Cope (coatomer protein complex, subunit epsilon)

Gene: Cope (coatomer protein complex, subunit epsilon) Mus musculus

Analyze

Symbol:

Cope

Name:

coatomer protein complex, subunit epsilon

RGD ID:

1315599

MGI Page

MGI

Description:

Predicted to enable structural molecule activity. Acts upstream of or within protein localization to axon. Located in COPI-coated vesicle. Is expressed in cerebral cortex. Orthologous to human COPE (COPI coat complex subunit epsilon).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1110005D17Rik; coatomer subunit epsilon; Cop; Cope1; epsilon-coat protein; epsilon-COP; nonclathrin coat protein epsilon-COP

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COPE (COPI coat complex subunit epsilon)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Cope (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cope (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	COPE (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COPE (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cope (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COPE (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COPE (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cope (COPI coat complex subunit epsilon)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Cope (COPI coat complex subunit epsilon)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	COPE (COPI coat complex subunit epsilon)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cope (coatomer protein complex, subunit epsilon)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SEC28	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	cope-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	epsilonCOP	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cope	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Related Pseudogenes:

Gm4857

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,755,417 - 70,765,652 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	70,755,168 - 70,765,643 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	70,302,767 - 70,313,002 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,302,518 - 70,312,993 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	72,826,684 - 72,836,889 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	73,231,774 - 73,241,979 (+)	NCBI		MGSCv36	mm8
Celera	8	72,859,282 - 72,869,463 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ISO)

progressive myoclonus epilepsy 8 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (EXP)

1,2-dimethylhydrazine (EXP)

1-chloro-2,4-dinitrobenzene (ISO)

14-Deoxy-11,12-didehydroandrographolide (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4,6-trinitrotoluene (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

aconitine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

bisphenol F (ISO)

bufalin (ISO)

butan-1-ol (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (EXP)

chlorpyrifos (EXP)

chrysene (EXP)

clobetasol (EXP)

clofibrate (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin (ISO)

crocidolite asbestos (EXP)

cyclosporin A (ISO)

elemental selenium (ISO)

endosulfan (ISO)

fipronil (ISO)

flutamide (ISO)

folic acid (EXP)

FR900359 (ISO)

glafenine (ISO)

hydralazine (ISO)

ivermectin (ISO)

maneb (EXP)

methidathion (EXP)

nefazodone (ISO)

paclitaxel (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (EXP)

quercetin (ISO)

resveratrol (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

tamoxifen (EXP)

tert-butyl hydroperoxide (ISO)

testosterone (EXP,ISO)

tetrachloroethene (EXP)

tetrachloromethane (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum to Golgi vesicle-mediated transport (IBA)

intra-Golgi vesicle-mediated transport (IBA)

protein localization to axon (IMP)

protein transport (IEA)

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (IEA)

vesicle-mediated transport (IEA)

Cellular Component

COPI vesicle coat (IBA)

COPI-coated vesicle (IDA)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

Golgi apparatus (ISO)

membrane (IEA)

nucleoplasm (ISO)

Molecular Function

protein binding (IPI)

structural molecule activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:9798653	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11353399	PMID:12477932	PMID:14610273	PMID:14645249	PMID:15489334	PMID:15782199
PMID:16141072	PMID:16141073	PMID:16602821	PMID:16919471	PMID:21267068	PMID:21300694	PMID:21677750	PMID:21873635	PMID:26206133	PMID:27113764	PMID:28378742	PMID:30457570
PMID:32325033

Genomics

Comparative Map Data

Cope
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,755,417 - 70,765,652 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	70,755,168 - 70,765,643 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	70,302,767 - 70,313,002 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,302,518 - 70,312,993 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	72,826,684 - 72,836,889 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	73,231,774 - 73,241,979 (+)	NCBI		MGSCv36	mm8
Celera	8	72,859,282 - 72,869,463 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

COPE
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	18,899,514 - 18,919,387 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	18,899,514 - 18,919,387 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	19,010,323 - 19,030,196 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	18,871,323 - 18,891,199 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	18,871,322 - 18,891,199	NCBI
Celera	19	18,915,147 - 18,935,023 (-)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	18,574,751 - 18,594,613 (-)	NCBI		HuRef
CHM1_1	19	19,009,997 - 19,029,866 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	19,035,138 - 19,055,145 (-)	NCBI		T2T-CHM13v2.0

