Cxcr4 (chemokine (C-X-C motif) receptor 4) - Rat Genome Database

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Gene: Cxcr4 (chemokine (C-X-C motif) receptor 4) Mus musculus
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Symbol: Cxcr4
Name: chemokine (C-X-C motif) receptor 4
RGD ID: 732177
MGI Page MGI
Description: Predicted to enable several functions, including chemokine receptor activity; cytoskeletal protein binding activity; and ubiquitin protein ligase binding activity. Involved in myelin maintenance; positive regulation of cold-induced thermogenesis; and positive regulation of oligodendrocyte differentiation. Acts upstream of or within several processes, including circulatory system development; gamete generation; and nervous system development. Located in cell-cell junction; external side of plasma membrane; and growth cone. Is expressed in several structures, including alimentary system; cardiovascular system; embryo mesenchyme; extraembryonic component; and nervous system. Used to study WHIM syndrome. Human ortholog(s) of this gene implicated in WHIM syndrome; hematologic cancer (multiple); leukopenia; osteoporosis; and pancreatic adenocarcinoma. Orthologous to human CXCR4 (C-X-C motif chemokine receptor 4); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; hypoxia inducible factor pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1,4-phenylenediamine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b2b220C; b2b220Clo; C-X-C chemokine receptor type 4; CD184; chemokine (C-X-C) receptor 4; chemokine receptor 4; Cmka; Cmkar4; CXC-R4; CXCR-4; fu; fusin; LESTR; leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; PB-C; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; Sdf; SDF-1 receptor; Sdf1r; stromal cell-derived factor 1 receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,515,936 - 128,520,036 (-)NCBIGRCm39mm39
GRCm39 Ensembl1128,515,936 - 128,520,030 (-)Ensembl
GRCm381128,588,199 - 128,592,299 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,588,199 - 128,592,293 (-)EnsemblGRCm38mm10GRCm38
MGSCv371130,484,776 - 130,488,876 (-)NCBIGRCm37mm9NCBIm37
MGSCv361130,415,745 - 130,419,822 (-)NCBImm8
Celera1131,222,729 - 131,226,820 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-phenylenediamine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (EXP)
15-acetyldeoxynivalenol  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (ISO)
3-phenylprop-2-enal  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
acetamide  (ISO)
acrylonitrile  (ISO)
aflatoxin B1  (EXP,ISO)
alachlor  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-cyano-4-hydroxycinnamic acid  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
Bandrowski's base  (ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzyl bromide  (ISO)
beta-carotene  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
carfilzomib  (ISO)
chlordecone  (EXP)
chloroprene  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
cisatracurium  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
curcumin  (ISO)
cyclophosphamide  (EXP,ISO)
cylindrospermopsin  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
D-penicillamine  (ISO)
dapsone  (ISO)
daunorubicin  (ISO)
Deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
dichloromethane  (ISO)
dichromium trioxide  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP)
dihydro-beta-erythroidine  (ISO)
diisononyl phthalate  (EXP)
dinophysistoxin 1  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
erythromycin A  (EXP)
ethanol  (EXP)
ethylbenzene  (ISO)
etodolac  (ISO)
eugenol  (ISO)
ferric oxide  (EXP)
fingolimod hydrochloride  (ISO)
flavonoids  (ISO)
folic acid  (EXP,ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gallic acid  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
glucose  (EXP)
glyphosate  (ISO)
heparin  (ISO)
hexachlorobenzene  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lipopolysaccharide  (EXP)
mangiferin  (ISO)
Mecamylamine  (ISO)
mechlorethamine  (EXP)
mercury dibromide  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
