Hibadh (3-hydroxyisobutyrate dehydrogenase) - Rat Genome Database

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Gene: Hibadh (3-hydroxyisobutyrate dehydrogenase) Mus musculus
Analyze
Symbol: Hibadh
Name: 3-hydroxyisobutyrate dehydrogenase
RGD ID: 1332315
MGI Page MGI
Description: Predicted to enable 3-hydroxyisobutyrate dehydrogenase activity. Predicted to be involved in valine catabolic process. Predicted to act upstream of or within branched-chain amino acid catabolic process. Located in mitochondrion. Is expressed in several structures, including genitourinary system; gut; limb mesenchyme; liver and biliary system; and nervous system. Orthologous to human HIBADH (3-hydroxyisobutyrate dehydrogenase).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3-hydroxyisobutyrate dehydrogenase, mitochondrial; 6430402H10Rik; AI265272
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm11225   Gm18710  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,523,215 - 52,617,285 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,523,213 - 52,617,374 (-)EnsemblGRCm39 Ensembl
GRCm38652,546,230 - 52,640,300 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,546,228 - 52,640,389 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,496,224 - 52,590,294 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,475,808 - 52,569,878 (-)NCBIMGSCv36mm8
Celera653,069,543 - 53,163,491 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
acetamide  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chloroform  (ISO)
chromium trinitrate  (EXP)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
erythromycin estolate  (ISO)
ethanol  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
glafenine  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nafenopin  (ISO)
nickel atom  (ISO)
nitrogen dioxide  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phlorizin  (EXP)
potassium chromate  (EXP)
progesterone  (ISO)
quinidine  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (HDA,IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15509224   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:18614015   PMID:21677750   PMID:21873635   PMID:22496890   PMID:24194600   PMID:26398943   PMID:27626380   PMID:30550785   PMID:30973865   PMID:32325033  
PMID:36293380  


Genomics

Comparative Map Data
Hibadh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,523,215 - 52,617,285 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,523,213 - 52,617,374 (-)EnsemblGRCm39 Ensembl
GRCm38652,546,230 - 52,640,300 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,546,228 - 52,640,389 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,496,224 - 52,590,294 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,475,808 - 52,569,878 (-)NCBIMGSCv36mm8
Celera653,069,543 - 53,163,491 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.6NCBI
HIBADH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,525,442 - 27,662,883 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,525,442 - 27,662,883 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,565,061 - 27,702,502 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,531,586 - 27,669,127 (-)NCBINCBI36Build 36hg18NCBI36
Build 34727,338,302 - 27,475,842NCBI
Celera727,553,696 - 27,691,196 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,445,802 - 27,583,281 (-)NCBIHuRef
CHM1_1727,565,079 - 27,702,664 (-)NCBICHM1_1
T2T-CHM13v2.0727,661,820 - 27,799,261 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,616,251 - 27,753,745 (-)NCBI
Hibadh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,979,759 - 83,077,819 (-)NCBIGRCr8
mRatBN7.2481,649,180 - 81,747,244 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,649,175 - 81,780,617 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,863,552 - 86,961,661 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,638,929 - 82,737,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0481,065,988 - 81,164,230 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,604,369 - 82,702,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,604,373 - 82,702,429 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04147,270,733 - 147,368,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,850,300 - 80,948,361 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1481,134,949 - 81,232,983 (-)NCBI
Celera476,531,774 - 76,629,846 (-)NCBICelera
Cytogenetic Map4q24NCBI
Hibadh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541029,180,184 - 29,294,315 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541029,180,411 - 29,294,273 (-)NCBIChiLan1.0ChiLan1.0
HIBADH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2632,350,862 - 32,487,161 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,675,588 - 80,811,869 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0728,166,127 - 28,299,845 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,763,021 - 27,896,598 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,763,021 - 27,896,598 (-)Ensemblpanpan1.1panPan2
HIBADH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,672,294 - 40,780,608 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,673,008 - 40,780,516 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1440,103,065 - 40,211,269 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,612,124 - 40,720,480 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11440,724,156 - 40,832,851 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,410,011 - 40,517,904 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,768,329 - 40,876,417 (-)NCBIUU_Cfam_GSD_1.0
Hibadh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,907,096 - 85,008,177 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364784,118,752 - 4,219,908 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIBADH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1844,985,425 - 45,208,347 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11844,985,410 - 45,102,171 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21849,444,226 - 49,485,380 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIBADH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12130,708,862 - 30,848,158 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2130,708,943 - 30,848,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,892,111 - 74,031,577 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hibadh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247392,964,982 - 3,078,074 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247392,965,096 - 3,077,810 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hibadh
2666 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:298
Interacting mature miRNAs:342
Transcripts:ENSMUST00000031788, ENSMUST00000149471, ENSMUST00000155948
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
14696807Rbcn2_mrod bipolar cell number 2 (mouse)65118698056186985Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse

Markers in Region
AI265272  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,546,406 - 52,546,630UniSTSGRCm38
MGSCv37652,496,400 - 52,496,624UniSTSGRCm37
Celera653,069,719 - 53,069,943UniSTS
Cytogenetic Map6B3UniSTS
stSG611224  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,566,706 - 52,566,790UniSTSGRCm38
MGSCv37652,516,700 - 52,516,784UniSTSGRCm37
Celera653,089,908 - 53,089,992UniSTS
Celera13116,150,373 - 116,151,223UniSTS
Cytogenetic Map6B3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000031788   ⟹   ENSMUSP00000031788
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,523,213 - 52,617,374 (-)Ensembl
GRCm38.p6 Ensembl652,546,228 - 52,640,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,525,837 - 52,533,900 (-)Ensembl
GRCm38.p6 Ensembl652,548,852 - 52,556,915 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155948
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,523,681 - 52,607,243 (-)Ensembl
GRCm38.p6 Ensembl652,546,696 - 52,630,258 (-)Ensembl
RefSeq Acc Id: ENSMUST00000203504
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,531,399 - 52,533,502 (-)Ensembl
GRCm38.p6 Ensembl652,554,414 - 52,556,517 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205086
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,611,217 - 52,617,300 (-)Ensembl
GRCm38.p6 Ensembl652,634,232 - 52,640,315 (-)Ensembl
RefSeq Acc Id: NM_145567   ⟹   NP_663542
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39652,523,215 - 52,617,285 (-)NCBI
GRCm38652,546,230 - 52,640,300 (-)ENTREZGENE
MGSCv37652,496,224 - 52,590,294 (-)RGD
Celera653,069,543 - 53,163,491 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_663542 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH03914 (Get FASTA)   NCBI Sequence Viewer  
  BAC37162 (Get FASTA)   NCBI Sequence Viewer  
  BAF42049 (Get FASTA)   NCBI Sequence Viewer  
  EDK98682 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000031788
  ENSMUSP00000031788.9
GenBank Protein Q99L13 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_663542   ⟸   NM_145567
- Peptide Label: precursor
- UniProtKB: Q8BJY2 (UniProtKB/Swiss-Prot),   Q99L13 (UniProtKB/Swiss-Prot),   A0ZNJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000031788   ⟸   ENSMUST00000031788
Protein Domains
3-hydroxyisobutyrate dehydrogenase-like NAD-binding   6-phosphogluconate dehydrogenase NADP-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99L13-F1-model_v2 AlphaFold Q99L13 1-335 view protein structure

Promoters
RGD ID:6838876
Promoter ID:MM_KWN:46038
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   Kidney,   Liver
Transcripts:OTTMUST00000056971,   UC009BYX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36652,506,741 - 52,507,241 (-)MPROMDB
RGD ID:6839438
Promoter ID:MM_KWN:46039
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000056972
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36652,579,506 - 52,580,006 (-)MPROMDB
RGD ID:6839435
Promoter ID:MM_KWN:46041
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000056970
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36652,590,046 - 52,590,546 (-)MPROMDB
RGD ID:6889756
Promoter ID:EPDNEW_M8329
Type:initiation region
Name:Hibadh_1
Description:Mus musculus 3-hydroxyisobutyrate dehydrogenase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38652,640,319 - 52,640,379EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1889802 AgrOrtholog
Ensembl Genes ENSMUSG00000029776 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031788 ENTREZGENE
  ENSMUST00000031788.9 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 3-OH-isobutyrate_DH-rel_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6PGDH_NADP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HIBADH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HIBADH-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:58875 UniProtKB/Swiss-Prot
MGD MGI:1889802 ENTREZGENE
NCBI Gene 58875 ENTREZGENE
PANTHER 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NAD_binding_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hibadh PhenoGen
PIRSF HIBADH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE 3_HYDROXYISOBUT_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 3HIDH_MOUSE UniProtKB/Swiss-Prot
  A0ZNJ2 ENTREZGENE, UniProtKB/TrEMBL
  Q8BJY2 ENTREZGENE
  Q99L13 ENTREZGENE
UniProt Secondary Q8BJY2 UniProtKB/Swiss-Prot