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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:esomeprazole
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Accession:CHEBI:50275 term browser browse the term
Definition:A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.
Synonyms:exact_synonym: 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
 related_synonym: (-)-omeprazole;   (S)-omeprazole;   Alenia;   Escz;   Esofag;   Formula=C17H19N3O3S;   InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1;   InChIKey=SUBDBMMJDZJVOS-DEOSSOPVSA-N;   Inexium paranova;   SMILES=COc1ccc2[nH]c(nc2c1)[S@@](=O)Cc1ncc(C)c(OC)c1C;   esomeprazol;   esomeprazolum
 xref: CAS:119141-88-7;   DrugBank:DB00736;   Drug_Central:1055;   HMDB:HMDB0005009;   HMDB:HMDB0014874;   KEGG:D07917
 xref_mesh: MESH:D064098
 xref: PMID:10983736;   PMID:15080761;   PMID:18407713;   PMID:18472988;   PMID:23677700;   Reaxys:12060639;   Wikipedia:Esomeprazole
 cyclic_relationship: is_conjugate_acid_of CHEBI:77264;   is_enantiomer_of CHEBI:77262



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esomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Mycophenolic Acid promotes the reaction [Esomeprazole results in increased expression of CYP1A1 mRNA] CTD PMID:25929522 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
omeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Omeprazole results in increased expression of ABCA1 mRNA CTD PMID:20060385 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Omeprazole results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of ABCB1A mRNA
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein]
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
CTD PMID:19483382 PMID:30452898 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein CTD PMID:35447140 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Omeprazole results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Omeprazole affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein
Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]
CTD PMID:20804740 PMID:31348918 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression EXP Omeprazole affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Omeprazole affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Omeprazole affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Omeprazole affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression EXP Omeprazole affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Omeprazole affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP
ISO
Omeprazole results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Aco1 aconitase 1 affects expression EXP Omeprazole affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 affects expression EXP Omeprazole affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression EXP Omeprazole affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Omeprazole affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Omeprazole affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Add1 adducin 1 affects expression EXP Omeprazole affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Omeprazole affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Omeprazole affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Afm afamin affects expression EXP Omeprazole affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Agt angiotensinogen affects expression EXP Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases response to substance
affects localization
decreases expression
increases expression
increases activity
decreases activity
ISO
EXP
AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein]
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
AHR protein results in increased susceptibility to Omeprazole
Omeprazole affects the localization of AHR protein
Omeprazole results in decreased activity of AHR protein
CTD PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression
multiple interactions
EXP Omeprazole affects the expression of AKR7A3 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ALDH1A1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Omeprazole results in increased expression of ALDH1A3 mRNA CTD PMID:12040753 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Omeprazole affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO Omeprazole results in increased expression of ALDH3A1 mRNA CTD PMID:12040753 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Omeprazole affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression EXP Omeprazole results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Omeprazole affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Omeprazole affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Omeprazole affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoh apolipoprotein H affects expression EXP Omeprazole affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Omeprazole affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:77,377,723...77,443,672
Ensembl chr  X:77,377,781...77,443,900
JBrowse link
G Arg1 arginase 1 affects expression EXP Omeprazole affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Omeprazole affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
affects localization
ISO
EXP
Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]
Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
Omeprazole affects the localization of ARNT protein
CTD PMID:9395520 PMID:21703235 PMID:25826687 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Omeprazole affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Omeprazole affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Omeprazole affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Omeprazole affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Omeprazole affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
CTD PMID:25337692 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Omeprazole affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:30452898 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:30452898 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Omeprazole affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression EXP Omeprazole affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Omeprazole affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmx BMX non-receptor tyrosine kinase multiple interactions ISO BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein] CTD PMID:21861773 NCBI chr  X:30,227,251...30,290,015
Ensembl chr  X:30,227,251...30,289,993
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Omeprazole affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Omeprazole affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C1qa complement C1q A chain decreases expression EXP Omeprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Omeprazole affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Omeprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G C1s complement C1s affects expression EXP Omeprazole affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Omeprazole affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression
decreases expression
EXP Omeprazole affects the expression of C4BPA mRNA
Omeprazole results in decreased expression of C4BPA mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Omeprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G C7 complement C7 affects expression EXP Omeprazole affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8b complement C8 beta chain affects expression EXP Omeprazole affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Omeprazole affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Omeprazole affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Omeprazole affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car3 carbonic anhydrase 3 affects expression EXP Omeprazole affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
affects expression
multiple interactions
ISO
EXP
Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein
Omeprazole results in increased cleavage of CASP3 protein
Omeprazole affects the expression of CASP3 mRNA
Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
CTD PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP
ISO
Omeprazole results in increased activity of CAT protein
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein]
Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:18547560 PMID:28849987 PMID:33245926 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Omeprazole affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Omeprazole results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Omeprazole affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Omeprazole affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Omeprazole affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfi complement factor I affects expression
decreases expression
EXP Omeprazole affects the expression of CFI mRNA
Omeprazole results in decreased expression of CFI mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