miconazole  (EXP)
mifepristone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
naproxen  (ISO)
naringin  (ISO)
nickel atom  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicotine  (ISO)
nitric oxide  (EXP)
o-xylene  (ISO)
ochratoxin A  (ISO)
octadecanoic acid  (ISO)
oleandrin  (ISO)
omeprazole  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (ISO)
phenylmercury acetate  (ISO)
phosgene  (EXP)
picoxystrobin  (ISO)
picrotoxin  (ISO)
pioglitazone  (ISO)
piroxicam  (ISO)
plerixafor  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
probucol  (EXP)
progesterone  (ISO)
propanal  (ISO)
prostaglandin E2  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
sarin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sodium dodecyl sulfate  (ISO)
staurosporine  (ISO)
streptozocin  (ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
tamibarotene  (EXP,ISO)
tamoxifen  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetrathiomolybdate(2-)  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
thymoquinone  (EXP)
titanium dioxide  (EXP)
toluene  (ISO)
toluene 2,4-diisocyanate  (EXP)
tranilast  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
tungsten  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zalcitabine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ameboidal-type cell migration  (IMP)
animal organ morphogenesis  (TAS)
aorta development  (IMP)
brain development  (IBA,IMP)
branching involved in blood vessel morphogenesis  (IMP)
calcium-mediated signaling  (IBA,ISO)
cardiac muscle contraction  (ISO)
cell chemotaxis  (IBA)
cell migration  (ISO)
cellular response to cytokine stimulus  (IDA,ISO)
cellular response to xenobiotic stimulus  (ISO)
chemotaxis  (IEA)
CXCL12-activated CXCR4 signaling pathway  (IDA,ISO)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
endothelial cell differentiation  (ISO)
endothelial tube morphogenesis  (ISO)
epithelial cell development  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
generation of neurons  (IEP)
germ cell development  (IMP)
germ cell migration  (IMP)
hematopoietic stem cell migration  (IMP)
immune response  (IBA)
kidney development  (IMP)
motor neuron axon guidance  (IMP)
myelin maintenance  (IMP)
nervous system development  (TAS)
neural precursor cell proliferation  (IEP)
neurogenesis  (IBA,ISO)
neuron migration  (IDA,ISO)
neuron recognition  (ISO)
positive regulation of calcium ion import  (IDA)
positive regulation of cell migration  (ISO)
positive regulation of chemotaxis  (ISO)
positive regulation of cold-induced thermogenesis  (IMP)
positive regulation of cytosolic calcium ion concentration  (IBA)
positive regulation of dendrite extension  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IMP)
positive regulation of macrophage migration inhibitory factor signaling pathway  (ISO)
positive regulation of mesenchymal stem cell migration  (ISO)
positive regulation of neurogenesis  (ISO)
positive regulation of oligodendrocyte differentiation  (IMP)
positive regulation of protein phosphorylation  (IMP)
positive regulation of vascular wound healing  (ISO)
regulation of calcium ion transport  (ISO)
regulation of cell adhesion  (ISO)
regulation of cell migration  (IGI,IMP)
regulation of chemotaxis  (ISO)
regulation of programmed cell death  (ISO)
regulation of viral process  (ISO)
response to activity  (ISO)
response to hypoxia  (ISO)
response to morphine  (ISO)
response to organic cyclic compound  (ISO)
response to ultrasound  (ISO)
signal transduction  (IEA)
T cell proliferation  (IMP)
telencephalon cell migration  (ISO)
ventricular septum development  (IMP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal CD4-positive, alpha beta T cell number  (IAGP)
abnormal cell chemotaxis  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal developmental vascular remodeling  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart right ventricle outflow tract morphology  (IAGP)
abnormal immune system cell morphology  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal intrinsic tongue muscle morphology  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal leukopoiesis  (IAGP)
