CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | dihydrochalcones |
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Accession: | CHEBI:71230
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browse the term
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Definition: | Any ketone that is 1,3-diphenylpropanone and its derivatives obtained by substitution. |
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Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 protein] |
CTD |
PMID:25338943 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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F10 |
coagulation factor X |
multiple interactions |
ISO |
aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein] |
CTD |
PMID:25325928 |
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NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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F2 |
coagulation factor II |
multiple interactions |
ISO |
aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] |
CTD |
PMID:25325928 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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F5 |
coagulation factor V |
multiple interactions |
ISO |
aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] |
CTD |
PMID:25325928 |
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NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
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F7 |
coagulation factor VII |
multiple interactions |
ISO |
aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein] |
CTD |
PMID:25325928 |
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NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
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Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] |
CTD |
PMID:25338943 PMID:25655391 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il6 |
interleukin 6 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] |
CTD |
PMID:25655391 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:25655391 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:25655391 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA] |
CTD |
PMID:25655391 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
aspalathin inhibits the reaction [Glucose affects the localization of RELA protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein] |
CTD |
PMID:25338943 PMID:25655391 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Sele |
selectin E |
multiple interactions |
ISO |
aspalathin inhibits the reaction [Glucose results in increased expression of SELE protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein] |
CTD |
PMID:25338943 PMID:25655391 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] |
CTD |
PMID:25325928 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] |
CTD |
PMID:25655391 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; aspalathin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] |
CTD |
PMID:25325928 PMID:25655391 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
aspalathin inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] |
CTD |
PMID:25338943 PMID:25655391 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Aadacl2 |
arylacetamide deacetylase-like 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of AADACL2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:144,123,557...144,144,159
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Aass |
aminoadipate-semialdehyde synthase |
increases expression |
ISO |
avobenzone results in increased expression of AASS mRNA |
CTD |
PMID:31016361 |
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NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Abca12 |
ATP binding cassette subfamily A member 12 |
decreases expression |
ISO |
avobenzone results in decreased expression of ABCA12 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
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Abhd3 |
abhydrolase domain containing 3, phospholipase |
increases expression |
ISO |
avobenzone results in increased expression of ABHD3 mRNA |
CTD |
PMID:31016361 |
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NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428
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Acat2 |
acetyl-CoA acetyltransferase 2 |
increases expression |
ISO |
avobenzone results in increased expression of ACAT2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acly |
ATP citrate lyase |
increases expression |
ISO |
avobenzone results in increased expression of ACLY mRNA |
CTD |
PMID:31016361 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
avobenzone results in increased expression of ACSS2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
increases expression |
ISO |
avobenzone results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adgre5 |
adhesion G protein-coupled receptor E5 |
increases expression |
ISO |
avobenzone results in increased expression of ADGRE5 mRNA |
CTD |
PMID:31016361 |
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NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
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Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 affects the reaction [avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]] |
CTD |
PMID:31016361 PMID:32407875 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Afap1 |
actin filament associated protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of AFAP1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
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Aif1l |
allograft inflammatory factor 1-like |
decreases expression |
ISO |
avobenzone results in decreased expression of AIF1L mRNA |
CTD |
PMID:31016361 |
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NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023
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Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
avobenzone results in increased expression of AKR1C1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
avobenzone results in increased expression of AKR1C2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
avobenzone results in increased expression of AKR1C3 mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
