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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phloretin
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Accession:CHEBI:17276 term browser browse the term
Definition:A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
Synonyms:exact_synonym: 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
 related_synonym: 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone;   Formula=C15H14O5;   InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2;   InChIKey=VGEREEWJJVICBM-UHFFFAOYSA-N;   SMILES=Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
 alt_id: CHEBI:14787;   CHEBI:26014;   CHEBI:42649;   CHEBI:8111
 xref: CAS:60-82-2;   DrugBank:DB07810;   HMDB:HMDB0003306;   KEGG:C00774;   KNApSAcK:C00007936;   LINCS:LSM-6221;   LIPID_MAPS_instance:LMPK12120525
 xref_mesh: MESH:D010693
 xref: MetaCyc:PHLORETIN;   PDBeChem:G50;   PMID:18767070;   PMID:23907072;   PMID:24487097;   PMID:7126563;   Patent:CN102701938;   Patent:CN103230408;   Reaxys:1887240;   Wikipedia:Phloretin


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phloretin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Phloretin] results in increased activity of ACHE protein; [coenzyme Q10 co-treated with biochanin A co-treated with Phloretin] inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of ACHE protein]; Phloretin inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of ACHE protein] CTD PMID:33410021 PMID:35547012 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased secretion of ADIPOQ protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ADIPOQ mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of ADIPOQ mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased secretion of ADIPOQ protein] CTD PMID:32408695 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Afp alpha fetoprotein affects binding ISO Phloretin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO [Ruthenium binds to Phloretin] which results in decreased expression of AKT1 protein
Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of AKT1 mRNA]		 CTD PMID:34037972 PMID:34896434 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ANGPTL4 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of ANGPTL4 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ANGPTL4 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of ANGPTL4 mRNA CTD PMID:32408695 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804 		JBrowse link
G Aqp9 aquaporin 9 multiple interactions
decreases activity		 ISO Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]
Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenic Acid analog]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid]
Phloretin results in decreased activity of AQP9 protein		 CTD PMID:9733774 PMID:12606488 PMID:21259319 PMID:28798983 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] CTD PMID:32408695 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA] CTD PMID:34037972 PMID:34896434 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP [coenzyme Q10 co-treated with biochanin A co-treated with Phloretin] inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of BCHE protein]; Phloretin inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of BCHE protein]; Phloretin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of BCHE protein] CTD PMID:33410021 PMID:35547012 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA] CTD PMID:34037972 PMID:34896434 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] CTD PMID:32408695 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions EXP Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BCL2L11 protein] CTD PMID:32408695 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Ruthenium binds to Phloretin] which results in increased cleavage of CASP3 protein CTD PMID:34896434 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Ruthenium binds to Phloretin] which results in decreased expression of and results in increased cleavage of CASP9 protein CTD PMID:34896434 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein] CTD PMID:34896434 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cav3 caveolin 3 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of CAV3 mRNA] CTD PMID:34037972 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP		 Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]
Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of CCL2 protein]
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of CCL2 mRNA		 CTD PMID:24707119 PMID:32408695 PMID:34037972 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein] CTD PMID:24707119 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO [Ruthenium binds to Phloretin] which results in increased expression of CDKN1A protein CTD PMID:34896434 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions ISO Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] CTD PMID:24707119 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:17177569 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Des desmin multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of DES mRNA] CTD PMID:34037972 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein CTD PMID:34896434 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Phloretin binds to and results in increased activity of ESR1 protein CTD PMID:9751507 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
affects binding		 ISO Phloretin binds to and results in increased activity of ESR2 protein
Phloretin binds to ESR2 protein		 CTD PMID:9751507 PMID:12224631 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP Phloretin inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:30287234 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity ISO Phloretin results in decreased activity of GSK3B protein CTD PMID:16968061 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of HIF1A mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of HIF1A mRNA CTD PMID:32408695 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]
Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IFNG protein]		 CTD PMID:24707119 PMID:34037972 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of IGF1 mRNA] CTD PMID:34037972 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of IL10 protein]		 CTD PMID:24707119 PMID:34037972 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:24707119 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 Phloretin inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL1B mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of IL1B mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL1B mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL1B mRNA		 CTD PMID:21051542 PMID:32408695 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1RN protein] CTD PMID:24707119 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IL2 protein] CTD PMID:34037972 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL6 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL6 mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]		 CTD PMID:24707119 PMID:32408695 PMID:34037972 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ins2 insulin II multiple interactions ISO Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] CTD PMID:17965850 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 affects response to substance ISO KCNMA1 mRNA affects the susceptibility to Phloretin CTD PMID:19247476 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559 		JBrowse link