abnormal lymph node B cell domain morphology  (IAGP)
abnormal lymph node morphology  (IAGP)
abnormal lymphopoiesis  (IAGP)
abnormal macrophage cell number  (IAGP)
abnormal muscle precursor cell migration  (IAGP)
abnormal myogenesis  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neutrophil morphology  (IAGP)
abnormal NK cell physiology  (IAGP)
abnormal Peyer's patch follicle morphology  (IAGP)
abnormal primordial germ cell migration  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal thymus morphology  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal vasculogenesis  (IAGP)
absent cerebellar foliation  (IAGP)
aorta stenosis  (IEA)
aortic arch hypoplasia  (IEA)
aortic valve atresia  (IEA)
atelectasis  (IAGP)
decreased B cell apoptosis  (IAGP)
decreased B cell number  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased B-2 B cell number  (IAGP)
decreased body size  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased fetal size  (IAGP)
decreased immature B cell number  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased mammary gland tumor incidence in breeding females  (IAGP)
decreased mature B cell number  (IAGP)
decreased NK cell number  (IAGP)
decreased oxygen consumption  (IAGP)
decreased plasma cell number  (IAGP)
decreased primordial germ cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased spleen weight  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased susceptibility to Retroviridae infection  (IAGP)
decreased T cell number  (IAGP)
decreased thymocyte number  (IAGP)
decreased tongue size  (IAGP)
double aortic arch  (IEA)
duplex kidney  (IEA)
ectopic Purkinje cell  (IAGP)
failure of myelopoiesis  (IAGP)
hydronephrosis  (IEA)
hydrops fetalis  (IAGP)
hypaxial muscle hypoplasia  (IAGP)
impaired adaptive thermogenesis  (IAGP)
impaired myelopoiesis  (IAGP)
increased brown adipose tissue mass  (IAGP)
increased brown fat cell size  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased gonadal fat pad weight  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immunoglobulin level  (IAGP)
increased lymphocyte cell number  (IAGP)
increased mature B cell number  (IAGP)
increased mesenteric fat pad weight  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased NK cell number  (IAGP)
increased retroperitoneal fat pad weight  (IAGP)
increased subcutaneous adipose tissue amount  (IAGP)
increased susceptibility to diet-induced obesity  (IAGP)
increased susceptibility to Retroviridae infection induced morbidity/mortality  (IAGP)
increased total body fat amount  (IAGP)
increased white adipose tissue mass  (IAGP)
increased white fat cell size  (IAGP)
kidney hemorrhage  (IAGP)
kidney vascular congestion  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
muscular ventricular septal defect  (IEA)
neonatal lethality, complete penetrance  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polycystic kidney  (IEA)
poor arterial differentiation  (IAGP)
right aortic arch  (IEA)
small intestine hemorrhage  (IAGP)
thick mitral valve cusps  (IAGP)
thin external granule cell layer  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
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14. MGD data from the GO Consortium
15. MGD IEA
16. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
17. OMIM Disease Annotation Pipeline
18. Park B, etal., Int J Cancer. 2011 Jul 1;129(1):23-33. doi: 10.1002/ijc.25966. Epub 2011 Mar 29.
19. Pipeline to import KEGG annotations from KEGG into RGD
20. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
21. RGD automated import pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Roccaro AM, etal., Blood. 2014 Jun 26;123(26):4120-31. doi: 10.1182/blood-2014-03-564583. Epub 2014 Apr 7.
25. Sanghani A, etal., Tissue Eng Part A. 2018 Dec;24(23-24):1775-1783. doi: 10.1089/ten.TEA.2018.0121. Epub 2018 Sep 19.
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33. Zhou Z, etal., Behav Brain Res. 2017 Mar 30;322(Pt A):83-91. doi: 10.1016/j.bbr.2017.01.014. Epub 2017 Jan 16.
