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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzimidazoles
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Accession:CHEBI:22715 term browser browse the term
Definition:An organic heterocyclic compound containing a benzene ring fused to an imidazole ring.
Synonyms:alt_id: MESH:D001562
 xref_mesh: MESH:D001562



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benzimidazoles term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Benzimidazoles promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] CTD PMID:8647108 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Benzimidazoles analog binds to DRD2 protein CTD PMID:21509803 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding EXP Benzimidazoles analog binds to HTR2A protein CTD PMID:21509803 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions
decreases response to substance
ISO Benzimidazoles inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]
Benzimidazoles results in decreased susceptibility to IGF2 protein
CTD PMID:24055520 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 multiple interactions ISO [Benzimidazoles analog results in increased activity of [KCNQ3 protein binds to KCNQ2 protein]] which results in increased import of Thallium; [Benzimidazoles analog results in increased activity of KCNQ2 protein] which results in increased import of Thallium; Benzimidazoles analog results in increased activity of [KCNQ3 protein binds to KCNQ2 protein] CTD PMID:21723881 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 multiple interactions ISO [Benzimidazoles analog results in increased activity of [KCNQ3 protein binds to KCNQ2 protein]] which results in increased import of Thallium; Benzimidazoles analog results in increased activity of [KCNQ3 protein binds to KCNQ2 protein] CTD PMID:21723881 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity EXP Benzimidazoles results in decreased activity of MTR protein CTD PMID:17222188 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541
JBrowse link
G Sts steroid sulfatase multiple interactions ISO Benzimidazoles inhibits the reaction [IGF2 protein results in increased expression of STS mRNA] CTD PMID:24055520 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO Benzimidazoles results in decreased activity of TOP2A protein CTD PMID:20884089 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
1H-benzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 increases stability EXP benzimidazole results in increased stability of EPAS1 protein CTD PMID:23545307 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]] CTD PMID:16135784 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021
JBrowse link
1H-benzo[d]imidazole-2-thiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2-mercaptobenzimidazole analog results in increased expression of CYP1A1 protein; 2-mercaptobenzimidazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO bisbenzimide ethoxide trihydrochloride inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride
ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride
abamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased export of bisbenzimide ethoxide trihydrochloride; abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
CTD PMID:25865432 PMID:34896433 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases transport
ISO abamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] CTD PMID:25865432 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases abundance
decreases export
decreases activity
multiple interactions
increases export
increases transport
ISO ABCG2 protein results in decreased abundance of bisbenzimide ethoxide trihydrochloride
ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride
bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCG2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased export of bisbenzimide ethoxide trihydrochloride; [bisphenol A results in decreased activity of ABCG2 protein] which results in decreased transport of bisbenzimide ethoxide trihydrochloride; [MLN 8237 affects the activity of ABCG2 protein] which affects the export of bisbenzimide ethoxide trihydrochloride; [MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride; Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]; Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Porphyrins inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Tobacco Smoke Pollution inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; verlukast inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
CTD PMID:12869632 PMID:19239227 PMID:26850786 PMID:26907376 PMID:27450509 More... NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases export ISO KEAP1 protein results in decreased export of bisbenzimide ethoxide trihydrochloride CTD PMID:25841332 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride CTD PMID:19239227 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
2-aminobenzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2-aminobenzimidazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in increased expression of ABCB1 protein] CTD PMID:16121039 PMID:20513373 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression
multiple interactions
ISO Dichlororibofuranosylbenzimidazole results in decreased expression of ABL1 protein
Bortezomib promotes the reaction [Dichlororibofuranosylbenzimidazole results in decreased expression of ABL1 protein]
CTD PMID:15039284 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] CTD PMID:12917420 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
ISO Dexamethasone inhibits the reaction [Dichlororibofuranosylbenzimidazole results in increased expression of BCL2L1 protein] CTD PMID:9326359 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]] CTD PMID:17295206 PMID:18636177 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [romidepsin results in increased expression of CDKN1A protein] CTD PMID:15014036 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Methoxsalen results in increased expression of CES2 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CES2 mRNA] CTD PMID:17003103 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein] CTD PMID:16121039 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA] CTD PMID:15962303 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]] CTD PMID:17295206 PMID:18636177 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] CTD PMID:12917420 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]] CTD PMID:25233930 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Methoxsalen results in increased expression of CYP3A4 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:17003103 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Fbl fibrillarin affects localization ISO Dichlororibofuranosylbenzimidazole analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [TNF protein results in increased expression of HIF1A protein] CTD PMID:12479793 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Hemin results in increased activity of HMOX1 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Hemin results in increased expression of HMOX1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Hemin results in increased expression of HMOX1 protein] CTD PMID:16109301 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions
affects localization
ISO Dichlororibofuranosylbenzimidazole affects the reaction [HNRNPA1 protein binds to CYP2A5 mRNA]
Dichlororibofuranosylbenzimidazole affects the localization of HNRNPA1 protein
CTD PMID:12754101 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions EXP Dichlororibofuranosylbenzimidazole inhibits the reaction [Glycine results in increased expression of HNRNPK mRNA] CTD PMID:24990929 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:11295263 PMID:12185005 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]] CTD PMID:23589332 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA] CTD PMID:15142038 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200
JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
JBrowse link
G Nelfa negative elongation factor complex member A multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr14:81,033,470...81,057,546
Ensembl chr14:81,033,514...81,058,719
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein] CTD PMID:21569845 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Dichlororibofuranosylbenzimidazole co-treated with Bortezomib] results in increased cleavage of PARP1 protein CTD PMID:15039284 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Polr2a RNA polymerase II subunit A decreases phosphorylation
multiple interactions
ISO Dichlororibofuranosylbenzimidazole results in decreased phosphorylation of POLR2A protein
Bortezomib promotes the reaction [Dichlororibofuranosylbenzimidazole results in decreased phosphorylation of POLR2A protein]; sodium arsenite inhibits the reaction [Dichlororibofuranosylbenzimidazole results in decreased phosphorylation of POLR2A protein]
CTD PMID:8126066 PMID:15039284 PMID:24102143 NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179
JBrowse link
G Rgn regucalcin multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RGN mRNA] CTD PMID:18327666 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:15962303 PMID:18327666 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Cadmium Chloride results in increased expression of SLC30A1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA] CTD PMID:15142038 NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892
JBrowse link
G Slc38a2 solute carrier family 38, member 2 affects expression ISO Dichlororibofuranosylbenzimidazole affects the expression of SLC38A2 protein CTD PMID:15581851 NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Dichlororibofuranosylbenzimidazole affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
Dichlororibofuranosylbenzimidazole inhibits the reaction [TNF protein results in increased expression of HIF1A protein]
Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]]
CTD PMID:11295263 PMID:12185005 PMID:12479793 PMID:25233930 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of TNFSF11 mRNA] CTD PMID:17295206 PMID:18327666 PMID:18636177 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO Dichlororibofuranosylbenzimidazole results in increased phosphorylation of TP53 protein CTD PMID:24102143 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO Dichlororibofuranosylbenzimidazole inhibits the reaction [Fluorouracil results in increased expression of TYMS protein] CTD PMID:23056627 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Dichlororibofuranosylbenzimidazole inhibits the reaction [Oxygen deficiency results in increased phosphorylation of and results in increased activity of XDH protein] CTD PMID:11278616 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
JBrowse link
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Omeprazole results in increased expression of ABCA1 mRNA CTD PMID:20060385 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Omeprazole results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of ABCB1A mRNA
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein]
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
CTD PMID:19483382 PMID:30452898 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein CTD PMID:35447140 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Omeprazole results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Omeprazole affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein
Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]
CTD PMID:20804740 PMID:31348918 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression EXP Omeprazole affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Omeprazole affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Omeprazole affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Omeprazole affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,775,016...9,781,447 JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression EXP Omeprazole affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Omeprazole affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO
EXP
Omeprazole results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596
JBrowse link
G Aco1 aconitase 1 affects expression EXP Omeprazole affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
JBrowse link
G Aco2 aconitase 2 affects expression EXP Omeprazole affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression EXP Omeprazole affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Omeprazole affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Omeprazole affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
JBrowse link
G Add1 adducin 1 affects expression EXP Omeprazole affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Omeprazole affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Omeprazole affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622
JBrowse link
G Afm afamin affects expression EXP Omeprazole affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
JBrowse link
G Agt angiotensinogen affects expression EXP Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases activity
increases activity
increases expression
decreases expression
affects localization
increases response to substance
EXP
ISO
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
Omeprazole results in decreased activity of AHR protein
Omeprazole results in increased activity of AHR protein
Omeprazole results in increased expression of AHR protein
Omeprazole results in decreased expression of AHR mRNA
AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein]
Omeprazole affects the localization of AHR protein
AHR protein results in increased susceptibility to Omeprazole
CTD PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 More... NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression
multiple interactions
EXP Omeprazole affects the expression of AKR7A3 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ALDH1A1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Omeprazole results in increased expression of ALDH1A3 mRNA CTD PMID:12040753 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP Omeprazole affects the expression of ALDH1A7 mRNA CTD PMID:19483382 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Omeprazole affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO Omeprazole results in increased expression of ALDH3A1 mRNA CTD PMID:12040753 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Omeprazole affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Omeprazole affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Omeprazole affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Omeprazole affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
JBrowse link
G Apoh apolipoprotein H affects expression EXP Omeprazole affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Omeprazole affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:81,569,960...81,635,906
Ensembl chr  X:81,570,053...81,640,036
JBrowse link
G Arg1 arginase 1 affects expression EXP Omeprazole affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 affects expression EXP Omeprazole affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
affects localization
ISO
EXP
Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]
Omeprazole affects the localization of ARNT protein
Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
CTD PMID:9395520 PMID:21703235 PMID:25826687 NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Omeprazole affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Omeprazole affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Omeprazole affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Omeprazole affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Omeprazole affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
CTD PMID:25337692 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Omeprazole affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:30452898 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:30452898 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Omeprazole affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression EXP Omeprazole affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Omeprazole affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
JBrowse link
G Bmx BMX non-receptor tyrosine kinase multiple interactions ISO BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein] CTD PMID:21861773 NCBI chr  X:33,859,128...33,921,876
Ensembl chr  X:33,859,129...33,921,874
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Omeprazole affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Omeprazole affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125
Ensembl chr13:31,394,011...31,401,125
JBrowse link
G C1qa complement C1q A chain decreases expression EXP Omeprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Omeprazole affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Omeprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C1s complement C1s affects expression EXP Omeprazole affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Omeprazole affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:50,694,680...50,759,096
Ensembl chr11:50,694,563...50,759,016
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression
decreases expression
EXP Omeprazole affects the expression of C4BPA mRNA
Omeprazole results in decreased expression of C4BPA mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Omeprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
JBrowse link
G C7 complement C7 affects expression EXP Omeprazole affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
JBrowse link
G C8b complement C8 beta chain affects expression EXP Omeprazole affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Omeprazole affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Omeprazole affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Omeprazole affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Omeprazole affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
affects expression
increases cleavage
ISO
EXP
Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein
Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
Omeprazole affects the expression of CASP3 mRNA
Omeprazole results in increased cleavage of CASP3 protein
CTD PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP
ISO
Omeprazole results in increased activity of CAT protein
Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein]
CTD PMID:18547560 PMID:28849987 PMID:33245926 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Omeprazole affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Omeprazole results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Omeprazole affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Omeprazole affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:196,682,455...196,724,430
Ensembl chr 2:196,681,681...196,723,812
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Omeprazole affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
JBrowse link
G Cfi complement factor I affects expression
decreases expression
EXP Omeprazole affects the expression of CFI mRNA
Omeprazole results in decreased expression of CFI mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
JBrowse link
G Cftr CF transmembrane conductance regulator affects metabolic processing ISO CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Omeprazole affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Omeprazole affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Omeprazole affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:27,290,769...27,356,967
Ensembl chr  X:27,290,868...27,356,939
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Omeprazole affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Omeprazole affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression EXP Omeprazole affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Omeprazole affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Omeprazole affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Omeprazole affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,382,897...9,413,216
Ensembl chr14:9,382,900...9,413,107
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression EXP Omeprazole affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:40,226,368...40,257,617
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Omeprazole affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Omeprazole affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Omeprazole affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Omeprazole affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Omeprazole affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Omeprazole affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Omeprazole affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
JBrowse link
G Ctsb cathepsin B decreases activity ISO Omeprazole results in decreased activity of CTSB protein CTD PMID:34871754 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein] CTD PMID:20165931 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
JBrowse link
G Ctse cathepsin E decreases expression EXP Omeprazole results in decreased expression of CTSE CTD PMID:7575556 NCBI chr13:45,644,168...45,666,722
Ensembl chr13:45,644,147...45,666,722
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions
ISO Omeprazole results in decreased expression of CXCR4 mRNA
AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]
CTD PMID:25826687 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
decreases activity
ISO
EXP
AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]
Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA]
Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein
Omeprazole results in increased activity of CYP1A1 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]
Omeprazole results in decreased activity of CYP1A1 protein
Omeprazole results in increased activity of CYP1A1 promoter
CTD PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 More... NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
increases expression
increases activity
ISO
EXP
Omeprazole results in decreased activity of CYP1A2 protein
[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein
Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA
Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein
CTD PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 More... NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
affects expression
increases expression
decreases activity
ISO Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
Omeprazole affects the expression of CYP1B1 mRNA
Omeprazole results in increased expression of CYP1B1 mRNA
Omeprazole results in decreased activity of CYP1B1 protein
CTD PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Omeprazole results in increased expression of CYP2B1 mRNA; Omeprazole results in increased expression of CYP2B1 protein CTD PMID:9152597 PMID:19118567 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
increases expression
EXP Omeprazole affects the expression of CYP2B2 mRNA
Omeprazole results in increased expression of CYP2B2 protein
CTD PMID:9152597 PMID:19483382 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
decreases activity
increases expression
increases activity
EXP
ISO
Omeprazole affects the expression of CYP2B3 mRNA
Omeprazole results in decreased activity of CYP2B10 protein
Omeprazole results in increased expression of CYP2B6 mRNA
Omeprazole results in increased activity of CYP2B6 protein
CTD PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects metabolic processing
decreases activity
multiple interactions
increases metabolic processing
decreases metabolic processing
increases hydroxylation
ISO CYP2C19 protein affects the metabolism of Omeprazole
Omeprazole results in decreased activity of CYP2C19 protein
[5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel]
CYP2C19 protein results in increased metabolism of Omeprazole
CYP2C19 gene alternative form results in decreased metabolism of Omeprazole
CYP2C19 protein results in increased hydroxylation of Omeprazole
CTD PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 More... NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 increases expression EXP Omeprazole results in increased expression of CYP2D9 mRNA CTD PMID:19118567 NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Omeprazole affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:115,797,785...115,802,142
Ensembl chr 7:115,797,789...115,802,158
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
decreases activity
EXP
ISO
Omeprazole affects the expression of CYP2D4 mRNA
Omeprazole results in decreased activity of CYP2D6 protein
CTD PMID:18420780 PMID:19483382 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 PMID:36243147 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
increases metabolic processing
affects metabolic processing
ISO [Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]; Omeprazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Omeprazole results in increased expression of and results in increased activity of CYP3A4 protein
Omeprazole results in increased expression of CYP3A4 mRNA; Omeprazole results in increased expression of CYP3A4 protein
CYP3A4 protein results in increased metabolism of Omeprazole
CYP3A4 protein affects the metabolism of Omeprazole
CTD PMID:7870052 PMID:8930576 PMID:9744552 PMID:12235278 PMID:12485723 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
increases expression
EXP Omeprazole affects the expression of CYP3A23-3A1 mRNA
Omeprazole results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
increases expression
EXP
ISO
Omeprazole affects the expression of CYP3A9 mRNA
Omeprazole results in increased expression of CYP3A5 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Omeprazole affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Omeprazole affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP Omeprazole affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Omeprazole affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Omeprazole affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,504,730...106,506,619 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Omeprazole results in increased expression of DDIT3 protein CTD PMID:27358234 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Omeprazole affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
JBrowse link
G Dexi Dexi homolog affects expression EXP Omeprazole affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression EXP Omeprazole affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Omeprazole affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Omeprazole affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Omeprazole affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:46,003,845...46,036,498
Ensembl chr10:46,003,845...46,036,499
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Omeprazole affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Omeprazole affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression EXP Omeprazole affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Omeprazole affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Omeprazole affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Omeprazole affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:186,025,740...186,057,165 JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Omeprazole affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Omeprazole affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Omeprazole affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Omeprazole affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein] CTD PMID:18431645 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression EXP Omeprazole affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Omeprazole affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression EXP Omeprazole affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Omeprazole affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Omeprazole affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
JBrowse link
G Eno1 enolase 1 affects expression EXP Omeprazole affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Omeprazole affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Omeprazole affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Omeprazole affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Omeprazole affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
JBrowse link
G Esd esterase D affects expression EXP Omeprazole affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Omeprazole affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Omeprazole affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP Omeprazole affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Omeprazole affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Omeprazole affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Omeprazole affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Omeprazole affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Omeprazole affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Omeprazole affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gast gastrin increases expression ISO
EXP
Omeprazole results in increased expression of GAST protein CTD PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 More... NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Omeprazole affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Omeprazole affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Omeprazole affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA CTD PMID:22687989 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Omeprazole affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:70,541,862...70,549,843
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Omeprazole affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Omeprazole affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA CTD PMID:22687989 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Omeprazole affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Omeprazole affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Omeprazole affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression
EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
Omeprazole results in increased expression of GSTA5 mRNA
CTD PMID:17202759 PMID:22687989 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Omeprazole results in increased expression of GSTP1 mRNA CTD PMID:19118567 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Omeprazole affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Omeprazole affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
JBrowse link
G Gulo gulonolactone (L-) oxidase affects expression EXP Omeprazole affects the expression of GULO mRNA CTD PMID:19483382 NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422
JBrowse link
G Gzma granzyme A affects expression EXP Omeprazole affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Omeprazole affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Omeprazole affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
JBrowse link
G Hamp hepcidin antimicrobial peptide increases secretion
multiple interactions
increases expression
ISO Omeprazole results in increased secretion of HAMP protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]
Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein
CTD PMID:31669099 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Omeprazole affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Omeprazole affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Omeprazole affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
JBrowse link
G Hdc histidine decarboxylase affects expression
increases expression
increases stability
multiple interactions
EXP Omeprazole affects the expression of HDC mRNA
Omeprazole results in increased expression of HDC mRNA
Omeprazole results in increased stability of HDC protein
Omeprazole results in increased expression of and results in increased activity of HDC protein
CTD PMID:12763636 PMID:19483382 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Omeprazole affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Omeprazole affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein
Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein
CTD PMID:16712795 PMID:27725188 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Omeprazole affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:106,417,902...106,457,220
Ensembl chr 1:106,417,902...106,452,859
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Omeprazole affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Omeprazole affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
decreases expression
EXP Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein
CTD PMID:15223672 PMID:16945336 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Omeprazole affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
JBrowse link
G Ifng interferon gamma multiple interactions ISO Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] CTD PMID:19232345 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression EXP Omeprazole affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Omeprazole affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 PMID:38341112 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il16 interleukin 16 multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in increased expression of IL16 protein] CTD PMID:38341112 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein] CTD PMID:32418911 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein]
Omeprazole inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:25637687 PMID:32418911 PMID:38341112 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Omeprazole affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:93,370,200...93,391,474
Ensembl chr 2:93,370,299...93,391,468
JBrowse link
G Inhbe inhibin subunit beta E affects expression EXP Omeprazole affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Omeprazole affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Omeprazole affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Omeprazole affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:16,252,424...16,270,737
Ensembl chr12:16,252,424...16,270,719
JBrowse link
G Kdr kinase insert domain receptor affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of KDR mRNA
Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]
CTD PMID:19483382 PMID:26272953 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
JBrowse link
G Krt8 keratin 8 affects expression EXP Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Omeprazole affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Omeprazole affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Omeprazole affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
JBrowse link
G Lox lysyl oxidase affects expression EXP Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Omeprazole affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Omeprazole affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein] CTD PMID:17406807 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Omeprazole affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705
JBrowse link
G Me1 malic enzyme 1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ME1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein] CTD PMID:16934674 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein] CTD PMID:16934674 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Omeprazole affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO
EXP
Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein]
Omeprazole results in decreased activity of MPO protein
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein]
CTD PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 More... NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mro maestro affects expression EXP Omeprazole affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:69,723,764...69,742,815
Ensembl chr18:69,725,798...69,743,031
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Omeprazole affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:21,830,834...21,834,607
Ensembl chr 9:21,830,835...21,834,641
JBrowse link
G Mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Omeprazole affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777
JBrowse link
G Mug2 murinoglobulin 2 affects expression EXP Omeprazole affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:156,836,140...156,908,972 JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Omeprazole affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Omeprazole affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
JBrowse link
G Myo1d myosin ID affects expression EXP Omeprazole affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Omeprazole affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Omeprazole affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Omeprazole affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP Omeprazole affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Omeprazole affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909
Ensembl chr 5:184,849,197...185,028,909
Ensembl chr14:184,849,197...185,028,909
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Omeprazole affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Omeprazole affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:95,696,507...95,715,208
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein] CTD PMID:27725188 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein] CTD PMID:32418911 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Omeprazole affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Omeprazole affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:67,659,628...67,771,105
Ensembl chr 7:67,659,628...67,769,959
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Omeprazole affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Omeprazole affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP
ISO
Omeprazole results in increased expression of NQO1 mRNA
Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein]
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA
CTD PMID:17202759 PMID:22687989 PMID:26272953 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO
EXP
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA] CTD PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression
decreases metabolic processing
increases expression
EXP
ISO
Omeprazole affects the expression of NR1I3 mRNA
NR1I3 gene mutant form results in decreased metabolism of Omeprazole
Omeprazole results in increased expression of NR1I3 mRNA
CTD PMID:19118567 PMID:19483382 PMID:27434302 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Omeprazole affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
JBrowse link
G Oaf out at first homolog affects expression EXP Omeprazole affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Omeprazole affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Omeprazole affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Omeprazole affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Omeprazole affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Omeprazole affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:15,126,358...15,239,555
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Omeprazole affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Omeprazole affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Omeprazole results in increased cleavage of PARP1 protein CTD PMID:15461867 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Omeprazole affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Omeprazole affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein]
Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]
CTD PMID:19251492 PMID:26970604 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP Omeprazole affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Omeprazole affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Omeprazole affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Omeprazole affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression EXP Omeprazole affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Omeprazole affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Omeprazole affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Omeprazole affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Omeprazole affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Omeprazole affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
JBrowse link
G Pla2g4a phospholipase A2 group 4A increases phosphorylation
multiple interactions
ISO Omeprazole results in increased phosphorylation of PLA2G4A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]
CTD PMID:25797602 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Omeprazole affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488
JBrowse link
G Plg plasminogen affects expression EXP Omeprazole affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
JBrowse link
G Pls3 plastin 3 affects expression EXP Omeprazole affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:116,401,247...116,495,898
Ensembl chr  X:116,401,293...116,495,893
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Omeprazole affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996
JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO
EXP
Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein] CTD PMID:30452898 NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Omeprazole affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Omeprazole affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
JBrowse link
G Prl prolactin increases expression ISO Omeprazole results in increased expression of PRL protein CTD PMID:20726208 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Omeprazole affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Omeprazole affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Omeprazole affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Omeprazole affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Omeprazole affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Omeprazole affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Omeprazole affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Omeprazole affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Omeprazole affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 affects expression EXP Omeprazole affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
[Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein
Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]
CTD PMID:23038005 PMID:26970604 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptms parathymosin affects expression EXP Omeprazole affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Omeprazole affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Omeprazole affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Omeprazole affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Omeprazole affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]
Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]
CTD PMID:19251492 PMID:30452898 PMID:32418911 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Retsat retinol saturase increases expression EXP Omeprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Omeprazole affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Omeprazole affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Omeprazole affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:105,084,762...105,100,839
Ensembl chr 4:105,084,686...105,106,809
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Omeprazole affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Omeprazole affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Omeprazole affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Omeprazole affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Omeprazole affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638
Ensembl chr18:111,722,010...111,722,638
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Omeprazole affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Omeprazole affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Omeprazole affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:150,536,650...150,540,214
Ensembl chr 4:150,536,646...150,540,214
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Omeprazole affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
JBrowse link
G Rpn2 ribophorin II affects expression EXP Omeprazole affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:166,361,955...166,409,272
Ensembl chr 3:166,362,049...166,409,922
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Omeprazole affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Omeprazole affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Omeprazole affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Omeprazole affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621
Ensembl chr 9:42,839,965...43,095,621
Ensembl chr 5:42,839,965...43,095,621
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Omeprazole affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Omeprazole affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Omeprazole affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
JBrowse link
G Rras2 RAS related 2 affects expression EXP Omeprazole affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
JBrowse link
G RT1-DMa RT1 class II, locus DMa affects expression ISO Omeprazole affects the expression of HLA-DMA mRNA CTD PMID:25811541 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Omeprazole affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Omeprazole affects the expression of RT1-S3 mRNA CTD PMID:19483382 NCBI chr20:2,675,463...2,680,229 JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Omeprazole affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Omeprazole affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:8,186,004...8,216,576
Ensembl chr 5:8,185,985...8,218,898
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Omeprazole affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Omeprazole affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Omeprazole affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:59,841,090...59,850,641
Ensembl chr 8:59,841,090...59,850,641
JBrowse link
G Sell selectin L decreases expression EXP Omeprazole results in decreased expression of SELL protein CTD PMID:17652263 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Omeprazole affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Omeprazole affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
JBrowse link
G Serpina10 serpin family A member 10 affects expression EXP Omeprazole affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Omeprazole affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Omeprazole affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP Omeprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Omeprazole affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Omeprazole affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression EXP Omeprazole affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions EXP Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine] CTD PMID:19041296 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Omeprazole affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Omeprazole affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Omeprazole affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Omeprazole affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Omeprazole affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO Omeprazole results in decreased expression of SLC40A1 protein CTD PMID:31669099 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Omeprazole affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Omeprazole affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:75,976,000...76,014,651
Ensembl chr18:75,977,458...76,014,651
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Omeprazole affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 affects expression EXP Omeprazole affects the expression of SLCO1A1 mRNA CTD PMID:19483382 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO Omeprazole results in increased expression of SLCO1A2 mRNA CTD PMID:19118567 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein] CTD PMID:28849987 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Omeprazole affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:134,605,750...134,646,752
JBrowse link
G Srm spermidine synthase affects expression EXP Omeprazole affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Omeprazole affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:112,647,577...112,661,524 JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Omeprazole affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Omeprazole affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression EXP Omeprazole affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 4:106,866,329...106,895,686
Ensembl chr 4:106,866,114...106,895,689
JBrowse link
G Surf4 surfeit 4 affects expression EXP Omeprazole affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:30,646,435...30,659,641
Ensembl chr 3:30,638,299...30,661,390
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Omeprazole affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:106,920,970...106,966,543
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Omeprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Omeprazole affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Omeprazole affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Omeprazole affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:80,589,775...80,594,237
Ensembl chr18:80,589,783...80,594,237
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein] CTD PMID:16934674 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Omeprazole affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein] CTD PMID:32418911 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Omeprazole affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 affects expression EXP Omeprazole affects the expression of TEGT mRNA CTD PMID:19483382 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Omeprazole affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Omeprazole affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Omeprazole affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:41,505,167...41,512,243
Ensembl chr18:41,478,539...41,512,243
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Omeprazole affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Omeprazole affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818
JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression EXP Omeprazole results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:50,403,707...50,443,224
Ensembl chr11:50,398,349...50,443,114
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Omeprazole affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Omeprazole affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
JBrowse link
G Tyr tyrosinase multiple interactions
decreases expression
ISO Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole results in decreased expression of TYR protein
CTD PMID:25337692 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Omeprazole affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr16:18,952,583...18,954,780 JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Omeprazole affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:32,041,190...32,071,252 JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Omeprazole affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
affects expression
ISO
EXP
Omeprazole results in increased expression of UGT1A1 mRNA
Omeprazole affects the expression of UGT1A1 mRNA