Cope
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	19,148,832 - 19,159,052 (-)	NCBI		GRCr8
mRatBN7.2	16	19,114,871 - 19,125,076 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	19,114,871 - 19,128,907 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	19,154,662 - 19,164,872 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,287,172 - 20,297,391 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,207,623 - 19,217,833 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	20,863,141 - 20,873,516 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,863,141 - 20,873,521 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	20,714,916 - 20,725,283 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	19,602,842 - 19,609,515 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	19,598,764 - 19,609,319 (-)	NCBI
Celera	16	19,308,848 - 19,315,509 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Cope
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	2,767,997 - 2,779,671 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	2,767,996 - 2,779,671 (+)	NCBI	ChiLan1.0	ChiLan1.0

COPE
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	23,761,008 - 23,780,688 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	22,767,216 - 22,787,079 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	18,337,678 - 18,357,399 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	19,345,680 - 19,364,737 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	19,345,680 - 19,364,737 (-)	Ensembl	panpan1.1		panPan2

COPE
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	44,195,198 - 44,211,613 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	44,195,231 - 44,211,617 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	44,110,594 - 44,127,011 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	44,682,117 - 44,698,534 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	44,682,162 - 44,698,494 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	43,919,406 - 43,935,822 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	44,329,615 - 44,346,030 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	44,605,077 - 44,621,505 (+)	NCBI		UU_Cfam_GSD_1.0

Cope
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	202,873,846 - 202,890,428 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	2,422,947 - 2,439,749 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	2,422,988 - 2,439,567 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COPE
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	58,930,931 - 58,948,469 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	58,930,929 - 58,948,466 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	58,729,731 - 58,747,267 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COPE
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	17,354,926 - 17,375,935 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	17,354,508 - 17,375,922 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	1,948,377 - 1,968,852 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cope
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	1,951,403 - 1,963,459 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624908	1,951,845 - 1,963,474 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cope
233 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1292
Count of miRNA genes:	581
Interacting mature miRNAs:	688
Transcripts:	ENSMUST00000066469, ENSMUST00000128003, ENSMUST00000128822, ENSMUST00000134822, ENSMUST00000140363, ENSMUST00000150968, ENSMUST00000167850, ENSMUST00000168018
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558870	Eae36_m	experimental allergic encephalomyelitis susceptibility 36 (mouse)			Not determined		8	14773160	71498244	Mouse
1357811	Orq3_m	ovulation rate QTL 3 (mouse)			Not determined		8	32506572	71740637	Mouse
4140966	Egq12_m	early growth QTL 12 (mouse)			Not determined			32506572	71740637	Mouse
4141437	W10q14_m	weight 10 weeks QTL 14 (mouse)			Not determined			32506572	71740637	Mouse
4141172	W6q9_m	weight 6 weeks QTL 9 (mouse)			Not determined			32506572	71740637	Mouse
4140967	Bmd39_m	bone mineral density 39 (mouse)			Not determined		8	32506572	117965439	Mouse
1558875	Eae31_m	experimental allergic encephalomyelitis susceptibility 31 (mouse)			Not determined		8	35109930	115563747	Mouse
1301013	Capsq4_m	capsaicin sensitivity related QTL 4 (mouse)			Not determined		8	36630154	93455280	Mouse
27226754	Femd6_m	femur midshaft diameter 6, 10 week (mouse)					8	37867154	110326632	Mouse
12904744	Carcdq1_m	cardiac collagen deposition QTL 1 (mouse)					8	40162297	95416226	Mouse
1301544	Iba3_m	induction of brown adipocytes 3 (mouse)			Not determined		8	44747914	78748059	Mouse
10766453	Char11_m	P. chabaudi malaria resistance QTL 11 (mouse)					8	48090064	82090180	Mouse
1301717	Adip4_m	adiposity 4 (mouse)			Not determined		8	48090064	82090180	Mouse
1301441	Skull11_m	skull morphology 11 (mouse)			Not determined		8	48190168	82190288	Mouse
1357715	Alaa3_m	alopecia areata 3 (mouse)			Not determined		8	49245591	83245673	Mouse
14746987	Manh64_m	mandible shape 64 (mouse)					8	50505958	84505958	Mouse
14747005	Mancz7_m	mandible centroid size 7 (mouse)					8	50505958	84505958	Mouse
14700686	Civq3_m	cerebral infarct volume QTL 3 (mouse)					8	52334843	86334843	Mouse
1301506	Aevm1_m	autoimmune extremity vasculitis in MRL mice 1 (mouse)			Not determined		8	54740461	88740637	Mouse
1301952	Im3_m	immunoregulatory 3 (mouse)			Not determined		8	55159258	89159407	Mouse
10412287	Carg3_m	Candida albicans resistance gene 3 (mouse)			Not determined		8	56298872	90298872	Mouse
11353828	Gf7_m	gonadal fat pad weight 7 (mouse)					8	58928107	92928107	Mouse
10043975	Obq31_m	obesity QTL 31 (mouse)			Not determined		8	59136404	93136404	Mouse
1301688	Orch6_m	autoimmune orchitis resistance 6 (mouse)			Not determined		8	61513479	95513605	Mouse
4141285	Tgq18_m	triglyceride QTL 18 (mouse)			Not determined			64186736	98186736	Mouse
4141797	Skmw16_m	skeletal muscle weight 16 (mouse)			Not determined		8	64666176	98666325	Mouse
11039503	Ccc4_m	colitis susceptibility in the Collaborative Cross 4 (mouse)					8	65174237	78002730	Mouse
1357787	Vtbt5_m	vertebral trabecular bone trait 5 (mouse)			Not determined		8	66084397	100084549	Mouse
10043992	Hbnr11_m	Heligmosomoides bakeri nematode resistance 11 (mouse)			Not determined		8	66326836	100326976	Mouse
10766466	Char12_m	P. chabaudi malaria resistance QTL 12 (mouse)					8	68722479	83326976	Mouse