G Lep leptin multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of LEP mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of LEP mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of LEP mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of LEP mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of LEP mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of LEP mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of LEP protein] CTD PMID:32408695 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Ltf lactotransferrin increases expression ISO Phloretin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of MAPK1 mRNA] CTD PMID:34037972 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of MAPK3 mRNA] CTD PMID:34037972 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK8 mRNA] CTD PMID:34037972 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MKI67 protein] CTD PMID:34896434 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP9 protein] CTD PMID:34896434 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Ruthenium binds to Phloretin] which results in decreased expression of MTOR protein CTD PMID:34896434 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of NFATC1 mRNA]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of NFATC1 protein] CTD PMID:34037972 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions EXP [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Phloretin] results in increased expression of NFE2L2 mRNA CTD PMID:33410021 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of NFKB1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of NFKB1 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of NFKB1 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of NFKB1 mRNA CTD PMID:32408695 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell decreases expression
multiple interactions		 ISO Phloretin results in decreased expression of NOS3 mRNA
Phloretin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]		 CTD PMID:20021702 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of PPARG mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNA CTD PMID:32408695 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of PPP3CA protein] CTD PMID:34037972 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions ISO Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of RAF1 mRNA] CTD PMID:34037972 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]
Phloretin inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]		 CTD PMID:32408695 PMID:34037972 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO Phloretin binds to SHBG protein CTD PMID:25349334 NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731 		JBrowse link
G Slc14a1 solute carrier family 14 (urea transporter), member 1 multiple interactions ISO Phloretin inhibits the reaction [SLC14A1 protein results in increased transport of Urea] CTD PMID:8982255 NCBI chr18:78,143,306...78,185,334
Ensembl chr18:78,143,306...78,185,334 		JBrowse link
G Slc14a2 solute carrier family 14 (urea transporter), member 2 multiple interactions ISO Phloretin inhibits the reaction [SLC14A2 protein results in increased transport of Urea] CTD PMID:11181411 NCBI chr18:78,189,359...78,640,165
Ensembl chr18:78,189,363...78,640,157 		JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions ISO [[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate; [Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate CTD PMID:17108059 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778 		JBrowse link
G Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 multiple interactions ISO Phloretin inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:102,741,020...102,865,594
Ensembl chr  X:102,741,020...102,865,589 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions
decreases activity		 ISO Phloretin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
Phloretin results in decreased activity of SLC2A1 protein		 CTD PMID:14642735 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions
decreases expression		 EXP
ISO		 Phloretin inhibits the reaction [Fluorouracil promotes the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]]; Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]
Phloretin results in decreased expression of SLC2A2 protein
Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose]		 CTD PMID:15986457 PMID:17272349 PMID:26616219 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9 multiple interactions EXP Phloretin inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] CTD PMID:19587147 NCBI chr 5:38,506,616...38,660,488
Ensembl chr 5:38,506,616...38,660,486 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 multiple interactions
decreases activity		 ISO Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]]
Phloretin results in decreased activity of SLC9A1 protein; Phloretin results in decreased activity of SLC9A1 protein alternative form		 CTD PMID:12765964 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G Slc9b2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 decreases activity ISO Phloretin results in decreased activity of SLC9B2 protein CTD PMID:18000046 NCBI chr 3:135,013,083...135,048,606
Ensembl chr 3:135,013,461...135,051,148 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of TNF mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of TNF mRNA
Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]		 CTD PMID:32408695 PMID:34037972 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein]
[Ruthenium binds to Phloretin] which results in increased expression of TP53 protein		 CTD PMID:34896434 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases activity ISO Phloretin results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation
decreases activity		 ISO UGT1A10 protein results in increased glucuronidation of Phloretin
Phloretin results in decreased activity of UGT1A10 protein		 CTD PMID:14557274 PMID:35868516 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO Phloretin results in decreased activity of UGT1A3 protein CTD PMID:35868516 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B decreases activity ISO Phloretin results in decreased activity of UGT1A6 protein CTD PMID:35868516 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases activity ISO Phloretin results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO Phloretin results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 decreases activity ISO Phloretin results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP
ISO		 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of VEGFA protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of VEGFA mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of VEGFA mRNA; Phloretin promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of VEGFA protein]
[Ruthenium binds to Phloretin] which results in decreased expression of VEGFA protein		 CTD PMID:32408695 PMID:34896434 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
phlorizin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase decreases expression EXP Phlorhizin results in decreased expression of ABAT mRNA CTD PMID:22538082 NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression EXP Phlorhizin results in increased expression of ACAA1 mRNA CTD PMID:22538082 NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression EXP Phlorhizin results in decreased expression of ACAA2 mRNA CTD PMID:22538082 NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279 		JBrowse link
G Acad8 acyl-Coenzyme A dehydrogenase family, member 8 decreases expression EXP Phlorhizin results in decreased expression of ACAD8 mRNA CTD PMID:22538082 NCBI chr 9:26,885,434...26,910,872
Ensembl chr 9:26,885,431...26,910,862 		JBrowse link
G Acad9 acyl-Coenzyme A dehydrogenase family, member 9 decreases expression EXP Phlorhizin results in decreased expression of ACAD9 mRNA CTD PMID:22538082 NCBI chr 3:36,120,128...36,147,006
Ensembl chr 3:36,120,128...36,147,002 		JBrowse link
G Acadl acyl-Coenzyme A dehydrogenase, long-chain decreases expression EXP Phlorhizin results in decreased expression of ACADL mRNA CTD PMID:22538082 NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436 		JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain decreases expression EXP Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269 		JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 decreases expression EXP Phlorhizin results in decreased expression of ACAT1 mRNA CTD PMID:22538082 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Aco1 aconitase 1 decreases expression EXP Phlorhizin results in decreased expression of ACO1 mRNA CTD PMID:22538082 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl decreases expression EXP Phlorhizin results in decreased expression of ACOX1 mRNA CTD PMID:22538082 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Acox2 acyl-Coenzyme A oxidase 2, branched chain decreases expression EXP Phlorhizin results in decreased expression of ACOX2 mRNA CTD PMID:22538082 NCBI chr14:14,210,406...14,244,262
