Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CLEC14A mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of CLEC14A mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of CLEC14A mRNA | CTD | PMID:16214954 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CLEC14A mRNA | CTD | PMID:21215274 and PMID:21724226 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CLEC14A mRNA | CTD | PMID:22298810 and PMID:34747641 | 3,7-dihydropurine-6-thione | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of CLEC14A mRNA | CTD | PMID:23358152 | 4,4'-sulfonyldiphenol | increases methylation | EXP | | 6480464 | bisphenol S results in increased methylation of CLEC14A promoter | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of CLEC14A mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of CLEC14A mRNA | CTD | PMID:24780913 and PMID:25825206 | 6-propyl-2-thiouracil | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of CLEC14A mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | acetamide results in increased expression of CLEC14A mRNA | CTD | PMID:31881176 | aconitine | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Aconitine results in increased expression of CLEC14A protein | CTD | PMID:33236894 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CLEC14A mRNA | CTD | PMID:30807115 | aflatoxin B1 | decreases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CLEC14A gene | CTD | PMID:27153756 | amitrole | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of CLEC14A mRNA | CTD | PMID:30047161 | antirheumatic drug | increases expression | ISO | CLEC14A (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CLEC14A mRNA | CTD | PMID:24449571 | arsenite(3-) | increases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | arsenite results in increased methylation of CLEC14A promoter | CTD | PMID:23974009 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of CLEC14A mRNA | CTD | PMID:21569818 | benzo[a]pyrene | increases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CLEC14A exon | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | EXP | | 6480464 | benzo(b)fluoranthene results in decreased expression of CLEC14A mRNA | CTD | PMID:26377693 | bisphenol A | affects expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of CLEC14A mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CLEC14A mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | CLEC14A (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CLEC14A mRNA | CTD | PMID:29275510 | bisphenol A | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of CLEC14A mRNA | CTD | PMID:30816183 more ... | carbon nanotube | affects expression | EXP | | 6480464 | Nanotubes and Carbon affects the expression of CLEC14A mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of CLEC14A mRNA | CTD | PMID:25620056 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of CLEC14A mRNA | CTD | PMID:25554681 and PMID:25620056 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of CLEC14A mRNA | CTD | PMID:37019170 | cobalt dichloride | decreases expression | ISO | CLEC14A (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of CLEC14A mRNA | CTD | PMID:19320972 | endosulfan | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of CLEC14A mRNA | CTD | PMID:29391264 | fipronil | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | fipronil results in increased expression of CLEC14A mRNA | CTD | PMID:31881178 | flutamide | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of CLEC14A mRNA | CTD | PMID:24136188 | fonofos | increases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | Fonofos results in increased methylation of CLEC14A promoter | CTD | PMID:22847954 | levofloxacin | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Levofloxacin results in increased expression of CLEC14A mRNA | CTD | PMID:24136188 | mercaptopurine | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of CLEC14A mRNA | CTD | PMID:23358152 | oxaliplatin | multiple interactions | ISO | Clec14a (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CLEC14A mRNA | CTD | PMID:25729387 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CLEC14A mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of CLEC14A mRNA | CTD | PMID:27106289 and PMID:34911549 | parathion | increases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | Parathion results in increased methylation of CLEC14A promoter | CTD | PMID:22847954 | phenethyl isothiocyanate | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | phenethyl isothiocyanate results in increased expression of CLEC14A mRNA | CTD | PMID:17616710 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of CLEC14A mRNA | CTD | PMID:23091169 | pioglitazone | multiple interactions | EXP | | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLEC14A mRNA | CTD | PMID:27935865 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of CLEC14A mRNA | CTD | PMID:18445702 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CLEC14A mRNA | CTD | PMID:23811191 | poly(I:C) | multiple interactions | ISO | Clec14a (Rattus norvegicus) | 6480464 | [Poly I-C co-treated with HU 211] results in increased expression of CLEC14A mRNA | CTD | PMID:26923065 | propiconazole | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | propiconazole results in increased expression of CLEC14A mRNA | CTD | PMID:30047161 | purine-6-thiol | decreases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of CLEC14A mRNA | CTD | PMID:23358152 | sulfadimethoxine | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of CLEC14A mRNA | CTD | PMID:30047161 | terbufos | increases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | terbufos results in increased methylation of CLEC14A promoter | CTD | PMID:22847954 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of CLEC14A mRNA | CTD | PMID:17484886 | titanium dioxide | affects expression | EXP | | 6480464 | titanium dioxide affects the expression of CLEC14A mRNA | CTD | PMID:23557971 | topotecan | multiple interactions | ISO | Clec14a (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CLEC14A mRNA | CTD | PMID:25729387 | tremolite asbestos | decreases expression | EXP | | 6480464 | tremolite results in decreased expression of CLEC14A mRNA | CTD | PMID:29279043 | triadimefon | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | triadimefon results in increased expression of CLEC14A mRNA | CTD | PMID:30047161 | troglitazone | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | troglitazone results in increased expression of CLEC14A mRNA | CTD | PMID:21515302 | valdecoxib | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of CLEC14A mRNA | CTD | PMID:24136188 | valproic acid | decreases methylation | ISO | CLEC14A (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CLEC14A gene | CTD | PMID:29154799 | vinclozolin | affects expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of CLEC14A mRNA | CTD | PMID:19015723 | vinclozolin | increases expression | ISO | Clec14a (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of CLEC14A mRNA | CTD | PMID:20566332 | |