Markers in Region

RH118314

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	70,303,360 - 70,303,538	UniSTS	GRCm38
MGSCv37	8	72,827,259 - 72,827,437	UniSTS	GRCm37
Celera	8	72,859,857 - 72,860,035	UniSTS
Cytogenetic Map	8	B3.3	UniSTS
Whitehead/MRC_RH	8	740.57	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB039837	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC158553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK083279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK140753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK217937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC009170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC057328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HH768355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HH768393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U89427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000066469 ⟹ ENSMUSP00000071078

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,168 - 70,765,640 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,518 - 70,312,990 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000128003 ⟹ ENSMUSP00000122888

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,758,348 - 70,765,640 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,305,698 - 70,312,990 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000128822

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,443 - 70,759,572 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,793 - 70,306,922 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000134822

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,419 - 70,765,643 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,769 - 70,312,993 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000140363

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,391 - 70,759,067 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,741 - 70,306,417 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000150968 ⟹ ENSMUSP00000119055

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,423 - 70,763,141 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,773 - 70,310,491 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000167850 ⟹ ENSMUSP00000132976

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,761,157 - 70,765,640 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,308,507 - 70,312,990 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000168018 ⟹ ENSMUSP00000130416

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	70,755,446 - 70,765,422 (+)	Ensembl
GRCm38.p6 Ensembl	8	70,302,796 - 70,312,772 (+)	Ensembl

RefSeq Acc Id:

NM_021538 ⟹ NP_067513

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	70,755,417 - 70,765,652 (+)	NCBI
GRCm38	8	70,302,767 - 70,313,002 (+)	NCBI
MGSCv37	8	72,826,684 - 72,836,889 (+)	RGD
Celera	8	72,859,282 - 72,869,463 (+)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

CTACGTGTCCCAGAAGAAGGTTGGTTAGAGGTGCGGTGACATGGCTCCTCCGGTTCCTGGCGCG
GTCTCTGGCGGCTCCGGAGAGGTAGATGAGCTGTTCGACGTGAAGAACGCTTTCTACATCGGCA
GCTACCAGCAGTGCATCAACGAGGCTCAGCGCGTGAAGCTCTCCAGTCCTGAGCGGGAAGTAGA
GAGGGATGTCTTCCTATACAGAGCATACCTCGCACAGAGGAAGTATGGCGTGGTCCTGGATGAG
ATCAAACCCTCCTCGGCCCCAGAACTCCAGGCTGTGCGCATGTTTGCTGAGTACCTTGCCAGTG
AGAACCAGAGGGACAGCATCGTGCTGGAGCTGGATCGGGAGATGAGCAGGAGTGTGGATGTGAC
CAATACCACTTTCCTGCTCATGGCTGCCTCCATCTACTTCCACGACCAGAACCCGGATGCAGCC
CTGCGAACCCTGCACCAGGGCGACGGCCTTGAGTGCATGGCCATGACGATTCAGATCCTCCTCA
AGCTGGACAGGCTGGACCTAGCCCGGAAGGAGCTGAAGAAGATGCAGGACCAAGATGAGGACGC
CACCCTTACCCAGCTAGCCACTGCCTGGGTCAACCTGGCTGTGGGTGGTGAGAAGCTACAAGAA
GCCTACTACATATTCCAAGAGCTGGCCGACAAGTGCTCCCCCACACTGCTGCTGCTCAATGGCC
AGGCAGCCTGCCACTCAGCACAGGGCCGCTGGGAGACTGCAGAGGGTGTGCTGCAAGAGGCACT
GGACAAGGACAGCGGCCACCCTGAGACCCTCATCAATCTCATTGTACTGTCACAGCACCTGGGC
AAGCCCCCTGAGGTGACAAACCGATACTTGTCACAGCTGAAGGATGCACACAGGGCCCACCCCT
TCATCAAGGAGTACCAGGCCAAGGAGAACGATTTCGATCGCCTGGCAATGCAGTATGCGCCCAG
TGCTTAAAGTGGAGATGCCCTGGTGACCCCAACTGTGTGCCGCGGGATGCTGTCCTCCCTTTGT
GTCTGCCAATAAAGTCTATCCATTATCGCTCTGCCTGAT