Additional References at PubMed
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PMID:10349636   PMID:10479460   PMID:10571666   PMID:11042159   PMID:11069075   PMID:11076861   PMID:11092979   PMID:11197687   PMID:11217851   PMID:11272281   PMID:11301003   PMID:11489951  
PMID:11520466   PMID:11983855   PMID:12126650   PMID:12477932   PMID:12583436   PMID:12684531   PMID:12705474   PMID:12707343   PMID:12714971   PMID:12730102   PMID:12805300   PMID:12832536  
PMID:12839981   PMID:12900445   PMID:12932359   PMID:14512296   PMID:14568925   PMID:14583470   PMID:14595012   PMID:14638861   PMID:14704365   PMID:15013630   PMID:15054039   PMID:15189736  
PMID:15240672   PMID:15300245   PMID:15304476   PMID:15489334   PMID:15505104   PMID:15520246   PMID:15533866   PMID:15542430   PMID:15574767   PMID:15608062   PMID:15626744   PMID:15647826  
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PMID:16166380   PMID:16170318   PMID:16198599   PMID:16210615   PMID:16230077   PMID:16254213   PMID:16262623   PMID:16291599   PMID:16302230   PMID:16387292   PMID:16390867   PMID:16424223  
PMID:16537807   PMID:16545793   PMID:16602821   PMID:16627256   PMID:16648859   PMID:16793890   PMID:16819978   PMID:16841089   PMID:16863905   PMID:16906157   PMID:16931623   PMID:16940167  
PMID:16964252   PMID:17010372   PMID:17114479   PMID:17148948   PMID:17158356   PMID:17174120   PMID:17182777   PMID:17360804   PMID:17374136   PMID:17379762   PMID:17463394   PMID:17507648  
PMID:17522382   PMID:17596540   PMID:17605079   PMID:17640962   PMID:17646584   PMID:17671223   PMID:17715292   PMID:17764962   PMID:17804806   PMID:17823289   PMID:17827391   PMID:17853408  
PMID:17878289   PMID:17889832   PMID:17925864   PMID:17971416   PMID:17971873   PMID:17976542   PMID:18031680   PMID:18037996   PMID:18040270   PMID:18086932   PMID:18184815   PMID:18188864  
PMID:18206727   PMID:18219852   PMID:18227060   PMID:18234887   PMID:18239145   PMID:18272682   PMID:18279715   PMID:18369102   PMID:18378795   PMID:18422759   PMID:18435916   PMID:18448648  
PMID:18464929   PMID:18495324   PMID:18579746   PMID:18588860   PMID:18606818   PMID:18617694   PMID:18678898   PMID:18765807   PMID:18791205   PMID:18799476   PMID:18805969   PMID:18827024  
PMID:18940728   PMID:19008373   PMID:19030180   PMID:19059110   PMID:19064997   PMID:19103804   PMID:19109194   PMID:19141863   PMID:19144663   PMID:19155474   PMID:19192873   PMID:19193877  
PMID:19220581   PMID:19248097   PMID:19252491   PMID:19264920   PMID:19281787   PMID:19285061   PMID:19286309   PMID:19299746   PMID:19322207   PMID:19357083   PMID:19384956   PMID:19386638  
PMID:19407239   PMID:19415696   PMID:19423843   PMID:19429788   PMID:19433312   PMID:19443644   PMID:19520808   PMID:19627512   PMID:19627984   PMID:19635473   PMID:19668217   PMID:19755795  
PMID:19758998   PMID:19762327   PMID:19777566   PMID:19780901   PMID:19820417   PMID:19821487   PMID:19859544   PMID:19898483   PMID:19955710   PMID:20003423   PMID:20007689   PMID:20007826  
PMID:20010845   PMID:20038597   PMID:20110411   PMID:20151462   PMID:20154215   PMID:20181837   PMID:20197403   PMID:20200107   PMID:20376365   PMID:20392955   PMID:20421491   PMID:20458749  
PMID:20484220   PMID:20498529   PMID:20516641   PMID:20524780   PMID:20534452   PMID:20534485   PMID:20557955   PMID:20572009   PMID:20634485   PMID:20651364   PMID:20660740   PMID:20681075  
PMID:20682445   PMID:20714873   PMID:20736301   PMID:20829512   PMID:20847314   PMID:20869949   PMID:20880358   PMID:20882566   PMID:20890042   PMID:20939892   PMID:20944068   PMID:20969841  
PMID:21035938   PMID:21046557   PMID:21059953   PMID:21106854   PMID:21124917   PMID:21131428   PMID:21143386   PMID:21150899   PMID:21165786   PMID:21168468   PMID:21173223   PMID:21187396  
PMID:21212101   PMID:21220099   PMID:21220100   PMID:21267068   PMID:21270405   PMID:21270460   PMID:21300888   PMID:21300913   PMID:21306303   PMID:21324162   PMID:21421844   PMID:21426925  
PMID:21440680   PMID:21460863   PMID:21502490   PMID:21537329   PMID:21553023   PMID:21618098   PMID:21622896   PMID:21636574   PMID:21671800   PMID:21684336   PMID:21685249   PMID:21719761  
