Suclg2 (succinate-Coenzyme A ligase, GDP-forming, beta subunit) - Rat Genome Database

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Gene: Suclg2 (succinate-Coenzyme A ligase, GDP-forming, beta subunit) Mus musculus
Analyze
Symbol: Suclg2
Name: succinate-Coenzyme A ligase, GDP-forming, beta subunit
RGD ID: 1312780
MGI Page MGI
Description: Predicted to enable GDP binding activity; succinate-CoA ligase (GDP-forming) activity; and succinate-semialdehyde dehydrogenase (NAD+) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AF171077; AW556404; D6Wsu120; D6Wsu120e; G-SCS; GTP-specific succinyl-CoA synthetase beta subunit; GTP-specific succinyl-CoA synthetase subunit beta; GTPSCS; MGC91183; SCS-betaG; succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; succinyl-CoA synthetase beta-G chain
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm15163   Gm19102  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39695,449,992 - 95,695,799 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl695,449,990 - 95,695,781 (-)EnsemblGRCm39 Ensembl
GRCm38695,473,009 - 95,718,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl695,473,009 - 95,718,800 (-)EnsemblGRCm38mm10GRCm38
MGSCv37695,424,128 - 95,668,831 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36695,439,609 - 95,684,251 (-)NCBIMGSCv36mm8
Celera697,363,804 - 97,602,843 (-)NCBICelera
Cytogenetic Map6D2NCBI
cM Map644.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Suclg2Mousemitochondrial DNA depletion syndrome 9  ISOSUCLG2 (Homo sapiens)8554872ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 9ClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Suclg2MouseAnimal Disease Models  ISOSUCLG2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772
Suclg2Mouseendometriosis  ISOSUCLG2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23284138
Suclg2Mouselung adenocarcinoma  ISOSUCLG2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772
Suclg2Mousemethylmalonic acidemia  ISOSUCLG2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16823967
Suclg2Mouseobesity  ISOSUCLG2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20882379

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Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Suclg2Mouse(1->4)-beta-D-glucan multiple interactionsEXP 6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SUCLG2 mRNACTDPMID:36331819
Suclg2Mouse(R)-adrenaline increases expressionISOSuclg2 (Rattus norvegicus)6480464Epinephrine results in increased expression of SUCLG2 proteinCTDPMID:19464573
Suclg2Mouse1,2-dimethylhydrazine multiple interactionsEXP 6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SUCLG2 mRNACTDPMID:22206623
Suclg2Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of SUCLG2 mRNACTDPMID:22206623
Suclg2Mouse17beta-estradiol multiple interactionsISOSuclg2 (Rattus norvegicus)6480464[bisphenol A co-treated with Estradiol] results in decreased expression of SUCLG2 mRNACTDPMID:26496021
Suclg2Mouse17beta-estradiol decreases expressionISOSuclg2 (Rattus norvegicus)6480464Estradiol results in decreased expression of SUCLG2 mRNACTDPMID:32145629
Suclg2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of SUCLG2 mRNACTDPMID:19465110
Suclg2Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of SUCLG2 mRNACTDPMID:21570461
Suclg2Mouse2,4-dinitrotoluene affects expressionISOSuclg2 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of SUCLG2 mRNACTDPMID:21346803
Suclg2Mouse2,6-dimethoxyphenol multiple interactionsISOSUCLG2 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of SUCLG2 proteinCTDPMID:38598786
Suclg2Mouse2,6-dinitrotoluene affects expressionISOSuclg2 (Rattus norvegicus)64804642 and 6-dinitrotoluene affects the expression of SUCLG2 mRNACTDPMID:21346803
Suclg2Mouse4,4'-sulfonyldiphenol increases expressionISOSUCLG2 (Homo sapiens)6480464bisphenol S results in increased expression of SUCLG2 proteinCTDPMID:34186270
Suclg2Mouse4-hydroxyphenyl retinamide increases expressionEXP 6480464Fenretinide results in increased expression of SUCLG2 mRNACTDPMID:28973697
Suclg2Mouse5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid decreases expressionISOSUCLG2 (Homo sapiens)6480464acipimox results in decreased expression of SUCLG2 mRNACTDPMID:25352640
Suclg2Mouse7H-xanthine multiple interactionsISOSuclg2 (Rattus norvegicus)6480464[Xanthine co-treated with XDH protein] results in decreased expression of SUCLG2 proteinCTDPMID:19464573
Suclg2Mouse9H-xanthine multiple interactionsISOSuclg2 (Rattus norvegicus)6480464[Xanthine co-treated with XDH protein] results in decreased expression of SUCLG2 proteinCTDPMID:19464573
Suclg2Mouseacetamide decreases expressionISOSuclg2 (Rattus norvegicus)6480464acetamide results in decreased expression of SUCLG2 mRNACTDPMID:31881176
Suclg2Mouseacrolein multiple interactionsISOSUCLG2 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SUCLG2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SUCLG2 mRNACTDPMID:32699268
Suclg2Mouseacrylamide decreases expressionISOSUCLG2 (Homo sapiens)6480464Acrylamide results in decreased expression of SUCLG2 mRNACTDPMID:32763439
Suclg2Mouseaflatoxin B1 affects expressionISOSUCLG2 (Homo sapiens)6480464Aflatoxin B1 affects the expression of SUCLG2 proteinCTDPMID:20106945