CTD PMID:19118567 PMID:19483382 PMID:25626140 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 increases expression ISO Omeprazole results in increased expression of UGT1A5 mRNA CTD PMID:19118567 NCBI chr 9:96,228,134...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases expression ISO Omeprazole results in increased expression of UGT1A4 mRNA CTD PMID:19118567 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases expression
EXP
ISO
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
Omeprazole results in increased expression of UGT1A6 mRNA
CTD PMID:19118567 PMID:22687989 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO Omeprazole results in increased expression of UGT1A9 mRNA CTD PMID:19118567 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Omeprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Omeprazole affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,955,764...9,959,047
JBrowse link
G Vnn1 vanin 1 affects expression EXP Omeprazole affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Omeprazole affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:95,462,017...95,503,826
Ensembl chr13:95,462,020...95,503,738
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Omeprazole affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Omeprazole affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:70,224,581...70,240,971
Ensembl chr11:70,225,045...70,240,102
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Omeprazole affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
JBrowse link
albendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy7 adenylate cyclase 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ADCY7 mRNA CTD PMID:16861626 NCBI chr19:34,913,154...34,972,366
Ensembl chr19:34,914,322...34,936,743
JBrowse link
G Arl4c ARF like GTPase 4C multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of ARL4C mRNA CTD PMID:16861626 NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of BAG3 mRNA CTD PMID:16861626 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Albendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCL3 protein CTD PMID:16861626 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CCR7 mRNA CTD PMID:16861626 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCT3 mRNA CTD PMID:16861626 NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CTSL mRNA CTD PMID:16861626 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases activity
increases expression
ISO Albendazole results in increased activity of CYP1A1 promoter; Albendazole results in increased activity of CYP1A1 protein
Albendazole results in decreased activity of CYP1A1 protein
Albendazole results in increased expression of CYP1A1 mRNA
CTD PMID:12451431 PMID:16714371 PMID:18502397 PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
affects metabolic processing
ISO Albendazole results in increased expression of CYP1A2 mRNA
CYP1A2 protein affects the metabolism of Albendazole
CTD PMID:12451431 PMID:12920490 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Albendazole results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO
[SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole
[Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD PMID:19501153 PMID:22785256 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DNAJB1 mRNA CTD PMID:16861626 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DPYSL2 mRNA CTD PMID:16861626 NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of GEM mRNA CTD PMID:16861626 NCBI chr 5:30,011,641...30,022,554
Ensembl chr 5:30,011,592...30,022,542
JBrowse link
G Gpr183 G protein-coupled receptor 183 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of GPR183 mRNA CTD PMID:16861626 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Albendazole results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AA1 mRNA CTD PMID:16861626 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA CTD PMID:16861626 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA4 mRNA CTD PMID:16861626 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPD1 mRNA CTD PMID:16861626 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPE1 mRNA CTD PMID:16861626 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPH1 mRNA CTD PMID:16861626 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein CTD PMID:22785256 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL10 protein CTD PMID:16861626 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Albendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of MAP3K8 mRNA CTD PMID:16861626 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Albendazole results in decreased expression of MAPT mRNA; Albendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Albendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPID mRNA CTD PMID:16861626 NCBI chr 2:167,025,985...167,037,998
Ensembl chr 2:167,025,931...167,054,493
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPIF mRNA CTD PMID:16861626 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of PTGES3 mRNA CTD PMID:16861626 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Albendazole affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of SKAP2 mRNA CTD PMID:16861626 NCBI chr 4:82,281,221...82,431,664
Ensembl chr 4:82,263,709...82,432,886
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole CTD PMID:19501153 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA CTD PMID:16861626 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ST13 mRNA CTD PMID:16861626 NCBI chr 7:114,769,758...114,805,877
Ensembl chr 7:114,769,759...114,805,941
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of TCP1 mRNA CTD PMID:16861626 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TGIF1 mRNA CTD PMID:16861626 NCBI chr 9:118,194,735...118,204,354
Ensembl chr 9:118,194,444...118,204,442
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO U 0126 inhibits the reaction [Albendazole results in increased secretion of TNF protein] CTD PMID:20848085 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Albendazole affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TSC22D1 mRNA CTD PMID:16861626 NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Albendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
albendazole S-oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of albendazole sulfoxide CTD PMID:15703302 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO albendazole sulfoxide inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Tp53 tumor protein p53 affects activity ISO albendazole sulfoxide affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
astemizole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Astemizole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Astemizole results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Ak3 adenylate kinase 3 increases expression EXP Astemizole results in increased expression of AK3 mRNA CTD PMID:20221588 NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression EXP Astemizole results in increased expression of ALAS2 mRNA CTD PMID:20221588 NCBI chr  X:22,890,650...22,914,046
Ensembl chr  X:22,890,689...22,914,043
JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Astemizole results in increased expression of ANGPT2 mRNA CTD PMID:20221588 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Astemizole results in increased expression of ATF3 mRNA CTD PMID:32661532 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Astemizole results in increased expression of ATP1B1 mRNA CTD PMID:20221588 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Astemizole results in decreased expression of ATP1B2 mRNA CTD PMID:20221588 NCBI chr10:54,817,473...54,823,708
Ensembl chr10:54,817,476...54,823,708
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon increases expression EXP Astemizole results in increased expression of ATP5F1E mRNA CTD PMID:20221588 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Astemizole results in decreased expression of BCL2 mRNA CTD PMID:20221588 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression EXP Astemizole results in decreased expression of BMP1 mRNA CTD PMID:20221588 NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Astemizole results in decreased expression of CAMK2D mRNA CTD PMID:20221588 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276
JBrowse link
G Cat catalase increases expression EXP Astemizole results in increased expression of CAT mRNA CTD PMID:20221588 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression EXP Astemizole results in decreased expression of CCL7 mRNA CTD PMID:20221588 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Astemizole results in increased expression of CEBPB mRNA CTD PMID:20221588 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression EXP Astemizole results in decreased expression of CEBPG mRNA CTD PMID:20221588 NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:96,810,214...96,830,283
JBrowse link
G Cfh complement factor H decreases expression EXP Astemizole results in decreased expression of CFH mRNA CTD PMID:20221588 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression EXP Astemizole results in decreased expression of COLEC12 mRNA CTD PMID:20221588 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297
JBrowse link
G Cox6c-ps1 cytochrome c oxidase subunit VIc, pseudogene increases expression EXP Astemizole results in increased expression of COX6C-PS1 mRNA CTD PMID:20221588 NCBI chr19:69,090,047...69,090,905
Ensembl chr19:69,090,047...69,090,905
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] CTD PMID:18835572 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP Astemizole results in decreased expression of CXCL3 mRNA CTD PMID:20221588 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Astemizole results in decreased expression of CXCL9 mRNA CTD PMID:20221588 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 multiple interactions
increases metabolic processing
decreases methylation
ISO Arachidonic Acid inhibits the reaction [CYP2J2 protein results in decreased methylation of Astemizole]; ebastine inhibits the reaction [CYP2J2 protein results in decreased methylation of Astemizole]
CYP2J2 protein results in increased metabolism of Astemizole
CTD PMID:12386130 PMID:15861034 PMID:17162467 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases degradation ISO CYP3A4 protein results in increased degradation of Astemizole CTD PMID:15684493 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Eaf1 ELL associated factor 1 increases expression EXP Astemizole results in increased expression of EAF1 mRNA CTD PMID:20221588 NCBI chr16:6,704,727...6,719,476
Ensembl chr16:6,704,727...6,719,476
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression EXP Astemizole results in increased expression of EGLN1 mRNA CTD PMID:20221588 NCBI chr19:69,765,276...69,804,681 JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression EXP Astemizole results in increased expression of EIF4A1 mRNA CTD PMID:20221588 NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Astemizole results in decreased expression of ERRFI1 mRNA CTD PMID:20221588 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432
JBrowse link
G Etv5 ETS variant transcription factor 5 decreases expression EXP Astemizole results in decreased expression of ETV5 mRNA CTD PMID:20221588 NCBI chr11:92,113,171...92,170,758
Ensembl chr11:92,113,224...92,170,767
JBrowse link
G Fam124a family with sequence similarity 124 member A increases expression EXP Astemizole results in increased expression of FAM124A mRNA CTD PMID:20221588 NCBI chr15:40,975,789...41,031,069
Ensembl chr15:40,975,877...41,029,628
JBrowse link
G Fcer1a Fc epsilon receptor Ia multiple interactions EXP Astemizole inhibits the reaction [FCER1A protein results in increased secretion of HEXB protein] CTD PMID:9088877 NCBI chr13:88,218,427...88,224,723
Ensembl chr13:88,218,420...88,224,681
JBrowse link
G Gdf10 growth differentiation factor 10 increases expression EXP Astemizole results in increased expression of GDF10 mRNA CTD PMID:20221588 NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,243,317...9,256,794
JBrowse link
G Gimap1 GTPase, IMAP family member 1 increases expression EXP Astemizole results in increased expression of GIMAP1 mRNA CTD PMID:20221588 NCBI chr 4:79,018,473...79,022,360
Ensembl chr 4:79,018,202...79,022,525
JBrowse link
G Gpm6b glycoprotein m6b increases expression EXP Astemizole results in increased expression of GPM6B mRNA CTD PMID:20221588 NCBI chr  X:31,689,485...31,836,199
Ensembl chr  X:31,690,359...31,733,272
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP Astemizole results in increased expression of GPX4 mRNA CTD PMID:20221588 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions
EXP Astemizole results in increased secretion of HEXB protein
Astemizole inhibits the reaction [FCER1A protein results in increased secretion of HEXB protein]
CTD PMID:9088877 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Astemizole results in increased expression of HMOX1 mRNA CTD PMID:32661532 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO [Astemizole binds to and results in decreased activity of HRH1 protein] which affects the susceptibility to Aminophylline
Astemizole inhibits the reaction [Histamine results in decreased activity of [KCNQ2 protein co-treated with KCNQ3 protein co-treated with HRH1 protein]]
CTD PMID:12147327 PMID:16129921 NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Astemizole results in decreased expression of HSP90AB1 mRNA CTD PMID:20221588 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Astemizole results in increased expression of HSPA8 mRNA CTD PMID:20221588 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression EXP Astemizole results in increased expression of HSPB8 mRNA CTD PMID:20221588 NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression EXP Astemizole results in decreased expression of HSPH1 mRNA CTD PMID:20221588 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Astemizole inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein] CTD PMID:17517105 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression EXP Astemizole results in decreased expression of IFIT3 mRNA CTD PMID:20221588 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Astemizole inhibits the reaction [IGF1 protein results in increased activity of KCNH1 protein] CTD PMID:17520698 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 decreases expression EXP Astemizole results in decreased expression of IGSF6 mRNA CTD PMID:20221588 NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Astemizole inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; Astemizole inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein] CTD PMID:17517105 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression EXP Astemizole results in increased expression of IL36RN mRNA CTD PMID:20221588 NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:27,442,709...27,449,306
JBrowse link
G Il7r interleukin 7 receptor decreases expression EXP Astemizole results in decreased expression of IL7R mRNA CTD PMID:20221588 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027
JBrowse link
G Itga8 integrin subunit alpha 8 increases expression EXP Astemizole results in increased expression of ITGA8 mRNA CTD PMID:20221588 NCBI chr17:80,213,139...80,410,633
Ensembl chr17:80,213,143...80,410,633
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 multiple interactions
decreases activity
affects binding
ISO Astemizole binds to and results in decreased activity of KCNH1 protein; Astemizole inhibits the reaction [IGF1 protein results in increased activity of KCNH1 protein]
Astemizole results in decreased activity of KCNH1 protein
Astemizole binds to KCNH1 protein
CTD PMID:14985237 PMID:16816845 PMID:17520698 PMID:18471075 PMID:18497958 More... NCBI chr13:106,253,101...106,555,712
Ensembl chr13:106,253,213...106,555,710
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
affects binding
decreases activity
affects localization
ISO
EXP
Astemizole binds to and results in decreased activity of KCNH2 protein; Astemizole inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]; Astemizole inhibits the reaction [Digoxin results in decreased activity of KCNH2 protein]; Astemizole inhibits the reaction [Digoxin results in decreased metabolism of KCNH2 protein modified form]; Astemizole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; dofetilide analog inhibits the reaction [Astemizole binds to KCNH2 protein]; Hydrogen Peroxide inhibits the reaction [Astemizole results in decreased activity of KCNH2 protein mutant form]; Potassium promotes the reaction [Astemizole binds to KCNH2 protein]
Astemizole binds to KCNH2 gene polymorphism; Astemizole binds to KCNH2 protein
Astemizole affects the localization of KCNH2 protein mutant form
CTD PMID:8641472 PMID:9658196 PMID:10376921 PMID:10422790 PMID:10531299 More... NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 multiple interactions ISO Astemizole inhibits the reaction [Histamine results in decreased activity of [KCNQ2 protein co-treated with KCNQ3 protein co-treated with HRH1 protein]] CTD PMID:12147327 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 multiple interactions ISO Astemizole inhibits the reaction [Histamine results in decreased activity of [KCNQ2 protein co-treated with KCNQ3 protein co-treated with HRH1 protein]] CTD PMID:12147327 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610
JBrowse link
G Maoa monoamine oxidase A decreases expression EXP Astemizole results in decreased expression of MAOA mRNA CTD PMID:20221588 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631
JBrowse link
G Mapt microtubule-associated protein tau affects binding ISO Astemizole binds to MAPT protein alternative form CTD PMID:20110603 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP Astemizole results in decreased expression of MMP2 mRNA CTD PMID:20221588 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A decreases expression EXP Astemizole results in decreased expression of MS4A6A mRNA CTD PMID:20221588 NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013
JBrowse link
G Mt2 metallothionein 2 increases expression ISO Astemizole results in increased expression of MT2A mRNA CTD PMID:32661532 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [Astemizole results in increased expression of MT1M mRNA] CTD PMID:32661532 NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression EXP Astemizole results in decreased expression of MTUS1 mRNA CTD PMID:20221588 NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474
JBrowse link
G Myh6 myosin heavy chain 6 increases expression EXP Astemizole results in increased expression of MYH6 mRNA CTD PMID:20221588 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 increases expression EXP Astemizole results in increased expression of NDUFS7 mRNA CTD PMID:20221588 NCBI chr 7:10,103,226...10,110,862
Ensembl chr 7:10,103,227...10,110,691
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP Astemizole results in increased expression of NDUFV2 mRNA CTD PMID:20221588 NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 decreases expression EXP Astemizole results in decreased expression of NECAB1 mRNA CTD PMID:20221588 NCBI chr 5:33,155,078...33,375,707
Ensembl chr 5:33,153,975...33,375,707
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Astemizole results in increased expression of NR4A3 mRNA CTD PMID:20221588 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression EXP Astemizole results in decreased expression of OASL1 mRNA CTD PMID:20221588 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 increases expression EXP Astemizole results in increased expression of OSBPL3 mRNA CTD PMID:20221588 NCBI chr 4:80,677,383...80,854,169
Ensembl chr 4:80,677,390...80,854,169
JBrowse link
G Osgepl1 O-sialoglycoprotein endopeptidase-like 1 increases expression EXP Astemizole results in increased expression of OSGEPL1 mRNA CTD PMID:20221588 NCBI chr 9:55,707,389...55,725,325
Ensembl chr 9:55,707,392...55,721,346
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression EXP Astemizole results in increased expression of PARK7 mRNA CTD PMID:20221588 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825
JBrowse link
G Pcdh17 protocadherin 17 decreases expression EXP Astemizole results in decreased expression of PCDH17 mRNA CTD PMID:20221588 NCBI chr15:66,631,549...66,725,007
Ensembl chr15:66,633,142...66,722,105
JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 increases expression EXP Astemizole results in increased expression of PELI2 mRNA CTD PMID:20221588 NCBI chr15:23,872,984...24,017,448
Ensembl chr15:23,872,984...24,014,817
JBrowse link
G Prl8a3 prolactin family 8, subfamily A, member 3 decreases expression EXP Astemizole results in decreased expression of PRL8A3 mRNA CTD PMID:20221588 NCBI chr17:37,716,716...37,723,215 JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP Astemizole results in increased expression of PSMB5 mRNA CTD PMID:20221588 NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Astemizole results in decreased expression of PTGS1 mRNA CTD PMID:20221588 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 increases expression EXP Astemizole results in increased expression of PYCR3 mRNA CTD PMID:20221588 NCBI chr 7:109,484,263...109,489,554 JBrowse link
G Pygm glycogen phosphorylase, muscle associated increases expression EXP Astemizole results in increased expression of PYGM mRNA CTD PMID:20221588 NCBI chr 1:213,119,805...213,134,622
Ensembl chr 1:213,119,791...213,134,612
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Astemizole results in increased expression of S100A8 mRNA CTD PMID:20221588 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221
JBrowse link
G S100b S100 calcium binding protein B decreases expression EXP Astemizole results in decreased expression of S100B mRNA CTD PMID:20221588 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Astemizole results in decreased expression of SIK1 mRNA CTD PMID:20221588 NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698
JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression EXP Astemizole results in increased expression of SLC1A1 mRNA CTD PMID:20221588 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP Astemizole results in increased expression of SOD2 mRNA CTD PMID:20221588 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP Astemizole results in increased expression of SQSTM1 mRNA CTD PMID:20221588 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
JBrowse link
G Tf transferrin decreases expression EXP Astemizole results in decreased expression of TF mRNA CTD PMID:20221588 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Astemizole results in increased expression of TGFB2 mRNA CTD PMID:20221588 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression EXP Astemizole results in decreased expression of TLR2 mRNA CTD PMID:20221588 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
JBrowse link
G Tlr7 toll-like receptor 7 decreases expression EXP Astemizole results in decreased expression of TLR7 mRNA CTD PMID:20221588 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:30,644,355...30,672,151
JBrowse link
G Tmod1 tropomodulin 1 increases expression EXP Astemizole results in increased expression of TMOD1 mRNA CTD PMID:20221588 NCBI chr 5:65,112,062...65,189,563
Ensembl chr 5:65,134,132...65,189,561
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Astemizole inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein] CTD PMID:17517105 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Vcan versican decreases expression EXP Astemizole results in decreased expression of VCAN mRNA CTD PMID:20221588 NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955
JBrowse link
azilsartan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of BAX protein CTD PMID:29408668 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in decreased expression of BCL2L1 protein CTD PMID:29408668 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of CASP9 protein CTD PMID:29408668 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
benomyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam33 ADAM metallopeptidase domain 33 multiple interactions
increases expression
ISO ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein] CTD PMID:27784618 NCBI chr 3:138,715,428...138,736,392
Ensembl chr 3:138,724,046...138,736,347
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Benomyl results in decreased expression of AKT1 mRNA CTD PMID:33930522 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity ISO
EXP
Benomyl metabolite results in decreased activity of ALDH2 protein; Benomyl results in decreased activity of ALDH2 protein CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:15331769 PMID:17010440 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity EXP Benomyl results in decreased activity of ALDH5A1 protein CTD PMID:17010440 NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,558,347...40,586,714
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression EXP Benomyl results in decreased expression of AMPD3 mRNA CTD PMID:15885261 NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608
JBrowse link
G Ar androgen receptor multiple interactions ISO Benomyl inhibits the reaction [Dihydrotestosterone affects the localization of and results in increased phosphorylation of AR protein] CTD PMID:25324206 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein] CTD PMID:16903866 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases phosphorylation
ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein]
Benomyl results in increased phosphorylation of BCL2 protein
CTD PMID:16903866 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Benomyl results in increased expression of BUB1B protein CTD PMID:16903866 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Benomyl results in increased expression of CA2 mRNA CTD PMID:15885261 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression
multiple interactions
ISO Benomyl results in increased expression of CCL17 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]
CTD PMID:27784618 NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895
JBrowse link
G Ccnb1 cyclin B1 increases response to substance ISO CCNB1 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnb2 cyclin B2 increases response to substance ISO CCNB2 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
JBrowse link
G Cd38 CD38 molecule decreases expression EXP Benomyl results in decreased expression of CD38 mRNA CTD PMID:15885261 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO Benomyl results in decreased expression of CYP17A1 mRNA
Benomyl results in decreased expression of and results in decreased activity of CYP17A1 protein
CTD PMID:25324206 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO Benomyl results in increased activity of CYP19A1 protein
Benomyl results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 PMID:25543211 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of DDIT3 protein] CTD PMID:27784618 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO Benomyl results in increased expression of EIF2AK3 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]
CTD PMID:27784618 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ERN1 protein] CTD PMID:27784618 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO Benomyl binds to and results in increased activity of ESR1 protein; Benomyl inhibits the reaction [Estradiol binds to ESR1 protein]
Benomyl binds to ESR1 protein
CTD PMID:14579009 PMID:16626760 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression EXP Benomyl results in increased expression of FGFR4 mRNA CTD PMID:15885261 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 increases expression EXP Benomyl results in increased expression of GIPC1 mRNA CTD PMID:15885261 NCBI chr19:41,380,125...41,392,078
Ensembl chr19:41,380,125...41,391,725
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP Benomyl results in increased expression of GLYAT mRNA CTD PMID:15885261 NCBI chr 1:219,128,798...219,149,615
Ensembl chr 1:219,128,811...219,150,774
JBrowse link
G Hdac1 histone deacetylase 1 decreases activity ISO Benomyl results in decreased activity of HDAC1 protein CTD PMID:25543211 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO Benomyl results in increased expression of HSPA5 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]
CTD PMID:27784618 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Benomyl results in increased expression of HSPB1 mRNA CTD PMID:15885261 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO Benomyl results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Benomyl results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO Benomyl inhibits the reaction [Dihydrotestosterone results in increased secretion of KLK3 protein] CTD PMID:25324206 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
JBrowse link
G Klk1c8 kallikrein 1-related peptidase C8 decreases expression EXP Benomyl results in decreased expression of KLK1B21 mRNA CTD PMID:15885261 NCBI chr 1:103,684,293...103,688,155
Ensembl chr 1:103,684,293...103,688,155
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP Benomyl results in increased expression of MAPK8 mRNA CTD PMID:33930522 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mir21 microRNA 21 decreases expression EXP Benomyl results in decreased expression of MIR21 mRNA CTD PMID:33930522 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
increases expression
ISO Benomyl results in decreased expression of MMP2 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]
CTD PMID:25530041 PMID:27784618 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP
ISO
Benomyl results in decreased expression of MMP9 protein
Benomyl results in decreased expression of MMP9 mRNA
CTD PMID:10026946 PMID:25530041 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mmrn1 multimerin 1 increases expression EXP Benomyl results in increased expression of MMRN1 mRNA CTD PMID:15885261 NCBI chr 4:91,205,462...91,280,862
Ensembl chr 4:91,233,240...91,280,861
JBrowse link
G Msmb microseminoprotein, beta increases expression EXP Benomyl results in increased expression of MSMB mRNA CTD PMID:15885261 NCBI chr16:7,372,803...7,393,406
Ensembl chr16:7,372,819...7,393,405
JBrowse link
G Mt2 metallothionein 2 increases expression EXP Benomyl results in increased expression of MT2A mRNA CTD PMID:15885261 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Benomyl inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Or10al27 olfactory receptor family 10 subfamily AL member 27 increases expression EXP Benomyl results in increased expression of OR10AL27 mRNA CTD PMID:15885261 NCBI chr20:794,490...795,491
Ensembl chr20:743,522...816,076
JBrowse link
G Or13p4 olfactory receptor family 13 subfamily P member 4 increases expression EXP Benomyl results in increased expression of OR13P4 mRNA CTD PMID:15885261 NCBI chr 5:137,502,182...137,503,129
Ensembl chr 5:137,502,182...137,503,129
JBrowse link
G Or9s23b olfactory receptor family 9 subfamily S member 23B increases expression EXP Benomyl results in increased expression of OR9S23B mRNA CTD PMID:15885261 NCBI chr 9:100,564,786...100,565,757
Ensembl chr 9:100,564,786...100,565,757
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CXCL8 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA] CTD PMID:27784618 NCBI chr10:84,086,317...84,092,673
Ensembl chr10:84,086,317...84,093,548
JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO Benomyl results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Benomyl results in increased cleavage of PARP1 protein CTD PMID:16903866 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Benomyl results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
JBrowse link
G Pten phosphatase and tensin homolog increases expression EXP Benomyl results in increased expression of PTEN mRNA CTD PMID:33930522 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Benomyl results in increased expression of RELA mRNA CTD PMID:33930522 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Benomyl results in decreased expression of SCD1 mRNA CTD PMID:15885261 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO Benomyl results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
JBrowse link
G Sh2d4a SH2 domain containing 4A increases expression EXP Benomyl results in increased expression of SH2D4A mRNA CTD PMID:15885261 NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Benomyl results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Benomyl results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Tnf tumor necrosis factor decreases expression EXP Benomyl results in decreased expression of TNF mRNA CTD PMID:33930522 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Benomyl affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
ISO Benomyl results in increased expression of TSLP mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA]
CTD PMID:27784618 NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO Benomyl results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:4,062,216...4,084,192
Ensembl chr  X:4,062,182...4,084,246
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions EXP Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]; Benomyl inhibits the reaction [Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein] CTD PMID:15331769 NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:88,038,037...88,058,650
JBrowse link
binimetinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [NADP co-treated with binimetinib] results in decreased activity of CYP1A2 protein CTD PMID:33728909 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
candesartan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme affects expression EXP candesartan affects the expression of ACE mRNA CTD PMID:18796534 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP candesartan results in decreased expression of ACE2 mRNA CTD PMID:18796534 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
decreases expression
ISO [candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; candesartan promotes the reaction [Ramipril results in increased expression of ADIPOQ]; Ramipril promotes the reaction [candesartan results in increased expression of ADIPOQ]
candesartan results in increased expression of ADIPOQ; candesartan results in increased expression of ADIPOQ protein
candesartan results in decreased expression of ADIPOQ
CTD PMID:16443859 PMID:17483542 PMID:19059660 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Agt angiotensinogen multiple interactions ISO
EXP
candesartan inhibits the reaction [[AGT co-treated with REN] results in increased abundance of Aldosterone]; candesartan inhibits the reaction [AGT protein results in increased chemical synthesis of Nitric Oxide]; candesartan inhibits the reaction [AGT protein results in increased chemical synthesis of Reactive Oxygen Species]
candesartan inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]]; candesartan inhibits the reaction [AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; candesartan inhibits the reaction [AGT protein results in increased expression of ENG mRNA]; candesartan inhibits the reaction [AGT protein results in increased expression of ENG protein]; candesartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; candesartan inhibits the reaction [AGT protein results in increased expression of PTHLH mRNA]; candesartan inhibits the reaction [AGT protein results in increased expression of PTHLH protein]; candesartan inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; candesartan inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]
candesartan inhibits the reaction [AGT protein modified form results in increased expression of COL1A2 protein]; candesartan inhibits the reaction [AGT results in increased expression of NOS3 protein]; candesartan inhibits the reaction [AGT results in increased expression of PTGS2 protein]; candesartan inhibits the reaction [AGT results in increased expression of VEGFA protein]
CTD PMID:10525314 PMID:11729239 PMID:12065685 PMID:15539634 PMID:15728788 More... NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
decreases expression
ISO
EXP
candesartan binds to and results in decreased activity of AGTR1 protein
candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]
candesartan results in decreased expression of AGTR1A mRNA
CTD PMID:15728788 PMID:18796534 PMID:21474964 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
decreases expression
ISO
EXP
[PD 123319 binds to and results in decreased activity of AGTR2 protein] inhibits the reaction [candesartan results in increased expression of NOS3 protein]
candesartan results in decreased expression of AGTR2 mRNA
CTD PMID:18551021 PMID:18796534 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745
JBrowse link
G Akap11 A-kinase anchoring protein 11 increases expression EXP candesartan results in increased expression of AKAP11 mRNA CTD PMID:14871019 NCBI chr15:60,320,839...60,365,480
Ensembl chr15:60,320,839...60,365,335
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases expression EXP candesartan results in decreased expression of AKR1B1 mRNA CTD PMID:14871019 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP candesartan results in decreased phosphorylation of AKT1 protein CTD PMID:17922026 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Atg5 autophagy related 5 multiple interactions EXP candesartan inhibits the reaction [Galactose results in decreased expression of ATG5 mRNA] CTD PMID:34906534 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions EXP candesartan inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 protein] CTD PMID:16723803 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP candesartan results in increased expression of BAX mRNA; candesartan results in increased expression of BAX protein CTD PMID:11409658 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bdkrb2 bradykinin receptor B2 decreases expression EXP candesartan results in decreased expression of BDKRB2 mRNA CTD PMID:18796534 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209
JBrowse link
G Becn1 beclin 1 multiple interactions EXP candesartan inhibits the reaction [Galactose results in decreased expression of BECN1 mRNA] CTD PMID:34906534 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G Ca1 carbonic anhydrase 1 decreases activity ISO candesartan results in decreased activity of CA1 protein CTD PMID:11196069 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased expression of CASP3 protein]; candesartan inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]]; candesartan inhibits the reaction [Gentamicins results in increased expression of CASP3 protein] CTD PMID:23300732 PMID:30368989 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP candesartan inhibits the reaction [Galactose results in decreased activity of CAT protein] CTD PMID:34906534 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP candesartan results in decreased expression of CCN2 mRNA CTD PMID:16685210 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression
increases expression
ISO
EXP
T 0070907 inhibits the reaction [candesartan results in increased expression of CD36 mRNA]
candesartan results in decreased expression of CD36 mRNA
CTD PMID:14871019 PMID:22124178 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases expression
ISO candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] CTD PMID:16443859 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO candesartan inhibits the reaction [AGT protein modified form results in increased expression of COL1A2 protein] CTD PMID:11729239 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression EXP candesartan results in decreased expression of CRISPLD2 mRNA CTD PMID:14871019 NCBI chr19:64,961,764...65,020,099
Ensembl chr19:64,961,771...65,020,349
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] CTD PMID:14620923 PMID:16443859 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP candesartan inhibits the reaction [Indomethacin results in increased expression of CXCL1 protein] CTD PMID:17763956 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression
multiple interactions
ISO
EXP
candesartan results in decreased expression of CYBA protein
candesartan results in decreased expression of CYBA; candesartan results in decreased expression of CYBA mRNA
Amlodipine promotes the reaction [candesartan results in decreased expression of CYBA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of CYBA]
CTD PMID:16139267 PMID:16685210 PMID:18551021 PMID:21107329 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
EXP Amlodipine promotes the reaction [candesartan results in decreased expression of CYBB]; Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of CYBB]
candesartan results in decreased expression of CYBB; candesartan results in decreased expression of CYBB mRNA
CTD PMID:16685210 PMID:21107329 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 affects response to substance
decreases expression
ISO
EXP
CYP11B2 protein polymorphism affects the susceptibility to candesartan
candesartan results in decreased expression of CYP11B2 mRNA
CTD PMID:12065207 PMID:18796534 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921
JBrowse link
G Eng endoglin multiple interactions EXP candesartan inhibits the reaction [AGT protein results in increased expression of ENG mRNA]; candesartan inhibits the reaction [AGT protein results in increased expression of ENG protein] CTD PMID:15539634 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933
JBrowse link
G Faslg Fas ligand multiple interactions EXP candesartan inhibits the reaction [Daunorubicin results in increased expression of FASLG protein] CTD PMID:16324756 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP candesartan inhibits the reaction [[Acetaldehyde co-treated with Cyanamide] results in increased expression of FOS protein]; candesartan inhibits the reaction [Acetaldehyde promotes the reaction [Cyanamide results in increased expression of FOS protein]] CTD PMID:26298003 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein] CTD PMID:21255808 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
JBrowse link
G Gcg glucagon multiple interactions ISO [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein] CTD PMID:21255808 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:67,522,489...67,531,533
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP candesartan inhibits the reaction [Galactose results in decreased expression of GDNF mRNA] CTD PMID:34906534 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression EXP candesartan results in decreased expression of HSPE1 mRNA CTD PMID:14871019 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] CTD PMID:16139267 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression EXP candesartan results in decreased expression of ID1 mRNA CTD PMID:14871019 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased expression of IL1B protein]; candesartan inhibits the reaction [Gentamicins results in increased expression of IL1B protein] CTD PMID:30368989 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions EXP candesartan inhibits the reaction [AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; candesartan inhibits the reaction [AGT protein results in increased expression of IL6 protein] CTD PMID:10525314 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein] CTD PMID:21255808 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 decreases expression ISO candesartan decreases expression of KCNN4 mRNA and protein in CD4-positive, alpha-beta T cell RGD PMID:29388859 RGD:329955575 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275
JBrowse link
G Klk1 kallikrein 1 decreases expression EXP candesartan results in decreased expression of KLK1 mRNA CTD PMID:18796534 NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270
JBrowse link
G Lep leptin multiple interactions
increases response to substance
decreases expression
ISO
EXP
candesartan promotes the reaction [Ramipril results in increased expression of LEP]; Ramipril promotes the reaction [candesartan results in increased expression of LEP]
LEP protein results in increased susceptibility to candesartan
candesartan results in decreased expression of LEP
CTD PMID:17483542 PMID:19059660 PMID:21287150 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP candesartan inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23300732 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP candesartan inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23300732 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP candesartan results in increased expression of MMP13 protein CTD PMID:19047581 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression EXP candesartan results in increased expression of MMP15 mRNA CTD PMID:19047581 NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,669,506...9,691,000
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP candesartan results in decreased expression of MMP9 mRNA; candesartan results in decreased expression of MMP9 protein CTD PMID:19047581 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP candesartan inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17763956 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP candesartan inhibits the reaction [Streptozocin results in increased expression of NOS2 protein] CTD PMID:16139267 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO
EXP
[PD 123319 binds to and results in decreased activity of AGTR2 protein] inhibits the reaction [candesartan results in increased expression of NOS3 protein]
candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]
candesartan inhibits the reaction [AGT results in increased expression of NOS3 protein]
CTD PMID:12065685 PMID:16139267 PMID:18551021 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions
decreases expression
EXP Amlodipine promotes the reaction [candesartan results in decreased expression of NOX1]; Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of NOX1] CTD PMID:21107329 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression
multiple interactions
ISO
EXP
candesartan results in decreased expression of NOX4 protein
Amlodipine promotes the reaction [candesartan results in decreased expression of NOX4]; Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of NOX4]
CTD PMID:18551021 PMID:21107329 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
JBrowse link
G Nppa natriuretic peptide A increases expression
increases secretion
EXP candesartan results in increased expression of NPPA mRNA; candesartan results in increased expression of NPPA protein
candesartan results in increased secretion of NPPA protein
CTD PMID:14639023 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 affects expression EXP candesartan affects the expression of NR3C2 mRNA CTD PMID:18796534 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
JBrowse link
G Or4b1d olfactory receptor family 4 subfamily B member 1D increases expression EXP candesartan results in increased expression of OR4B1D mRNA CTD PMID:14871019 NCBI chr 3:96,663,710...96,664,636
Ensembl chr 3:96,663,710...96,664,636
JBrowse link
G Pln phospholamban multiple interactions EXP candesartan inhibits the reaction [Isoproterenol results in decreased phosphorylation of PLN protein] CTD PMID:16723803 NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241
JBrowse link
G Pmch pro-melanin-concentrating hormone decreases expression EXP candesartan results in decreased expression of PMCH mRNA CTD PMID:21287150 NCBI chr 7:24,399,404...24,400,720
Ensembl chr 7:24,399,404...24,400,720
JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression EXP candesartan results in decreased expression of PTGIS mRNA CTD PMID:14871019 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO candesartan inhibits the reaction [AGT results in increased expression of PTGS2 protein] CTD PMID:12065685 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pthlh parathyroid hormone-like hormone multiple interactions EXP candesartan inhibits the reaction [AGT protein results in increased expression of PTHLH mRNA]; candesartan inhibits the reaction [AGT protein results in increased expression of PTHLH protein] CTD PMID:15728788 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased phosphorylation of RELA protein]; candesartan inhibits the reaction [Gentamicins results in increased phosphorylation of RELA protein] CTD PMID:30368989 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Ren renin multiple interactions
increases expression
decreases activity
ISO
EXP
candesartan inhibits the reaction [[AGT co-treated with REN] results in increased abundance of Aldosterone]
candesartan results in increased expression of REN mRNA
candesartan results in decreased activity of REN protein
CTD PMID:18679781 PMID:18796534 PMID:19047581 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions EXP candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein] CTD PMID:16723803 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705
JBrowse link
G Slc22a25 solute carrier family 22, member 25 multiple interactions ISO candesartan inhibits the reaction [SLC22A9 protein results in increased uptake of estrone sulfate] CTD PMID:17132213 NCBI chr 1:214,767,837...214,956,535
Ensembl chr 1:214,767,837...214,862,340
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP [benazepril co-treated with candesartan] results in decreased expression of SMAD3 protein CTD PMID:19487956 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [benazepril co-treated with candesartan] results in decreased expression of TGFB1 protein; candesartan inhibits the reaction [Nitric Oxide deficiency results in increased expression of TGFB1 mRNA] CTD PMID:16778335 PMID:19487956 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Thbd thrombomodulin multiple interactions EXP candesartan inhibits the reaction [Nitric Oxide deficiency results in decreased expression of THBD protein] CTD PMID:16778335 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression EXP candesartan results in decreased expression of TIMP2 mRNA CTD PMID:19047581 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression EXP candesartan results in decreased expression of TIMP3 mRNA CTD PMID:19047581 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
candesartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; candesartan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; T 0070907 inhibits the reaction [candesartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]
candesartan results in decreased expression of TNF mRNA
[candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased expression of TNF protein]; candesartan inhibits the reaction [Galactose results in increased expression of TNF mRNA]; candesartan inhibits the reaction [Gentamicins results in increased expression of TNF protein]
CTD PMID:22124178 PMID:30368989 PMID:34906534 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 increases expression EXP candesartan results in increased expression of TP53 mRNA; candesartan results in increased expression of TP53 protein CTD PMID:11409658 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression
multiple interactions
EXP
ISO
candesartan results in decreased expression of UCP2 mRNA
candesartan inhibits the reaction [Palmitic Acid results in increased expression of UCP2 mRNA]
CTD PMID:16685210 PMID:20667613 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP candesartan inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein] CTD PMID:16139267 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
ISO candesartan results in decreased expression of VEGFA
candesartan inhibits the reaction [VEGFA protein results in increased expression of VEGFA mRNA]
candesartan inhibits the reaction [AGT results in increased expression of VEGFA protein]
CTD PMID:12065685 PMID:16202860 PMID:16675585 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression EXP candesartan results in decreased expression of YBX3 mRNA CTD PMID:14871019 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691
JBrowse link