Ensembl chr14:14,210,420...14,244,262 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP Phlorhizin results in decreased expression of ACSL1 mRNA CTD PMID:22538082 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088 		JBrowse link
G Actb actin, beta increases expression EXP Phlorhizin results in increased expression of ACTB mRNA CTD PMID:22538082 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression EXP Phlorhizin results in decreased expression of ADH5 mRNA CTD PMID:22538082 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP Phlorhizin results in decreased expression of ADHFE1 mRNA CTD PMID:22538082 NCBI chr 1:9,618,173...9,648,195
Ensembl chr 1:9,618,173...9,650,898 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA CTD PMID:32408695 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 decreases expression EXP Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 increases expression EXP Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737 		JBrowse link
G Alb albumin multiple interactions ISO Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] CTD PMID:16313995 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 decreases expression EXP Phlorhizin results in decreased expression of ALDH1A7 mRNA CTD PMID:22538082 NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases expression
increases expression		 EXP Phlorhizin results in decreased expression of ALDH2 mRNA
Phlorhizin results in increased expression of ALDH2 mRNA		 CTD PMID:22538082 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 decreases expression EXP Phlorhizin results in decreased expression of ALDH3A2 mRNA CTD PMID:22538082 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290 		JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH4A1 mRNA CTD PMID:22538082 NCBI chr 4:139,348,404...139,377,002
Ensembl chr 4:139,350,177...139,377,001 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH6A1 mRNA CTD PMID:22538082 NCBI chr12:84,477,491...84,497,798
Ensembl chr12:84,477,491...84,497,778 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 decreases expression EXP Phlorhizin results in decreased expression of ALDH7A1 mRNA CTD PMID:22538082 NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 decreases expression EXP Phlorhizin results in decreased expression of ANAPC2 mRNA CTD PMID:22538082 NCBI chr 2:25,162,469...25,175,928
Ensembl chr 2:25,162,490...25,175,927 		JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 decreases expression EXP Phlorhizin results in decreased expression of ANAPC5 mRNA CTD PMID:22538082 NCBI chr 5:122,925,522...122,960,402
Ensembl chr 5:122,925,522...122,959,402 		JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression EXP Phlorhizin results in decreased expression of AOX1 mRNA CTD PMID:22538082 NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572 		JBrowse link
G Aox3 aldehyde oxidase 3 decreases expression EXP Phlorhizin results in decreased expression of AOX3 mRNA CTD PMID:22538082 NCBI chr 1:58,152,294...58,241,380
Ensembl chr 1:58,152,289...58,239,857 		JBrowse link
G Aph1b aph1 homolog B, gamma secretase subunit increases expression EXP Phlorhizin results in increased expression of APH1B mRNA CTD PMID:22538082 NCBI chr 9:66,682,484...66,704,671
Ensembl chr 9:66,682,484...66,702,772 		JBrowse link
G App amyloid beta precursor protein decreases expression EXP Phlorhizin results in decreased expression of APP mRNA CTD PMID:22538082 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Atf3 activating transcription factor 3 decreases expression EXP Phlorhizin results in decreased expression of ATF3 mRNA CTD PMID:16123366 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 increases expression EXP Phlorhizin results in increased expression of ATP2A2 mRNA CTD PMID:16123366 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression EXP Phlorhizin results in decreased expression of ATP5F1A mRNA CTD PMID:22538082 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma increases expression EXP Phlorhizin results in increased expression of ATP5F1C mRNA CTD PMID:22538082 NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321 		JBrowse link
G Auh AU RNA binding protein/enoyl-coenzyme A hydratase decreases expression EXP Phlorhizin results in decreased expression of AUH mRNA CTD PMID:22538082 NCBI chr13:52,989,155...53,083,742
Ensembl chr13:52,989,155...53,083,717 		JBrowse link
G B2m beta-2 microglobulin increases expression EXP Phlorhizin results in increased expression of B2M mRNA CTD PMID:22538082 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] CTD PMID:32408695 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bag1 BCL2-associated athanogene 1 decreases expression EXP Phlorhizin results in decreased expression of BAG1 mRNA CTD PMID:22538082 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294 		JBrowse link
G Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide decreases expression EXP Phlorhizin results in decreased expression of BCKDHB mRNA CTD PMID:22538082 NCBI chr 9:83,807,190...84,006,293
Ensembl chr 9:83,807,198...84,006,293 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions EXP [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] CTD PMID:32408695 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression EXP Phlorhizin results in increased expression of BIRC6 mRNA CTD PMID:22538082 NCBI chr17:74,835,247...75,010,351
Ensembl chr17:74,835,290...75,010,351 		JBrowse link
G Cat catalase increases expression EXP Phlorhizin results in increased expression of CAT mRNA CTD PMID:22538082 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA CTD PMID:32408695 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression EXP Phlorhizin results in decreased expression of CCT7 mRNA CTD PMID:22538082 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] CTD PMID:18715473 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349 		JBrowse link
G Clybl citrate lyase beta like decreases expression EXP Phlorhizin results in decreased expression of CLYBL mRNA CTD PMID:22538082 NCBI chr14:122,408,289...122,639,646
Ensembl chr14:122,419,116...122,639,646 		JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 decreases expression EXP Phlorhizin results in decreased expression of COX15 mRNA CTD PMID:22538082 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439 		JBrowse link
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone decreases expression EXP Phlorhizin results in decreased expression of COX17 mRNA CTD PMID:22538082 NCBI chr16:38,167,332...38,173,125
Ensembl chr16:38,167,353...38,182,659 		JBrowse link
G Cox7c cytochrome c oxidase subunit 7C increases expression EXP Phlorhizin results in increased expression of COX7C mRNA CTD PMID:22538082 NCBI chr13:86,192,917...86,194,914
Ensembl chr13:86,192,935...86,195,023 		JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression EXP Phlorhizin results in decreased expression of COX8A mRNA CTD PMID:22538082 NCBI chr19:7,192,523...7,194,981
Ensembl chr19:7,192,518...7,194,981 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver decreases expression EXP Phlorhizin results in decreased expression of CPT1A mRNA CTD PMID:16123366 PMID:22538082 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression EXP Phlorhizin results in decreased expression of CPT2 mRNA CTD PMID:22538082 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807 		JBrowse link
G Crebbp CREB binding protein decreases expression EXP Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Cs citrate synthase decreases expression EXP Phlorhizin results in decreased expression of CS mRNA CTD PMID:22538082 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Cul1 cullin 1 decreases expression EXP Phlorhizin results in decreased expression of CUL1 mRNA CTD PMID:22538082 NCBI chr 6:47,430,516...47,503,078