increases expression |
ISO |
avobenzone results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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Ang |
angiogenin |
increases expression |
ISO |
avobenzone results in increased expression of ANG mRNA |
CTD |
PMID:31016361 |
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NCBI chr15:24,317,733...24,323,361
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Ank2 |
ankyrin 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of ANK2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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Antxr1 |
ANTXR cell adhesion molecule 1 |
increases expression |
ISO |
avobenzone results in increased expression of ANTXR1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
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Aopep |
aminopeptidase O |
decreases expression |
ISO |
avobenzone results in decreased expression of AOPEP mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:1,811,922...2,127,316
Ensembl chr17:1,811,980...2,127,331
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Ar |
androgen receptor |
affects binding multiple interactions |
ISO |
avobenzone binds to AR protein avobenzone binds to and results in decreased activity of AR protein |
CTD |
PMID:15537743 PMID:28115641 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Araf |
A-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
avobenzone results in increased expression of ARAF mRNA |
CTD |
PMID:31016361 |
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NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073
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Arhgap26 |
Rho GTPase activating protein 26 |
decreases expression |
ISO |
avobenzone results in decreased expression of ARHGAP26 mRNA |
CTD |
PMID:31016361 |
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NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
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Arid3b |
AT-rich interaction domain 3B |
increases expression |
ISO |
avobenzone results in increased expression of ARID3B mRNA |
CTD |
PMID:31016361 |
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NCBI chr 8:58,193,268...58,240,901
Ensembl chr 8:58,193,418...58,238,318
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Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
avobenzone results in decreased expression of ASNS mRNA |
CTD |
PMID:31016361 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Asph |
aspartate-beta-hydroxylase |
increases expression |
ISO |
avobenzone results in increased expression of ASPH mRNA |
CTD |
PMID:31016361 |
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NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876
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Asphd2 |
aspartate beta-hydroxylase domain containing 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of ASPHD2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr12:44,248,145...44,258,653
Ensembl chr12:44,248,145...44,257,772
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Ass1 |
argininosuccinate synthase 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of ASS1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atp10b |
ATPase phospholipid transporting 10B (putative) |
decreases expression |
ISO |
avobenzone results in decreased expression of ATP10B mRNA |
CTD |
PMID:31016361 |
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NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
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Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
increases expression |
ISO |
avobenzone results in increased expression of ATP6V0D2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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Bambi |
BMP and activin membrane-bound inhibitor |
decreases expression |
ISO |
avobenzone results in decreased expression of BAMBI mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
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Bbs12 |
Bardet-Biedl syndrome 12 |
decreases expression |
ISO |
avobenzone results in decreased expression of BBS12 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:120,203,396...120,221,024
Ensembl chr 2:120,203,428...120,219,255
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Bcar3 |
BCAR3 adaptor protein, NSP family member |
increases expression |
ISO |
avobenzone results in increased expression of BCAR3 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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Bcdin3d |
BCDIN3 domain containing RNA methyltransferase |
decreases expression |
ISO |
avobenzone results in decreased expression of BCDIN3D mRNA |
CTD |
PMID:31016361 |
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NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115
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Bcl6b |
BCL6B, transcription repressor |
decreases expression |
ISO |
avobenzone results in decreased expression of BCL6B mRNA |
CTD |
PMID:31016361 |
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NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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Brd3os |
BRD3 opposite strand |
decreases expression |
ISO |
avobenzone results in decreased expression of BRD3OS mRNA |
CTD |
PMID:31016361 |
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NCBI chr 3:10,769,815...10,771,860
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Btbd7 |
BTB domain containing 7 |
decreases expression multiple interactions |
ISO |
avobenzone results in decreased expression of BTBD7 mRNA avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA]; IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA] |
CTD |
PMID:29981360 |
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NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405
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C5h8orf88 |
similar to human chromosome 8 open reading frame 88 |
increases expression |
ISO |
avobenzone results in increased expression of C8ORF88 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 5:28,330,167...28,355,691
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C8h11orf71 |
