H2-M2 (histocompatibility 2, M region locus 2) - Rat Genome Database

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Gene: H2-M2 (histocompatibility 2, M region locus 2) Mus musculus
Analyze
Symbol: H2-M2
Name: histocompatibility 2, M region locus 2
RGD ID: 1619261
MGI Page MGI
Description: Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Located in cell surface. Is expressed in several structures, including brain; genitourinary system; immune system; integument; and liver. Human ortholog(s) of this gene implicated in several diseases, including Stevens-Johnson syndrome; asthma (multiple); autoimmune disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-B (major histocompatibility complex, class I, B); HLA-C (major histocompatibility complex, class I, C); and HLA-E (major histocompatibility complex, class I, E).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: H-2M2; Thy19.4
RGD Orthologs
Human
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,791,742 - 37,794,445 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,791,742 - 37,794,443 (-)EnsemblGRCm39 Ensembl
GRCm381737,480,851 - 37,483,554 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,480,851 - 37,483,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,617,796 - 37,620,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361737,088,904 - 37,091,582 (-)NCBIMGSCv36mm8
Celera1740,921,406 - 40,924,072 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abacavir allergy  (ISO)
Acute Anterior Uveitis  (ISO)
acute retinal necrosis syndrome  (ISO)
allergic asthma  (ISO)
allergic disease  (ISO)
alopecia  (ISO)
ankylosing spondylitis  (ISO)
anterior uveitis  (ISO)
asthma  (ISO)
autism spectrum disorder  (ISO)
Behcet's disease  (ISO)
birdshot chorioretinopathy  (ISO)
cerebral infarction  (ISO)
cervical cancer  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (ISO)
colitis  (ISO)
COVID-19  (ISO)
cytomegalovirus retinitis  (ISO)
dermatitis  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
Diffuse Panbronchiolitis  (ISO)
drug allergy  (ISO)
Drug Eruptions  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Eales Disease  (ISO)
erythema nodosum  (ISO)
exanthem  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Genetic Predisposition to Disease  (ISO)
Graves' disease  (ISO)
Hearing Loss, Unilateral Sensorineural  (ISO)
high grade glioma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
megacolon  (ISO)
Meniere's disease  (ISO)
mitral valve prolapse  (ISO)
myasthenia gravis  (ISO)
Nasal Polyps  (ISO)
nephritis  (ISO)
occupational asthma  (ISO)
otosclerosis  (ISO)
Presumed Ocular Histoplasmosis Syndrome  (ISO)
proteasome-associated autoinflammatory syndrome 1  (ISO)
proteinuria  (ISO)
reactive arthritis  (ISO)
retinal vasculitis  (ISO)
retinopathy of prematurity  (ISO)
sarcoidosis  (ISO)
sensorineural hearing loss  (ISO)
severe acute respiratory syndrome  (ISO)
Spondylarthritis  (ISO)
spondyloarthropathy  (ISO)
Stevens-Johnson syndrome  (ISO)
synovitis  (ISO)
Takayasu's arteritis  (ISO)
thrombophlebitis  (ISO)
Thyrotoxic Periodic Paralysis  (ISO)
trachoma  (ISO)
Transplant Rejection  (ISO)
Trichiasis  (ISO)
tuberculosis  (ISO)
uveal melanoma  (ISO)
uveitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
abacavir  (EXP,ISO)
Aflatoxin G1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
allopurinol  (ISO)
amoxicillin  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
brinzolamide  (ISO)
butanal  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cefadroxil  (ISO)
chromium(6+)  (EXP)
chrysene  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
D-glucose  (EXP)
D-penicillamine  (ISO)
diarsenic trioxide  (ISO)
diltiazem  (ISO)
dimethylarsinic acid  (EXP)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
doxycycline  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
erythromycin A  (ISO)
ethylparaben  (ISO)
etoposide  (ISO)
eugenol  (ISO)
flucloxacillin  (ISO)
folic acid  (EXP)
fructose  (EXP)
furosemide  (ISO)
genistein  (EXP)
glucose  (EXP)
glyphosate  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydralazine  (ISO)
ifosfamide  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
lamotrigine  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (ISO)
lomefloxacin  (ISO)
methylarsonic acid  (EXP)
methylmercury chloride  (ISO)
metolazone  (ISO)
minocycline  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
ochratoxin A  (ISO)
omeprazole  (ISO)
oxcarbazepine  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
piroxicam  (ISO)
propanal  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetraphene  (EXP)
thimerosal  (ISO)
Tiopronin  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Association between human leukocyte antigen polymorphism and human papillomavirus 16-positive vulval intraepithelial neoplasia in British women. Davidson EJ, etal., Cancer Res. 2003 Jan 15;63(2):400-3.
2. HLA profile in patients with AIDS and tuberculosis. Figueiredo JF, etal., Braz J Infect Dis. 2008 Aug;12(4):278-80. doi: 10.1590/s1413-86702008000400004.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Allergic and Nonallergic Asthma Have Distinct Phenotypic and Genotypic Features. Takejima P, etal., Int Arch Allergy Immunol. 2017;172(3):150-160. doi: 10.1159/000458151. Epub 2017 Apr 6.
8. Genetic variants in the major histocompatibility complex class I and class II genes are associated with diisocyanate-induced Asthma. Yucesoy B, etal., J Occup Environ Med. 2014 Apr;56(4):382-7. doi: 10.1097/JOM.0000000000000138.
Additional References at PubMed
PMID:2573520   PMID:2793207   PMID:7665183   PMID:8367453   PMID:8406442   PMID:8833240   PMID:9185075   PMID:9510555   PMID:9570535   PMID:10458911   PMID:10495887   PMID:11173841  
PMID:12477932   PMID:15045471   PMID:18416856   PMID:21267068   PMID:21873635   PMID:33542915   PMID:35998585  