carbendazim term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 increases expression EXP carbendazim results in increased expression of ABI2 mRNA CTD PMID:22952946 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO carbendazim results in increased expression of ACACA mRNA CTD PMID:26071454 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP [carbendazim co-treated with mancozeb] results in increased activity of ACHE protein CTD PMID:33217513 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of AGPAT2 mRNA CTD PMID:26071454 NCBI chr 3:29,814,924...29,826,569
Ensembl chr 3:29,814,924...29,826,581
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization
ISO AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]
carbendazim affects the localization of AHR protein
CTD PMID:27286660 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Alb albumin decreases expression EXP carbendazim results in decreased expression of ALB protein CTD PMID:35437878 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Anxa10 annexin A10 increases expression ISO carbendazim results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961
JBrowse link
G Arg1 arginase 1 decreases expression ISO carbendazim results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP carbendazim results in increased expression of BAG1 mRNA CTD PMID:22952946 NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP carbendazim results in increased expression of BAX mRNA; carbendazim results in increased expression of BAX protein CTD PMID:35437878 PMID:35513110 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP carbendazim results in decreased expression of BCL2 mRNA CTD PMID:35437878 PMID:35513110 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l14 Bcl2-like 14 increases expression EXP carbendazim results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases activity ISO carbendazim results in increased activity of BUB1B protein CTD PMID:37506866 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression
ISO
EXP
carbendazim results in increased activity of CASP3 protein
Chitosan inhibits the reaction [carbendazim results in increased expression of CASP3 protein]
CTD PMID:30851412 PMID:35705592 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase decreases activity
decreases expression
multiple interactions
EXP carbendazim results in decreased activity of CAT protein
carbendazim results in decreased expression of CAT protein
[Chlorpyrifos co-treated with carbendazim] results in decreased activity of CAT protein; Chitosan inhibits the reaction [carbendazim results in decreased expression of CAT protein]
CTD PMID:27268782 PMID:35513110 PMID:35705592 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO carbendazim results in increased expression of CCNB1 protein CTD PMID:37506866 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Clca2 chloride channel accessory 2 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129
JBrowse link
G Cldn11 claudin 11 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein CTD PMID:28576679 NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539
JBrowse link
G Clu clusterin decreases expression
increases expression
EXP carbendazim results in decreased expression of CLU mRNA
carbendazim results in increased expression of CLU mRNA
CTD PMID:22952946 PMID:27466211 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO carbendazim results in increased activity of CYP19A1 protein
carbendazim results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
carbendazim results in increased expression of CYP1A1 mRNA; carbendazim results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]; salicylamide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]
CTD PMID:10103034 PMID:21784029 PMID:27286660 PMID:32194361 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO carbendazim results in increased expression of CYP1A2 mRNA; carbendazim results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO carbendazim results in increased expression of CYP2B6 mRNA CTD PMID:22310298 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO carbendazim results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO carbendazim results in decreased activity of CYP2D6 protein CTD PMID:20183062 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO carbendazim results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO carbendazim results in decreased expression of CYP7A1 mRNA; carbendazim results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO carbendazim results in increased expression of DGAT1 mRNA CTD PMID:26071454 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of DGAT2 mRNA CTD PMID:26071454 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 decreases expression EXP carbendazim results in decreased expression of DNAAF11 mRNA CTD PMID:27466211 NCBI chr 7:100,033,843...100,134,979
Ensembl chr 7:100,034,202...100,135,179
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 3:28,563,240...28,567,492
Ensembl chr 3:28,563,240...28,567,492
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
affects localization
EXP
ISO
carbendazim results in decreased expression of ESR1 mRNA
carbendazim affects the localization of ESR1 protein
CTD PMID:28576679 PMID:37506866 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP carbendazim results in decreased expression of ESR2 mRNA CTD PMID:28576679 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fabp9 fatty acid binding protein 9 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 protein]
carbendazim results in decreased expression of FABP9 mRNA; carbendazim results in decreased expression of FABP9 protein
CTD PMID:33965443 NCBI chr 2:93,499,136...93,503,267
Ensembl chr 2:93,499,134...93,503,260
JBrowse link
G Fank1 fibronectin type III and ankyrin repeat domains 1 increases expression EXP carbendazim results in increased expression of FANK1 mRNA CTD PMID:22952946 NCBI chr 1:198,007,496...198,114,790
Ensembl chr 1:198,007,547...198,115,561
JBrowse link
G Foxa2 forkhead box A2 increases expression ISO carbendazim results in increased expression of FOXA2 mRNA CTD PMID:26071454 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions
EXP carbendazim results in decreased expression of FSHB protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of FSHB protein]
CTD PMID:33965443 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO carbendazim results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP carbendazim results in increased expression of GFAP protein CTD PMID:35513110 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein CTD PMID:28576679 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases secretion
multiple interactions
EXP carbendazim results in increased secretion of GOT1 protein
Chitosan inhibits the reaction [carbendazim results in increased secretion of GOT1 protein]
CTD PMID:35705592 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
increases secretion
multiple interactions
EXP carbendazim results in increased expression of GPT protein
carbendazim results in increased secretion of GPT protein
Chitosan inhibits the reaction [carbendazim results in increased secretion of GPT protein]
CTD PMID:35437878 PMID:35705592 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
EXP Chitosan inhibits the reaction [carbendazim results in decreased expression of HMOX1 mRNA] CTD PMID:35705592 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Ift81 intraflagellar transport 81 decreases expression EXP carbendazim results in decreased expression of IFT81 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr12:39,618,559...39,697,971
Ensembl chr12:39,618,651...39,697,962
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [carbendazim results in decreased expression of IL10 protein] CTD PMID:33965443 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta increases expression ISO
EXP
carbendazim results in increased expression of IL1B mRNA; carbendazim results in increased expression of IL1B protein CTD PMID:26071454 PMID:35513110 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
carbendazim results in increased expression of IL6 mRNA; carbendazim results in increased expression of IL6 protein
Carnitine inhibits the reaction [carbendazim results in increased expression of IL6 protein]
CTD PMID:26071454 PMID:33965443 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO carbendazim results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO carbendazim results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
EXP Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
multiple interactions
EXP carbendazim results in decreased expression of LHB protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of LHB protein]
CTD PMID:33965443 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
JBrowse link
G Loxl1 lysyl oxidase-like 1 multiple interactions
increases expression
EXP 2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA CTD PMID:22382377 NCBI chr 8:67,587,636...67,612,224
Ensembl chr 8:67,587,636...67,612,224
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO carbendazim results in decreased expression of LPL protein CTD PMID:30496565 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA CTD PMID:22382377 NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects localization ISO carbendazim affects the localization of MAPK1 protein modified form CTD PMID:37506866 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects localization ISO carbendazim affects the localization of MAPK3 protein modified form CTD PMID:37506866 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP carbendazim results in increased expression of MAPK8 mRNA CTD PMID:35513110 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP carbendazim results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr16:34,422,490...34,465,544
Ensembl chr16:34,426,696...34,441,709
JBrowse link
G Mir128-1 microRNA 128-1 increases expression EXP carbendazim results in increased expression of MIR128-1 mRNA CTD PMID:32418910 NCBI chr13:42,251,884...42,251,965
Ensembl chr13:42,251,884...42,251,965
JBrowse link
G Mir423 microRNA 423 increases expression EXP carbendazim results in increased expression of MIR423 mRNA CTD PMID:32418910 NCBI chr10:62,412,272...62,412,350 JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO carbendazim results in decreased expression of MMP2 mRNA CTD PMID:25530041 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO carbendazim results in decreased expression of MMP9 mRNA CTD PMID:25530041 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP [Chlorpyrifos co-treated with carbendazim] results in increased activity of MPO protein
carbendazim results in increased activity of MPO protein
CTD PMID:27268782 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
decreases expression
ISO
EXP
carbendazim results in increased expression of NFE2L2 protein
Chitosan inhibits the reaction [carbendazim results in decreased expression of NFE2L2 mRNA]
CTD PMID:30851412 PMID:35705592 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Carnitine inhibits the reaction [carbendazim results in increased expression of NOS2 protein]; Chitosan inhibits the reaction [carbendazim results in increased expression of NOS2 protein] CTD PMID:33965443 PMID:35705592 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO carbendazim inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Ocln occludin decreases expression
multiple interactions
EXP carbendazim results in decreased expression of OCLN protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of OCLN protein]
CTD PMID:33965443 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression EXP carbendazim results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO carbendazim results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression EXP carbendazim results in decreased expression of PTGDS mRNA CTD PMID:22952946 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO carbendazim results in increased expression of PTTG1 protein CTD PMID:37506866 NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP carbendazim results in increased expression of RELA protein
Carnitine inhibits the reaction [carbendazim results in increased expression of RELA protein]
CTD PMID:33965443 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO carbendazim results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:122,448,323...122,510,410
JBrowse link
G Sil1 SIL1 nucleotide exchange factor decreases expression EXP carbendazim results in decreased expression of SIL1 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr18:27,146,526...27,378,459
Ensembl chr18:27,146,527...27,307,693
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP carbendazim results in increased expression of SOD3 mRNA CTD PMID:27466211 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO carbendazim results in increased expression of SREBF1 mRNA CTD PMID:26071454 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
EXP carbendazim results in decreased expression of STAR mRNA; carbendazim results in decreased expression of STAR protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR protein]
CTD PMID:33965443 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases expression EXP carbendazim results in decreased expression of TBC1D5 mRNA CTD PMID:27466211 NCBI chr 9:3,740,032...4,256,971
Ensembl chr 9:3,750,325...4,253,581
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO carbendazim results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO carbendazim results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Carnitine inhibits the reaction [carbendazim results in increased expression of TNF protein] CTD PMID:33965443 PMID:35437878 PMID:35513110 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnp1 transition protein 1 increases expression EXP carbendazim results in increased expression of TNP1 mRNA CTD PMID:28576679 NCBI chr 9:82,043,669...82,044,278
Ensembl chr 9:82,043,672...82,044,278
JBrowse link
G Tnp2 transition protein 2 increases expression EXP carbendazim results in increased expression of TNP2 mRNA CTD PMID:28576679 NCBI chr10:5,386,735...5,387,463
Ensembl chr10:5,383,885...5,387,467
JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
EXP
ISO
carbendazim results in increased expression of TP53 mRNA
carbendazim affects the activity of TP53 protein
CTD PMID:35435491 PMID:35513110 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP carbendazim results in increased expression of TSHB protein CTD PMID:33965443 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984
JBrowse link
CGP 12177 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions
affects binding
increases activity
ISO
EXP
[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP; [CGP 12177 binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP; Alprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [CGP 12177 results in increased activity of ADRB1 protein]; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Carvedilol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Carvedilol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; CGP 12177 binds to and results in decreased activity of ADRB1 protein; CGP 12177 inhibits the reaction [cyanopindolol binds to ADRB1 protein]; CGP 12177 inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 20712A inhibits the reaction [[CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [CGP 12177 results in increased activity of ADRB1 protein]; Metoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Nadolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Nebivolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Oxprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Pindolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [CGP 12177 results in increased activity of ADRB1 protein]; Sotalol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Timolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
Atenolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; carvedilol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; CGP 20712A inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Labetalol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Nebivolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Pindolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Propranolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]
CTD PMID:2462161 PMID:9593075 PMID:10217540 PMID:12535855 PMID:12761341 More... NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
affects binding
ISO
EXP
[CGP 12177 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; carvedilol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; CGP 12177 binds to and results in decreased activity of ADRB2 protein; CGP 12177 inhibits the reaction [cyanopindolol binds to ADRB2 protein]; N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide inhibits the reaction [CGP 12177 binds to ADRB2 protein]
Atenolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; carvedilol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; ICI 118551 inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Labetalol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Pindolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Propranolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]
CTD PMID:2462161 PMID:9593075 PMID:12535855 PMID:14730417 PMID:17628611 More... NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
affects binding
increases activity
affects response to substance
ISO
EXP
[CGP 12177 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; CGP 12177 binds to and results in increased activity of ADRB3 protein; CGP 12177 inhibits the reaction [cyanopindolol binds to ADRB3 protein]; N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide inhibits the reaction [CGP 12177 binds to ADRB3 protein]
CGP 12177 results in increased activity of ADRB3 protein
ADRB3 affects the susceptibility to CGP 12177
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [CGP 12177 results in increased activity of ADRB3 protein]; CGP 12177 binds to and results in increased activity of ADRB3 protein
CTD PMID:7815362 PMID:8569714 PMID:10217540 PMID:10952688 PMID:11159692 More... NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]; Pertussis Toxin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]; U 0126 inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]; wortmannin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein] CTD PMID:15563584 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein promotes the reaction [CGP 12177 results in increased metabolism of Lipids] CTD PMID:14981226 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
JBrowse link
G Lpl lipoprotein lipase increases expression EXP CGP 12177 results in increased expression of LPL mRNA CTD PMID:9032464 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity ISO CGP 12177 results in increased activity of MAPK1 protein CTD PMID:15563584 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity ISO CGP 12177 results in increased activity of MAPK3 protein CTD PMID:15563584 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Usf1 upstream transcription factor 1 multiple interactions ISO USF1 gene polymorphism promotes the reaction [CGP 12177 results in increased metabolism of Lipids]; USF1 protein affects the reaction [CGP 12177 results in increased metabolism of Lipids] CTD PMID:15985485 NCBI chr13:86,377,679...86,385,523
Ensembl chr13:86,377,717...86,385,522
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO CGP 12177 results in increased expression of VEGFA mRNA CTD PMID:10788502 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
chlormidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO chlormidazole inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO chlormidazole inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; chlormidazole inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO chlormidazole results in decreased expression of IDH3A mRNA CTD PMID:30818834 NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO chlormidazole results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO chlormidazole results in increased activity of NR1I3 protein CTD PMID:30818834 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO chlormidazole inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
ciclobendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO ciclobendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
clemizole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP [clemizole co-treated with Cisplatin] results in decreased expression of CAT protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of CAT protein] CTD PMID:37102204 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions
ISO clemizole results in increased expression of CYP2B6 mRNA
[clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA
CTD PMID:31312845 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO clemizole results in increased expression of CYP3A4 mRNA
[clemizole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:31312845 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 increases expression ISO clemizole results in increased expression of G6PC1 mRNA CTD PMID:31312845 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [clemizole co-treated with Cisplatin] results in increased expression of LCN2 protein; clemizole inhibits the reaction [Cisplatin results in increased expression of LCN2 protein] CTD PMID:37102204 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO clemizole promotes the reaction [MED1 protein binds to NR1I3 protein alternative form] CTD PMID:31312845 NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO clemizole promotes the reaction [NCOA3 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP [Cisplatin co-treated with clemizole] results in decreased expression of NPHS1 protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of NPHS1 protein] CTD PMID:37102204 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [clemizole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:31312845 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
affects binding
multiple interactions
ISO clemizole affects the localization of NR1I3 protein mutant form
clemizole binds to NR1I3 protein
[clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; clemizole binds to and results in increased activity of NR1I3 protein alternative form; clemizole inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; clemizole promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein]; clemizole promotes the reaction [NCOA3 protein binds to NR1I3 protein]
CTD PMID:31312845 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO clemizole results in increased expression of PCK1 mRNA CTD PMID:31312845 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP clemizole inhibits the reaction [Cisplatin results in increased expression of RAC1 protein] CTD PMID:37102204 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO clemizole results in decreased expression of SCD mRNA CTD PMID:31312845 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
JBrowse link
G Synpo synaptopodin multiple interactions EXP [Cisplatin co-treated with clemizole] results in decreased expression of SYNPO protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of SYNPO protein] CTD PMID:37102204 NCBI chr18:56,326,369...56,347,359
Ensembl chr18:56,319,571...56,353,306
JBrowse link
G Thrsp thyroid hormone responsive affects expression ISO clemizole affects the expression of THRSP mRNA CTD PMID:31312845 NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827
JBrowse link
dabigatran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 decreases expression ISO Dabigatran results in decreased expression of AIF1 protein CTD PMID:27397090 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Dabigatran results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Dabigatran results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614
JBrowse link
G F2 coagulation factor II, thrombin decreases activity ISO Dabigatran results in decreased activity of F2 protein CTD PMID:17911567 PMID:25138021 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO Dabigatran inhibits the reaction [Dietary Fats results in increased cleavage of [FGA protein binds to FGB protein binds to FGG protein]] CTD PMID:25138021 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577
JBrowse link
G Fgb fibrinogen beta chain multiple interactions ISO Dabigatran inhibits the reaction [Dietary Fats results in increased cleavage of [FGA protein binds to FGB protein binds to FGG protein]] CTD PMID:25138021 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Dabigatran results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions ISO Dabigatran inhibits the reaction [Dietary Fats results in increased cleavage of [FGA protein binds to FGB protein binds to FGG protein]] CTD PMID:25138021 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Dabigatran results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of GDNF mRNA] CTD PMID:28585189 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Dabigatran results in decreased expression of GFAP protein CTD PMID:27397090 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Hoxb9 homeo box B9 increases expression ISO Dabigatran results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Dabigatran results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase increases expression ISO Dabigatran results in increased expression of MERTK mRNA CTD PMID:27397090 NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Dabigatran results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:218,767,205...218,769,772
Ensembl chr 2:218,765,949...218,769,784
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of NR4A2 mRNA] CTD PMID:28585189 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Dabigatran results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:15,900,881...15,902,953
Ensembl chr 1:15,900,736...15,902,274
JBrowse link
G Pax3 paired box 3 decreases expression ISO Dabigatran results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141
JBrowse link
G Pax6 paired box 6 increases expression ISO Dabigatran results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
JBrowse link
G Plp1 proteolipid protein 1 increases expression ISO Dabigatran results in increased expression of PLP1 mRNA CTD PMID:27397090 NCBI chr  X:104,933,921...104,993,317
Ensembl chr  X:104,975,780...104,993,314
JBrowse link
G Rcor2 REST corepressor 2 multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of RCOR2 mRNA] CTD PMID:28585189 NCBI chr 1:213,882,585...213,890,022
Ensembl chr 1:213,878,519...213,890,022
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of RET protein] CTD PMID:28585189 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of SLC18A2 mRNA] CTD PMID:28585189 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231
JBrowse link
G Snca synuclein alpha multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in increased expression of SNCA mRNA] CTD PMID:28585189 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Dabigatran results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:161,099,301...161,105,083
Ensembl chr 3:161,099,301...161,105,083
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in decreased expression of TH mRNA] CTD PMID:28585189 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Dabigatran inhibits the reaction [Rotenone results in increased expression of TNF mRNA] CTD PMID:28585189 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Uncx UNC homeobox decreases expression ISO Dabigatran results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:20,206,604...20,211,125
Ensembl chr12:20,206,609...20,211,125
JBrowse link
danuglipron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glp1r glucagon-like peptide 1 receptor increases activity
multiple interactions
ISO danuglipron results in increased activity of GLP1R protein
[danuglipron results in increased activity of GLP1R protein] which results in increased abundance of Cyclic AMP
CTD PMID:39395609 NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,973,352...9,011,654
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 increases activity ISO danuglipron results in increased activity of KCNH2 protein CTD PMID:39395609 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
desmethylastemizole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh1 potassium voltage-gated channel subfamily H member 1 decreases activity ISO desmethylastemizole results in decreased activity of KCNH1 protein CTD PMID:16816845 NCBI chr13:106,253,101...106,555,712
Ensembl chr13:106,253,213...106,555,710
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO desmethylastemizole binds to and results in decreased activity of KCNH2 protein CTD PMID:10376921 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
domperidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance ISO ABCB1 gene SNP affects the susceptibility to Domperidone CTD PMID:21063774 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Adra1d adrenoceptor alpha 1D affects response to substance ISO ADRA1D gene SNP affects the susceptibility to Domperidone CTD PMID:21063774 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Domperidone inhibits the reaction [Indomethacin results in increased expression of CXCL2 mRNA] CTD PMID:21691039 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Domperidone inhibits the reaction [Indomethacin results in increased expression of CXCL1 mRNA] CTD PMID:21691039 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Domperidone results in increased expression of CYP1A1 mRNA CTD PMID:9860486 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation ISO CYP1A2 protein results in increased hydroxylation of Domperidone CTD PMID:15327587 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases hydroxylation ISO CYP2B6 protein results in increased hydroxylation of Domperidone CTD PMID:15327587 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases hydroxylation ISO CYP2C8 protein results in increased hydroxylation of Domperidone CTD PMID:15327587
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation ISO CYP2D6 protein results in increased hydroxylation of Domperidone CTD PMID:15327587 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein results in increased hydroxylation of and results in decreased alkylation of Domperidone CTD PMID:15327587 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
affects binding
ISO Cyclosporine promotes the reaction [Domperidone binds to DRD1 protein] CTD PMID:12673668 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding
ISO
EXP
Cyclosporine promotes the reaction [Domperidone binds to DRD2 protein]
Domperidone binds to and results in decreased activity of DRD2 protein
CTD PMID:2571179 PMID:8103596 PMID:10626749 PMID:12071432 PMID:12130853 More... NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339
JBrowse link
G Il6 interleukin 6 decreases expression ISO Domperidone results in decreased expression of IL6 protein CTD PMID:10568223 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
affects response to substance
ISO Domperidone results in decreased activity of KCNH2 protein
Domperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
KCNH2 gene SNP affects the susceptibility to Domperidone
CTD PMID:15640612 PMID:19583963 PMID:21063774 PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Domperidone inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:21691039 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Domperidone inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:21691039 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Prl prolactin multiple interactions
increases expression
ISO
EXP
Domperidone inhibits the reaction [Deoxyepinephrine results in decreased expression of PRL protein]; Domperidone inhibits the reaction [Dopamine results in decreased expression of PRL protein]
Domperidone results in increased expression of PRL protein
CTD PMID:1304515 PMID:1874184 PMID:6736848 PMID:8532072 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Domperidone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Domperidone results in decreased expression of TGFB1 protein CTD PMID:10568223 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Domperidone binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
JBrowse link
droperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
ISO Droperidol results in decreased activity of KCNH2 protein
Droperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
CTD PMID:16757186 PMID:21158687 PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Droperidol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
emedastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO emedastine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
esomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Mycophenolic Acid promotes the reaction [Esomeprazole results in increased expression of CYP1A1 mRNA] CTD PMID:25929522 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
fenbendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Fenbendazole analog results in decreased expression of ARAF protein CTD PMID:35569513 NCBI chr  X:3,780,932...3,845,919
Ensembl chr  X:3,780,932...3,792,611
JBrowse link
G Aurkb aurora kinase B increases expression EXP Fenbendazole results in increased expression of AURKB protein CTD PMID:23411599 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Fenbendazole analog results in increased expression of BAX protein; Fenbendazole results in increased expression of BAX protein
Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased expression of BAX protein]; SB 203580 inhibits the reaction [Fenbendazole analog results in increased expression of BAX protein]; SB 203580 inhibits the reaction [Fenbendazole results in increased expression of BAX protein]
CTD PMID:35569513 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Fenbendazole analog results in decreased expression of BCL2 protein; Fenbendazole results in decreased expression of BCL2 protein CTD PMID:35569513 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
ISO Fenbendazole analog results in increased expression of CASP3 mRNA
Fenbendazole analog results in increased cleavage of CASP3 protein; Fenbendazole results in increased cleavage of CASP3 protein
CTD PMID:35569513 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases expression ISO Fenbendazole analog results in increased expression of CASP8 mRNA; Fenbendazole results in increased expression of CASP8 mRNA CTD PMID:35569513 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases cleavage
increases expression
ISO Fenbendazole analog results in increased cleavage of CASP9 protein; Fenbendazole results in increased cleavage of CASP9 protein
Fenbendazole analog results in increased expression of CASP9 mRNA; Fenbendazole results in increased expression of CASP9 mRNA
CTD PMID:35569513 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cbx5 chromobox 5 increases expression EXP Fenbendazole results in increased expression of CBX5 protein CTD PMID:23411599 NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Fenbendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Fenbendazole results in increased expression of CCND1 mRNA CTD PMID:23411599 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccne2 cyclin E2 increases expression EXP Fenbendazole results in increased expression of CCNE2 mRNA CTD PMID:23411599 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Fenbendazole analog results in increased expression of CDH1 protein; Fenbendazole results in increased expression of CDH1 protein CTD PMID:35569513 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cdh2 cadherin 2 affects expression ISO Fenbendazole affects the expression of CDH2 protein; Fenbendazole analog affects the expression of CDH2 protein CTD PMID:35569513 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Fenbendazole results in increased expression of CDK1 mRNA; Fenbendazole results in increased expression of CDK1 protein CTD PMID:23411599 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Fenbendazole results in increased expression of CDKN1A mRNA; Fenbendazole results in increased expression of CDKN1A protein CTD PMID:23411599 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases methylation
increases expression
decreases expression
EXP Fenbendazole results in increased methylation of CDKN2A gene
Fenbendazole results in increased expression of CDKN2A protein
Fenbendazole results in decreased expression of CDKN2A protein
CTD PMID:22659510 PMID:23411599 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP Fenbendazole results in increased expression of CDKN2B mRNA CTD PMID:23411599 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression EXP Fenbendazole results in increased expression of CDR2 mRNA CTD PMID:23411599 NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Fenbendazole results in decreased activity of CYP1A2 protein CTD PMID:22048645 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Fenbendazole analog results in increased expression of DNM1L mRNA; Fenbendazole results in increased expression of DNM1L mRNA CTD PMID:35569513 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Fenbendazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Fenbendazole analog results in increased expression of H2AX protein; Fenbendazole results in increased expression of H2AX protein CTD PMID:35569513 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Fenbendazole results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
JBrowse link
G Ifng interferon gamma increases expression ISO Fenbendazole analog results in increased expression of IFNG mRNA; Fenbendazole results in increased expression of IFNG mRNA CTD PMID:35569513 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il6 interleukin 6 increases expression ISO Fenbendazole analog results in increased expression of IL6 mRNA; Fenbendazole results in increased expression of IL6 mRNA CTD PMID:35569513 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Fenbendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Incenp inner centromere protein increases expression EXP Fenbendazole results in increased expression of INCENP protein CTD PMID:23411599 NCBI chr 1:215,945,558...216,017,247
Ensembl chr 1:215,948,283...215,977,084
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Fenbendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO Fenbendazole analog results in increased expression of MDH2 mRNA; Fenbendazole results in increased expression of MDH2 mRNA CTD PMID:35569513 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:26,530,881...26,543,841
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Fenbendazole results in increased expression of MDM2 mRNA CTD PMID:23411599 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO Fenbendazole results in increased expression of MFN2 mRNA CTD PMID:35569513 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Fenbendazole results in increased expression of MKI67 protein CTD PMID:23411599 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Fenbendazole analog results in decreased expression of MMP2 mRNA; Fenbendazole analog results in decreased expression of MMP2 protein CTD PMID:35569513 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects expression
decreases expression
ISO Fenbendazole affects the expression of MMP9 protein; Fenbendazole analog affects the expression of MMP9 protein
Fenbendazole analog results in decreased expression of MMP9 mRNA; Fenbendazole results in decreased expression of MMP9 mRNA
CTD PMID:35569513 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Fenbendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression ISO Fenbendazole results in increased expression of OPA1 mRNA CTD PMID:35569513 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Fenbendazole results in decreased expression of PTGS2 mRNA CTD PMID:35569513 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
ISO Fenbendazole analog results in increased phosphorylation of RELA protein; Fenbendazole results in increased phosphorylation of RELA protein
Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased phosphorylation of RELA protein]
CTD PMID:35569513 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO Fenbendazole analog results in increased expression of SIRT1 mRNA; Fenbendazole results in increased expression of SIRT1 mRNA CTD PMID:35569513 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Fenbendazole analog results in decreased expression of SLC2A1 mRNA; Fenbendazole results in decreased expression of SLC2A1 mRNA CTD PMID:35569513 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO Fenbendazole analog results in decreased expression of SLC2A4 mRNA; Fenbendazole results in decreased expression of SLC2A4 mRNA CTD PMID:35569513 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha increases expression ISO Fenbendazole analog results in increased expression of SUCLG1 mRNA; Fenbendazole results in increased expression of SUCLG1 mRNA CTD PMID:35569513 NCBI chr 4:106,866,329...106,895,686
Ensembl chr 4:106,866,114...106,895,689
JBrowse link
G Tmem70 transmembrane protein 70 multiple interactions EXP [Diethylnitrosamine co-treated with Fenbendazole] results in decreased expression of TMEM70 protein CTD PMID:27914986 NCBI chr 5:7,420,396...7,438,023
Ensembl chr 5:7,420,396...7,438,023
JBrowse link
G Tnf tumor necrosis factor increases secretion
increases expression
multiple interactions
ISO Fenbendazole results in increased secretion of TNF protein
Fenbendazole analog results in increased expression of TNF mRNA
U 0126 inhibits the reaction [Fenbendazole results in increased secretion of TNF protein]
CTD PMID:20848085 PMID:35569513 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 increases expression EXP
ISO
Fenbendazole results in increased expression of TP53 protein
Fenbendazole analog results in increased expression of TP53 protein; Fenbendazole results in increased expression of TP53 protein
CTD PMID:23411599 PMID:35569513 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 multiple interactions EXP [Diethylnitrosamine co-treated with Fenbendazole] results in decreased expression of UBE2E2 protein CTD PMID:27914986 NCBI chr15:9,411,067...9,688,731
Ensembl chr15:9,411,539...9,712,661
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Fenbendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression EXP Fenbendazole results in decreased expression of WEE1 protein modified form CTD PMID:23411599 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449
JBrowse link
flubendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO flubendazole results in decreased expression of ARHGEF2 protein CTD PMID:30075109 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation ISO flubendazole results in increased phosphorylation of BCL2 protein CTD PMID:32652169 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 increases phosphorylation ISO flubendazole results in increased phosphorylation of BCL2L1 protein CTD PMID:32652169 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO flubendazole results in increased cleavage of CASP3 protein
BAY 11-7085 affects the reaction [flubendazole results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; Cyclosporine inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]
CTD PMID:32652169 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein] CTD PMID:30075109 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO flubendazole results in increased activity of MAPK8 protein CTD PMID:32652169 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases phosphorylation ISO flubendazole results in increased phosphorylation of MCL1 protein CTD PMID:32652169 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO flubendazole results in increased expression of PMAIP1 protein CTD PMID:32652169 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO flubendazole results in decreased expression of PTK2 protein CTD PMID:30075109 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO flubendazole results in decreased expression of RAC1 protein CTD PMID:30075109 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions
ISO flubendazole results in increased activity of RELA protein
4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine affects the reaction [flubendazole results in increased activity of RELA protein]; BAY 11-7085 affects the reaction [flubendazole results in increased activity of RELA protein]
CTD PMID:32652169 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO flubendazole results in decreased expression of RHOA protein CTD PMID:30075109 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tp53 tumor protein p53 increases activity ISO flubendazole results in increased activity of TP53 protein CTD PMID:32652169 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
lansoprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Lansoprazole results in increased expression of ABCA1 protein
Lansoprazole results in increased expression of ABCA1 mRNA; Lansoprazole results in increased expression of ABCA1 protein
CTD PMID:20060385 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance ISO ABCB1 affects the susceptibility to Lansoprazole CTD PMID:19238367 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Apoe apolipoprotein E increases expression ISO Lansoprazole results in increased expression of APOE mRNA; Lansoprazole results in increased expression of APOE protein CTD PMID:20060385 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
JBrowse link
G Aqp4 aquaporin 4 increases expression ISO Lansoprazole results in increased expression of AQP4 mRNA; Lansoprazole results in increased expression of AQP4 protein CTD PMID:20437101 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in decreased expression of BCL2 mRNA] CTD PMID:28412091 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G C1qa complement C1q A chain decreases expression EXP Lansoprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Lansoprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP Lansoprazole results in decreased expression of C4BPA mRNA CTD PMID:25626140 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Lansoprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
Lansoprazole inhibits the reaction [Demecolcine results in increased activity of CASP3 protein]
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of CASP3 mRNA]; Lansoprazole inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
CTD PMID:12530016 PMID:28412091 PMID:29339218 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Lansoprazole inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:18726076 PMID:29339218 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cfi complement factor I decreases expression EXP Lansoprazole results in decreased expression of CFI mRNA CTD PMID:25626140 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression
multiple interactions
EXP Lansoprazole results in decreased expression of CXCL1 mRNA; Lansoprazole results in decreased expression of CXCL1 protein
Lansoprazole inhibits the reaction [Indomethacin results in increased expression of CXCL1 mRNA]; Lansoprazole inhibits the reaction [Indomethacin results in increased expression of CXCL1 protein]
CTD PMID:15334676 PMID:16328016 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases activity
increases expression
ISO
EXP
Lansoprazole results in increased activity of CYP1A1 promoter
Lansoprazole results in decreased activity of CYP1A1 protein
Lansoprazole results in increased expression of CYP1A1 mRNA; Lansoprazole results in increased expression of CYP1A1 protein
CTD PMID:8169844 PMID:8647108 PMID:8900397 PMID:9041675 PMID:9152597 More... NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO
EXP
Lansoprazole results in increased expression of CYP1A2 mRNA; Lansoprazole results in increased expression of CYP1A2 protein CTD PMID:8169844 PMID:9152597 PMID:9744552 PMID:12623754 PMID:14550749 More... NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
decreases activity
ISO Lansoprazole results in increased expression of CYP1B1 mRNA
Lansoprazole results in decreased activity of CYP1B1 protein
CTD PMID:12623754 PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Lansoprazole results in increased expression of CYP2B1 protein CTD PMID:9152597 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Lansoprazole results in increased expression of CYP2B2 protein CTD PMID:9152597 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases hydroxylation ISO CYP2C18 protein results in increased hydroxylation of Lansoprazole CTD PMID:7870052 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects response to substance
increases expression
decreases activity
increases hydroxylation
affects metabolic processing
increases metabolic processing
decreases metabolic processing
multiple interactions
ISO
EXP
CYP2C19 gene affects the susceptibility to Lansoprazole; CYP2C19 gene polymorphism affects the susceptibility to Lansoprazole
Lansoprazole results in increased expression of CYP2C6 mRNA; Lansoprazole results in increased expression of CYP2C6 protein
Lansoprazole results in decreased activity of CYP2C19 protein
CYP2C19 protein results in increased hydroxylation of Lansoprazole
CYP2C19 protein affects the metabolism of Lansoprazole
CYP2C19 protein results in increased metabolism of Lansoprazole; Lansoprazole results in increased metabolism of CYP2C19 protein
CYP2C19 gene polymorphism results in decreased metabolism of Lansoprazole
CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus]; Famotidine inhibits the reaction [CYP2C19 gene affects the susceptibility to Lansoprazole]; Lansoprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]
CTD PMID:8627562 PMID:8930576 PMID:9152597 PMID:9272410 PMID:11829200 More... NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects metabolic processing
increases hydroxylation
ISO CYP2C8 protein affects the metabolism of Lansoprazole
CYP2C8 protein results in increased hydroxylation of Lansoprazole
CTD PMID:7870052 PMID:8627562
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases degradation
multiple interactions
ISO Lansoprazole results in decreased degradation of CYP2E1 protein
Lansoprazole results in increased expression of and results in increased activity of CYP2E1 protein
CTD PMID:36243147 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
increases hydroxylation
increases expression
affects metabolic processing
ISO CYP3A4 protein results in increased metabolism of Lansoprazole
CYP3A4 protein results in increased hydroxylation of Lansoprazole
Lansoprazole results in increased expression of CYP3A4 mRNA; Lansoprazole results in increased expression of CYP3A4 protein
CYP3A4 protein affects the metabolism of Lansoprazole
CTD PMID:7870052 PMID:8627562 PMID:8930576 PMID:9744552 PMID:10859152 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole] CTD PMID:17377957 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Lansoprazole results in increased expression of CYP4A1 protein CTD PMID:9152597 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Lansoprazole results in increased expression of EGFR protein CTD PMID:9881512 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in increased expression of FAS protein] CTD PMID:29339218 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Faslg Fas ligand multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in increased expression of FASLG protein] CTD PMID:29339218 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Lansoprazole results in decreased expression of FGF2 protein CTD PMID:9881512 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Lansoprazole results in increased expression of FGF21 protein CTD PMID:8774986 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056
JBrowse link
G Gast gastrin increases expression ISO
EXP
Lansoprazole results in increased expression of GAST protein CTD PMID:7750667 PMID:8792694 PMID:11680587 PMID:11975934 PMID:12189558 More... NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Lansoprazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO Lansoprazole results in increased expression of HAMP mRNA CTD PMID:31669099 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
increases activity
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lansoprazole results in increased expression of HMOX1 mRNA]; Lansoprazole results in increased activity of and results in increased expression of HMOX1 protein