similar to human chromosome 11 open reading frame 71 |
decreases expression |
ISO |
avobenzone results in decreased expression of C11ORF71 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 8:48,838,556...48,838,970
Ensembl chr 8:48,838,100...48,842,270
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Calhm6 |
calcium homeostasis modulator family member 6 |
increases expression |
ISO |
avobenzone results in increased expression of CALHM6 mRNA |
CTD |
PMID:31016361 |
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NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278
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Calml5 |
calmodulin-like 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of CALML5 mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:66,394,433...66,395,390
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Calr |
calreticulin |
increases expression |
ISO |
avobenzone results in increased expression of CALR mRNA |
CTD |
PMID:31016361 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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Camk1d |
calcium/calmodulin-dependent protein kinase ID |
decreases expression |
ISO |
avobenzone results in decreased expression of CAMK1D mRNA |
CTD |
PMID:31016361 |
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NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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Cbs |
cystathionine beta synthase |
decreases expression |
ISO |
avobenzone results in decreased expression of CBS mRNA |
CTD |
PMID:31016361 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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Ccbe1 |
collagen and calcium binding EGF domains 1 |
increases expression |
ISO |
avobenzone results in increased expression of CCBE1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400
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Ccdc125 |
coiled-coil domain containing 125 |
decreases expression |
ISO |
avobenzone results in decreased expression of CCDC125 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152
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Ccdc167 |
coiled-coil domain containing 167 |
increases expression |
ISO |
avobenzone results in increased expression of CCDC167 mRNA |
CTD |
PMID:31016361 |
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NCBI chr20:7,763,927...7,782,090
Ensembl chr20:7,751,782...7,781,613
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Ccdc18 |
coiled-coil domain containing 18 |
decreases expression |
ISO |
avobenzone results in decreased expression of CCDC18 mRNA |
CTD |
PMID:31016361 |
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NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
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Ccdc71 |
coiled-coil domain containing 71 |
increases expression |
ISO |
avobenzone results in increased expression of CCDC71 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 8:109,146,650...109,161,749
Ensembl chr 8:109,146,359...109,165,216
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Ccn1 |
cellular communication network factor 1 |
increases expression |
ISO |
avobenzone results in increased expression of CCN1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Ccna1 |
cyclin A1 |
decreases expression |
ISO |
avobenzone results in decreased expression of CCNA1 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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Ccng2 |
cyclin G2 |
increases expression |
ISO |
avobenzone results in increased expression of CCNG2 mRNA |
CTD |
PMID:31016361 |
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NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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Cdk19 |
cyclin-dependent kinase 19 |
increases expression |
ISO |
avobenzone results in increased expression of CDK19 mRNA |
CTD |
PMID:31016361 |
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NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628
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G |
Cdkn2aipnl |
CDKN2A interacting protein N-terminal like |
increases expression |
ISO |
avobenzone results in increased expression of CDKN2AIPNL mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:36,231,134...36,240,569
Ensembl chr10:36,231,087...36,240,564
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Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
decreases expression |
ISO |
avobenzone results in decreased expression of CDKN2B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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Cdkn2d |
cyclin dependent kinase inhibitor 2D |
increases expression |
ISO |
avobenzone results in increased expression of CDKN2D mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
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Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
avobenzone results in decreased expression of CEBPA mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cenpe |
centromere protein E |
decreases expression |
ISO |
avobenzone results in decreased expression of CENPE mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
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Cep104 |
centrosomal protein 104 |
increases expression |
ISO |
avobenzone results in increased expression of CEP104 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:164,534,773...164,567,260
Ensembl chr 5:164,534,782...164,567,248
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Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
avobenzone results in increased expression of CES1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Cfap70 |
cilia and flagella associated protein 70 |
decreases expression |
ISO |
avobenzone results in decreased expression of CFAP70 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of CHAC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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G |
Chac2 |
ChaC glutathione specific gamma-glutamylcyclotransferase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of CHAC2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
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G |
Chml |
CHM like Rab escort protein |
