Dnajc30 (DnaJ heat shock protein family (Hsp40) member C30) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dnajc30 (DnaJ heat shock protein family (Hsp40) member C30) Mus musculus
Analyze
Symbol: Dnajc30
Name: DnaJ heat shock protein family (Hsp40) member C30
RGD ID: 1557907
MGI Page MGI
Description: Involved in brain development and regulation of mitochondrial ATP synthesis coupled proton transport. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human DNAJC30 (DnaJ heat shock protein family (Hsp40) member C30); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300007M11Rik; DnaJ (Hsp40) homolog, subfamily C, member 30; dnaJ homolog subfamily C member 30; dnaJ homolog subfamily C member 30, mitochondrial; Wbscr; Wbscr18; williams-Beuren syndrome chromosomal region 18 protein homolog; Williams-Beuren syndrome chromosome region 18 homolog; Williams-Beuren syndrome critical region 18
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm4839  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,093,060 - 135,094,219 (+)NCBIGRCm39mm39
GRCm385135,064,206 - 135,065,365 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,064,202 - 135,065,862 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,540,076 - 135,541,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv365135,348,833 - 135,349,992 (+)NCBImm8
Celera5132,074,535 - 132,075,694 (+)NCBICelera
Cytogenetic Map5G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11779826   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18614015   PMID:30318146  


Genomics

Comparative Map Data
Dnajc30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,093,060 - 135,094,219 (+)NCBIGRCm39mm39
GRCm385135,064,206 - 135,065,365 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,064,202 - 135,065,862 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,540,076 - 135,541,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv365135,348,833 - 135,349,992 (+)NCBImm8
Celera5132,074,535 - 132,075,694 (+)NCBICelera
Cytogenetic Map5G2NCBI
DNAJC30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl773,680,918 - 73,683,453 (-)EnsemblGRCh38hg38GRCh38
GRCh38773,680,918 - 73,683,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,095,248 - 73,097,781 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,733,184 - 72,735,717 (-)NCBINCBI36hg18NCBI36
Build 34772,539,898 - 72,542,432NCBI
Celera768,573,462 - 68,575,995 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef768,977,660 - 68,980,193 (-)NCBIHuRef
CHM1_1773,240,984 - 73,243,517 (-)NCBICHM1_1
CRA_TCAGchr7v2772,428,320 - 72,430,853 (-)NCBI
Dnajc30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01224,668,398 - 24,669,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,668,398 - 24,669,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,668,668 - 26,669,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,723,460 - 22,724,526 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1223,391,608 - 23,392,674 (-)NCBICelera
Cytogenetic Map12q12NCBI
Dnajc30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,057,620 - 14,058,303 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,057,517 - 14,058,729 (+)NCBIChiLan1.0ChiLan1.0
DNAJC30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1780,833,897 - 80,836,428 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,835,722 - 80,836,402 (-)Ensemblpanpan1.1panPan2
DNAJC30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl66,595,294 - 6,595,974 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.166,595,233 - 6,596,440 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dnajc30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365432,895,771 - 2,897,761 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJC30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1310,951,173 - 10,959,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,653,936 - 10,656,064 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJC30
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,383,068 - 9,385,590 (+)NCBI
ChlSab1.1 Ensembl289,383,095 - 9,383,775 (+)Ensembl
Dnajc30
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474014,131,362 - 14,133,580 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119806972141714711Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121457140151834684Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121556974151834684Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124714580151834684Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125101165141714711Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125147702151834684Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129583274151834684Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129851021151834684Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5134002093151834684Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:209
Count of miRNA genes:179
Interacting mature miRNAs:195
Transcripts:ENSMUST00000071263
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071263   ⟹   ENSMUSP00000094318
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5135,064,202 - 135,065,862 (+)Ensembl
RefSeq Acc Id: NM_025362   ⟹   NP_079638
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,093,060 - 135,094,219 (+)NCBI
GRCm385135,064,206 - 135,065,365 (+)ENTREZGENE
MGSCv375135,540,076 - 135,541,235 (+)RGD
Celera5132,074,535 - 132,075,694 (+)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079638   ⟸   NM_025362
- Peptide Label: precursor
- UniProtKB: P59041 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000094318   ⟸   ENSMUST00000071263
Protein Domains
J

Promoters
RGD ID:6888302
Promoter ID:EPDNEW_M7602
Type:multiple initiation site
Name:Dnajc30_1
Description:Mus musculus DnaJ heat shock protein family member C30 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385135,064,242 - 135,064,302EPDNEW
RGD ID:6837369
Promoter ID:MM_KWN:44336
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   ES_Cell,   Liver,   Lung,   Spleen
Transcripts:NM_025362
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,539,906 - 135,540,406 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913364 AgrOrtholog
Ensembl Genes ENSMUSG00000061118 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000094318 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000071263 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DnaJ_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  J_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66114 UniProtKB/Swiss-Prot
MGD MGI:1913364 ENTREZGENE
NCBI Gene 66114 ENTREZGENE
Pfam DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnajc30 PhenoGen
PRINTS JDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNAJ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.178012 ENTREZGENE
UniProt DJC30_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6IS32_MOUSE UniProtKB/TrEMBL
  Q6P8Z3_MOUSE UniProtKB/TrEMBL
  Q7TMI2_MOUSE UniProtKB/TrEMBL
  Q9CY89_MOUSE UniProtKB/TrEMBL
  Q9DBI3_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 Dnajc30  DnaJ heat shock protein family (Hsp40) member C30    DnaJ (Hsp40) homolog, subfamily C, member 30  Symbol and/or name change 5135510 APPROVED