Ensembl chr 6:47,430,332...47,503,073 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP Phlorhizin results in decreased expression of CYB5R3 mRNA CTD PMID:22538082 NCBI chr15:83,037,696...83,060,641
Ensembl chr15:83,037,695...83,056,793 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP Phlorhizin results in decreased expression of CYP1A2 mRNA CTD PMID:22538082 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases expression EXP Phlorhizin results in decreased expression of CYP2B6 mRNA CTD PMID:22538082 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2d13 cytochrome P450, family 2, subfamily d, polypeptide 13 decreases expression EXP Phlorhizin results in decreased expression of CYP2D13 mRNA CTD PMID:22538082 NCBI chr15:82,520,951...82,526,246
Ensembl chr15:82,520,388...82,526,247 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases expression EXP Phlorhizin results in increased expression of CYP2D6 mRNA CTD PMID:22538082 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5 decreases expression EXP Phlorhizin results in decreased expression of CYP2J5 mRNA CTD PMID:22538082 NCBI chr 4:96,517,010...96,552,391
Ensembl chr 4:96,517,010...96,552,391 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases expression
increases expression		 EXP Phlorhizin results in decreased expression of CYP3A7 mRNA
Phlorhizin results in increased expression of CYP3A7 mRNA		 CTD PMID:22538082 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 increases expression EXP Phlorhizin results in increased expression of CYP4A11 mRNA CTD PMID:22538082 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846 		JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 decreases expression EXP Phlorhizin results in decreased expression of CYP4F12 mRNA CTD PMID:22538082 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 decreases expression EXP Phlorhizin results in decreased expression of DHRS4 mRNA CTD PMID:22538082 NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797 		JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of DLD mRNA CTD PMID:22538082 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452 		JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression EXP Phlorhizin results in decreased expression of DNAJA2 mRNA CTD PMID:22538082 NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression EXP Phlorhizin results in decreased expression of DNAJA3 mRNA CTD PMID:22538082 NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
increases expression		 EXP Phlorhizin results in decreased expression of DNAJB1 mRNA
Phlorhizin results in increased expression of DNAJB1 mRNA		 CTD PMID:22538082 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression EXP Phlorhizin results in decreased expression of DNAJB4 mRNA CTD PMID:22538082 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression EXP Phlorhizin results in increased expression of DNAJB6 mRNA CTD PMID:22538082 NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132 		JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression EXP Phlorhizin results in decreased expression of DNAJC1 mRNA CTD PMID:22538082 NCBI chr 2:18,210,445...18,402,025
Ensembl chr 2:18,200,465...18,397,641 		JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression EXP Phlorhizin results in decreased expression of DNAJC13 mRNA CTD PMID:22538082 NCBI chr 9:104,028,796...104,140,807
Ensembl chr 9:104,028,481...104,140,129 		JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 increases expression EXP Phlorhizin results in increased expression of DNAJC14 mRNA CTD PMID:22538082 NCBI chr10:128,641,423...128,655,317
Ensembl chr10:128,639,931...128,655,315 		JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression EXP Phlorhizin results in decreased expression of DNAJC19 mRNA CTD PMID:22538082 NCBI chr 3:34,111,429...34,135,503
Ensembl chr 3:34,110,169...34,135,470 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression EXP Phlorhizin results in decreased expression of DNAJC3 mRNA CTD PMID:22538082 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109 		JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 increases expression EXP Phlorhizin results in increased expression of DNAJC4 mRNA CTD PMID:22538082 NCBI chr19:6,965,279...6,969,954
Ensembl chr19:6,965,279...6,969,940 		JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression EXP Phlorhizin results in decreased expression of DNAJC5 mRNA CTD PMID:22538082 NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926 		JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial decreases expression EXP Phlorhizin results in decreased expression of ECHS1 mRNA CTD PMID:22538082 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389 		JBrowse link
G Ep300 E1A binding protein p300 decreases expression EXP Phlorhizin results in decreased expression of EP300 mRNA CTD PMID:22538082 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal decreases expression EXP Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Phlorhizin results in decreased expression of FAS mRNA CTD PMID:16123366 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 decreases expression EXP Phlorhizin results in decreased expression of FBXW7 mRNA CTD PMID:22538082 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505 		JBrowse link
G Fh1 fumarate hydratase 1 decreases expression EXP Phlorhizin results in decreased expression of FH mRNA CTD PMID:22538082 NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201 		JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Phlorhizin results in increased expression of FIS1 mRNA CTD PMID:22538082 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Fkbp5 FK506 binding protein 5 decreases expression EXP Phlorhizin results in decreased expression of FKBP5 mRNA CTD PMID:22538082 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501 		JBrowse link
G Fmo1 flavin containing monooxygenase 1 decreases expression EXP Phlorhizin results in decreased expression of FMO1 mRNA CTD PMID:22538082 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] CTD PMID:12446591 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Phlorhizin results in decreased expression of GCLC mRNA CTD PMID:22538082 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit decreases expression EXP Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Glrx2 glutaredoxin 2 decreases expression EXP Phlorhizin results in decreased expression of GLRX2 mRNA CTD PMID:22538082 NCBI chr 1:143,614,787...143,625,416
Ensembl chr 1:143,592,076...143,625,414 		JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial increases expression
decreases expression		 EXP Phlorhizin results in increased expression of GPD2 mRNA
Phlorhizin results in decreased expression of GPD2 mRNA		 CTD PMID:16123366 PMID:22538082 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Phlorhizin results in decreased expression of GPX1 mRNA CTD PMID:16123366 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression EXP Phlorhizin results in increased expression of GPX7 mRNA CTD PMID:22538082 NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) decreases expression EXP Phlorhizin results in decreased expression of GSTA5 mRNA CTD PMID:22538082 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression EXP Phlorhizin results in decreased expression of GSTK1 mRNA CTD PMID:22538082 NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression EXP Phlorhizin results in decreased expression of GSTM1 mRNA CTD PMID:22538082 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression
decreases expression		 EXP Phlorhizin results in increased expression of GSTM2 mRNA; Phlorhizin results in increased expression of GSTM5 mRNA
Phlorhizin results in decreased expression of GSTM5 mRNA		 CTD PMID:22538082 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
G Gstm4 glutathione S-transferase, mu 4 increases expression EXP Phlorhizin results in increased expression of GSTM4 mRNA CTD PMID:22538082 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression EXP Phlorhizin results in increased expression of GSTP1 mRNA CTD PMID:22538082 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 decreases expression
