CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole
Accession: CHEBI:77260
browse the term
Definition: A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Synonyms: related_synonym: Formula=C17H19N3O3S; InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20); InChIKey=SUBDBMMJDZJVOS-UHFFFAOYSA-N; SMILES=COc1ccc2[nH]c(nc2c1)S(=O)Cc1ncc(C)c(OC)c1C
xref: CAS:73590-58-6; KEGG:C07324; KEGG:D00455
xref_mesh: MESH:D009853
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Abca1
ATP binding cassette subfamily A member 1
increases expression
ISO
Omeprazole results in increased expression of ABCA1 mRNA
CTD
PMID:20060385
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity
ISO
Omeprazole results in decreased activity of ABCB11 protein
CTD
PMID:20829430
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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Abcb1a
ATP binding cassette subfamily B member 1A
affects expression multiple interactions
EXP ISO
Omeprazole affects the expression of ABCB1A mRNA Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein] Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
CTD
PMID:19483382 PMID:30452898
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abcb4
ATP binding cassette subfamily B member 4
decreases expression
ISO
Omeprazole results in decreased expression of ABCB4 mRNA
CTD
PMID:12040753
NCBI chr 4:26,106,895...26,164,440
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Abcc2
ATP binding cassette subfamily C member 2
multiple interactions
ISO
[Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein
CTD
PMID:35447140
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
Omeprazole results in increased expression of ABCC3 mRNA
CTD
PMID:19118567
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Omeprazole affects the expression of ABCC6 mRNA
CTD
PMID:19483382
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
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Abcg2
ATP binding cassette subfamily G member 2
increases expression multiple interactions
ISO
Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]
CTD
PMID:20804740 PMID:31348918
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
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Abcg5
ATP binding cassette subfamily G member 5
affects expression
EXP
Omeprazole affects the expression of ABCG5 mRNA
CTD
PMID:19483382
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
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Abhd1
abhydrolase domain containing 1
affects expression
EXP
Omeprazole affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:31,142,476...31,147,464
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Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Omeprazole affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Omeprazole affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,775,016...9,781,447
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Acaca
acetyl-CoA carboxylase alpha
affects expression
EXP
Omeprazole affects the expression of ACACA mRNA
CTD
PMID:19483382
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
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Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Omeprazole affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:75,783,689...75,822,164
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Ace2
angiotensin converting enzyme 2
decreases expression
ISO EXP
Omeprazole results in decreased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
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Aco1
aconitase 1
affects expression
EXP
Omeprazole affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:60,055,866...60,112,600
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Aco2
aconitase 2
affects expression
EXP
Omeprazole affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:115,265,791...115,308,892
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Acot12
acyl-CoA thioesterase 12
affects expression
EXP
Omeprazole affects the expression of ACOT12 mRNA
CTD
PMID:19483382
NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298
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Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Omeprazole affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
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Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Omeprazole affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
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Add1
adducin 1
affects expression
EXP
Omeprazole affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
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Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
decreases expression
ISO
Omeprazole results in decreased expression of ADH1C mRNA
CTD
PMID:12040753
NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Omeprazole affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
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Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Omeprazole affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:23,135,809...23,216,622
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Afm
afamin
affects expression
EXP
Omeprazole affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
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Agt
angiotensinogen
affects expression
EXP
Omeprazole affects the expression of AGT mRNA
CTD
PMID:19483382
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Omeprazole affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
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Ahr
aryl hydrocarbon receptor
multiple interactions decreases activity increases activity increases expression decreases expression affects localization increases response to substance
EXP ISO
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein] Omeprazole results in decreased activity of AHR protein Omeprazole results in increased activity of AHR protein Omeprazole results in increased expression of AHR protein Omeprazole results in decreased expression of AHR mRNA AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein] Omeprazole affects the localization of AHR protein AHR protein results in increased susceptibility to Omeprazole
CTD
PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 PMID:21703235 PMID:21861773 PMID:21924250 PMID:22687989 PMID:23850985 PMID:25797602 PMID:25826687 PMID:26187274 PMID:26272953 PMID:31669099 More...
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Omeprazole affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
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Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Omeprazole affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
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Akr7a3
aldo-keto reductase family 7 member A3
affects expression multiple interactions
EXP
Omeprazole affects the expression of AKR7A3 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression multiple interactions
EXP
Omeprazole affects the expression of ALDH1A1 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
Omeprazole results in increased expression of ALDH1A3 mRNA
CTD
PMID:12040753
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
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Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
affects expression
EXP
Omeprazole affects the expression of ALDH1A7 mRNA
CTD
PMID:19483382
NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:227,627,448...227,672,523
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Omeprazole affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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Aldh3a1
aldehyde dehydrogenase 3 family, member A1
increases expression
ISO
Omeprazole results in increased expression of ALDH3A1 mRNA
CTD
PMID:12040753
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
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Alkbh7
alkB homolog 7
affects expression
EXP
Omeprazole affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
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Ankrd40
ankyrin repeat domain 40
increases expression
EXP
Omeprazole results in increased expression of TMPRSS2 mRNA
CTD
PMID:32808185
NCBI chr10:79,778,966...79,792,212
Ensembl chr10:56,415,260...56,416,345 Ensembl chr10:56,415,260...56,416,345
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Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Omeprazole affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
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Apcs
amyloid P component, serum
affects expression
EXP
Omeprazole affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
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Apoa4
apolipoprotein A4
affects expression
EXP
Omeprazole affects the expression of APOA4 mRNA
CTD
PMID:19483382
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
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Apoh
apolipoprotein H
affects expression
EXP
Omeprazole affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
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Apool
apolipoprotein O-like
affects expression
EXP
Omeprazole affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:81,569,960...81,635,906
Ensembl chr X:81,570,053...81,640,036
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Arg1
arginase 1
affects expression
EXP
Omeprazole affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
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Arl6ip1
ARL6 interacting reticulophagy regulator 1
affects expression
EXP
Omeprazole affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
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Arnt
aryl hydrocarbon receptor nuclear translocator
multiple interactions affects localization
ISO EXP
Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter] Omeprazole affects the localization of ARNT protein Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
CTD
PMID:9395520 PMID:21703235 PMID:25826687
NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
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Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Omeprazole affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
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Atf5
activating transcription factor 5
affects expression
EXP
Omeprazole affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
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Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Omeprazole affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
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Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Omeprazole affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Omeprazole affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Omeprazole affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:59,033,020...59,035,980
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Atp7a
ATPase copper transporting alpha
multiple interactions
ISO
Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
CTD
PMID:25337692
NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093
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Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Omeprazole affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein]
CTD
PMID:30452898
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]
CTD
PMID:30452898
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Omeprazole affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
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Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Omeprazole affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083
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Bmf
Bcl2 modifying factor
affects expression
EXP
Omeprazole affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
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Bmx
BMX non-receptor tyrosine kinase
multiple interactions
ISO
BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]
CTD
PMID:21861773
NCBI chr X:30,227,251...30,290,015
Ensembl chr X:33,859,129...33,921,874
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Bnip3
BCL2 interacting protein 3
affects expression
EXP
Omeprazole affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
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Btf3
basic transcription factor 3
affects expression
EXP
Omeprazole affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125 Ensembl chr13:31,394,011...31,401,125
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C1qa
complement C1q A chain
decreases expression
EXP
Omeprazole results in decreased expression of C1QA mRNA
CTD
PMID:25626140
NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
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C1qbp
complement C1q binding protein
affects expression
EXP
Omeprazole affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
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C1qc
complement C1q C chain
decreases expression
EXP
Omeprazole results in decreased expression of C1QC mRNA
CTD
PMID:25626140
NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
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C1s
complement C1s
affects expression
EXP
Omeprazole affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
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C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Omeprazole affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:50,694,563...50,759,016
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C4bpa
complement component 4 binding protein, alpha
affects expression decreases expression
EXP
Omeprazole affects the expression of C4BPA mRNA Omeprazole results in decreased expression of C4BPA mRNA
CTD
PMID:19483382 PMID:25626140
NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
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C4bpb
complement component 4 binding protein, beta
decreases expression
EXP
Omeprazole results in decreased expression of C4BPB mRNA
CTD
PMID:25626140
NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
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C7
complement C7
affects expression
EXP
Omeprazole affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
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C8b
complement C8 beta chain
affects expression
EXP
Omeprazole affects the expression of C8B mRNA
CTD
PMID:19483382
NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
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Ca3
carbonic anhydrase 3
affects expression
EXP
Omeprazole affects the expression of CAR3 mRNA
CTD
PMID:19483382
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
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Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Omeprazole affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
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Caprin1
cell cycle associated protein 1
affects expression
EXP
Omeprazole affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
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Car2
carbonic anhydrase 2
affects expression
EXP
Omeprazole affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
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Casp3
caspase 3
increases activity multiple interactions affects expression increases cleavage
ISO EXP
Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] Omeprazole affects the expression of CASP3 mRNA Omeprazole results in increased cleavage of CASP3 protein
CTD
PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 PMID:30452898 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp8
caspase 8
increases cleavage
ISO
Omeprazole analog results in increased cleavage of CASP8 protein
CTD
PMID:18336733
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Cat
catalase
increases activity multiple interactions
EXP ISO
Omeprazole results in increased activity of CAT protein Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein] Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein]
CTD
PMID:18547560 PMID:28849987 PMID:33245926
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Cbr1
carbonyl reductase 1
affects expression
EXP
Omeprazole affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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Cckbr
cholecystokinin B receptor
multiple interactions
ISO
[Omeprazole co-treated with CCKBR protein] results in increased expression of IER3
CTD
PMID:17704804
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:169,183,194...169,193,745
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Ccnd1
cyclin D1
decreases expression
EXP
Omeprazole results in decreased expression of CCND1 mRNA
CTD
PMID:17202759
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Omeprazole results in increased expression of CDKN1A protein
CTD
PMID:27358234
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Omeprazole affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
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Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Omeprazole affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:196,681,681...196,723,812
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Ces2h
carboxylesterase 2H
affects expression
EXP
Omeprazole affects the expression of CES2 mRNA
CTD
PMID:19483382
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
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Cfi
complement factor I
affects expression decreases expression
EXP
Omeprazole affects the expression of CFI mRNA Omeprazole results in decreased expression of CFI mRNA
CTD
PMID:19483382 PMID:25626140
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
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Cftr
CF transmembrane conductance regulator
affects metabolic processing
ISO
CFTR protein affects the metabolism of Omeprazole
CTD
PMID:15319328
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
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Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Omeprazole affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
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Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Omeprazole affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042
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Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Omeprazole affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:27,290,868...27,356,939
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Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Omeprazole affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,918,682...1,924,705
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Clptm1l
CLPTM1-like
affects expression
EXP
Omeprazole affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077
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Cmbl
carboxymethylenebutenolidase homolog
affects expression
EXP
Omeprazole affects the expression of CMBL mRNA
CTD
PMID:19483382
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:84,242,512...84,301,880
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Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Omeprazole affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596
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Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Omeprazole affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812
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Cops4
COP9 signalosome subunit 4
affects expression
EXP
Omeprazole affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,382,900...9,413,107
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Coq3
coenzyme Q3 methyltransferase
affects expression
EXP
Omeprazole affects the expression of COQ3 mRNA
CTD
PMID:19483382
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:40,226,368...40,257,617
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Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Omeprazole affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:65,630,432...65,636,624
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Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Omeprazole affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
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Cpq
carboxypeptidase Q
affects expression
EXP
Omeprazole affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
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Crem
cAMP responsive element modulator
affects expression
EXP
Omeprazole affects the expression of CREM mRNA
CTD
PMID:19483382
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
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Csnk2b
casein kinase 2 beta
affects expression
EXP
Omeprazole affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
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Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Omeprazole affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
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Ctnna1
catenin alpha 1
affects expression
EXP
Omeprazole affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
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Ctsb
cathepsin B
decreases activity
ISO
Omeprazole results in decreased activity of CTSB protein
CTD
PMID:34871754
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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Ctsd
cathepsin D
multiple interactions
EXP
Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein]
CTD
PMID:20165931
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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Ctse
cathepsin E
decreases expression
EXP
Omeprazole results in decreased expression of CTSE
CTD
PMID:7575556
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:45,644,147...45,666,722
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression multiple interactions
ISO
Omeprazole results in decreased expression of CXCR4 mRNA AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]
CTD
PMID:25826687
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression increases activity decreases activity
ISO EXP
AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter] Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA] Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein Omeprazole results in increased activity of CYP1A1 protein [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA] Omeprazole results in decreased activity of CYP1A1 protein Omeprazole results in increased activity of CYP1A1 promoter
CTD
PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 PMID:9395520 PMID:9860486 PMID:10103034 PMID:10859152 PMID:11454723 PMID:11849738 PMID:12040753 PMID:12623754 PMID:12841937 PMID:14742684 PMID:14987951 PMID:15681896 PMID:15860653 PMID:17202759 PMID:17954527 PMID:18420780 PMID:18502397 PMID:19118567 PMID:20171196 PMID:21666223 PMID:21703235 PMID:21784029 PMID:22687989 PMID:25626140 PMID:25826687 PMID:26187180 PMID:26272953 More...