hide sequence

Protein Sequences


Protein RefSeqs	NP_067513	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC36533	(Get FASTA)	NCBI Sequence Viewer
	AAH09170	(Get FASTA)	NCBI Sequence Viewer
	AAH83336	(Get FASTA)	NCBI Sequence Viewer
	BAA92384	(Get FASTA)	NCBI Sequence Viewer
	BAB22801	(Get FASTA)	NCBI Sequence Viewer
	CBX84923	(Get FASTA)	NCBI Sequence Viewer
	CBX84942	(Get FASTA)	NCBI Sequence Viewer
	EDL28808	(Get FASTA)	NCBI Sequence Viewer
	EDL28809	(Get FASTA)	NCBI Sequence Viewer
	EDL28810	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000071078
	ENSMUSP00000071078.8
	ENSMUSP00000119055.2
	ENSMUSP00000122888.2
	ENSMUSP00000130416.2
	ENSMUSP00000132976.2
GenBank Protein	O89079	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_067513 ⟸ NM_021538

- UniProtKB:

Q9JM65 (UniProtKB/Swiss-Prot), O89079 (UniProtKB/Swiss-Prot), Q9D1J2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPPVPGAVSGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQR
KYGVVLDEIKPSSAPELQAVRMFAEYLASENQRDSIVLELDREMSRSVDVTNTTFLLMAASIYF
HDQNPDAALRTLHQGDGLECMAMTIQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVNLA
VGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINL
IVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRLAMQYAPSA

hide sequence

RefSeq Acc Id:

ENSMUSP00000119055 ⟸ ENSMUST00000150968

RefSeq Acc Id:

ENSMUSP00000071078 ⟸ ENSMUST00000066469

RefSeq Acc Id:

ENSMUSP00000130416 ⟸ ENSMUST00000168018

RefSeq Acc Id:

ENSMUSP00000122888 ⟸ ENSMUST00000128003

RefSeq Acc Id:

ENSMUSP00000132976 ⟸ ENSMUST00000167850

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O89079-F1-model_v2	AlphaFold	O89079	1-308	view protein structure

Promoters

RGD ID:

8667299

Promoter ID:

EPDNEW_M11680

Type:

initiation region

Name:

Cope_1

Description:

Mus musculus coatomer protein complex, subunit epsilon , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	70,302,778 - 70,302,838	EPDNEW

RGD ID:

6843053

Promoter ID:

MM_KWN:54693

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000067558, OTTMUST00000067559, OTTMUST00000067561, OTTMUST00000067562, OTTMUST00000067565, OTTMUST00000067566, OTTMUST00000067567, OTTMUST00000067568, UC009LZW.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	72,826,274 - 72,826,774 (-)	MPROMDB

RGD ID:

6842962

Promoter ID:

MM_KWN:54694

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, Brain, Kidney

Transcripts:

OTTMUST00000067563

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	72,829,111 - 72,829,611 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1891702	AgrOrtholog
Ensembl Genes	ENSMUSG00000055681	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000066469	ENTREZGENE
	ENSMUST00000066469.14	UniProtKB/Swiss-Prot
	ENSMUST00000128003.8	UniProtKB/TrEMBL
	ENSMUST00000150968.8	UniProtKB/TrEMBL
	ENSMUST00000167850.3	UniProtKB/TrEMBL
	ENSMUST00000168018.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Coatomer_esu	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:59042	UniProtKB/Swiss-Prot
MGD	MGI:1891702	ENTREZGENE
NCBI Gene	59042	ENTREZGENE
PANTHER	COATOMER SUBUNIT EPSILON	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10805	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Coatomer_E	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cope	PhenoGen
PIRSF	Coatomer_esu	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	COPE_MOUSE	UniProtKB/Swiss-Prot
	D3Z315_MOUSE	UniProtKB/TrEMBL
	E9Q6I5_MOUSE	UniProtKB/TrEMBL
	F6XIG5_MOUSE	UniProtKB/TrEMBL
	F6YFR7_MOUSE	UniProtKB/TrEMBL
	O89079	ENTREZGENE
	Q9D1J2	ENTREZGENE, UniProtKB/TrEMBL
	Q9JM65	ENTREZGENE
UniProt Secondary	Q9JM65	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar