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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:omeprazole
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Accession:CHEBI:7772 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
Synonyms:exact_synonym: rac-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
 related_synonym: 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole;   Antra;   Audazol;   Belmazol;   Ceprandal;   Danlox;   Desec;   Elgam;   Emeproton;   Gasec;   Gastrimut;   Indurgan;   Inhibitron;   Losec;   OMEP;   OMP;   OMZ;   Olit;   Omapren;   Omebeta;   Prazidec;   Procelac;   Sanamidol;   Ulceral;   Ulcesep;   Ultop;   omeprazol;   omeprazolum
 xref: CAS:73590-58-6;   DrugBank:DB00338;   KEGG:C07324;   KEGG:D00455
 xref_mesh: MESH:D009853
 xref: PMID:11060758;   PMID:11208500;   PMID:11210716;   PMID:11304936;   PMID:11321383;   PMID:11395292;   PMID:11404722;   PMID:11459434;   PMID:11568514;   PMID:11700946;   PMID:11774962;   PMID:11807212;   PMID:11851112;   PMID:11903739;   PMID:11962536;   PMID:12072663;   PMID:12135028;   PMID:12235248;   PMID:12495367;   PMID:12683615;   PMID:13680386;   PMID:14616415;   PMID:14708212;   PMID:14725575;   PMID:15004262;   PMID:15125696;   PMID:15586641;   PMID:15598025;   PMID:15684503;   PMID:15707461;   PMID:15774534;   PMID:16080278;   PMID:16129922;   PMID:16259581;   PMID:16276979;   PMID:16380990;   PMID:16386527;   PMID:16397810;   PMID:16440530;   PMID:16998872;   PMID:17049542;   PMID:17384694;   PMID:17532167;   PMID:18294333;   PMID:18366242;   PMID:18416943;   PMID:18448060;   PMID:18498918;   PMID:18520598;   PMID:18571645;   PMID:18616070;   PMID:18793272;   PMID:18818790;   PMID:19150046;   PMID:19166730;   PMID:19176055;   PMID:19236757;   PMID:19327607;   PMID:19383986;   PMID:19434360;   PMID:19470853;   PMID:19517893;   PMID:19746659;   PMID:19796313;   PMID:19801857;   PMID:19937171;   Patent:EP5129;   Patent:US4255431;   Patent:US5693818;   Reaxys:3628192;   VSDB:1827;   Wikipedia:Omeprazole


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omeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 increases expression ISO Omeprazole results in increased expression of ABCA1 mRNA CTD PMID:20060385 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity ISO Omeprazole results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects expression
multiple interactions		 ISO Omeprazole affects the expression of ABCB1A mRNA
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein]		 CTD PMID:19483382 PMID:30452898 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases expression ISO Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions ISO [Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein CTD PMID:35447140 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 increases expression ISO Omeprazole results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 affects expression ISO Omeprazole affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression
multiple interactions		 ISO Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein
Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]		 CTD PMID:20804740 PMID:31348918 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression ISO Omeprazole affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439 		JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression ISO Omeprazole affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 5:31,107,410...31,112,439
Ensembl chr 5:31,107,410...31,112,435 		JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression ISO Omeprazole affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 9:106,324,936...106,330,122
Ensembl chr 9:106,324,658...106,330,122 		JBrowse link
G Abhd17a abhydrolase domain containing 17A affects expression ISO Omeprazole affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr10:80,419,483...80,426,199
Ensembl chr10:80,419,488...80,426,175 		JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha affects expression ISO Omeprazole affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acadl acyl-Coenzyme A dehydrogenase, long-chain affects expression ISO Omeprazole affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Omeprazole results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Aco1 aconitase 1 affects expression ISO Omeprazole affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Aco2 aconitase 2, mitochondrial affects expression ISO Omeprazole affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334 		JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression ISO Omeprazole affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr13:91,889,635...91,934,271
Ensembl chr13:91,889,631...91,934,267 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression ISO Omeprazole affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr12:84,084,028...84,091,497
Ensembl chr12:84,085,153...84,095,375 		JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression ISO Omeprazole affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303 		JBrowse link
G Add1 adducin 1 affects expression ISO Omeprazole affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr 5:34,731,008...34,789,652
Ensembl chr 5:34,731,008...34,789,652 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression ISO Omeprazole affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653 		JBrowse link
G Adtrp androgen dependent TFPI regulating protein affects expression ISO Omeprazole affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160 		JBrowse link
G Afm afamin affects expression ISO Omeprazole affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402 		JBrowse link
G Agt angiotensinogen affects expression ISO Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression ISO Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases response to substance
affects localization
decreases expression
increases expression
increases activity
decreases activity		 ISO
EXP		 AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein]
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
AHR protein results in increased susceptibility to Omeprazole
Omeprazole affects the localization of AHR protein
Omeprazole results in decreased activity of AHR protein		 CTD PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 More... NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 affects expression ISO Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 affects expression ISO Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects expression
multiple interactions		 ISO Omeprazole affects the expression of ALDH1A1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA		 CTD PMID:19483382 PMID:22687989 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 increases expression ISO Omeprazole results in increased expression of ALDH1A3 mRNA CTD PMID:12040753 NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial affects expression ISO Omeprazole affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 increases expression ISO Omeprazole results in increased expression of ALDH3A1 mRNA CTD PMID:12040753 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Alkbh7 alkB homolog 7 affects expression ISO Omeprazole affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr17:57,304,339...57,306,340
Ensembl chr17:57,304,339...57,306,322 		JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression ISO Omeprazole results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:94,218,827...94,232,673
Ensembl chr11:94,218,827...94,232,667 		JBrowse link
G Ap2m1 adaptor-related protein complex 2, mu 1 subunit affects expression ISO Omeprazole affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr16:20,354,230...20,363,659
Ensembl chr16:20,354,228...20,363,659 		JBrowse link
G Apcs amyloid P component, serum affects expression ISO Omeprazole affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608 		JBrowse link
G Apoa4 apolipoprotein A-IV affects expression ISO Omeprazole affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Apoh apolipoprotein H affects expression ISO Omeprazole affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222 		JBrowse link
G Apool apolipoprotein O-like affects expression ISO Omeprazole affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:111,221,049...111,282,452
Ensembl chr  X:111,221,031...111,282,452 		JBrowse link
G Arg1 arginase, liver affects expression ISO Omeprazole affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 affects expression ISO Omeprazole affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 7:117,718,113...117,728,848
Ensembl chr 7:117,718,114...117,728,885 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