decreases expression |
ISO |
avobenzone results in decreased expression of CHML mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:87,613,610...87,615,475
Ensembl chr13:87,589,298...87,619,862
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G |
Cited4 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
increases expression |
ISO |
avobenzone results in increased expression of CITED4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
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G |
Cldn19 |
claudin 19 |
decreases expression |
ISO |
avobenzone results in decreased expression of CLDN19 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227
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G |
Clhc1 |
clathrin heavy chain linker domain containing 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of CLHC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:103,288,116...103,328,725
Ensembl chr14:103,288,134...103,328,715
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G |
Clip2 |
CAP-GLY domain containing linker protein 2 |
increases expression |
ISO |
avobenzone results in increased expression of CLIP2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
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G |
Clk3 |
CDC-like kinase 3 |
increases expression |
ISO |
avobenzone results in increased expression of CLK3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181
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G |
Cmklr2 |
chemerin chemokine-like receptor 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of CMKLR2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:64,583,310...64,618,127
Ensembl chr 9:64,585,594...64,586,655
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G |
Cmtm7 |
CKLF-like MARVEL transmembrane domain containing 7 |
increases expression |
ISO |
avobenzone results in increased expression of CMTM7 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621
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G |
Cnpy3 |
canopy FGF signaling regulator 3 |
increases expression |
ISO |
avobenzone results in increased expression of CNPY3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:14,233,478...14,247,847
Ensembl chr 9:14,233,428...14,247,831
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G |
Cnst |
consortin, connexin sorting protein |
increases expression |
ISO |
avobenzone results in increased expression of CNST mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:91,296,740...91,373,531
Ensembl chr13:91,296,142...91,373,531
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G |
Cox19 |
cytochrome c oxidase assembly factor COX19 |
decreases expression |
ISO |
avobenzone results in decreased expression of COX19 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014
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G |
Crebrf |
CREB3 regulatory factor |
increases expression |
ISO |
avobenzone results in increased expression of CREBRF mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
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G |
Creg2 |
cellular repressor of E1A-stimulated genes 2 |
increases expression |
ISO |
avobenzone results in increased expression of CREG2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
avobenzone results in increased expression of CYP1A1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of CYP4F12 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
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G |
Cyp4f40 |
cytochrome P450, family 4, subfamily f, polypeptide 40 |
increases expression |
ISO |
avobenzone results in increased expression of CYP4F11 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression |
ISO |
avobenzone results in increased expression of DBP mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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G |
Dcbld2 |
discoidin, CUB and LCCL domain containing 2 |
increases expression |
ISO |
avobenzone results in increased expression of DCBLD2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:42,125,787...42,179,927
Ensembl chr11:42,125,787...42,179,697
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G |
Ddx54 |
DEAD-box helicase 54 |
increases expression |
ISO |
avobenzone results in increased expression of DDX54 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:35,934,713...35,949,956
Ensembl chr12:35,934,716...35,972,523
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G |
Ddx59 |
DEAD-box helicase 59 |
increases expression |
ISO |
avobenzone results in increased expression of DDX59 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:47,876,258...47,901,214
Ensembl chr13:47,876,261...47,901,214
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G |
Decr2 |
2,4-dienoyl-CoA reductase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of DECR2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479
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G |
Dennd5b |
DENN domain containing 5B |
increases expression |
ISO |
avobenzone results in increased expression of DENND5B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:181,959,597...182,089,661
Ensembl chr 4:181,961,386...182,089,362
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of DGAT2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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|
G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
avobenzone results in increased expression of DHCR7 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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|
G |
Dhrs9 |
dehydrogenase/reductase 9 |
decreases expression |
ISO |
avobenzone results in decreased expression of DHRS9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
increases expression |
ISO |
avobenzone results in increased expression of DKK1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
|
|
G |
Dkk3 |
dickkopf WNT signaling pathway inhibitor 3 |
increases expression |
ISO |
avobenzone results in increased expression of DKK3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
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|
G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
avobenzone results in increased expression of DNAJB9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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|
