Dhrs7c (dehydrogenase/reductase (SDR family) member 7C) - Rat Genome Database

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Gene: Dhrs7c (dehydrogenase/reductase (SDR family) member 7C) Mus musculus
Analyze
Symbol: Dhrs7c
Name: dehydrogenase/reductase (SDR family) member 7C
RGD ID: 1315918
MGI Page MGI
Description: Enables NAD-retinol dehydrogenase activity. Involved in cellular calcium ion homeostasis and glucose import. Acts upstream of or within regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Located in longitudinal sarcoplasmic reticulum and sarcoplasmic reticulum membrane. Orthologous to human DHRS7C (dehydrogenase/reductase 7C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110001P11Rik; AI120487; dehydrogenase/reductase SDR family member 7C; RP23-338M9.5; sarcoplasmic reticulum protein of 35 kDa; short-chain dehydrogenase/reductase family 32C member 2; SRP-35
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,689,097 - 67,706,828 (+)NCBIGRCm39mm39
GRCm39 Ensembl1167,689,013 - 67,706,828 (+)Ensembl
GRCm381167,798,271 - 67,816,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,798,187 - 67,816,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,611,773 - 67,629,504 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,614,483 - 67,632,200 (+)NCBImm8
Celera1174,742,016 - 74,759,751 (+)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:21995425   PMID:22143674   PMID:27806939   PMID:29330505  


Genomics

Comparative Map Data
Dhrs7c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,689,097 - 67,706,828 (+)NCBIGRCm39mm39
GRCm39 Ensembl1167,689,013 - 67,706,828 (+)Ensembl
GRCm381167,798,271 - 67,816,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,798,187 - 67,816,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,611,773 - 67,629,504 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,614,483 - 67,632,200 (+)NCBImm8
Celera1174,742,016 - 74,759,751 (+)NCBICelera
Cytogenetic Map11B3NCBI
DHRS7C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38179,771,438 - 9,791,592 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl179,771,434 - 9,791,592 (-)EnsemblGRCh38hg38GRCh38
GRCh37179,674,755 - 9,694,909 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36179,615,480 - 9,635,326 (-)NCBINCBI36hg18NCBI36
Celera179,707,201 - 9,727,047 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef179,575,182 - 9,595,046 (-)NCBIHuRef
CHM1_1179,684,765 - 9,704,628 (-)NCBICHM1_1
T2T-CHM13v2.0179,679,162 - 9,699,310 (-)NCBI
Dhrs7c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21052,495,262 - 52,513,338 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1052,495,262 - 52,513,338 (+)Ensembl
Rnor_6.01054,352,270 - 54,370,653 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1054,352,270 - 54,370,653 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01054,098,500 - 54,116,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41054,518,094 - 54,536,171 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11054,531,747 - 54,549,796 (+)NCBI
Celera1051,675,569 - 51,693,645 (+)NCBICelera
Cytogenetic Map10q24NCBI
Dhrs7c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554677,330,188 - 7,342,053 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554677,330,267 - 7,341,897 (+)NCBIChiLan1.0ChiLan1.0
DHRS7C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11746,608,656 - 46,628,709 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1746,608,656 - 46,628,709 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01741,864,761 - 41,884,938 (+)NCBIMhudiblu_PPA_v0panPan3
DHRS7C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1534,224,699 - 34,239,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl534,224,700 - 34,239,798 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha534,360,745 - 34,375,901 (-)NCBI
ROS_Cfam_1.0534,328,723 - 34,343,881 (-)NCBI
ROS_Cfam_1.0 Ensembl534,328,725 - 34,343,822 (-)Ensembl
UMICH_Zoey_3.1534,294,553 - 34,309,712 (-)NCBI
UNSW_CanFamBas_1.0534,252,649 - 34,267,793 (-)NCBI
UU_Cfam_GSD_1.0534,433,105 - 34,448,262 (-)NCBI
Dhrs7c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560249,257,918 - 49,277,926 (-)NCBI
SpeTri2.0NW_0049365952,732,106 - 2,769,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHRS7C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,639,773 - 54,661,662 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,647,773 - 54,661,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,405,743 - 57,419,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHRS7C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,111,538 - 9,132,553 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl169,111,957 - 9,132,355 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605912,209,865 - 12,230,268 (+)NCBIVero_WHO_p1.0
Dhrs7c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478612,222,248 - 12,236,301 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462478612,222,735 - 12,236,209 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI120487  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,800,895 - 67,801,027UniSTSGRCm38
MGSCv371167,614,397 - 67,614,529UniSTSGRCm37
Celera1174,744,637 - 74,744,769UniSTS
Cytogenetic Map11B3UniSTS
Whitehead/MRC_RH11882.27UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116304211368500330Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:938
Count of miRNA genes:518
Interacting mature miRNAs:622
Transcripts:ENSMUST00000040574, ENSMUST00000123862, ENSMUST00000135830, ENSMUST00000142686, ENSMUST00000149722, ENSMUST00000168612
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000123862
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,689,013 - 67,691,636 (+)Ensembl
GRCm38.p6 Ensembl1167,798,187 - 67,800,810 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135830
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,689,102 - 67,692,165 (+)Ensembl
GRCm38.p6 Ensembl1167,798,276 - 67,801,339 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142686
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,689,103 - 67,689,892 (+)Ensembl
GRCm38.p6 Ensembl1167,798,277 - 67,799,066 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149722
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,689,097 - 67,692,004 (+)Ensembl
GRCm38.p6 Ensembl1167,798,271 - 67,801,178 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168612   ⟹   ENSMUSP00000130924
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,689,113 - 67,706,828 (+)Ensembl
GRCm38.p6 Ensembl1167,798,287 - 67,816,002 (+)Ensembl
RefSeq Acc Id: NM_001013013   ⟹   NP_001013031
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,689,097 - 67,706,828 (+)NCBI
GRCm381167,798,271 - 67,816,002 (+)ENTREZGENE
MGSCv371167,611,773 - 67,629,504 (+)RGD
Celera1174,742,016 - 74,759,751 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001013031 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL10437 (Get FASTA)   NCBI Sequence Viewer  
  Q8CHS7 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001013031   ⟸   NM_001013013
- Peptide Label: precursor
- UniProtKB: Q8CHS7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000130924   ⟸   ENSMUST00000168612

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CHS7-F1-model_v2 AlphaFold Q8CHS7 1-311 view protein structure

Promoters
RGD ID:8675088
Promoter ID:EPDNEW_M15575
Type:multiple initiation site
Name:Dhrs7c_1
Description:Mus musculus dehydrogenase/reductase member 7C , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381167,798,276 - 67,798,336EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915710 AgrOrtholog
Ensembl Genes ENSMUSG00000033044 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000130924 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000168612 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report mmu:68460 UniProtKB/Swiss-Prot
MGD MGI:1915710 ENTREZGENE
NCBI Gene 68460 ENTREZGENE
Pfam adh_short UniProtKB/Swiss-Prot
PhenoGen Dhrs7c PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
  SDRFAMILY UniProtKB/Swiss-Prot
PROSITE ADH_SHORT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt DRS7C_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B1ATJ2 UniProtKB/Swiss-Prot