affects localization		 ISO Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]
Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
Omeprazole affects the localization of ARNT protein		 CTD PMID:9395520 PMID:21703235 PMID:25826687 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression ISO Omeprazole affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr11:69,983,470...69,997,013
Ensembl chr11:69,983,470...69,997,013 		JBrowse link
G Atf5 activating transcription factor 5 affects expression ISO Omeprazole affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression ISO Omeprazole affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898 		JBrowse link
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 affects expression ISO Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:12,453,998...12,483,290
Ensembl chr  X:12,454,040...12,483,288 		JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A affects expression ISO Omeprazole affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068 		JBrowse link
G Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F affects expression ISO Omeprazole affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 6:29,467,782...29,470,508
Ensembl chr 6:29,467,717...29,470,511 		JBrowse link
G Atp7a ATPase, copper transporting, alpha polypeptide multiple interactions ISO
EXP		 Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]		 CTD PMID:25337692 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase affects expression ISO Omeprazole affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:30452898 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:30452898 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B affects expression ISO Omeprazole affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624 		JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression ISO Omeprazole affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr10:89,580,830...89,655,753
Ensembl chr10:89,580,853...89,655,733 		JBrowse link
G Bmf BCL2 modifying factor affects expression ISO Omeprazole affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168 		JBrowse link
G Bmx BMX non-receptor tyrosine kinase multiple interactions ISO BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein] CTD PMID:21861773 NCBI chr  X:162,975,838...163,041,189
Ensembl chr  X:162,975,838...163,041,189 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 affects expression ISO Omeprazole affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Btf3 basic transcription factor 3 affects expression ISO Omeprazole affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr13:98,446,405...98,453,514
Ensembl chr13:98,446,404...98,453,514 		JBrowse link
G C1qa complement component 1, q subcomponent, alpha polypeptide decreases expression ISO Omeprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114 		JBrowse link
G C1qbp complement component 1, q subcomponent binding protein affects expression ISO Omeprazole affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr11:70,868,672...70,873,852
Ensembl chr11:70,868,662...70,873,852 		JBrowse link
G C1qc complement component 1, q subcomponent, C chain decreases expression ISO Omeprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376 		JBrowse link
G C1s1 complement component 1, s subcomponent 1 affects expression ISO Omeprazole affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 6:124,507,303...124,519,340
Ensembl chr 6:124,507,304...124,519,318 		JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression ISO Omeprazole affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr16:97,656,409...97,727,248
Ensembl chr16:97,656,409...97,763,798 		JBrowse link
G C7 complement component 7 affects expression ISO Omeprazole affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr15:5,017,232...5,093,230
Ensembl chr15:5,018,244...5,093,222 		JBrowse link
G C8b complement component 8, beta polypeptide affects expression ISO Omeprazole affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745 		JBrowse link
G Cadps2 Ca2+-dependent activator protein for secretion 2 affects expression ISO Omeprazole affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 6:23,262,765...23,840,662
Ensembl chr 6:23,262,772...23,839,420 		JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression ISO Omeprazole affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 2:103,593,292...103,627,946
Ensembl chr 2:103,593,286...103,627,994 		JBrowse link
G Car2 carbonic anhydrase 2 affects expression ISO Omeprazole affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Car3 carbonic anhydrase 3 affects expression ISO Omeprazole affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
affects expression
multiple interactions		 ISO Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein
Omeprazole results in increased cleavage of CASP3 protein
Omeprazole affects the expression of CASP3 mRNA
Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]		 CTD PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cat catalase increases activity
multiple interactions		 ISO
EXP		 Omeprazole results in increased activity of CAT protein
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein]
Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]		 CTD PMID:18547560 PMID:28849987 PMID:33245926 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Omeprazole affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Omeprazole results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdo1 cysteine dioxygenase 1, cytosolic affects expression ISO Omeprazole affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462 		JBrowse link
G Cept1 choline/ethanolaminephosphotransferase 1 affects expression ISO Omeprazole affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 3:106,409,576...106,455,118
Ensembl chr 3:106,409,576...106,455,118 		JBrowse link
G Ces2h carboxylesterase 2H affects expression ISO Omeprazole affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Cfi complement component factor i affects expression
decreases expression		 ISO Omeprazole affects the expression of CFI mRNA
Omeprazole results in decreased expression of CFI mRNA		 CTD PMID:19483382 PMID:25626140 NCBI chr 3:129,630,432...129,668,978
Ensembl chr 3:129,629,533...129,668,981 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator affects metabolic processing EXP CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Chp1 calcineurin-like EF hand protein 1 affects expression ISO Omeprazole affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 2:119,378,172...119,417,505
Ensembl chr 2:119,378,178...119,417,508 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression ISO Omeprazole affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784 		JBrowse link
G Clcn4 chloride channel, voltage-sensitive 4 affects expression ISO Omeprazole affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr 7:7,285,308...7,303,837
Ensembl chr 7:7,285,308...7,303,850 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Omeprazole affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188 		JBrowse link
G Clptm1l CLPTM1-like affects expression ISO Omeprazole affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr13:73,752,121...73,768,758
Ensembl chr13:73,752,125...73,768,724 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression ISO Omeprazole affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression ISO Omeprazole affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 4:114,817,810...114,844,425
Ensembl chr 4:114,816,533...114,844,438 		JBrowse link
G Copg1 coatomer protein complex, subunit gamma 1 affects expression ISO Omeprazole affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 6:87,864,801...87,890,577
Ensembl chr 6:87,864,796...87,890,577 		JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression ISO Omeprazole affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr 5:100,666,223...100,695,668
Ensembl chr 5:100,666,175...100,695,669 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression ISO Omeprazole affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 4:21,879,646...21,912,163
Ensembl chr 4:21,879,673...21,912,162 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 affects expression ISO Omeprazole affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946 		JBrowse link
G Cpn1 carboxypeptidase N, polypeptide 1 affects expression ISO Omeprazole affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr19:43,944,746...43,974,990
Ensembl chr19:43,944,746...43,974,995 		JBrowse link
G Cpq carboxypeptidase Q affects expression ISO Omeprazole affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr15:33,083,275...33,594,698