G |
Dnajc30 |
DnaJ heat shock protein family (Hsp40) member C30 |
decreases expression |
ISO |
avobenzone results in decreased expression of DNAJC30 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:21,628,323...21,629,389
Ensembl chr12:21,626,450...21,629,408
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|
G |
Dok7 |
docking protein 7 |
increases expression |
ISO |
avobenzone results in increased expression of DOK7 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386
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G |
Dsc1 |
desmocollin 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of DSC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494
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G |
Dsg1 |
desmoglein 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of DSG1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443
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G |
Dusp10 |
dual specificity phosphatase 10 |
increases expression |
ISO |
avobenzone results in increased expression of DUSP10 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
avobenzone results in increased expression of DUSP4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
Ebp |
EBP, cholestenol delta-isomerase |
increases expression |
ISO |
avobenzone results in increased expression of EBP mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Echdc3 |
enoyl CoA hydratase domain containing 3 |
increases expression |
ISO |
avobenzone results in increased expression of ECHDC3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
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|
G |
Ecm2 |
extracellular matrix protein 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of ECM2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
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G |
Egfr |
epidermal growth factor receptor |
increases expression |
ISO |
avobenzone results in increased expression of EGFR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eid2 |
EP300 interacting inhibitor of differentiation 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of EID2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:83,538,217...83,542,262
|
|
G |
Eif2ak4 |
eukaryotic translation initiation factor 2 alpha kinase 4 |
increases expression |
ISO |
avobenzone results in increased expression of EIF2AK4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
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|
G |
Elp1 |
elongator acetyltransferase complex subunit 1 |
increases expression |
ISO |
avobenzone results in increased expression of ELP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
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|
G |
Emp3 |
epithelial membrane protein 3 |
increases expression |
ISO |
avobenzone results in increased expression of EMP3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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G |
Epha4 |
Eph receptor A4 |
decreases expression |
ISO |
avobenzone results in decreased expression of EPHA4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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G |
Ephx3 |
epoxide hydrolase 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of EPHX3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122
|
|
G |
Epm2aip1 |
EPM2A interacting protein 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of EPM2AIP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871
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G |
Eri1 |
exoribonuclease 1 |
increases expression |
ISO |
avobenzone results in increased expression of ERI1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:56,724,101...56,744,228
Ensembl chr16:56,724,115...56,744,226
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
avobenzone binds to and results in increased activity of ESR1 protein |
CTD |
PMID:15537743 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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|
G |
Etv4 |
ETS variant transcription factor 4 |
increases expression |
ISO |
avobenzone results in increased expression of ETV4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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|
G |
F2r |
coagulation factor II (thrombin) receptor |
increases expression |
ISO |
avobenzone results in increased expression of F2R mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
|
|
G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA] |
CTD |
PMID:31016361 PMID:32407875 |
|
NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
|
|
G |
Fam185a |
family with sequence similarity 185, member A |
decreases expression |
ISO |
avobenzone results in decreased expression of FAM185A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:13,542,022...13,662,967
Ensembl chr 4:13,608,464...13,662,967
|
|
G |
Fam217b |
family with sequence similarity 217, member B |
increases expression |
ISO |
avobenzone results in increased expression of FAM217B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:165,505,574...165,515,273
Ensembl chr 3:165,501,532...165,513,377
|
|
G |
Fam241a |
family with sequence similarity 241 member A |
decreases expression |
ISO |
avobenzone results in decreased expression of FAM241A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242
|
|
G |
Fam3c |
FAM3 metabolism regulating signaling molecule C |
increases expression |
ISO |
avobenzone results in increased expression of FAM3C mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
|
|
G |
Fam43a |
family with sequence similarity 43, member A |
decreases expression |
ISO |
avobenzone results in decreased expression of FAM43A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
|
|
G |
Fanci |
FA complementation group I |
increases expression |
ISO |
avobenzone results in increased expression of FANCI mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
|
|
G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
avobenzone results in increased expression of FASN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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|
G |
Fbn2 |
fibrillin 2 |
increases expression |
ISO |
avobenzone results in increased expression of FBN2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
