Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | EXP | | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of AGO4 mRNA | CTD | PMID:24763279 | (+)-schisandrin B | multiple interactions | ISO | Ago4 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AGO4 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | affects expression | ISO | Ago4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of AGO4 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of AGO4 mRNA | CTD | PMID:22217510 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of AGO4 mRNA | CTD | PMID:31614463 | 17beta-estradiol | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of AGO4 mRNA | CTD | PMID:32145629 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ago4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of AGO4 mRNA | CTD | PMID:21570461 | 6-propyl-2-thiouracil | increases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of AGO4 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of AGO4 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of AGO4 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Ago4 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of AGO4 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of AGO4 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of AGO4 mRNA | CTD | PMID:23724009 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of AGO4 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of AGO4 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of AGO4 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Ago4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of AGO4 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | Ago4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of AGO4 mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of AGO4 mRNA | CTD | PMID:30816183 more ... | bisphenol A | increases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of AGO4 mRNA | CTD | PMID:34947998 | Bisphenol A diglycidyl ether | affects splicing | ISO | Ago4 (Mus musculus) | 6480464 | 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of AGO4 mRNA | CTD | PMID:36464114 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of AGO4 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AGO4 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AGO4 mRNA | CTD | PMID:37325564 | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of AGO4 mRNA | CTD | PMID:24752500 | carbon nanotube | decreases expression | ISO | Ago4 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to AGO4 gene] | CTD | PMID:28238834 | chromium(6+) | affects expression | ISO | Ago4 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of AGO4 mRNA | CTD | PMID:28472532 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of AGO4 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of AGO4 mRNA | CTD | PMID:27392435 | Cuprizon | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of AGO4 mRNA | CTD | PMID:26577399 | diclofenac | affects expression | EXP | | 6480464 | Diclofenac affects the expression of AGO4 mRNA | CTD | PMID:24752500 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of AGO4 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of AGO4 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of AGO4 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AGO4 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of AGO4 mRNA | CTD | PMID:23649840 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of AGO4 mRNA | CTD | PMID:21867686 | fonofos | decreases methylation | EXP | | 6480464 | Fonofos results in decreased methylation of AGO4 promoter | CTD | PMID:22847954 | methimazole | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of AGO4 mRNA | CTD | PMID:30047161 | methotrexate | affects expression | ISO | Ago4 (Mus musculus) | 6480464 | Methotrexate affects the expression of AGO4 mRNA | CTD | PMID:18502557 | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of AGO4 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of AGO4 mRNA | CTD | PMID:28001369 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of AGO4 mRNA | CTD | PMID:35430440 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of AGO4 mRNA | CTD | PMID:22230336 | parathion | decreases methylation | EXP | | 6480464 | Parathion results in decreased methylation of AGO4 promoter | CTD | PMID:22847954 | PCB138 | multiple interactions | ISO | Ago4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pentanal | decreases expression | EXP | | 6480464 | pentanal results in decreased expression of AGO4 mRNA | CTD | PMID:26079696 | phenobarbital | affects expression | ISO | Ago4 (Mus musculus) | 6480464 | Phenobarbital affects the expression of AGO4 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of AGO4 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AGO4 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Ago4 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of AGO4 mRNA | CTD | PMID:20813756 | potassium dichromate | decreases expression | ISO | Ago4 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of AGO4 mRNA | CTD | PMID:23608068 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of AGO4 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of AGO4 mRNA | CTD | PMID:26014281 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of AGO4 mRNA | CTD | PMID:26014281 | sulfadimethoxine | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of AGO4 mRNA | CTD | PMID:30047161 | terbufos | decreases methylation | EXP | | 6480464 | terbufos results in decreased methylation of AGO4 promoter | CTD | PMID:22847954 | tetrachloromethane | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of AGO4 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Ago4 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AGO4 mRNA] | CTD | PMID:31150632 | tetraphene | decreases expression | ISO | Ago4 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of AGO4 mRNA | CTD | PMID:26377693 | thioacetamide | decreases expression | ISO | Ago4 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of AGO4 mRNA | CTD | PMID:34492290 | trimellitic anhydride | decreases expression | ISO | Ago4 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of AGO4 mRNA | CTD | PMID:19042947 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of AGO4 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of AGO4 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AGO4 mRNA | CTD | PMID:27188386 | |