Ensembl chr15:33,083,275...33,594,698 		JBrowse link
G Crem cAMP responsive element modulator affects expression ISO Omeprazole affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748 		JBrowse link
G Csnk2b casein kinase 2, beta polypeptide affects expression ISO Omeprazole affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression ISO Omeprazole affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970 		JBrowse link
G Ctnna1 catenin alpha 1 affects expression ISO Omeprazole affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832 		JBrowse link
G Ctsb cathepsin B decreases activity ISO Omeprazole results in decreased activity of CTSB protein CTD PMID:34871754 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein] CTD PMID:20165931 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Ctse cathepsin E decreases expression ISO Omeprazole results in decreased expression of CTSE CTD PMID:7575556 NCBI chr 1:131,566,052...131,603,245
Ensembl chr 1:131,566,044...131,603,243 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions		 ISO Omeprazole results in decreased expression of CXCR4 mRNA
AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]		 CTD PMID:25826687 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
increases expression
decreases activity		 ISO
EXP		 Omeprazole results in increased activity of CYP1A1 promoter
Omeprazole results in increased activity of CYP1A1 protein
AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]
Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]
Omeprazole results in decreased activity of CYP1A1 protein
Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA]		 CTD PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
decreases activity
multiple interactions
increases expression		 ISO
EXP		 Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein
Omeprazole results in decreased activity of CYP1A2 protein
[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein
Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA		 CTD PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
decreases activity
affects expression		 ISO
EXP		 Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
Omeprazole results in increased expression of CYP1B1 mRNA
Omeprazole results in decreased activity of CYP1B1 protein
Omeprazole affects the expression of CYP1B1 mRNA		 CTD PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 affects expression ISO Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases activity
increases activity
increases expression
affects expression		 EXP
ISO		 Omeprazole results in decreased activity of CYP2B10 protein
Omeprazole results in increased activity of CYP2B6 protein
Omeprazole results in increased expression of CYP2B6 mRNA
Omeprazole affects the expression of CYP2B3 mRNA		 CTD PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression
affects expression		 ISO Omeprazole results in increased expression of CYP2B2 protein
Omeprazole affects the expression of CYP2B2 mRNA		 CTD PMID:9152597 PMID:19483382 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 multiple interactions
increases metabolic processing		 EXP [CYP2C37 protein results in increased metabolism of Omeprazole] which results in increased chemical synthesis of 5-hydroxymethylomeprazole CTD PMID:30503582 NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 affects metabolic processing
decreases metabolic processing
increases hydroxylation
increases metabolic processing
decreases activity
multiple interactions		 ISO CYP2C19 protein affects the metabolism of Omeprazole
CYP2C19 gene alternative form results in decreased metabolism of Omeprazole
CYP2C19 protein results in increased hydroxylation of Omeprazole
CYP2C19 protein results in increased metabolism of Omeprazole
Omeprazole results in decreased activity of CYP2C19 protein
[5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel]		 CTD PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 More... NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
decreases activity		 ISO
EXP		 Omeprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]
Omeprazole results in decreased activity of CYP2C9 protein		 CTD PMID:15258107 PMID:18420780 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 affects expression
decreases activity		 ISO
EXP		 Omeprazole affects the expression of CYP2D4 mRNA
Omeprazole results in decreased activity of CYP2D6 protein		 CTD PMID:18420780 PMID:19483382 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO
EXP		 Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 PMID:36243147 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 affects expression ISO Omeprazole affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085 		JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 affects expression ISO Omeprazole affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 decreases activity EXP Omeprazole results in decreased activity of CYP3A11 protein CTD PMID:18420780 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 affects expression
increases expression		 ISO Omeprazole affects the expression of CYP3A9 mRNA
Omeprazole results in increased expression of CYP3A5 mRNA		 CTD PMID:19118567 PMID:19483382 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 decreases activity EXP Omeprazole results in decreased activity of CYP3A4 protein CTD PMID:18420780 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684 		JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 affects expression ISO Omeprazole affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772 		JBrowse link
G Dbi diazepam binding inhibitor affects expression ISO Omeprazole affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808 		JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression ISO Omeprazole affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr14:55,796,557...55,807,522
Ensembl chr14:55,797,463...55,807,522 		JBrowse link
G Dcxr dicarbonyl L-xylulose reductase affects expression ISO Omeprazole affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr11:120,615,372...120,618,110
Ensembl chr11:120,616,225...120,618,107 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Omeprazole results in increased expression of DDIT3 protein CTD PMID:27358234 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial affects expression ISO Omeprazole affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507 		JBrowse link
G Dexi dexamethasone-induced transcript affects expression ISO Omeprazole affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr16:10,348,071...10,360,918
Ensembl chr16:10,320,395...10,360,918 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression ISO Omeprazole affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression ISO Omeprazole affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression ISO Omeprazole affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression ISO Omeprazole affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr11:60,721,457...60,749,249
Ensembl chr11:60,721,457...60,751,021 		JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression ISO Omeprazole affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr17:36,190,657...36,203,562
Ensembl chr17:36,190,711...36,203,562 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression ISO Omeprazole affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr12:69,771,687...69,791,439
Ensembl chr12:69,771,724...69,791,434 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression ISO Omeprazole affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression ISO Omeprazole affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression ISO Omeprazole affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573 		JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression ISO Omeprazole affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 7:121,633,385...121,666,436
Ensembl chr 7:121,636,436...121,666,486 		JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial affects expression ISO Omeprazole affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389 		JBrowse link
G Eci1 enoyl-Coenzyme A delta isomerase 1 affects expression ISO Omeprazole affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322 		JBrowse link
G Eci2 enoyl-Coenzyme A delta isomerase 2 affects expression ISO Omeprazole affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr13:35,161,731...35,211,098