|
|
G |
Fbxl20 |
F-box and leucine-rich repeat protein 20 |
increases expression |
ISO |
avobenzone results in increased expression of FBXL20 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162
|
|
G |
Fbxo32 |
F-box protein 32 |
increases expression |
ISO |
avobenzone results in increased expression of FBXO32 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
|
|
G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression |
ISO |
avobenzone results in increased expression of FDFT1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
|
|
G |
Fdps |
farnesyl diphosphate synthase |
increases expression |
ISO |
avobenzone results in increased expression of FDPS mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
|
|
G |
Fgd6 |
FYVE, RhoGEF and PH domain containing 6 |
increases expression |
ISO |
avobenzone results in increased expression of FGD6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
|
|
G |
Fibin |
fin bud initiation factor homolog |
decreases expression |
ISO |
avobenzone results in decreased expression of FIBIN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
|
|
G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
avobenzone results in decreased expression of FILIP1L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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|
G |
Flg |
filaggrin |
decreases expression |
ISO |
avobenzone results in decreased expression of FLG mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:178,888,688...178,912,731
|
|
G |
Flg2 |
filaggrin 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of FLG2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:178,789,792...178,802,232
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
avobenzone results in decreased expression of FOS mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G |
Foxk1 |
forkhead box K1 |
increases expression |
ISO |
avobenzone results in increased expression of FOXK1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:12,110,119...12,175,089
Ensembl chr12:12,115,950...12,175,089
|
|
G |
Foxp2 |
forkhead box P2 |
decreases expression |
ISO |
avobenzone results in decreased expression of FOXP2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
|
|
G |
Fry |
FRY microtubule binding protein |
decreases expression |
ISO |
avobenzone results in decreased expression of FRY mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
|
|
G |
Fzd2 |
frizzled class receptor 2 |
increases expression |
ISO |
avobenzone results in increased expression of FZD2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
|
|
G |
Gabarapl1 |
GABA type A receptor associated protein like 1 |
increases expression |
ISO |
avobenzone results in increased expression of GABARAPL1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
|
|
G |
Gask1b |
golgi associated kinase 1B |
increases expression |
ISO |
avobenzone results in increased expression of GASK1B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
|
|
G |
Gcat |
glycine C-acetyltransferase |
increases expression |
ISO |
avobenzone results in increased expression of GCAT mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
|
|
G |
Gchfr |
GTP cyclohydrolase I feedback regulator |
increases expression |
ISO |
avobenzone results in increased expression of GCHFR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
|
|
G |
Gdap1 |
ganglioside-induced differentiation-associated-protein 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of GDAP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061
|
|
G |
Gen1 |
GEN1 Holliday junction 5' flap endonuclease |
decreases expression |
ISO |
avobenzone results in decreased expression of GEN1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
|
|
G |
Ggact |
gamma-glutamylamine cyclotransferase |
decreases expression |
ISO |
avobenzone results in decreased expression of GGACT mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455
|
|
G |
Gjb6 |
gap junction protein, beta 6 |
decreases expression |
ISO |
avobenzone results in decreased expression of GJB6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:31,284,562...31,295,010
Ensembl chr15:31,284,419...31,294,582
|
|
G |
Glul |
glutamate-ammonia ligase |
increases expression |
ISO |
avobenzone results in increased expression of GLUL mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
|
|
G |
Gne |
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
increases expression |
ISO |
avobenzone results in increased expression of GNE mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
|
|
G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
avobenzone results in increased expression of GPNMB mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation |
ISO |
avobenzone results in increased phosphorylation of GSK3B protein |
CTD |
PMID:29981360 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
|
|
G |
Gspt2 |
G1 to S phase transition 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of GSPT2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:59,587,237...59,589,758
Ensembl chr X:59,587,276...59,594,162
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
avobenzone inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
|
|
G |
Gtf3c2 |
general transcription factor IIIC subunit 2 |
increases expression |
ISO |
avobenzone results in increased expression of GTF3C2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:25,196,439...25,221,338
Ensembl chr 6:25,197,268...25,220,490
|
|
G |
Habp4 |
hyaluronan binding protein 4 |
increases expression |
ISO |
avobenzone results in increased expression of HABP4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
|
|
G |
Harbi1 |
harbinger transposase derived 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of HARBI1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:77,681,431...77,689,749
Ensembl chr 3:77,681,431...77,689,724
|
|
G |
Heg1 |
heart development protein with EGF-like domains 1 |
increases expression |
ISO |
avobenzone results in increased expression of HEG1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051
|
|
G |
Henmt1 |
HEN methyltransferase 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of HENMT1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:196,585,732...196,603,700
