Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | St3gal6 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ST3GAL6 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ST3GAL6 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ST3GAL6 mRNA | CTD | PMID:19484750 | 17beta-estradiol | increases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of ST3GAL6 mRNA | CTD | PMID:32145629 | 17beta-estradiol | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ST3GAL6 mRNA | CTD | PMID:20660070 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ST3GAL6 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ST3GAL6 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ST3GAL6 mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ST3GAL6 mRNA | CTD | PMID:21570461 and PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ST3GAL6 mRNA | CTD | PMID:21215274 | 2,6-dinitrotoluene | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of ST3GAL6 mRNA | CTD | PMID:21346803 | 2-butoxyethanol | increases expression | EXP | | 6480464 | n-butoxyethanol results in increased expression of ST3GAL6 mRNA | CTD | PMID:19812364 | 2-palmitoylglycerol | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ST3GAL6 mRNA | CTD | PMID:37199045 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of ST3GAL6 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of ST3GAL6 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Decitabine inhibits the reaction [Smoke results in decreased expression of ST3GAL6 mRNA] | CTD | PMID:21095227 | 5-azacytidine | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of ST3GAL6 mRNA | CTD | PMID:19194470 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Propylthiouracil affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | 8-Br-cAMP | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ST3GAL6 mRNA | CTD | PMID:22079614 | acrylamide | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of ST3GAL6 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ST3GAL6 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ST3GAL6 mRNA | CTD | PMID:21934132 more ... | amiodarone | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Amiodarone affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | antirheumatic drug | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ST3GAL6 mRNA | CTD | PMID:24449571 | atrazine | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ST3GAL6 mRNA | CTD | PMID:22378314 | benzbromarone | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Benzbromarone affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | decreases methylation | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ST3GAL6 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ST3GAL6 5' UTR | CTD | PMID:27901495 | beta-naphthoflavone | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in increased expression of ST3GAL6 mRNA | CTD | PMID:19737606 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ST3GAL6 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ST3GAL6 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of ST3GAL6 mRNA | CTD | PMID:30951980 | cadmium dichloride | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of ST3GAL6 mRNA | CTD | PMID:33453195 | calcitriol | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of ST3GAL6 mRNA | CTD | PMID:16002434 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of ST3GAL6 mRNA | CTD | PMID:37019170 | clofibrate | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Clofibrate affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | cocaine | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Cocaine results in increased expression of ST3GAL6 mRNA | CTD | PMID:12629581 | copper(II) sulfate | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ST3GAL6 mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of ST3GAL6 mRNA | CTD | PMID:25351596 | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of ST3GAL6 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ST3GAL6 mRNA | CTD | PMID:20106945 and PMID:25562108 | cytarabine | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of ST3GAL6 mRNA | CTD | PMID:21198554 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:29950665 | dibutyl phthalate | increases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of ST3GAL6 mRNA | CTD | PMID:21266533 | disodium selenite | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of ST3GAL6 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST3GAL6 mRNA | CTD | PMID:27188386 | doxorubicin | affects expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of ST3GAL6 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of ST3GAL6 mRNA | CTD | PMID:29391264 | ethyl methanesulfonate | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ST3GAL6 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:22206623 | fulvestrant | increases methylation | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of ST3GAL6 gene | CTD | PMID:31601247 | furan | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | furan results in decreased expression of ST3GAL6 mRNA | CTD | PMID:26194646 | gentamycin | increases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of ST3GAL6 mRNA | CTD | PMID:33387578 | L-ethionine | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Ethionine affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | leflunomide | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | leflunomide results in increased expression of ST3GAL6 mRNA | CTD | PMID:28988120 | lipopolysaccharide | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:35811015 | menadione | affects expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ST3GAL6 mRNA | CTD | PMID:20044591 | methapyrilene | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of ST3GAL6 mRNA | CTD | PMID:30467583 | methyl methanesulfonate | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ST3GAL6 mRNA | CTD | PMID:23649840 | nickel sulfate | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of ST3GAL6 mRNA | CTD | PMID:22714537 | nimesulide | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | nimesulide results in decreased expression of ST3GAL6 mRNA | CTD | PMID:24136188 | omeprazole | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ST3GAL6 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ST3GAL6 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of ST3GAL6 mRNA | CTD | PMID:33387578 | PD 0325901 | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:25119042 | PD 0325901 | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | mirdametinib results in decreased expression of ST3GAL6 mRNA | CTD | PMID:25119042 | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of ST3GAL6 mRNA | CTD | PMID:37995155 | pirinixic acid | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | pirinixic acid affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ST3GAL6 mRNA | CTD | PMID:17426115 more ... | progesterone | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ST3GAL6 mRNA | CTD | PMID:20660070 | rimonabant | multiple interactions | EXP | | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA] | CTD | PMID:19030233 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST3GAL6 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ST3GAL6 mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of ST3GAL6 mRNA | CTD | PMID:25351596 | sodium arsenite | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ST3GAL6 mRNA | CTD | PMID:22714537 more ... | sodium arsenite | affects methylation | ISO | ST3GAL6 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of ST3GAL6 gene | CTD | PMID:28589171 | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of ST3GAL6 mRNA | CTD | PMID:21641980 | sunitinib | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ST3GAL6 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of ST3GAL6 mRNA | CTD | PMID:21669218 | testosterone enanthate | affects expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of ST3GAL6 mRNA | CTD | PMID:17440010 | tetrachloromethane | multiple interactions | ISO | St3gal6 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ST3GAL6 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of ST3GAL6 mRNA | CTD | PMID:31150632 | thioacetamide | affects expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Thioacetamide affects the expression of ST3GAL6 mRNA | CTD | PMID:19483382 | thioacetamide | decreases expression | ISO | St3gal6 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ST3GAL6 mRNA | CTD | PMID:34492290 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ST3GAL6 mRNA | CTD | PMID:29950665 | trichostatin A | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ST3GAL6 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | ST3GAL6 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST3GAL6 mRNA | CTD | PMID:27188386 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ST3GAL6 mRNA | CTD | PMID:33045310 | urethane | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ST3GAL6 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ST3GAL6 mRNA | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ST3GAL6 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ST3GAL6 mRNA | CTD | PMID:25979313 | zebularine | increases expression | ISO | ST3GAL6 (Homo sapiens) | 6480464 | pyrimidin-2-one beta-ribofuranoside results in increased expression of ST3GAL6 mRNA | CTD | PMID:19194470 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
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Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - KEGG (archival)
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Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10619706 | PMID:10894948 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:12477932 | PMID:14681479 | PMID:15489334 | PMID:15782199 | PMID:16141072 |
| PMID:16141073 | PMID:18287559 | PMID:21267068 | PMID:21677750 | PMID:21873635 | PMID:22700726 | PMID:22967998 | PMID:24154525 | PMID:30308156 | PMID:37752945 |
Genomics
Comparative Map Data
| St3gal6 (Mus musculus - house mouse) |
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| ST3GAL6 (Homo sapiens - human) |
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| St3gal6 (Rattus norvegicus - Norway rat) |
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| St3gal6 (Chinchilla lanigera - long-tailed chinchilla) |
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| ST3GAL6 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ST3GAL6 (Canis lupus familiaris - dog) |
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| St3gal6 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ST3GAL6 (Sus scrofa - pig) |
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| ST3GAL6 (Chlorocebus sabaeus - green monkey) |
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| St3gal6 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in St3gal6
1536 total Variants 
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