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA affects the reaction [Lansoprazole results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA affects the reaction [Lansoprazole results in increased expression of HMOX1 protein]; U 0126 inhibits the reaction [Lansoprazole results in increased expression of HMOX1 protein]
Lansoprazole results in increased expression of HMOX1 mRNA; Lansoprazole results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lansoprazole results in increased activity of HMOX1 promoter]
CTD PMID:16712795 PMID:19628634 PMID:19764090 PMID:28412091 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
ISO Lansoprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
Lansoprazole results in decreased expression of IFNG mRNA
CTD PMID:16932910 PMID:19232345 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:29339218 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
Lansoprazole results in decreased expression of IL1B mRNA
Lansoprazole inhibits the reaction [Ethanol results in increased expression of IL1B protein]
CTD PMID:16932910 PMID:29339218 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
ISO
EXP
Lansoprazole results in decreased expression of IL6 mRNA
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 mRNA]
CTD PMID:16932910 PMID:28412091 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases oxidation EXP Lansoprazole results in increased oxidation of KEAP1 protein CTD PMID:19628634 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression
EXP Lansoprazole inhibits the reaction [LHB protein results in increased abundance of Testosterone]
Lansoprazole results in increased expression of LHB protein
CTD PMID:7589908 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP Lansoprazole results in increased phosphorylation of MAPK1 protein CTD PMID:19628634 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP Lansoprazole results in increased phosphorylation of MAPK3 protein CTD PMID:19628634 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapt microtubule-associated protein tau affects binding ISO Lansoprazole binds to MAPT protein alternative form CTD PMID:20110603 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Lansoprazole inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; Lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 PMID:17895592 PMID:18726076 PMID:24337826 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
increases phosphorylation
EXP Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of NFE2L2 mRNA]; NFE2L2 mRNA affects the reaction [Lansoprazole results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA affects the reaction [Lansoprazole results in increased expression of HMOX1 protein]
Lansoprazole results in increased expression of NFE2L2 mRNA
Lansoprazole results in increased phosphorylation of NFE2L2 protein
CTD PMID:19628634 PMID:28412091 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in decreased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:29339218 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases activity ISO Lansoprazole results in increased activity of NR1H2 protein CTD PMID:20060385 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases activity ISO Lansoprazole results in increased activity of NR1H3 protein CTD PMID:20060385 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Lansoprazole results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases activity ISO Lansoprazole results in decreased activity of PHOSPHO1 protein CTD PMID:17227223 NCBI chr10:81,258,810...81,266,345
Ensembl chr10:81,257,427...81,268,481
JBrowse link
G Pomc proopiomelanocortin increases expression ISO Lansoprazole results in increased expression of POMC protein CTD PMID:16524691 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP AG-041R inhibits the reaction [Lansoprazole results in increased expression of PTGS2 protein] CTD PMID:12438555 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Lansoprazole inhibits the reaction [Ethanol results in decreased expression of and results in increased phosphorylation of RELA protein] CTD PMID:29339218 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Retsat retinol saturase decreases expression EXP Lansoprazole results in decreased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP Lansoprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
JBrowse link
G Shh sonic hedgehog signaling molecule decreases expression ISO Lansoprazole results in decreased expression of SHH mRNA CTD PMID:20437101 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Lansoprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO [Lansoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Lansoprazole results in increased expression of TGFA protein CTD PMID:9881512 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Lansoprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Lansoprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]
Lansoprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
Lansoprazole results in decreased expression of TNF mRNA
CTD PMID:16932910 PMID:19232345 PMID:29339218 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA] CTD PMID:28412091 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Lansoprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Lansoprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
ledipasvir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects binding ISO ledipasvir binds to ABCG2 protein CTD PMID:33954893 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Klrc1 killer cell lectin like receptor C1 decreases expression ISO ledipasvir co-treated with sofosbuvir decreases expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr 4:164,828,163...164,838,446
Ensembl chr 4:164,828,163...164,838,464
JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 affects expression ISO ledipasvir co-treated sofosbuvir with affects expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr 1:78,657,409...78,665,255
Ensembl chr 1:78,659,262...78,703,273
JBrowse link
liarozole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO liarozole results in decreased activity of CYP26A1 protein
[liarozole co-treated with Tretinoin] results in increased expression of CYP26A1 mRNA; liarozole promotes the reaction [Tretinoin results in increased expression of CYP26A1 mRNA]
CTD PMID:15597402 PMID:16279770 PMID:21428449 PMID:21838328 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
JBrowse link
mebendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Mebendazole results in decreased expression of ABCB1 mRNA; Mebendazole results in decreased expression of ABCB1 protein CTD PMID:28606429 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression ISO Mebendazole results in decreased expression of ABCC1 mRNA CTD PMID:28606429 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression ISO Mebendazole results in increased expression of AGER mRNA CTD PMID:24747151 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Mebendazole results in decreased expression of ARHGEF2 protein CTD PMID:30075109 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Mebendazole results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein] CTD PMID:18667591 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects response to substance
multiple interactions
increases phosphorylation
ISO BCL2 protein affects the susceptibility to Mebendazole
[Mebendazole results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein]
CTD PMID:18667591 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Mebendazole results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261
JBrowse link
G Casp3 caspase 3 increases activity ISO Mebendazole results in increased activity of CASP3 protein CTD PMID:37473966 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp7 caspase 7 increases activity ISO Mebendazole results in increased activity of CASP7 protein CTD PMID:37473966 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Mebendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein] CTD PMID:30075109 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO
EXP
Mebendazole results in increased expression of CYP1A1 mRNA; Mebendazole results in increased expression of CYP1A1 protein CTD PMID:9860486 PMID:12841937 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO
EXP
Mebendazole results in increased expression of CYP1A2 protein CTD PMID:12841937 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Ereg epiregulin increases expression ISO Mebendazole results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Mebendazole results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
affects binding
ISO Mebendazole results in decreased expression of GAPDH mRNA
Mebendazole binds to GAPDH protein
CTD PMID:37473966 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Mebendazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Mebendazole results in decreased expression of HES1 protein CTD PMID:32277947 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
JBrowse link
G Hk1 hexokinase 1 affects binding
decreases expression
ISO Mebendazole binds to HK1 protein
Mebendazole results in decreased expression of HK1 mRNA
CTD PMID:37473966 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Mebendazole results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Mebendazole results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il24 interleukin 24 increases expression ISO Mebendazole results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Mebendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Ldha lactate dehydrogenase A decreases activity
affects binding
decreases expression
ISO Mebendazole results in decreased activity of LDHA protein
Mebendazole binds to LDHA protein
Mebendazole results in decreased expression of LDHA mRNA
CTD PMID:37473966 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK1 protein CTD PMID:20848085 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK3 protein CTD PMID:20848085 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK8 protein CTD PMID:20848085 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK9 protein CTD PMID:20848085 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Mebendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Mebendazole results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Mebendazole results in decreased expression of MYC mRNA; Mebendazole results in decreased expression of MYC protein CTD PMID:31207347 PMID:32277947 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Mebendazole results in increased expression of NLRP3 mRNA CTD PMID:24747151 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Mebendazole results in decreased expression of NOTCH1 protein CTD PMID:32277947 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Mebendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Mebendazole results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Mebendazole results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO Mebendazole results in decreased expression of PTK2 protein CTD PMID:30075109 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO Mebendazole results in decreased expression of RAC1 protein CTD PMID:30075109 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Mebendazole results in decreased expression of RHOA protein CTD PMID:30075109 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Mebendazole results in increased expression of S100A8 mRNA CTD PMID:24747151 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Mebendazole results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870
JBrowse link
G Slc2a1 solute carrier family 2 member 1 affects binding
decreases expression
ISO Mebendazole binds to SLC2A1 protein
Mebendazole results in decreased expression of SLC2A1 mRNA
CTD PMID:37473966 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
JBrowse link
G Slc47a1 solute carrier family 47 member 1 decreases expression ISO Mebendazole results in decreased expression of SLC47A1 mRNA CTD PMID:28606429 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Mebendazole results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Mebendazole results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Mebendazole binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO U 0126 inhibits the reaction [Mebendazole results in increased secretion of TNF protein]
Mebendazole results in increased expression of TNF mRNA
CTD PMID:20848085 PMID:24747151 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Mebendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
Mizolastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 decreases expression ISO mizolastine results in decreased expression of ICAM1 CTD PMID:11291777 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO mizolastine results in decreased activity of KCNH2 protein CTD PMID:11082114 PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
nocodazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Nocodazole results in decreased expression of ABCC2 mRNA; Nocodazole results in decreased expression of ABCC2 protein CTD PMID:10691972 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Nocodazole results in increased expression of ABCC3 mRNA CTD PMID:10691972 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO Nocodazole results in increased expression of ACTA2 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Nocodazole results in increased expression of ACTA2 mRNA]
CTD PMID:31170432 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Ahr aryl hydrocarbon receptor decreases activity ISO
EXP
Nocodazole results in decreased activity of AHR protein CTD PMID:16611024 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 multiple interactions ISO Nocodazole promotes the reaction [CCAR1 protein binds to ANAPC2 protein] CTD PMID:21903591 NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:28,484,614...28,496,337
JBrowse link
G Ar androgen receptor multiple interactions
decreases localization
ISO Nocodazole inhibits the reaction [Dihydrotestosterone results in increased localization of AR protein]
Nocodazole results in decreased localization of AR protein
CTD PMID:20807808 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Doxorubicin inhibits the reaction [Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein]]; Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein] CTD PMID:31597699 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions ISO Nocodazole inhibits the reaction [Copper affects the localization of ATP7B protein] CTD PMID:10982773 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein; [bisphenol A analog co-treated with Nocodazole] results in decreased expression of AURKA protein; [bisphenol A co-treated with Nocodazole] results in decreased expression of AURKA protein; MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] CTD PMID:24976383 PMID:35041905 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein CTD PMID:24976383 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Nocodazole analog results in increased expression of BAX protein CTD PMID:28412508 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation
decreases expression
multiple interactions
ISO Nocodazole results in increased phosphorylation of BCL2 protein
Nocodazole analog results in decreased expression of BCL2 protein
TYMP inhibits the reaction [Nocodazole results in increased phosphorylation of BCL2 protein]
CTD PMID:15907805 PMID:28412508 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan] CTD PMID:16373717 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions
increases phosphorylation
ISO [Nocodazole co-treated with Caffeine] results in increased expression of BUB1 protein modified form; chromium hexavalent ion inhibits the reaction [Nocodazole results in increased phosphorylation of BUB1 protein] CTD PMID:21670593 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein increases expression ISO Nocodazole results in increased expression of BUB3 protein CTD PMID:38851359 NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 multiple interactions ISO [CAPZA1 protein co-treated with CAPZA2 protein] results in decreased susceptibility to Nocodazole CTD PMID:22918941 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:195,008,039...195,053,100
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 multiple interactions ISO [CAPZA1 protein co-treated with CAPZA2 protein] results in decreased susceptibility to Nocodazole CTD PMID:22918941 NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
decreases expression
ISO Nocodazole results in increased cleavage of CASP3 protein
[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein; [Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein; Caffeine promotes the reaction [[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein]; NOTCH1 protein mutant form inhibits the reaction [Caffeine promotes the reaction [[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein]]
Nocodazole analog results in decreased expression of CASP3 protein
CTD PMID:21903591 PMID:28412508 PMID:31597699 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO Caspase Inhibitors inhibits the reaction [Nocodazole analog results in increased expression of CASP8 protein modified form]
Nocodazole analog results in increased cleavage of CASP8 protein
CTD PMID:28412508 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases cleavage ISO Nocodazole analog results in increased cleavage of CASP9 protein CTD PMID:28412508 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions
increases expression
ISO Nocodazole inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein]; Nocodazole promotes the reaction [CCAR1 protein binds to ANAPC2 protein]
Nocodazole results in increased expression of CCAR1 protein
CTD PMID:19073175 PMID:21903591 NCBI chr20:31,228,624...31,271,233
Ensembl chr20:31,228,624...31,271,227
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Nocodazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Nocodazole analog results in increased expression of CCNB1 protein; Nocodazole results in increased expression of CCNB1 protein CTD PMID:21670593 PMID:28412508 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO Nocodazole analog results in increased expression of CDK1 protein CTD PMID:28412508 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 multiple interactions ISO [Nocodazole co-treated with chromium hexavalent ion] results in decreased expression of and results in decreased phosphorylation of CDT1 protein CTD PMID:21670593 NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194
JBrowse link
G Cftr CF transmembrane conductance regulator affects localization
multiple interactions
ISO
EXP
Nocodazole affects the localization of CFTR protein
Nocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]
CTD PMID:12529251 PMID:15994425 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO Nocodazole results in decreased expression of CHEK1 protein CTD PMID:26914363 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Nocodazole inhibits the reaction [kaempferol results in increased secretion of CSF2 protein]; Nocodazole inhibits the reaction [Quercetin results in increased secretion of CSF2 protein] CTD PMID:18346843 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
Nocodazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Nocodazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Nocodazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Nocodazole inhibits the reaction [benzotriphenylene results in increased expression of and results in increased activity of CYP1A1 protein]; Nocodazole inhibits the reaction [benzotriphenylene results in increased expression of CYP1A1 mRNA]
CTD PMID:8190110 PMID:16611024 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Nocodazole inhibits the reaction [EGF protein results in increased expression of PSA mRNA] CTD PMID:20807808 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Faslg Fas ligand multiple interactions ISO [TYMP co-treated with Nocodazole] results in decreased expression of FASLG mRNA; [TYMP co-treated with Nocodazole] results in decreased expression of FASLG protein CTD PMID:15907805 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fbxo5 F-box protein 5 multiple interactions ISO [Nocodazole co-treated with chromium hexavalent ion] results in decreased expression of FBXO5 protein CTD PMID:21670593 NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Nocodazole results in increased expression of FIS1 protein CTD PMID:26732598 NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
JBrowse link
G Gmnn geminin, DNA replication inhibitor multiple interactions ISO [Nocodazole co-treated with chromium hexavalent ion] results in increased ubiquitination of GMNN protein CTD PMID:21670593 NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,729,824...40,738,068
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Nocodazole results in increased expression of H2AX protein modified form CTD PMID:26914363 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression ISO Nocodazole results in decreased expression of HAMP mRNA CTD PMID:25633564 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Nocodazole results in increased expression of HSPA5 protein CTD PMID:26732598 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Nocodazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:33377310 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Nocodazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Nocodazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:33377310 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Nocodazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
multiple interactions
ISO Nocodazole results in increased phosphorylation of JUN protein
TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of JUN protein]
CTD PMID:12221076 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO Nocodazole inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA] CTD PMID:20807808 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 decreases response to substance ISO LCMT1 results in decreased susceptibility to Nocodazole CTD PMID:17724024 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 affects response to substance ISO LZTS1 protein affects the susceptibility to Nocodazole CTD PMID:17349584 NCBI chr16:25,309,502...25,364,942
Ensembl chr16:25,309,507...25,364,940
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nocodazole results in increased phosphorylation of and results in increased activity of MAPK1 protein; TYMP affects the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Nocodazole inhibits the reaction [NGF protein results in increased activity of MAPK1 protein]
CTD PMID:15907805 PMID:17822405 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nocodazole results in increased phosphorylation of and results in increased activity of MAPK3 protein; TYMP affects the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Nocodazole inhibits the reaction [NGF protein results in increased activity of MAPK3 protein]
CTD PMID:15907805 PMID:17822405 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Nocodazole results in increased phosphorylation of MAPK9 protein
TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK9 protein]
CTD PMID:12221076 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Nocodazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Myt1 myelin transcription factor 1 increases phosphorylation ISO Nocodazole results in increased phosphorylation of MYT1 protein CTD PMID:16611024 NCBI chr 3:189,263,569...189,327,844
Ensembl chr 3:189,263,467...189,327,844
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Nocodazole results in decreased expression of NANOG protein CTD PMID:21559451 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Nocodazole inhibits the reaction [NGF protein affects the localization of NTRK1 protein]; Nocodazole inhibits the reaction [NGF protein affects the localization of RAP1A protein]; Nocodazole inhibits the reaction [NGF protein results in increased activity of MAPK1 protein]; Nocodazole inhibits the reaction [NGF protein results in increased activity of MAPK3 protein]; Nocodazole inhibits the reaction [NGF protein results in increased activity of RAP1A protein] CTD PMID:17822405 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
JBrowse link
G Notch1 notch receptor 1 decreases expression
multiple interactions
ISO Nocodazole results in decreased expression of NOTCH1 protein
BI 2536 inhibits the reaction [Nocodazole results in decreased expression of NOTCH1 protein]; Doxorubicin inhibits the reaction [Nocodazole promotes the reaction [Hydroxyurea results in decreased expression of NOTCH1 protein]]; Nocodazole promotes the reaction [Hydroxyurea results in decreased expression of NOTCH1 protein]; NOTCH1 protein mutant form inhibits the reaction [Caffeine promotes the reaction [[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein]]
CTD PMID:31597699 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 multiple interactions ISO Nocodazole inhibits the reaction [NPC1 protein results in increased secretion of Daunorubicin] CTD PMID:16174794 NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800
JBrowse link
G Npm1 nucleophosmin 1 affects phosphorylation ISO Nocodazole affects the phosphorylation of NPM1 protein CTD PMID:15190079 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr  X:18,245,740...18,256,024
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Nocodazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions EXP Nocodazole inhibits the reaction [NGF protein affects the localization of NTRK1 protein] CTD PMID:17822405 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
JBrowse link
G Optn optineurin affects localization ISO Nocodazole affects the localization of OPTN protein CTD PMID:25096716 NCBI chr17:78,118,847...78,169,543
Ensembl chr17:78,118,866...78,169,543
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO TYMP inhibits the reaction [Nocodazole results in increased cleavage of PARP1 protein]
Nocodazole analog results in increased cleavage of PARP1 protein; Nocodazole results in increased cleavage of PARP1 protein
CTD PMID:15907805 PMID:21903591 PMID:28412508 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions
decreases phosphorylation
ISO [Hydroxyurea co-treated with Nocodazole] affects the expression of and affects the phosphorylation of PLK1 protein; Doxorubicin affects the reaction [[Hydroxyurea co-treated with Nocodazole] affects the expression of and affects the phosphorylation of PLK1 protein]
Nocodazole results in decreased phosphorylation of PLK1 protein
CTD PMID:31597699 NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Nocodazole results in decreased expression of POU5F1 protein CTD PMID:21559451 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases response to substance ISO PPP2R2A results in decreased susceptibility to Nocodazole CTD PMID:17724024 NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405
JBrowse link
G Qrich1 glutamine-rich 1 multiple interactions
increases phosphorylation
ISO Genistein inhibits the reaction [Nocodazole results in increased phosphorylation of QRICH1 protein] CTD PMID:17510977 NCBI chr 8:118,095,435...118,135,001
Ensembl chr 8:118,095,429...118,134,999
JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions ISO Nocodazole results in increased phosphorylation of [SUMO1 protein binds to RANGAP1 protein] CTD PMID:21646468 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions EXP Nocodazole inhibits the reaction [NGF protein affects the localization of RAP1A protein]; Nocodazole inhibits the reaction [NGF protein results in increased activity of RAP1A protein] CTD PMID:17822405 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Nocodazole inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein] CTD PMID:29247640 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Nocodazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO Nocodazole results in increased phosphorylation of [SUMO1 protein binds to RANGAP1 protein] CTD PMID:21646468 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890
JBrowse link
G Tf transferrin decreases expression ISO Nocodazole results in decreased expression of TRF protein CTD PMID:34089742 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Nocodazole inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Nocodazole inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:33377310 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of JUN protein]; TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein]; TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK9 protein]
Nocodazole analog results in increased expression of TP53 protein; Nocodazole results in increased expression of TP53 protein
CTD PMID:12221076 PMID:21559451 PMID:28412508 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tuba1a tubulin, alpha 1A multiple interactions ISO Nocodazole inhibits the reaction [TUBA1A protein binds to TUBA1A protein] CTD PMID:19222062 NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [TYMP co-treated with Nocodazole] results in decreased expression of FASLG mRNA; [TYMP co-treated with Nocodazole] results in decreased expression of FASLG protein; TYMP affects the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK1 protein]; TYMP affects the reaction [Nocodazole results in increased phosphorylation of and results in increased activity of MAPK3 protein]; TYMP inhibits the reaction [Nocodazole results in increased cleavage of PARP1 protein]; TYMP inhibits the reaction [Nocodazole results in increased phosphorylation of BCL2 protein] CTD PMID:15907805 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Nocodazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
NS 1619 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]] CTD PMID:21413024 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions ISO NS 1619 inhibits the reaction [Oxygen deficiency results in increased expression of FLT1 protein]; paxilline inhibits the reaction [NS 1619 inhibits the reaction [Oxygen deficiency results in increased expression of FLT1 protein]] CTD PMID:25371888 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions ISO NS 1619 binds to and results in increased activity of KCNMA1 protein; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; NS 1619 inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]] CTD PMID:21413024 NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 multiple interactions ISO NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; NS 1619 inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]] CTD PMID:21413024 NCBI chr10:19,062,014...19,119,005
Ensembl chr10:19,062,291...19,073,204
JBrowse link
omeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Omeprazole results in increased expression of ABCA1 mRNA CTD PMID:20060385 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Omeprazole results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of ABCB1A mRNA
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]
Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1A protein]
CTD PMID:19483382 PMID:30452898 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Omeprazole results in increased susceptibility to Cisplatin] which results in decreased expression of ABCC2 protein CTD PMID:35447140 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Omeprazole results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Omeprazole affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions
ISO Omeprazole results in increased expression of ABCG2 mRNA alternative form; Omeprazole results in increased expression of ABCG2 protein
Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow]
CTD PMID:20804740 PMID:31348918 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression EXP Omeprazole affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Omeprazole affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Omeprazole affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Omeprazole affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,775,016...9,781,447 JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression EXP Omeprazole affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Omeprazole affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP
ISO
Omeprazole results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596
JBrowse link
G Aco1 aconitase 1 affects expression EXP Omeprazole affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
JBrowse link
G Aco2 aconitase 2 affects expression EXP Omeprazole affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression EXP Omeprazole affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Omeprazole affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Omeprazole affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
JBrowse link
G Add1 adducin 1 affects expression EXP Omeprazole affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Omeprazole affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Omeprazole affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622
JBrowse link
G Afm afamin affects expression EXP Omeprazole affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
JBrowse link
G Agt angiotensinogen affects expression EXP Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases activity
increases activity
increases expression
decreases expression
affects localization
increases response to substance
ISO
EXP
AG-879 inhibits the reaction [Omeprazole results in increased activity of AHR protein]; AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of AHR mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein]; Omeprazole binds to and results in increased activity of AHR protein; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; Puromycin inhibits the reaction [Omeprazole results in increased expression of AHR protein]
Omeprazole results in decreased activity of AHR protein
Omeprazole affects the localization of AHR protein
AHR protein results in increased susceptibility to Omeprazole
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
CTD PMID:9139728 PMID:9395520 PMID:14742684 PMID:16109480 PMID:20171196 More... NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression
multiple interactions
EXP Omeprazole affects the expression of AKR7A3 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ALDH1A1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Omeprazole results in increased expression of ALDH1A3 mRNA CTD PMID:12040753 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP Omeprazole affects the expression of ALDH1A7 mRNA CTD PMID:19483382 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Omeprazole affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO Omeprazole results in increased expression of ALDH3A1 mRNA CTD PMID:12040753 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Omeprazole affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Omeprazole affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Omeprazole affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Omeprazole affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
JBrowse link
G Apoh apolipoprotein H affects expression EXP Omeprazole affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Omeprazole affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:81,569,960...81,635,906
Ensembl chr  X:81,570,053...81,640,036
JBrowse link
G Arg1 arginase 1 affects expression EXP Omeprazole affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 affects expression EXP Omeprazole affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
affects localization
ISO
EXP
Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]
Omeprazole affects the localization of ARNT protein
Omeprazole affects the localization of [ARNT protein co-treated with AHR protein]
CTD PMID:9395520 PMID:21703235 PMID:25826687 NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Omeprazole affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Omeprazole affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Omeprazole affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Omeprazole affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Omeprazole affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
CTD PMID:25337692 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Omeprazole affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:30452898 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Omeprazole inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:30452898 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Omeprazole affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression EXP Omeprazole affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Omeprazole affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
JBrowse link
G Bmx BMX non-receptor tyrosine kinase multiple interactions ISO BMX mRNA affects the reaction [Omeprazole results in increased activity of AHR protein] CTD PMID:21861773 NCBI chr  X:33,859,128...33,921,876
Ensembl chr  X:33,859,129...33,921,874
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Omeprazole affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Omeprazole affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125
Ensembl chr13:31,394,011...31,401,125
JBrowse link
G C1qa complement C1q A chain decreases expression EXP Omeprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Omeprazole affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Omeprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C1s complement C1s affects expression EXP Omeprazole affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Omeprazole affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:50,694,680...50,759,096
Ensembl chr11:50,694,563...50,759,016
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression
decreases expression
EXP Omeprazole affects the expression of C4BPA mRNA
Omeprazole results in decreased expression of C4BPA mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Omeprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
JBrowse link
G C7 complement C7 affects expression EXP Omeprazole affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
JBrowse link
G C8b complement C8 beta chain affects expression EXP Omeprazole affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Omeprazole affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Omeprazole affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Omeprazole affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Omeprazole affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
affects expression
increases cleavage
ISO
EXP
Omeprazole analog results in increased activity of CASP3 protein; Omeprazole results in increased activity of CASP3 protein
Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
Omeprazole inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of CASP3 mRNA]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
Omeprazole affects the expression of CASP3 mRNA
Omeprazole results in increased cleavage of CASP3 protein
CTD PMID:15461867 PMID:18336733 PMID:19251492 PMID:19483382 PMID:25637687 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP
ISO
Omeprazole results in increased activity of CAT protein
Omeprazole inhibits the reaction [Ethanol results in decreased activity of CAT protein]
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of CAT protein]
CTD PMID:18547560 PMID:28849987 PMID:33245926 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Omeprazole affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Omeprazole results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Omeprazole affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Omeprazole affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:196,682,455...196,724,430
Ensembl chr 2:196,681,681...196,723,812
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Omeprazole affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
JBrowse link
G Cfi complement factor I affects expression
decreases expression
EXP Omeprazole affects the expression of CFI mRNA
Omeprazole results in decreased expression of CFI mRNA
CTD PMID:19483382 PMID:25626140 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
JBrowse link
G Cftr CF transmembrane conductance regulator affects metabolic processing ISO CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Omeprazole affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Omeprazole affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Omeprazole affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:27,290,769...27,356,967
Ensembl chr  X:27,290,868...27,356,939
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Omeprazole affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Omeprazole affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression EXP Omeprazole affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Omeprazole affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Omeprazole affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Omeprazole affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,382,897...9,413,216
Ensembl chr14:9,382,900...9,413,107
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression EXP Omeprazole affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:40,226,368...40,257,617
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Omeprazole affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Omeprazole affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Omeprazole affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Omeprazole affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Omeprazole affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Omeprazole affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Omeprazole affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
JBrowse link
G Ctsb cathepsin B decreases activity ISO Omeprazole results in decreased activity of CTSB protein CTD PMID:34871754 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein] CTD PMID:20165931 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
JBrowse link
G Ctse cathepsin E decreases expression EXP Omeprazole results in decreased expression of CTSE CTD PMID:7575556 NCBI chr13:45,644,168...45,666,722
Ensembl chr13:45,644,147...45,666,722
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions
ISO Omeprazole results in decreased expression of CXCR4 mRNA
AHR protein affects the reaction [Omeprazole results in decreased expression of CXCR4 mRNA]
CTD PMID:25826687 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
decreases activity
increases expression
ISO
EXP
Omeprazole results in increased activity of CYP1A1 promoter
Omeprazole inhibits the reaction [Oxygen results in increased expression of CYP1A1 protein]; Omeprazole promotes the reaction [Oxygen results in decreased expression of CYP1A1 mRNA]
Omeprazole results in decreased activity of CYP1A1 protein
Omeprazole results in increased expression of CYP1A1 mRNA; Omeprazole results in increased expression of CYP1A1 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [Omeprazole results in increased expression of CYP1A1 protein]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Genistein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; lavendustin A inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Staurosporine inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]
AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein mutant form inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Omeprazole results in decreased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; Omeprazole promotes the reaction [AHR protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]
CTD PMID:8647108 PMID:8900397 PMID:9041675 PMID:9139728 PMID:9152597 More... NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
decreases activity
multiple interactions
ISO
EXP
Omeprazole results in increased activity of CYP1A2 promoter; Omeprazole results in increased activity of CYP1A2 protein
Omeprazole results in increased expression of CYP1A2 mRNA; Omeprazole results in increased expression of CYP1A2 protein
Omeprazole results in decreased activity of CYP1A2 protein
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA
[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin; AHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]; Omeprazole results in increased expression of and results in increased activity of CYP1A2 protein
CTD PMID:9152597 PMID:9744552 PMID:12040753 PMID:12623754 PMID:12841937 More... NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
affects expression
decreases activity
increases expression
ISO Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]
Omeprazole affects the expression of CYP1B1 mRNA
Omeprazole results in decreased activity of CYP1B1 protein
Omeprazole results in increased expression of CYP1B1 mRNA
CTD PMID:12040753 PMID:12623754 PMID:18420780 PMID:21703235 PMID:25826687 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Omeprazole results in increased expression of CYP2B1 mRNA; Omeprazole results in increased expression of CYP2B1 protein CTD PMID:9152597 PMID:19118567 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
affects expression
EXP Omeprazole results in increased expression of CYP2B2 protein
Omeprazole affects the expression of CYP2B2 mRNA
CTD PMID:9152597 PMID:19483382 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
decreases activity
increases expression
increases activity
EXP
ISO
Omeprazole affects the expression of CYP2B3 mRNA
Omeprazole results in decreased activity of CYP2B10 protein
Omeprazole results in increased expression of CYP2B6 mRNA
Omeprazole results in increased activity of CYP2B6 protein
CTD PMID:17954527 PMID:18420780 PMID:19118567 PMID:19483382 PMID:22524704 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases metabolic processing
decreases activity
multiple interactions
increases hydroxylation
increases metabolic processing
affects metabolic processing
ISO CYP2C19 gene alternative form results in decreased metabolism of Omeprazole
Omeprazole results in decreased activity of CYP2C19 protein
[5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-chlorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-fluorotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [7-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite; [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite; [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole; Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin]; Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Fluoxetine]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of 2-oxo-clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of Clopidogrel]
CYP2C19 protein results in increased hydroxylation of Omeprazole
CYP2C19 protein results in increased metabolism of Omeprazole
CYP2C19 protein affects the metabolism of Omeprazole
CTD PMID:8930576 PMID:9600717 PMID:11752104 PMID:12464242 PMID:12467917 More... NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 increases expression EXP Omeprazole results in increased expression of CYP2D9 mRNA CTD PMID:19118567 NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Omeprazole affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:115,797,785...115,802,142
Ensembl chr 7:115,797,789...115,802,158
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
decreases activity
EXP
ISO
Omeprazole affects the expression of CYP2D4 mRNA
Omeprazole results in decreased activity of CYP2D6 protein
CTD PMID:18420780 PMID:19483382 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 PMID:36243147 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression EXP Omeprazole affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Omeprazole affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
increases metabolic processing
multiple interactions
increases expression
ISO CYP3A4 protein affects the metabolism of Omeprazole
CYP3A4 protein results in increased metabolism of Omeprazole
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]; Omeprazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Omeprazole results in increased expression of and results in increased activity of CYP3A4 protein
Omeprazole results in increased expression of CYP3A4 mRNA; Omeprazole results in increased expression of CYP3A4 protein
CTD PMID:7870052 PMID:8930576 PMID:9744552 PMID:12235278 PMID:12485723 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
increases expression
EXP Omeprazole affects the expression of CYP3A23-3A1 mRNA
Omeprazole results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
increases expression
EXP
ISO
Omeprazole affects the expression of CYP3A9 mRNA
Omeprazole results in increased expression of CYP3A5 mRNA
CTD PMID:19118567 PMID:19483382 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Omeprazole affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Omeprazole affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP Omeprazole affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Omeprazole affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Omeprazole affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,504,730...106,506,619 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Omeprazole results in increased expression of DDIT3 protein CTD PMID:27358234 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Omeprazole affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
JBrowse link
G Dexi Dexi homolog affects expression EXP Omeprazole affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression EXP Omeprazole affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Omeprazole affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Omeprazole affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Omeprazole affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:46,003,845...46,036,498
Ensembl chr10:46,003,845...46,036,499
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Omeprazole affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Omeprazole affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression EXP Omeprazole affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Omeprazole affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Omeprazole affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Omeprazole affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:186,025,740...186,057,165 JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Omeprazole affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Omeprazole affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Omeprazole affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Omeprazole affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Omeprazole promotes the reaction [Indomethacin results in increased expression of EGF protein] CTD PMID:18431645 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression EXP Omeprazole affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Omeprazole affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression EXP Omeprazole affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Omeprazole affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Omeprazole affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
JBrowse link
G Eno1 enolase 1 affects expression EXP Omeprazole affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Omeprazole affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Omeprazole affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Omeprazole promotes the reaction [EP300 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Omeprazole affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Omeprazole affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
JBrowse link
G Esd esterase D affects expression EXP Omeprazole affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Omeprazole affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Omeprazole affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP Omeprazole affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Omeprazole affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Omeprazole affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Omeprazole affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Omeprazole affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Omeprazole affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Omeprazole affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gast gastrin increases expression ISO
