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Gene: Proc (protein C) Mus musculus
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Symbol: Proc
Name: protein C
RGD ID: 11161
Description: Exhibits peptidase activity. Involved in liver development; negative regulation of blood coagulation; and regulation of circulating fibrinogen levels. Predicted to localize to Golgi apparatus; endoplasmic reticulum; and extracellular space. Is expressed in embryo; liver; and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including antiphospholipid syndrome; artery disease (multiple); placental abruption; protein C deficiency; and toxic shock syndrome. Orthologous to human PROC (protein C, inactivator of coagulation factors Va and VIIIa).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: anticoagulant protein C; autoprothrombin IIA; blood coagulation factor XIV; inactivator of coagulation factors Va, VIII; P; PC; vitamin K-dependent protein C
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1832,123,126 - 32,139,570 (-)EnsemblGRCm38mm10GRCm38
GRCm381832,123,126 - 32,139,570 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371832,282,780 - 32,299,224 (-)NCBIGRCm37mm9NCBIm37
MGSCv361832,266,137 - 32,278,949 (-)NCBImm8
Celera1832,604,740 - 32,621,169 (-)NCBICelera
Cytogenetic Map18B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Proc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11161
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.