G Cftr CF transmembrane conductance regulator affects metabolic processing ISO CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Omeprazole affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Omeprazole affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Omeprazole affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Omeprazole affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Omeprazole affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression EXP Omeprazole affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Omeprazole affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Omeprazole affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Omeprazole affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression EXP Omeprazole affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Omeprazole affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Omeprazole affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Omeprazole affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Omeprazole affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Omeprazole affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Omeprazole affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Omeprazole affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctsb cathepsin B decreases activity ISO Omeprazole results in decreased activity of CTSB protein CTD PMID:34871754 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein] CTD PMID:20165931 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctse cathepsin E decreases expression EXP Omeprazole results in decreased expression of CTSE CTD PMID:7575556 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions
ISO Omeprazole results in decreased expression of CXCR4 mRNA
AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]
CTD PMID:25826687 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
increases expression
decreases activity
ISO
EXP
Omeprazole results in increased activity of CYP1A1 promoter
Omeprazole results in increased activity of CYP1A1 protein
AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]
Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]
Omeprazole results in decreased activity of CYP1A1 protein
Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA]
CTD PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
decreases activity
multiple interactions
increases expression
ISO
EXP
Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein
Omeprazole results in decreased activity of CYP1A2 protein
[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein
Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA
CTD PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
decreases activity
affects expression
ISO Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
Omeprazole results in increased expression of CYP1B1 mRNA
Omeprazole results in decreased activity of CYP1B1 protein
Omeprazole affects the expression of CYP1B1 mRNA
CTD PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Omeprazole results in increased expression of CYP2B1 mRNA; Omeprazole results in increased expression of CYP2B1 protein CTD PMID:9152597 PMID:19118567 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
affects expression
EXP Omeprazole results in increased expression of CYP2B2 protein
Omeprazole affects the expression of CYP2B2 mRNA
CTD PMID:9152597 PMID:19483382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
increases activity
increases expression
decreases activity
EXP
ISO
Omeprazole affects the expression of CYP2B3 mRNA
Omeprazole results in increased activity of CYP2B6 protein
Omeprazole results in increased expression of CYP2B6 mRNA
Omeprazole results in decreased activity of CYP2B10 protein
CTD PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions ISO Omeprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:15258107 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases metabolic processing
affects metabolic processing
increases metabolic processing
increases hydroxylation
multiple interactions
decreases activity
ISO CYP2C19 gene alternative form results in decreased metabolism of Omeprazole
CYP2C19 protein affects the metabolism of Omeprazole
CYP2C19 protein results in increased metabolism of Omeprazole
CYP2C19 protein results in increased hydroxylation of Omeprazole
[5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel]
CTD PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Omeprazole affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
decreases activity
EXP
ISO
Omeprazole affects the expression of CYP2D4 mRNA
Omeprazole results in decreased activity of CYP2D6 protein
CTD PMID:18420780 PMID:19483382 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 PMID:36243147 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
increases expression
multiple interactions
increases metabolic processing
ISO CYP3A4 protein affects the metabolism of Omeprazole
Omeprazole results in increased expression of CYP3A4 mRNA; Omeprazole results in increased expression of CYP3A4 protein
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]; Omeprazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Omeprazole results in increased expression of and results in increased activity of CYP3A4 protein
CYP3A4 protein results in increased metabolism of Omeprazole
CTD PMID:7870052 PMID:8930576 PMID:9744552 PMID:12235278 PMID:12485723 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
increases expression
EXP Omeprazole affects the expression of CYP3A23-3A1 mRNA
Omeprazole results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
increases expression
EXP
ISO
Omeprazole affects the expression of CYP3A9 mRNA
Omeprazole results in increased expression of CYP3A5 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Omeprazole affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Omeprazole affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP Omeprazole affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Omeprazole affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Omeprazole affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Omeprazole results in increased expression of DDIT3 protein CTD PMID:27358234 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Omeprazole affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dexi Dexi homolog affects expression EXP Omeprazole affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression EXP Omeprazole affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Omeprazole affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Omeprazole affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Omeprazole affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Omeprazole affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Omeprazole affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression EXP Omeprazole affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Omeprazole affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Omeprazole affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Omeprazole affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Omeprazole affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Omeprazole affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Omeprazole affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Omeprazole affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein] CTD PMID:18431645 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression EXP Omeprazole affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Omeprazole affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression EXP Omeprazole affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Omeprazole affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Omeprazole affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eno1 enolase 1 affects expression EXP Omeprazole affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Omeprazole affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Omeprazole affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Omeprazole affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Omeprazole affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esd esterase D affects expression EXP Omeprazole affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Omeprazole affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Omeprazole affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP Omeprazole affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Omeprazole affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Omeprazole affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Omeprazole affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Omeprazole affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Omeprazole affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Omeprazole affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gast gastrin increases expression ISO
EXP
Omeprazole results in increased expression of GAST protein CTD PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 More... NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Omeprazole affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Omeprazole affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Omeprazole affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA CTD PMID:22687989 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Omeprazole affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Omeprazole affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Omeprazole affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA CTD PMID:22687989 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Omeprazole affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Omeprazole affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Omeprazole affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression
multiple interactions
EXP Omeprazole results in increased expression of GSTA5 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
