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Gene: C8b (complement component 8, beta polypeptide) Mus musculus
Symbol: C8b
Name: complement component 8, beta polypeptide
RGD ID: 10264
Description: Predicted to be involved in complement activation, alternative pathway; complement activation, classical pathway; and cytolysis. Predicted to localize to extracellular space and membrane attack complex. Is expressed in brain; liver and biliary system; stomach; and testis. Human ortholog(s) of this gene implicated in type II complement component 8 deficiency. Orthologous to human C8B (complement C8 beta chain).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4930439B20Rik; AI595927; complement component 8 subunit beta; complement component 8, beta subunit; complement component C8 beta chain
Homo sapiens (human) : C8B (complement C8 beta chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : C8b (complement C8 beta chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C8b (complement C8 beta chain)
Pan paniscus (bonobo/pygmy chimpanzee) : C8B (complement C8 beta chain)
Canis lupus familiaris (dog) : C8B (complement C8 beta chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C8b (complement C8 beta chain)
Sus scrofa (pig) : C8B (complement C8 beta chain)
Chlorocebus sabaeus (African green monkey) : C8B (complement C8 beta chain)
Heterocephalus glaber (naked mole-rat) : C8b (complement C8 beta chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4104,766,317 - 104,804,548 (+)EnsemblGRCm38mm10GRCm38
GRCm384104,766,317 - 104,804,548 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374104,438,922 - 104,477,153 (+)NCBIGRCm37mm9NCBIm37
MGSCv364104,264,249 - 104,302,480 (+)NCBImm8
Celera4103,118,327 - 103,156,421 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map448.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on C8b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10264
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.