EXP
Omeprazole results in increased expression of GAST protein CTD PMID:11422300 PMID:12189558 PMID:12763636 PMID:15223672 PMID:16618411 More... NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Omeprazole affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Omeprazole affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Omeprazole affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GGT1 mRNA CTD PMID:22687989 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Omeprazole affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:70,541,862...70,549,843
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Omeprazole affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Omeprazole affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA CTD PMID:22687989 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Omeprazole affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Omeprazole affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Omeprazole affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression
multiple interactions
EXP Omeprazole results in increased expression of GSTA5 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
CTD PMID:17202759 PMID:22687989 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Omeprazole results in increased expression of GSTP1 mRNA CTD PMID:19118567 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Omeprazole affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Omeprazole affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
JBrowse link
G Gulo gulonolactone (L-) oxidase affects expression EXP Omeprazole affects the expression of GULO mRNA CTD PMID:19483382 NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422
JBrowse link
G Gzma granzyme A affects expression EXP Omeprazole affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Omeprazole affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Omeprazole affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression
multiple interactions
increases secretion
ISO Omeprazole results in increased expression of HAMP mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Omeprazole results in increased expression of HAMP mRNA]; AHR protein affects the reaction [Omeprazole results in increased expression of HAMP mRNA]
Omeprazole results in increased expression of HAMP mRNA; Omeprazole results in increased expression of HAMP protein
Omeprazole results in increased secretion of HAMP protein
CTD PMID:31669099 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Omeprazole affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Omeprazole affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Omeprazole affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
JBrowse link
G Hdc histidine decarboxylase affects expression
increases stability
increases expression
multiple interactions
EXP Omeprazole affects the expression of HDC mRNA
Omeprazole results in increased stability of HDC protein
Omeprazole results in increased expression of HDC mRNA
Omeprazole results in increased expression of and results in increased activity of HDC protein
CTD PMID:12763636 PMID:19483382 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Omeprazole affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Omeprazole affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein]; Omeprazole results in increased expression of and results in increased activity of HMOX1 protein
Omeprazole results in increased expression of HMOX1 mRNA; Omeprazole results in increased expression of HMOX1 protein
CTD PMID:16712795 PMID:27725188 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Omeprazole affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Omeprazole affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:106,417,902...106,457,220
Ensembl chr 1:106,417,902...106,452,859
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Omeprazole affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Omeprazole affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions
EXP Omeprazole results in decreased expression of HSPA1A mRNA; Omeprazole results in decreased expression of HSPA1A protein
Zinc Compounds analog inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
CTD PMID:15223672 PMID:16945336 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Omeprazole affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Omeprazole co-treated with CCKBR protein] results in increased expression of IER3 CTD PMID:17704804 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
JBrowse link
G Ifng interferon gamma multiple interactions ISO Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] CTD PMID:19232345 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression EXP Omeprazole affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Omeprazole affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 PMID:38341112 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il16 interleukin 16 multiple interactions EXP Omeprazole inhibits the reaction [Ethanol results in increased expression of IL16 protein] CTD PMID:38341112 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL1B protein] CTD PMID:32418911 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of IL6 protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of IL6 protein]
Omeprazole inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:25637687 PMID:32418911 PMID:38341112 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Omeprazole affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:93,370,200...93,391,474
Ensembl chr 2:93,370,299...93,391,468
JBrowse link
G Inhbe inhibin subunit beta E affects expression EXP Omeprazole affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Omeprazole affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Omeprazole affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Omeprazole affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:16,252,424...16,270,737
Ensembl chr12:16,252,424...16,270,719
JBrowse link
G Kdr kinase insert domain receptor affects expression
multiple interactions
EXP
ISO
Omeprazole affects the expression of KDR mRNA
Omeprazole promotes the reaction [Oxygen results in decreased expression of KDR protein]
CTD PMID:19483382 PMID:26272953 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
JBrowse link
G Krt8 keratin 8 affects expression EXP Omeprazole affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Omeprazole affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Omeprazole affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Omeprazole affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
JBrowse link
G Lox lysyl oxidase affects expression EXP Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Omeprazole affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Omeprazole affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Omeprazole affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein] CTD PMID:17406807 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Omeprazole affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705
JBrowse link
G Me1 malic enzyme 1 affects expression
multiple interactions
EXP Omeprazole affects the expression of ME1 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA
CTD PMID:19483382 PMID:22687989 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein] CTD PMID:16934674 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Omeprazole inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein] CTD PMID:16934674 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Omeprazole affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO
EXP
Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein]
Omeprazole results in decreased activity of MPO protein
Omeprazole inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Ethanol results in increased activity of MPO protein]; Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein]
CTD PMID:16091555 PMID:17151854 PMID:20165931 PMID:25637687 PMID:27780710 More... NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mro maestro affects expression EXP Omeprazole affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:69,723,764...69,742,815
Ensembl chr18:69,725,798...69,743,031
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Omeprazole affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:21,830,834...21,834,607
Ensembl chr 9:21,830,835...21,834,641
JBrowse link
G Mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Omeprazole affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777
JBrowse link
G Mug2 murinoglobulin 2 affects expression EXP Omeprazole affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:156,836,140...156,908,972 JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Omeprazole affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Omeprazole affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
JBrowse link
G Myo1d myosin ID affects expression EXP Omeprazole affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Omeprazole affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Omeprazole affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Omeprazole affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Omeprazole promotes the reaction [NCOA1 protein binds to CYP1A1 promoter]; Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] CTD PMID:21703235 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP Omeprazole affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Omeprazole affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909
Ensembl chr 5:184,849,197...185,028,909
Ensembl chr14:184,849,197...185,028,909
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Omeprazole affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Omeprazole affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:95,696,507...95,715,208
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Omeprazole results in increased expression of HMOX1 protein] CTD PMID:27725188 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Omeprazole inhibits the reaction [Cisplatin results in decreased expression of NFKBIA protein] CTD PMID:32418911 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Omeprazole affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Omeprazole affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:67,659,628...67,771,105
Ensembl chr 7:67,659,628...67,769,959
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Omeprazole affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Omeprazole affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP
ISO
Omeprazole results in increased expression of NQO1 mRNA
Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 mRNA]; Omeprazole inhibits the reaction [Oxygen results in increased expression of NQO1 protein]
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA
CTD PMID:17202759 PMID:22687989 PMID:26272953 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO
EXP
[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA] CTD PMID:12695340 PMID:17041008 PMID:25680588 PMID:26187274 PMID:27732639 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression
decreases metabolic processing
increases expression
EXP
ISO
Omeprazole affects the expression of NR1I3 mRNA
NR1I3 gene mutant form results in decreased metabolism of Omeprazole
Omeprazole results in increased expression of NR1I3 mRNA
CTD PMID:19118567 PMID:19483382 PMID:27434302 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Omeprazole affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
JBrowse link
G Oaf out at first homolog affects expression EXP Omeprazole affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Omeprazole affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Omeprazole affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Omeprazole affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Omeprazole affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Omeprazole affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:15,126,358...15,239,555
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Omeprazole affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Omeprazole affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Omeprazole results in increased cleavage of PARP1 protein CTD PMID:15461867 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Omeprazole affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Omeprazole affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Omeprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein]
Omeprazole inhibits the reaction [Ethanol results in decreased expression of PCNA protein]
CTD PMID:19251492 PMID:26970604 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP Omeprazole affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Omeprazole affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Omeprazole affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Omeprazole affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression EXP Omeprazole affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Omeprazole affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Omeprazole affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Omeprazole affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Omeprazole affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Omeprazole affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
JBrowse link
G Pla2g4a phospholipase A2 group 4A increases phosphorylation
multiple interactions
ISO Omeprazole results in increased phosphorylation of PLA2G4A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Omeprazole results in increased phosphorylation of PLA2G4A protein]
CTD PMID:25797602 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Omeprazole affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488
JBrowse link
G Plg plasminogen affects expression EXP Omeprazole affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
JBrowse link
G Pls3 plastin 3 affects expression EXP Omeprazole affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:116,401,247...116,495,898
Ensembl chr  X:116,401,293...116,495,893
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Omeprazole affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996
JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions EXP
ISO
Omeprazole inhibits the reaction [Cisplatin results in increased expression of POU2F2 protein] CTD PMID:30452898 NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Omeprazole affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Omeprazole affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
JBrowse link
G Prl prolactin increases expression ISO Omeprazole results in increased expression of PRL protein CTD PMID:20726208 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Omeprazole affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Omeprazole affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Omeprazole affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Omeprazole affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Omeprazole affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Omeprazole affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Omeprazole affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Omeprazole affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Omeprazole affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 affects expression EXP Omeprazole affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
[Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein
Omeprazole inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]
CTD PMID:23038005 PMID:26970604 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptms parathymosin affects expression EXP Omeprazole affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Omeprazole affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Omeprazole affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Omeprazole affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Omeprazole affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[Omeprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of RELA protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]
Omeprazole inhibits the reaction [Cisplatin affects the localization of RELA protein]
CTD PMID:19251492 PMID:30452898 PMID:32418911 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Retsat retinol saturase increases expression EXP Omeprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Omeprazole affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Omeprazole affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Omeprazole affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:105,084,762...105,100,839
Ensembl chr 4:105,084,686...105,106,809
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Omeprazole affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Omeprazole affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Omeprazole affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Omeprazole affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Omeprazole affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638
Ensembl chr18:111,722,010...111,722,638
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Omeprazole affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Omeprazole affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Omeprazole affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:150,536,650...150,540,214
Ensembl chr 4:150,536,646...150,540,214
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Omeprazole affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
JBrowse link
G Rpn2 ribophorin II affects expression EXP Omeprazole affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:166,361,955...166,409,272
Ensembl chr 3:166,362,049...166,409,922
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Omeprazole affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Omeprazole affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Omeprazole affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Omeprazole affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621
Ensembl chr 9:42,839,965...43,095,621
Ensembl chr 5:42,839,965...43,095,621
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Omeprazole affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Omeprazole affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Omeprazole affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
JBrowse link
G Rras2 RAS related 2 affects expression EXP Omeprazole affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
JBrowse link
G RT1-DMa RT1 class II, locus DMa affects expression ISO Omeprazole affects the expression of HLA-DMA mRNA CTD PMID:25811541 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Omeprazole affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Omeprazole affects the expression of RT1-S3 mRNA CTD PMID:19483382 NCBI chr20:2,675,463...2,680,229 JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Omeprazole affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Omeprazole affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:8,186,004...8,216,576
Ensembl chr 5:8,185,985...8,218,898
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Omeprazole affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Omeprazole affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Omeprazole affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:59,841,090...59,850,641
Ensembl chr 8:59,841,090...59,850,641
JBrowse link
G Sell selectin L decreases expression EXP Omeprazole results in decreased expression of SELL protein CTD PMID:17652263 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Omeprazole affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Omeprazole affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
JBrowse link
G Serpina10 serpin family A member 10 affects expression EXP Omeprazole affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Omeprazole affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Omeprazole affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP Omeprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Omeprazole affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Omeprazole affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression EXP Omeprazole affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions EXP Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine] CTD PMID:19041296 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Omeprazole affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Omeprazole affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Omeprazole affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Omeprazole affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Omeprazole affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO Omeprazole results in decreased expression of SLC40A1 protein CTD PMID:31669099 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Omeprazole affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Omeprazole affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:75,976,000...76,014,651
Ensembl chr18:75,977,458...76,014,651
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Omeprazole affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 affects expression EXP Omeprazole affects the expression of SLCO1A1 mRNA CTD PMID:19483382 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO Omeprazole results in increased expression of SLCO1A2 mRNA CTD PMID:19118567 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Omeprazole inhibits the reaction [Ethanol results in decreased activity of SOD1 protein] CTD PMID:28849987 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Omeprazole affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:134,605,750...134,646,752
JBrowse link
G Srm spermidine synthase affects expression EXP Omeprazole affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Omeprazole affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:112,647,577...112,661,524 JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Omeprazole affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Omeprazole affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression EXP Omeprazole affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 4:106,866,329...106,895,686
Ensembl chr 4:106,866,114...106,895,689
JBrowse link
G Surf4 surfeit 4 affects expression EXP Omeprazole affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:30,646,435...30,659,641
Ensembl chr 3:30,638,299...30,661,390
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Omeprazole affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:106,920,970...106,966,543
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Omeprazole inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Omeprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Omeprazole affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Omeprazole affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Omeprazole affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:80,589,775...80,594,237
Ensembl chr18:80,589,783...80,594,237
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Omeprazole inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein] CTD PMID:16934674 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Omeprazole affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased expression of TLR4 protein] CTD PMID:32418911 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Omeprazole affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 affects expression EXP Omeprazole affects the expression of TEGT mRNA CTD PMID:19483382 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Omeprazole affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Omeprazole affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Omeprazole affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:41,505,167...41,512,243
Ensembl chr18:41,478,539...41,512,243
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Omeprazole affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Omeprazole affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818
JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression EXP Omeprazole results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:50,403,707...50,443,224
Ensembl chr11:50,398,349...50,443,114
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Omeprazole inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
Omeprazole inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in decreased expression of TNF protein]; Omeprazole inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:19232345 PMID:25637687 PMID:26970604 PMID:30452898 PMID:32418911 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Omeprazole affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Omeprazole affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
JBrowse link
G Tyr tyrosinase multiple interactions
decreases expression
ISO Omeprazole affects the N-linked glycosylation of and results in increased degradation of TYR protein; Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein]
Omeprazole results in decreased expression of TYR protein
CTD PMID:25337692 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Omeprazole affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr16:18,952,583...18,954,780 JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Omeprazole affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:32,041,190...32,071,252 JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Omeprazole affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
affects expression
ISO
EXP
Omeprazole results in increased expression of UGT1A1 mRNA
Omeprazole affects the expression of UGT1A1 mRNA
CTD PMID:19118567 PMID:19483382 PMID:25626140 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Omeprazole results in increased expression of UGT1A2 mRNA; Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 increases expression ISO Omeprazole results in increased expression of UGT1A5 mRNA CTD PMID:19118567 NCBI chr 9:96,228,134...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases expression ISO Omeprazole results in increased expression of UGT1A4 mRNA CTD PMID:19118567 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
multiple interactions
EXP
ISO
Omeprazole results in increased expression of UGT1A6 mRNA
[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
CTD PMID:19118567 PMID:22687989 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO Omeprazole results in increased expression of UGT1A9 mRNA CTD PMID:19118567 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Omeprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Omeprazole affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,955,764...9,959,047
JBrowse link
G Vnn1 vanin 1 affects expression EXP Omeprazole affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Omeprazole affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:95,462,017...95,503,826
Ensembl chr13:95,462,020...95,503,738
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Omeprazole affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Omeprazole affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:70,224,581...70,240,971
Ensembl chr11:70,225,045...70,240,102
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Omeprazole affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
JBrowse link
Omeprazole sulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
omeprazole sulfide binds to and affects the folding of AHR protein; omeprazole sulfide binds to and results in decreased activity of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]
CTD PMID:16109480 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
omeprazole sulfide results in increased expression of CYP1A1 mRNA
CTD PMID:16109480 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of omeprazole sulfide CTD PMID:16109480 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
oxatomide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO oxatomide results in decreased activity of CYP2D6 protein CTD PMID:15684493 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
decreases activity
ISO CYP3A4 protein results in increased metabolism of oxatomide
oxatomide results in decreased activity of CYP3A4 protein
CTD PMID:15684493 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Hexb hexosaminidase subunit beta affects secretion EXP oxatomide affects the secretion of HEXB protein CTD PMID:7655991 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO oxatomide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
oxfendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
decreases activity
multiple interactions
ISO ABCG2 protein affects the transport of oxfendazole
oxfendazole results in decreased activity of ABCG2 protein
oxfendazole inhibits the reaction [ABCG2 protein affects the transport of Mitoxantrone]
CTD PMID:15703302 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of AKR7A3 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of AKR7A3 mRNA] CTD PMID:18754104 PMID:20033131 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
JBrowse link
G Casp3 caspase 3 increases cleavage EXP oxfendazole results in increased cleavage of CASP3 protein CTD PMID:26558467 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP oxfendazole results in increased expression of CDKN1A protein CTD PMID:26558467 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Chek1 checkpoint kinase 1 affects expression EXP oxfendazole affects the expression of CHEK1 mRNA CTD PMID:26558467 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 protein; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA] CTD PMID:18754104 PMID:20033131 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A2 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA CTD PMID:18754104 PMID:20033131 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA]; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GPX2 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GPX2 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA CTD PMID:18754104 PMID:20033131 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; [Melatonin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA CTD PMID:18754104 PMID:20033131 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA CTD PMID:18754104 PMID:20033131 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression EXP oxfendazole results in decreased expression of MAD2L1 mRNA CTD PMID:26558467 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases phosphorylation
increases expression
EXP oxfendazole results in decreased phosphorylation of MDM2 protein
oxfendazole results in increased expression of MDM2 mRNA
CTD PMID:26558467 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:18754104 PMID:20033131 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP oxfendazole results in decreased expression of MKI67 protein CTD PMID:26558467 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of NQO1 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of NQO1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA CTD PMID:18754104 PMID:20033131 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO oxfendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP oxfendazole results in decreased expression of TOP2A protein CTD PMID:26558467 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
G Tp53 tumor protein p53 decreases expression EXP oxfendazole results in decreased expression of TP53 mRNA CTD PMID:26558467 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
pantoprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO pantoprazole results in increased expression of ABCA1 mRNA CTD PMID:20060385 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO pantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12702717 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO pantoprazole inhibits the reaction [ABCG2 protein affects the transport of 7-hydroxymethotrexate] CTD PMID:17032904 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G C1qa complement C1q A chain decreases expression EXP pantoprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C1qc complement C1q C chain decreases expression EXP pantoprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP pantoprazole results in decreased expression of C4BPA mRNA CTD PMID:25626140 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP pantoprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
JBrowse link
G Casp3 caspase 3 multiple interactions EXP pantoprazole inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] CTD PMID:18853145 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Pantoprazole results in increased expression of CEBPA protein CTD PMID:39004236 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
JBrowse link
G Cfi complement factor I decreases expression EXP pantoprazole results in decreased expression of CFI mRNA CTD PMID:25626140 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases expression
EXP pantoprazole results in increased expression of CYP1A1 protein
pantoprazole results in decreased expression of CYP1A1 mRNA
CTD PMID:9152597 PMID:25626140 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP pantoprazole results in increased expression of CYP1A2 mRNA; pantoprazole results in increased expression of CYP1A2 protein CTD PMID:9152597 PMID:25626140 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP pantoprazole results in increased expression of CYP2B1 protein CTD PMID:9152597 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP pantoprazole results in increased expression of CYP2B2 protein CTD PMID:9152597 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects response to substance
multiple interactions
decreases activity
increases metabolic processing
ISO CYP2C19 gene polymorphism affects the susceptibility to pantoprazole
pantoprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]
pantoprazole results in decreased activity of CYP2C19 protein
CYP2C19 protein results in increased metabolism of pantoprazole
CTD PMID:8930576 PMID:15258107 PMID:20223877 PMID:21795468 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Pantoprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:36243147 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
increases metabolic processing
ISO Pantoprazole results in increased expression of CYP3A4 protein
Pantoprazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]
CYP3A4 protein results in increased metabolism of Pantoprazole
CTD PMID:8930576 PMID:9744552 PMID:15258107 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Fasn fatty acid synthase increases expression ISO Pantoprazole results in increased expression of FASN protein CTD PMID:39004236 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity ISO Pantoprazole results in increased activity of GAPDH protein CTD PMID:39004236 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO Pantoprazole results in increased expression of HAMP mRNA CTD PMID:31669099 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO pantoprazole decreases expression of JAK2 mRNA and decreases phosphorylation of JAK2 protein in gastrocnemius RGD PMID:28489606 RGD:127285673 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Pantoprazole results in increased expression of LPL mRNA; Pantoprazole results in increased expression of LPL protein CTD PMID:39004236 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP pantoprazole inhibits the reaction [Indomethacin results in increased expression of MPO protein]; pantoprazole inhibits the reaction [Ketoprofen results in increased expression of MPO protein]; pantoprazole inhibits the reaction [Piroxicam results in increased expression of MPO protein] CTD PMID:16080005 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [pantoprazole co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; pantoprazole promotes the reaction [Acetic Acid results in increased expression of PCNA protein] CTD PMID:18853145 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Pantoprazole results in increased expression of PPARG mRNA CTD PMID:39004236 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Retsat retinol saturase increases expression EXP pantoprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP pantoprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO [Pantoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Pantoprazole results in increased expression of SREBF1 mRNA; Pantoprazole results in increased expression of SREBF1 protein CTD PMID:39004236 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Pantoprazole results in increased expression of TGFB1 protein CTD PMID:36243147 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP pantoprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP pantoprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
parbendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO parbendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
pimobendan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases methylation ISO CYP1A2 protein results in decreased methylation of pimobendan CTD PMID:10611143 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation ISO CYP3A4 protein results in decreased methylation of pimobendan CTD PMID:10611143 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO pimobendan promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
pimobendan results in decreased expression of IL1B protein
CTD PMID:9004165 PMID:10193745 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
ISO pimobendan results in decreased expression of IL6 protein
pimobendan inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:9004165 PMID:10193745 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 multiple interactions EXP pimobendan promotes the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:9492047 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pimobendan results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
ISO pimobendan results in decreased expression of NOS2 mRNA
[pimobendan results in decreased expression of NOS2 protein] which results in decreased abundance of Nitric Oxide
CTD PMID:10193745 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO pimobendan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
pimobendan results in decreased expression of TNF protein
CTD PMID:9004165 PMID:10193745 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
pimozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Pimozide results in decreased expression of BCL2 mRNA CTD PMID:12130671 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP istradefylline inhibits the reaction [Pimozide results in increased expression of FOS protein]; Tropicamide promotes the reaction [Pimozide results in increased expression of FOS protein] CTD PMID:19467297 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Pimozide inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:197,474,714...197,486,789
Ensembl chr 2:197,474,714...197,486,789
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Pimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Pimozide results in decreased activity of KCNH2 protein
CTD PMID:15671647 PMID:19583963 PMID:21158687 PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Pimozide results in decreased secretion of and results in decreased glycosylation of LHB protein CTD PMID:3896764 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
JBrowse link
G Prl prolactin increases expression ISO Pimozide results in increased expression of PRL protein CTD PMID:8915564 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
rabeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain decreases expression EXP Rabeprazole results in decreased expression of C1QA mRNA CTD PMID:25626140 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Rabeprazole results in decreased expression of C1QC mRNA CTD PMID:25626140 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP Rabeprazole results in decreased expression of C4BPA mRNA CTD PMID:25626140 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Rabeprazole results in decreased expression of C4BPB mRNA CTD PMID:25626140 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
JBrowse link
G Cfi complement factor I decreases expression EXP Rabeprazole results in decreased expression of CFI mRNA CTD PMID:25626140 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
ISO
EXP
Rabeprazole results in increased expression of CYP1A1 mRNA; Rabeprazole results in increased expression of CYP1A1 protein
Rabeprazole results in decreased activity of CYP1A1 protein
CTD PMID:9041675 PMID:12623754 PMID:25626140 PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Rabeprazole results in increased expression of CYP1A2 mRNA CTD PMID:12623754 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Rabeprazole results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
affects response to substance
ISO CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]
CYP2C19 gene affects the susceptibility to Rabeprazole
CTD PMID:15903128 PMID:17377957 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole] CTD PMID:17377957 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO Rabeprazole results in increased expression of HAMP mRNA CTD PMID:31669099 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
JBrowse link
G Pomc proopiomelanocortin increases expression ISO Rabeprazole results in increased expression of POMC protein CTD PMID:16524691 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173
JBrowse link
G Retsat retinol saturase increases expression EXP Rabeprazole results in increased expression of RETSAT mRNA CTD PMID:25626140 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552
JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP Rabeprazole results in decreased expression of SERPING1 mRNA CTD PMID:25626140 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Rabeprazole promotes the reaction [SLC18A2 protein results in increased secretion of Histamine] CTD PMID:14642791 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Rabeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Rabeprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Rabeprazole results in increased expression of UGT2B1 mRNA CTD PMID:25626140 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
selumetinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l11 Bcl2-like 11 increases expression ISO AZD 6244 results in increased expression of BCL2L11 protein CTD PMID:22729845 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO AZD 6244 promotes the reaction [Calcitriol promotes the reaction [resveratrol results in increased expression of CAMP mRNA]]; AZD 6244 promotes the reaction [resveratrol promotes the reaction [Calcitriol results in increased expression of CAMP mRNA]] CTD PMID:24039193 NCBI chr 8:118,720,184...118,721,998
Ensembl chr 8:118,720,184...118,721,998
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP3 protein]]
Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP3 protein]
CTD PMID:17876044 PMID:27222248 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
ISO AZD 6244 results in increased cleavage of CASP7 protein
Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP7 protein]
CTD PMID:17876044 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
JBrowse link
G Casp8 caspase 8 multiple interactions ISO AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP8 protein]] CTD PMID:27222248 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Ccnb1 cyclin B1 decreases expression
multiple interactions
ISO AZD 6244 results in decreased expression of CCNB1 protein
Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CCNB1 protein]
CTD PMID:17876044 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO AZD 6244 results in decreased expression of and results in decreased phosphorylation of CCND1 protein; Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of and results in decreased phosphorylation of CCND1 protein] CTD PMID:17876044 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression
ISO Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CDK2 protein] CTD PMID:17876044 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
multiple interactions
ISO AZD 6244 results in decreased expression of CDK4 protein
Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CDK4 protein]
CTD PMID:17876044 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO AZD 6244 promotes the reaction [decitabine results in increased expression of CDKN1A] CTD PMID:19422044 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 multiple interactions ISO AZD 6244 inhibits the reaction [Harmine results in increased phosphorylation of CHD4 protein] CTD PMID:27805061 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:159,584,654...159,617,866
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation ISO AZD 6244 results in decreased phosphorylation of CREB1 protein CTD PMID:31790661 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Ku 0063794 co-treated with AZD 6244] results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:22415236 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases phosphorylation ISO AZD 6244 results in decreased phosphorylation of FOS protein CTD PMID:31790661 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation ISO selumetinib increases phosphorylation of JAK2 protein in colonic epithelium RGD PMID:30706361 RGD:127285668 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP3 protein]]; AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP8 protein]]; AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]]; AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased expression of TNFRSF10B protein]; AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased phosphorylation of MAPK1 protein]; AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased phosphorylation of MAPK3 protein]; AZD 6244 inhibits the reaction [KRAS protein mutant form affects the susceptibility to vemurafenib] CTD PMID:27222248 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased phosphorylation of MAPK1 protein]
AZD 6244 results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; Doxorubicin promotes the reaction [AZD 6244 results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]
AZD 6244 results in decreased phosphorylation of MAPK1 protein
CTD PMID:17876044 PMID:22415236 PMID:27222248 PMID:31790661 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased phosphorylation of MAPK3 protein]
AZD 6244 results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; Doxorubicin promotes the reaction [AZD 6244 results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]
AZD 6244 results in decreased phosphorylation of MAPK3 protein
CTD PMID:17876044 PMID:22415236 PMID:27222248 PMID:31790661 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases activity ISO AZD 6244 results in decreased activity of MMP1 protein CTD PMID:31790661 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO AZD 6244 results in decreased activity of MMP2 protein CTD PMID:31790661 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO AZD 6244 results in decreased activity of MMP9 protein CTD PMID:31790661 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
ISO Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of MYC protein] CTD PMID:17876044 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO AZD 6244 results in increased cleavage of PARP1 protein
Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of PARP1 protein]
AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]]
CTD PMID:17876044 PMID:27222248 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions
decreases phosphorylation
ISO Doxorubicin promotes the reaction [AZD 6244 results in decreased phosphorylation of RPS6KA1 protein] CTD PMID:17876044 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO AZD 6244 inhibits the reaction [flavone results in increased expression of SOCS3 mRNA]; AZD 6244 inhibits the reaction [flavone results in increased expression of SOCS3 protein] CTD PMID:23782265 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions ISO AZD 6244 inhibits the reaction [Harmine results in increased expression of UCP1 mRNA] CTD PMID:27805061 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO AZD 6244 results in decreased activity of UGT1A1 protein CTD PMID:38823552 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 decreases activity ISO AZD 6244 results in decreased activity of UGT1A4 protein CTD PMID:38823552 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO AZD 6244 results in decreased activity of UGT2B7 protein CTD PMID:38823552 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451
JBrowse link
telmisartan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO telmisartan results in decreased activity of ABCB11 protein
telmisartan inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:20829430 PMID:23956101 PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions
increases expression
ISO PPARG mutant form inhibits the reaction [telmisartan results in increased expression of ABCG1 mRNA] CTD PMID:22124178 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563
JBrowse link
G Ace angiotensin I converting enzyme decreases expression
multiple interactions
EXP Telmisartan results in decreased expression of ACE mRNA; Telmisartan results in decreased expression of ACE protein
Telmisartan inhibits the reaction [Pregabalin results in increased expression of ACE protein]
CTD PMID:19171132 PMID:25973029 PMID:29909460 PMID:31629013 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942
JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions
increases expression
decreases expression
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]
Telmisartan results in increased expression of ACE2 mRNA; Telmisartan results in increased expression of ACE2 protein
Telmisartan results in decreased expression of ACE2 mRNA; Telmisartan results in decreased expression of ACE2 protein
Telmisartan inhibits the reaction [Pregabalin results in decreased expression of ACE2 protein]
telmisartan decreases expression of mRNA in mandible of rats with periodontal disease
CTD
RGD
PMID:21381899 PMID:25973029 PMID:28656296 PMID:29909460 PMID:31629013 More... RGD:329956421 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:23060470 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity EXP telmisartan decreases enzyme activity of Trap, Acp5 in serum of rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO telmisartan results in increased expression of ADIPOQ mRNA
telmisartan results in increased expression of ADIPOQ protein
CTD PMID:19730415 PMID:20555330 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Agt angiotensinogen multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]
Telmisartan inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA]; Telmisartan inhibits the reaction [AGT protein results in decreased expression of SYP protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CRH protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FOS protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL1B protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Telmisartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of AGT protein]
telmisartan results in decreased expression of AGT mRNA; telmisartan results in decreased expression of AGT protein
CTD PMID:9533614 PMID:17620961 PMID:18487452 PMID:19171132 PMID:19289654 More... NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects binding
increases expression
multiple interactions
decreases expression
decreases expression
EXP
ISO
telmisartan binds to AGTR1 protein
telmisartan results in increased expression of AGTR1 mRNA
Telmisartan binds to and results in decreased activity of AGTR1 protein; Telmisartan inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; Telmisartan inhibits the reaction [Daunorubicin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein]
telmisartan binds to and results in decreased activity of AGTR1 protein
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]
telmisartan results in decreased expression of AGTR1A mRNA
telmisartan decreases expression of mRNA in mandible of rats with periodontal disease