Ensembl chr13:35,161,731...35,211,079 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression ISO Omeprazole affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein] CTD PMID:18431645 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase affects expression ISO Omeprazole affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression ISO Omeprazole affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression ISO Omeprazole affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702 		JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression ISO Omeprazole affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr 5:134,648,726...134,668,263
Ensembl chr 5:134,648,575...134,668,344 		JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression ISO Omeprazole affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542 		JBrowse link
G Eno1 enolase 1, alpha non-neuron affects expression ISO Omeprazole affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336 		JBrowse link
G Enpep glutamyl aminopeptidase affects expression ISO Omeprazole affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression ISO Omeprazole affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epcam epithelial cell adhesion molecule affects expression ISO Omeprazole affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression ISO Omeprazole affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Esd esterase D/formylglutathione hydrolase affects expression ISO Omeprazole affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205 		JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide affects expression ISO Omeprazole affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224 		JBrowse link
G Faah fatty acid amide hydrolase affects expression ISO Omeprazole affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123 		JBrowse link
G Fads2 fatty acid desaturase 2 affects expression ISO Omeprazole affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110 		JBrowse link
G Fbp1 fructose bisphosphatase 1 affects expression ISO Omeprazole affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fdps farnesyl diphosphate synthetase affects expression ISO Omeprazole affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fdx2 ferredoxin 2 affects expression ISO Omeprazole affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 9:20,978,808...20,984,827
Ensembl chr 9:20,978,816...20,984,910 		JBrowse link
G Fmo1 flavin containing monooxygenase 1 affects expression ISO Omeprazole affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179 		JBrowse link
G Gamt guanidinoacetate methyltransferase affects expression ISO Omeprazole affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Omeprazole affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430 		JBrowse link
G Gast gastrin increases expression EXP
ISO		 Omeprazole results in increased expression of GAST protein CTD PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 More... NCBI chr11:100,225,233...100,227,823
Ensembl chr11:100,225,233...100,227,822 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression ISO Omeprazole affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr16:70,110,837...70,366,608
Ensembl chr16:70,110,837...70,366,604 		JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression ISO Omeprazole affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 2:118,998,269...119,002,870
Ensembl chr 2:118,998,254...119,002,871 		JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression ISO Omeprazole affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 4:20,041,963...20,066,111
Ensembl chr 4:20,042,052...20,066,750 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA CTD PMID:22687989 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034 		JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression ISO Omeprazole affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression ISO Omeprazole affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression ISO Omeprazole affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA CTD PMID:22687989 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273 		JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression ISO Omeprazole affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) affects expression ISO Omeprazole affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression ISO Omeprazole affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr 5:36,622,529...36,631,421
Ensembl chr 5:36,622,342...36,631,424 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions
increases expression		 ISO [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
Omeprazole results in increased expression of GSTA5 mRNA		 CTD PMID:17202759 PMID:22687989 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression ISO Omeprazole results in increased expression of GSTP1 mRNA CTD PMID:19118567 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 affects expression ISO Omeprazole affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 affects expression ISO Omeprazole affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792 		JBrowse link
G Gzma granzyme A affects expression ISO Omeprazole affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515 		JBrowse link
G H2-DMa histocompatibility 2, class II, locus DMa affects expression ISO Omeprazole affects the expression of HLA-DMA mRNA CTD PMID:25811541 NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075 		JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 affects expression ISO Omeprazole affects the expression of HLA-B mRNA CTD PMID:25811541 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443 		JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 affects expression ISO Omeprazole affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375 		JBrowse link
G H3f3b H3.3 histone B affects expression ISO Omeprazole affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788 		JBrowse link
G Hal histidine ammonia lyase affects expression ISO Omeprazole affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166 		JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression
increases secretion
multiple interactions		 EXP
ISO		 Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein
Omeprazole results in increased secretion of HAMP protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]		 CTD PMID:31669099 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457 		JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression ISO Omeprazole affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression ISO Omeprazole affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain affects expression ISO Omeprazole affects the expression of HBB mRNA CTD PMID:19483382
G Hdc histidine decarboxylase affects expression
multiple interactions
increases expression
increases stability		 ISO Omeprazole affects the expression of HDC mRNA
Omeprazole results in increased expression of and results in increased activity of HDC protein
Omeprazole results in increased expression of HDC mRNA
Omeprazole results in increased stability of HDC protein		 CTD PMID:12763636 PMID:19483382 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression ISO Omeprazole affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382 		JBrowse link
G Hmgn1 high mobility group nucleosomal binding domain 1 affects expression ISO Omeprazole affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr16:95,922,788...95,928,925
Ensembl chr16:95,921,818...95,928,929 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein
Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein		 CTD PMID:16712795 PMID:27725188 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression ISO Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression ISO Omeprazole affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression ISO Omeprazole affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression ISO Omeprazole affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689 		JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
decreases expression		 ISO Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein		 CTD PMID:15223672 PMID:16945336 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions ISO Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261 		JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression ISO Omeprazole affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390 		JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] CTD PMID:19232345 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 affects expression ISO Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression ISO Omeprazole affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Omeprazole affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein] CTD PMID:32418911 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein] CTD PMID:25637687 PMID:32418911 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Impa1 inositol (myo)-1(or 4)-monophosphatase 1 affects expression ISO Omeprazole affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 3:10,377,016...10,396,499