increases expression		 EXP Phlorhizin results in decreased expression of GSTT1 mRNA
Phlorhizin results in increased expression of GSTT1 mRNA		 CTD PMID:22538082 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression EXP Phlorhizin results in decreased expression of GSTT2B mRNA CTD PMID:22538082 NCBI chr10:75,667,676...75,673,253
Ensembl chr10:75,666,948...75,673,258 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP Phlorhizin results in decreased expression of HACD3 mRNA CTD PMID:22538082 NCBI chr 9:64,894,265...64,929,014
Ensembl chr 9:64,894,265...64,928,975 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP Phlorhizin results in increased expression of HADHB mRNA CTD PMID:22538082 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591 		JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 decreases expression EXP Phlorhizin results in decreased expression of HERPUD1 mRNA CTD PMID:22538082 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of HIBADH mRNA CTD PMID:22538082 NCBI chr 6:52,523,215...52,617,285
Ensembl chr 6:52,523,213...52,617,374 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression EXP Phlorhizin results in decreased expression of HMGCS1 mRNA CTD PMID:22538082 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Phlorhizin results in decreased expression of HMOX1 mRNA CTD PMID:16123366 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases expression EXP Phlorhizin results in increased expression of HRAS mRNA CTD PMID:22538082 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression EXP Phlorhizin results in decreased expression of HSD17B10 mRNA CTD PMID:22538082 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression EXP Phlorhizin results in decreased expression of HSD17B4 mRNA CTD PMID:22538082 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 decreases expression EXP Phlorhizin results in decreased expression of HSP90AA1 mRNA CTD PMID:22538082 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 decreases expression EXP Phlorhizin results in decreased expression of HSP90AB1 mRNA CTD PMID:22538082 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197 		JBrowse link
G Hspa13 heat shock protein 70 family, member 13 decreases expression EXP Phlorhizin results in decreased expression of HSPA13 mRNA CTD PMID:22538082 NCBI chr16:75,552,078...75,564,575
Ensembl chr16:75,542,319...75,563,992 		JBrowse link
G Hspa5 heat shock protein 5 increases expression EXP Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa8 heat shock protein 8 increases expression EXP Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hspa9 heat shock protein 9 decreases expression EXP Phlorhizin results in decreased expression of HSPA9 mRNA CTD PMID:22538082 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspb1 heat shock protein 1 increases expression EXP Phlorhizin results in increased expression of HSPB1 mRNA CTD PMID:22538082 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hspb8 heat shock protein 8 decreases expression EXP Phlorhizin results in decreased expression of HSPB8 mRNA CTD PMID:22538082 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression EXP Phlorhizin results in decreased expression of HSPD1 mRNA CTD PMID:22538082 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) decreases expression EXP Phlorhizin results in decreased expression of HSPE1 mRNA CTD PMID:22538082 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466 		JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression EXP Phlorhizin results in decreased expression of HTRA2 mRNA CTD PMID:22538082 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression EXP Phlorhizin results in decreased expression of ID1 mRNA CTD PMID:16123366 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial increases expression EXP Phlorhizin results in increased expression of IDH2 mRNA CTD PMID:22538082 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140 		JBrowse link
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha decreases expression EXP Phlorhizin results in decreased expression of IDH3A mRNA CTD PMID:22538082 NCBI chr 9:54,493,795...54,511,946
Ensembl chr 9:54,493,618...54,511,945 		JBrowse link
G Idh3b isocitrate dehydrogenase 3 (NAD+) beta decreases expression EXP Phlorhizin results in decreased expression of IDH3B mRNA CTD PMID:22538082 NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467 		JBrowse link
G Idh3g isocitrate dehydrogenase 3 (NAD+), gamma decreases expression EXP Phlorhizin results in decreased expression of IDH3G mRNA CTD PMID:22538082 NCBI chr  X:72,822,569...72,830,471
Ensembl chr  X:72,822,569...72,830,503 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL1B mRNA CTD PMID:32408695 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA CTD PMID:32408695 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ivd isovaleryl coenzyme A dehydrogenase decreases expression EXP Phlorhizin results in decreased expression of IVD mRNA CTD PMID:22538082 NCBI chr 2:118,692,475...118,713,388
Ensembl chr 2:118,692,435...118,713,390 		JBrowse link
G Junb jun B proto-oncogene decreases expression EXP Phlorhizin results in decreased expression of JUNB mRNA CTD PMID:22538082 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347 		JBrowse link
G Jund jun D proto-oncogene increases expression EXP Phlorhizin results in increased expression of JUND mRNA CTD PMID:22538082 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 increases expression EXP Phlorhizin results in increased expression of KCNJ11 mRNA CTD PMID:16123366 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 increases expression EXP Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog decreases expression EXP Phlorhizin results in decreased expression of KRAS mRNA CTD PMID:22538082 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lep leptin multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA]; [2,2-bis(4-glycidyloxyphenyl)propane co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of LEP mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA CTD PMID:32408695 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Maf MAF bZIP transcription factor decreases expression EXP Phlorhizin results in decreased expression of MAF mRNA CTD PMID:22538082 NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533 		JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) decreases expression EXP Phlorhizin results in decreased expression of MAFG mRNA CTD PMID:22538082 NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426 		JBrowse link
G Maob monoamine oxidase B decreases expression EXP Phlorhizin results in decreased expression of MAOB mRNA CTD PMID:22538082 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 increases expression EXP Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression EXP Phlorhizin results in increased expression of MAP2K6 mRNA CTD PMID:22538082 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 increases expression EXP Phlorhizin results in increased expression of MAP2K7 mRNA CTD PMID:22538082 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 decreases expression EXP Phlorhizin results in decreased expression of MAP3K7 mRNA CTD PMID:22538082 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases expression EXP Phlorhizin results in increased expression of MAPK3 mRNA CTD PMID:22538082 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression EXP Phlorhizin results in decreased expression of MAPK9 mRNA CTD PMID:22538082 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) decreases expression EXP Phlorhizin results in decreased expression of MCCC2 mRNA CTD PMID:22538082 NCBI chr13:100,085,040...100,152,147
Ensembl chr13:100,085,038...100,152,147 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression EXP Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Med20 mediator complex subunit 20 decreases expression EXP Phlorhizin results in decreased expression of MED20 mRNA CTD PMID:22538082 NCBI chr17:47,922,510...47,935,176