CTD PMID:17202759 PMID:22687989 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Omeprazole results in increased expression of GSTP1 mRNA CTD PMID:19118567 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Omeprazole affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Omeprazole affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Gzma granzyme A affects expression EXP Omeprazole affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Omeprazole affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Omeprazole affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression
increases secretion
multiple interactions
ISO Omeprazole results in increased expression of HAMP mRNA
Omeprazole results in increased secretion of HAMP protein
Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]
CTD PMID:31669099 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Omeprazole affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Omeprazole affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Omeprazole affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hdc histidine decarboxylase affects expression
multiple interactions
increases expression
increases stability
EXP Omeprazole affects the expression of HDC mRNA
Omeprazole results in increased expression of and results in increased activity of HDC protein
Omeprazole results in increased expression of HDC mRNA
Omeprazole results in increased stability of HDC protein
CTD PMID:12763636 PMID:19483382 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Omeprazole affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Omeprazole affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein
Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein
CTD PMID:16712795 PMID:27725188 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Omeprazole affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Omeprazole affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Omeprazole affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions
EXP Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein
Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
CTD PMID:15223672 PMID:16945336 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Omeprazole affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifng interferon gamma multiple interactions ISO Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] CTD PMID:19232345 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression EXP Omeprazole affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Omeprazole affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein] CTD PMID:32418911 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein] CTD PMID:25637687 PMID:32418911 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Omeprazole affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Inhbe inhibin subunit beta E affects expression EXP Omeprazole affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Omeprazole affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Omeprazole affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Omeprazole affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdr kinase insert domain receptor affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of KDR mRNA
Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]
CTD PMID:19483382 PMID:26272953 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Krt8 keratin 8 affects expression EXP Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Omeprazole affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Omeprazole affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Omeprazole affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lox lysyl oxidase affects expression EXP Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Omeprazole affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Omeprazole affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein] CTD PMID:17406807 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Omeprazole affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
G Me1 malic enzyme 1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ME1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein] CTD PMID:16934674 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein] CTD PMID:16934674 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Omeprazole affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO
EXP
Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein]
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Omeprazole results in decreased activity of MPO protein
CTD PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 More... NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mro maestro affects expression EXP Omeprazole affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Omeprazole affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Omeprazole affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
JBrowse link
G Mug2 murinoglobulin 2 affects expression EXP Omeprazole affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Omeprazole affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Omeprazole affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Myo1d myosin ID affects expression EXP Omeprazole affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Omeprazole affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Omeprazole affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Omeprazole affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP Omeprazole affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Omeprazole affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
Ensembl chr14:135,974,034...135,979,603
Ensembl chr 2:135,974,034...135,979,603
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Omeprazole affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Omeprazole affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein] CTD PMID:27725188 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein] CTD PMID:32418911 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Omeprazole affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Omeprazole affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Omeprazole affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Omeprazole affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP
ISO
Omeprazole results in increased expression of NQO1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA
Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein]
CTD PMID:17202759 PMID:22687989 PMID:26272953 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO
EXP
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA] CTD PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression
increases expression
decreases metabolic processing
EXP
ISO
Omeprazole affects the expression of NR1I3 mRNA
Omeprazole results in increased expression of NR1I3 mRNA
NR1I3 gene mutant form results in decreased metabolism of Omeprazole
CTD PMID:19118567 PMID:19483382 PMID:27434302 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Omeprazole affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Oaf out at first homolog affects expression EXP Omeprazole affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Omeprazole affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Omeprazole affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Omeprazole affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Omeprazole affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Omeprazole affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Omeprazole affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Omeprazole affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Omeprazole results in increased cleavage of PARP1 protein CTD PMID:15461867 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Omeprazole affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Omeprazole affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein]
Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]
CTD PMID:19251492 PMID:26970604 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP Omeprazole affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Omeprazole affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Omeprazole affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Omeprazole affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression EXP Omeprazole affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Omeprazole affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Omeprazole affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Omeprazole affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Omeprazole affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Omeprazole affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases phosphorylation
multiple interactions
ISO Omeprazole results in increased phosphorylation of PLA2G4A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]
CTD PMID:25797602 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Omeprazole affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
JBrowse link
G Plg plasminogen affects expression EXP Omeprazole affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pls3 plastin 3 affects expression EXP Omeprazole affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Omeprazole affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions EXP
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein] CTD PMID:30452898 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Omeprazole affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Omeprazole affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prl prolactin increases expression ISO Omeprazole results in increased expression of PRL protein CTD PMID:20726208 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Omeprazole affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Omeprazole affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Omeprazole affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Omeprazole affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Omeprazole affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Omeprazole affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Omeprazole affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Omeprazole affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Omeprazole affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 affects expression EXP Omeprazole affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
[Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein
Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]
CTD PMID:23038005 PMID:26970604 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptms parathymosin affects expression EXP Omeprazole affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Omeprazole affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Omeprazole affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Omeprazole affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Omeprazole affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]
Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]
CTD PMID:19251492 PMID:30452898 PMID:32418911 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Retsat retinol saturase increases expression EXP Omeprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Omeprazole affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Omeprazole affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Omeprazole affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Omeprazole affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Omeprazole affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Omeprazole affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Omeprazole affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Omeprazole affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Omeprazole affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Omeprazole affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Omeprazole affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Omeprazole affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpn2 ribophorin II affects expression EXP Omeprazole affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Omeprazole affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Omeprazole affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Omeprazole affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Omeprazole affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Omeprazole affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Omeprazole affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Omeprazole affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rras2 RAS related 2 affects expression EXP Omeprazole affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G RT1-DMa RT1 class II, locus DMa affects expression ISO Omeprazole affects the expression of HLA-DMA mRNA CTD PMID:25811541 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Omeprazole affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Omeprazole affects the expression of RT1-S3 mRNA CTD PMID:19483382 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Omeprazole affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Omeprazole affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Omeprazole affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Omeprazole affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Omeprazole affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
G Sell selectin L decreases expression EXP Omeprazole results in decreased expression of SELL protein CTD PMID:17652263 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Omeprazole affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Omeprazole affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpina10 serpin family A member 10 affects expression EXP Omeprazole affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Omeprazole affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Omeprazole affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP Omeprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Omeprazole affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Omeprazole affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression EXP Omeprazole affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions EXP Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine] CTD PMID:19041296 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Omeprazole affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Omeprazole affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Omeprazole affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Omeprazole affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Omeprazole affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO Omeprazole results in decreased expression of SLC40A1 protein CTD PMID:31669099 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Omeprazole affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Omeprazole affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Omeprazole affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO Omeprazole results in increased expression of SLCO1A2 mRNA CTD PMID:19118567 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein] CTD PMID:28849987 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Omeprazole affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
JBrowse link
G Srm spermidine synthase affects expression EXP Omeprazole affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Omeprazole affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:103,768,685...103,782,632 JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Omeprazole affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Omeprazole affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression EXP Omeprazole affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
JBrowse link
G Surf4 surfeit 4 affects expression EXP Omeprazole affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Omeprazole affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Omeprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Omeprazole affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Omeprazole affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Omeprazole affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein] CTD PMID:16934674 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Omeprazole affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein] CTD PMID:32418911 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Omeprazole affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Omeprazole affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Omeprazole affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Omeprazole affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Omeprazole affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Omeprazole affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]
Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Omeprazole affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Omeprazole affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Tyr tyrosinase multiple interactions
decreases expression
ISO Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole results in decreased expression of TYR protein
CTD PMID:25337692 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Omeprazole affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Omeprazole affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Omeprazole affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
affects expression
ISO
EXP
Omeprazole results in increased expression of UGT1A1 mRNA
Omeprazole affects the expression of UGT1A1 mRNA
CTD PMID:19118567 PMID:19483382 PMID:25626140 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 increases expression ISO Omeprazole results in increased expression of UGT1A5 mRNA CTD PMID:19118567 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases expression ISO Omeprazole results in increased expression of UGT1A4 mRNA CTD PMID:19118567 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
multiple interactions
EXP
ISO
Omeprazole results in increased expression of UGT1A6 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
CTD PMID:19118567 PMID:22687989 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO Omeprazole results in increased expression of UGT1A9 mRNA CTD PMID:19118567 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Omeprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Omeprazole affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
JBrowse link
G Vnn1 vanin 1 affects expression EXP Omeprazole affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Omeprazole affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Omeprazole affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Omeprazole affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Omeprazole affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        pharmacological role 19111
          antagonist 17213
            histamine antagonist 4894
              esomeprazole 407
                omeprazole + 407
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  organic heteropolycyclic compound 18334
                                    organic heterobicyclic compound 17279
                                      benzimidazoles 1178
                                        5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole 407
                                          esomeprazole 407
                                            omeprazole + 407
paths to the root