Ensembl chr 3:10,377,016...10,396,499 		JBrowse link
G Inhbe inhibin beta-E affects expression ISO Omeprazole affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280 		JBrowse link
G Isyna1 myo-inositol 1-phosphate synthase A1 affects expression ISO Omeprazole affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940 		JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 affects expression ISO Omeprazole affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310 		JBrowse link
G Jak1 Janus kinase 1 affects expression ISO Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479 		JBrowse link
G Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 affects expression ISO Omeprazole affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr 5:143,389,575...143,407,659
Ensembl chr 5:143,389,593...143,407,656 		JBrowse link
G Kdr kinase insert domain protein receptor affects expression
multiple interactions		 ISO
EXP		 Omeprazole affects the expression of KDR mRNA
Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]		 CTD PMID:19483382 PMID:26272953 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Krt8 keratin 8 affects expression ISO Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917 		JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression ISO Omeprazole affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression ISO Omeprazole affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 7:122,977,026...123,029,581
Ensembl chr 7:122,969,007...123,029,581 		JBrowse link
G Lipc lipase, hepatic affects expression ISO Omeprazole affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lox lysyl oxidase affects expression ISO Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939 		JBrowse link
G Lrp3 low density lipoprotein receptor-related protein 3 affects expression ISO Omeprazole affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 7:34,900,303...34,914,770
Ensembl chr 7:34,899,452...34,914,923 		JBrowse link
G Man2b1 mannosidase 2, alpha B1 affects expression ISO Omeprazole affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr 8:85,809,941...85,824,215
Ensembl chr 8:85,809,899...85,824,911 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 affects expression ISO Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein] CTD PMID:17406807 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Masp2 MBL associated serine protease 2 affects expression ISO Omeprazole affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956 		JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic affects expression
multiple interactions		 ISO Omeprazole affects the expression of ME1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA		 CTD PMID:19483382 PMID:22687989 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) multiple interactions ISO Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein] CTD PMID:16934674 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein] CTD PMID:16934674 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmut methylmalonyl-Coenzyme A mutase affects expression ISO Omeprazole affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879 		JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity		 EXP
ISO		 Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein]
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Omeprazole results in decreased activity of MPO protein		 CTD PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 More... NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mro maestro affects expression ISO Omeprazole affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:73,992,465...74,014,405
Ensembl chr18:73,992,456...74,014,404 		JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression ISO Omeprazole affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr17:46,957,094...46,961,058
Ensembl chr17:46,957,155...46,961,065 		JBrowse link
G Mrpl9 mitochondrial ribosomal protein L9 affects expression ISO Omeprazole affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 3:94,350,631...94,355,831
Ensembl chr 3:94,350,625...94,358,437 		JBrowse link
G Mug2 murinoglobulin 2 affects expression ISO Omeprazole affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 6:121,983,688...122,062,927
Ensembl chr 6:121,983,720...122,062,924 		JBrowse link
G Myadm myeloid-associated differentiation marker affects expression ISO Omeprazole affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 7:3,337,563...3,347,871
Ensembl chr 7:3,337,605...3,348,958 		JBrowse link
G Mycbp2 MYC binding protein 2, E3 ubiquitin protein ligase affects expression ISO Omeprazole affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr14:103,350,847...103,584,276
Ensembl chr14:103,350,847...103,584,250 		JBrowse link
G Myo1d myosin ID affects expression ISO Omeprazole affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr11:80,372,945...80,670,881
Ensembl chr11:80,372,952...80,670,851 		JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression ISO Omeprazole affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr11:69,286,617...69,287,497
Ensembl chr11:69,286,313...69,287,506 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression ISO Omeprazole affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011 		JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) affects expression ISO Omeprazole affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182 		JBrowse link
G Ndrg2 N-myc downstream regulated gene 2 affects expression ISO Omeprazole affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr14:52,142,738...52,151,463
Ensembl chr14:52,142,728...52,151,615 		JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 affects expression ISO Omeprazole affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase core subunit V3 affects expression ISO Omeprazole affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr17:31,739,089...31,750,300
Ensembl chr17:31,739,089...31,750,305 		JBrowse link
G Neu2 neuraminidase 2 affects expression ISO Omeprazole affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein] CTD PMID:27725188 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein] CTD PMID:32418911 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression ISO Omeprazole affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 4:40,970,906...41,025,992
Ensembl chr 4:40,970,906...41,025,993 		JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression ISO Omeprazole affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr15:34,572,942...34,679,739
Ensembl chr15:34,572,945...34,679,358 		JBrowse link
G Nit1 nitrilase 1 affects expression ISO Omeprazole affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr 1:171,168,145...171,173,209
Ensembl chr 1:171,165,576...171,173,214 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression ISO Omeprazole affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression
multiple interactions		 ISO
EXP		 Omeprazole results in increased expression of NQO1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA
Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein]		 CTD PMID:17202759 PMID:22687989 PMID:26272953 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA] CTD PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression
increases expression
decreases metabolic processing		 ISO
EXP		 Omeprazole affects the expression of NR1I3 mRNA
Omeprazole results in increased expression of NR1I3 mRNA
NR1I3 gene mutant form results in decreased metabolism of Omeprazole		 CTD PMID:19118567 PMID:19483382 PMID:27434302 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Omeprazole affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Oaf out at first homolog affects expression ISO Omeprazole affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 9:43,132,575...43,151,113
Ensembl chr 9:43,132,532...43,151,208 		JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) affects expression ISO Omeprazole affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642 		JBrowse link
G Or51e2 olfactory receptor family 51 subfamily E member 2 affects expression ISO Omeprazole affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678 		JBrowse link
G Ostc oligosaccharyltransferase complex subunit (non-catalytic) affects expression ISO Omeprazole affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 3:130,489,566...130,503,093
Ensembl chr 3:130,489,561...130,503,093 		JBrowse link