Ensembl chr17:47,922,507...47,935,343 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression EXP Phlorhizin results in increased expression of MGST1 mRNA CTD PMID:22538082 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753 		JBrowse link
G Mmut methylmalonyl-Coenzyme A mutase decreases expression EXP Phlorhizin results in decreased expression of MMUT mRNA CTD PMID:22538082 NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879 		JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory decreases phosphorylation ISO Phlorhizin results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578 		JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 increases expression EXP Phlorhizin results in increased expression of NDUFA12 mRNA CTD PMID:22538082 NCBI chr10:94,034,897...94,057,302
Ensembl chr10:94,034,582...94,057,305 		JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 increases expression EXP Phlorhizin results in increased expression of NDUFA2 mRNA CTD PMID:22538082 NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression EXP Phlorhizin results in decreased expression of NDUFA3 mRNA CTD PMID:22538082 NCBI chr 7:3,620,372...3,623,162
Ensembl chr 7:3,620,372...3,623,326 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP Phlorhizin results in increased expression of NDUFA7 mRNA CTD PMID:22538082 NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP Phlorhizin results in increased expression of NDUFAB1 mRNA CTD PMID:22538082 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109 		JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression EXP Phlorhizin results in decreased expression of NDUFAF1 mRNA CTD PMID:22538082 NCBI chr 2:119,485,927...119,493,302
Ensembl chr 2:119,485,927...119,493,308 		JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression EXP Phlorhizin results in decreased expression of NDUFB6 mRNA CTD PMID:22538082 NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression EXP Phlorhizin results in decreased expression of NDUFS1 mRNA CTD PMID:22538082 NCBI chr 1:63,182,751...63,215,981
Ensembl chr 1:63,182,755...63,215,992 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 decreases expression EXP Phlorhizin results in decreased expression of NDUFS4 mRNA CTD PMID:22538082 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794 		JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 decreases expression EXP Phlorhizin results in decreased expression of NDUFS5 mRNA CTD PMID:22538082 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression EXP Phlorhizin results in increased expression of NDUFS8 mRNA CTD PMID:22538082 NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774 		JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 decreases expression EXP Phlorhizin results in decreased expression of NEDD4 mRNA CTD PMID:22538082 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134 		JBrowse link
G Neurod1 neurogenic differentiation 1 increases expression EXP Phlorhizin results in increased expression of NEUROD1 mRNA CTD PMID:16123366 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression EXP Phlorhizin results in decreased expression of NFE2L2 mRNA CTD PMID:22538082 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP [Phlorhizin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane co-treated with cobaltous chloride] affects the expression of NFKB1 mRNA CTD PMID:32408695 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nkx6-1 NK6 homeobox 1 increases expression EXP Phlorhizin results in increased expression of NKX6-1 mRNA CTD PMID:16123366 NCBI chr 5:101,807,050...101,812,577
Ensembl chr 5:101,806,005...101,812,862 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
decreases expression		 ISO Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
Phlorhizin results in decreased expression of NOS3 mRNA		 CTD PMID:20021702 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nras neuroblastoma ras oncogene decreases expression EXP Phlorhizin results in decreased expression of NRAS mRNA CTD PMID:22538082 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230 		JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) decreases expression EXP Phlorhizin results in decreased expression of OGDH mRNA CTD PMID:22538082 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642 		JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 increases expression EXP Phlorhizin results in increased expression of PARK7 mRNA CTD PMID:22538082 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894 		JBrowse link
G Pcca propionyl-Coenzyme A carboxylase, alpha polypeptide decreases expression EXP Phlorhizin results in decreased expression of PCCA mRNA CTD PMID:22538082 NCBI chr14:122,721,822...123,127,372
Ensembl chr14:122,771,736...123,128,512 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic decreases expression EXP Phlorhizin results in decreased expression of PCK1 mRNA CTD PMID:22538082 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pcx pyruvate carboxylase increases expression
decreases expression		 EXP Phlorhizin results in increased expression of PCX mRNA
Phlorhizin results in decreased expression of PC mRNA		 CTD PMID:16123366 PMID:22538082 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase increases expression
decreases expression		 EXP Phlorhizin results in increased expression of PECR mRNA
Phlorhizin results in decreased expression of PECR mRNA		 CTD PMID:22538082 NCBI chr 1:72,298,331...72,323,480
Ensembl chr 1:72,298,326...72,323,473 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha decreases expression EXP Phlorhizin results in decreased expression of PIK3C2A mRNA CTD PMID:22538082 NCBI chr 7:115,936,500...116,042,693
Ensembl chr 7:115,936,500...116,042,684 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 decreases expression EXP Phlorhizin results in decreased expression of PIK3C3 mRNA CTD PMID:22538082 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179 		JBrowse link
G Pink1 PTEN induced putative kinase 1 increases expression EXP Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP Phlorhizin results in increased expression of PRDX1 mRNA CTD PMID:22538082 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression EXP Phlorhizin results in decreased expression of PRDX5 mRNA CTD PMID:22538082 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474 		JBrowse link
G Prkch protein kinase C, eta increases expression EXP Phlorhizin results in increased expression of PRKCH mRNA CTD PMID:22538082 NCBI chr12:73,631,570...73,824,959
Ensembl chr12:73,631,570...73,824,959 		JBrowse link
G Prkci protein kinase C, iota decreases expression EXP Phlorhizin results in decreased expression of PRKCI mRNA CTD PMID:22538082 NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108 		JBrowse link
G Prkd3 protein kinase D3 decreases expression EXP Phlorhizin results in decreased expression of PRKD3 mRNA CTD PMID:22538082 NCBI chr17:79,256,834...79,328,245
Ensembl chr17:79,256,834...79,328,245 		JBrowse link
G Psma4 proteasome subunit alpha 4 decreases expression EXP Phlorhizin results in decreased expression of PSMA4 mRNA CTD PMID:22538082 NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314 		JBrowse link
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 increases expression EXP Phlorhizin results in increased expression of PSMB1 mRNA CTD PMID:22538082 NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013 		JBrowse link
G Psmb2 proteasome (prosome, macropain) subunit, beta type 2 decreases expression EXP Phlorhizin results in decreased expression of PSMB2 mRNA CTD PMID:22538082 NCBI chr 4:126,571,460...126,603,503
Ensembl chr 4:126,571,423...126,603,507 		JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 decreases expression EXP Phlorhizin results in decreased expression of PSMC1 mRNA CTD PMID:22538082 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664 		JBrowse link
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 increases expression
decreases expression		 EXP Phlorhizin results in increased expression of PSMC4 mRNA