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Biological Process
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Suclg2Mousemitochondrion is_active_inIBAPANTHER:PTN000212530 more ...2290270 GO_CentralGO_REF:0000033
Suclg2Mousemitochondrion located_inISOUniProtKB:Q96I992290270 GO_CentralGO_REF:0000119
Suclg2Mousemitochondrion located_inHDA 2290270 PMID:14651853 and PMID:18614015MGIPMID:14651853 and PMID:18614015
Suclg2Mouseplasma membrane located_inISOUniProtKB:Q96I992290270 GO_CentralGO_REF:0000119
Suclg2Mouseplasma membrane located_inIEAUniProtKB:Q96I99 and ensembl:ENSP000003074322290270 EnsemblGO_REF:0000107
Suclg2Mouseprotein-containing complex part_ofISOSuclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Suclg2Mouseprotein-containing complex  ISOSuclg2 (Rattus norvegicus)9068941Nme4 and Suclg1RGDPMID:11831846 and REF_RGD_ID:2299079
Suclg2Mousesuccinate-CoA ligase complex part_ofIBAPANTHER:PTN000212531 more ...2290270 GO_CentralGO_REF:0000033
Suclg2Mousesuccinate-CoA ligase complex (GDP-forming) part_ofISOSuclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Suclg2Mousesuccinate-CoA ligase complex (GDP-forming) part_ofIEAUniProtKB:A0A8I6AIH6 more ...2290270 EnsemblGO_REF:0000107
Suclg2Mousesuccinate-CoA ligase complex (GDP-forming) part_ofIGIMGI:13067752290270 PMID:27496549MGIPMID:27496549
Suclg2Mousesuccinate-CoA ligase complex (GDP-forming)  ISOSuclg2 (Rattus norvegicus)9068941 RGDPMID:7430155 and REF_RGD_ID:2306879
Suclg2Mousesuccinate-CoA ligase complex (GDP-forming) part_ofISOUniProtKB:Q96I992290270 GO_CentralGO_REF:0000119
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Molecular Function
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Object Symbol
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Reference
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Source
Original Reference(s)
Suclg2MouseATP binding enablesIEAInterPro:IPR011761 and InterPro:IPR0138152290270 InterProGO_REF:0000002
Suclg2MouseGDP binding enablesISOSuclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Suclg2MouseGDP binding enablesIEAUniProtKB:A0A8I6AIH6 and ensembl:ENSRNOP000000926042290270 EnsemblGO_REF:0000107
Suclg2MouseGDP binding  ISOSuclg2 (Rattus norvegicus)9068941 RGDPMID:7430155 and REF_RGD_ID:2306879
Suclg2MouseGTP binding enablesIEAUniRule:UR0004059122290270 UniProtGO_REF:0000104
Suclg2Mousemagnesium ion binding enablesIEAUniRule:UR0004059122290270 UniProtGO_REF:0000104
Suclg2Mouseprotein binding enablesISOUniProtKB:P535979068941 PMID:28514442 more ...IntActPMID:28514442 more ...
Suclg2Mouseprotein binding enablesISOUniProtKB:O190699068941 PMID:10873456IntActPMID:10873456
Suclg2Mouseprotein binding enablesISOUniProtKB:Q8IWL39068941 PMID:24606901 and PMID:28380382IntActPMID:24606901 and PMID:28380382
Suclg2Mouseprotein-containing complex binding  ISOSuclg2 (Rattus norvegicus)9068941heterodimerizationRGDPMID:7430155 and REF_RGD_ID:2306879
Suclg2Mouseprotein-containing complex binding enablesIEAUniProtKB:A0A8I6AIH6 and ensembl:ENSRNOP000000926042290270 EnsemblGO_REF:0000107
Suclg2Mouseprotein-containing complex binding enablesISOSuclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Suclg2Mousesuccinate-CoA ligase (ADP-forming) activity enablesIEAUniRule:UR0004059122290270 UniProtGO_REF:0000104
Suclg2Mousesuccinate-CoA ligase (ADP-forming) activity NOT|enablesIBAPANTHER:PTN000929335 and PANTHER:PTN0002125312290270 GO_CentralGO_REF:0000033
Suclg2Mousesuccinate-CoA ligase (GDP-forming) activity enablesISOSuclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Suclg2Mousesuccinate-CoA ligase (GDP-forming) activity enablesIBAPANTHER:PTN000929335 and Suclg2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000033
Suclg2Mousesuccinate-CoA ligase (GDP-forming) activity enablesIEAEC:6.2.1.42290270 UniProtGO_REF:0000003
Suclg2Mousesuccinate-CoA ligase (GDP-forming) activity enablesIEARHEA:221202290270 RHEAGO_REF:0000116
Suclg2Mousesuccinate-CoA ligase (GDP-forming) activity  ISOSuclg2 (Rattus norvegicus)9068941 RGDPMID:17403370 more ...
Suclg2Mousesuccinate-semialdehyde dehydrogenase (NAD+) activity enablesISAEMBL:AF008588 and EMBL:AF0353942290270 PMID:9765291MGIPMID:9765291
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RGD Manual Annotations