G Otc ornithine transcarbamylase affects expression ISO Omeprazole affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263 		JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression ISO Omeprazole affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 4:123,172,722...123,192,718
Ensembl chr 4:123,156,144...123,192,718 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase affects expression ISO Omeprazole affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr 5:77,099,149...77,115,356
Ensembl chr 5:77,099,154...77,115,356 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO Omeprazole results in increased cleavage of PARP1 protein CTD PMID:15461867 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pccb propionyl Coenzyme A carboxylase, beta polypeptide affects expression ISO Omeprazole affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 9:100,864,085...100,916,993
Ensembl chr 9:100,864,085...100,916,951 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP		 [Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein]
Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]		 CTD PMID:19251492 PMID:26970604 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression ISO Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134 		JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression ISO Omeprazole affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr11:89,873,370...89,893,720
Ensembl chr11:89,873,491...89,893,720 		JBrowse link
G Pcx pyruvate carboxylase affects expression ISO Omeprazole affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780 		JBrowse link
G Pdcl3 phosducin-like 3 affects expression ISO Omeprazole affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 1:39,026,895...39,036,317
Ensembl chr 1:39,024,689...39,036,319 		JBrowse link
G Pdia3 protein disulfide isomerase associated 3 affects expression ISO Omeprazole affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168 		JBrowse link
G Pdia6 protein disulfide isomerase associated 6 affects expression ISO Omeprazole affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771 		JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression ISO Omeprazole affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr 1:171,954,322...171,964,064
Ensembl chr 1:171,954,322...171,964,060 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression ISO Omeprazole affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression ISO Omeprazole affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:35,861,846...35,869,732
Ensembl chr  X:35,861,859...35,869,732 		JBrowse link
G Phyh phytanoyl-CoA hydroxylase affects expression ISO Omeprazole affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr 2:4,923,807...4,943,554
Ensembl chr 2:4,923,830...4,943,541 		JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression ISO Omeprazole affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr16:94,159,622...94,171,874
Ensembl chr16:94,159,622...94,172,701 		JBrowse link
G Pklr pyruvate kinase liver and red blood cell affects expression ISO Omeprazole affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) increases phosphorylation
multiple interactions		 ISO Omeprazole results in increased phosphorylation of PLA2G4A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]		 CTD PMID:25797602 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression ISO Omeprazole affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 6:136,589,069...136,639,301
Ensembl chr 6:136,589,068...136,638,926 		JBrowse link
G Plg plasminogen affects expression ISO Omeprazole affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Pls3 plastin 3 (T-isoform) affects expression ISO Omeprazole affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:74,829,259...74,918,788
Ensembl chr  X:74,829,260...74,918,788 		JBrowse link
G Pon2 paraoxonase 2 affects expression ISO Omeprazole affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455 		JBrowse link
G Pou2f2 POU domain, class 2, transcription factor 2 multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein] CTD PMID:30452898 NCBI chr 7:24,790,111...24,879,292
Ensembl chr 7:24,786,769...24,879,151 		JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression ISO Omeprazole affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 2:180,828,615...180,830,297
Ensembl chr 2:180,829,040...180,830,564 		JBrowse link
G Prdx2 peroxiredoxin 2 affects expression ISO Omeprazole affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463 		JBrowse link
G Prdx6 peroxiredoxin 6 affects expression ISO Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Prl prolactin increases expression ISO Omeprazole results in increased expression of PRL protein CTD PMID:20726208 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188 		JBrowse link
G Proc protein C affects expression ISO Omeprazole affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression ISO Omeprazole affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr11:116,361,641...116,385,739
Ensembl chr11:116,361,671...116,385,461 		JBrowse link
G Psma6 proteasome subunit alpha 6 affects expression ISO Omeprazole affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr12:55,431,007...55,465,244
Ensembl chr12:55,431,007...55,465,239 		JBrowse link
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 affects expression ISO Omeprazole affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013 		JBrowse link
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 affects expression ISO Omeprazole affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr11:97,594,260...97,604,326
Ensembl chr11:97,594,225...97,604,326 		JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 affects expression ISO Omeprazole affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664 		JBrowse link
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 affects expression ISO Omeprazole affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 2:90,884,361...90,889,783
Ensembl chr 2:90,884,354...90,896,714 		JBrowse link
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 affects expression ISO Omeprazole affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946 		JBrowse link
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 affects expression ISO Omeprazole affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 1:85,992,341...86,067,017
Ensembl chr 1:85,992,109...86,066,873 		JBrowse link
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 affects expression ISO Omeprazole affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP		 [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein
Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]		 CTD PMID:23038005 PMID:26970604 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptms parathymosin affects expression ISO Omeprazole affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066 		JBrowse link
G Ptprf protein tyrosine phosphatase receptor type F affects expression ISO Omeprazole affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602 		JBrowse link
G Pttg1ip pituitary tumor-transforming 1 interacting protein affects expression ISO Omeprazole affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr10:77,417,489...77,434,566
Ensembl chr10:77,417,554...77,434,566 		JBrowse link
G Pygl liver glycogen phosphorylase affects expression ISO Omeprazole affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262 		JBrowse link
G Rab5if RAB5 interacting factor affects expression ISO Omeprazole affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 2:156,705,042...156,715,483
Ensembl chr 2:156,705,048...156,715,483 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]
Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]		 CTD PMID:19251492 PMID:30452898 PMID:32418911 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Retsat retinol saturase (all trans retinol 13,14 reductase) increases expression ISO Omeprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 6:72,575,585...72,584,471
Ensembl chr 6:72,575,458...72,585,408 		JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression ISO Omeprazole affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401 		JBrowse link
G Rnase4 ribonuclease, RNase A family 4 affects expression ISO Omeprazole affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr14:51,328,534...51,343,608
Ensembl chr14:51,328,534...51,343,608 		JBrowse link
G Rnf103 ring finger protein 103 affects expression ISO Omeprazole affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 6:71,470,828...71,487,864
Ensembl chr 6:71,470,878...71,487,865 		JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression ISO Omeprazole affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr17:24,633,620...24,644,872