CTD
RGD
PMID:8220885 PMID:9533614 PMID:9728324 PMID:17620961 PMID:19171132 More... RGD:329956421 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions ISO telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr 2:104,774,005...104,849,262
Ensembl chr 2:104,773,930...104,849,310
JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression EXP telmisartan increases expression of mRNA in mandible of rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity EXP Telmisartan results in increased activity of AHR protein CTD PMID:28728110 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Alb albumin affects expression
multiple interactions
ISO telmisartan affects the expression of ALB protein modified form
Telmisartan affects the reaction [LEPR protein affects the abundance of ALB protein]
CTD PMID:16671338 PMID:34464088 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases activity
multiple interactions
EXP telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease
Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of ALPL protein]
CTD
RGD
PMID:27269004 PMID:33364953 RGD:329956421 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 multiple interactions EXP telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of ANG2 protein] CTD PMID:23750309 NCBI chr15:26,871,842...26,889,421
Ensembl chr15:26,871,838...26,889,421
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA] CTD PMID:24831514 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA] CTD PMID:24831514 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] CTD PMID:23747572 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions
decreases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [telmisartan results in decreased expression of CACNA1G mRNA]; SB 203580 inhibits the reaction [telmisartan results in decreased expression of CACNA1G mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA] CTD PMID:19292980 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions
decreases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [telmisartan results in decreased expression of CACNA1H mRNA]; SB 203580 inhibits the reaction [telmisartan results in decreased expression of CACNA1H mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA] CTD PMID:19292980 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP3 protein]
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Telmisartan inhibits the reaction [Diatrizoate results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Iohexol results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of CASP3 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of CASP3]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]
Telmisartan results in decreased expression of CASP3 protein
CTD PMID:18565324 PMID:19452295 PMID:21620867 PMID:21819444 PMID:22750630 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP Telmisartan inhibits the reaction [arsenite results in decreased activity of CAT protein]; Telmisartan inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:23750309 PMID:26929000 PMID:34339004 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]
telmisartan results in decreased expression of CCL2 protein
CTD PMID:17922026 PMID:22124178 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases response to substance ISO telmisartan results in decreased susceptibility to CCL5 protein CTD PMID:18158351 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression EXP telmisartan results in decreased expression of CCR2 mRNA CTD PMID:17922026 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions
ISO telmisartan results in increased expression of CD36 mRNA
PPARG mutant form inhibits the reaction [telmisartan results in increased expression of CD36 mRNA]; T 0070907 inhibits the reaction [telmisartan results in increased expression of CD36 mRNA]
CTD PMID:22124178 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]] CTD PMID:19289654 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Telmisartan inhibits the reaction [AGT protein results in increased expression of CRH protein] CTD PMID:33872574 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
JBrowse link
G Crp C-reactive protein decreases expression ISO telmisartan results in decreased expression of CRP protein CTD PMID:20555330 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
JBrowse link
G Ctsk cathepsin K decreases expression EXP telmisartan decreases expression of mRNA in mandible of rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases response to substance
ISO PPARG protein promotes the reaction [telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]]; telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]
telmisartan results in decreased susceptibility to CXCL12 protein
CTD PMID:18158351 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression EXP telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression
multiple interactions
ISO
EXP
telmisartan results in decreased expression of CYBA mRNA; telmisartan results in decreased expression of CYBA protein
telmisartan inhibits the reaction [Daunorubicin results in increased expression of CYBA protein]
CTD PMID:16141465 PMID:19171132 PMID:21054405 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein]
telmisartan results in decreased expression of CYBB mRNA
Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB mRNA]; Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB protein]
Telmisartan inhibits the reaction [arsenite results in increased expression of CYBB mRNA]
CTD PMID:19171132 PMID:21381899 PMID:34339004 PMID:34464088 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA] CTD PMID:24831514 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO Telmisartan results in decreased activity of CYP2J2 protein CTD PMID:30965050 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression EXP telmisartan results in decreased expression of DDIT3 protein CTD PMID:19102871 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDN1 protein] CTD PMID:20888384 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDNRA protein] CTD PMID:20888384 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] CTD PMID:20888384 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASL protein]
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASLG protein]
CTD PMID:21620867 PMID:21819444 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 protein] CTD PMID:19706694 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Telmisartan inhibits the reaction [AGT protein results in increased expression of FOS protein] CTD PMID:33872574 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions ISO Telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; Telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] CTD PMID:23747572 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]
Telmisartan results in decreased expression of GFAP protein
CTD PMID:23747572 PMID:29909460 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of GGT1 protein] CTD PMID:23750309 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO Telmisartan inhibits the reaction [Dibutyl Phthalate results in increased expression of GJA1 protein] CTD PMID:37356649 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of GOT1 protein] CTD PMID:27269004 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of GPT protein] CTD PMID:26929000 PMID:27269004 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP Telmisartan results in decreased activity of GSR protein
Telmisartan inhibits the reaction [arsenite results in decreased activity of GSR protein]
CTD PMID:34339004 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO telmisartan results in increased expression of HGF mRNA CTD PMID:21479465 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression EXP telmisartan results in decreased expression of HSPA5 protein CTD PMID:19102871 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
JBrowse link
G Ibsp integrin-binding sialoprotein increases expression EXP telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]
telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]
telmisartan inhibits the reaction [Daunorubicin results in increased expression of ICAM1 protein]
CTD PMID:17724226 PMID:20888384 PMID:22124178 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
decreases expression
EXP telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]
Telmisartan results in increased expression of IL10 protein
telmisartan decreases expression of protein in mandible of WKY rats with periodontal disease
CTD
RGD
PMID:24831514 PMID:29909460 PMID:33364953 RGD:329956421 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Telmisartan inhibits the reaction [AGT protein results in increased expression of IL1B protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of IL1B protein]
telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease
CTD
RGD
PMID:22124178 PMID:33872574 PMID:34339004 PMID:33364953 RGD:329956421 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein]
telmisartan results in decreased expression of IL6 mRNA
Telmisartan results in decreased expression of IL6 protein
CTD PMID:19289654 PMID:21479465 PMID:22124178 PMID:29909460 PMID:34339004 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 increases expression EXP Telmisartan results in increased expression of INS1 protein CTD PMID:19171132 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Ins2 insulin 2 decreases expression ISO telmisartan results in decreased expression of INS protein CTD PMID:15892894 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO [Atorvastatin co-treated with Telmisartan] results in decreased expression of IRAK1 mRNA CTD PMID:20524934 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 decreases expression ISO telmisartan decreases expression of KCNN4 mRNA and protein in CD4-positive alpha-beta T cell RGD PMID:26502942 RGD:329955577 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275
JBrowse link
G Lepr leptin receptor multiple interactions ISO Telmisartan affects the reaction [LEPR protein affects the abundance of ALB protein]; Telmisartan affects the reaction [LEPR protein affects the expression of OCLN mRNA] CTD PMID:34464088 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases expression
ISO PPARD promotes the reaction [telmisartan results in increased expression of LIPE protein] CTD PMID:20176998 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:22124178 PMID:33872574 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
decreases phosphorylation
ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]
telmisartan results in decreased phosphorylation of MAPK14 protein
CTD PMID:19292980 PMID:22124178 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:22124178 PMID:33872574 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions ISO telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] CTD PMID:21381899 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor multiple interactions
increases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]
Telmisartan results in increased expression of MAS1 protein
Telmisartan inhibits the reaction [Pregabalin results in decreased expression of MAS1 protein]
CTD PMID:21381899 PMID:28656296 PMID:31629013 NCBI chr 1:50,428,064...50,459,537
Ensembl chr 1:50,425,257...50,500,561
JBrowse link
G Mir146a microRNA 146a multiple interactions ISO
EXP
[Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146A
telmisartan inhibits the reaction [ischemia-reperfusion injury increases expression of Mir146a miRNA in kidney]
CTD
RGD
PMID:20524934 PMID:27760486 RGD:155882556 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir146b microRNA 146b multiple interactions ISO [Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146B CTD PMID:20524934 NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947
JBrowse link
G Mir320a microRNA 320a multiple interactions EXP telmisartan inhibits the reaction [ischemia-reperfusion injury increases expression of Mir320a miRNA in kidney] RGD PMID:27760486 RGD:155882556 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
decreases expression
EXP telmisartan results in decreased expression of MMP2 protein
telmisartan decreases expression of mRNA in mandible of WKY rats with periodontal disease
CTD
RGD
PMID:21054405 PMID:33364953 RGD:329956421 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO
EXP
bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]
Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
CTD PMID:23060470 PMID:24831514 PMID:26439596 PMID:26929000 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO MYLK protein inhibits the reaction [Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]]; Telmisartan inhibits the reaction [Glucose results in increased expression of MYLK mRNA]; Telmisartan inhibits the reaction [Glucose results in increased expression of MYLK protein] CTD PMID:34464088 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]
telmisartan results in decreased expression of NCF1 mRNA; telmisartan results in decreased expression of NCF1 protein
Telmisartan results in decreased expression of NCF1 mRNA; Telmisartan results in decreased expression of NCF1 protein
telmisartan inhibits the reaction [Daunorubicin results in increased expression of NCF1 protein]
CTD PMID:16141465 PMID:19171132 PMID:21054405 PMID:21381899 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein]
telmisartan results in decreased expression of NCF2 mRNA; telmisartan results in decreased expression of NCF2 protein
telmisartan inhibits the reaction [Daunorubicin results in increased expression of NCF2 protein]
CTD PMID:16141465 PMID:21054405 PMID:21381899 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NFKB1 protein] CTD PMID:21620867 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA] CTD PMID:22124178 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of NOS2 protein]
Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of NOS2]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:21620867 PMID:21819444 PMID:22750630 PMID:24831514 PMID:26439596 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
increases phosphorylation
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in increased expression of NOS3 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in increased phosphorylation of NOS3 protein] CTD PMID:21156825 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP telmisartan inhibits the reaction [Daunorubicin results in increased expression of NOX4 protein] CTD PMID:21054405 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP Telmisartan inhibits the reaction [Daunorubicin results in decreased expression of NPHS1 protein] CTD PMID:20888384 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521
JBrowse link
G Nppb natriuretic peptide B affects expression
decreases expression
multiple interactions
ISO
EXP
telmisartan affects the expression of NPPB protein
telmisartan results in decreased expression of NPPB protein
Telmisartan inhibits the reaction [Pregabalin results in increased expression of NPPB protein]
CTD PMID:16671338 PMID:18712048 PMID:31629013 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
JBrowse link
G Ocln occludin multiple interactions ISO MYLK protein inhibits the reaction [Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]]; Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]; Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN protein]
Telmisartan affects the reaction [LEPR protein affects the expression of OCLN mRNA]
CTD PMID:34464088 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions ISO Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA]; Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein] CTD PMID:22124178 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions EXP telmisartan inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA] CTD PMID:19706694 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression
multiple interactions
EXP
ISO
telmisartan results in increased expression of PPARD protein
PPARD promotes the reaction [telmisartan results in increased expression of LIPE protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP1 protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP2 protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP3 protein]
CTD PMID:20176998 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases activity
increases expression
ISO
EXP
PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]]; PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; PPARG mutant form inhibits the reaction [telmisartan results in increased expression of ABCG1 mRNA]; PPARG mutant form inhibits the reaction [telmisartan results in increased expression of CD36 mRNA]; PPARG protein promotes the reaction [telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]]
Telmisartan results in increased activity of PPARG protein
telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]
telmisartan results in increased expression of PPARG protein
telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; telmisartan promotes the reaction [Daunorubicin results in increased expression of PPARG protein]
CTD PMID:18158351 PMID:20176998 PMID:20888384 PMID:21381899 PMID:22124178 More... NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] CTD PMID:21381899 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO Telmisartan inhibits the reaction [Dibutyl Phthalate results in increased expression of PRKAA2 protein] CTD PMID:37356649 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP Telmisartan inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein] CTD PMID:31629013 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases activity
ISO
EXP
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
[Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [arsenite results in increased activity of PTGS2 protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Daunorubicin results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of PTGS2]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]
telmisartan inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein]
Telmisartan results in increased activity of PTGS2 protein
CTD PMID:20223228 PMID:20888384 PMID:22124178 PMID:22750630 PMID:24831514 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions EXP telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTH1R protein] CTD PMID:23750309 NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108
JBrowse link
G Pthlh parathyroid hormone-like hormone multiple interactions EXP telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTHLH protein] CTD PMID:23750309 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]
telmisartan inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
CTD PMID:20223228 PMID:22124178 PMID:24831514 PMID:26929000 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Ren renin increases expression EXP telmisartan results in increased expression of REN mRNA; telmisartan results in increased expression of REN protein CTD PMID:9533614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP telmisartan increases expression of mRNA in mandible of rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 increases activity ISO telmisartan results in increased activity of SCN5A protein CTD PMID:29306026 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470
JBrowse link
G Sema3b semaphorin 3B multiple interactions ISO telmisartan inhibits the reaction [Calcitriol results in increased expression of SEMA3B protein]; telmisartan inhibits the reaction [Progesterone results in increased expression of SEMA3B protein] CTD PMID:21933904 NCBI chr 8:117,150,307...117,161,570
Ensembl chr 8:117,150,589...117,157,658
JBrowse link
G Sema3f semaphorin 3F multiple interactions ISO telmisartan inhibits the reaction [Calcitriol results in increased expression of SEMA3F protein]; telmisartan inhibits the reaction [Progesterone results in increased expression of SEMA3F protein] CTD PMID:21933904 NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO
EXP
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA]
telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]
CTD PMID:17620961 PMID:19706694 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] CTD PMID:23747572 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO telmisartan inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] CTD PMID:23747572 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962
JBrowse link
G Snca synuclein alpha multiple interactions ISO telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein] CTD PMID:23747572 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Telmisartan inhibits the reaction [Methotrexate results in decreased expression of and results in decreased activity of SOD1 protein] CTD PMID:27269004 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
JBrowse link
G Syp synaptophysin multiple interactions ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]
telmisartan inhibits the reaction [AGT protein results in decreased expression of SYP protein]; telmisartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein]
CTD PMID:18487452 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:17,521,348...17,536,984
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]
telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; telmisartan inhibits the reaction [Daunorubicin results in increased expression of TGFB1 protein]
telmisartan results in decreased expression of TGFB1 mRNA
CTD PMID:19171132 PMID:19706694 PMID:20888384 PMID:21381899 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23747572 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
affects localization
decreases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan affects the localization of TJP1 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]; wortmannin inhibits the reaction [telmisartan affects the localization of TJP1 protein]; wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]; wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]
telmisartan results in decreased expression of TJP1 mRNA; telmisartan results in decreased expression of TJP1 protein
CTD PMID:19252288 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 protein CTD PMID:20524934 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases expression
ISO
EXP
PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; T 0070907 inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; T 0070907 inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of TNF]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of TNF]; Telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein]
Telmisartan results in decreased expression of TNF protein
telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease
CTD
RGD
PMID:19289654 PMID:20223228 PMID:21620867 PMID:21819444 PMID:22124178 More... RGD:329956421 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression EXP telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression EXP telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO [Atorvastatin co-treated with Telmisartan] results in decreased expression of TRAF6 mRNA CTD PMID:20524934 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions
increases expression
ISO PPARD promotes the reaction [telmisartan results in increased expression of UCP1 protein] CTD PMID:20176998 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression
ISO PPARD promotes the reaction [telmisartan results in increased expression of UCP2 protein] CTD PMID:20176998 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions
increases expression
ISO PPARD promotes the reaction [telmisartan results in increased expression of UCP3 protein] CTD PMID:20176998 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP telmisartan inhibits the reaction [Daunorubicin results in increased expression of VCAM1 protein] CTD PMID:20888384 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]
telmisartan results in decreased expression of VEGFA mRNA
telmisartan inhibits the reaction [sodium arsenite results in increased expression of VEGFA]
CTD PMID:17724226 PMID:19171132 PMID:26439596 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Vtn vitronectin decreases expression EXP telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease RGD PMID:33364953 RGD:329956421 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860
JBrowse link
thiabendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700012B07Rikl RIKEN cDNA 1700012B07 gene like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of 1700012B07RIKL gene CTD PMID:33854195 NCBI chr10:95,271,034...95,304,337
Ensembl chr10:95,268,422...95,304,315
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Thiabendazole results in decreased expression of ABCB1 mRNA CTD PMID:39207506 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Thiabendazole results in increased expression of ABCC2 mRNA CTD PMID:39207506 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ACOT2 gene CTD PMID:33854195 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502
JBrowse link
G Acot4 acyl-CoA thioesterase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACOT4 mRNA CTD PMID:33854195 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
JBrowse link
G Acy1 aminoacylase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACY1 mRNA CTD PMID:33854195 NCBI chr 8:115,951,068...115,956,471
Ensembl chr 8:115,951,068...115,956,405
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAM15 gene CTD PMID:33854195 NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
JBrowse link
G Adamtsl3 ADAMTS-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAMTSL3 gene CTD PMID:33854195 NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:145,698,004...146,006,195
JBrowse link
G Adcy6 adenylate cyclase 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ADCY6 mRNA CTD PMID:33854195 NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770
JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ADRM1 mRNA CTD PMID:33854195 NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AFP mRNA CTD PMID:33854195 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
JBrowse link
G Agt angiotensinogen multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AGT mRNA CTD PMID:33854195 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Aig1 androgen-induced 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of AIG1 gene CTD PMID:33854195 NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155
JBrowse link
G Akap8 A-kinase anchoring protein 8 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8 mRNA CTD PMID:33854195 NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900
JBrowse link
G Akap8l A-kinase anchoring protein 8 like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8L mRNA CTD PMID:33854195 NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811
JBrowse link
G Alb albumin decreases expression EXP Thiabendazole results in decreased expression of ALB mRNA CTD PMID:18539377 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALDH9A1 mRNA CTD PMID:33854195 NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALG2 mRNA CTD PMID:33854195 NCBI chr 5:66,564,328...66,568,887
Ensembl chr 5:66,564,330...66,568,887
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions
increases expression
EXP
ISO
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANGPTL4 mRNA
Thiabendazole results in increased expression of ANGPTL4 mRNA
CTD PMID:33854195 PMID:39207506 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
JBrowse link
G Anks3 ankyrin repeat and sterile alpha motif domain containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ANKS3 mRNA CTD PMID:33854195 NCBI chr10:11,121,504...11,142,261
Ensembl chr10:11,121,553...11,142,491
JBrowse link
G Anxa11 annexin A11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANXA11 mRNA CTD PMID:33854195 NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839
JBrowse link
G Aplf aprataxin and PNKP like factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APLF mRNA CTD PMID:33854195 NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961
JBrowse link
G Apof apolipoprotein F multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APOF mRNA CTD PMID:33854195 NCBI chr 7:1,285,222...1,286,659
Ensembl chr 7:1,285,222...1,286,659
JBrowse link
G Arf2 ADP-ribosylation factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ARF2 mRNA CTD PMID:33854195 NCBI chr10:89,367,843...89,389,644
Ensembl chr10:89,368,044...89,389,651
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ARPC1A gene CTD PMID:33854195 NCBI chr12:14,616,245...14,639,052
Ensembl chr12:14,616,248...14,639,052
JBrowse link
G Asb7 ankyrin repeat and SOCS box-containing 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ASB7 mRNA CTD PMID:33854195 NCBI chr 1:129,621,462...129,677,788
Ensembl chr 1:129,635,330...129,677,505
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ASS1 mRNA CTD PMID:33854195 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627
JBrowse link
G Atosa atos homolog A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA CTD PMID:33854195 NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP5MC1 mRNA CTD PMID:33854195 NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP6V0D1 mRNA CTD PMID:33854195 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BAG3 mRNA CTD PMID:33854195 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
JBrowse link
G Banp Btg3 associated nuclear protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BANP mRNA CTD PMID:33854195 NCBI chr19:66,916,417...66,994,286
Ensembl chr19:66,916,267...66,991,317
JBrowse link
G Bcl9 BCL9, transcription coactivator multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of BCL9 mRNA CTD PMID:33854195 NCBI chr 2:187,449,425...187,475,241
Ensembl chr 2:187,449,425...187,475,241
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BHMT mRNA CTD PMID:33854195 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715
JBrowse link
G C1qc complement C1q C chain multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C1QC mRNA CTD PMID:33854195 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
JBrowse link
G C8h11orf54 similar to human chromosome 11 open reading frame 54 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C8H11ORF54 mRNA CTD PMID:33854195 NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAMK2G mRNA CTD PMID:33854195 NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CAP1 mRNA CTD PMID:33854195 NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470
JBrowse link
G Caps2 calcyphosine 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAPS2 mRNA CTD PMID:33854195 NCBI chr 7:49,467,320...49,525,465
Ensembl chr 7:49,464,885...49,525,465
JBrowse link
G Casp3 caspase 3 increases activity EXP Thiabendazole results in increased activity of CASP3 protein CTD PMID:26748015 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases activity EXP Thiabendazole results in increased activity of CASP8 protein CTD PMID:26748015 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases activity EXP Thiabendazole results in increased activity of CASP9 protein CTD PMID:26748015 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cbs cystathionine beta synthase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CBS mRNA CTD PMID:33854195 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066
JBrowse link
G Ccdc125 coiled-coil domain containing 125 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCDC125 mRNA CTD PMID:33854195 NCBI chr 2:33,542,916...33,568,501
Ensembl chr 2:33,543,300...33,568,288
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Thiabendazole results in increased expression of CCND1 mRNA CTD PMID:39207506 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccnl1 cyclin L1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA CTD PMID:33854195 NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
EXP
ISO
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA
Thiabendazole results in increased expression of CDKN1A mRNA
CTD PMID:33854195 PMID:39207506 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CEBPD mRNA CTD PMID:33854195 NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824
JBrowse link
G Cep85 centrosomal protein 85 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CEP85 mRNA CTD PMID:33854195 NCBI chr 5:151,640,316...151,687,891
Ensembl chr 5:151,639,282...151,687,860
JBrowse link
G Cerk ceramide kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CERK mRNA CTD PMID:33854195 NCBI chr 7:119,105,674...119,149,885
Ensembl chr 7:119,105,674...119,148,570
JBrowse link
G Cfb complement factor B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFB mRNA CTD PMID:33854195 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
JBrowse link
G Cfl1 cofilin 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFL1 mRNA CTD PMID:33854195 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CHCHD10 mRNA CTD PMID:33854195 NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,277...12,745,677
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CHEK2 mRNA CTD PMID:33854195 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
JBrowse link
G Chmp5 charged multivesicular body protein 5 affects expression EXP Thiabendazole affects the expression of CHMP5 mRNA CTD PMID:18539377 NCBI chr 5:60,877,369...60,894,512
Ensembl chr 5:60,877,341...60,894,511
JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CIRBP mRNA CTD PMID:33854195 NCBI chr 7:10,184,515...10,189,623 JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLCF1 mRNA CTD PMID:33854195 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064
JBrowse link
G Clec2g C-type lectin domain family 2, member G multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLEC2G mRNA CTD PMID:33854195 NCBI chr 4:164,303,865...164,313,737
Ensembl chr 4:164,300,076...164,314,591
JBrowse link
G Clu clusterin multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CLU mRNA CTD PMID:33854195 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CNDP2 mRNA CTD PMID:33854195 NCBI chr18:80,314,799...80,331,900
Ensembl chr18:80,314,801...80,331,900
JBrowse link
G Cp ceruloplasmin decreases expression ISO Thiabendazole results in decreased expression of CP mRNA CTD PMID:39207506 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CPT2 mRNA CTD PMID:33854195 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818
JBrowse link
G Cry1 cryptochrome circadian regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CRY1 mRNA CTD PMID:33854195 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822
JBrowse link
G Cryab crystallin, alpha B decreases expression ISO Thiabendazole results in decreased expression of CRYAB mRNA CTD PMID:39207506 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
JBrowse link
G Cspp1 centrosome and spindle pole associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSPP1 mRNA CTD PMID:33854195 NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSRNP1 mRNA CTD PMID:33854195 NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of CTH gene CTD PMID:33854195 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CTNNAL1 mRNA CTD PMID:33854195 NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637
JBrowse link
G Cux2 cut-like homeobox 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CUX2 mRNA CTD PMID:33854195 NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
EXP
ISO
herbimycin inhibits the reaction [Thiabendazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Thiabendazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Thiabendazole results in increased expression of CYP1A1 protein]
Thiabendazole results in increased expression of CYP1A1 mRNA; Thiabendazole results in increased expression of CYP1A1 protein
CTD PMID:8900397 PMID:10103034 PMID:11226373 PMID:14987951 PMID:15110098 More... NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
affects metabolic processing
decreases activity
ISO
EXP
beta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]
Thiabendazole results in increased expression of CYP1A2 mRNA; Thiabendazole results in increased expression of CYP1A2 protein
Thiabendazole results in decreased activity of CYP1A2 protein
CTD PMID:10936227 PMID:11124226 PMID:12920490 PMID:15110098 PMID:16261361 More... NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Thiabendazole results in increased expression of CYP2B1 mRNA; Thiabendazole results in increased expression of CYP2B1 protein CTD PMID:15110098 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Thiabendazole results in increased expression of CYP2B2 mRNA; Thiabendazole results in increased expression of CYP2B2 protein CTD PMID:15110098 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Thiabendazole results in increased expression of CYP2B6 mRNA CTD PMID:18570159 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP2C22 mRNA CTD PMID:33854195 NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression ISO Thiabendazole results in increased expression of CYP2C19 mRNA CTD PMID:39207506 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Thiabendazole results in decreased expression of CYP2E1 mRNA CTD PMID:39207506 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Thiabendazole results in increased expression of CYP3A4 mRNA CTD PMID:18570159 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4A1 mRNA CTD PMID:33854195 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4F1 mRNA CTD PMID:33854195 NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612
JBrowse link
G Cytip cytohesin 1 interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CYTIP mRNA CTD PMID:33854195 NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DBP mRNA CTD PMID:33854195 NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
JBrowse link
G Dclre1c DNA cross-link repair 1C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DCLRE1C mRNA CTD PMID:33854195 NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734
JBrowse link
G Ddx20 DEAD-box helicase 20 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX20 mRNA CTD PMID:33854195 NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:195,847,105...195,855,461
JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX5 mRNA CTD PMID:33854195 NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300
JBrowse link
G Defb1 defensin beta 1 decreases expression ISO Thiabendazole results in decreased expression of DEFB1 mRNA CTD PMID:39207506 NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068
JBrowse link
G Dffb DNA fragmentation factor subunit beta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DFFB mRNA CTD PMID:33854195 NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DLG2 gene CTD PMID:33854195 NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DLL1 mRNA CTD PMID:33854195 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DMRT3 gene CTD PMID:33854195 NCBI chr 1:232,670,642...232,690,557
Ensembl chr 1:232,675,059...232,688,833
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB1 mRNA CTD PMID:33854195 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB9 mRNA CTD PMID:33854195 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DPP4 mRNA CTD PMID:33854195 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP1 mRNA CTD PMID:33854195 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DUSP5 gene CTD PMID:33854195 NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP6 mRNA CTD PMID:33854195 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
JBrowse link
G Dzip1l DAZ interacting zinc finger protein 1-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DZIP1L gene CTD PMID:33854195 NCBI chr 8:109,067,466...109,108,390
Ensembl chr 8:109,067,775...109,108,393
JBrowse link
G Emilin1 elastin microfibril interfacer 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of EMILIN1 mRNA CTD PMID:33854195 NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657
JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ENPP3 mRNA CTD PMID:33854195 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of EPB41L3 gene CTD PMID:33854195 NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274
JBrowse link
G Epm2aip1 EPM2A interacting protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of EPM2AIP1 mRNA CTD PMID:33854195 NCBI chr 8:120,112,265...120,119,613
Ensembl chr 8:120,112,084...120,121,458
JBrowse link
G Erf Ets2 repressor factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ERF mRNA CTD PMID:33854195 NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213
JBrowse link
G Esd esterase D multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ESD mRNA CTD PMID:33854195 NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
JBrowse link
G Fam135a family with sequence similarity 135, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA CTD PMID:33854195 NCBI chr 9:33,916,449...33,997,140
Ensembl chr 9:33,916,449...33,997,051
JBrowse link
G Fam177a1 family with sequence similarity 177, member A1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM177A1 gene CTD PMID:33854195 NCBI chr 6:78,367,780...78,382,703
Ensembl chr 6:78,367,780...78,392,836
JBrowse link
G Fam204a family with sequence similarity 204, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM204A mRNA CTD PMID:33854195 NCBI chr 1:269,323,473...269,352,772
Ensembl chr 1:269,323,473...269,352,772
JBrowse link
G Fam53a family with sequence similarity 53, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM53A gene CTD PMID:33854195 NCBI chr14:81,308,127...81,348,930
Ensembl chr14:81,319,375...81,348,923
JBrowse link
G Ficd FIC domain protein adenylyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FICD mRNA CTD PMID:33854195 NCBI chr12:48,549,737...48,554,626
Ensembl chr12:48,549,737...48,554,626
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FKBP4 mRNA CTD PMID:33854195 NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of FKBP5 gene CTD PMID:33854195 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
JBrowse link
G Fmn1 formin 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FMN1 mRNA CTD PMID:33854195 NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO Thiabendazole results in decreased expression of FMO2 mRNA CTD PMID:39207506 NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534
JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FRMD4B mRNA CTD PMID:33854195 NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287
JBrowse link
G Fzd6 frizzled class receptor 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FZD6 mRNA CTD PMID:33854195 NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Thiabendazole results in increased expression of GADD45A mRNA CTD PMID:18539377 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GADD45G mRNA CTD PMID:33854195 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369
JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GATD3A mRNA CTD PMID:33854195 NCBI chr20:10,514,459...10,522,556
Ensembl chr20:10,514,443...10,522,555
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
multiple interactions
ISO Thiabendazole results in increased activity of GCLC protein
[Thiabendazole co-treated with Buthionine Sulfoximine] results in increased activity of GCLC protein
CTD PMID:11019651 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
JBrowse link
G Ghr growth hormone receptor increases expression ISO Thiabendazole results in increased expression of GHR mRNA CTD PMID:39207506 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
JBrowse link
G Gin1 gypsy retrotransposon integrase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIN1 mRNA CTD PMID:33854195 NCBI chr 9:105,740,914...105,762,357
Ensembl chr 9:105,742,094...105,762,357
JBrowse link
G Git2 GIT ArfGAP 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIT2 mRNA CTD PMID:33854195 NCBI chr12:47,490,350...47,531,232
Ensembl chr12:47,490,369...47,533,250
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GLB1 mRNA CTD PMID:33854195 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GNPDA2 mRNA CTD PMID:33854195 NCBI chr14:38,874,611...38,892,688
Ensembl chr14:38,874,647...38,892,683
JBrowse link
G Gprasp3 G protein-coupled receptor associated sorting protein family member 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA CTD PMID:33854195 NCBI chr  X:103,639,366...103,644,561
Ensembl chr  X:103,609,243...103,650,463
JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GRAMD1A mRNA CTD PMID:33854195 NCBI chr 1:95,494,378...95,520,730
Ensembl chr 1:95,494,378...95,520,716
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GRIA1 gene CTD PMID:33854195 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GRINA mRNA CTD PMID:33854195 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
JBrowse link
G Gsdma gasdermin A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GSDMA gene CTD PMID:33854195 NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GSTK1 mRNA CTD PMID:33854195 NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Thiabendazole results in increased expression of GSTP1 mRNA CTD PMID:15110098 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Thiabendazole results in increased expression of GSTT1 mRNA CTD PMID:15110098 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
JBrowse link
G Hapstr2 HUWE1 associated protein modifying stress responses 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of HAPSTR2 gene CTD PMID:33854195 NCBI chr  X:143,958,364...143,960,399
Ensembl chr  X:143,958,032...143,960,240
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HARS1 mRNA CTD PMID:33854195 NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression ISO Thiabendazole results in decreased expression of HAVCR1 mRNA CTD PMID:39207506 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
JBrowse link
G Hebp1 heme binding protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HEBP1 mRNA CTD PMID:33854195 NCBI chr 4:169,705,665...169,735,199
Ensembl chr 4:169,705,668...169,735,199
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HES1 mRNA CTD PMID:33854195 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Thiabendazole results in increased expression of HMOX1 mRNA CTD PMID:39207506 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HS3ST3B1 mRNA CTD PMID:33854195 NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD17B10 mRNA CTD PMID:33854195 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:24,568,551...24,574,681
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HSD17B2 mRNA CTD PMID:33854195 NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPA1B mRNA CTD PMID:33854195 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPBP1 mRNA CTD PMID:33854195 NCBI chr 1:78,194,067...78,217,836
Ensembl chr 1:78,189,305...78,217,835
JBrowse link
G Ier3 immediate early response 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IER3 mRNA CTD PMID:33854195 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
JBrowse link
G Ifna12l interferon alpha 12 like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IFNA12L gene CTD PMID:33854195 NCBI chr 5:108,592,149...108,593,214
Ensembl chr 5:108,541,882...108,571,940
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions
increases expression
EXP
ISO
[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IGFBP1 mRNA
Thiabendazole results in increased expression of IGFBP1 mRNA
CTD PMID:33854195 PMID:39207506 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
JBrowse link
G Igkv2-112l2 immunoglobulin kappa variable 2-112 like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IGKV2-112L2 gene CTD PMID:33854195 NCBI chr 4:103,444,658...103,445,307
Ensembl chr 4:103,766,891...103,767,229
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of INPP5F mRNA CTD PMID:33854195 NCBI chr 1:192,620,891...192,700,681
Ensembl chr 1:192,620,891...192,700,681
JBrowse link
G Iqcb1 IQ motif containing B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IQCB1 mRNA CTD PMID:33854195 NCBI chr11:77,410,986...77,465,540
Ensembl chr11:77,410,314...77,465,478
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IRF2BP2 mRNA CTD PMID:33854195 NCBI chr19:71,456,689...71,462,368
Ensembl chr19:71,456,689...71,462,368
JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ITPRIP mRNA CTD PMID:33854195 NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:256,699,832...256,727,644
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of JUNB mRNA CTD PMID:33854195 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
JBrowse link
G Katnip katanin interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KATNIP gene CTD PMID:33854195 NCBI chr 1:189,700,838...189,867,402
Ensembl chr 1:189,700,775...189,867,402
JBrowse link
G Khdc4 KH domain containing 4, pre-mRNA splicing factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KHDC4 mRNA CTD PMID:33854195 NCBI chr 2:176,446,895...176,475,405
Ensembl chr 2:176,446,910...176,475,392
JBrowse link
G Klf10 KLF transcription factor 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KLF10 mRNA CTD PMID:33854195 NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of KLF2 mRNA CTD PMID:33854195 NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768
JBrowse link
G Klhl10 kelch-like family member 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KLHL10 gene CTD PMID:33854195 NCBI chr10:85,876,804...85,893,081
Ensembl chr10:85,876,783...85,893,081
JBrowse link
G Lgalsl galectin-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LGALSL mRNA CTD PMID:33854195 NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487
JBrowse link
G Lhx2 LIM homeobox 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of LHX2 gene CTD PMID:33854195 NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LITAF mRNA CTD PMID:33854195 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
JBrowse link
G Lnx2 ligand of numb-protein X 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LNX2 mRNA CTD PMID:33854195 NCBI chr12:13,119,139...13,184,401
Ensembl chr12:13,119,139...13,184,401
JBrowse link
G Loxl3 lysyl oxidase-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LOXL3 gene CTD PMID:33854195 NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046
JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPCAT1 gene CTD PMID:33854195 NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:31,594,622...31,644,946
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPGAT1 gene CTD PMID:33854195 NCBI chr13:105,825,630...105,896,366
Ensembl chr13:105,820,468...105,896,364
JBrowse link
G Lpin3 lipin 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LPIN3 mRNA CTD PMID:33854195 NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:169,960,522...169,978,031
JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LTA4H mRNA CTD PMID:33854195 NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LURAP1L gene CTD PMID:33854195 NCBI chr 5:100,402,921...100,455,479
Ensembl chr 5:100,407,483...100,455,478
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Thiabendazole results in increased expression of MAP1LC3B protein CTD PMID:39207506 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MAPKAPK2 mRNA CTD PMID:33854195 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326
JBrowse link
G Marf1 meiosis regulator and mRNA stability factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MARF1 mRNA CTD PMID:33854195 NCBI chr10:1,395,271...1,439,974
Ensembl chr10:1,395,282...1,439,974
JBrowse link
G Med12l mediator complex subunit 12L multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MED12L mRNA CTD PMID:33854195 NCBI chr 2:145,403,318...145,726,317
Ensembl chr 2:145,404,375...145,723,516
JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of METTL14 mRNA CTD PMID:33854195 NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:214,215,165...214,231,412
JBrowse link
G Mfap5 microfibril associated protein 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of MFAP5 gene CTD PMID:33854195 NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:157,395,597...157,422,448
JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIF mRNA CTD PMID:33854195 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121
JBrowse link
G Mir122 microRNA 122 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR122 mRNA CTD PMID:34626815 NCBI chr18:61,028,817...61,028,901 JBrowse link
G Mir130a microRNA 130a multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR130A mRNA CTD PMID:34626815 NCBI chr 3:90,229,228...90,229,315 JBrowse link
