Ctsa (cathepsin A) - Rat Genome Database

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Gene: Ctsa (cathepsin A) Mus musculus
Analyze
Symbol: Ctsa
Name: cathepsin A
RGD ID: 1319206
MGI Page MGI
Description: Predicted to enable serine-type carboxypeptidase activity. Involved in negative regulation of chaperone-mediated autophagy and regulation of protein stability. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in galactosialidosis and lysosomal storage disease. Orthologous to human CTSA (cathepsin A).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AU019505; carboxypeptidase C; carboxypeptidase L; lysosomal protective protein; P; Pp; PPCA; Ppgb; protective protein cathepsin A; protective protein for beta-galactosidase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm17871  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,674,792 - 164,682,952 (+)NCBIGRCm39mm39
GRCm39 Ensembl2164,674,793 - 164,682,952 (+)Ensembl
GRCm382164,832,872 - 164,841,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,832,873 - 164,841,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,658,373 - 164,666,532 (+)NCBIGRCm37mm9NCBIm37
MGSCv362164,524,078 - 164,532,237 (+)NCBImm8
Celera2170,770,535 - 170,778,698 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (ISO)
4,4'-sulfonyldiphenol  (EXP)
aconitine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ampicillin  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
butanal  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
chloroquine  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP)
divanadium pentaoxide  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
fenthion  (EXP)
flutamide  (ISO)
folic acid  (EXP)
genistein  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
ivermectin  (ISO)
L-cysteine  (ISO)
lead diacetate  (EXP,ISO)
methidathion  (EXP)
metronidazole  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
neomycin  (ISO)
ochratoxin A  (ISO)
paracetamol  (EXP,ISO)
perfluorododecanoic acid  (ISO)
pirinixic acid  (EXP)
quizartinib  (ISO)
rac-lactic acid  (ISO)
remdesivir  (ISO)
selenium atom  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
T-2 toxin  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Protective protein gene mutations in galactosialidosis. Shimmoto M, etal., J Clin Invest. 1993 Jun;91(6):2393-8.
Additional References at PubMed
PMID:2106523   PMID:3136930   PMID:7590240   PMID:7959780   PMID:9174165   PMID:9425240   PMID:9736781   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11212324  
PMID:12023988   PMID:12477932   PMID:12505983   PMID:12520002   PMID:12548663   PMID:14579412   PMID:14610273   PMID:14681479   PMID:14960280   PMID:15084520   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16170054   PMID:17522420   PMID:18391110   PMID:18799693   PMID:19066718   PMID:19666471   PMID:19714866   PMID:19889639   PMID:20388541   PMID:21873635  
PMID:22001501   PMID:23495688   PMID:23520133   PMID:24357053   PMID:24586188   PMID:28234994   PMID:30550785   PMID:32325033   PMID:32529664   PMID:32647007  


Genomics

Comparative Map Data
Ctsa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,674,792 - 164,682,952 (+)NCBIGRCm39mm39
GRCm39 Ensembl2164,674,793 - 164,682,952 (+)Ensembl
GRCm382164,832,872 - 164,841,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,832,873 - 164,841,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,658,373 - 164,666,532 (+)NCBIGRCm37mm9NCBIm37
MGSCv362164,524,078 - 164,532,237 (+)NCBImm8
Celera2170,770,535 - 170,778,698 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
CTSA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,891,335 - 45,898,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2045,890,144 - 45,898,949 (+)EnsemblGRCh38hg38GRCh38
GRCh372044,519,974 - 44,527,459 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,952,998 - 43,960,866 (+)NCBINCBI36hg18NCBI36
Build 342043,953,612 - 43,960,863NCBI
Celera2041,231,053 - 41,238,921 (+)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2041,261,571 - 41,269,436 (+)NCBIHuRef
CHM1_12044,422,715 - 44,430,579 (+)NCBICHM1_1
T2T-CHM13v2.02047,627,833 - 47,635,315 (+)NCBI
Ctsa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23153,569,106 - 153,574,983 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3153,568,381 - 153,576,215 (+)Ensembl