  
Object Symbol
Species
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Evidence
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Reference
Notes
Source
Original Reference(s)
Suclg2Mousecitric acid cycle pathway   ISOSuclg2 (Rattus norvegicus)2306915 RGD 

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Suclg2Mousecitric acid cycle pathway   IEA 6907045 KEGGmmu:00020
Suclg2Mousepropanoate metabolic pathway  IEA 6907045 KEGGmmu:00640

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Reference Title
Reference Citation
1. Mitochondrial GTP regulates glucose-stimulated insulin secretion. Kibbey RG, etal., Cell Metab. 2007 Apr;5(4):253-64.
2. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:9765291   PMID:10349636   PMID:10512203   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11812828   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199   PMID:15840001   PMID:16141072   PMID:16141073   PMID:17626619   PMID:18614015   PMID:18799693   PMID:21267068   PMID:21873635  
PMID:22496890   PMID:25027320   PMID:26697723   PMID:27215380   PMID:27496549   PMID:27746211   PMID:28130547   PMID:28245920   PMID:28378742   PMID:29199018   PMID:29222160   PMID:30457570  
PMID:30498063   PMID:30951662   PMID:31097699   PMID:31138677   PMID:32325033   PMID:33601422   PMID:34321999   PMID:35237793   PMID:36114006   PMID:37839992   PMID:38355793   PMID:38588611  



Suclg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39695,449,992 - 95,695,799 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl695,449,990 - 95,695,781 (-)EnsemblGRCm39 Ensembl
GRCm38695,473,009 - 95,718,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl695,473,009 - 95,718,800 (-)EnsemblGRCm38mm10GRCm38
MGSCv37695,424,128 - 95,668,831 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36695,439,609 - 95,684,251 (-)NCBIMGSCv36mm8
Celera697,363,804 - 97,602,843 (-)NCBICelera
Cytogenetic Map6D2NCBI
cM Map644.63NCBI
SUCLG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38367,360,460 - 67,654,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl367,360,460 - 67,654,612 (-)EnsemblGRCh38hg38GRCh38
GRCh37367,410,884 - 67,705,036 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36367,507,833 - 67,787,728 (-)NCBINCBI36Build 36hg18NCBI36
Build 34367,507,835 - 67,787,698NCBI
Celera367,353,993 - 67,645,444 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef367,427,311 - 67,718,351 (-)NCBIHuRef
CHM1_1367,362,353 - 67,656,266 (-)NCBICHM1_1
T2T-CHM13v2.0367,405,452 - 67,699,926 (-)NCBIT2T-CHM13v2.0
Suclg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84129,623,833 - 129,893,937 (-)NCBIGRCr8
mRatBN7.24128,067,031 - 128,337,146 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4128,067,033 - 128,337,170 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4133,537,045 - 133,796,153 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04129,311,467 - 129,570,570 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04127,936,011 - 128,195,129 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04127,552,100 - 127,824,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4127,552,101 - 127,824,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04192,061,200 - 192,333,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44129,995,856 - 130,276,182 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14130,240,697 - 130,521,016 (-)NCBI
Celera4116,961,947 - 117,231,527 (-)NCBICelera
Cytogenetic Map4q34NCBI
Suclg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542120,089,237 - 20,350,843 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542120,089,471 - 20,350,334 (+)NCBIChiLan1.0ChiLan1.0
SUCLG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2267,297,278 - 67,583,115 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1367,302,066 - 67,587,910 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0367,277,348 - 67,563,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1368,646,711 - 68,931,961 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl368,647,738 - 68,931,891 (-)Ensemblpanpan1.1panPan2
SUCLG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12023,915,149 - 24,167,740 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2023,895,802 - 24,182,869 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2023,886,104 - 24,138,714 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02023,942,402 - 24,194,878 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2023,923,303 - 24,210,054 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12023,639,932 - 23,892,783 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02023,985,458 - 24,238,734 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02024,045,666 - 24,298,090 (+)NCBIUU_Cfam_GSD_1.0
Suclg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404942243,107 - 378,528 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936603243,113 - 378,528 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936603243,113 - 378,526 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUCLG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1348,823,733 - 49,090,468 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11348,650,851 - 49,090,521 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21353,872,520 - 54,030,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUCLG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12228,382,612 - 28,677,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2228,381,787 - 28,677,742 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041138,141,609 - 138,419,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suclg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247731,818,374 - 2,087,331 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247731,816,924 - 2,087,384 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Suclg2
12639 total Variants

