Babam1 (BRISC and BRCA1 A complex member 1) - Rat Genome Database
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Gene: Babam1 (BRISC and BRCA1 A complex member 1) Mus musculus
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Symbol: Babam1
Name: BRISC and BRCA1 A complex member 1
RGD ID: 1619174
MGI Page MGI
Description: Involved in hematopoietic stem cell proliferation. Predicted to localize to cytosol and nucleus. Orthologous to human BABAM1 (BRISC and BRCA1 A complex member 1); INTERACTS WITH sodium fluoride; 3,4-methylenedioxymethamphetamine (ortholog); arsenous acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430437P03Rik; BRCA1-A complex subunit MERIT40; BRISC and BRCA1-A complex member 1; mediator of RAP80 interactions and targeting subunit of 40 kDa; Merit40; new component of the BRCA1-A complex
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,848,809 - 71,857,416 (+)NCBIGRCm39mm39
GRCm38871,396,165 - 71,404,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,396,861 - 71,404,619 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,920,754 - 73,928,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv36874,325,857 - 74,333,534 (+)NCBImm8
Celera873,921,564 - 73,929,453 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:21267068   PMID:25636339   PMID:26338419   PMID:28190767   PMID:29676259   PMID:30755420   PMID:32325033  


Genomics

Comparative Map Data
Babam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,848,809 - 71,857,416 (+)NCBIGRCm39mm39
GRCm38871,396,165 - 71,404,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,396,861 - 71,404,619 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,920,754 - 73,928,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv36874,325,857 - 74,333,534 (+)NCBImm8
Celera873,921,564 - 73,929,453 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
BABAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1917,267,376 - 17,281,249 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1917,267,418 - 17,282,966 (+)EnsemblGRCh38hg38GRCh38
GRCh381917,267,443 - 17,279,337 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371917,378,200 - 17,390,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,239,232 - 17,251,162 (+)NCBINCBI36hg18NCBI36
Celera1917,279,989 - 17,291,905 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1916,945,293 - 16,956,825 (+)NCBIHuRef
CHM1_11917,377,658 - 17,389,627 (+)NCBICHM1_1
Babam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01619,792,720 - 19,798,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,792,838 - 19,798,894 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,652,945 - 19,659,019 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,558,063 - 18,564,094 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,558,060 - 18,564,091 (+)NCBI
Celera1618,274,474 - 18,280,505 (+)NCBICelera
Cytogenetic Map16p14NCBI
Babam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955524937,815 - 944,456 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955524939,250 - 944,457 (-)NCBIChiLan1.0ChiLan1.0
BABAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11917,729,538 - 17,742,447 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1917,729,568 - 17,742,447 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01916,755,518 - 16,767,634 (+)NCBIMhudiblu_PPA_v0panPan3
BABAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2045,466,805 - 45,473,009 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12045,466,808 - 45,474,953 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Babam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365963,574,507 - 3,582,370 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BABAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl260,398,191 - 60,407,557 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1260,398,170 - 60,407,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BABAM1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl615,775,229 - 15,786,822 (+)Ensembl
ChlSab1.1615,775,344 - 15,786,715 (+)NCBI
Babam1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908654,886 - 660,589 (-)NCBI

Position Markers
STS-D80227  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38871,403,459 - 71,404,684UniSTSGRCm38
GRCm38138,214,357 - 38,214,524UniSTSGRCm38
MGSCv37873,927,358 - 73,928,583UniSTSGRCm37
MGSCv37138,271,202 - 38,271,369UniSTSGRCm37
Celera137,990,066 - 37,990,233UniSTS
Celera873,928,140 - 73,929,365UniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map1BUniSTS
cM Map118.7UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:113
Interacting mature miRNAs:120
Transcripts:ENSMUST00000002473
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000002473   ⟹   ENSMUSP00000002473
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,396,861 - 71,404,619 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212087
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,402,784 - 71,403,332 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,402,222 - 71,403,028 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212769   ⟹   ENSMUSP00000148639
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,399,526 - 71,399,956 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213093
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,398,422 - 71,399,994 (+)Ensembl
RefSeq Acc Id: NM_026636   ⟹   NP_080912
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,849,499 - 71,857,416 (+)NCBI
GRCm38871,396,855 - 71,404,772 (+)NCBI
MGSCv37873,920,754 - 73,928,671 (+)RGD
Celera873,921,564 - 73,929,453 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242323   ⟹   XP_011240625
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,849,473 - 71,853,616 (+)NCBI
GRCm38871,396,165 - 71,400,972 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017312947   ⟹   XP_017168436
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,848,809 - 71,857,195 (+)NCBI
GRCm38871,396,165 - 71,404,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017312948   ⟹   XP_017168437
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,849,489 - 71,857,195 (+)NCBI
GRCm38871,396,841 - 71,404,551 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080912   ⟸   NM_026636
- UniProtKB: Q3UI43 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011240625   ⟸   XM_011242323
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017168436   ⟸   XM_017312947
- Peptide Label: isoform X1
- UniProtKB: Q3UI43 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017168437   ⟸   XM_017312948
- Peptide Label: isoform X1
- UniProtKB: Q3UI43 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000002473   ⟸   ENSMUST00000002473
RefSeq Acc Id: ENSMUSP00000148639   ⟸   ENSMUST00000212769

Promoters
RGD ID:8667389
Promoter ID:EPDNEW_M11726
Type:multiple initiation site
Name:Babam1_1
Description:Mus musculus BRISC and BRCA1 A complex member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38871,396,877 - 71,396,937EPDNEW
RGD ID:6842547
Promoter ID:MM_KWN:54779
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_026636
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36873,919,786 - 73,920,872 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915501 AgrOrtholog
Ensembl Genes ENSMUSG00000031820 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000002473 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148639 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000002473 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000212769 UniProtKB/TrEMBL
InterPro BABAM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:68251 UniProtKB/Swiss-Prot
MGD MGI:1915501 ENTREZGENE
NCBI Gene 68251 ENTREZGENE
PANTHER PTHR15660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Babam1 PhenoGen
Superfamily-SCOP SSF53300 UniProtKB/Swiss-Prot
UniGene Mm.21749 ENTREZGENE
UniProt A0A1D5RM60_MOUSE UniProtKB/TrEMBL
  BABA1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8C5Q8 UniProtKB/Swiss-Prot
  Q99JU2 UniProtKB/Swiss-Prot
  Q9CTJ4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-19 Babam1  BRISC and BRCA1 A complex member 1  5430437P03Rik  RIKEN cDNA 5430437P03 gene  Symbol and/or name change 5135510 APPROVED