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Gene: Ctsa (cathepsin A) Mus musculus
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Symbol: Ctsa
Name: cathepsin A
Description: Predicted to have serine-type carboxypeptidase activity. Involved in negative regulation of chaperone-mediated autophagy and regulation of protein stability. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in galactosialidosis and lysosomal storage disease. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Orthologous to human CTSA (cathepsin A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AU019505; carboxypeptidase C; carboxypeptidase L; lysosomal protective protein; PPCA; Ppgb; protective protein cathepsin A; protective protein for beta-galactosidase
Orthologs:
Homo sapiens (human) : CTSA (cathepsin A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ctsa (cathepsin A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctsa (cathepsin A)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSA (cathepsin A)
Canis lupus familiaris (dog) : CTSA (cathepsin A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsa (cathepsin A)
Sus scrofa (pig) : CTSA (cathepsin A)
more info ...
Related Pseudogenes: Gm17871  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382164,832,872 - 164,841,032 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372164,658,373 - 164,666,532 (+)NCBIGRCm37mm9NCBIm37
MGSCv362164,524,078 - 164,532,237 (+)NCBImm8
Celera2170,770,534 - 170,778,698 (+)NCBICelera
Cytogenetic Map2 H3NCBI
cM Map285.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ctsa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319206
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.