Oxa1l (oxidase assembly 1-like) - Rat Genome Database

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Gene: Oxa1l (oxidase assembly 1-like) Mus musculus
Analyze
Symbol: Oxa1l
Name: oxidase assembly 1-like
RGD ID: 1316769
MGI Page MGI
Description: Predicted to enable membrane insertase activity; mitochondrial ribosome binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including mitochondrial protein quality control; mitochondrion organization; and protein tetramerization. Located in mitochondrial inner membrane. Orthologous to human OXA1L (OXA1L mitochondrial inner membrane protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810020M02Rik; AI894287; mitochondrial inner membrane protein OXA1L; OXA1-like protein; oxidase assembly 1-like protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,598,298 - 54,607,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,598,291 - 54,607,130 (+)EnsemblGRCm39 Ensembl
GRCm381454,360,841 - 54,369,669 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,360,834 - 54,369,673 (+)EnsemblGRCm38mm10GRCm38
MGSCv371454,980,525 - 54,989,353 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,315,893 - 53,324,721 (+)NCBIMGSCv36mm8
Celera1452,150,627 - 52,160,108 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, etal., Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12865426   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18614015  
PMID:18799693   PMID:19501082   PMID:21873635   PMID:30550785   PMID:32325033   PMID:38355793  


Genomics

Comparative Map Data
Oxa1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,598,298 - 54,607,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,598,291 - 54,607,130 (+)EnsemblGRCm39 Ensembl
GRCm381454,360,841 - 54,369,669 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,360,834 - 54,369,673 (+)EnsemblGRCm38mm10GRCm38
MGSCv371454,980,525 - 54,989,353 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,315,893 - 53,324,721 (+)NCBIMGSCv36mm8
Celera1452,150,627 - 52,160,108 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.76NCBI
OXA1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,766,688 - 22,773,042 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,766,522 - 22,773,042 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,235,897 - 23,242,251 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,305,571 - 22,310,607 (+)NCBINCBI36Build 36hg18NCBI36
Build 341422,305,570 - 22,310,607NCBI
Celera143,098,625 - 3,103,892 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,353,072 - 3,358,342 (+)NCBIHuRef
CHM1_11423,234,451 - 23,239,721 (+)NCBICHM1_1
T2T-CHM13v2.01416,964,760 - 16,971,114 (+)NCBIT2T-CHM13v2.0
Oxa1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,783,725 - 31,791,353 (+)NCBIGRCr8
mRatBN7.21527,813,688 - 27,821,319 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,813,625 - 27,821,319 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,654,835 - 29,662,452 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,802,070 - 30,809,664 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,052,123 - 29,059,717 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,004,957 - 33,012,584 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,004,133 - 33,012,575 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,884,734 - 36,893,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,423,349 - 32,430,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1527,395,512 - 27,403,139 (+)NCBICelera
Cytogenetic Map15p13NCBI
Oxa1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,514,177 - 37,519,376 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,513,925 - 37,519,250 (-)NCBIChiLan1.0ChiLan1.0
OXA1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,196,383 - 24,201,523 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,412,869 - 23,418,009 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,584,220 - 3,589,360 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,683,984 - 21,689,101 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,683,983 - 21,689,101 (+)Ensemblpanpan1.1panPan2
OXA1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,108,669 - 3,132,337 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,108,757 - 3,132,334 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,057,344 - 3,081,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,215,543 - 3,239,277 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,215,606 - 3,239,862 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.182,908,165 - 2,931,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.082,969,507 - 2,993,191 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,231,605 - 3,255,317 (+)NCBIUU_Cfam_GSD_1.0
Oxa1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,860,267 - 34,865,069 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367221,524,116 - 1,528,659 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OXA1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,230,889 - 76,266,429 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,234,710 - 76,266,700 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,475,099 - 81,505,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OXA1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,131,273 - 23,137,470 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,131,453 - 23,137,245 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,285,299 - 23,291,375 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Oxa1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,757,840 - 9,763,640 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,757,615 - 9,763,686 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Oxa1l
323 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:465
Count of miRNA genes:337
Interacting mature miRNAs:392
Transcripts:ENSMUST00000000985
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4733525059962593Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse

Markers in Region
BB370826  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,368,433 - 54,368,548UniSTSGRCm38
MGSCv371454,988,117 - 54,988,232UniSTSGRCm37
Celera1452,158,872 - 52,158,987UniSTS
Cytogenetic Map14C2UniSTS
Whitehead/MRC_RH14615.39UniSTS
UniSTS:237182  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,361,643 - 54,361,875UniSTSGRCm38
MGSCv371454,981,327 - 54,981,559UniSTSGRCm37
Cytogenetic Map14C2UniSTS
AI894287  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,368,399 - 54,368,480UniSTSGRCm38
MGSCv371454,988,083 - 54,988,164UniSTSGRCm37
Celera1452,158,838 - 52,158,919UniSTS
Cytogenetic Map14C2UniSTS
Whitehead/MRC_RH14615.39UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC206013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000000985   ⟹   ENSMUSP00000000985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,598,298 - 54,607,130 (+)Ensembl
GRCm38.p6 Ensembl1454,360,841 - 54,369,673 (+)Ensembl
Ensembl Acc Id: ENSMUST00000196882
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,598,502 - 54,604,500 (+)Ensembl
GRCm38.p6 Ensembl1454,361,045 - 54,367,043 (+)Ensembl
Ensembl Acc Id: ENSMUST00000198107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,598,298 - 54,601,952 (+)Ensembl
GRCm38.p6 Ensembl1454,360,841 - 54,364,495 (+)Ensembl
Ensembl Acc Id: ENSMUST00000228567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,598,291 - 54,599,349 (+)Ensembl
GRCm38.p6 Ensembl1454,360,834 - 54,361,892 (+)Ensembl
Ensembl Acc Id: ENSMUST00000228719   ⟹   ENSMUSP00000153955
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,605,088 - 54,606,094 (+)Ensembl
GRCm38.p6 Ensembl1454,367,631 - 54,368,637 (+)Ensembl
RefSeq Acc Id: NM_026936   ⟹   NP_081212
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391454,598,298 - 54,607,130 (+)NCBI
GRCm381454,360,841 - 54,369,669 (+)ENTREZGENE
MGSCv371454,980,525 - 54,989,353 (+)RGD
Celera1452,150,627 - 52,160,108 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_081212   ⟸   NM_026936
- UniProtKB: Q8R091 (UniProtKB/Swiss-Prot),   Q8BK01 (UniProtKB/Swiss-Prot),   Q9D8X7 (UniProtKB/Swiss-Prot),   Q8BGA9 (UniProtKB/Swiss-Prot),   Q3UTE7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000000985   ⟸   ENSMUST00000000985
Ensembl Acc Id: ENSMUSP00000153955   ⟸   ENSMUST00000228719
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BGA9-F1-model_v2 AlphaFold Q8BGA9 1-433 view protein structure

Promoters
RGD ID:8682328
Promoter ID:EPDNEW_M19195
Type:multiple initiation site
Name:Oxa1l_1
Description:Mus musculus oxidase assembly 1-like , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381454,360,841 - 54,360,901EPDNEW
RGD ID:6825240
Promoter ID:MM_KWN:16865
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_026936,   UC007TVT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361454,980,356 - 54,980,856 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916339 AgrOrtholog
Ensembl Genes ENSMUSG00000000959 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000000985 ENTREZGENE
  ENSMUST00000000985.7 UniProtKB/Swiss-Prot
  ENSMUST00000228719.2 UniProtKB/TrEMBL
InterPro Membr_insert_YidC/Oxa1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YidC/ALB3/OXA1/COX18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69089 UniProtKB/Swiss-Prot
MGD MGI:1916339 ENTREZGENE
NCBI Gene 69089 ENTREZGENE
PANTHER MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12428 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 60KD_IMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Oxa1l PhenoGen
UniProt A0A2I3BQ74_MOUSE UniProtKB/TrEMBL
  OXA1L_MOUSE UniProtKB/Swiss-Prot
  Q3TC56_MOUSE UniProtKB/TrEMBL
  Q3TR38_MOUSE UniProtKB/TrEMBL
  Q3U3X8_MOUSE UniProtKB/TrEMBL
  Q3UTE7 ENTREZGENE, UniProtKB/TrEMBL
  Q8BGA9 ENTREZGENE
  Q8BK01 ENTREZGENE
  Q8R091 ENTREZGENE
  Q9D8X7 ENTREZGENE
UniProt Secondary Q8BK01 UniProtKB/Swiss-Prot
  Q8R091 UniProtKB/Swiss-Prot
  Q9D8X7 UniProtKB/Swiss-Prot