(+)-schisandrin B multiple interactions ISO RGD:1309070 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CTSA mRNA] CTD PMID:31150632 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:1309070 6480464 2 more ... CTD PMID:19414516 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of CTSA mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTSA mRNA CTD PMID:17942748 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CTSA mRNA CTD PMID:15289156 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1319205 6480464 Tetrachlorodibenzodioxin results in increased expression of CTSA mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTSA mRNA, Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CTSA promoter] CTD PMID:17942748 , PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1309070 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSA mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1309070 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CTSA mRNA] CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CTSA mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression ISO RGD:1309070 6480464 2, 4-dinitrotoluene affects the expression of CTSA mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO RGD:1309070 6480464 2, 6-dinitrotoluene affects the expression of CTSA mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO RGD:1319205 6480464 Lactic Acid results in decreased expression of CTSA mRNA CTD PMID:30851411 3',5'-cyclic AMP multiple interactions ISO RGD:1309070 6480464 2 more ... CTD PMID:19414516 aflatoxin B1 increases methylation ISO RGD:1319205 6480464 Aflatoxin B1 results in increased methylation of CTSA intron CTD PMID:30157460 all-trans-retinoic acid increases expression ISO RGD:1319205 6480464 Tretinoin results in increased expression of CTSA mRNA CTD PMID:23724009 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CTSA mRNA CTD PMID:23650126 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CTSA mRNA CTD PMID:25270620 atrazine decreases expression ISO RGD:1319205 6480464 Atrazine results in decreased expression of CTSA mRNA CTD PMID:22378314 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CTSA mRNA CTD PMID:22228805 benzo[a]pyrene multiple interactions EXP 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of CTSA mRNA] CTD PMID:22228805 bisphenol A affects expression ISO RGD:1309070 6480464 bisphenol A affects the expression of CTSA mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:1319205 6480464 bisphenol A results in increased expression of CTSA mRNA CTD PMID:29275510 bleomycin A2 affects expression EXP 6480464 Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 butanal decreases expression ISO RGD:1319205 6480464 butyraldehyde results in decreased expression of CTSA mRNA CTD PMID:26079696 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CTSA mRNA CTD PMID:30030080 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of CTSA mRNA CTD PMID:25554681 , PMID:25620056 cisplatin multiple interactions ISO RGD:1319205 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of CTSA mRNA CTD PMID:27392435 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CTSA mRNA CTD PMID:25270620 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of CTSA mRNA CTD PMID:17585979 , PMID:23811191 copper atom multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of CTSA mRNA CTD PMID:15467011 copper(0) multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of CTSA mRNA CTD PMID:15467011 copper(2+) multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of CTSA mRNA CTD PMID:15467011 cyclosporin A decreases expression ISO RGD:1319205 6480464 Cyclosporine results in decreased expression of CTSA mRNA CTD PMID:25562108 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of CTSA mRNA CTD PMID:15289156 divanadium pentaoxide affects expression EXP 6480464 vanadium pentoxide affects the expression of CTSA mRNA CTD PMID:26210822 doxorubicin affects expression ISO RGD:1319205 6480464 Doxorubicin affects the expression of CTSA mRNA, Doxorubicin affects the expression of CTSA protein CTD PMID:29385562 , PMID:29803840 elemental selenium increases expression ISO RGD:1319205 6480464 Selenium results in increased expression of CTSA mRNA CTD PMID:19244175 flutamide decreases expression ISO RGD:1309070 6480464 Flutamide results in decreased expression of CTSA mRNA CTD PMID:24136188 genistein increases expression EXP 6480464 Genistein results in increased expression of CTSA mRNA CTD PMID:15289156 gentamycin increases expression ISO RGD:1309070 6480464 Gentamicins results in increased expression of CTSA mRNA CTD PMID:22061828 glafenine decreases expression ISO RGD:1309070 6480464 Glafenine results in decreased expression of CTSA mRNA CTD PMID:24136188 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of CTSA mRNA CTD PMID:21829687 lead diacetate increases expression ISO RGD:1309070 6480464 lead acetate results in increased expression of CTSA mRNA CTD PMID:11578147 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of CTSA protein CTD PMID:26558463 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CTSA mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1319205 6480464 Acetaminophen results in increased expression of CTSA mRNA CTD PMID:25704631 perfluorododecanoic acid increases expression ISO RGD:1309070 6480464 perfluorododecanoic acid results in increased expression of CTSA protein CTD PMID:26168851 pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CTSA mRNA] CTD PMID:20059764 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CTSA mRNA CTD PMID:20059764 , PMID:23811191 rac-lactic acid decreases expression ISO RGD:1319205 6480464 Lactic Acid results in decreased expression of CTSA mRNA CTD PMID:30851411 selenium atom increases expression ISO RGD:1319205 6480464 Selenium results in increased expression of CTSA mRNA CTD PMID:19244175 silver atom decreases expression EXP 6480464 Silver results in decreased expression of CTSA mRNA CTD PMID:27131904 silver(0) decreases expression EXP 6480464 Silver results in decreased expression of CTSA mRNA CTD PMID:27131904 silver(1+) decreases expression EXP 6480464 Silver results in decreased expression of CTSA mRNA CTD PMID:27131904 sodium arsenite affects expression ISO RGD:1319205 6480464 sodium arsenite affects the expression of CTSA mRNA CTD PMID:20816728 Soman increases expression ISO RGD:1309070 6480464 Soman results in increased expression of CTSA mRNA CTD PMID:19281266 tamibarotene increases expression ISO RGD:1319205 6480464 tamibarotene results in increased expression of CTSA mRNA CTD PMID:17229644 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of CTSA mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:1309070 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CTSA mRNA] CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:1309070 6480464 Carbon Tetrachloride results in decreased expression of CTSA mRNA CTD PMID:31150632 valproic acid increases expression ISO RGD:1319205 6480464 Valproic Acid results in increased expression of CTSA mRNA CTD PMID:23179753 , PMID:27188386
Biological Process negative regulation of chaperone-mediated autophagy IMP 2290270 (MGI:MGI:5700310, PMID:12505983) ParkinsonsUK-UCL MGI:MGI:5700310 , PMID:12505983 negative regulation of chaperone-mediated autophagy ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 proteolysis ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 proteolysis involved in cellular protein catabolic process IBA PANTHER:PTN000210642 , PomBase:SPAC1296.03c2290270 (PMID:21873635) GO_Central PMID:21873635 regulation of protein stability IMP 2290270 (MGI:MGI:5700310, PMID:12505983) ParkinsonsUK-UCL MGI:MGI:5700310 , PMID:12505983 regulation of protein stability ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Cellular Component intracellular membrane-bounded organelle ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 lysosome IEA UniProtKB-KW:KW-0458 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 mitochondrion HDA 2290270 (MGI:MGI:2682130, PMID:14651853) MGI MGI:MGI:2682130 , PMID:14651853 nucleoplasm ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Molecular Function carboxypeptidase activity IEA UniProtKB-KW:KW-0121 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 hydrolase activity IEA UniProtKB-KW:KW-0378 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 peptidase activity IEA UniProtKB-KW:KW-0645 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 protein binding IPI UniProtKB:O35657 2290270 (MGI:MGI:2181233, PMID:9425240) MGI MGI:MGI:2181233 , PMID:9425240 serine-type carboxypeptidase activity ISO UniProtKB:P10619 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 serine-type carboxypeptidase activity IBA MGI:MGI:1921867 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 serine-type carboxypeptidase activity IBA MGI:MGI:1921867 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635
Gene-Chemical Interaction Annotations
