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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11476
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Acc ID: CHEBI:7772
Term: omeprazole
Definition: A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
Chemical ID: MESH:D009853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:39356480464CTDOmeprazole affects the expression of UGT1A1 mRNA

PMID:19483382
increases expressionISORGD:13500186480464CTDOmeprazole results in increased expression of UGT1A1 mRNA

PMID:19118567
increases expressionISORGD:39356480464CTDOmeprazole results in increased expression of UGT1A1 mRNA

PMID:25626140
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.