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity multiple interactions increases expression increases activity
ISO EXP
Omeprazole results in decreased activity of CYP1A2 protein [Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein
CTD
PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 PMID:15681896 PMID:15802389 PMID:16035375 PMID:17954527 PMID:18332078 PMID:18420780 PMID:18502397 PMID:19118567 PMID:19230594 PMID:20171196 PMID:21784029 PMID:21924250 PMID:22524704 PMID:22687989 PMID:23274770 PMID:23850985 PMID:24752503 PMID:25626140 PMID:26204831 PMID:27794450 PMID:30044681 PMID:31863871 PMID:36288780 More...
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions affects expression increases expression decreases activity
ISO
Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] Omeprazole affects the expression of CYP1B1 mRNA Omeprazole results in increased expression of CYP1B1 mRNA Omeprazole results in decreased activity of CYP1B1 protein
CTD
PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression
EXP
Omeprazole affects the expression of CYP2A1 mRNA
CTD
PMID:19483382
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
Omeprazole results in increased expression of CYP2B1 mRNA; Omeprazole results in increased expression of CYP2B1 protein
CTD
PMID:9152597 PMID:19118567
NCBI chr 1:90,646,098...90,669,762
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression increases expression
EXP
Omeprazole affects the expression of CYP2B2 mRNA Omeprazole results in increased expression of CYP2B2 protein
CTD
PMID:9152597 PMID:19483382
NCBI chr 1:90,722,243...90,736,272
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression decreases activity increases expression increases activity
EXP ISO
Omeprazole affects the expression of CYP2B3 mRNA Omeprazole results in decreased activity of CYP2B10 protein Omeprazole results in increased expression of CYP2B6 mRNA Omeprazole results in increased activity of CYP2B6 protein
CTD
PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704
NCBI chr 1:90,780,468...90,859,852
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
affects metabolic processing decreases activity multiple interactions increases metabolic processing decreases metabolic processing increases hydroxylation
ISO
CYP2C19 protein affects the metabolism of Omeprazole Omeprazole results in decreased activity of CYP2C19 protein [5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel] CYP2C19 protein results in increased metabolism of Omeprazole CYP2C19 gene alternative form results in decreased metabolism of Omeprazole CYP2C19 protein results in increased hydroxylation of Omeprazole
CTD
PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 PMID:12485723 PMID:12637241 PMID:14586384 PMID:15258107 PMID:15286053 PMID:15306208 PMID:15626586 PMID:16035375 PMID:17565714 PMID:17702393 PMID:18511451 PMID:18520598 PMID:19812348 PMID:20573087 PMID:21277363 PMID:21795468 PMID:21915887 PMID:22634058 PMID:26599973 PMID:31515991 More...
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
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Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
increases expression
EXP
Omeprazole results in increased expression of CYP2D9 mRNA
CTD
PMID:19118567
NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479
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Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Omeprazole affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:115,797,789...115,802,158
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression decreases activity
EXP ISO
Omeprazole affects the expression of CYP2D4 mRNA Omeprazole results in decreased activity of CYP2D6 protein
CTD
PMID:18420780 PMID:19483382
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein
CTD
PMID:15802389 PMID:36243147
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Omeprazole affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
EXP
Omeprazole affects the expression of CYP2J4 mRNA
CTD
PMID:19483382
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
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Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Omeprazole affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:91,574,572...91,579,215
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions increases expression increases metabolic processing affects metabolic processing
ISO
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]; Omeprazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Omeprazole results in increased expression of and results in increased activity of CYP3A4 protein Omeprazole results in increased expression of CYP3A4 mRNA; Omeprazole results in increased expression of CYP3A4 protein CYP3A4 protein results in increased metabolism of Omeprazole CYP3A4 protein affects the metabolism of Omeprazole
CTD
PMID:7870052 PMID:8930576 PMID:9744552 PMID:12235278 PMID:12485723 PMID:12695340 PMID:15286053 PMID:15466163 PMID:15626586 PMID:15802389 PMID:17041008 PMID:17565714 PMID:17954527 PMID:19118567 PMID:19299527 PMID:22634058 More...
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression increases expression
EXP
Omeprazole affects the expression of CYP3A23-3A1 mRNA Omeprazole results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:19118567 PMID:19483382
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression increases expression
EXP ISO
Omeprazole affects the expression of CYP3A9 mRNA Omeprazole results in increased expression of CYP3A5 mRNA
CTD
PMID:19118567 PMID:19483382
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
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Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Omeprazole affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:133,938,883...133,970,226
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Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Omeprazole affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
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Dbi
diazepam binding inhibitor
affects expression
EXP
Omeprazole affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
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Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Omeprazole affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672
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Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Omeprazole affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,504,730...106,506,619
G
Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Omeprazole results in increased expression of DDIT3 protein
CTD
PMID:27358234
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Omeprazole affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
G
Dexi
Dexi homolog
affects expression
EXP
Omeprazole affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648
G
Dgat1
diacylglycerol O-acyltransferase 1
affects expression
EXP
Omeprazole affects the expression of DGAT1 mRNA
CTD
PMID:19483382
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
G
Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Omeprazole affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
G
Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Omeprazole affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:32,936,522...32,948,101
G
Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Omeprazole affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:45,504,344...45,537,094
Ensembl chr10:46,003,845...46,036,499
G
Dhx16
DEAH-box helicase 16
affects expression
EXP
Omeprazole affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
G
Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Omeprazole affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
G
Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression
EXP
Omeprazole affects the expression of DNAJC3 mRNA
CTD
PMID:19483382
NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
G
Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Omeprazole affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Omeprazole affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Omeprazole affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:176,597,986...176,625,848
G
Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Omeprazole affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
G
Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Omeprazole affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
G
Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Omeprazole affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
G
Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Omeprazole affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
G
Egf
epidermal growth factor
multiple interactions
ISO
Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein]
CTD
PMID:18431645
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
EXP
Omeprazole affects the expression of EHHADH mRNA
CTD
PMID:19483382
NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
G
Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Omeprazole affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
affects expression
EXP
Omeprazole affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
G
Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Omeprazole affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:27,719,321...27,736,346
G
Enc1
ectodermal-neural cortex 1
affects expression
EXP
Omeprazole affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
G
Eno1
enolase 1
affects expression
EXP
Omeprazole affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
G
Enpep
glutamyl aminopeptidase
affects expression
EXP
Omeprazole affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
G
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Omeprazole affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
G
Ep300
E1A binding protein p300
multiple interactions
ISO
Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]
CTD
PMID:21703235
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
G
Epcam
epithelial cell adhesion molecule
affects expression
EXP
Omeprazole affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
G
Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Omeprazole affects the expression of ERP29 mRNA
CTD
PMID:19483382
NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
G
Esd
esterase D
affects expression
EXP
Omeprazole affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
G
Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Omeprazole affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:102,988,499...103,002,659
G
Faah
fatty acid amide hydrolase
affects expression
EXP
Omeprazole affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
G
Fads2
fatty acid desaturase 2
affects expression
EXP
Omeprazole affects the expression of FADS2 mRNA
CTD
PMID:19483382
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
G
Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Omeprazole affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression
EXP
Omeprazole affects the expression of FDFT1 mRNA
CTD
PMID:19483382
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
G
Fdps
farnesyl diphosphate synthase
affects expression
EXP
Omeprazole affects the expression of FDPS mRNA
CTD
PMID:19483382
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
G
Fdx2
ferredoxin 2
affects expression
EXP
Omeprazole affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Omeprazole affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
G
Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Omeprazole affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:10,098,571...10,102,083
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Omeprazole affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
G
Gast
gastrin
increases expression
ISO EXP
Omeprazole results in increased expression of GAST protein
CTD
PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 PMID:17652263 More...
NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
G
Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Omeprazole affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
G
Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Omeprazole affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
G
Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Omeprazole affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:38,326,594...38,349,647
G
Ggt1
gamma-glutamyltransferase 1
multiple interactions
EXP
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA
CTD
PMID:22687989
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
G
Gjb1
gap junction protein, beta 1
affects expression
EXP
Omeprazole affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Omeprazole affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,512,660...40,554,975
G
Gpx1
glutathione peroxidase 1
affects expression
EXP
Omeprazole affects the expression of GPX1 mRNA
CTD
PMID:19483382
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx2
glutathione peroxidase 2
multiple interactions
EXP
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA
CTD
PMID:22687989
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
G
Gpx4
glutathione peroxidase 4
affects expression
EXP
Omeprazole affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Omeprazole affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
G
Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Omeprazole affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:78,517,052...78,522,861
G
Gsta5
glutathione S-transferase alpha 5
multiple interactions increases expression
EXP
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA Omeprazole results in increased expression of GSTA5 mRNA
CTD
PMID:17202759 PMID:22687989
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
G
Gstp1
glutathione S-transferase pi 1
increases expression
EXP
Omeprazole results in increased expression of GSTP1 mRNA
CTD
PMID:19118567
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Omeprazole affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
G
Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Omeprazole affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
G
Gulo
gulonolactone (L-) oxidase
affects expression
EXP
Omeprazole affects the expression of GULO mRNA
CTD
PMID:19483382
NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422
G
Gzma
granzyme A
affects expression
EXP
Omeprazole affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
G
H3f3b
H3.3 histone B
affects expression
EXP
Omeprazole affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
G
Hal
histidine ammonia lyase
affects expression
EXP
Omeprazole affects the expression of HAL mRNA
CTD
PMID:19483382
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
G
Hamp
hepcidin antimicrobial peptide
increases secretion multiple interactions increases expression
ISO
Omeprazole results in increased secretion of HAMP protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA] Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein
CTD
PMID:31669099
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Omeprazole affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
G
Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Omeprazole affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
G
Hbb
hemoglobin subunit beta
affects expression
EXP
Omeprazole affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
G
Hdc
histidine decarboxylase
affects expression increases expression increases stability multiple interactions
EXP
Omeprazole affects the expression of HDC mRNA Omeprazole results in increased expression of HDC mRNA Omeprazole results in increased stability of HDC protein Omeprazole results in increased expression of and results in increased activity of HDC protein
CTD
PMID:12763636 PMID:19483382
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Omeprazole affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
G
Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Omeprazole affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein
CTD
PMID:16712795 PMID:27725188
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Omeprazole affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Omeprazole affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:106,417,902...106,452,859
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Omeprazole affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:45,515,373...45,604,467
G
Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Omeprazole affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions decreases expression
EXP
Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein] Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein
CTD
PMID:15223672 PMID:16945336
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
G
Hspa1l
heat shock protein family A (Hsp70) member 1 like
multiple interactions
EXP
Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA]
CTD
PMID:25637687
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
G
Htra1
HtrA serine peptidase 1
affects expression
EXP
Omeprazole affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
G
Ier3
immediate early response 3
multiple interactions
ISO
[Omeprazole co-treated with CCKBR protein] results in increased expression of IER3
CTD
PMID:17704804
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
G
Ifng
interferon gamma
multiple interactions
ISO
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
CTD
PMID:19232345
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Igf1
insulin-like growth factor 1
affects expression
EXP
Omeprazole affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
G
Igfals
insulin-like growth factor binding protein, acid labile subunit
affects expression
EXP
Omeprazole affects the expression of IGFALS mRNA
CTD
PMID:19483382
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Omeprazole affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
G
Il10
interleukin 10
multiple interactions
ISO EXP
Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein]
CTD
PMID:26970604 PMID:38341112
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
G
Il16
interleukin 16
multiple interactions
EXP
Omeprazole inhibits the reaction [Ethanol results in increased expression of IL16 protein]
CTD
PMID:38341112
NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023
G
Il1b
interleukin 1 beta
multiple interactions
EXP
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein]
CTD
PMID:32418911
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
multiple interactions
EXP ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein] Omeprazole inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD
PMID:25637687 PMID:32418911 PMID:38341112
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Impa1
inositol monophosphatase 1
affects expression
EXP
Omeprazole affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:93,370,299...93,391,468
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Omeprazole affects the expression of INHBE mRNA
CTD
PMID:19483382
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
G
Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Omeprazole affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,873,121...18,875,955
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Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Omeprazole affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
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Jak1
Janus kinase 1
affects expression
EXP
Omeprazole affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
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Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Omeprazole affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:16,252,424...16,270,719
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Kdr
kinase insert domain receptor
affects expression multiple interactions
EXP ISO
Omeprazole affects the expression of KDR mRNA Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]
CTD
PMID:19483382 PMID:26272953
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
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Krt8
keratin 8
affects expression
EXP
Omeprazole affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
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Lcat
lecithin cholesterol acyltransferase
affects expression
EXP
Omeprazole affects the expression of LCAT mRNA
CTD
PMID:19483382
NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
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Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Omeprazole affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516
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Lipc
lipase C, hepatic type
affects expression
EXP
Omeprazole affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
G
Lox
lysyl oxidase
affects expression
EXP
Omeprazole affects the expression of LOX mRNA
CTD
PMID:19483382
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
G
Lrp3
LDL receptor related protein 3
affects expression
EXP
Omeprazole affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:96,981,815...96,996,057
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Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Omeprazole affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246
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Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Omeprazole affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
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Mapk14
mitogen activated protein kinase 14
multiple interactions
ISO
Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]
CTD
PMID:17406807
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
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Masp2
MBL associated serine protease 2
affects expression
EXP
Omeprazole affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705
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Me1
malic enzyme 1
affects expression multiple interactions
EXP
Omeprazole affects the expression of ME1 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
G
Mmp14
matrix metallopeptidase 14
multiple interactions
EXP
Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein]
CTD
PMID:16934674
NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
G
Mmp2
matrix metallopeptidase 2
multiple interactions
EXP
Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein]
CTD
PMID:16934674
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
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Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Omeprazole affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
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Mpo
myeloperoxidase
multiple interactions decreases activity
ISO EXP
Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein] Omeprazole results in decreased activity of MPO protein Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein]
CTD
PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 PMID:29770154 PMID:31095933 PMID:33245926 More...
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Mro
maestro
affects expression
EXP
Omeprazole affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:69,725,798...69,743,031
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Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Omeprazole affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:21,830,834...21,834,607
Ensembl chr 9:21,830,835...21,834,641
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Mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Omeprazole affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777
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Mug2
murinoglobulin 2
affects expression
EXP
Omeprazole affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:155,164,061...155,236,894
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Myadm
myeloid-associated differentiation marker
affects expression
EXP
Omeprazole affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:74,775,698...74,789,710
G
Mycbp2
MYC binding protein 2
affects expression
EXP
Omeprazole affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
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Myo1d
myosin ID
affects expression
EXP
Omeprazole affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,975,122...66,263,958
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Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Omeprazole affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715
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Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Omeprazole affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
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Nat8
N-acetyltransferase 8
affects expression
EXP
Omeprazole affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
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Ncoa1
nuclear receptor coactivator 1
multiple interactions
ISO
Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
CTD
PMID:21703235
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
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Ndrg2
NDRG family member 2
affects expression
EXP
Omeprazole affects the expression of NDRG2 mRNA
CTD
PMID:19483382
NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
G
Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Omeprazole affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909 Ensembl chr 5:184,849,197...185,028,909 Ensembl chr14:184,849,197...185,028,909
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Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Omeprazole affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
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Neu2
neuraminidase 2
affects expression
EXP
Omeprazole affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:95,696,507...95,715,208
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]
CTD
PMID:27725188
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
EXP
Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein]
CTD
PMID:32418911
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
G
Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Omeprazole affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
G
Nipal2
NIPA-like domain containing 2
affects expression
EXP
Omeprazole affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:67,659,628...67,769,959
G
Nit1
nitrilase 1
affects expression
EXP
Omeprazole affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
G
Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
EXP
Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]
CTD
PMID:32418911
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Omeprazole affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:78,898,097...78,903,514
Ensembl chr20:11,179,066...11,179,497 Ensembl chr10:11,179,066...11,179,497
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
EXP ISO
Omeprazole results in increased expression of NQO1 mRNA Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein] [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA
CTD
PMID:17202759 PMID:22687989 PMID:26272953
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions increases activity
ISO EXP
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]
CTD
PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression decreases metabolic processing increases expression
EXP ISO
Omeprazole affects the expression of NR1I3 mRNA NR1I3 gene mutant form results in decreased metabolism of Omeprazole Omeprazole results in increased expression of NR1I3 mRNA
CTD
PMID:19118567 PMID:19483382 PMID:27434302
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Omeprazole affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
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Oaf
out at first homolog
affects expression
EXP
Omeprazole affects the expression of OAF mRNA
CTD
PMID:19483382
NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
G
Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Omeprazole affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
G
Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Omeprazole affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
G
Olr59
olfactory receptor 59
affects expression
EXP
Omeprazole affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:166,604,141...166,623,265
G
Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Omeprazole affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:221,874,948...221,940,267
G
Otc
ornithine transcarbamylase
affects expression
EXP
Omeprazole affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555
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Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Omeprazole affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Omeprazole affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
G
Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
Omeprazole results in increased cleavage of PARP1 protein
CTD
PMID:15461867
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
G
Pc
pyruvate carboxylase
affects expression
EXP
Omeprazole affects the expression of PCX mRNA
CTD
PMID:19483382
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:211,228,731...211,329,940
G
Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Omeprazole affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:110,469,934...110,520,187
G
Pcna
proliferating cell nuclear antigen
multiple interactions
EXP ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein] Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]
CTD
PMID:19251492 PMID:26970604
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Omeprazole affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:128,839,232...129,052,128
G
Pctp
phosphatidylcholine transfer protein
affects expression
EXP
Omeprazole affects the expression of PCTP mRNA
CTD
PMID:19483382
NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
G
Pdcl3
phosducin-like 3
affects expression
EXP
Omeprazole affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:48,723,767...48,739,529
G
Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Omeprazole affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:128,841,917...128,867,327
G
Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Omeprazole affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
G
Pex19
peroxisomal biogenesis factor 19
affects expression
EXP
Omeprazole affects the expression of PEX19 mRNA
CTD
PMID:19483382
NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
G
Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Omeprazole affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
G
Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Omeprazole affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
G
Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Omeprazole affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Omeprazole affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082
G
Pklr
pyruvate kinase L/R
affects expression
EXP
Omeprazole affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
G
Pla2g4a
phospholipase A2 group 4A
increases phosphorylation multiple interactions
ISO
Omeprazole results in increased phosphorylation of PLA2G4A protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]
CTD
PMID:25797602
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
G
Plbd1
phospholipase B domain containing 1
affects expression
EXP
Omeprazole affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:171,204,198...171,260,488
G
Plg
plasminogen
affects expression
EXP
Omeprazole affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
