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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734157
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c29
Name: cytochrome P450, family 2, subfamily c, polypeptide 29
Acc ID: CHEBI:2430
Term: aconitine
Definition: A diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively.
Chemical ID: MESH:D000157
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c29increases metabolic processingISOCYP2C8 (Homo sapiens)6480464CTDCYP2C8 protein results in increased metabolism of AconitinePMID:21277363
Cyp2c29multiple interactionsISOCYP2C8 (Homo sapiens)6480464CTD[Gemfibrozil results in decreased activity of CYP2C8 protein] which affects the chemical synthesis of Aconitine metabolitePMID:21277363
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