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Gene: Ago1 (argonaute RISC catalytic subunit 1) Mus musculus
Symbol: Ago1
Name: argonaute RISC catalytic subunit 1
RGD ID: 1312164
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and miRNA binding activity. Involved in miRNA metabolic process; positive regulation of NIK/NF-kappaB signaling; and positive regulation of transcription by RNA polymerase II. Localizes to several cellular components, including P-body; RISC complex; and cytosol. Is expressed in several structures, including 2-cell stage embryo; central nervous system; lung epithelium; sensory organ; and tooth. Orthologous to human AGO1 (argonaute RISC component 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: argonaute 1; argonaute RISC catalytic component 1; argonaute1; eIF-2C 1; Eif2c; eIF2C 1; Eif2c1; eukaryotic translation initiation factor 2C, 1; mAgo1; Piwi/Argonaute family protein meIF2C1; protein argonaute-1
Homo sapiens (human) : AGO1 (argonaute RISC component 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ago1 (argonaute RISC component 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago1 (argonaute RISC component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO1 (argonaute RISC component 1)
Canis lupus familiaris (dog) : AGO1 (argonaute RISC component 1)
Sus scrofa (pig) : AGO1 (argonaute RISC component 1)
Chlorocebus sabaeus (African green monkey) : AGO1 (argonaute RISC component 1)
Heterocephalus glaber (naked mole-rat) : Ago1 (argonaute RISC component 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394126,328,805 - 126,362,500 (-)NCBI
GRCm384126,435,012 - 126,468,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4126,435,012 - 126,468,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv374126,112,256 - 126,145,665 (-)NCBIGRCm37mm9NCBIm37
MGSCv364125,941,807 - 125,970,725 (-)NCBImm8
Celera4124,771,815 - 124,805,219 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ago1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312164
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.