Rnor_6.03161,298,750 - 161,304,627 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,298,962 - 161,304,625 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,483,817 - 167,489,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,866,335 - 155,871,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13155,772,370 - 155,778,034 (+)NCBI
Celera3152,176,711 - 152,182,414 (+)NCBICelera
Cytogenetic Map3q42NCBI
Ctsa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,399,151 - 11,405,069 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,399,151 - 11,405,069 (-)NCBIChiLan1.0ChiLan1.0
CTSA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12043,315,722 - 43,324,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,316,530 - 43,324,671 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02042,229,064 - 42,237,627 (+)NCBIMhudiblu_PPA_v0panPan3
CTSA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,183,090 - 33,189,248 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,183,090 - 33,189,248 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,710,110 - 32,716,269 (+)NCBI
ROS_Cfam_1.02433,893,407 - 33,899,565 (+)NCBI
ROS_Cfam_1.0 Ensembl2433,893,230 - 33,902,559 (+)Ensembl
UMICH_Zoey_3.12433,151,886 - 33,158,036 (+)NCBI
UNSW_CanFamBas_1.02433,267,003 - 33,273,167 (+)NCBI
UU_Cfam_GSD_1.02433,806,176 - 33,812,343 (+)NCBI
Ctsa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,677,621 - 191,683,147 (-)NCBI
SpeTri2.0NW_0049365147,131,263 - 7,136,775 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTSA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,082,448 - 48,089,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,082,480 - 48,089,971 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,729,009 - 53,736,612 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CTSA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,986,036 - 17,993,866 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl217,984,310 - 17,993,489 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605066,625,707 - 66,634,343 (-)NCBIVero_WHO_p1.0
Ctsa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,686,027 - 8,691,898 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247908,686,027 - 8,692,119 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH136414  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382164,839,303 - 164,839,506UniSTSGRCm38
MGSCv372164,664,803 - 164,665,006UniSTSGRCm37
Celera2170,776,965 - 170,777,168UniSTS
Cytogenetic Map2H3UniSTS
cM Map296.0UniSTS
cM Map293.0UniSTS
U37226  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382164,839,579 - 164,839,660UniSTSGRCm38
MGSCv372164,665,079 - 164,665,160UniSTSGRCm37
Celera2170,777,241 - 170,777,322UniSTS
Cytogenetic Map2H3UniSTS
cM Map293.0UniSTS
cM Map296.0UniSTS
Whitehead/MRC_RH21883.83UniSTS
J05261  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382164,839,400 - 164,839,508UniSTSGRCm38
MGSCv372164,664,900 - 164,665,008UniSTSGRCm37
Celera2170,777,062 - 170,777,170UniSTS
Cytogenetic Map2H3UniSTS
cM Map293.0UniSTS
cM Map296.0UniSTS
Whitehead/MRC_RH21886.25UniSTS
Ppgb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382164,838,897 - 164,839,459UniSTSGRCm38
MGSCv372164,664,397 - 164,664,959UniSTSGRCm37
Celera2170,776,559 - 170,777,121UniSTS
Cytogenetic Map2H3UniSTS
cM Map296.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155823920181755017Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156196464181755017Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158078337178442452Mouse
12910800Pwgrq3_mpre-weaning growth rate QTL 3 (mouse)2160611165169794802Mouse
12910810Pwbwq2_mpre-weaning body weight QTL 2 (mouse)2160611165169794802Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162433493181755017Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162736926178442452Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162736926178442452Mouse
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163486407181755017Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163486407181755017Mouse
1300676Prdt2_mprion disease incubation time 2 (mouse)Not determined2164515154181755017Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4308
Count of miRNA genes:784
Interacting mature miRNAs:1060