Genomics

Comparative Map Data
H2-M2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,791,742 - 37,794,445 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,791,742 - 37,794,443 (-)EnsemblGRCm39 Ensembl
GRCm381737,480,851 - 37,483,554 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,480,851 - 37,483,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,617,796 - 37,620,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361737,088,904 - 37,091,582 (-)NCBIMGSCv36mm8
Celera1740,921,406 - 40,924,072 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
HLA-B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,353,875 - 31,357,179 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,353,872 - 31,367,067 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,321,652 - 31,324,956 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,429,628 - 31,432,914 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,429,629 - 31,432,914NCBI
Celera632,921,554 - 32,924,897 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,112,051 - 31,115,393 (-)NCBIHuRef
CHM1_1631,323,557 - 31,326,920 (-)NCBICHM1_1
T2T-CHM13v2.0631,209,767 - 31,213,072 (-)NCBIT2T-CHM13v2.0
LOC100982859
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,922,418 - 45,926,176 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,883,973 - 41,887,389 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,106,562 - 31,109,933 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,996,784 - 32,000,234 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,997,381 - 32,000,067 (-)Ensemblpanpan1.1panPan2
DLA-64
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112983,573 - 986,969 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,119,986 - 1,123,382 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,128,741 - 1,132,125 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,078,335 - 1,172,648 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112987,659 - 991,030 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,056,161 - 1,059,718 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,122,932 - 1,126,491 (+)NCBIUU_Cfam_GSD_1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:344
Count of miRNA genes:224
Interacting mature miRNAs:235
Transcripts:ENSMUST00000016427, ENSMUST00000171139
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1301474Hcbip2_mhexachlorobenzene induced porphyria 2 (mouse)Not determined173779305545622654Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
D17Mit24  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381737,482,164 - 37,482,306UniSTSGRCm38
MGSCv371737,619,109 - 37,619,251UniSTSGRCm37
Celera1740,922,719 - 40,922,849UniSTS
Cytogenetic Map17B1UniSTS
cM Map1720.42UniSTS
Whitehead Genetic1710.9UniSTS
H2-M2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
cM Map1720.43UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001347387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH013247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL450393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY302217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M26156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000016427   ⟹   ENSMUSP00000016427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1737,791,742 - 37,794,442 (-)Ensembl
GRCm38.p6 Ensembl1737,480,851 - 37,483,551 (-)Ensembl
Ensembl Acc Id: ENSMUST00000171139   ⟹   ENSMUSP00000131297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1737,791,874 - 37,794,443 (-)Ensembl
GRCm38.p6 Ensembl1737,480,983 - 37,483,552 (-)Ensembl
RefSeq Acc Id: NM_001347387   ⟹   NP_001334316
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391737,791,742 - 37,794,445 (-)NCBI
GRCm381737,480,851 - 37,483,554 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001334316   ⟸   NM_001347387
- Peptide Label: precursor
- UniProtKB: Q6W9L1 (UniProtKB/TrEMBL),   Q6W9J9 (UniProtKB/TrEMBL),   Q6W9K4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000131297   ⟸   ENSMUST00000171139
Ensembl Acc Id: ENSMUSP00000016427   ⟸   ENSMUST00000016427
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6W9L1-F1-model_v2 AlphaFold Q6W9L1 1-343 view protein structure

Promoters
RGD ID:13676052
Promoter ID:EPDNEW_M22175
Type:initiation region
Name:H2-M2_1
Description:Mus musculus histocompatibility 2, M region locus 2 (H2-M2),mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381737,483,551 - 37,483,611EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95914 AgrOrtholog
Ensembl Genes ENSMUSG00000016283 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000016427.11 UniProtKB/TrEMBL
  ENSMUST00000171139 ENTREZGENE
  ENSMUST00000171139.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
KEGG Report mmu:14990 UniProtKB/TrEMBL
MGD MGI:95914 ENTREZGENE
NCBI Gene 14990 ENTREZGENE
PANTHER HISTOCOMPATIBILITY 2, M REGION LOCUS 2 UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/TrEMBL
PhenoGen H2-M2 PhenoGen
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt B2RWS1_MOUSE UniProtKB/TrEMBL
  Q6W9J6_MOUSE UniProtKB/TrEMBL
  Q6W9J7_MOUSE UniProtKB/TrEMBL
  Q6W9J8_MOUSE UniProtKB/TrEMBL
  Q6W9J9 ENTREZGENE, UniProtKB/TrEMBL
  Q6W9K4 ENTREZGENE, UniProtKB/TrEMBL
  Q6W9K6_MOUSE UniProtKB/TrEMBL
  Q6W9L1 ENTREZGENE, UniProtKB/TrEMBL