Phlorhizin results in decreased expression of PSMC4 mRNA		 CTD PMID:22538082 NCBI chr 7:27,741,127...27,749,517
Ensembl chr 7:27,741,132...27,749,526 		JBrowse link
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 decreases expression EXP Phlorhizin results in decreased expression of PSMC6 mRNA CTD PMID:22538082 NCBI chr14:45,567,285...45,587,150
Ensembl chr14:45,567,245...45,587,162 		JBrowse link
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 decreases expression EXP Phlorhizin results in decreased expression of PSMD10 mRNA CTD PMID:22538082 NCBI chr  X:139,849,174...139,857,460
Ensembl chr  X:139,849,178...139,857,477 		JBrowse link
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 decreases expression EXP Phlorhizin results in decreased expression of PSMD12 mRNA CTD PMID:22538082 NCBI chr11:107,370,354...107,388,862
Ensembl chr11:107,370,310...107,395,188 		JBrowse link
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 decreases expression EXP Phlorhizin results in decreased expression of PSMD14 mRNA CTD PMID:22538082 NCBI chr 2:61,542,038...61,630,720
Ensembl chr 2:61,542,038...61,630,720 		JBrowse link
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 decreases expression EXP Phlorhizin results in decreased expression of PSMD4 mRNA CTD PMID:22538082 NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925 		JBrowse link
G Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 increases expression EXP Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 NCBI chr14:8,348,818...8,357,578
Ensembl chr14:8,348,779...8,357,589 		JBrowse link
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 decreases expression EXP Phlorhizin results in decreased expression of PSMD7 mRNA CTD PMID:22538082 NCBI chr 8:108,307,012...108,315,114
Ensembl chr 8:108,307,013...108,315,096 		JBrowse link
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 decreases expression EXP Phlorhizin results in decreased expression of PSMD9 mRNA CTD PMID:22538082 NCBI chr 5:123,366,253...123,388,189
Ensembl chr 5:123,307,476...123,388,194 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 decreases expression EXP Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rdh14 retinol dehydrogenase 14 (all-trans and 9-cis) increases expression EXP Phlorhizin results in increased expression of RDH14 mRNA CTD PMID:22538082 NCBI chr12:10,440,752...10,445,562
Ensembl chr12:10,440,772...10,445,562 		JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) decreases expression EXP Phlorhizin results in decreased expression of S100A6 mRNA CTD PMID:16123366 NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488 		JBrowse link
G Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) decreases expression EXP Phlorhizin results in decreased expression of SDHA mRNA CTD PMID:22538082 NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399 		JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) increases expression EXP Phlorhizin results in increased expression of SDHB mRNA CTD PMID:22538082 NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504 		JBrowse link
G Sds serine dehydratase decreases expression EXP Phlorhizin results in decreased expression of SDS mRNA CTD PMID:22538082 NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 increases expression EXP Phlorhizin results in increased expression of SLC2A2 mRNA CTD PMID:16123366 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc35a2 solute carrier family 35 (UDP-galactose transporter), member A2 increases expression EXP Phlorhizin results in increased expression of SLC35A2 mRNA CTD PMID:22538082 NCBI chr  X:7,750,189...7,760,699
Ensembl chr  X:7,750,267...7,760,731 		JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions
affects binding
decreases activity		 ISO
EXP		 Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside]; Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
SLC5A1 protein binds to Phlorhizin
Phlorhizin results in decreased activity of SLC5A1 protein
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside		 CTD PMID:12663055 PMID:12927799 PMID:16300400 PMID:17288452 PMID:17983207 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214 		JBrowse link
G Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 decreases activity ISO Phlorhizin results in decreased activity of SLC5A2 protein CTD PMID:21128592 NCBI chr 7:127,864,855...127,871,602
Ensembl chr 7:127,864,829...127,871,602 		JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression EXP Phlorhizin results in increased expression of SOD1 mRNA CTD PMID:22538082 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression EXP Phlorhizin results in decreased expression of SOD2 mRNA CTD PMID:22538082 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression EXP Phlorhizin results in decreased expression of STIP1 mRNA CTD PMID:22538082 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335 		JBrowse link
G Sucla2 succinate-Coenzyme A ligase, ADP-forming, beta subunit decreases expression EXP Phlorhizin results in decreased expression of SUCLA2 mRNA CTD PMID:22538082 NCBI chr14:73,790,226...73,833,584
Ensembl chr14:73,762,759...73,833,582 		JBrowse link
G Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit decreases expression EXP Phlorhizin results in decreased expression of SUCLG2 mRNA CTD PMID:22538082 NCBI chr 6:95,449,992...95,695,799
Ensembl chr 6:95,449,990...95,695,781 		JBrowse link
G Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) decreases expression EXP Phlorhizin results in decreased expression of SUGT1 mRNA CTD PMID:22538082 NCBI chr14:79,825,100...79,868,237
Ensembl chr14:79,825,131...79,872,636 		JBrowse link
G Txn1 thioredoxin 1 decreases expression
increases expression		 EXP Phlorhizin results in decreased expression of TXN mRNA
Phlorhizin results in increased expression of TXN mRNA		 CTD PMID:22538082 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Txn2 thioredoxin 2 increases expression EXP Phlorhizin results in increased expression of TXN2 mRNA CTD PMID:22538082 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206 		JBrowse link
G Ubb ubiquitin B increases expression EXP Phlorhizin results in increased expression of UBB mRNA CTD PMID:22538082 NCBI chr11:62,442,329...62,444,037
Ensembl chr11:62,441,997...62,444,039 		JBrowse link
G Ubc ubiquitin C decreases expression EXP Phlorhizin results in decreased expression of UBC mRNA CTD PMID:22538082 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B decreases expression EXP Phlorhizin results in decreased expression of UBE2B mRNA CTD PMID:22538082 NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589 		JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression EXP Phlorhizin results in decreased expression of UBE2F mRNA CTD PMID:22538082 NCBI chr 1:91,177,412...91,214,243
Ensembl chr 1:91,178,026...91,218,059 		JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H decreases expression EXP Phlorhizin results in decreased expression of UBE2H mRNA CTD PMID:22538082 NCBI chr 6:30,211,288...30,304,538
Ensembl chr 6:30,211,288...30,304,538 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I decreases expression EXP Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856 		JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 decreases expression EXP Phlorhizin results in decreased expression of UBE2L3 mRNA CTD PMID:22538082 NCBI chr16:16,969,879...17,019,363
Ensembl chr16:16,969,877...17,020,513 		JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M increases expression EXP Phlorhizin results in increased expression of UBE2M mRNA CTD PMID:22538082 NCBI chr 7:12,769,047...12,772,202
Ensembl chr 7:12,769,047...12,772,202 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression EXP Phlorhizin results in decreased expression of UBE2N mRNA CTD PMID:22538082 NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519 		JBrowse link
G Ube2q1 ubiquitin-conjugating enzyme E2Q family member 1 increases expression EXP Phlorhizin results in increased expression of UBE2Q1 mRNA CTD PMID:22538082 NCBI chr 3:89,680,905...89,691,304