G Mir146a microRNA 146a multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR146A mRNA CTD PMID:34626815 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir193 microRNA 193 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR193 mRNA CTD PMID:34626815 NCBI chr10:65,170,317...65,170,402 JBrowse link
G Mir22 microRNA 22 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR22 mRNA CTD PMID:34626815 NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425
JBrowse link
G Mir32 microRNA 32 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR32 mRNA CTD PMID:34626815 NCBI chr 5:76,391,285...76,391,354 JBrowse link
G Mir33 microRNA 33 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR33 mRNA CTD PMID:34626815 NCBI chr 7:115,593,952...115,594,020
Ensembl chr 7:115,593,952...115,594,020
JBrowse link
G Mir486 microRNA 486 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR486 mRNA CTD PMID:34626815
G Mlycd malonyl-CoA decarboxylase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MLYCD mRNA CTD PMID:33854195 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MOCS2 mRNA CTD PMID:33854195 NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394
JBrowse link
G Morc3 MORC family CW-type zinc finger 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MORC3 mRNA CTD PMID:33854195 NCBI chr11:46,621,575...46,664,315
Ensembl chr11:46,621,548...46,664,309
JBrowse link
G Mpo myeloperoxidase increases metabolic processing ISO MPO protein results in increased metabolism of Thiabendazole metabolite CTD PMID:21513789 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mrgbp MRG domain binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRGBP mRNA CTD PMID:33854195 NCBI chr 3:188,074,695...188,078,162
Ensembl chr 3:188,074,709...188,078,153
JBrowse link
G Mrnip MRN complex interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRNIP mRNA CTD PMID:33854195 NCBI chr10:35,002,440...35,026,555 JBrowse link
G Mrpl44 mitochondrial ribosomal protein L44 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPL44 mRNA CTD PMID:33854195 NCBI chr 9:88,555,050...88,560,101
Ensembl chr 9:88,555,019...88,561,215
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPS18B mRNA CTD PMID:33854195 NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MTARC1 mRNA CTD PMID:33854195 NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252
JBrowse link
G Myo10 myosin X multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MYO10 mRNA CTD PMID:33854195 NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:77,831,532...78,036,137
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of N4BP2L2 mRNA CTD PMID:33854195 NCBI chr12:4,972,967...5,038,027
Ensembl chr12:4,972,990...5,033,405
JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NAE1 mRNA CTD PMID:33854195 NCBI chr19:452,462...478,591
Ensembl chr19:452,432...478,831
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of NDUFB11 gene CTD PMID:33854195 NCBI chr  X:4,126,317...4,128,575
Ensembl chr  X:4,126,245...4,128,566
JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NFE2 mRNA CTD PMID:33854195 NCBI chr 7:136,261,234...136,273,850
Ensembl chr 7:136,261,236...136,268,585
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NFIL3 mRNA CTD PMID:33854195 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826
JBrowse link
G Nppb natriuretic peptide B increases expression EXP Thiabendazole results in increased expression of NPPB mRNA CTD PMID:18539377 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR0B2 mRNA CTD PMID:33854195 NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D1 mRNA CTD PMID:33854195 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D2 mRNA CTD PMID:33854195 NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Thiabendazole results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NUCKS1 mRNA CTD PMID:33854195 NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO Thiabendazole results in increased expression of ODC1 mRNA CTD PMID:39207506 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
JBrowse link
G Olr943 olfactory receptor 943 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of OLR943 gene CTD PMID:33854195 NCBI chr 7:4,038,349...4,039,287
Ensembl chr 7:4,038,349...4,039,287
JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of OPLAH mRNA CTD PMID:33854195 NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:109,891,405...109,915,979
JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ORAI3 gene CTD PMID:33854195 NCBI chr 1:191,811,671...191,816,530
Ensembl chr 1:191,811,424...191,816,530
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 affects expression EXP Thiabendazole affects the expression of OXCT1 mRNA CTD PMID:18539377 NCBI chr 2:54,963,964...55,112,303
Ensembl chr 2:54,963,784...55,112,298
JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PABIR1 gene CTD PMID:33854195 NCBI chr 1:231,541,411...231,542,717
Ensembl chr 1:231,537,357...231,612,411
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Thiabendazole results in increased cleavage of PARP1 protein CTD PMID:39207506 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Parpbp PARP1 binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of PARPBP gene CTD PMID:33854195 NCBI chr 7:24,398,897...24,468,330
Ensembl chr 7:24,398,897...24,464,744
JBrowse link
G Pdlim1 PDZ and LIM domain 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PDLIM1 mRNA CTD PMID:33854195 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379
JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PDP1 mRNA CTD PMID:33854195 NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960
JBrowse link
G Pdzd2 PDZ domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PDZD2 gene CTD PMID:33854195 NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478
JBrowse link
G Per1 period circadian regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PER1 mRNA CTD PMID:33854195 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
JBrowse link
G Per3 period circadian regulator 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PER3 mRNA CTD PMID:33854195 NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP Thiabendazole results in increased expression of PFKFB1 mRNA CTD PMID:18539377 NCBI chr  X:22,936,038...22,989,691
Ensembl chr  X:22,937,494...22,989,704
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PGK1 mRNA CTD PMID:33854195 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:75,336,687...75,352,959
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIAS3 mRNA CTD PMID:33854195 NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:186,921,428...186,936,714
JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA CTD PMID:33854195 NCBI chr15:26,620,399...26,624,369
Ensembl chr15:26,620,401...26,624,246
JBrowse link
G Pirb paired Ig-like receptor B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LILRB3 mRNA CTD PMID:33854195 NCBI chr 1:74,414,556...74,433,015
Ensembl chr 1:74,331,291...74,422,116
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLEKHG5 mRNA CTD PMID:33854195 NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229
JBrowse link
G Plk2 polo-like kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLK2 mRNA CTD PMID:33854195 NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
JBrowse link
G Plpp4 phospholipid phosphatase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PLPP4 gene CTD PMID:33854195 NCBI chr 1:193,260,181...193,389,659
Ensembl chr 1:193,260,434...193,389,675
JBrowse link
G Pmvk phosphomevalonate kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PMVK mRNA CTD PMID:33854195 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNKD mRNA CTD PMID:33854195 NCBI chr 9:83,317,757...83,386,263
Ensembl chr 9:83,317,738...83,386,262
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNRC1 mRNA CTD PMID:33854195 NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of POR gene CTD PMID:33854195 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PPARD mRNA CTD PMID:33854195 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707
JBrowse link
G Prdm15 PR/SET domain 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRDM15 mRNA CTD PMID:33854195 NCBI chr11:50,633,973...50,691,624
Ensembl chr11:50,633,973...50,691,823
JBrowse link
G Prelid2 PRELI domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELID2 mRNA CTD PMID:33854195 NCBI chr18:34,120,989...34,212,699
Ensembl chr18:34,125,373...34,212,167
JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELP mRNA CTD PMID:33854195 NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
JBrowse link
G Prkcb protein kinase C, beta increases expression EXP Thiabendazole results in increased expression of PRKCB mRNA CTD PMID:18539377 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
JBrowse link
G Proser2 proline and serine rich 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PROSER2 mRNA CTD PMID:33854195 NCBI chr17:77,061,371...77,096,788
Ensembl chr17:77,077,727...77,095,194
JBrowse link
G Prpf39 pre-mRNA processing factor 39 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA CTD PMID:33854195 NCBI chr 6:88,825,227...88,851,342
Ensembl chr 6:88,825,243...88,851,341
JBrowse link
G Prss3b protease, serine, 3B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PRSS3B gene CTD PMID:33854195 NCBI chr 4:70,838,484...70,842,192
Ensembl chr 4:70,838,471...70,845,283
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC2 mRNA CTD PMID:33854195 NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC5 mRNA CTD PMID:33854195 NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PTPA mRNA CTD PMID:33854195 NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:34,087,575...34,162,772
JBrowse link
G Pus10 pseudouridine synthase 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PUS10 mRNA CTD PMID:33854195 NCBI chr14:101,822,525...101,885,187
Ensembl chr14:101,822,458...101,885,190
JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA CTD PMID:33854195 NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177
JBrowse link
G Rabl2 RAB, member of RAS oncogene family like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABL2 mRNA CTD PMID:33854195 NCBI chr 7:122,531,787...122,540,500
Ensembl chr 7:122,531,792...122,540,395
JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RAMAC gene CTD PMID:33854195 NCBI chr 1:145,117,752...145,123,640
Ensembl chr 1:145,117,736...145,124,256
JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RANGAP1 mRNA CTD PMID:33854195 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564
JBrowse link
G Rars1 arginyl-tRNA synthetase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RARS1 mRNA CTD PMID:33854195 NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,774,805...20,799,251
JBrowse link
G Rbm14 RNA binding motif protein 14 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RBM14 mRNA CTD PMID:33854195 NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:211,523,972...211,535,065
JBrowse link
G Rbm3 RNA binding motif protein 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RBM3 mRNA CTD PMID:33854195 NCBI chr  X:17,020,863...17,024,341
Ensembl chr  X:17,020,864...17,024,841
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RBPMS gene CTD PMID:33854195 NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503
JBrowse link
G Resf1 retroelement silencing factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RESF1 mRNA CTD PMID:33854195 NCBI chr 4:184,057,165...184,093,374
Ensembl chr 4:184,057,010...184,098,429
JBrowse link
G Rev1 REV1, DNA directed polymerase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of REV1 mRNA CTD PMID:33854195 NCBI chr 9:47,773,907...47,847,554
Ensembl chr 9:47,773,907...47,847,332
JBrowse link
G Rfx7 regulatory factor X, 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RFX7 mRNA CTD PMID:33854195 NCBI chr 8:82,134,747...82,219,898
Ensembl chr 8:82,134,747...82,219,898
JBrowse link
G Rgcc regulator of cell cycle multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RGCC gene CTD PMID:33854195 NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
JBrowse link
G Rgs16 regulator of G-protein signaling 16 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RGS16 mRNA CTD PMID:33854195 NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313
JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RHOBTB3 mRNA CTD PMID:33854195 NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906
JBrowse link
G Rnase10 ribonuclease A family member 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RNASE10 gene CTD PMID:33854195 NCBI chr15:26,700,219...26,702,681
Ensembl chr15:26,688,102...26,706,105
JBrowse link
G Rnd3 Rho family GTPase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RND3 gene; [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RND3 mRNA CTD PMID:33854195 NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:55,980,355...55,998,536
JBrowse link
G Rorc RAR-related orphan receptor C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RORC mRNA CTD PMID:33854195 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566
JBrowse link
G Rxylt1 ribitol xylosyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RXYLT1 gene CTD PMID:33854195 NCBI chr 7:59,656,274...59,668,140
Ensembl chr 7:59,656,276...59,668,050
JBrowse link
G Sall4 spalt-like transcription factor 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SALL4 gene CTD PMID:33854195 NCBI chr 3:177,891,705...177,909,743
Ensembl chr 3:177,891,705...177,909,743
JBrowse link
G Sardh sarcosine dehydrogenase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SARDH mRNA CTD PMID:33854195 NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SCNN1A mRNA CTD PMID:33854195 NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405
JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SDR42E1 mRNA CTD PMID:33854195 NCBI chr19:62,624,130...62,636,652
Ensembl chr19:62,624,150...62,636,756
JBrowse link
G Serpina1 serpin family A member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SERPINA1 mRNA CTD PMID:33854195 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255
JBrowse link
G Setd6 SET domain containing 6, protein lysine methyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA CTD PMID:33854195 NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SFRP2 gene CTD PMID:33854195 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SH3BP2 mRNA CTD PMID:33854195 NCBI chr14:80,400,685...80,437,887
Ensembl chr14:80,400,685...80,437,906
JBrowse link
G Sigirr single Ig and TIR domain containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SIGIRR mRNA CTD PMID:33854195 NCBI chr 1:205,625,742...205,637,883
Ensembl chr 1:205,627,708...205,637,802
JBrowse link
G Sik2 salt-inducible kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SIK2 mRNA CTD PMID:33854195 NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:60,121,913...60,221,818
JBrowse link
G Slc12a6 solute carrier family 12, member 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC12A6 mRNA CTD PMID:33854195 NCBI chr 3:119,525,521...119,624,655
Ensembl chr 3:119,526,295...119,624,653
JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC20A1 mRNA CTD PMID:33854195 NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249
JBrowse link
G Slc25a39 solute carrier family 25, member 39 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC25A39 mRNA CTD PMID:33854195 NCBI chr10:87,862,630...87,867,626
Ensembl chr10:87,862,631...87,866,973
JBrowse link
G Slc26a6 solute carrier family 26 member 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC26A6 mRNA CTD PMID:33854195 NCBI chr 8:118,438,110...118,448,271
Ensembl chr 8:118,438,180...118,448,270
JBrowse link
G Slc37a2 solute carrier family 37 member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC37A2 mRNA CTD PMID:33854195 NCBI chr 8:45,134,596...45,160,551
Ensembl chr 8:45,134,596...45,277,989
JBrowse link
G Slk STE20-like kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SLK gene CTD PMID:33854195 NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829
JBrowse link
G Smad7 SMAD family member 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849
JBrowse link
G Smpx small muscle protein, X-linked multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SMPX gene CTD PMID:33854195 NCBI chr  X:41,049,354...41,107,323
Ensembl chr  X:41,049,356...41,107,137
JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SNRNP200 mRNA CTD PMID:33854195 NCBI chr 3:134,882,173...134,911,512
Ensembl chr 3:134,882,173...134,911,500
JBrowse link
G Snx4 sorting nexin 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA CTD PMID:33854195 NCBI chr11:80,965,965...81,023,234
Ensembl chr11:80,965,967...81,028,448
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SOCS3 mRNA CTD PMID:33854195 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SOD3 mRNA CTD PMID:33854195 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
JBrowse link
G Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SOHLH1 gene CTD PMID:33854195 NCBI chr 3:29,061,267...29,065,588
Ensembl chr 3:29,061,267...29,065,588
JBrowse link
G Spag1 sperm associated antigen 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SPAG1 mRNA CTD PMID:33854195 NCBI chr 7:69,246,301...69,306,483
Ensembl chr 7:69,246,582...69,306,482
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SRD5A2 gene CTD PMID:33854195 NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:27,178,079...27,217,588
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRRM2 mRNA CTD PMID:33854195 NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRSF5 mRNA CTD PMID:33854195 NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:106,336,756...106,341,931
JBrowse link
G Stard9 StAR-related lipid transfer domain containing 9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of STARD9 mRNA CTD PMID:33854195 NCBI chr 3:128,034,866...128,150,493
Ensembl chr 3:128,034,908...128,127,402
JBrowse link
G Susd2 sushi domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA CTD PMID:33854195 NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,016,907...13,024,264
JBrowse link
G Sympk symplekin scaffold protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SYMPK mRNA CTD PMID:33854195 NCBI chr 1:87,800,416...87,828,727
Ensembl chr 1:87,799,853...87,828,727
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b affects expression EXP Thiabendazole affects the expression of TAF9B mRNA CTD PMID:18539377 NCBI chr  X:75,354,823...75,366,166
Ensembl chr  X:75,354,825...75,366,414
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TAT mRNA CTD PMID:33854195 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TDP2 mRNA CTD PMID:33854195 NCBI chr17:40,656,969...40,668,362
Ensembl chr17:40,656,971...40,668,288
JBrowse link
G Tead2 TEA domain transcription factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TEAD2 mRNA CTD PMID:33854195 NCBI chr 1:104,838,795...104,855,635
Ensembl chr 1:104,838,623...104,855,630
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TECR mRNA CTD PMID:33854195 NCBI chr19:41,431,422...41,472,880
Ensembl chr19:41,446,071...41,474,432
JBrowse link
G Tgds TDP-glucose 4,6-dehydratase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TGDS mRNA CTD PMID:33854195 NCBI chr15:101,581,765...101,602,779
Ensembl chr15:101,582,227...101,602,718
JBrowse link
G Tgfbi transforming growth factor, beta induced multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TGFBI mRNA CTD PMID:33854195 NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
JBrowse link
G Tjap1 tight junction associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA CTD PMID:33854195 NCBI chr 9:22,198,984...22,223,201
Ensembl chr 9:22,199,676...22,223,201
JBrowse link
G Tkt transketolase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TKT mRNA CTD PMID:33854195 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMBIM6 mRNA CTD PMID:33854195 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
JBrowse link
G Tmem268 transmembrane protein 268 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TMEM268 mRNA CTD PMID:33854195 NCBI chr 5:81,990,314...82,016,970
Ensembl chr 5:81,991,367...82,016,968
JBrowse link
G Tmt1b thiol methyltransferase 1B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMT1B mRNA CTD PMID:33854195 NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TNFAIP2 mRNA CTD PMID:33854195 NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:136,298,082...136,311,106
JBrowse link
G Tor3a torsin family 3, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TOR3A mRNA CTD PMID:33854195 NCBI chr13:71,324,073...71,348,625
Ensembl chr13:71,324,076...71,348,624
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Thiabendazole results in increased expression of TP53 mRNA CTD PMID:18539377 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAF3IP2 mRNA CTD PMID:33854195 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:44,517,242...44,609,618
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA CTD PMID:33854195 NCBI chr12:40,826,251...40,840,169
Ensembl chr12:40,825,851...40,841,320
JBrowse link
G Trim3 tripartite motif-containing 3 increases expression EXP Thiabendazole results in increased expression of TRIM3 mRNA CTD PMID:18539377 NCBI chr 1:169,362,751...169,385,430
Ensembl chr 1:169,356,738...169,385,430
JBrowse link
G Trim34 tripartite motif-containing 34 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRIM34 mRNA CTD PMID:33854195 NCBI chr 1:168,119,043...168,130,544
Ensembl chr 1:168,119,074...168,132,059
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TSC22D3 mRNA CTD PMID:33854195 NCBI chr  X:109,006,410...109,066,389
Ensembl chr  X:109,006,420...109,015,519
JBrowse link
G Uba3 ubiquitin-like modifier activating enzyme 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UBA3 mRNA CTD PMID:33854195 NCBI chr 4:131,346,219...131,367,378
Ensembl chr 4:131,346,224...131,367,277
JBrowse link
G Ubb ubiquitin B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBB mRNA CTD PMID:33854195 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335
JBrowse link
G Ubc ubiquitin C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBC mRNA CTD PMID:33854195 NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275
JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UCKL1 mRNA CTD PMID:33854195 NCBI chr 3:189,052,365...189,064,939
Ensembl chr 3:189,052,365...189,064,967
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP Thiabendazole results in increased expression of UGDH mRNA CTD PMID:18539377 NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Thiabendazole results in increased expression of UGT1A1 mRNA CTD PMID:39207506 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Unc45a unc-45 myosin chaperone A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UNC45A mRNA CTD PMID:33854195 NCBI chr 1:143,691,183...143,705,944
Ensembl chr 1:143,691,186...143,707,312
JBrowse link
G Uox urate oxidase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UOX mRNA CTD PMID:33854195 NCBI chr 2:238,147,130...238,183,320
Ensembl chr 2:238,083,686...238,183,370
JBrowse link
G Usp2 ubiquitin specific peptidase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of USP2 mRNA CTD PMID:33854195 NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:53,308,303...53,336,794
JBrowse link
G Usp40 ubiquitin specific peptidase 40 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA CTD PMID:33854195 NCBI chr 9:96,055,741...96,126,766
Ensembl chr 9:96,055,741...96,126,721
JBrowse link
G Utrn utrophin increases expression ISO Thiabendazole results in increased expression of UTRN mRNA CTD PMID:22028826 NCBI chr 1:8,541,061...9,044,487
Ensembl chr 1:8,542,798...9,044,487
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of VEGFA mRNA CTD PMID:33854195 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Vnn3 vanin 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VNN3 mRNA CTD PMID:33854195 NCBI chr 1:23,390,596...23,402,858
Ensembl chr 1:23,390,596...23,402,858
JBrowse link
G Vtn vitronectin multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VTN mRNA CTD PMID:33854195 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860
JBrowse link
G Wdr11 WD repeat domain 11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of WDR11 gene CTD PMID:33854195 NCBI chr 1:193,595,606...193,641,149
Ensembl chr 1:193,595,535...193,641,142
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of WEE1 mRNA CTD PMID:33854195 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449
JBrowse link
G Wfdc9 WAP four-disulfide core domain 9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of WFDC9 gene CTD PMID:33854195 NCBI chr 3:173,799,888...173,808,383
Ensembl chr 3:173,799,888...173,803,066
JBrowse link
G Yod1 YOD1 deubiquitinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of YOD1 gene CTD PMID:33854195 NCBI chr13:44,727,319...44,733,933 JBrowse link
G Zfc3h1 zinc finger, C3H1-type containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFC3H1 mRNA CTD PMID:33854195 NCBI chr 7:52,894,417...52,950,755
Ensembl chr 7:52,894,172...52,950,758
JBrowse link
G Zfp280d zinc finger protein 280D multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP280D mRNA CTD PMID:33854195 NCBI chr 8:81,872,108...81,961,194
Ensembl chr 8:81,873,335...81,961,201
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP36L2 mRNA CTD PMID:33854195 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653
JBrowse link
G Zfp422 zinc finger protein 422 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP422 mRNA CTD PMID:33854195 NCBI chr 4:151,558,254...151,565,730
Ensembl chr 4:151,556,738...151,566,152
JBrowse link
G Zfp455 zinc finger protein 455 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP455 mRNA CTD PMID:33854195 NCBI chr 2:86,326,568...86,445,514
Ensembl chr 2:86,426,916...86,441,874
JBrowse link
G Zfp598 zinc finger protein 598 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP598 mRNA CTD PMID:33854195 NCBI chr10:14,198,763...14,210,773
Ensembl chr10:14,185,611...14,210,772
JBrowse link
G Zmym3 zinc finger MYM-type containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM3 mRNA CTD PMID:33854195 NCBI chr  X:70,568,573...70,584,221
Ensembl chr  X:70,568,573...70,584,768
JBrowse link
G Zmym6 zinc finger MYM-type containing 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM6 mRNA CTD PMID:33854195 NCBI chr 5:144,680,819...144,728,805
Ensembl chr 5:144,681,197...144,728,803
JBrowse link
G Zranb2 zinc finger RANBP2-type containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZRANB2 mRNA CTD PMID:33854195 NCBI chr 2:249,232,010...249,245,786
Ensembl chr 2:249,232,010...249,245,780
JBrowse link
veliparib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport ISO ABCB1 protein results in increased transport of veliparib CTD PMID:21436403 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO veliparib promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]; veliparib promotes the reaction [Nitroprusside results in increased phosphorylation of AKT1 protein] CTD PMID:30296409 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases activity
ISO veliparib results in increased phosphorylation of and results in increased activity of ATM protein
veliparib results in increased activity of ATM protein
CTD PMID:21917757 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO BAK1 protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] CTD PMID:18376143 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO BAX protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] CTD PMID:18376143 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO BCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] CTD PMID:18376143 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Brca1 BRCA1, DNA repair associated affects response to substance
decreases response to substance
ISO BRCA1 affects the susceptibility to veliparib
BRCA1 protein results in decreased susceptibility to veliparib
CTD PMID:21633166 PMID:21707865 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
JBrowse link
G Brca2 BRCA2, DNA repair associated affects response to substance ISO BRCA2 affects the susceptibility to veliparib CTD PMID:21633166 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
JBrowse link
G Cdk12 cyclin-dependent kinase 12 affects response to substance ISO CDK12 protein affects the susceptibility to veliparib CTD PMID:27880910 NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO CYP1A2 protein results in increased metabolism of veliparib CTD PMID:21436403 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases metabolic processing ISO CYP2C19 protein results in increased metabolism of veliparib CTD PMID:21436403 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of veliparib CTD PMID:21436403 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of veliparib CTD PMID:21436403 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Egfr epidermal growth factor receptor decreases response to substance
affects localization
ISO EGFR protein results in decreased susceptibility to veliparib
veliparib affects the localization of EGFR protein
CTD PMID:21719137 PMID:21912620 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions ISO ERCC1 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]] CTD PMID:21227924 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions ISO ERCC4 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]] CTD PMID:21227924 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions ISO veliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate] CTD PMID:25136123 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
ISO [veliparib co-treated with Topotecan] results in increased expression of H2AX protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]; ERCC1 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]; ERCC4 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]; TDP1 protein inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]; veliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of H2AX protein modified form]; veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]
[veliparib results in increased expression of PARP1 protein] which results in increased expression of H2AX protein; veliparib results in increased expression of H2AX protein; veliparib results in increased expression of H2AX protein modified form
CTD PMID:17505006 PMID:21227924 PMID:21795476 PMID:21917757 PMID:27694308 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO veliparib inhibits the reaction [S100B protein results in increased expression of IL1B mRNA] CTD PMID:27444121 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Mpg N-methylpurine-DNA glycosylase multiple interactions ISO MPG protein promotes the reaction [veliparib results in increased susceptibility to temozolomide] CTD PMID:21377995 NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease decreases response to substance ISO MRE11 protein results in decreased susceptibility to veliparib CTD PMID:21300766 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO veliparib inhibits the reaction [S100B protein results in increased expression of NOS2 mRNA] CTD PMID:27444121 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases activity
increases expression
ISO PARP1 protein affects the susceptibility to [Temozolomide co-treated with veliparib]; veliparib binds to and results in decreased activity of PARP1 protein; veliparib inhibits the reaction [Hydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]]; veliparib inhibits the reaction [PARP1 protein mutant form affects the abundance of NAD]; veliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of H2AX protein modified form]; veliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of RPA2 protein modified form]
veliparib results in decreased activity of PARP1 protein
[veliparib results in increased expression of PARP1 protein] which results in increased expression of H2AX protein; veliparib results in increased expression of PARP1 protein; veliparib results in increased expression of PARP1 protein mutant form
[veliparib results in decreased activity of PARP1 protein] which results in increased susceptibility to Camptothecin
CTD PMID:17505006 PMID:19143569 PMID:19823047 PMID:19825992 PMID:21300766 More... NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Parp10 poly (ADP-ribose) polymerase family, member 10 affects binding ISO veliparib binds to PARP10 protein CTD PMID:28001384 NCBI chr 7:109,829,721...109,839,054
Ensembl chr 7:109,829,722...109,843,566
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 affects binding
multiple interactions
decreases activity
ISO PARP2 protein binds to veliparib
veliparib binds to and results in decreased activity of PARP2 protein
veliparib results in decreased activity of PARP2 protein
CTD PMID:19143569 PMID:20092359 PMID:21917757 PMID:28001384 NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891
JBrowse link
G Pten phosphatase and tensin homolog decreases response to substance ISO PTEN protein results in decreased susceptibility to veliparib CTD PMID:20530668 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
JBrowse link
G Rpa2 replication protein A2 multiple interactions ISO veliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of RPA2 protein modified form] CTD PMID:27694308 NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546
JBrowse link
G S100b S100 calcium binding protein B multiple interactions ISO veliparib inhibits the reaction [S100B protein results in increased expression of IL1B mRNA]; veliparib inhibits the reaction [S100B protein results in increased expression of NOS2 mRNA] CTD PMID:27444121 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 multiple interactions ISO TDP1 protein inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]] CTD PMID:21227924 NCBI chr 6:124,892,821...124,960,646
Ensembl chr 6:124,881,574...124,960,642
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions ISO veliparib affects the reaction [[XRCC1 protein affects the susceptibility to Camptothecin] which affects the abundance of NAD] CTD PMID:35778544 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 20841
    chemical entity 20839
      atom 20839
        nonmetal atom 20747
          nitrogen atom 19577
            nitrogen molecular entity 19577
              organonitrogen compound 19407
                organonitrogen heterocyclic compound 18549
                  benzimidazoles 1217
                    (2R,4S)-N-\{(1R,2R)-4-[(1H-benzimidazol-2-ylmethyl)amino]-1-benzyl-2-hydroxy-4-oxobutyl\}-2-\{(1R)-2-(benzylamino)-2-oxo-1-[(phenylacetyl)amino]ethyl\}-5,5-dimethyl-1,3-thiazolidine-4-carboxamide 0
                    (2S,4R)-N-(1H-benzimidazol-2-ylmethyl)-4-cyclohexyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-carboxamide 0
                    (5S)-5-\{4-[(2S)-2-(1H-benzimidazol-2-yl)-2-(1,3-benzothiazol-2-ylamino)ethyl]phenyl\}isothiazolidin-3-one 1,1-dioxide 0
                    (6-chloro-1H-benzimidazol-2-yl)-(4-methyl-1-piperazinyl)methanone 0
                    1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol 0
                    1-(1H-benzimidazol-2-yl)-3-cyclohexylurea 0
                    1-(2,4-dichlorobenzoyl)-1H-benzimidazole 0
                    1-(2,4-difluorophenyl)-2-methyl-N-[2-(4-morpholinyl)ethyl]-5-benzimidazolecarboxamide 0
                    1-(2-chlorophenoxy)-3-(2-methyl-1-benzimidazolyl)-2-propanol 0
                    1-(2-chlorophenyl)-3-[[(1-ethyl-2-methyl-5-benzimidazolyl)-oxomethyl]amino]thiourea 0
                    1-(2-deoxyribosyl)benzimidazole + 0
                    1-(2-furanyl)-2-(3-heptyl-2-imino-1-benzimidazolyl)ethanol 0
                    1-(2-methoxyethyl)-2-[(4-methoxyphenoxy)methyl]benzimidazole 0
                    1-(2-methoxyethyl)-2-[(4-methylphenoxy)methyl]benzimidazole 0
                    1-(2-methylpropyl)-2-thiophen-2-ylbenzimidazole 0
                    1-(4-ethylphenyl)-2-methyl-N-(3-pyridinylmethyl)-5-benzimidazolecarboxamide 0
                    1-(4-morpholinyl)-2-[2-(phenylmethylthio)-1-benzimidazolyl]ethanone 0
                    1-(5-\{[3-(1H-benzimidazol-2-yl)propanoyl]amino\}-5-deoxy-alpha-L-lyxofuranosyl)cytosine 0
                    1-(5-bromo-2-thiophenyl)-2-[(5-ethoxy-1-methyl-2-benzimidazolyl)thio]ethanone 0
                    1-(5-bromo-2-thiophenyl)-2-[(5-methoxy-1-methyl-2-benzimidazolyl)thio]ethanone 0
                    1-(Piperidinomethyl)-1H-benzo[d]imidazole 0
                    1-(phenylmethyl)benzimidazole 0
                    1-[(3,4-difluorophenyl)methyl]-2-oxo-N-[(1R)-2-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)oxy]-1-phenylethyl]-3-pyridinecarboxamide 0
                    1-[(3-methylphenyl)methyl]benzimidazole 0
                    1-[1-(cyclooctylmethyl)-5-(hydroxymethyl)-3,6-dihydro-2H-pyridin-4-yl]-3-ethyl-2-benzimidazolone 0
                    1-[2-(2-chlorophenoxy)ethyl]benzimidazole 0
                    1-[2-imino-3-[2-(1-piperidinyl)ethyl]-1-benzimidazolyl]-3-(3-methylphenoxy)-2-propanol 0
                    1-[3-[2-(diethylamino)ethyl]-2-imino-1-benzimidazolyl]-3-(3-methylphenoxy)-2-propanol 0
                    1-[4-(1H-benzimidazol-2-yl)phenyl]-3-[3-(4-morpholinyl)propyl]thiourea 0
                    1-[[2-(1H-benzimidazol-2-ylthio)-1-oxoethyl]amino]-3-ethylthiourea 0
                    1-azepanyl-[2-(phenylmethyl)-1-benzimidazolyl]methanone 0
                    1-butyl-2-(2-methylphenyl)-7-propan-2-yl-5H-imidazo[4,5-g]quinoxalin-6-one 0
                    1-cyclohexyl-N-(3-methylbutyl)-5-benzimidazolecarboxamide 0
                    1-cyclopentyl-1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2-oxolanylmethyl)thiourea 0
                    1-cyclopropyl-3-[3-[5-(4-morpholinylmethyl)-2-benzimidazolylidene]-1,2-dihydropyrazol-4-yl]urea 0
                    1-erythrosylbenzimidazole + 0
                    1-ethyl-2-[(4-methylphenoxy)methyl]benzimidazole 0
                    1-ethyl-2-[[(1-methyl-2-benzimidazolyl)thio]methyl]benzimidazole 0
                    1-ethyl-2-methyl-N-[(phenylmethylene)amino]-5-benzimidazolecarboxamide 0
                    1-ethyl-3-[[2-[(1-methyl-2-benzimidazolyl)thio]-1-oxoethyl]amino]thiourea 0
                    1-ethyl-N-[(4-methoxyphenyl)methyl]-5-benzimidazolamine 0
                    1-ethyl-N-[[1-(phenylmethyl)-2-benzimidazolyl]methyl]-5-benzimidazolamine 0
                    1-methyl-3-phenylpyrazino[1,2-a]benzimidazole 0
                    1-ribosylbenzimidazole + 36
                    11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrile 0
                    11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrile 0
                    1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]- 0
                    1H-benzimidazol-5-ylmethanol 0
                    1H-benzimidazole-5,6-diamine 0
                    1H-benzo[d]imidazole-2-thiol 1
                    2''-(4-methoxyphenyl)-5-(3-aminopyrrolidin-1-yl)-2,5',2',5''-ter(benzimidazole) 0
                    2,2'-[3-(2-methoxyphenyl)-1,2-propanediyl]bis(1H-benzimidazole) 0
                    2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazole 0
                    2-(1H-Benzimidazol-2-yl)-N-(4-phenylmethoxyphenyl)benzamide 0
                    2-(1H-benzimidazol-2-yl)-1-(4-chlorophenyl)ethanamine 0
                    2-(1H-benzimidazol-2-yl)-3-(2-furanyl)-2-propenenitrile 0
                    2-(1H-benzimidazol-2-yl)-3-(3-nitrophenyl)-2-propenenitrile 0
                    2-(1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                    2-(1H-benzimidazol-2-yl)-3-oxo-4-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)thio]butanenitrile 0
                    2-(1H-benzimidazol-2-yl)-5-methyl-4-(phenylmethyl)-4H-pyrazol-3-one 0
                    2-(1H-benzimidazol-2-yl)aniline 0
                    2-(1H-benzimidazol-2-ylmethoxymethyl)-1H-benzimidazole 0
                    2-(1H-benzimidazol-2-ylmethoxymethyl)-6-nitro-1H-benzimidazole 0
                    2-(1H-benzimidazol-2-ylmethyl)benzene-1,4-diol 0
                    2-(1H-benzimidazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanone 0
                    2-(1H-benzimidazol-2-ylthio)-1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]ethanone 0
                    2-(1H-benzimidazol-2-ylthio)-1-thiophen-2-ylethanone 0
                    2-(1H-benzimidazol-2-ylthio)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide 0
                    2-(1H-benzimidazol-2-ylthio)acetic acid methyl ester 0
                    2-(2,3,3-trichloro-1-nitroprop-2-enylidene)-1,3-dihydrobenzimidazole 0
                    2-(2,5-dimethylphenyl)-3H-benzimidazol-5-amine 0
                    2-(2-chloro-3-pyridinyl)-1-prop-2-enylbenzimidazole 0
                    2-(2-methyl-2-pyrrolidinyl)-1H-benzimidazole-4-carboxamide 0
                    2-(2-phenoxyethylsulfonyl)-1H-benzimidazole 0
                    2-(3-methyl-2-oxo-1-benzimidazolyl)acetonitrile 0
                    2-(4-\{5-[(1H-benzimidazol-2-ylamino)methyl]thiophen-2-yl\}-1,3-thiazol-2-yl)guanidine 0
                    2-(4-cyanophenoxy)-N-(2-methyl-1-phenyl-5-benzimidazolyl)acetamide 0
                    2-(4-methoxyphenyl)-1-(2-methylprop-2-enyl)benzimidazole 0
                    2-(4-methyl-1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                    2-(5-methyl-1,3-dihydrobenzimidazol-2-ylidene)-2-nitrosoacetonitrile 0
                    2-(6-chloro-3-pyridinyl)-1H-benzimidazole 0
                    2-(6-methyl-1H-benzimidazol-2-yl)-3-(5-methyl-2-furanyl)-2-propenenitrile 0
                    2-(6-methyl-1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                    2-(Methoxymethyl)-1-methyl-1H-benzimidazole 0
                    2-(beta-D-glucosyl)benzimidazole 0
                    2-(trifluoromethyl)-1H-benzo[d]imidazole 0
                    2-Amino-1-methylbenzimidazole 0
                    2-Butyl-1H-benzimidazole 0
                    2-Isopropyl-1H-benzo[d]imidazole 0
                    2-Methyl-1H-benzo[d]imidazole 0
                    2-[(1,5-dimethyl-2-benzimidazolyl)amino]ethanol 0
                    2-[(1-acetyl-2-benzimidazolyl)thio]-N-(2-methoxyphenyl)acetamide 0
                    2-[(2,2-dichloro-3,3-dimethylcyclopropyl)methylthio]-1H-benzimidazole 0
                    2-[(2,5-dimethylphenyl)thio]acetic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester 0
                    2-[(2-ethoxy-2-oxoethyl)thio]-1-benzimidazolecarboxylic acid ethyl ester 0
                    2-[(2-methoxyphenoxy)methyl]-1H-benzimidazole 0
                    2-[(3S)-1-(1-Methyl-4-piperidinyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                    2-[(3S)-1-(3,4-Difluorobenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                    2-[(3S)-1-(4-Chlorobenzyl)-3-pyrrolidinyl]-1-methyl-1H-benzimidazole 0
                    2-[(3S)-1-(Cyclohexylmethyl)-3-pyrrolidinyl]-5-methyl-1H-benzimidazole 0
                    2-[(3s)-1-(cyclohexylmethyl)-3-pyrrolidinyl]-5-fluoro-1h-benzimidazole 0
                    2-[(4-cyano-1-oxo-5H-pyrido[1,2-a]benzimidazol-3-yl)methylthio]propanoic acid 0
                    2-[(6-chloro-1H-benzimidazol-2-yl)thio]-N-(2,3-dihydro-1H-inden-5-yl)acetamide 0
                    2-[(6-chloro-2-phenyl-1-benzimidazolyl)oxy]acetic acid 0
                    2-[(6-methyl-1H-benzimidazol-2-yl)thio]-1-(2-methyl-1H-indol-3-yl)ethanone 0
                    2-[2-(2-chlorophenyl)-1-benzimidazolyl]-N-(2,6-diethylphenyl)acetamide 0
                    2-[2-(2-chlorophenyl)-1-benzimidazolyl]-N-(2-propan-2-ylphenyl)acetamide 0
                    2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine 0
                    2-[2-(ethylthio)-1-benzimidazolyl]-1-(1-piperidinyl)ethanone 0
                    2-[2-[2-[(1,3-dimethyl-2-oxo-5-benzimidazolyl)methylidene]hydrazinyl]-4-oxo-5-thiazolyl]acetic acid 0
                    2-[5-(4-carbamimidoylphenyl)furan-2-yl]-1H-benzimidazole-5-carboximidamide 0
                    2-[5-[(5,7-dimethyl-1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid 0
                    2-[5-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-furanyl]benzoic acid 0
                    2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amine 0
                    2-[[(1-butyl-2-benzimidazolyl)amino]methyl]phenol 0
                    2-[[(1-propan-2-yl-2-benzimidazolyl)amino]methyl]-6-prop-2-enylphenol 0
                    2-[[(6-bromo-1H-benzimidazol-2-yl)thio]methyl]-1-methylbenzimidazole 0
                    2-[[2-(2-methylphenoxy)ethylthio]methyl]-1H-benzimidazole 0
                    2-[[3-(1H-benzimidazol-2-yl)-2-pyridinyl]thio]acetic acid methyl ester 0
                    2-[[5-(1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide 0
                    2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(4-methyl-2-thiazolyl)acetamide 0
                    2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamide 0
                    2-[[5-[2-(1H-benzimidazol-2-yl)ethyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide 0
                    2-[[5-[2-(1H-benzimidazol-2-yl)ethyl]-4-methyl-1,2,4-triazol-3-yl]thio]acetonitrile 0
                    2-[[6-(butylsulfamoyl)-1H-benzimidazol-2-yl]thio]-N-(2-chlorophenyl)acetamide 0
                    2-[[6-(dimethylsulfamoyl)-1H-benzimidazol-2-yl]methoxymethyl]-N,N-dimethyl-3H-benzimidazole-5-sulfonamide 0
                    2-[[[2-methyl-1-(phenylmethyl)-5-benzimidazolyl]amino]methyl]phenol 0
                    2-[[[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]methyl]benzonitrile 0
                    2-[fluoro(trifluoromethoxy)methyl]-6-methyl-1H-benzimidazole 0
                    2-aminobenzimidazole + 86
                    2-benzamido-1-(3-phenylpropyl)-5-benzimidazolecarboxylic acid methyl ester 0
                    2-ethyl-1-[(2-methoxyphenyl)methyl]benzimidazole 0
                    2-ethyl-N-[1-[2-(1-piperidinyl)ethyl]-2-benzimidazolyl]-3-pyrazolecarboxamide 0
                    2-methoxy-1-(1-methyl-2-benzimidazolyl)-1-phenylethanamine 0
                    2-methoxy-N-[(1-methyl-2-benzimidazolyl)methyl]aniline 0
                    2-methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(2-methoxyanilino)-2-oxoethyl] ester 0
                    2-methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(3-methylbutan-2-ylamino)-2-oxoethyl] ester 0
                    2-methyl-1H-benzimidazole-5-carboxylic acid 0
                    2-methyl-1H-pyrimido[1,2-a]benzimidazol-4-one 0
                    2-methyl-N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]propanamide 0
                    2-methylpropanoic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester 0
                    2-phenyl-2,3-dihydro-[1,3]thiazino[3,2-a]benzimidazol-4-one 0
                    3,4,5-trimethoxy-N-[2-(1-methyl-2-benzimidazolyl)ethyl]benzamide 0
                    3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol 0
                    3,4-dimethyl-N-[[(2-oxo-1,3-dihydrobenzimidazol-5-yl)amino]-sulfanylidenemethyl]benzamide 0
                    3-(1-benzimidazolylmethyl)-6-[(4-methoxyphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                    3-(1H-benzimidazol-2-yl)-N-(3-pyridinylmethyl)aniline 0
                    3-(1H-benzimidazol-2-ylthio)-5,5-dimethyl-3-(1-oxopropyl)-2-oxolanone 0
                    3-(2-phenoxyethyl)-1H-benzimidazole-2-thione 0
                    3-(6-amino-1H-benzimidazol-2-yl)-1-propanol 0
                    3-(6-amino-1H-benzimidazol-2-yl)propanoic acid 0
                    3-Hydroxyomeprazole 0
                    3-[(7-carbamimidoylnaphthalen-2-yl)methyl]-5-(\{1-[(1Z)-ethanimidoyl]piperidin-4-yl\}oxy)-2-methyl-1H-3,1-benzimidazol-3-ium 0
                    3-[1-(2-carboxyethyl)-1H-benzo[d]imidazol-2-yl]propanoic acid 0
                    3-[1-[(4-methyl-6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-1H-benzimidazol-2-one 0
                    3-[1-butyl-5-(diethylsulfamoyl)-2-benzimidazolyl]propanoic acid 0
                    3-[2-(4-methyl-2-propan-2-ylphenoxy)ethyl]-1H-benzimidazole-2-thione 0
                    3-[3-[[2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl]thio]propyl]-1H-benzimidazol-2-one 0
                    3-[5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl]propan-1-ol 0
                    3-[5-(diethylsulfamoyl)-1-methyl-2-benzimidazolyl]propanoic acid [2-(3,5-dichloroanilino)-2-oxoethyl] ester 0
                    3-[5-(dimethylsulfamoyl)-1-ethyl-2-benzimidazolyl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)propanamide 0
                    3-[5-(dimethylsulfamoyl)-1-ethyl-2-benzimidazolyl]propanoic acid 0
                    3-\{[2-(1H-benzimidazol-1-yl)-6-\{[2-(diethylamino)ethyl]amino\}pyrimidin-4-yl]amino\}-4-methylphenol 0
                    4,5,6,7-tetrabromobenzimidazole 0
                    4-(1-ethyl-2-benzimidazolyl)aniline 0
                    4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine 0
                    4-(4-chloro-3-nitrophenyl)-N-[2-(5,6-dichloro-1-propyl-2-benzimidazolyl)ethyl]-2-thiazolamine 0
                    4-(5,6-Dichloro-1H-benzimidazol-1-yl)butan-1-ol 0
                    4-[(1H-benzimidazol-2-ylhydrazinylidene)methyl]benzoic acid 0
                    4-[(1H-benzimidazol-2-ylthio)methyl]-2-thiazolamine 0
                    4-[(6-chloro-1H-benzimidazol-2-yl)amino]benzoic acid 0
                    4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine 0
                    4-[1-[(3-methoxyphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine 0
                    4-[2-(1-methyl-2-benzimidazolyl)ethyl]aniline 0
                    4-[2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]-1-oxoethyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester 0
                    4-[2-[[1-(phenylmethyl)-2-benzimidazolyl]thio]ethyl]morpholine 0
                    4-[5-[(1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid 0
                    4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-pyridinone 0
                    4-[[2-(phenylmethyl)-1-benzimidazolyl]sulfonyl]morpholine 0
                    4-ethyl-3-hydroxy-6-[5-methyl-4-(1-methyl-2-benzimidazolyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone 0
                    4-methyl-N-[1-[2-(1-pyrrolidinyl)ethyl]-2-benzimidazolyl]benzamide 0
                    4-oxo-10H-pyrimido[1,2-a]benzimidazole-3-carboxylic acid ethyl ester 0
                    4H-[1,3]thiazino[3,2-a]benzimidazol-4-ol 0
                    5'-O-Desmethyl omeprazole 0
                    5'-hydroxyomeprazole 1
                    5,6-dimethyl-1-octyl-4-benzimidazolamine 0
                    5,6-dimethyl-2-[1-[[1-(phenylmethyl)-5-tetrazolyl]methyl]-4-piperidinyl]-1H-benzimidazole 0
                    5,6-dimethyl-2-[2-(1-pyrrolidinyl)ethylthio]-1H-benzimidazole 0
                    5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde 0
                    5-(1H-benzimidazol-2-ylmethylidene)-3-(4-fluorophenyl)-2-sulfanylidene-4-thiazolidinone 0
                    5-(2,3-dihydroindol-1-ylsulfonyl)-1,3-diethyl-2-benzimidazolone 0
                    5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile 0
                    5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(4-methylsulfonylphenyl)methoxy]-2-thiophenecarboxamide 0
                    5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one 0
                    5-Fluoro-2-[(3S)-1-(2-fluorobenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                    5-Fluoro-2-[(3S)-1-(2-methylbenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                    5-Hydroxyemedastine 0
                    5-Hydroxymebendazole 0
                    5-Hydroxythiabendazole 0
                    5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid 0
                    5-[[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4-pyrazolylidene]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                    5-[[3-bromo-4-[(2-fluorophenyl)methoxy]-5-methoxyphenyl]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                    5-[[3-methyl-1-(4-methylphenyl)-5-oxo-4-pyrazolylidene]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                    5-[[4-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-ethoxyphenoxy]methyl]-2-furancarboxylic acid 0
                    5-[[4-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-methoxyphenoxy]methyl]-2-furancarboxylic acid 0