PMID:21742774   PMID:21821779   PMID:21824737   PMID:21830237   PMID:21873635   PMID:21878648   PMID:21911833   PMID:21915267   PMID:21969590   PMID:22039399   PMID:22069486   PMID:22115649  
PMID:22121892   PMID:22232208   PMID:22265737   PMID:22276210   PMID:22277947   PMID:22342795   PMID:22345572   PMID:22370717   PMID:22421355   PMID:22432025   PMID:22438253   PMID:22532671  
PMID:22546945   PMID:22592891   PMID:22610174   PMID:22634622   PMID:22685115   PMID:22688512   PMID:22736769   PMID:22766125   PMID:22773586   PMID:22815687   PMID:22880115   PMID:22888250  
PMID:22902718   PMID:22956548   PMID:22967998   PMID:22984452   PMID:22987640   PMID:22992418   PMID:23018206   PMID:23091025   PMID:23133664   PMID:23183167   PMID:23212153   PMID:23224220  
PMID:23239029   PMID:23257686   PMID:23273785   PMID:23292680   PMID:23308188   PMID:23349789   PMID:23395391   PMID:23447624   PMID:23452257   PMID:23460741   PMID:23462453   PMID:23469143  
PMID:23474530   PMID:23484027   PMID:23485965   PMID:23497137   PMID:23509246   PMID:23525041   PMID:23528817   PMID:23620790   PMID:23669394   PMID:23682021   PMID:23684768   PMID:23690484  
PMID:23697661   PMID:23704087   PMID:23706740   PMID:23723373   PMID:23728080   PMID:23742988   PMID:23793062   PMID:23811810   PMID:23828719   PMID:23830865   PMID:23835861   PMID:23873382  
PMID:23881789   PMID:23884141   PMID:23916851   PMID:23929505   PMID:24026287   PMID:24081949   PMID:24091662   PMID:24101523   PMID:24154522   PMID:24157949   PMID:24174685   PMID:24184055  
PMID:24226205   PMID:24256728   PMID:24290754   PMID:24312539   PMID:24449842   PMID:24490172   PMID:24510783   PMID:24516532   PMID:24548137   PMID:24556683   PMID:24586749   PMID:24603431  
PMID:24646609   PMID:24695674   PMID:24718993   PMID:24723559   PMID:24742460   PMID:24752354   PMID:24760155   PMID:24790087   PMID:24808539   PMID:24816217   PMID:24876351   PMID:24898400  
PMID:24952961   PMID:24953490   PMID:24961298   PMID:24972797   PMID:24973450   PMID:25066162   PMID:25074471   PMID:25085881   PMID:25119456   PMID:25130304   PMID:25131778   PMID:25266175  
PMID:25268050   PMID:25403444   PMID:25425146   PMID:25460567   PMID:25474349   PMID:25482882   PMID:25502622   PMID:25513817   PMID:25537742   PMID:25562157   PMID:25572963   PMID:25647836  
PMID:25655934   PMID:25656357   PMID:25662009   PMID:25721302   PMID:25807483   PMID:25821988   PMID:25833331   PMID:25926459   PMID:25957946   PMID:25972253   PMID:26017770   PMID:26017771  
PMID:26029924   PMID:26058075   PMID:26058076   PMID:26085643   PMID:26133989   PMID:26159556   PMID:26190113   PMID:26246398   PMID:26261552   PMID:26265085   PMID:26274929   PMID:26396176  
PMID:26400936   PMID:26458529   PMID:26494786   PMID:26517693   PMID:26519029   PMID:26578388   PMID:26620267   PMID:26620723   PMID:26678086   PMID:26739213   PMID:26755698   PMID:26779814  
PMID:26798014   PMID:26841680   PMID:26883290   PMID:26892496   PMID:26965284   PMID:26967480   PMID:27002738   PMID:27005988   PMID:27030717   PMID:27052602   PMID:27068353   PMID:27121088  
PMID:27245949   PMID:27288704   PMID:27340788   PMID:27340942   PMID:27435625   PMID:27454381   PMID:27497284   PMID:27566567   PMID:27573814   PMID:27645115   PMID:27681431   PMID:27736296  
PMID:27811056   PMID:27841869   PMID:27863376   PMID:27868262   PMID:27886253   PMID:27986950   PMID:28052241   PMID:28087629   PMID:28092866   PMID:28148720   PMID:28213494   PMID:28264927  
PMID:28400375   PMID:28445180   PMID:28450349   PMID:28461496   PMID:28506990   PMID:28542132   PMID:28550161   PMID:28552733   PMID:28687617   PMID:28698642   PMID:28714968   PMID:28717168  
PMID:28720830   PMID:28887018   PMID:29016745   PMID:29031500   PMID:29084951   PMID:29093284   PMID:29232699   PMID:29240767   PMID:29275859   PMID:29396162   PMID:29398651   PMID:29427452  
PMID:29466759   PMID:29533926   PMID:29688375   PMID:29715199   PMID:29734748   PMID:29783989   PMID:29879109   PMID:29934471   PMID:30010038   PMID:30087351   PMID:30105642   PMID:30271956  