Ensembl chr 3:89,680,923...89,691,307 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 decreases expression EXP Phlorhizin results in decreased expression of UBE2R2 mRNA CTD PMID:22538082 NCBI chr 4:41,136,021...41,193,370
Ensembl chr 4:41,135,743...41,193,380 		JBrowse link
G Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 decreases expression EXP Phlorhizin results in decreased expression of UBE2V2 mRNA CTD PMID:22538082 NCBI chr16:15,368,850...15,412,382
Ensembl chr16:15,369,941...15,413,637 		JBrowse link
G Ube4a ubiquitination factor E4A increases expression EXP Phlorhizin results in increased expression of UBE4A mRNA CTD PMID:22538082 NCBI chr 9:44,834,425...44,877,021
Ensembl chr 9:44,834,425...44,876,898 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression EXP Phlorhizin results in increased expression of UBR2 mRNA CTD PMID:22538082 NCBI chr17:47,239,217...47,321,812
Ensembl chr17:47,239,221...47,321,482 		JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) decreases expression EXP Phlorhizin results in decreased expression of UCHL3 mRNA CTD PMID:22538082 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561 		JBrowse link
G Uchl5 ubiquitin carboxyl-terminal esterase L5 decreases expression EXP Phlorhizin results in decreased expression of UCHL5 mRNA CTD PMID:22538082 NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases activity ISO Phlorhizin results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 decreases activity ISO Phlorhizin results in decreased activity of UGT1A10 protein CTD PMID:35868516 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO Phlorhizin results in decreased activity of UGT1A3 protein CTD PMID:35868516 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases activity ISO Phlorhizin results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO Phlorhizin results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 decreases activity ISO Phlorhizin results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression EXP Phlorhizin results in decreased expression of UQCRC2 mRNA CTD PMID:22538082 NCBI chr 7:120,234,412...120,258,746
Ensembl chr 7:120,234,399...120,258,747 		JBrowse link
G Usp1 ubiquitin specific peptidase 1 increases expression EXP Phlorhizin results in increased expression of USP1 mRNA CTD PMID:22538082 NCBI chr 4:98,812,047...98,823,780
Ensembl chr 4:98,812,047...98,823,780 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 decreases expression EXP Phlorhizin results in decreased expression of USP14 mRNA CTD PMID:22538082 NCBI chr18:9,993,615...10,030,149
Ensembl chr18:9,993,066...10,045,119 		JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression EXP Phlorhizin results in increased expression of USP19 mRNA CTD PMID:22538082 NCBI chr 9:108,367,806...108,379,536
Ensembl chr 9:108,367,801...108,379,536 		JBrowse link
G Usp24 ubiquitin specific peptidase 24 decreases expression EXP Phlorhizin results in decreased expression of USP24 mRNA CTD PMID:22538082 NCBI chr 4:106,173,179...106,303,798
Ensembl chr 4:106,173,417...106,298,519 		JBrowse link
G Usp33 ubiquitin specific peptidase 33 decreases expression EXP Phlorhizin results in decreased expression of USP33 mRNA CTD PMID:22538082 NCBI chr 3:152,051,797...152,099,254
Ensembl chr 3:152,052,115...152,099,254 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) increases expression EXP Phlorhizin results in increased expression of USP4 mRNA CTD PMID:22538082 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744 		JBrowse link
G Usp45 ubiquitin specific petidase 45 decreases expression EXP Phlorhizin results in decreased expression of USP45 mRNA CTD PMID:22538082 NCBI chr 4:21,767,161...21,837,872
Ensembl chr 4:21,767,156...21,837,872 		JBrowse link
G Usp46 ubiquitin specific peptidase 46 decreases expression EXP Phlorhizin results in decreased expression of USP46 mRNA CTD PMID:22538082 NCBI chr 5:74,159,387...74,229,070
Ensembl chr 5:74,159,114...74,229,092 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 decreases expression EXP Phlorhizin results in decreased expression of USP7 mRNA CTD PMID:22538082 NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X chromosome decreases expression EXP Phlorhizin results in decreased expression of USP9X mRNA CTD PMID:22538082 NCBI chr  X:12,937,221...13,039,567
Ensembl chr  X:12,937,737...13,039,567 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA CTD PMID:32408695 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression EXP Phlorhizin results in decreased expression of XIAP mRNA CTD PMID:22538082 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533 		JBrowse link
trilobatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein] CTD PMID:30104959 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:30104959 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Cat catalase multiple interactions EXP NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein] CTD PMID:32663520 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] CTD PMID:30104959 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] CTD PMID:30104959 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] CTD PMID:30104959 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP
ISO		 trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] CTD PMID:30104959 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:25053100 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:25053100 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA] CTD PMID:30104959 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607 		JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA] CTD PMID:30104959 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872 		JBrowse link
G mt-Cytb cytochrome b, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA] CTD PMID:30104959 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288 		JBrowse link
G mt-Nd2 NADH dehydrogenase 2, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA] CTD PMID:30104959 NCBI chr MT:3,914...4,951
Ensembl chr MT:3,914...4,951 		JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA] CTD PMID:30104959 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO
EXP		 trilobatin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]
NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:25053100 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP
ISO		 trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:25053100 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] CTD PMID:30104959 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein] CTD PMID:30104959 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:25053100 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein] CTD PMID:30104959 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    role 22167
      application 21752
        pharmaceutical 21167
          drug 21167
            antineoplastic agent 18880
              phloretin 315
                3-hydroxyphloretin 2'-O-xylosylglucoside 0
                asebogenin 0
                glycyphyllin 0
                phlorizin 249
                trilobatin 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      carbon group element atom 21909
                        carbon atom 21835
                          organic molecular entity 21835
                            heteroorganic entity 21490
                              organochalcogen compound 20980
                                organooxygen compound 20821
                                  carbonyl compound 20190
                                    ketone 17957
                                      aromatic ketone 12602
                                        dihydrochalcones 753
                                          dihydrochalcone 315
                                            phloretin 315
                                              3-hydroxyphloretin 2'-O-xylosylglucoside 0
                                              asebogenin 0
                                              glycyphyllin 0
                                              phlorizin 249
                                              trilobatin 25
paths to the root