                    5-amino-4-(1H-benzimidazol-2-yl)-1-pentyl-2H-pyrrol-3-one 0
                    5-amino-4-(1H-benzimidazol-2-yl)-1-propan-2-yl-2H-pyrrol-3-one 0
                    5-chloro-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazole-2-thione 0
                    5-ethoxy-2-[(2,3,4,5,6-pentafluorobenzyl)thio]-1H-benzo[d]imidazole 0
                    5-hydroxybenzimidazole 0
                    5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole + 411
                    6-(1H-benzimidazol-2-yl)-2-methyl-1H-benzimidazole 0
                    6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazole 0
                    6-Hydroxyemedastine 0
                    6-[3-[(2-hydroxyphenyl)methyl]-1H-benzimidazol-2-ylidene]-1-cyclohexa-2,4-dienone 0
                    6-fluoro-2-[(6-fluoro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole 0
                    6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole 0
                    6-methyl-2-(trifluoromethyl)-3,5-dihydroimidazo[4,5-f]benzimidazole 0
                    6-methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazole 0
                    6-nitro-3-phenyl-1H-benzimidazole-2-thione 0
                    6-nitro-8-(trifluoromethyl)benzo[4,5]imidazo[1,2-a]pyridine 0
                    7-[[[1-(3-methylphenyl)-2-benzimidazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinone 0
                    7-amino-N-cyclohexyl-1-methyl-2-thiazolo[3,2-a]benzimidazolecarboxamide 0
                    7-amino-N-cyclohexyl-N,1-dimethyl-2-thiazolo[3,2-a]benzimidazolecarboxamide 0
                    AZ3451 0
                    Allyl 2-(1H-benzimidazoL-2-yl)-2-cyano-n-phenylethanimidothioate 0
                    CGP 12177 10
                    CHIR-265 0
                    CHZ868 0
                    Clemizole hydrochloride 0
                    FIPI 0
                    GSK461364 0
                    GW843682X 0
                    L-779976 0
                    LSM-19079 0
                    LSM-1988 0
                    LSM-23645 0
                    LSM-25679 0
                    LSM-28507 0
                    LSM-33057 0
                    ML240 0
                    Mizolastine 2
                    N,N,1-triethyl-2-sulfanylidene-3H-benzimidazole-5-sulfonamide 0
                    N,N,2-trimethyl-1-phenyl-5-benzimidazolesulfonamide 0
                    N-(1,1-dioxo-3-thiolanyl)-N-methyl-2-[[1-(2-phenylethyl)-2-benzimidazolyl]thio]acetamide 0
                    N-(1,3-dimethyl-2-oxo-5-benzimidazolyl)-2-benzofurancarboxamide 0
                    N-(1-benzimidazolyl)-1-(6-chloro-5-imidazo[2,1-b]thiazolyl)methanimine 0
                    N-(1-butyl-2-benzimidazolyl)cyclohexanecarboxamide 0
                    N-(1-methyl-2-benzimidazolyl)-1-thiophen-2-ylmethanimine 0
                    N-(1-propyl-5-benzimidazolyl)-2-thiophenecarboxamide 0
                    N-(1-tert-butyl-5-benzimidazolyl)-2-thiophenecarboxamide 0
                    N-(1-tert-butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide 0
                    N-(1H-1,3-benzodiazol-2-yl)carbamate 0
                    N-(1H-benzimidazol-2-yl)-2-methylsulfonylbenzamide 0
                    N-(1H-benzimidazol-2-yl)-2-nitrobenzamide 0
                    N-(1H-benzimidazol-2-yl)-3-(1-imidazolyl)propanamide 0
                    N-(1H-benzimidazol-2-yl)-3-[(3-\{3-[(1H-benzimidazol-2-ylamino)carbonyl]benzyl\}-4,7-dibenzyl-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl)methyl]benzamide 0
                    N-(1H-benzimidazol-2-yl)-3-phenylbutanamide 0
                    N-(1H-benzimidazol-2-yl)-4-(3-methylphenoxy)butanamide 0
                    N-(1H-benzimidazol-2-yl)carbamic acid ethyl ester 0
                    N-(2-benzimidazolylidenemethyl)-1,2,4-triazol-4-amine 0
                    N-(2-chlorobenzyl)-1-(2,5-dimethylphenyl)benzimidazole-5-carboxamide 0
                    N-(2-ethoxyphenyl)-1H-benzimidazol-2-amine 0
                    N-(2-fluorophenyl)-2-[2-(4-thiazolyl)-1-benzimidazolyl]acetamide 0
                    N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolamine 0
                    N-(2-methyl-1-benzimidazolyl)-1-(5-nitro-2-thiophenyl)methanimine 0
                    N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)butanamide 0
                    N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)pentanamide 0
                    N-(3,5-dichloro-2-pyridinyl)-2-[(1-phenyl-2-benzimidazolyl)thio]acetamide 0
                    N-(3,5-dichloro-2-pyridinyl)-2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]propanamide 0
                    N-(3H-benzimidazol-5-yl)-2-furancarboxamide 0
                    N-(4-methylphenyl)-5-nitro-4-spiro[benzimidazole-2,1'-cyclohexane]amine 0
                    N-(5,6-dimethyl-1-benzimidazolyl)-1-(5-nitro-2-furanyl)methanimine 0
                    N-(5-chloro-2-pyridinyl)-2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]acetamide 0
                    N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester 0
                    N-(cyclohexylmethylideneamino)-1H-benzimidazol-2-amine 0
                    N-[(1S)-1-(1H-benzimidazol-2-yl)-2-\{4-[(5S)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide 0
                    N-[(1S)-1-(1H-benzimidazol-2-yl)-3-(methylthio)propyl]-2-(4-chlorophenoxy)-2-methylpropanamide 0
                    N-[(3-methoxyphenyl)methyl]-1-propyl-5-benzimidazolamine 0
                    N-[1-(1-hexyl-2-benzimidazolyl)ethyl]-2-furancarboxamide 0
                    N-[1-(1H-benzimidazol-2-yl)-3-(methylthio)propyl]-3,5-dinitrobenzamide 0
                    N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamide 0
                    N-[1-(4-methylphenyl)-5-benzimidazolyl]acetamide 0
                    N-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]-2-furancarboxamide 0
                    N-[1-[1-[(3-chlorophenyl)methyl]-2-benzimidazolyl]ethyl]-3-(2-furanyl)-2-propenamide 0
                    N-[1-[1-[2-[4-(diethylamino)anilino]-2-oxoethyl]-2-benzimidazolyl]ethyl]-4-methylbenzamide 0
                    N-[1-[2-(1-piperidinyl)ethyl]-2-benzimidazolyl]-1-thiophen-2-ylmethanimine 0
                    N-[1-[2-(2-chlorophenoxy)ethyl]-2-benzimidazolyl]acetamide 0
                    N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide 0
                    N-[2-(1H-benzimidazol-2-yl)ethyl]-3,5-dinitrobenzamide 0
                    N-[2-(1H-benzimidazol-2-yl)phenyl]-2-thiophen-2-ylacetamide 0
                    N-[2-(2-benzamidoethyl)-1-methyl-5-benzimidazolyl]-2-furancarboxamide 0
                    N-[2-(2-benzamidoethyl)-1-methyl-5-benzimidazolyl]-2-methoxybenzamide 0
                    N-[2-(2-pyridinyl)-3H-benzimidazol-5-yl]cyclohexanecarboxamide 0
                    N-[2-(3-acetamidophenyl)-3H-benzimidazol-5-yl]acetamide 0
                    N-[2-(3-pyridinyl)-3H-benzimidazol-5-yl]-2-furancarboxamide 0
                    N-[2-(4-fluorophenyl)ethyl]-2-[2-(2-hydroxyethylamino)-1-benzimidazolyl]acetamide 0
                    N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 0
                    N-[2-[1-(3-phenylprop-2-enyl)-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                    N-[2-[1-[2-(2,5-difluorophenoxy)ethyl]-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                    N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]cycloheptanecarboxamide 0
                    N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                    N-[2-[1-methyl-5-[[(4-methylphenyl)-oxomethyl]amino]-2-benzimidazolyl]ethyl]-2-furancarboxamide 0
                    N-[2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-2-benzimidazol-3-iumyl]ethenyl]-N-methylaniline 0
                    N-[3-(1H-benzimidazol-2-yl)-5-(1-piperazinylmethyl)phenyl]-2-quinoxalinecarboxamide 0
                    N-[4-(1H-benzimidazol-2-yl)phenyl]-1-[(5-methyl-1H-pyrazol-3-yl)methyl]-3-piperidinecarboxamide 0
                    N-[4-(1H-benzimidazol-2-yl)phenyl]-2,3,4,5,6-pentafluorobenzamide 0
                    N-[4-(1H-benzimidazol-2-yl)phenyl]-2-methyl-4-nitro-3-pyrazolecarboxamide 0
                    N-[4-(1H-benzimidazol-2-yl)phenyl]-3-(2,5-dioxo-1-pyrrolidinyl)benzamide 0
                    N-[4-(1H-benzimidazol-2-yl)phenyl]-4-ethoxy-3-nitrobenzamide 0
                    N-[4-(6-chloro-5-nitro-1H-benzimidazol-2-yl)phenyl]acetamide 0
                    N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-2-(2-nitrophenoxy)acetamide 0
                    N-[6-(propan-2-ylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester 0
                    N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-2-[(1-ethyl-2-benzimidazolyl)thio]-N-methylacetamide 0
                    N-[[1-(2-phenoxyethyl)-2-benzimidazolyl]methyl]aniline 0
                    N-[[4-(diethylamino)phenyl]methyl]-1-[2-(1-piperidinyl)ethyl]-2-benzimidazolamine 0
                    N-[[4-(dimethylamino)phenyl]methyl]-1-ethyl-5-benzimidazolamine 0
                    N-[[5-(1H-benzimidazol-2-yl)-2-chloroanilino]-sulfanylidenemethyl]-2,6-dimethoxybenzamide 0
                    N-[[5-(1H-benzimidazol-2-yl)-2-methylanilino]-sulfanylidenemethyl]-5-chloro-2-methoxybenzamide 0
                    N-\{(1S)-2-\{4-[(5R)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]ethyl\}-2,2,2-trifluoroacetamide 0
                    N-\{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl\}methanesulfonamide 0
                    N-butyl-1H-benzimidazol-2-amine 0
                    N-cycloheptyl-2-[(6-nitro-1H-benzimidazol-2-yl)thio]acetamide 0
                    N-methyl-N-[(1-methyl-1H-benzimidazol-2-yl)methyl]amine 0
                    N-phenyl-1-propan-2-yl-2-benzimidazolamine 0
                    N2-(1H-benzimidazol-2-yl)benzene-1,2-diamine 0
                    NNC 55-0396 (free base) + 0
                    NS 1619 4
                    NS-8593 0
                    Omeprazole sodium 0
                    Omeprazole sulfide 3
                    Omeprazole sulfone 0
                    Ro 18-5364 0
                    ZSTK-474 0
                    [1-(3-methylphenyl)-5-benzimidazolyl]-(1-piperidinyl)methanone 0
                    [1-[3-(4-methylphenoxy)propyl]-2-benzimidazolyl]methanol 0
                    [4-(2-benzimidazolylidene)-3-imino-2-phenyl-1H-pyridazin-6-yl]-thiophen-2-ylmethanone 0
                    albendazole + 48
                    astemizole 89
                    azilsartan medoxomil 0
                    bendamustine 0
                    bendazol 0
                    benomyl 59
                    benzimidazole + 397
                    benzimidazole fungicide + 451
                    benzimidazolecarbaldehyde + 0
                    benzimidazolecarboxylic acid + 80
                    benzimidazolequinone + 0
                    benzimidazolylcarbamate fungicide + 167
                    bibenzimidazole + 6
                    bilastine 0
                    binimetinib 1
                    carbendazim 86
                    chlormidazole 6
                    ciclobendazole 1
                    clemizole 15
                    crenolanib 0
                    dabigatran + 28
                    dabigatran etexilate 0
                    desmethylastemizole 2
                    dexlansoprazole 0
                    dexrabeprazole 0
                    dimethylbenzimidazole + 0
                    domperidone + 20
                    droperidol 2
                    emedastine + 1
                    ensulizole 0
                    fabomotizole 0
                    fenbendazole + 60
                    flibanserin 0
                    flubendazole 15
                    fuberidazole 0
                    glasdegib 0
                    hydroxyalbendazole 0
                    hydroxyfenbendazole 0
                    ilaprazole 0
                    lansoprazole 64
                    liarozole 1
                    magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide 0
                    mebendazole 50
                    methyl 4-oxo-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazine-2-carboxylate 0
                    nocodazole 74
                    oxatomide 4
                    oxfendazole 19
                    pantoprazole 32
                    pantoprazole(1-) + 0
                    parbendazole 1
                    pimobendan 8
                    pimozide 6
                    procodazole 0
                    rabeprazole 18
                    selumetinib 29
                    tarocin B 0
                    tcmdc-123507 0
                    telmisartan 122
                    thiabendazole 338
                    veliparib 30
Path 2
Term Annotations click to browse term
  CHEBI ontology 20841
    subatomic particle 20839
      composite particle 20839
        hadron 20839
          baryon 20839
            nucleon 20839
              atomic nucleus 20839
                atom 20839
                  main group element atom 20762
                    p-block element atom 20786
                      p-block molecular entity 20762
                        carbon group molecular entity 20718
                          organic molecular entity 20690
                            organic molecule 20634
                              organic cyclic compound 20385
                                organic heterocyclic compound 19373
                                  organic heteropolycyclic compound 18633
                                    organic heterobicyclic compound 17513
                                      benzimidazoles 1217
                                        (2R,4S)-N-\{(1R,2R)-4-[(1H-benzimidazol-2-ylmethyl)amino]-1-benzyl-2-hydroxy-4-oxobutyl\}-2-\{(1R)-2-(benzylamino)-2-oxo-1-[(phenylacetyl)amino]ethyl\}-5,5-dimethyl-1,3-thiazolidine-4-carboxamide 0
                                        (2S,4R)-N-(1H-benzimidazol-2-ylmethyl)-4-cyclohexyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-carboxamide 0
                                        (5S)-5-\{4-[(2S)-2-(1H-benzimidazol-2-yl)-2-(1,3-benzothiazol-2-ylamino)ethyl]phenyl\}isothiazolidin-3-one 1,1-dioxide 0
                                        (6-chloro-1H-benzimidazol-2-yl)-(4-methyl-1-piperazinyl)methanone 0
                                        1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol 0
                                        1-(1H-benzimidazol-2-yl)-3-cyclohexylurea 0
                                        1-(2,4-dichlorobenzoyl)-1H-benzimidazole 0
                                        1-(2,4-difluorophenyl)-2-methyl-N-[2-(4-morpholinyl)ethyl]-5-benzimidazolecarboxamide 0
                                        1-(2-chlorophenoxy)-3-(2-methyl-1-benzimidazolyl)-2-propanol 0
                                        1-(2-chlorophenyl)-3-[[(1-ethyl-2-methyl-5-benzimidazolyl)-oxomethyl]amino]thiourea 0
                                        1-(2-deoxyribosyl)benzimidazole + 0
                                        1-(2-furanyl)-2-(3-heptyl-2-imino-1-benzimidazolyl)ethanol 0
                                        1-(2-methoxyethyl)-2-[(4-methoxyphenoxy)methyl]benzimidazole 0
                                        1-(2-methoxyethyl)-2-[(4-methylphenoxy)methyl]benzimidazole 0
                                        1-(2-methylpropyl)-2-thiophen-2-ylbenzimidazole 0
                                        1-(4-ethylphenyl)-2-methyl-N-(3-pyridinylmethyl)-5-benzimidazolecarboxamide 0
                                        1-(4-morpholinyl)-2-[2-(phenylmethylthio)-1-benzimidazolyl]ethanone 0
                                        1-(5-\{[3-(1H-benzimidazol-2-yl)propanoyl]amino\}-5-deoxy-alpha-L-lyxofuranosyl)cytosine 0
                                        1-(5-bromo-2-thiophenyl)-2-[(5-ethoxy-1-methyl-2-benzimidazolyl)thio]ethanone 0
                                        1-(5-bromo-2-thiophenyl)-2-[(5-methoxy-1-methyl-2-benzimidazolyl)thio]ethanone 0
                                        1-(Piperidinomethyl)-1H-benzo[d]imidazole 0
                                        1-(phenylmethyl)benzimidazole 0
                                        1-[(3,4-difluorophenyl)methyl]-2-oxo-N-[(1R)-2-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)oxy]-1-phenylethyl]-3-pyridinecarboxamide 0
                                        1-[(3-methylphenyl)methyl]benzimidazole 0
                                        1-[1-(cyclooctylmethyl)-5-(hydroxymethyl)-3,6-dihydro-2H-pyridin-4-yl]-3-ethyl-2-benzimidazolone 0
                                        1-[2-(2-chlorophenoxy)ethyl]benzimidazole 0
                                        1-[2-imino-3-[2-(1-piperidinyl)ethyl]-1-benzimidazolyl]-3-(3-methylphenoxy)-2-propanol 0
                                        1-[3-[2-(diethylamino)ethyl]-2-imino-1-benzimidazolyl]-3-(3-methylphenoxy)-2-propanol 0
                                        1-[4-(1H-benzimidazol-2-yl)phenyl]-3-[3-(4-morpholinyl)propyl]thiourea 0
                                        1-[[2-(1H-benzimidazol-2-ylthio)-1-oxoethyl]amino]-3-ethylthiourea 0
                                        1-azepanyl-[2-(phenylmethyl)-1-benzimidazolyl]methanone 0
                                        1-butyl-2-(2-methylphenyl)-7-propan-2-yl-5H-imidazo[4,5-g]quinoxalin-6-one 0
                                        1-cyclohexyl-N-(3-methylbutyl)-5-benzimidazolecarboxamide 0
                                        1-cyclopentyl-1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2-oxolanylmethyl)thiourea 0
                                        1-cyclopropyl-3-[3-[5-(4-morpholinylmethyl)-2-benzimidazolylidene]-1,2-dihydropyrazol-4-yl]urea 0
                                        1-erythrosylbenzimidazole + 0
                                        1-ethyl-2-[(4-methylphenoxy)methyl]benzimidazole 0
                                        1-ethyl-2-[[(1-methyl-2-benzimidazolyl)thio]methyl]benzimidazole 0
                                        1-ethyl-2-methyl-N-[(phenylmethylene)amino]-5-benzimidazolecarboxamide 0
                                        1-ethyl-3-[[2-[(1-methyl-2-benzimidazolyl)thio]-1-oxoethyl]amino]thiourea 0
                                        1-ethyl-N-[(4-methoxyphenyl)methyl]-5-benzimidazolamine 0
                                        1-ethyl-N-[[1-(phenylmethyl)-2-benzimidazolyl]methyl]-5-benzimidazolamine 0
                                        1-methyl-3-phenylpyrazino[1,2-a]benzimidazole 0
                                        1-ribosylbenzimidazole + 36
                                        11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrile 0
                                        11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrile 0
                                        1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]- 0
                                        1H-benzimidazol-5-ylmethanol 0
                                        1H-benzimidazole-5,6-diamine 0
                                        1H-benzo[d]imidazole-2-thiol 1
                                        2''-(4-methoxyphenyl)-5-(3-aminopyrrolidin-1-yl)-2,5',2',5''-ter(benzimidazole) 0
                                        2,2'-[3-(2-methoxyphenyl)-1,2-propanediyl]bis(1H-benzimidazole) 0
                                        2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazole 0
                                        2-(1H-Benzimidazol-2-yl)-N-(4-phenylmethoxyphenyl)benzamide 0
                                        2-(1H-benzimidazol-2-yl)-1-(4-chlorophenyl)ethanamine 0
                                        2-(1H-benzimidazol-2-yl)-3-(2-furanyl)-2-propenenitrile 0
                                        2-(1H-benzimidazol-2-yl)-3-(3-nitrophenyl)-2-propenenitrile 0
                                        2-(1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                                        2-(1H-benzimidazol-2-yl)-3-oxo-4-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)thio]butanenitrile 0
                                        2-(1H-benzimidazol-2-yl)-5-methyl-4-(phenylmethyl)-4H-pyrazol-3-one 0
                                        2-(1H-benzimidazol-2-yl)aniline 0
                                        2-(1H-benzimidazol-2-ylmethoxymethyl)-1H-benzimidazole 0
                                        2-(1H-benzimidazol-2-ylmethoxymethyl)-6-nitro-1H-benzimidazole 0
                                        2-(1H-benzimidazol-2-ylmethyl)benzene-1,4-diol 0
                                        2-(1H-benzimidazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanone 0
                                        2-(1H-benzimidazol-2-ylthio)-1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]ethanone 0
                                        2-(1H-benzimidazol-2-ylthio)-1-thiophen-2-ylethanone 0
                                        2-(1H-benzimidazol-2-ylthio)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide 0
                                        2-(1H-benzimidazol-2-ylthio)acetic acid methyl ester 0
                                        2-(2,3,3-trichloro-1-nitroprop-2-enylidene)-1,3-dihydrobenzimidazole 0
                                        2-(2,5-dimethylphenyl)-3H-benzimidazol-5-amine 0
                                        2-(2-chloro-3-pyridinyl)-1-prop-2-enylbenzimidazole 0
                                        2-(2-methyl-2-pyrrolidinyl)-1H-benzimidazole-4-carboxamide 0
                                        2-(2-phenoxyethylsulfonyl)-1H-benzimidazole 0
                                        2-(3-methyl-2-oxo-1-benzimidazolyl)acetonitrile 0
                                        2-(4-\{5-[(1H-benzimidazol-2-ylamino)methyl]thiophen-2-yl\}-1,3-thiazol-2-yl)guanidine 0
                                        2-(4-cyanophenoxy)-N-(2-methyl-1-phenyl-5-benzimidazolyl)acetamide 0
                                        2-(4-methoxyphenyl)-1-(2-methylprop-2-enyl)benzimidazole 0
                                        2-(4-methyl-1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                                        2-(5-methyl-1,3-dihydrobenzimidazol-2-ylidene)-2-nitrosoacetonitrile 0
                                        2-(6-chloro-3-pyridinyl)-1H-benzimidazole 0
                                        2-(6-methyl-1H-benzimidazol-2-yl)-3-(5-methyl-2-furanyl)-2-propenenitrile 0
                                        2-(6-methyl-1H-benzimidazol-2-yl)-3-(5-nitro-2-furanyl)-2-propenenitrile 0
                                        2-(Methoxymethyl)-1-methyl-1H-benzimidazole 0
                                        2-(beta-D-glucosyl)benzimidazole 0
                                        2-(trifluoromethyl)-1H-benzo[d]imidazole 0
                                        2-Amino-1-methylbenzimidazole 0
                                        2-Butyl-1H-benzimidazole 0
                                        2-Isopropyl-1H-benzo[d]imidazole 0
                                        2-Methyl-1H-benzo[d]imidazole 0
                                        2-[(1,5-dimethyl-2-benzimidazolyl)amino]ethanol 0
                                        2-[(1-acetyl-2-benzimidazolyl)thio]-N-(2-methoxyphenyl)acetamide 0
                                        2-[(2,2-dichloro-3,3-dimethylcyclopropyl)methylthio]-1H-benzimidazole 0
                                        2-[(2,5-dimethylphenyl)thio]acetic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester 0
                                        2-[(2-ethoxy-2-oxoethyl)thio]-1-benzimidazolecarboxylic acid ethyl ester 0
                                        2-[(2-methoxyphenoxy)methyl]-1H-benzimidazole 0
                                        2-[(3S)-1-(1-Methyl-4-piperidinyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                                        2-[(3S)-1-(3,4-Difluorobenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                                        2-[(3S)-1-(4-Chlorobenzyl)-3-pyrrolidinyl]-1-methyl-1H-benzimidazole 0
                                        2-[(3S)-1-(Cyclohexylmethyl)-3-pyrrolidinyl]-5-methyl-1H-benzimidazole 0
                                        2-[(3s)-1-(cyclohexylmethyl)-3-pyrrolidinyl]-5-fluoro-1h-benzimidazole 0
                                        2-[(4-cyano-1-oxo-5H-pyrido[1,2-a]benzimidazol-3-yl)methylthio]propanoic acid 0
                                        2-[(6-chloro-1H-benzimidazol-2-yl)thio]-N-(2,3-dihydro-1H-inden-5-yl)acetamide 0
                                        2-[(6-chloro-2-phenyl-1-benzimidazolyl)oxy]acetic acid 0
                                        2-[(6-methyl-1H-benzimidazol-2-yl)thio]-1-(2-methyl-1H-indol-3-yl)ethanone 0
                                        2-[2-(2-chlorophenyl)-1-benzimidazolyl]-N-(2,6-diethylphenyl)acetamide 0
                                        2-[2-(2-chlorophenyl)-1-benzimidazolyl]-N-(2-propan-2-ylphenyl)acetamide 0
                                        2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine 0
                                        2-[2-(ethylthio)-1-benzimidazolyl]-1-(1-piperidinyl)ethanone 0
                                        2-[2-[2-[(1,3-dimethyl-2-oxo-5-benzimidazolyl)methylidene]hydrazinyl]-4-oxo-5-thiazolyl]acetic acid 0
                                        2-[5-(4-carbamimidoylphenyl)furan-2-yl]-1H-benzimidazole-5-carboximidamide 0
                                        2-[5-[(5,7-dimethyl-1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid 0
                                        2-[5-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-furanyl]benzoic acid 0
                                        2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amine 0
                                        2-[[(1-butyl-2-benzimidazolyl)amino]methyl]phenol 0
                                        2-[[(1-propan-2-yl-2-benzimidazolyl)amino]methyl]-6-prop-2-enylphenol 0
                                        2-[[(6-bromo-1H-benzimidazol-2-yl)thio]methyl]-1-methylbenzimidazole 0
                                        2-[[2-(2-methylphenoxy)ethylthio]methyl]-1H-benzimidazole 0
                                        2-[[3-(1H-benzimidazol-2-yl)-2-pyridinyl]thio]acetic acid methyl ester 0
                                        2-[[5-(1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide 0
                                        2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(4-methyl-2-thiazolyl)acetamide 0
                                        2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamide 0
                                        2-[[5-[2-(1H-benzimidazol-2-yl)ethyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide 0
                                        2-[[5-[2-(1H-benzimidazol-2-yl)ethyl]-4-methyl-1,2,4-triazol-3-yl]thio]acetonitrile 0
                                        2-[[6-(butylsulfamoyl)-1H-benzimidazol-2-yl]thio]-N-(2-chlorophenyl)acetamide 0
                                        2-[[6-(dimethylsulfamoyl)-1H-benzimidazol-2-yl]methoxymethyl]-N,N-dimethyl-3H-benzimidazole-5-sulfonamide 0
                                        2-[[[2-methyl-1-(phenylmethyl)-5-benzimidazolyl]amino]methyl]phenol 0
                                        2-[[[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]methyl]benzonitrile 0
                                        2-[fluoro(trifluoromethoxy)methyl]-6-methyl-1H-benzimidazole 0
                                        2-aminobenzimidazole + 86
                                        2-benzamido-1-(3-phenylpropyl)-5-benzimidazolecarboxylic acid methyl ester 0
                                        2-ethyl-1-[(2-methoxyphenyl)methyl]benzimidazole 0
                                        2-ethyl-N-[1-[2-(1-piperidinyl)ethyl]-2-benzimidazolyl]-3-pyrazolecarboxamide 0
                                        2-methoxy-1-(1-methyl-2-benzimidazolyl)-1-phenylethanamine 0
                                        2-methoxy-N-[(1-methyl-2-benzimidazolyl)methyl]aniline 0
                                        2-methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(2-methoxyanilino)-2-oxoethyl] ester 0
                                        2-methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(3-methylbutan-2-ylamino)-2-oxoethyl] ester 0
                                        2-methyl-1H-benzimidazole-5-carboxylic acid 0
                                        2-methyl-1H-pyrimido[1,2-a]benzimidazol-4-one 0
                                        2-methyl-N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]propanamide 0
                                        2-methylpropanoic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester 0
                                        2-phenyl-2,3-dihydro-[1,3]thiazino[3,2-a]benzimidazol-4-one 0
                                        3,4,5-trimethoxy-N-[2-(1-methyl-2-benzimidazolyl)ethyl]benzamide 0
                                        3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol 0
                                        3,4-dimethyl-N-[[(2-oxo-1,3-dihydrobenzimidazol-5-yl)amino]-sulfanylidenemethyl]benzamide 0
                                        3-(1-benzimidazolylmethyl)-6-[(4-methoxyphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                                        3-(1H-benzimidazol-2-yl)-N-(3-pyridinylmethyl)aniline 0
                                        3-(1H-benzimidazol-2-ylthio)-5,5-dimethyl-3-(1-oxopropyl)-2-oxolanone 0
                                        3-(2-phenoxyethyl)-1H-benzimidazole-2-thione 0
                                        3-(6-amino-1H-benzimidazol-2-yl)-1-propanol 0
                                        3-(6-amino-1H-benzimidazol-2-yl)propanoic acid 0
                                        3-Hydroxyomeprazole 0
                                        3-[(7-carbamimidoylnaphthalen-2-yl)methyl]-5-(\{1-[(1Z)-ethanimidoyl]piperidin-4-yl\}oxy)-2-methyl-1H-3,1-benzimidazol-3-ium 0
                                        3-[1-(2-carboxyethyl)-1H-benzo[d]imidazol-2-yl]propanoic acid 0
                                        3-[1-[(4-methyl-6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-1H-benzimidazol-2-one 0
                                        3-[1-butyl-5-(diethylsulfamoyl)-2-benzimidazolyl]propanoic acid 0
                                        3-[2-(4-methyl-2-propan-2-ylphenoxy)ethyl]-1H-benzimidazole-2-thione 0
                                        3-[3-[[2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl]thio]propyl]-1H-benzimidazol-2-one 0
                                        3-[5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl]propan-1-ol 0
                                        3-[5-(diethylsulfamoyl)-1-methyl-2-benzimidazolyl]propanoic acid [2-(3,5-dichloroanilino)-2-oxoethyl] ester 0
                                        3-[5-(dimethylsulfamoyl)-1-ethyl-2-benzimidazolyl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)propanamide 0
                                        3-[5-(dimethylsulfamoyl)-1-ethyl-2-benzimidazolyl]propanoic acid 0
                                        3-\{[2-(1H-benzimidazol-1-yl)-6-\{[2-(diethylamino)ethyl]amino\}pyrimidin-4-yl]amino\}-4-methylphenol 0
                                        4,5,6,7-tetrabromobenzimidazole 0
                                        4-(1-ethyl-2-benzimidazolyl)aniline 0
                                        4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine 0
                                        4-(4-chloro-3-nitrophenyl)-N-[2-(5,6-dichloro-1-propyl-2-benzimidazolyl)ethyl]-2-thiazolamine 0
                                        4-(5,6-Dichloro-1H-benzimidazol-1-yl)butan-1-ol 0
                                        4-[(1H-benzimidazol-2-ylhydrazinylidene)methyl]benzoic acid 0
                                        4-[(1H-benzimidazol-2-ylthio)methyl]-2-thiazolamine 0
                                        4-[(6-chloro-1H-benzimidazol-2-yl)amino]benzoic acid 0
                                        4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine 0
                                        4-[1-[(3-methoxyphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine 0
                                        4-[2-(1-methyl-2-benzimidazolyl)ethyl]aniline 0
                                        4-[2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]-1-oxoethyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester 0
                                        4-[2-[[1-(phenylmethyl)-2-benzimidazolyl]thio]ethyl]morpholine 0
                                        4-[5-[(1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid 0
                                        4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-pyridinone 0
                                        4-[[2-(phenylmethyl)-1-benzimidazolyl]sulfonyl]morpholine 0
                                        4-ethyl-3-hydroxy-6-[5-methyl-4-(1-methyl-2-benzimidazolyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone 0
                                        4-methyl-N-[1-[2-(1-pyrrolidinyl)ethyl]-2-benzimidazolyl]benzamide 0
                                        4-oxo-10H-pyrimido[1,2-a]benzimidazole-3-carboxylic acid ethyl ester 0
                                        4H-[1,3]thiazino[3,2-a]benzimidazol-4-ol 0
                                        5'-O-Desmethyl omeprazole 0
                                        5'-hydroxyomeprazole 1
                                        5,6-dimethyl-1-octyl-4-benzimidazolamine 0
                                        5,6-dimethyl-2-[1-[[1-(phenylmethyl)-5-tetrazolyl]methyl]-4-piperidinyl]-1H-benzimidazole 0
                                        5,6-dimethyl-2-[2-(1-pyrrolidinyl)ethylthio]-1H-benzimidazole 0
                                        5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde 0
                                        5-(1H-benzimidazol-2-ylmethylidene)-3-(4-fluorophenyl)-2-sulfanylidene-4-thiazolidinone 0
                                        5-(2,3-dihydroindol-1-ylsulfonyl)-1,3-diethyl-2-benzimidazolone 0
                                        5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile 0
                                        5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(4-methylsulfonylphenyl)methoxy]-2-thiophenecarboxamide 0
                                        5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one 0
                                        5-Fluoro-2-[(3S)-1-(2-fluorobenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                                        5-Fluoro-2-[(3S)-1-(2-methylbenzyl)-3-pyrrolidinyl]-1H-benzimidazole 0
                                        5-Hydroxyemedastine 0
                                        5-Hydroxymebendazole 0
                                        5-Hydroxythiabendazole 0
                                        5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid 0
                                        5-[[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4-pyrazolylidene]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                                        5-[[3-bromo-4-[(2-fluorophenyl)methoxy]-5-methoxyphenyl]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                                        5-[[3-methyl-1-(4-methylphenyl)-5-oxo-4-pyrazolylidene]methylamino]-1,3-dihydrobenzimidazol-2-one 0
                                        5-[[4-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-ethoxyphenoxy]methyl]-2-furancarboxylic acid 0
                                        5-[[4-[2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-methoxyphenoxy]methyl]-2-furancarboxylic acid 0
                                        5-amino-4-(1H-benzimidazol-2-yl)-1-pentyl-2H-pyrrol-3-one 0
                                        5-amino-4-(1H-benzimidazol-2-yl)-1-propan-2-yl-2H-pyrrol-3-one 0
                                        5-chloro-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazole-2-thione 0
                                        5-ethoxy-2-[(2,3,4,5,6-pentafluorobenzyl)thio]-1H-benzo[d]imidazole 0
                                        5-hydroxybenzimidazole 0
                                        5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole + 411
                                        6-(1H-benzimidazol-2-yl)-2-methyl-1H-benzimidazole 0
                                        6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazole 0
                                        6-Hydroxyemedastine 0
                                        6-[3-[(2-hydroxyphenyl)methyl]-1H-benzimidazol-2-ylidene]-1-cyclohexa-2,4-dienone 0
                                        6-fluoro-2-[(6-fluoro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole 0
                                        6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole 0
                                        6-methyl-2-(trifluoromethyl)-3,5-dihydroimidazo[4,5-f]benzimidazole 0
                                        6-methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazole 0
                                        6-nitro-3-phenyl-1H-benzimidazole-2-thione 0
                                        6-nitro-8-(trifluoromethyl)benzo[4,5]imidazo[1,2-a]pyridine 0
                                        7-[[[1-(3-methylphenyl)-2-benzimidazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinone 0
                                        7-amino-N-cyclohexyl-1-methyl-2-thiazolo[3,2-a]benzimidazolecarboxamide 0
                                        7-amino-N-cyclohexyl-N,1-dimethyl-2-thiazolo[3,2-a]benzimidazolecarboxamide 0
                                        AZ3451 0
                                        Allyl 2-(1H-benzimidazoL-2-yl)-2-cyano-n-phenylethanimidothioate 0
                                        CGP 12177 10
                                        CHIR-265 0
                                        CHZ868 0
                                        Clemizole hydrochloride 0
                                        FIPI 0
                                        GSK461364 0
                                        GW843682X 0
                                        L-779976 0
                                        LSM-19079 0
                                        LSM-1988 0
                                        LSM-23645 0
                                        LSM-25679 0
                                        LSM-28507 0
                                        LSM-33057 0
                                        ML240 0
                                        Mizolastine 2
                                        N,N,1-triethyl-2-sulfanylidene-3H-benzimidazole-5-sulfonamide 0
                                        N,N,2-trimethyl-1-phenyl-5-benzimidazolesulfonamide 0
                                        N-(1,1-dioxo-3-thiolanyl)-N-methyl-2-[[1-(2-phenylethyl)-2-benzimidazolyl]thio]acetamide 0
                                        N-(1,3-dimethyl-2-oxo-5-benzimidazolyl)-2-benzofurancarboxamide 0
                                        N-(1-benzimidazolyl)-1-(6-chloro-5-imidazo[2,1-b]thiazolyl)methanimine 0
                                        N-(1-butyl-2-benzimidazolyl)cyclohexanecarboxamide 0
                                        N-(1-methyl-2-benzimidazolyl)-1-thiophen-2-ylmethanimine 0
                                        N-(1-propyl-5-benzimidazolyl)-2-thiophenecarboxamide 0
                                        N-(1-tert-butyl-5-benzimidazolyl)-2-thiophenecarboxamide 0
                                        N-(1-tert-butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide 0
                                        N-(1H-1,3-benzodiazol-2-yl)carbamate 0
                                        N-(1H-benzimidazol-2-yl)-2-methylsulfonylbenzamide 0
                                        N-(1H-benzimidazol-2-yl)-2-nitrobenzamide 0
                                        N-(1H-benzimidazol-2-yl)-3-(1-imidazolyl)propanamide 0
                                        N-(1H-benzimidazol-2-yl)-3-[(3-\{3-[(1H-benzimidazol-2-ylamino)carbonyl]benzyl\}-4,7-dibenzyl-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl)methyl]benzamide 0
                                        N-(1H-benzimidazol-2-yl)-3-phenylbutanamide 0
                                        N-(1H-benzimidazol-2-yl)-4-(3-methylphenoxy)butanamide 0
                                        N-(1H-benzimidazol-2-yl)carbamic acid ethyl ester 0
                                        N-(2-benzimidazolylidenemethyl)-1,2,4-triazol-4-amine 0
                                        N-(2-chlorobenzyl)-1-(2,5-dimethylphenyl)benzimidazole-5-carboxamide 0
                                        N-(2-ethoxyphenyl)-1H-benzimidazol-2-amine 0
                                        N-(2-fluorophenyl)-2-[2-(4-thiazolyl)-1-benzimidazolyl]acetamide 0
                                        N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolamine 0
                                        N-(2-methyl-1-benzimidazolyl)-1-(5-nitro-2-thiophenyl)methanimine 0
                                        N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)butanamide 0
                                        N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)pentanamide 0
                                        N-(3,5-dichloro-2-pyridinyl)-2-[(1-phenyl-2-benzimidazolyl)thio]acetamide 0
                                        N-(3,5-dichloro-2-pyridinyl)-2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]propanamide 0
                                        N-(3H-benzimidazol-5-yl)-2-furancarboxamide 0
                                        N-(4-methylphenyl)-5-nitro-4-spiro[benzimidazole-2,1'-cyclohexane]amine 0
                                        N-(5,6-dimethyl-1-benzimidazolyl)-1-(5-nitro-2-furanyl)methanimine 0
                                        N-(5-chloro-2-pyridinyl)-2-[[1-(2-methoxyethyl)-2-benzimidazolyl]thio]acetamide 0
                                        N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester 0
                                        N-(cyclohexylmethylideneamino)-1H-benzimidazol-2-amine 0
                                        N-[(1S)-1-(1H-benzimidazol-2-yl)-2-\{4-[(5S)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide 0
                                        N-[(1S)-1-(1H-benzimidazol-2-yl)-3-(methylthio)propyl]-2-(4-chlorophenoxy)-2-methylpropanamide 0
                                        N-[(3-methoxyphenyl)methyl]-1-propyl-5-benzimidazolamine 0
                                        N-[1-(1-hexyl-2-benzimidazolyl)ethyl]-2-furancarboxamide 0
                                        N-[1-(1H-benzimidazol-2-yl)-3-(methylthio)propyl]-3,5-dinitrobenzamide 0
                                        N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamide 0
                                        N-[1-(4-methylphenyl)-5-benzimidazolyl]acetamide 0
                                        N-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]-2-furancarboxamide 0
                                        N-[1-[1-[(3-chlorophenyl)methyl]-2-benzimidazolyl]ethyl]-3-(2-furanyl)-2-propenamide 0
                                        N-[1-[1-[2-[4-(diethylamino)anilino]-2-oxoethyl]-2-benzimidazolyl]ethyl]-4-methylbenzamide 0
                                        N-[1-[2-(1-piperidinyl)ethyl]-2-benzimidazolyl]-1-thiophen-2-ylmethanimine 0
                                        N-[1-[2-(2-chlorophenoxy)ethyl]-2-benzimidazolyl]acetamide 0
                                        N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide 0
                                        N-[2-(1H-benzimidazol-2-yl)ethyl]-3,5-dinitrobenzamide 0
                                        N-[2-(1H-benzimidazol-2-yl)phenyl]-2-thiophen-2-ylacetamide 0
                                        N-[2-(2-benzamidoethyl)-1-methyl-5-benzimidazolyl]-2-furancarboxamide 0
                                        N-[2-(2-benzamidoethyl)-1-methyl-5-benzimidazolyl]-2-methoxybenzamide 0
                                        N-[2-(2-pyridinyl)-3H-benzimidazol-5-yl]cyclohexanecarboxamide 0
                                        N-[2-(3-acetamidophenyl)-3H-benzimidazol-5-yl]acetamide 0
                                        N-[2-(3-pyridinyl)-3H-benzimidazol-5-yl]-2-furancarboxamide 0
                                        N-[2-(4-fluorophenyl)ethyl]-2-[2-(2-hydroxyethylamino)-1-benzimidazolyl]acetamide 0
                                        N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 0
                                        N-[2-[1-(3-phenylprop-2-enyl)-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                                        N-[2-[1-[2-(2,5-difluorophenoxy)ethyl]-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                                        N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]cycloheptanecarboxamide 0
                                        N-[2-[1-[2-(4-methylphenoxy)ethyl]-2-benzimidazolyl]ethyl]cyclohexanecarboxamide 0
                                        N-[2-[1-methyl-5-[[(4-methylphenyl)-oxomethyl]amino]-2-benzimidazolyl]ethyl]-2-furancarboxamide 0
                                        N-[2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-2-benzimidazol-3-iumyl]ethenyl]-N-methylaniline 0
                                        N-[3-(1H-benzimidazol-2-yl)-5-(1-piperazinylmethyl)phenyl]-2-quinoxalinecarboxamide 0
                                        N-[4-(1H-benzimidazol-2-yl)phenyl]-1-[(5-methyl-1H-pyrazol-3-yl)methyl]-3-piperidinecarboxamide 0
                                        N-[4-(1H-benzimidazol-2-yl)phenyl]-2,3,4,5,6-pentafluorobenzamide 0
                                        N-[4-(1H-benzimidazol-2-yl)phenyl]-2-methyl-4-nitro-3-pyrazolecarboxamide 0
                                        N-[4-(1H-benzimidazol-2-yl)phenyl]-3-(2,5-dioxo-1-pyrrolidinyl)benzamide 0
                                        N-[4-(1H-benzimidazol-2-yl)phenyl]-4-ethoxy-3-nitrobenzamide 0
                                        N-[4-(6-chloro-5-nitro-1H-benzimidazol-2-yl)phenyl]acetamide 0
                                        N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-2-(2-nitrophenoxy)acetamide 0
                                        N-[6-(propan-2-ylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester 0
                                        N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-2-[(1-ethyl-2-benzimidazolyl)thio]-N-methylacetamide 0
                                        N-[[1-(2-phenoxyethyl)-2-benzimidazolyl]methyl]aniline 0
                                        N-[[4-(diethylamino)phenyl]methyl]-1-[2-(1-piperidinyl)ethyl]-2-benzimidazolamine 0
                                        N-[[4-(dimethylamino)phenyl]methyl]-1-ethyl-5-benzimidazolamine 0
                                        N-[[5-(1H-benzimidazol-2-yl)-2-chloroanilino]-sulfanylidenemethyl]-2,6-dimethoxybenzamide 0
                                        N-[[5-(1H-benzimidazol-2-yl)-2-methylanilino]-sulfanylidenemethyl]-5-chloro-2-methoxybenzamide 0
                                        N-\{(1S)-2-\{4-[(5R)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]ethyl\}-2,2,2-trifluoroacetamide 0
                                        N-\{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl\}methanesulfonamide 0
                                        N-butyl-1H-benzimidazol-2-amine 0
                                        N-cycloheptyl-2-[(6-nitro-1H-benzimidazol-2-yl)thio]acetamide 0
                                        N-methyl-N-[(1-methyl-1H-benzimidazol-2-yl)methyl]amine 0
                                        N-phenyl-1-propan-2-yl-2-benzimidazolamine 0
                                        N2-(1H-benzimidazol-2-yl)benzene-1,2-diamine 0
                                        NNC 55-0396 (free base) + 0
                                        NS 1619 4
                                        NS-8593 0
                                        Omeprazole sodium 0
                                        Omeprazole sulfide 3
                                        Omeprazole sulfone 0
                                        Ro 18-5364 0
                                        ZSTK-474 0
                                        [1-(3-methylphenyl)-5-benzimidazolyl]-(1-piperidinyl)methanone 0
                                        [1-[3-(4-methylphenoxy)propyl]-2-benzimidazolyl]methanol 0
                                        [4-(2-benzimidazolylidene)-3-imino-2-phenyl-1H-pyridazin-6-yl]-thiophen-2-ylmethanone 0
                                        albendazole + 48
                                        astemizole 89
                                        azilsartan medoxomil 0
                                        bendamustine 0
                                        bendazol 0
                                        benomyl 59
                                        benzimidazole + 397
                                        benzimidazole fungicide + 451
                                        benzimidazolecarbaldehyde + 0
                                        benzimidazolecarboxylic acid + 80
                                        benzimidazolequinone + 0
                                        benzimidazolylcarbamate fungicide + 167
                                        bibenzimidazole + 6
                                        bilastine 0
                                        binimetinib 1
                                        carbendazim 86
                                        chlormidazole 6
                                        ciclobendazole 1
                                        clemizole 15
                                        crenolanib 0
                                        dabigatran + 28
                                        dabigatran etexilate 0
                                        desmethylastemizole 2
                                        dexlansoprazole 0
                                        dexrabeprazole 0
                                        dimethylbenzimidazole + 0
                                        domperidone + 20
                                        droperidol 2
                                        emedastine + 1
                                        ensulizole 0
                                        fabomotizole 0
                                        fenbendazole + 60
                                        flibanserin 0
                                        flubendazole 15
                                        fuberidazole 0
                                        glasdegib 0
                                        hydroxyalbendazole 0
                                        hydroxyfenbendazole 0
                                        ilaprazole 0
                                        lansoprazole 64
                                        liarozole 1
                                        magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide 0
                                        mebendazole 50
                                        methyl 4-oxo-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazine-2-carboxylate 0
                                        nocodazole 74
                                        oxatomide 4
                                        oxfendazole 19
                                        pantoprazole 32
                                        pantoprazole(1-) + 0
                                        parbendazole 1
                                        pimobendan 8
                                        pimozide 6
                                        procodazole 0
                                        rabeprazole 18
                                        selumetinib 29
                                        tarocin B 0
                                        tcmdc-123507 0
                                        telmisartan 122
                                        thiabendazole 338
                                        veliparib 30
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