Transcripts:ENSMUST00000017904, ENSMUST00000103092, ENSMUST00000103093, ENSMUST00000127650, ENSMUST00000128596, ENSMUST00000130959, ENSMUST00000133077, ENSMUST00000133502, ENSMUST00000140213, ENSMUST00000143293, ENSMUST00000143780, ENSMUST00000144580, ENSMUST00000146525, ENSMUST00000147883, ENSMUST00000151493, ENSMUST00000152721, ENSMUST00000155061
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001038492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK019861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB004412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY319945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX209432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000103092   ⟹   ENSMUSP00000099381
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,821 - 164,682,952 (+)Ensembl
GRCm38.p6 Ensembl2164,832,901 - 164,841,032 (+)Ensembl
RefSeq Acc Id: ENSMUST00000103093   ⟹   ENSMUSP00000099382
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,793 - 164,681,939 (+)Ensembl
GRCm38.p6 Ensembl2164,832,873 - 164,840,019 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127650   ⟹   ENSMUSP00000115514
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,846 - 164,677,611 (+)Ensembl
GRCm38.p6 Ensembl2164,832,926 - 164,835,691 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128596
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,993 - 164,678,392 (+)Ensembl
GRCm38.p6 Ensembl2164,834,073 - 164,836,472 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130959
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,950 - 164,677,113 (+)Ensembl
GRCm38.p6 Ensembl2164,834,030 - 164,835,193 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133077
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,950 - 164,678,955 (+)Ensembl
GRCm38.p6 Ensembl2164,834,030 - 164,837,035 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133502
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,807 - 164,675,679 (+)Ensembl
GRCm38.p6 Ensembl2164,832,887 - 164,833,759 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140213
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,679,102 - 164,679,580 (+)Ensembl
GRCm38.p6 Ensembl2164,837,182 - 164,837,660 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143293
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,676,230 - 164,677,641 (+)Ensembl
GRCm38.p6 Ensembl2164,834,310 - 164,835,721 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143780   ⟹   ENSMUSP00000123413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,735 - 164,678,922 (+)Ensembl
GRCm38.p6 Ensembl2164,833,815 - 164,837,002 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144580
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,676,393 - 164,677,389 (+)Ensembl
GRCm38.p6 Ensembl2164,834,473 - 164,835,469 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146525
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,727 - 164,676,341 (+)Ensembl
GRCm38.p6 Ensembl2164,833,807 - 164,834,421 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147883
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,846 - 164,675,699 (+)Ensembl
GRCm38.p6 Ensembl2164,832,926 - 164,833,779 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151493   ⟹   ENSMUSP00000116210
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,674,829 - 164,675,982 (+)Ensembl
GRCm38.p6 Ensembl2164,832,909 - 164,834,062 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152721
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,778 - 164,678,397 (+)Ensembl
GRCm38.p6 Ensembl2164,833,858 - 164,836,477 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155061
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,675,767 - 164,676,794 (+)Ensembl
GRCm38.p6 Ensembl2164,833,847 - 164,834,874 (+)Ensembl
RefSeq Acc Id: NM_001038492   ⟹   NP_001033581
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392164,674,792 - 164,682,952 (+)NCBI
GRCm382164,832,872 - 164,841,032 (+)NCBI
MGSCv372164,658,373 - 164,666,532 (+)RGD
Celera2170,770,534 - 170,778,698 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008906   ⟹   NP_032932
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392164,675,693 - 164,682,952 (+)NCBI
GRCm382164,833,773 - 164,841,032 (+)NCBI
MGSCv372164,658,373 - 164,666,532 (+)RGD
Celera2170,770,534 - 170,778,698 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030248567   ⟹   XP_030104427