Predicted Target Of
Summary Value
Count of predictions:333
Count of miRNA genes:260
Interacting mature miRNAs:292
Transcripts:ENSMUST00000079847
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
11532719Sluc45_msusceptibility to lung cancer 45 (mouse)69258428798235894Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse

1 to 10 of 40 rows
AW556404  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38695,473,064 - 95,473,163UniSTSGRCm38
MGSCv37695,423,058 - 95,423,157UniSTSGRCm37
Celera697,362,734 - 97,362,833UniSTS
Cytogenetic Map6D3UniSTS
cM Map641.0UniSTS
Whitehead/MRC_RH6980.23UniSTS
RH124559  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38695,474,264 - 95,474,491UniSTSGRCm38
GRCm38X157,015,446 - 157,015,673UniSTSGRCm38
MGSCv37695,424,258 - 95,424,485UniSTSGRCm37
MGSCv37X153,449,989 - 153,450,216UniSTSGRCm37
CeleraX140,275,602 - 140,275,829UniSTS
Celera697,363,934 - 97,364,161UniSTS
Cytogenetic Map6D3UniSTS
Cytogenetic MapXF4UniSTS
cM Map641.0UniSTS
Suclg2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,015,622 - 157,016,583UniSTSGRCm38
MGSCv37X153,450,165 - 153,451,126UniSTSGRCm37
CeleraX140,275,778 - 140,276,739UniSTS
Cytogenetic MapXF4UniSTS
Cytogenetic Map6D3UniSTS
cM Map641.0UniSTS
UniSTS:235506  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38695,561,725 - 95,562,065UniSTSGRCm38
MGSCv37695,511,719 - 95,512,059UniSTSGRCm37
Celera697,452,495 - 97,452,835UniSTS
Cytogenetic Map6D3UniSTS
cM Map641.0UniSTS
D6Wsu120e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38695,474,239 - 95,474,488UniSTSGRCm38
GRCm38X157,015,421 - 157,015,670UniSTSGRCm38
MGSCv37X153,449,964 - 153,450,213UniSTSGRCm37
MGSCv37695,424,233 - 95,424,482UniSTSGRCm37
CeleraX140,275,577 - 140,275,826UniSTS
Celera697,363,909 - 97,364,158UniSTS
Cytogenetic Map6D3UniSTS
Cytogenetic MapXF4UniSTS
cM Map641.0UniSTS






1 to 30 of 33 rows
RefSeq Transcripts NM_001326558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC125225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC135018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF058956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF171077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI482427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 33 rows