G
Pls3
plastin 3
affects expression
EXP
Omeprazole affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
G
Pon2
paraoxonase 2
affects expression
EXP
Omeprazole affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996
G
Pou2f2
POU class 2 homeobox 2
multiple interactions
ISO EXP
Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein]
CTD
PMID:30452898
NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Omeprazole affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:188,676,965...188,678,599
G
Prdx2
peroxiredoxin 2
affects expression
EXP
Omeprazole affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
G
Prdx6
peroxiredoxin 6
affects expression
EXP
Omeprazole affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
G
Prl
prolactin
increases expression
ISO
Omeprazole results in increased expression of PRL protein
CTD
PMID:20726208
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
G
Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Omeprazole affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
G
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Omeprazole affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Omeprazole affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:78,500,736...78,531,717
G
Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Omeprazole affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Omeprazole affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
G
Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Omeprazole affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:125,122,490...125,134,858
G
Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Omeprazole affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:97,487,632...97,499,176
G
Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Omeprazole affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Omeprazole affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Omeprazole affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP ISO
[Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]
CTD
PMID:23038005 PMID:26970604
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Ptms
parathymosin
affects expression
EXP
Omeprazole affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Omeprazole affects the expression of PTPRF mRNA
CTD
PMID:19483382
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
G
Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Omeprazole affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909
G
Pygl
glycogen phosphorylase L
affects expression
EXP
Omeprazole affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
G
Rab5if
RAB5 interacting factor
affects expression
EXP
Omeprazole affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
EXP ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]
CTD
PMID:19251492 PMID:30452898 PMID:32418911
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Retsat
retinol saturase
increases expression
EXP
Omeprazole results in increased expression of RETSAT mRNA
CTD
PMID:25626140
NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:106,211,436...106,229,552
G
Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Omeprazole affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692
G
Rnase4
ribonuclease A family member 4
affects expression
EXP
Omeprazole affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
G
Rnf103
ring finger protein 103
affects expression
EXP
Omeprazole affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:105,084,686...105,106,809
G
Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Omeprazole affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
G
Rpl11
ribosomal protein L11
affects expression
EXP
Omeprazole affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
G
Rpl13
ribosomal protein L13
affects expression
EXP
Omeprazole affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
G
Rpl15
ribosomal protein L15
affects expression
EXP
Omeprazole affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
G
Rpl17
ribosomal protein L17
affects expression
EXP
Omeprazole affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638 Ensembl chr18:111,722,010...111,722,638
G
Rpl23
ribosomal protein L23
affects expression
EXP
Omeprazole affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
G
Rpl3
ribosomal protein L3
affects expression
EXP
Omeprazole affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
G
Rpl32
ribosomal protein L32
affects expression
EXP
Omeprazole affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:150,536,646...150,540,214
G
Rpl4
ribosomal protein L4
affects expression
EXP
Omeprazole affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
G
Rpn2
ribophorin II
affects expression
EXP
Omeprazole affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:166,361,955...166,409,272
Ensembl chr 3:166,362,049...166,409,922
G
Rps14
ribosomal protein S14
affects expression
EXP
Omeprazole affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
G
Rps18
ribosomal protein S18
affects expression
EXP
Omeprazole affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423
G
Rps19
ribosomal protein S19
affects expression
EXP
Omeprazole affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132 Ensembl chr 1:104,324,520...104,325,132
G
Rps20
ribosomal protein S20
affects expression
EXP
Omeprazole affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621 Ensembl chr 9:42,839,965...43,095,621 Ensembl chr 5:42,839,965...43,095,621
G
Rps3a
ribosomal protein S3a
affects expression
EXP
Omeprazole affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
G
Rps6
ribosomal protein S6
affects expression
EXP
Omeprazole affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
G
Rps8
ribosomal protein S8
affects expression
EXP
Omeprazole affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
G
Rras2
RAS related 2
affects expression
EXP
Omeprazole affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
G
RT1-DMa
RT1 class II, locus DMa
affects expression
ISO
Omeprazole affects the expression of HLA-DMA mRNA
CTD
PMID:25811541
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,708,933...4,712,335
G
RT1-M3-1
RT1 class Ib, locus M3, gene 1
affects expression
ISO
Omeprazole affects the expression of HLA-G mRNA
CTD
PMID:25811541
NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366
G
RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Omeprazole affects the expression of RT1-S3 mRNA
CTD
PMID:19483382
NCBI chr20:2,675,463...2,680,229
G
S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Omeprazole affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
G
Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Omeprazole affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:8,185,985...8,218,898
G
Sdc2
syndecan 2
affects expression
EXP
Omeprazole affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294
G
Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Omeprazole affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044
G
Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Omeprazole affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:59,841,090...59,850,641
Ensembl chr 8:59,841,090...59,850,641
G
Sell
selectin L
decreases expression
EXP
Omeprazole results in decreased expression of SELL protein
CTD
PMID:17652263
NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
G
Serinc3
serine incorporator 3
affects expression
EXP
Omeprazole affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
G
Serpina1
serpin family A member 1
affects expression
EXP
Omeprazole affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
G
Serpina10
serpin family A member 10
affects expression
EXP
Omeprazole affects the expression of SERPINA10 mRNA
CTD
PMID:19483382
NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332
G
Serpina4
serpin family A member 4
affects expression
EXP
Omeprazole affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
G
Serpinf2
serpin family F member 2
affects expression
EXP
Omeprazole affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
G
Serping1
serpin family G member 1
decreases expression
EXP
Omeprazole results in decreased expression of SERPING1 mRNA
CTD
PMID:25626140
NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
G
Sfxn1
sideroflexin 1
affects expression
EXP
Omeprazole affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
G
Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Omeprazole affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Omeprazole affects the expression of SLC22A1 mRNA
CTD
PMID:19483382
NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
G
Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
G
Slc22a5
solute carrier family 22 member 5
multiple interactions
EXP
Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]
CTD
PMID:19041296
NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077
G
Slc22a8
solute carrier family 22 member 8
multiple interactions
ISO
[Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican
CTD
PMID:36243147
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
G
Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Omeprazole affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702
G
Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Omeprazole affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:35,145,721...35,328,360
G
Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Omeprazole affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:27,499,165...27,506,309
G
Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Omeprazole affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
G
Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Omeprazole affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:226,929,644...226,992,667
G
Slc40a1
solute carrier family 40 member 1
decreases expression
ISO
Omeprazole results in decreased expression of SLC40A1 protein
CTD
PMID:31669099
NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
G
Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Omeprazole affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
G
Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Omeprazole affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:73,702,472...73,739,678
Ensembl chr18:75,977,458...76,014,651
G
Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Omeprazole affects the expression of SLC6A6 mRNA
CTD
PMID:19483382
NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
G
Slco1a1
solute carrier organic anion transporter family, member 1a1
affects expression
EXP
Omeprazole affects the expression of SLCO1A1 mRNA
CTD
PMID:19483382
NCBI chr 4:174,877,045...174,950,900
Ensembl chr 4:176,607,687...176,681,992
G
Slco1a4
solute carrier organic anion transporter family, member 1a4
increases expression
ISO
Omeprazole results in increased expression of SLCO1A2 mRNA
CTD
PMID:19118567
NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
G
Sod1
superoxide dismutase 1
multiple interactions
ISO
Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein]
CTD
PMID:28849987
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Omeprazole affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:134,605,750...134,646,752
G
Srm
spermidine synthase
affects expression
EXP
Omeprazole affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
G
Srprb
SRP receptor subunit beta
affects expression
EXP
Omeprazole affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:112,647,577...112,661,524
G
Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Omeprazole affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
G
St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Omeprazole affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:55,530,248...55,598,720
G
St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Omeprazole affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
G
Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression
EXP
Omeprazole affects the expression of SUCLG1 mRNA
CTD
PMID:19483382
NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:106,866,114...106,895,689
G
Surf4
surfeit 4
affects expression
EXP
Omeprazole affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:30,646,435...30,659,641
Ensembl chr 3:30,638,299...30,661,390
G
Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Omeprazole affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:106,920,970...106,966,543
G
Tacr1
tachykinin receptor 1
multiple interactions
ISO
Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein]
CTD
PMID:16091555
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:116,478,617...116,647,492
G
Tgfb1
transforming growth factor, beta 1
increases expression
ISO
Omeprazole results in increased expression of TGFB1 protein
CTD
PMID:36243147
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
G
Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Omeprazole affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
G
Thnsl2
threonine synthase-like 2
affects expression
EXP
Omeprazole affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:104,670,925...104,691,959
G
Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Omeprazole affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:78,314,900...78,319,362
Ensembl chr18:80,589,783...80,594,237
G
Timp2
TIMP metallopeptidase inhibitor 2
multiple interactions
EXP
Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein]
CTD
PMID:16934674
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
G
Tkfc
triokinase and FMN cyclase
affects expression
EXP
Omeprazole affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
G
Tlr4
toll-like receptor 4
multiple interactions
EXP
Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]
CTD
PMID:32418911
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
G
Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Omeprazole affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657
G
Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
EXP
Omeprazole affects the expression of TEGT mRNA
CTD
PMID:19483382
NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
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Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Omeprazole affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
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Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Omeprazole affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606
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Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Omeprazole affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:41,505,167...41,512,243
Ensembl chr18:41,478,539...41,512,243
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Tmem123
transmembrane protein 123
affects expression
EXP
Omeprazole affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
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Tmem97
transmembrane protein 97
affects expression
EXP
Omeprazole affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818
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Tnf
tumor necrosis factor
multiple interactions
ISO EXP
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein] Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD
PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 PMID:38341112 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Txn1
thioredoxin 1
affects expression
EXP
Omeprazole affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
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Txnl1
thioredoxin-like 1
affects expression
EXP
Omeprazole affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
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Tyr
tyrosinase
multiple interactions decreases expression
ISO
Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] Omeprazole results in decreased expression of TYR protein
CTD
PMID:25337692
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Omeprazole affects the expression of UBA52 mRNA
CTD
PMID:19483382
NCBI chr16:18,952,583...18,954,780
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Omeprazole affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:32,041,190...32,071,252
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Omeprazole affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases expression affects expression
ISO EXP
Omeprazole results in increased expression of UGT1A1 mRNA Omeprazole affects the expression of UGT1A1 mRNA
CTD
PMID:19118567 PMID:19483382 PMID:25626140
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
increases expression
ISO
Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA
CTD
PMID:19118567
NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a3
UDP glycosyltransferase 1 family, polypeptide A3
increases expression
ISO
Omeprazole results in increased expression of UGT1A5 mRNA
CTD
PMID:19118567
NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a5
UDP glucuronosyltransferase family 1 member A5
increases expression
ISO
Omeprazole results in increased expression of UGT1A4 mRNA
CTD
PMID:19118567
NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
multiple interactions increases expression
EXP ISO
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA Omeprazole results in increased expression of UGT1A6 mRNA
CTD
PMID:19118567 PMID:22687989
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases expression
ISO
Omeprazole results in increased expression of UGT1A9 mRNA
CTD
PMID:19118567
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
increases expression
EXP
Omeprazole results in increased expression of UGT2B1 mRNA
CTD
PMID:25626140
NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
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Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Omeprazole affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,955,764...9,959,047
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Vnn1
vanin 1
affects expression
EXP
Omeprazole affects the expression of VNN1 mRNA
CTD
PMID:19483382
NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
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Wdr26
WD repeat domain 26
affects expression
EXP
Omeprazole affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:95,462,020...95,503,738
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Omeprazole affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Omeprazole affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:70,225,045...70,240,102
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Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Omeprazole affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein
CTD
PMID:10103034
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression
ISO
Mycophenolic Acid promotes the reaction [Esomeprazole results in increased expression of CYP1A1 mRNA]
CTD
PMID:25929522
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Abca1
ATP binding cassette subfamily A member 1
increases expression
ISO
Omeprazole results in increased expression of ABCA1 mRNA
CTD
PMID:20060385
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity
ISO
Omeprazole results in decreased activity of ABCB11 protein
CTD
PMID:20829430
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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Abcb1a
ATP binding cassette subfamily B member 1A
affects expression multiple interactions
EXP ISO
Omeprazole affects the expression of ABCB1A mRNA Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein] Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
CTD
PMID:19483382 PMID:30452898
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abcb4
ATP binding cassette subfamily B member 4
decreases expression
ISO
Omeprazole results in decreased expression of ABCB4 mRNA
CTD
PMID:12040753
NCBI chr 4:26,106,895...26,164,440