PMID:30282719   PMID:30355939   PMID:30359311   PMID:30359325   PMID:30372748   PMID:30377227   PMID:30397255   PMID:30408103   PMID:30422351   PMID:30451884   PMID:30470704   PMID:30595537  
PMID:30656691   PMID:30678736   PMID:30707456   PMID:30709741   PMID:30726732   PMID:30733468   PMID:30738798   PMID:30850578   PMID:30853441   PMID:30870116   PMID:30950188   PMID:30958662  
PMID:30992469   PMID:31071921   PMID:31189656   PMID:31211835   PMID:31477919   PMID:31669249   PMID:31679624   PMID:31687976   PMID:31693895   PMID:31712428   PMID:31845480   PMID:31852686  
PMID:31921208   PMID:31931030   PMID:31932813   PMID:31985098   PMID:32027977   PMID:32042176   PMID:32159901   PMID:32181567   PMID:32193486   PMID:32242005   PMID:32281218   PMID:32330088  
PMID:32418119   PMID:32418467   PMID:32606001   PMID:32659786   PMID:32661868   PMID:32678266   PMID:32683420   PMID:32708917   PMID:32783932   PMID:32945380   PMID:32974338   PMID:33003308  
PMID:33098771   PMID:33413641   PMID:33414275   PMID:33435128   PMID:33454003   PMID:33469015   PMID:33470495   PMID:33693593   PMID:33804745   PMID:33942933   PMID:34335979   PMID:34350830  


Genomics

Comparative Map Data
Cxcr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,515,936 - 128,520,036 (-)NCBIGRCm39mm39
GRCm39 Ensembl1128,515,936 - 128,520,030 (-)Ensembl
GRCm381128,588,199 - 128,592,299 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,588,199 - 128,592,293 (-)EnsemblGRCm38mm10GRCm38
MGSCv371130,484,776 - 130,488,876 (-)NCBIGRCm37mm9NCBIm37
MGSCv361130,415,745 - 130,419,822 (-)NCBImm8
Celera1131,222,729 - 131,226,820 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.43NCBI
CXCR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2136,114,349 - 136,118,149 (-)EnsemblGRCh38hg38GRCh38
GRCh382136,114,349 - 136,118,149 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372136,871,919 - 136,875,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,588,389 - 136,592,195 (-)NCBINCBI36hg18NCBI36
Build 342136,705,651 - 136,709,457NCBI
Celera2130,582,637 - 130,586,442 (-)NCBI
Cytogenetic Map2q22.1NCBI
HuRef2128,864,423 - 128,868,228 (-)NCBIHuRef
CHM1_12136,877,321 - 136,881,126 (-)NCBICHM1_1
Cxcr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21340,077,976 - 40,081,883 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1340,077,976 - 40,081,883 (-)Ensembl
Rnor_6.01345,314,952 - 45,318,856 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1345,314,933 - 45,318,878 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01350,394,128 - 50,398,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41341,308,286 - 41,312,190 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11341,322,328 - 41,326,213 (-)NCBI
Celera1340,447,190 - 40,451,093 (-)NCBICelera
Cytogenetic Map13q13NCBI
Cxcr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554403,455,153 - 3,460,109 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554403,456,165 - 3,460,024 (-)NCBIChiLan1.0ChiLan1.0
CXCR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B140,185,803 - 140,189,626 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B140,181,829 - 140,189,647 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B23,744,271 - 23,748,106 (+)NCBIMhudiblu_PPA_v0panPan3
CXCR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,874,650 - 38,877,740 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1938,874,145 - 38,877,740 (-)EnsemblCanFam3.1canFam3CanFam3.1
Cxcr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303101,819,271 - 101,823,136 (-)NCBI
SpeTri2.0NW_00493646939,794,613 - 39,798,448 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1515,663,494 - 15,667,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11515,663,652 - 15,666,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21518,125,415 - 18,128,469 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXCR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11020,336,470 - 20,340,308 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1020,336,247 - 20,340,309 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660612,116,532 - 2,120,394 (+)NCBIVero_WHO_p1.0