Ensembl chr17:24,633,539...24,644,875 		JBrowse link
G Rpl11 ribosomal protein L11 affects expression ISO Omeprazole affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 4:135,776,665...135,780,704
Ensembl chr 4:135,755,576...135,780,739 		JBrowse link
G Rpl13 ribosomal protein L13 affects expression ISO Omeprazole affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr 8:123,829,089...123,831,983
Ensembl chr 8:123,829,089...123,831,983 		JBrowse link
G Rpl15 ribosomal protein L15 affects expression ISO Omeprazole affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr14:4,198,710...4,201,873
Ensembl chr14:4,198,305...4,201,873 		JBrowse link
G Rpl17 ribosomal protein L17 affects expression ISO Omeprazole affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:75,132,049...75,136,455
Ensembl chr18:75,131,629...75,136,452 		JBrowse link
G Rpl23 ribosomal protein L23 affects expression ISO Omeprazole affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr11:97,668,352...97,673,265
Ensembl chr11:97,668,353...97,673,263 		JBrowse link
G Rpl3 ribosomal protein L3 affects expression ISO Omeprazole affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr15:79,961,993...79,967,553
Ensembl chr15:79,961,992...79,976,069 		JBrowse link
G Rpl32 ribosomal protein L32 affects expression ISO Omeprazole affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 6:115,782,475...115,785,704
Ensembl chr 6:115,782,466...115,785,708 		JBrowse link
G Rpl4 ribosomal protein L4 affects expression ISO Omeprazole affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 9:64,080,159...64,085,805
Ensembl chr 9:64,080,657...64,085,948 		JBrowse link
G Rpn2 ribophorin II affects expression ISO Omeprazole affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 2:157,121,018...157,168,238
Ensembl chr 2:157,120,937...157,168,239 		JBrowse link
G Rps14 ribosomal protein S14 affects expression ISO Omeprazole affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:60,907,668...60,911,618
Ensembl chr18:60,880,170...60,911,618 		JBrowse link
G Rps18 ribosomal protein S18 affects expression ISO Omeprazole affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr17:34,170,972...34,174,639
Ensembl chr17:34,170,973...34,174,975 		JBrowse link
G Rps19 ribosomal protein S19 affects expression ISO Omeprazole affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 7:24,584,013...24,589,236
Ensembl chr 7:24,583,796...24,589,231 		JBrowse link
G Rps20 ribosomal protein S20 affects expression ISO Omeprazole affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 4:3,831,334...3,835,600
Ensembl chr 4:3,831,334...3,835,665 		JBrowse link
G Rps3a1 ribosomal protein S3A1 affects expression ISO Omeprazole affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 3:86,045,247...86,049,975
Ensembl chr 3:86,045,247...86,050,009 		JBrowse link
G Rps6 ribosomal protein S6 affects expression ISO Omeprazole affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649 		JBrowse link
G Rps8 ribosomal protein S8 affects expression ISO Omeprazole affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 4:117,011,033...117,013,329
Ensembl chr 4:117,011,024...117,013,440 		JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 affects expression ISO Omeprazole affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression ISO Omeprazole affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721 		JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression ISO Omeprazole affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 1:15,924,086...15,962,946
Ensembl chr 1:15,924,086...15,962,946 		JBrowse link
G Sdc2 syndecan 2 affects expression ISO Omeprazole affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081 		JBrowse link
G Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein affects expression ISO Omeprazole affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr 1:170,956,726...170,978,209
Ensembl chr 1:170,954,734...170,978,172 		JBrowse link
G Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein affects expression ISO Omeprazole affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 9:50,507,640...50,515,149
Ensembl chr 9:50,507,657...50,515,112 		JBrowse link
G Sell selectin, lymphocyte decreases expression ISO Omeprazole results in decreased expression of SELL protein CTD PMID:17652263 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Serinc3 serine incorporator 3 affects expression ISO Omeprazole affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 2:163,466,577...163,487,767
Ensembl chr 2:163,465,192...163,487,051 		JBrowse link
G Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 affects expression ISO Omeprazole affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr12:103,582,934...103,597,681
Ensembl chr12:103,581,045...103,597,703 		JBrowse link
G Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 affects expression ISO Omeprazole affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983 		JBrowse link
G Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 affects expression ISO Omeprazole affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr11:75,322,562...75,330,327
Ensembl chr11:75,322,558...75,330,417 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 decreases expression ISO Omeprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Sfxn1 sideroflexin 1 affects expression ISO Omeprazole affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) affects expression ISO Omeprazole affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr10:127,352,992...127,358,313
Ensembl chr10:127,352,992...127,358,313 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 affects expression ISO Omeprazole affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 multiple interactions ISO Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine] CTD PMID:19041296 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486 		JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 multiple interactions ISO [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199 		JBrowse link
G Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 affects expression ISO Omeprazole affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:35,747,657...35,762,900
Ensembl chr18:35,747,657...35,760,297 		JBrowse link
G Slc25a13 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 affects expression ISO Omeprazole affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 6:6,041,218...6,217,304
Ensembl chr 6:6,041,218...6,217,173 		JBrowse link
G Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 affects expression ISO Omeprazole affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr10:90,952,436...90,959,902
Ensembl chr10:90,952,436...90,959,921 		JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 affects expression ISO Omeprazole affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163 		JBrowse link
G Slc39a8 solute carrier family 39 (metal ion transporter), member 8 affects expression ISO Omeprazole affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333 		JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 decreases expression EXP Omeprazole results in decreased expression of SLC40A1 protein CTD PMID:31669099 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683 		JBrowse link
G Slc46a1 solute carrier family 46, member 1 affects expression ISO Omeprazole affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr11:78,356,527...78,362,771
Ensembl chr11:78,356,523...78,362,885 		JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression ISO Omeprazole affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:80,298,458...80,335,940
Ensembl chr18:80,296,507...80,335,940 		JBrowse link
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 affects expression ISO Omeprazole affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047 		JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1a5 increases expression ISO Omeprazole results in increased expression of SLCO1A2 mRNA CTD PMID:19118567 NCBI chr 6:142,179,953...142,268,707
Ensembl chr 6:142,179,953...142,268,707 		JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein] CTD PMID:28849987 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sppl2a signal peptide peptidase like 2A affects expression ISO Omeprazole affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 2:126,732,311...126,775,706
Ensembl chr 2:126,732,311...126,775,155 		JBrowse link
G Srm spermidine synthase affects expression ISO Omeprazole affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450 		JBrowse link
G Srprb signal recognition particle receptor, B subunit affects expression ISO Omeprazole affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 9:103,065,232...103,079,264
