Thnsl2 (threonine synthase-like 2 (bacterial)) - Rat Genome Database
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Gene: Thnsl2 (threonine synthase-like 2 (bacterial)) Mus musculus
Analyze
Symbol: Thnsl2
Name: threonine synthase-like 2 (bacterial)
RGD ID: 1319322
MGI Page MGI
Description: Is expressed in renal calyx. Orthologous to human THNSL2 (threonine synthase like 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC051244; MGC59076; mTSH2; threonine synthase-like 2; TSH; TSH2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,105,150 - 71,121,364 (-)NCBIGRCm39mm39
GRCm39 Ensembl671,105,150 - 71,121,423 (-)Ensembl
GRCm38671,128,166 - 71,144,380 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,128,166 - 71,144,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv37671,078,392 - 71,094,370 (-)NCBIGRCm37mm9NCBIm37
MGSCv36671,057,977 - 71,073,955 (-)NCBImm8
Celera673,207,460 - 73,223,442 (-)NCBICelera
Cytogenetic Map6C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17034760   PMID:21267068   PMID:21873635  
PMID:32325033  


Genomics

Comparative Map Data
Thnsl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,105,150 - 71,121,364 (-)NCBIGRCm39mm39
GRCm39 Ensembl671,105,150 - 71,121,423 (-)Ensembl
GRCm38671,128,166 - 71,144,380 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,128,166 - 71,144,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv37671,078,392 - 71,094,370 (-)NCBIGRCm37mm9NCBIm37
MGSCv36671,057,977 - 71,073,955 (-)NCBImm8
Celera673,207,460 - 73,223,442 (-)NCBICelera
Cytogenetic Map6C1NCBI
THNSL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl288,170,274 - 88,186,636 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl288,170,295 - 88,186,636 (+)EnsemblGRCh38hg38GRCh38
GRCh38288,170,346 - 88,186,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37288,469,865 - 88,486,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36288,250,950 - 88,267,261 (+)NCBINCBI36hg18NCBI36
Celera288,299,987 - 88,316,198 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef287,392,048 - 87,408,933 (+)NCBIHuRef
CHM1_1288,399,093 - 88,415,447 (+)NCBICHM1_1
Thnsl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24103,112,974 - 103,132,122 (-)NCBI
Rnor_6.0 Ensembl498,976,550 - 98,995,590 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0498,976,559 - 98,997,187 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04163,753,102 - 163,773,190 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,329,517 - 104,348,465 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14104,573,999 - 104,592,946 (-)NCBI
Celera492,288,587 - 92,307,161 (-)NCBICelera
Cytogenetic Map4q31NCBI
Thnsl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955424526,602 - 543,603 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955424526,967 - 543,603 (-)NCBIChiLan1.0ChiLan1.0
THNSL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A89,212,380 - 89,228,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,212,442 - 89,228,446 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A87,303,022 - 87,319,494 (+)NCBIMhudiblu_PPA_v0panPan3
THNSL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1738,191,494 - 38,212,809 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11738,196,605 - 38,212,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Thnsl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936712684,711 - 699,714 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THNSL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl357,799,026 - 57,823,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1357,800,976 - 57,821,296 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,654,264 - 60,669,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THNSL2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11418,603,376 - 18,619,711 (-)NCBI
ChlSab1.1 Ensembl1418,600,437 - 18,619,762 (-)Ensembl
Thnsl2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474916,198,423 - 16,229,952 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268671322775Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
14746995Manh60_mmandible shape 60 (mouse)63722567771225677Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64089129671379171Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64160000075600000Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64211637376116515Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64211637376116515Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64211637376116515Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64211637376116515Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64382681377811523Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64382681377811523Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64382681377811523Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64382681377811523Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64382681377811523Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64382681377811523Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4872655675447710Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:563
Count of miRNA genes:313
Interacting mature miRNAs:343
Transcripts:ENSMUST00000074241, ENSMUST00000160918, ENSMUST00000170455, ENSMUST00000170753
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000074241   ⟹   ENSMUSP00000073861
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,128,398 - 71,144,347 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160918   ⟹   ENSMUSP00000124423
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,128,166 - 71,144,439 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170455
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,131,766 - 71,144,331 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170753   ⟹   ENSMUSP00000129994
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl671,128,656 - 71,131,972 (-)Ensembl
RefSeq Acc Id: NM_001033929   ⟹   NP_001029101
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39671,105,150 - 71,121,364 (-)NCBI
GRCm38671,128,166 - 71,144,380 (-)NCBI
MGSCv37671,078,392 - 71,094,370 (-)RGD
Celera673,207,228 - 73,223,446 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_178413   ⟹   NP_848500
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39671,105,150 - 71,121,364 (-)NCBI
GRCm38671,128,166 - 71,144,380 (-)NCBI
MGSCv37671,078,392 - 71,094,370 (-)RGD
Celera673,207,228 - 73,223,446 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001029101   ⟸   NM_001033929
- UniProtKB: Q80W22 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_848500   ⟸   NM_178413
- UniProtKB: Q80W22 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000073861   ⟸   ENSMUST00000074241
RefSeq Acc Id: ENSMUSP00000129994   ⟸   ENSMUST00000170753
RefSeq Acc Id: ENSMUSP00000124423   ⟸   ENSMUST00000160918

Promoters
RGD ID:6840065
Promoter ID:MM_KWN:46411
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001033929,   NM_178413
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36671,093,924 - 71,094,424 (-)MPROMDB
RGD ID:6889948
Promoter ID:EPDNEW_M8425
Type:multiple initiation site
Name:Thnsl2_1
Description:Mus musculus threonine synthase-like 2 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38671,144,347 - 71,144,407EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3041254 AgrOrtholog
Ensembl Genes ENSMUSG00000054474 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000073861 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124423 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000129994 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074241 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000160918 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000170753 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1380.10 UniProtKB/Swiss-Prot
InterPro PLP-dep UniProtKB/Swiss-Prot
  Thr_synth_N UniProtKB/Swiss-Prot
  Thr_synth_N_sf UniProtKB/Swiss-Prot
  Thr_synthase-like UniProtKB/Swiss-Prot
  Trypto_synt_PLP_dependent UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:232078 UniProtKB/Swiss-Prot
MGD MGI:3041254 ENTREZGENE
NCBI Gene 232078 ENTREZGENE
Pfam PALP UniProtKB/Swiss-Prot
  Thr_synth_N UniProtKB/Swiss-Prot
PhenoGen Thnsl2 PhenoGen
Superfamily-SCOP SSF53686 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs thrC UniProtKB/Swiss-Prot
UniProt F7AFM3_MOUSE UniProtKB/TrEMBL
  Q80W22 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8R135 UniProtKB/Swiss-Prot