Cxcr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473235,473,740 - 35,477,482 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
PMC124533P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,589,380 - 128,589,619UniSTSGRCm38
MGSCv371130,485,957 - 130,486,196UniSTSGRCm37
Celera1131,223,902 - 131,224,141UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
PMC151816P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,588,397 - 128,588,620UniSTSGRCm38
MGSCv371130,484,974 - 130,485,197UniSTSGRCm37
Celera1131,222,923 - 131,223,146UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
PMC154343P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,589,730 - 128,589,806UniSTSGRCm38
MGSCv371130,486,307 - 130,486,383UniSTSGRCm37
Celera1131,224,252 - 131,224,328UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
PMC310750P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,589,311 - 128,589,790UniSTSGRCm38
MGSCv371130,485,888 - 130,486,367UniSTSGRCm37
Celera1131,223,833 - 131,224,312UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
Cxcr4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371130,485,642 - 130,486,052UniSTSGRCm37
MGSCv371130,485,135 - 130,485,657UniSTSGRCm37
MGSCv371130,485,661 - 130,485,902UniSTSGRCm37
Celera1131,223,587 - 131,223,997UniSTS
Celera1131,223,606 - 131,223,847UniSTS
Celera1131,223,084 - 131,223,602UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
Cmkar4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,588,531 - 128,588,760UniSTSGRCm38
MGSCv371130,485,108 - 130,485,337UniSTSGRCm37
Celera1131,223,057 - 131,223,286UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.4UniSTS
Cxcr4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,589,065 - 128,589,475UniSTSGRCm38
MGSCv371130,485,642 - 130,486,052UniSTSGRCm37
Celera1131,223,587 - 131,223,997UniSTS
Cytogenetic Map1E4UniSTS
Cxcr4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,589,084 - 128,589,325UniSTSGRCm38
MGSCv371130,485,661 - 130,485,902UniSTSGRCm37
Celera1131,223,606 - 131,223,847UniSTS
Cytogenetic Map1E4UniSTS
Cxcr4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381128,588,558 - 128,589,080UniSTSGRCm38
MGSCv371130,485,135 - 130,485,657UniSTSGRCm37
Celera1131,223,084 - 131,223,602UniSTS
Cytogenetic Map1E4UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)176000000128600000Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194200000148900000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196690656130690827Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197126256131126460Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199579930133580115Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1103040804137040937Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109568206143568206Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109710525143710742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110625442144625561Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110625442144625561Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112203268146203348Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116363098150363199Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118171982152172078Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121800000139800000Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121800000153900000Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121800000154000000Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1123000000157000000Mouse
1301488Tir3b_mtrypansomiasis infection response 3b (mouse)Not determined1128551097157361794Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir150mmu-miR-150-5pMirecordsexternal_infoNANA22039399
Mir224mmu-miR-224-5pOncomiRDBexternal_infoNANA20023705
Mir139mmu-miR-139-5pOncomiRDBexternal_infoNANA21925125
Mir302ammu-miR-302a-3pOncomiRDBexternal_infoNANA21720384
Mir146mmu-miR-146a-5pOncomiRDBexternal_infoNANA20023696

Predicted Target Of
Summary Value
Count of predictions:322
Count of miRNA genes:281
Interacting mature miRNAs:301