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Abcc2
ATP binding cassette subfamily C member 2
multiple interactions
ISO
[Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein
CTD
PMID:35447140
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
Omeprazole results in increased expression of ABCC3 mRNA
CTD
PMID:19118567
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Omeprazole affects the expression of ABCC6 mRNA
CTD
PMID:19483382
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
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Abcg2
ATP binding cassette subfamily G member 2
increases expression multiple interactions
ISO
Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]
CTD
PMID:20804740 PMID:31348918
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
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Abcg5
ATP binding cassette subfamily G member 5
affects expression
EXP
Omeprazole affects the expression of ABCG5 mRNA
CTD
PMID:19483382
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
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Abhd1
abhydrolase domain containing 1
affects expression
EXP
Omeprazole affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:31,142,476...31,147,464
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Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Omeprazole affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Omeprazole affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,775,016...9,781,447
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Acaca
acetyl-CoA carboxylase alpha
affects expression
EXP
Omeprazole affects the expression of ACACA mRNA
CTD
PMID:19483382
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
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Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Omeprazole affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:75,783,689...75,822,164
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Ace2
angiotensin converting enzyme 2
decreases expression
EXP ISO
Omeprazole results in decreased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
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Aco1
aconitase 1
affects expression
EXP
Omeprazole affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:60,055,866...60,112,600
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Aco2
aconitase 2
affects expression
EXP
Omeprazole affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:115,265,791...115,308,892
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Acot12
acyl-CoA thioesterase 12
affects expression
EXP
Omeprazole affects the expression of ACOT12 mRNA
CTD
PMID:19483382
NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298
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Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Omeprazole affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
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Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Omeprazole affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
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Add1
adducin 1
affects expression
EXP
Omeprazole affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
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Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
decreases expression
ISO
Omeprazole results in decreased expression of ADH1C mRNA
CTD
PMID:12040753
NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Omeprazole affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
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Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Omeprazole affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:23,135,809...23,216,622
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Afm
afamin
affects expression
EXP
Omeprazole affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
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Agt
angiotensinogen
affects expression
EXP
Omeprazole affects the expression of AGT mRNA
CTD
PMID:19483382
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Omeprazole affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
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Ahr
aryl hydrocarbon receptor
multiple interactions increases response to substance affects localization decreases expression increases expression increases activity decreases activity
ISO EXP
AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein] [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein] AHR protein results in increased susceptibility to Omeprazole Omeprazole affects the localization of AHR protein Omeprazole results in decreased activity of AHR protein
CTD
PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 PMID:21703235 PMID:21861773 PMID:21924250 PMID:22687989 PMID:23850985 PMID:25797602 PMID:25826687 PMID:26187274 PMID:26272953 PMID:31669099 More...
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Omeprazole affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
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Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Omeprazole affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
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Akr7a3
aldo-keto reductase family 7 member A3
affects expression multiple interactions
EXP
Omeprazole affects the expression of AKR7A3 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression multiple interactions
EXP
Omeprazole affects the expression of ALDH1A1 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
Omeprazole results in increased expression of ALDH1A3 mRNA
CTD
PMID:12040753
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
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Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
affects expression
EXP
Omeprazole affects the expression of ALDH1A7 mRNA
CTD
PMID:19483382
NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:227,627,448...227,672,523
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Omeprazole affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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Aldh3a1
aldehyde dehydrogenase 3 family, member A1
increases expression
ISO
Omeprazole results in increased expression of ALDH3A1 mRNA
CTD
PMID:12040753
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
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Alkbh7
alkB homolog 7
affects expression
EXP
Omeprazole affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
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Ankrd40
ankyrin repeat domain 40
increases expression
EXP
Omeprazole results in increased expression of TMPRSS2 mRNA
CTD
PMID:32808185
NCBI chr10:79,778,966...79,792,212
Ensembl chr10:56,415,260...56,416,345 Ensembl chr10:56,415,260...56,416,345
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Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Omeprazole affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
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Apcs
amyloid P component, serum
affects expression
EXP
Omeprazole affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
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Apoa4
apolipoprotein A4
affects expression
EXP
Omeprazole affects the expression of APOA4 mRNA
CTD
PMID:19483382
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
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Apoh
apolipoprotein H
affects expression
EXP
Omeprazole affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
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Apool
apolipoprotein O-like
affects expression
EXP
Omeprazole affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:81,569,960...81,635,906
Ensembl chr X:81,570,053...81,640,036
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Arg1
arginase 1
affects expression
EXP
Omeprazole affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
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Arl6ip1
ARL6 interacting reticulophagy regulator 1
affects expression
EXP
Omeprazole affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
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Arnt
aryl hydrocarbon receptor nuclear translocator
multiple interactions affects localization
ISO EXP
Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter] Omeprazole affects the localization of [ARNT protein co-treated with AHR protein] Omeprazole affects the localization of ARNT protein
CTD
PMID:9395520 PMID:21703235 PMID:25826687
NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
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Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Omeprazole affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
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Atf5
activating transcription factor 5
affects expression
EXP
Omeprazole affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
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Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Omeprazole affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
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Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Omeprazole affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
G
Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Omeprazole affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Omeprazole affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:59,033,020...59,035,980
G
Atp7a
ATPase copper transporting alpha
multiple interactions
ISO
Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
CTD
PMID:25337692
NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093
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Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Omeprazole affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein]
CTD
PMID:30452898
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]
CTD
PMID:30452898
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
G
Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Omeprazole affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
G
Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Omeprazole affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083
G
Bmf
Bcl2 modifying factor
affects expression
EXP
Omeprazole affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
G
Bmx
BMX non-receptor tyrosine kinase
multiple interactions
ISO
BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]
CTD
PMID:21861773
NCBI chr X:30,227,251...30,290,015
Ensembl chr X:33,859,129...33,921,874
G
Bnip3
BCL2 interacting protein 3
affects expression
EXP
Omeprazole affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
G
Btf3
basic transcription factor 3
affects expression
EXP
Omeprazole affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125 Ensembl chr13:31,394,011...31,401,125
G
C1qa
complement C1q A chain
decreases expression
EXP
Omeprazole results in decreased expression of C1QA mRNA
CTD
PMID:25626140
NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
G
C1qbp
complement C1q binding protein
affects expression
EXP
Omeprazole affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
G
C1qc
complement C1q C chain
decreases expression
EXP
Omeprazole results in decreased expression of C1QC mRNA
CTD
PMID:25626140
NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
G
C1s
complement C1s
affects expression
EXP
Omeprazole affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
G
C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Omeprazole affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:50,694,563...50,759,016
G
C4bpa
complement component 4 binding protein, alpha
affects expression decreases expression
EXP
Omeprazole affects the expression of C4BPA mRNA Omeprazole results in decreased expression of C4BPA mRNA
CTD
PMID:19483382 PMID:25626140
NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
G
C4bpb
complement component 4 binding protein, beta
decreases expression
EXP
Omeprazole results in decreased expression of C4BPB mRNA
CTD
PMID:25626140
NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
G
C7
complement C7
affects expression
EXP
Omeprazole affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
G
C8b
complement C8 beta chain
affects expression
EXP
Omeprazole affects the expression of C8B mRNA
CTD
PMID:19483382
NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
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Ca3
carbonic anhydrase 3
affects expression
EXP
Omeprazole affects the expression of CAR3 mRNA
CTD
PMID:19483382
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
G
Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Omeprazole affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
G
Caprin1
cell cycle associated protein 1
affects expression
EXP
Omeprazole affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
G
Car2
carbonic anhydrase 2
affects expression
EXP
Omeprazole affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
G
Casp3
caspase 3
increases activity increases cleavage affects expression multiple interactions
ISO EXP
Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein Omeprazole results in increased cleavage of CASP3 protein Omeprazole affects the expression of CASP3 mRNA Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
CTD
PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 PMID:30452898 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Casp8
caspase 8
increases cleavage
ISO
Omeprazole analog results in increased cleavage of CASP8 protein
CTD
PMID:18336733
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
G
Cat
catalase
increases activity multiple interactions
EXP ISO
Omeprazole results in increased activity of CAT protein Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein] Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD
PMID:18547560 PMID:28849987 PMID:33245926
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
G
Cbr1
carbonyl reductase 1
affects expression
EXP
Omeprazole affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
G
Cckbr
cholecystokinin B receptor
multiple interactions
ISO
[Omeprazole co-treated with CCKBR protein] results in increased expression of IER3
CTD
PMID:17704804
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:169,183,194...169,193,745
G
Ccnd1
cyclin D1
decreases expression
EXP
Omeprazole results in decreased expression of CCND1 mRNA
CTD
PMID:17202759
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Omeprazole results in increased expression of CDKN1A protein
CTD
PMID:27358234
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
G
Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Omeprazole affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
G
Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Omeprazole affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:196,681,681...196,723,812
G
Ces2h
carboxylesterase 2H
affects expression
EXP
Omeprazole affects the expression of CES2 mRNA
CTD
PMID:19483382
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
G
Cfi
complement factor I
affects expression decreases expression
EXP
Omeprazole affects the expression of CFI mRNA Omeprazole results in decreased expression of CFI mRNA
CTD
PMID:19483382 PMID:25626140
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
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Cftr
CF transmembrane conductance regulator
affects metabolic processing
ISO
CFTR protein affects the metabolism of Omeprazole
CTD
PMID:15319328
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
G
Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Omeprazole affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
G
Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Omeprazole affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042
G
Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Omeprazole affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:27,290,868...27,356,939
G
Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Omeprazole affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,918,682...1,924,705
G
Clptm1l
CLPTM1-like
affects expression
EXP
Omeprazole affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077
G
Cmbl
carboxymethylenebutenolidase homolog
affects expression
EXP
Omeprazole affects the expression of CMBL mRNA
CTD
PMID:19483382
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:84,242,512...84,301,880
G
Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Omeprazole affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596
G
Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Omeprazole affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812
G
Cops4
COP9 signalosome subunit 4
affects expression
EXP
Omeprazole affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,382,900...9,413,107
G
Coq3
coenzyme Q3 methyltransferase
affects expression
EXP
Omeprazole affects the expression of COQ3 mRNA
CTD
PMID:19483382
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:40,226,368...40,257,617
G
Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Omeprazole affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:65,630,432...65,636,624
G
Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Omeprazole affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
G
Cpq
carboxypeptidase Q
affects expression
EXP
Omeprazole affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
G
Crem
cAMP responsive element modulator
affects expression
EXP
Omeprazole affects the expression of CREM mRNA
CTD
PMID:19483382
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
G
Csnk2b
casein kinase 2 beta
affects expression
EXP
Omeprazole affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
G
Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Omeprazole affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
G
Ctnna1
catenin alpha 1
affects expression
EXP
Omeprazole affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
G
Ctsb
cathepsin B
decreases activity
ISO
Omeprazole results in decreased activity of CTSB protein
CTD
PMID:34871754
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
G
Ctsd
cathepsin D
multiple interactions
EXP
Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein]
CTD
PMID:20165931
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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Ctse
cathepsin E
decreases expression
EXP
Omeprazole results in decreased expression of CTSE
CTD
PMID:7575556
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:45,644,147...45,666,722
G
Cxcr4
C-X-C motif chemokine receptor 4
decreases expression multiple interactions
ISO
Omeprazole results in decreased expression of CXCR4 mRNA AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]
CTD
PMID:25826687
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases activity multiple interactions increases expression decreases activity
ISO EXP
Omeprazole results in increased activity of CYP1A1 promoter Omeprazole results in increased activity of CYP1A1 protein AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter] Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA] Omeprazole results in decreased activity of CYP1A1 protein Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA]
CTD
PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 PMID:9395520 PMID:9860486 PMID:10103034 PMID:10859152 PMID:11454723 PMID:11849738 PMID:12040753 PMID:12623754 PMID:12841937 PMID:14742684 PMID:14987951 PMID:15681896 PMID:15860653 PMID:17202759 PMID:17954527 PMID:18420780 PMID:18502397 PMID:19118567 PMID:20171196 PMID:21666223 PMID:21703235 PMID:21784029 PMID:22687989 PMID:25626140 PMID:25826687 PMID:26187180 PMID:26272953 More...
