniProtKB/Swiss-Prot
  O98032 ENTREZGENE, UniProtKB/TrEMBL
  P06339 ENTREZGENE
  Q31153_MOUSE UniProtKB/TrEMBL
  Q3V014 ENTREZGENE, UniProtKB/TrEMBL
  Q4FZH9_MOUSE UniProtKB/TrEMBL
  Q9TQB1_MOUSE UniProtKB/TrEMBL
  Q9TQL9_MOUSE UniProtKB/TrEMBL
  Q9TQM0_MOUSE UniProtKB/TrEMBL
  Q9TQM1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9QYQ4 UniProtKB/TrEMBL