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392164,674,810 - 164,681,504 (+)NCBI
GRCm382164,832,904 - 164,839,584 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032932   ⟸   NM_008906
- Peptide Label: isoform a preproprotein
- UniProtKB: G3X8T3 (UniProtKB/TrEMBL),   Q544R6 (UniProtKB/TrEMBL),   Q9D2D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001033581   ⟸   NM_001038492
- Peptide Label: isoform b preproprotein
- UniProtKB: P16675 (UniProtKB/Swiss-Prot),   Q544R6 (UniProtKB/TrEMBL),   Q9D2D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104427   ⟸   XM_030248567
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000123413   ⟸   ENSMUST00000143780
RefSeq Acc Id: ENSMUSP00000115514   ⟸   ENSMUST00000127650
RefSeq Acc Id: ENSMUSP00000116210   ⟸   ENSMUST00000151493
RefSeq Acc Id: ENSMUSP00000099382   ⟸   ENSMUST00000103093
RefSeq Acc Id: ENSMUSP00000099381   ⟸   ENSMUST00000103092

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16675-F1-model_v2 AlphaFold P16675 1-474 view protein structure

Promoters
RGD ID:6831105
Promoter ID:MM_KWN:32962
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001038492,   NM_008906,   OTTMUST00000002271,   OTTMUST00000002272,   OTTMUST00000039370,   OTTMUST00000039371
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362164,658,234 - 164,658,734 (+)MPROMDB
RGD ID:6831097
Promoter ID:MM_KWN:32963
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B6
Transcripts:ENSMUST00000109318,   ENSMUST00000109321,   ENSMUST00000109323,   OTTMUST00000002273,   OTTMUST00000002274,   OTTMUST00000002275,   OTTMUST00000002276,   OTTMUST00000002277,   OTTMUST00000039367,   OTTMUST00000039368,   OTTMUST00000039369,   OTTMUST00000039372
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362164,659,151 - 164,660,422 (+)MPROMDB
RGD ID:6831104
Promoter ID:MM_KWN:32964
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000002279
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362164,662,021 - 164,662,567 (+)MPROMDB
RGD ID:6847640
Promoter ID:MM_ACW:30477
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:CTSA.KSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362164,664,156 - 164,664,737 (+)MPROMDB
RGD ID:6879694
Promoter ID:EPDNEW_M3298
Type:initiation region
Name:Ctsa_2
Description:Mus musculus cathepsin A , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3300  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382164,832,909 - 164,832,969EPDNEW
RGD ID:6879698
Promoter ID:EPDNEW_M3300
Type:initiation region
Name:Ctsa_1
Description:Mus musculus cathepsin A , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3298  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382164,833,806 - 164,833,866EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97748 AgrOrtholog
Ensembl Genes ENSMUSG00000017760 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000099381 ENTREZGENE
  ENSMUSP00000099381.3 UniProtKB/TrEMBL
  ENSMUSP00000099382 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115514.2 UniProtKB/TrEMBL
  ENSMUSP00000116210.3 UniProtKB/TrEMBL
  ENSMUSP00000123413.3 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103092 ENTREZGENE
  ENSMUST00000103092.9 UniProtKB/TrEMBL
  ENSMUST00000103093 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000127650.8 UniProtKB/TrEMBL
  ENSMUST00000143780.9 UniProtKB/TrEMBL
  ENSMUST00000151493.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser_caboxypep_his_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser_caboxypep_ser_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19025 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97748 ENTREZGENE
NCBI Gene 19025 ENTREZGENE
PANTHER PTHR11802 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_S10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ctsa PhenoGen
PRINTS CRBOXYPTASEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_SER_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CARBOXYPEPT_SER_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A5J7_MOUSE UniProtKB/TrEMBL
  A2A5J8_MOUSE UniProtKB/TrEMBL
  A2A5J9_MOUSE UniProtKB/TrEMBL
  G3X8T3 ENTREZGENE, UniProtKB/TrEMBL
  P16675 ENTREZGENE, UniProtKB/Swiss-Prot
  Q544R6 ENTREZGENE, UniProtKB/TrEMBL
  Q9D2D1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q8VEF6 UniProtKB/Swiss-Prot