Ensembl Acc Id: ENSMUST00000079847   ⟹   ENSMUSP00000078774
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl695,451,123 - 95,669,863 (-)Ensembl
GRCm38.p6 Ensembl695,474,142 - 95,692,882 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl695,543,466 - 95,620,990 (-)Ensembl
GRCm38.p6 Ensembl695,566,485 - 95,644,009 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203109
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl695,631,732 - 95,695,781 (-)Ensembl
GRCm38.p6 Ensembl695,654,751 - 95,718,800 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204224   ⟹   ENSMUSP00000144827
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl695,449,990 - 95,695,781 (-)Ensembl
GRCm38.p6 Ensembl695,473,009 - 95,718,800 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204567   ⟹   ENSMUSP00000145471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl695,571,664 - 95,634,449 (-)Ensembl
GRCm38.p6 Ensembl695,594,683 - 95,657,468 (-)Ensembl
RefSeq Acc Id: NM_001326558   ⟹   NP_001313487
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,669,693 (-)NCBI
GRCm38695,473,009 - 95,692,882 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001410411   ⟹   NP_001397340
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,695,799 (-)NCBI
RefSeq Acc Id: NM_011507   ⟹   NP_035637
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,695,799 (-)NCBI
GRCm38695,473,009 - 95,718,846 (-)NCBI
MGSCv37695,424,128 - 95,668,831 (-)RGD
Celera697,362,679 - 97,602,851 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_177067
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,695,799 (-)NCBI
RefSeq Acc Id: NR_177068
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,695,799 (-)NCBI
RefSeq Acc Id: NR_177069
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39695,449,992 - 95,695,799 (-)NCBI
RefSeq Acc Id: NP_035637   ⟸   NM_011507
- Peptide Label: isoform 1 precursor
- UniProtKB: Q80VV1 (UniProtKB/Swiss-Prot),   Q7TMY3 (UniProtKB/Swiss-Prot),   Q66JT3 (UniProtKB/Swiss-Prot),   Q3TK63 (UniProtKB/Swiss-Prot),   Q3TJQ5 (UniProtKB/Swiss-Prot),   Q3T9B8 (UniProtKB/Swiss-Prot),   Q8K2K9 (UniProtKB/Swiss-Prot),   Q9Z2I8 (UniProtKB/Swiss-Prot),   C6EQH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001313487   ⟸   NM_001326558
- Peptide Label: isoform 2
- UniProtKB: C6EQH3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144827   ⟸   ENSMUST00000204224
Ensembl Acc Id: ENSMUSP00000078774   ⟸   ENSMUST00000079847
Ensembl Acc Id: ENSMUSP00000145471   ⟸   ENSMUST00000204567
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2I8-F1-model_v2 AlphaFold Q9Z2I8 1-433 view protein structure

RGD ID:6840037
Promoter ID:MM_KWN:46988
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver,   Lung,   MEF_B6
Transcripts:NM_011507,   UC009DAC.1,   UC009DAD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36695,668,326 - 95,668,826 (-)MPROMDB
RGD ID:6890504
Promoter ID:EPDNEW_M8703
Type:multiple initiation site
Name:Suclg2_1
Description:Mus musculus succinate-Coenzyme A ligase, GDP-forming, beta subunit, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38695,718,789 - 95,718,849EPDNEW


1 to 40 of 46 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000061838 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000079847 ENTREZGENE
  ENSMUST00000079847.8 UniProtKB/Swiss-Prot
  ENSMUST00000204224 ENTREZGENE
  ENSMUST00000204224.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1490.20 UniProtKB/Swiss-Prot
  3.40.50.261 UniProtKB/Swiss-Prot
  ATP-grasp fold, B domain UniProtKB/Swiss-Prot
InterPro ATP-grasp UniProtKB/Swiss-Prot
  ATP-grasp_succ-CoA_synth-type UniProtKB/Swiss-Prot
  ATP_grasp_subdomain_1 UniProtKB/Swiss-Prot
  CoA_ligase UniProtKB/Swiss-Prot
  Succ-CoA_synthase_bsu_CS UniProtKB/Swiss-Prot
  Succ_CoA_betaG_euk UniProtKB/Swiss-Prot
  Succ_CoA_synthase_bsu UniProtKB/Swiss-Prot
  Succinyl-CoA_synth-like UniProtKB/Swiss-Prot
KEGG Report mmu:20917 UniProtKB/Swiss-Prot
MGD MGI:1306824 ENTREZGENE
NCBI Gene 20917 ENTREZGENE
PANTHER PTHR11815 UniProtKB/Swiss-Prot
  SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam ATP-grasp_2 UniProtKB/Swiss-Prot
  Ligase_CoA UniProtKB/Swiss-Prot
PhenoGen Suclg2 PhenoGen
PIRSF SucCS_beta UniProtKB/Swiss-Prot
PROSITE ATP_GRASP UniProtKB/Swiss-Prot
  SUCCINYL_COA_LIG_3 UniProtKB/Swiss-Prot
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot
  SSF52210 UniProtKB/Swiss-Prot
UniProt A0A0N4SWD1_MOUSE UniProtKB/TrEMBL
  C6EQH3 ENTREZGENE, UniProtKB/TrEMBL
  Q3T9B8 ENTREZGENE
  Q3TJQ5 ENTREZGENE
  Q3TK63 ENTREZGENE
  Q66JT3 ENTREZGENE
  Q7TMY3 ENTREZGENE
  Q80VV1 ENTREZGENE
  Q8K2K9 ENTREZGENE
  Q9Z2I8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3T9B8 UniProtKB/Swiss-Prot
1 to 40 of 46 rows