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Gene: Actb (actin, beta) Mus musculus
Symbol: Actb
Name: actin, beta
Description: Predicted to have several functions, including Tat protein binding activity; enzyme binding activity; and identical protein binding activity. Involved in negative regulation of protein binding activity and synaptic vesicle endocytosis. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; calyx of Held; and cortical cytoskeleton. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome. Is expressed in several structures, including early conceptus; genitourinary system; musculature; spleen; and tooth. Orthologous to human ACTB (actin beta).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A-X actin-like protein; actin, beta, cytoplasmic; actin, cytoplasmic 1; Actx; beta-actin; E430023M04Rik; melanoma X-actin
Homo sapiens (human) : ACTB (actin beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Actb (actin, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actb (actin beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTB (actin beta)
Canis lupus familiaris (dog) : ACTB (actin beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actb (actin beta)
Sus scrofa (pig) : ACTB (actin beta)
Chlorocebus sabaeus (green monkey) : ACTB (actin beta)
Heterocephalus glaber (naked mole-rat) : Actb (actin beta)
more info ...
Related Pseudogenes: Actb-ps1   Actg-ps1   Gm14348   Gm14356   Gm14357   Gm14361   Gm14375   Gm14610   Gm14747   Gm15252   Gm15256   Gm15257   Gm15260   Gm15273   Gm15725   Gm16423   Gm17087   Gm17854   Gm17855   Gm17856   Gm17857   Gm17858   Gm17859   Gm17860   Gm17862   Gm17863   Gm17864   Gm17865   Gm17866   Gm17875   Gm17878   Gm17883   Gm4750   Gm4760   Gm4918   Gm5241   Gm6375   Gm7023   Gm9348  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl5142,903,115 - 142,906,754 (-)Ensembl
GRCm385142,903,115 - 142,907,976 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375143,664,795 - 143,668,403 (-)NCBIGRCm37mm9NCBIm37
MGSCv365143,168,256 - 143,171,864 (-)NCBImm8
Celera5139,951,533 - 139,955,141 (-)NCBICelera
Cytogenetic Map5 G2NCBI
cM Map581.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Actb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735802
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.