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases activity decreases activity multiple interactions increases expression
ISO EXP
Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein Omeprazole results in decreased activity of CYP1A2 protein [Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA
CTD
PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 PMID:15681896 PMID:15802389 PMID:16035375 PMID:17954527 PMID:18332078 PMID:18420780 PMID:18502397 PMID:19118567 PMID:19230594 PMID:20171196 PMID:21784029 PMID:21924250 PMID:22524704 PMID:22687989 PMID:23274770 PMID:23850985 PMID:24752503 PMID:25626140 PMID:26204831 PMID:27794450 PMID:30044681 PMID:31863871 PMID:36288780 More...
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions increases expression decreases activity affects expression
ISO
Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] Omeprazole results in increased expression of CYP1B1 mRNA Omeprazole results in decreased activity of CYP1B1 protein Omeprazole affects the expression of CYP1B1 mRNA
CTD
PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
G
Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression
EXP
Omeprazole affects the expression of CYP2A1 mRNA
CTD
PMID:19483382
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
Omeprazole results in increased expression of CYP2B1 mRNA; Omeprazole results in increased expression of CYP2B1 protein
CTD
PMID:9152597 PMID:19118567
NCBI chr 1:90,646,098...90,669,762
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression affects expression
EXP
Omeprazole results in increased expression of CYP2B2 protein Omeprazole affects the expression of CYP2B2 mRNA
CTD
PMID:9152597 PMID:19483382
NCBI chr 1:90,722,243...90,736,272
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression increases activity increases expression decreases activity
EXP ISO
Omeprazole affects the expression of CYP2B3 mRNA Omeprazole results in increased activity of CYP2B6 protein Omeprazole results in increased expression of CYP2B6 mRNA Omeprazole results in decreased activity of CYP2B10 protein
CTD
PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704
NCBI chr 1:90,780,468...90,859,852
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases metabolic processing affects metabolic processing increases metabolic processing increases hydroxylation multiple interactions decreases activity
ISO
CYP2C19 gene alternative form results in decreased metabolism of Omeprazole CYP2C19 protein affects the metabolism of Omeprazole CYP2C19 protein results in increased metabolism of Omeprazole CYP2C19 protein results in increased hydroxylation of Omeprazole [5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel]
CTD
PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 PMID:12485723 PMID:12637241 PMID:14586384 PMID:15258107 PMID:15286053 PMID:15306208 PMID:15626586 PMID:16035375 PMID:17565714 PMID:17702393 PMID:18511451 PMID:18520598 PMID:19812348 PMID:20573087 PMID:21277363 PMID:21795468 PMID:21915887 PMID:22634058 PMID:26599973 PMID:31515991 More...
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
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Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
increases expression
EXP
Omeprazole results in increased expression of CYP2D9 mRNA
CTD
PMID:19118567
NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479
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Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Omeprazole affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:115,797,789...115,802,158
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression decreases activity
EXP ISO
Omeprazole affects the expression of CYP2D4 mRNA Omeprazole results in decreased activity of CYP2D6 protein
CTD
PMID:18420780 PMID:19483382
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein
CTD
PMID:15802389 PMID:36243147
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Omeprazole affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
EXP
Omeprazole affects the expression of CYP2J4 mRNA
CTD
PMID:19483382
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
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Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Omeprazole affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:91,574,572...91,579,215
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
affects metabolic processing increases expression multiple interactions increases metabolic processing
ISO
CYP3A4 protein affects the metabolism of Omeprazole Omeprazole results in increased expression of CYP3A4 mRNA; Omeprazole results in increased expression of CYP3A4 protein [Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]; Omeprazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Omeprazole results in increased expression of and results in increased activity of CYP3A4 protein CYP3A4 protein results in increased metabolism of Omeprazole
CTD
PMID:7870052 PMID:8930576 PMID:9744552 PMID:12235278 PMID:12485723 PMID:12695340 PMID:15286053 PMID:15466163 PMID:15626586 PMID:15802389 PMID:17041008 PMID:17565714 PMID:17954527 PMID:19118567 PMID:19299527 PMID:22634058 More...
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression increases expression
EXP
Omeprazole affects the expression of CYP3A23-3A1 mRNA Omeprazole results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:19118567 PMID:19483382
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression increases expression
EXP ISO
Omeprazole affects the expression of CYP3A9 mRNA Omeprazole results in increased expression of CYP3A5 mRNA
CTD
PMID:19118567 PMID:19483382
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
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Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Omeprazole affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:133,938,883...133,970,226
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Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Omeprazole affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
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Dbi
diazepam binding inhibitor
affects expression
EXP
Omeprazole affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
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Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Omeprazole affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672
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Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Omeprazole affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,504,730...106,506,619
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Omeprazole results in increased expression of DDIT3 protein
CTD
PMID:27358234
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Omeprazole affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
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Dexi
Dexi homolog
affects expression
EXP
Omeprazole affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648
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Dgat1
diacylglycerol O-acyltransferase 1
affects expression
EXP
Omeprazole affects the expression of DGAT1 mRNA
CTD
PMID:19483382
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
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Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Omeprazole affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
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Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Omeprazole affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:32,936,522...32,948,101
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Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Omeprazole affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:45,504,344...45,537,094
Ensembl chr10:46,003,845...46,036,499
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Dhx16
DEAH-box helicase 16
affects expression
EXP
Omeprazole affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
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Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Omeprazole affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression
EXP
Omeprazole affects the expression of DNAJC3 mRNA
CTD
PMID:19483382
NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
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Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Omeprazole affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
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Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Omeprazole affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
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Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Omeprazole affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:176,597,986...176,625,848
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Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Omeprazole affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
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Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Omeprazole affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
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Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Omeprazole affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
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Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Omeprazole affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
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Egf
epidermal growth factor
multiple interactions
ISO
Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein]
CTD
PMID:18431645
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
EXP
Omeprazole affects the expression of EHHADH mRNA
CTD
PMID:19483382
NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
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Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Omeprazole affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
affects expression
EXP
Omeprazole affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
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Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Omeprazole affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:27,719,321...27,736,346
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Enc1
ectodermal-neural cortex 1
affects expression
EXP
Omeprazole affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
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Eno1
enolase 1
affects expression
EXP
Omeprazole affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
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Enpep
glutamyl aminopeptidase
affects expression
EXP
Omeprazole affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
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Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Omeprazole affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
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Ep300
E1A binding protein p300
multiple interactions
ISO
Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]
CTD
PMID:21703235
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
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Epcam
epithelial cell adhesion molecule
affects expression
EXP
Omeprazole affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
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Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Omeprazole affects the expression of ERP29 mRNA
CTD
PMID:19483382
NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
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Esd
esterase D
affects expression
EXP
Omeprazole affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
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Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Omeprazole affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:102,988,499...103,002,659
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Faah
fatty acid amide hydrolase
affects expression
EXP
Omeprazole affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
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Fads2
fatty acid desaturase 2
affects expression
EXP
Omeprazole affects the expression of FADS2 mRNA
CTD
PMID:19483382
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
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Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Omeprazole affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
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Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression
EXP
Omeprazole affects the expression of FDFT1 mRNA
CTD
PMID:19483382
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
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Fdps
farnesyl diphosphate synthase
affects expression
EXP
Omeprazole affects the expression of FDPS mRNA
CTD
PMID:19483382
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
G
Fdx2
ferredoxin 2
affects expression
EXP
Omeprazole affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015
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Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Omeprazole affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
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Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Omeprazole affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:10,098,571...10,102,083
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Omeprazole affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
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Gast
gastrin
increases expression
ISO EXP
Omeprazole results in increased expression of GAST protein
CTD
PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 PMID:17652263 More...
NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
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Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Omeprazole affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
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Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Omeprazole affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
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Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Omeprazole affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:38,326,594...38,349,647
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Ggt1
gamma-glutamyltransferase 1
multiple interactions
EXP
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA
CTD
PMID:22687989
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
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Gjb1
gap junction protein, beta 1
affects expression
EXP
Omeprazole affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
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Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Omeprazole affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,512,660...40,554,975
G
Gpx1
glutathione peroxidase 1
affects expression
EXP
Omeprazole affects the expression of GPX1 mRNA
CTD
PMID:19483382
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx2
glutathione peroxidase 2
multiple interactions
EXP
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA
CTD
PMID:22687989
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
G
Gpx4
glutathione peroxidase 4
affects expression
EXP
Omeprazole affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Omeprazole affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
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Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Omeprazole affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:78,517,052...78,522,861
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Gsta5
glutathione S-transferase alpha 5
increases expression multiple interactions
EXP
Omeprazole results in increased expression of GSTA5 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
CTD
PMID:17202759 PMID:22687989
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
G
Gstp1
glutathione S-transferase pi 1
increases expression
EXP
Omeprazole results in increased expression of GSTP1 mRNA
CTD
PMID:19118567
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Omeprazole affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
G
Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Omeprazole affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
G
Gulo
gulonolactone (L-) oxidase
affects expression
EXP
Omeprazole affects the expression of GULO mRNA
CTD
PMID:19483382
NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422
G
Gzma
granzyme A
affects expression
EXP
Omeprazole affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
G
H3f3b
H3.3 histone B
affects expression
EXP
Omeprazole affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
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Hal
histidine ammonia lyase
affects expression
EXP
Omeprazole affects the expression of HAL mRNA
CTD
PMID:19483382
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
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Hamp
hepcidin antimicrobial peptide
increases expression increases secretion multiple interactions
ISO
Omeprazole results in increased expression of HAMP mRNA Omeprazole results in increased secretion of HAMP protein Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]
CTD
PMID:31669099
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Omeprazole affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
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Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Omeprazole affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
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Hbb
hemoglobin subunit beta
affects expression
EXP
Omeprazole affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
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Hdc
histidine decarboxylase
affects expression multiple interactions increases expression increases stability
EXP
Omeprazole affects the expression of HDC mRNA Omeprazole results in increased expression of and results in increased activity of HDC protein Omeprazole results in increased expression of HDC mRNA Omeprazole results in increased stability of HDC protein
CTD
PMID:12763636 PMID:19483382
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Omeprazole affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
G
Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Omeprazole affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
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Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein
CTD
PMID:16712795 PMID:27725188
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Omeprazole affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Omeprazole affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:106,417,902...106,452,859
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Omeprazole affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:45,515,373...45,604,467
G
Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Omeprazole affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
decreases expression multiple interactions
EXP
Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
CTD
PMID:15223672 PMID:16945336
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
G
Hspa1l
heat shock protein family A (Hsp70) member 1 like
multiple interactions
EXP
Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA]
CTD
PMID:25637687
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
G
Htra1
HtrA serine peptidase 1
affects expression
EXP
Omeprazole affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
G
Ier3
immediate early response 3
multiple interactions
ISO
[Omeprazole co-treated with CCKBR protein] results in increased expression of IER3
CTD
PMID:17704804
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
G
Ifng
interferon gamma
multiple interactions
ISO
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
CTD
PMID:19232345
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Igf1
insulin-like growth factor 1
affects expression
EXP
Omeprazole affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
G
Igfals
insulin-like growth factor binding protein, acid labile subunit
affects expression
EXP
Omeprazole affects the expression of IGFALS mRNA
CTD
PMID:19483382
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Omeprazole affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
G
Il10
interleukin 10
multiple interactions
ISO EXP
Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein]
CTD
PMID:26970604 PMID:38341112
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
G
Il16
interleukin 16
multiple interactions
EXP
Omeprazole inhibits the reaction [Ethanol results in increased expression of IL16 protein]
CTD
PMID:38341112
NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023
G
Il1b
interleukin 1 beta
multiple interactions
EXP
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein]
CTD
PMID:32418911
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
multiple interactions
EXP ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein] Omeprazole inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD
PMID:25637687 PMID:32418911 PMID:38341112
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Impa1
inositol monophosphatase 1
affects expression
EXP
Omeprazole affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:93,370,299...93,391,468
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Omeprazole affects the expression of INHBE mRNA
CTD
PMID:19483382
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
G
Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Omeprazole affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,873,121...18,875,955
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Omeprazole affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
G
Jak1
Janus kinase 1
affects expression
EXP
Omeprazole affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Omeprazole affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:16,252,424...16,270,719
G
Kdr
kinase insert domain receptor
affects expression multiple interactions
EXP ISO
Omeprazole affects the expression of KDR mRNA Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]
CTD
PMID:19483382 PMID:26272953
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
G
Krt8
keratin 8
affects expression
EXP
Omeprazole affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
G
Lcat
lecithin cholesterol acyltransferase
affects expression
EXP
Omeprazole affects the expression of LCAT mRNA
CTD
PMID:19483382
NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
G
Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Omeprazole affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516
G
Lipc
lipase C, hepatic type
affects expression
EXP
Omeprazole affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
G
Lox
lysyl oxidase
affects expression
EXP
Omeprazole affects the expression of LOX mRNA
CTD
PMID:19483382
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
G
Lrp3
LDL receptor related protein 3
affects expression
EXP
Omeprazole affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:96,981,815...96,996,057
G
Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Omeprazole affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246
G
Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Omeprazole affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
G
Mapk14
mitogen activated protein kinase 14
multiple interactions
ISO
Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]
CTD
PMID:17406807
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
G
Masp2
MBL associated serine protease 2
affects expression
EXP
Omeprazole affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705
G
Me1
malic enzyme 1
affects expression multiple interactions
EXP
Omeprazole affects the expression of ME1 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA
CTD
PMID:19483382 PMID:22687989
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
G
Mmp14
matrix metallopeptidase 14
multiple interactions
EXP
Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein]
CTD
PMID:16934674
NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
G
Mmp2
matrix metallopeptidase 2
multiple interactions
EXP
Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein]
CTD
PMID:16934674
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
G
Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Omeprazole affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
G
Mpo
myeloperoxidase
multiple interactions decreases activity
ISO EXP
Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein] Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] Omeprazole results in decreased activity of MPO protein
CTD
PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 PMID:29770154 PMID:31095933 PMID:33245926 More...
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
G
Mro
maestro
affects expression
EXP
Omeprazole affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:69,725,798...69,743,031
G
Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Omeprazole affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:21,830,834...21,834,607
Ensembl chr 9:21,830,835...21,834,641
G
Mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Omeprazole affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777
G
Mug2
murinoglobulin 2
affects expression
EXP
Omeprazole affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:155,164,061...155,236,894
G
Myadm
myeloid-associated differentiation marker
affects expression
EXP
Omeprazole affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:74,775,698...74,789,710
G
Mycbp2
MYC binding protein 2
affects expression
EXP
Omeprazole affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
G
Myo1d
myosin ID
affects expression
EXP
Omeprazole affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,975,122...66,263,958
G
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Omeprazole affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715
G
Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Omeprazole affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
G
Nat8
N-acetyltransferase 8
affects expression
EXP
Omeprazole affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
G
Ncoa1
nuclear receptor coactivator 1
multiple interactions
ISO
Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
CTD
PMID:21703235
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
G
Ndrg2
NDRG family member 2
affects expression
EXP
Omeprazole affects the expression of NDRG2 mRNA
CTD
PMID:19483382
NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
G
Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Omeprazole affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909 Ensembl chr 5:184,849,197...185,028,909 Ensembl chr14:184,849,197...185,028,909
G
Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Omeprazole affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
G
Neu2
neuraminidase 2
affects expression
EXP
Omeprazole affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:95,696,507...95,715,208
G
Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]
CTD
PMID:27725188
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
EXP
Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein]
CTD
PMID:32418911
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
G
Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Omeprazole affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
G
Nipal2
NIPA-like domain containing 2
affects expression
EXP
Omeprazole affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:67,659,628...67,769,959
G
Nit1
nitrilase 1
affects expression
EXP
Omeprazole affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
G
Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
EXP
Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]
CTD
PMID:32418911
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Omeprazole affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:78,898,097...78,903,514
Ensembl chr20:11,179,066...11,179,497 Ensembl chr10:11,179,066...11,179,497
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
EXP ISO
Omeprazole results in increased expression of NQO1 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein]
CTD
PMID:17202759 PMID:22687989 PMID:26272953
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions increases activity
ISO EXP
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]
CTD
PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression increases expression decreases metabolic processing
EXP ISO
Omeprazole affects the expression of NR1I3 mRNA Omeprazole results in increased expression of NR1I3 mRNA NR1I3 gene mutant form results in decreased metabolism of Omeprazole
CTD
PMID:19118567 PMID:19483382 PMID:27434302
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Omeprazole affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
G
Oaf
out at first homolog
affects expression
EXP
Omeprazole affects the expression of OAF mRNA
CTD
PMID:19483382
NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
G
Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Omeprazole affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
G
Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Omeprazole affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
G
Olr59
olfactory receptor 59
affects expression
EXP
Omeprazole affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:166,604,141...166,623,265
G
Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Omeprazole affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:221,874,948...221,940,267
G
Otc
ornithine transcarbamylase
affects expression
EXP
Omeprazole affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555
G
Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Omeprazole affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Omeprazole affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
G
Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
Omeprazole results in increased cleavage of PARP1 protein
CTD
PMID:15461867
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
G
Pc
pyruvate carboxylase
affects expression
EXP
Omeprazole affects the expression of PCX mRNA
CTD
PMID:19483382
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:211,228,731...211,329,940
G
Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Omeprazole affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:110,469,934...110,520,187
G
Pcna
proliferating cell nuclear antigen
multiple interactions
EXP ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein] Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]
CTD
PMID:19251492 PMID:26970604
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Omeprazole affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:128,839,232...129,052,128
G
Pctp
phosphatidylcholine transfer protein
affects expression
EXP
Omeprazole affects the expression of PCTP mRNA
CTD
PMID:19483382
NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
G
Pdcl3
phosducin-like 3
affects expression
EXP
Omeprazole affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:48,723,767...48,739,529
G
Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Omeprazole affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:128,841,917...128,867,327
G
Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Omeprazole affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
G
Pex19
peroxisomal biogenesis factor 19
affects expression
EXP
Omeprazole affects the expression of PEX19 mRNA
CTD
PMID:19483382
NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
G
Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Omeprazole affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
G
Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Omeprazole affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
G
Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Omeprazole affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Omeprazole affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082
G
Pklr
pyruvate kinase L/R
affects expression
EXP
Omeprazole affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
G
Pla2g4a
phospholipase A2 group 4A
increases phosphorylation multiple interactions
ISO
Omeprazole results in increased phosphorylation of PLA2G4A protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]
CTD
PMID:25797602
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
G
Plbd1
phospholipase B domain containing 1
affects expression
EXP
Omeprazole affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:171,204,198...171,260,488
G
Plg
plasminogen
affects expression
EXP
Omeprazole affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
G
Pls3
plastin 3
affects expression
EXP
Omeprazole affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
G
Pon2
paraoxonase 2
affects expression
EXP
Omeprazole affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996
G
Pou2f2
POU class 2 homeobox 2
multiple interactions
EXP ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein]
CTD
PMID:30452898
NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Omeprazole affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:188,676,965...188,678,599
G
Prdx2
peroxiredoxin 2
affects expression
EXP
Omeprazole affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
G
Prdx6
peroxiredoxin 6
affects expression
EXP
Omeprazole affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
G
Prl
prolactin
increases expression
ISO
Omeprazole results in increased expression of PRL protein
CTD
PMID:20726208
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
G
Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Omeprazole affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
G
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Omeprazole affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Omeprazole affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:78,500,736...78,531,717
G
Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Omeprazole affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Omeprazole affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
G
Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Omeprazole affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:125,122,490...125,134,858
G
Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Omeprazole affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:97,487,632...97,499,176
G
Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Omeprazole affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Omeprazole affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Omeprazole affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP ISO
[Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]
CTD
PMID:23038005 PMID:26970604
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Ptms
parathymosin
affects expression
EXP
Omeprazole affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Omeprazole affects the expression of PTPRF mRNA
CTD
PMID:19483382
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
G
Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Omeprazole affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909
G
Pygl
glycogen phosphorylase L
affects expression
EXP
Omeprazole affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
G
Rab5if
RAB5 interacting factor
affects expression
EXP
Omeprazole affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
EXP ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]
CTD
PMID:19251492 PMID:30452898 PMID:32418911
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Retsat
retinol saturase
increases expression
EXP
Omeprazole results in increased expression of RETSAT mRNA
CTD
PMID:25626140
NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:106,211,436...106,229,552
G
Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Omeprazole affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692
G
Rnase4
ribonuclease A family member 4
affects expression
EXP
Omeprazole affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
G
Rnf103
ring finger protein 103
affects expression
EXP
Omeprazole affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:105,084,686...105,106,809
G
Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Omeprazole affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
G
Rpl11
ribosomal protein L11
affects expression
EXP
Omeprazole affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
G
Rpl13
ribosomal protein L13
affects expression
EXP
Omeprazole affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
G
Rpl15
ribosomal protein L15
affects expression
EXP
Omeprazole affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
G
Rpl17
ribosomal protein L17
affects expression
EXP
Omeprazole affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638 Ensembl chr18:111,722,010...111,722,638
G
Rpl23
ribosomal protein L23
affects expression
EXP
Omeprazole affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
G
Rpl3
ribosomal protein L3
affects expression
EXP
Omeprazole affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
G
Rpl32
ribosomal protein L32
affects expression
EXP
Omeprazole affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:150,536,646...150,540,214
G
Rpl4
ribosomal protein L4
affects expression
EXP
Omeprazole affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
G
Rpn2
ribophorin II
affects expression
EXP
Omeprazole affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:166,361,955...166,409,272
Ensembl chr 3:166,362,049...166,409,922
G
Rps14
ribosomal protein S14
affects expression
EXP
Omeprazole affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
G
Rps18
ribosomal protein S18
affects expression
EXP
Omeprazole affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423
G
Rps19
ribosomal protein S19
affects expression
EXP
Omeprazole affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132 Ensembl chr 1:104,324,520...104,325,132
G
Rps20
ribosomal protein S20
affects expression
EXP
Omeprazole affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621 Ensembl chr 9:42,839,965...43,095,621 Ensembl chr 5:42,839,965...43,095,621
G
Rps3a
ribosomal protein S3a
affects expression
EXP
Omeprazole affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
G
Rps6
ribosomal protein S6
affects expression
EXP
Omeprazole affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
G
Rps8
ribosomal protein S8
affects expression
EXP
Omeprazole affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
G
Rras2
RAS related 2
affects expression
EXP
Omeprazole affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
G
RT1-DMa
RT1 class II, locus DMa
affects expression
ISO
Omeprazole affects the expression of HLA-DMA mRNA
CTD
PMID:25811541
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,708,933...4,712,335
G
RT1-M3-1
RT1 class Ib, locus M3, gene 1
affects expression
ISO
Omeprazole affects the expression of HLA-G mRNA
CTD
PMID:25811541
NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366
G
RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Omeprazole affects the expression of RT1-S3 mRNA
CTD
PMID:19483382
NCBI chr20:2,675,463...2,680,229
G
S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Omeprazole affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
G
Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Omeprazole affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:8,185,985...8,218,898
G
Sdc2
syndecan 2
affects expression
EXP
Omeprazole affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294
G
Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Omeprazole affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044
G
Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Omeprazole affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:59,841,090...59,850,641
Ensembl chr 8:59,841,090...59,850,641
G
Sell
selectin L
decreases expression
EXP
Omeprazole results in decreased expression of SELL protein
CTD
PMID:17652263
NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
G
Serinc3
serine incorporator 3
affects expression
EXP
Omeprazole affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
G
Serpina1
serpin family A member 1
affects expression
EXP
Omeprazole affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
G
Serpina10
serpin family A member 10
affects expression
EXP
Omeprazole affects the expression of SERPINA10 mRNA
CTD
PMID:19483382
NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332
G
Serpina4
serpin family A member 4
affects expression
EXP
Omeprazole affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
G
Serpinf2
serpin family F member 2
affects expression
EXP
Omeprazole affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
G
Serping1
serpin family G member 1
decreases expression
EXP
Omeprazole results in decreased expression of SERPING1 mRNA
CTD
PMID:25626140
NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
G
Sfxn1
sideroflexin 1
affects expression
EXP
Omeprazole affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
G
Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Omeprazole affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Omeprazole affects the expression of SLC22A1 mRNA
CTD
PMID:19483382
NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
G
Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
G
Slc22a5
solute carrier family 22 member 5
multiple interactions
EXP
Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]
CTD
PMID:19041296
NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077
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Slc22a8
solute carrier family 22 member 8
multiple interactions
ISO
[Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican
CTD
PMID:36243147
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
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Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Omeprazole affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702
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Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Omeprazole affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:35,145,721...35,328,360
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Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Omeprazole affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:27,499,165...27,506,309
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Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Omeprazole affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
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Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Omeprazole affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:226,929,644...226,992,667
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Slc40a1
solute carrier family 40 member 1
decreases expression
ISO
Omeprazole results in decreased expression of SLC40A1 protein
CTD
PMID:31669099
NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
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Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Omeprazole affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
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Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Omeprazole affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:73,702,472...73,739,678
Ensembl chr18:75,977,458...76,014,651
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Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Omeprazole affects the expression of SLC6A6 mRNA
CTD
PMID:19483382
NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
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Slco1a1
solute carrier organic anion transporter family, member 1a1
affects expression
EXP
Omeprazole affects the expression of SLCO1A1 mRNA
CTD
PMID:19483382
NCBI chr 4:174,877,045...174,950,900
Ensembl chr 4:176,607,687...176,681,992
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Slco1a4
solute carrier organic anion transporter family, member 1a4
increases expression
ISO
Omeprazole results in increased expression of SLCO1A2 mRNA
CTD
PMID:19118567
NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
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Sod1
superoxide dismutase 1
multiple interactions
ISO
Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein]
CTD
PMID:28849987
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
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Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Omeprazole affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:134,605,750...134,646,752
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Srm
spermidine synthase
affects expression
EXP
Omeprazole affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
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Srprb
SRP receptor subunit beta
affects expression
EXP
Omeprazole affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:112,647,577...112,661,524
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Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Omeprazole affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Omeprazole affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:55,530,248...55,598,720
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Omeprazole affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
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Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression
EXP
Omeprazole affects the expression of SUCLG1 mRNA
CTD
PMID:19483382
NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:106,866,114...106,895,689
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Surf4
surfeit 4
affects expression
EXP
Omeprazole affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:30,646,435...30,659,641
Ensembl chr 3:30,638,299...30,661,390
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Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Omeprazole affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:106,920,970...106,966,543
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Tacr1
tachykinin receptor 1
multiple interactions
ISO
Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein]
CTD
PMID:16091555
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:116,478,617...116,647,492
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
Omeprazole results in increased expression of TGFB1 protein
CTD
PMID:36243147
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Omeprazole affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
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Thnsl2
threonine synthase-like 2
affects expression
EXP
Omeprazole affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:104,670,925...104,691,959
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Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Omeprazole affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:78,314,900...78,319,362
Ensembl chr18:80,589,783...80,594,237
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Timp2
TIMP metallopeptidase inhibitor 2
multiple interactions
EXP
Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein]
CTD
PMID:16934674
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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Tkfc
triokinase and FMN cyclase
affects expression
EXP
Omeprazole affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
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Tlr4
toll-like receptor 4
multiple interactions
EXP
Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]
CTD
PMID:32418911
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Omeprazole affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657
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Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
EXP
Omeprazole affects the expression of TEGT mRNA
CTD
PMID:19483382
NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
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Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Omeprazole affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
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Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Omeprazole affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606
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Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Omeprazole affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:41,505,167...41,512,243
Ensembl chr18:41,478,539...41,512,243
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Tmem123
transmembrane protein 123
affects expression
EXP
Omeprazole affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
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Tmem97
transmembrane protein 97
affects expression
EXP
Omeprazole affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818
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Tnf
tumor necrosis factor
multiple interactions
ISO EXP
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein] Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD
PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 PMID:38341112 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Txn1
thioredoxin 1
affects expression
EXP
Omeprazole affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
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Txnl1
thioredoxin-like 1
affects expression
EXP
Omeprazole affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
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Tyr
tyrosinase
multiple interactions decreases expression
ISO
Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] Omeprazole results in decreased expression of TYR protein
CTD
PMID:25337692
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Omeprazole affects the expression of UBA52 mRNA
CTD
PMID:19483382
NCBI chr16:18,952,583...18,954,780
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Omeprazole affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:32,041,190...32,071,252
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Omeprazole affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases expression affects expression
ISO EXP
Omeprazole results in increased expression of UGT1A1 mRNA Omeprazole affects the expression of UGT1A1 mRNA
CTD
PMID:19118567 PMID:19483382 PMID:25626140
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
increases expression
ISO
Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA
CTD
PMID:19118567
NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a3
UDP glycosyltransferase 1 family, polypeptide A3
increases expression
ISO
Omeprazole results in increased expression of UGT1A5 mRNA
CTD
PMID:19118567
NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a5
UDP glucuronosyltransferase family 1 member A5
increases expression
ISO
Omeprazole results in increased expression of UGT1A4 mRNA
CTD
PMID:19118567
NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases expression multiple interactions
EXP ISO
Omeprazole results in increased expression of UGT1A6 mRNA [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
CTD
PMID:19118567 PMID:22687989
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases expression
ISO
Omeprazole results in increased expression of UGT1A9 mRNA
CTD
PMID:19118567
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
increases expression
EXP
Omeprazole results in increased expression of UGT2B1 mRNA
CTD
PMID:25626140
NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
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Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Omeprazole affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,955,764...9,959,047
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Vnn1
vanin 1
affects expression
EXP
Omeprazole affects the expression of VNN1 mRNA
CTD
PMID:19483382
NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
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Wdr26
WD repeat domain 26
affects expression
EXP
Omeprazole affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:95,462,020...95,503,738
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Omeprazole affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Omeprazole affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:70,225,045...70,240,102
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Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Omeprazole affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
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