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Gene: Ufd1 (ubiquitin recognition factor in ER-associated degradation 1) Mus musculus
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Symbol: Ufd1
Name: ubiquitin recognition factor in ER-associated degradation 1
Description: Exhibits K48-linked polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ERAD pathway and regulation of cytokine production. Localizes to UFD1-NPL4 complex and VCP-NPL4-UFD1 AAA ATPase complex. Is expressed in several structures, including brain; branchial arch; cardiovascular system; limb; and sensory organ. Human ortholog(s) of this gene implicated in DiGeorge syndrome and schizophrenia. Orthologous to human UFD1 (ubiquitin recognition factor in ER associated degradation 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1H-pyrazole; Aroclor 1254; calyculin a.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: UB fusion protein 1; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation protein 1 homolog; ubiquitin recognition factor in ER-associated degradation protein 1; Ufd1l
Orthologs:
Related Pseudogenes: Gm18738  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1618,811,779 - 18,835,261 (+)EnsemblGRCm38mm10GRCm38
GRCm381618,811,736 - 18,835,261 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371618,812,387 - 18,835,354 (+)NCBIGRCm37mm9NCBIm37
MGSCv361618,725,889 - 18,748,818 (+)NCBImm8
Celera1619,386,351 - 19,409,318 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Ufd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732949
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.