Ensembl chr 9:103,065,231...103,079,336 		JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression ISO Omeprazole affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 3:146,110,397...146,145,899
Ensembl chr 3:146,110,397...146,145,899 		JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression ISO Omeprazole affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr16:58,290,105...58,344,614
Ensembl chr16:58,288,488...58,344,606 		JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 affects expression ISO Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100 		JBrowse link
G Suclg1 succinate-CoA ligase, GDP-forming, alpha subunit affects expression ISO Omeprazole affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 6:73,225,488...73,253,890
Ensembl chr 6:73,225,365...73,253,894 		JBrowse link
G Surf4 surfeit gene 4 affects expression ISO Omeprazole affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 2:26,810,052...26,823,801
Ensembl chr 2:26,810,052...26,823,940 		JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression ISO Omeprazole affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr12:81,538,968...81,579,685
Ensembl chr12:81,544,715...81,579,685 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions EXP Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Omeprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression ISO Omeprazole affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375 		JBrowse link
G Thnsl2 threonine synthase-like 2 (bacterial) affects expression ISO Omeprazole affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 6:71,105,150...71,121,364
Ensembl chr 6:71,105,150...71,121,423 		JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression ISO Omeprazole affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:84,964,316...84,970,168
Ensembl chr18:84,964,316...84,969,649 		JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 multiple interactions ISO Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein] CTD PMID:16934674 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566 		JBrowse link
G Tkfc triokinase, FMN cyclase affects expression ISO Omeprazole affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr19:10,565,153...10,583,257
Ensembl chr19:10,565,155...10,583,018 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein] CTD PMID:32418911 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression ISO Omeprazole affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 1:74,327,406...74,343,495
Ensembl chr 1:74,327,406...74,344,781 		JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression ISO Omeprazole affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr 1:167,136,239...167,161,547
Ensembl chr 1:167,135,947...167,161,547 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression ISO Omeprazole affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr 5:124,678,835...124,688,566
Ensembl chr 5:124,678,758...124,688,569 		JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression ISO Omeprazole affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:46,718,995...46,730,602
Ensembl chr18:46,693,302...46,730,602 		JBrowse link
G Tmem123 transmembrane protein 123 affects expression ISO Omeprazole affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 9:7,764,078...7,794,334
Ensembl chr 9:7,764,042...7,794,334 		JBrowse link
G Tmem97 transmembrane protein 97 affects expression ISO Omeprazole affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr11:78,432,643...78,441,561
Ensembl chr11:78,432,643...78,441,603 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]
Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]		 CTD PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Txn1 thioredoxin 1 affects expression ISO Omeprazole affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Txnl1 thioredoxin-like 1 affects expression ISO Omeprazole affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:63,795,872...63,825,535
Ensembl chr18:63,794,165...63,841,872 		JBrowse link
G Tyr tyrosinase multiple interactions
decreases expression		 ISO
EXP		 Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole results in decreased expression of TYR protein		 CTD PMID:25337692 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression ISO Omeprazole affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr 8:70,960,913...70,963,067
Ensembl chr 8:70,960,913...70,963,451 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression ISO Omeprazole affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER-associated degradation 1 affects expression ISO Omeprazole affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr16:18,630,486...18,654,011
Ensembl chr16:18,630,529...18,654,011 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases expression
affects expression		 ISO Omeprazole results in increased expression of UGT1A1 mRNA
Omeprazole affects the expression of UGT1A1 mRNA		 CTD PMID:19118567 PMID:19483382 PMID:25626140 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases expression ISO Omeprazole results in increased expression of UGT1A10 mRNA CTD PMID:19118567 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases expression ISO Omeprazole results in increased expression of UGT1A4 mRNA CTD PMID:19118567 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression
multiple interactions		 ISO Omeprazole results in increased expression of UGT1A6 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA		 CTD PMID:19118567 PMID:22687989 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases expression ISO Omeprazole results in increased expression of UGT1A9 mRNA CTD PMID:19118567 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression ISO Omeprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression ISO Omeprazole affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr10:80,238,831...80,242,655
Ensembl chr10:80,238,831...80,242,664 		JBrowse link
G Vnn1 vanin 1 affects expression ISO Omeprazole affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241 		JBrowse link
G Wdr26 WD repeat domain 26 affects expression ISO Omeprazole affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr 1:181,000,791...181,046,211
Ensembl chr 1:181,000,793...181,039,566 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide affects expression ISO Omeprazole affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr 5:135,937,233...135,963,495
Ensembl chr 5:135,937,263...135,963,470 		JBrowse link
G Zdhhc23 zinc finger, DHHC domain containing 23 affects expression ISO Omeprazole affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154 		JBrowse link
G Zp3r zona pellucida 3 receptor decreases expression
affects expression		 ISO Omeprazole results in decreased expression of C4BPA mRNA
Omeprazole affects the expression of C4BPA mRNA		 CTD PMID:19483382 PMID:25626140 NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358 		JBrowse link
G Zwint ZW10 interactor affects expression ISO Omeprazole affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr10:72,490,678...72,510,796
Ensembl chr10:72,490,677...72,510,796 		JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 multiple interactions EXP [CYP2C37 protein results in increased metabolism of Omeprazole] which results in increased chemical synthesis of 5-hydroxymethylomeprazole CTD PMID:30503582 NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    chemical entity 22306
      chemical substance 14877
        mixture 14101
          racemate 12407
            omeprazole 400
              5'-hydroxyomeprazole 2
              Yosprala 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22182
                    p-block element atom 22182
                      carbon group element atom 21984
                        carbon atom 21924
                          organic molecular entity 21924
                            organic molecule 21750
                              organic cyclic compound 21366
                                organic heterocyclic compound 20382
                                  organic heteropolycyclic compound 19675
                                    organic heterobicyclic compound 18253
                                      benzimidazoles 1182
                                        5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole 400
                                          esomeprazole 400
                                            omeprazole 400
                                              5'-hydroxyomeprazole 2
                                              Yosprala 0
paths to the root