Transcripts:ENSMUST00000052172, ENSMUST00000142893
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB000803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB872868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF662224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF101560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U59760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U65580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z80111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z80112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z80113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000052172   ⟹   ENSMUSP00000053489
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1128,515,936 - 128,520,027 (-)Ensembl
GRCm38.p6 Ensembl1128,588,199 - 128,592,290 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142893   ⟹   ENSMUSP00000120153
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1128,516,836 - 128,520,030 (-)Ensembl
GRCm38.p6 Ensembl1128,589,099 - 128,592,293 (-)Ensembl
RefSeq Acc Id: NM_001356509   ⟹   NP_001343438
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391128,515,936 - 128,520,036 (-)NCBI
GRCm381128,588,199 - 128,592,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009911   ⟹   NP_034041
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391128,515,936 - 128,520,036 (-)NCBI
GRCm381128,588,199 - 128,592,299 (-)NCBI
MGSCv371130,484,776 - 130,488,876 (-)RGD
Celera1131,222,729 - 131,226,820 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529114   ⟹   XP_006529177
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391128,515,936 - 128,518,781 (-)NCBI
GRCm381128,588,199 - 128,590,725 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157035   ⟹   XP_036012928
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391128,515,936 - 128,519,516 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_034041   ⟸   NM_009911
- Peptide Label: isoform 1
- UniProtKB: P70658 (UniProtKB/Swiss-Prot),   A0A0R4J0N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529177   ⟸   XM_006529114
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001343438   ⟸   NM_001356509
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000053489   ⟸   ENSMUST00000052172
RefSeq Acc Id: ENSMUSP00000120153   ⟸   ENSMUST00000142893
RefSeq Acc Id: XP_036012928   ⟸   XM_036157035
- Peptide Label: isoform X2
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:6874808
Promoter ID:EPDNEW_M855
Type:multiple initiation site
Name:Cxcr4_1
Description:Mus musculus chemokine (C-X-C motif) receptor 4 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381128,592,299 - 128,592,359EPDNEW
RGD ID:6817568
Promoter ID:MM_KWN:1981
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   Lung,   Spleen
Transcripts:NM_009911,   UC007CLS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361130,488,691 - 130,489,742 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109563 AgrOrtholog
Ensembl Genes ENSMUSG00000045382 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000053489 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000120153 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052172 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000142893 UniProtKB/TrEMBL
InterPro Chemokine_CXCR4_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXCR4/ACKR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12767 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:109563 ENTREZGENE
NCBI Gene 12767 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXCR4_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CXCR4 RGD
PhenoGen Cxcr4 PhenoGen
PRINTS CCCHEMOKINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXCCHMKINER4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0N8 ENTREZGENE, UniProtKB/TrEMBL
  A1E2I3_MOUSE UniProtKB/TrEMBL
  CXCR4_MOUSE UniProtKB/Swiss-Prot
  E9Q2D4_MOUSE UniProtKB/TrEMBL
  P70658 ENTREZGENE
UniProt Secondary O09059 UniProtKB/Swiss-Prot
  O09062 UniProtKB/Swiss-Prot
  P70233 UniProtKB/Swiss-Prot
  P70346 UniProtKB/Swiss-Prot
  Q4KMW1 UniProtKB/Swiss-Prot