Ensembl chr 2:196,586,797...196,599,738
|
|
G |
Hes5 |
hes family bHLH transcription factor 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of HES5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
avobenzone results in increased expression of HMGCR mRNA |
CTD |
PMID:31016361 PMID:32407875 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
avobenzone results in increased expression of HMGCS1 mRNA |
CTD |
PMID:31016361 PMID:32407875 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
|
|
G |
Homez |
homeobox and leucine zipper encoding |
decreases expression |
ISO |
avobenzone results in decreased expression of HOMEZ mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:28,321,633...28,339,486
Ensembl chr15:28,320,819...28,339,745
|
|
G |
Hp1bp3 |
heterochromatin protein 1, binding protein 3 |
increases expression |
ISO |
avobenzone results in increased expression of HP1BP3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000
|
|
G |
Hs3st6 |
heparan sulfate-glucosamine 3-sulfotransferase 6 |
decreases expression |
ISO |
avobenzone results in decreased expression of HS3ST6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:13,781,999...13,788,133
Ensembl chr10:13,781,993...13,788,133
|
|
G |
Hsd17b14 |
hydroxysteroid (17-beta) dehydrogenase 14 |
increases expression |
ISO |
avobenzone results in increased expression of HSD17B14 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:96,029,290...96,039,088
Ensembl chr 1:96,029,284...96,039,883
|
|
G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of ID1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
|
|
G |
Id4 |
inhibitor of DNA binding 4 |
decreases expression |
ISO |
avobenzone results in decreased expression of ID4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
|
|
G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
increases expression |
ISO |
avobenzone results in increased expression of IDI1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
|
|
G |
Idnk |
Idnk, gluconokinase |
decreases expression |
ISO |
avobenzone results in decreased expression of IDNK mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:6,483,575...6,490,780
Ensembl chr17:6,483,576...6,490,905
|
|
G |
Ifi27 |
interferon, alpha-inducible protein 27 |
multiple interactions increases expression |
ISO |
avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA]; IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA] avobenzone results in increased expression of IFI27 mRNA |
CTD |
PMID:29981360 |
|
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
|
|
G |
Ifi27l2b |
interferon, alpha-inducible protein 27 like 2B |
increases expression |
ISO |
avobenzone results in increased expression of IFI27L2 mRNA |
CTD |
PMID:29981360 |
|
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
|
|
G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of IFIT3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
|
|
G |
Ift70b |
intraflagellar transport 70B |
decreases expression |
ISO |
avobenzone results in decreased expression of IFT70B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:60,855,809...60,858,380
Ensembl chr 3:60,855,575...60,858,389
|
|
G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
increases expression |
ISO |
avobenzone results in increased expression of IGFBP7 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
|
|
G |
Ikbip |
IKBKB interacting protein |
increases expression |
ISO |
avobenzone results in increased expression of IKBIP mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:25,579,759...25,598,548
Ensembl chr 7:25,579,832...25,605,162
|
|
G |
Il18r1 |
interleukin 18 receptor 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of IL18R1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
|
|
G |
Il33 |
interleukin 33 |
increases expression |
ISO |
avobenzone results in increased expression of IL33 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
|
|
G |
Impa2 |
inositol monophosphatase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of IMPA2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
|
|
G |
Inf2 |
inverted formin 2 |
increases expression |
ISO |
avobenzone results in increased expression of INF2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941
|
|
G |
Ing1 |
inhibitor of growth family, member 1 |
increases expression |
ISO |
avobenzone results in increased expression of ING1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:77,937,276...77,945,320
Ensembl chr16:77,937,279...77,946,264
|
|
G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA] |
CTD |
PMID:32407875 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[avobenzone co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARA mRNA; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; T 0070907 affects the reaction [avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]] |
CTD |
PMID:31016361 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
|
|
G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
avobenzone results in increased expression of INSIG1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
|
|
G |
Irs2 |
insulin receptor substrate 2 |
increases expression |
ISO |
avobenzone results in increased expression of IRS2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
|
|
G |
Irx3 |
iroquois homeobox 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of IRX3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
|
|
G |
Itpkb |
inositol-trisphosphate 3-kinase B |
increases expression |
ISO |
avobenzone results in increased expression of ITPKB mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
|
|
G |
Jmy |
junction mediating and regulatory protein, p53 cofactor |
increases expression |
ISO |
avobenzone results in increased expression of JMY mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006
|
|
G |
Jpx |
JPX transcript, XIST activator |
decreases expression |
ISO |
avobenzone results in decreased expression of JPX mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:68,511,491...68,665,132
|
|
G |
Jrk |
Jrk helix-turn-helix protein |
increases expression |
ISO |
avobenzone results in increased expression of JRK mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371
|
|
G |
Jrkl |
JRK-like |
decreases expression |
ISO |
avobenzone results in decreased expression of JRKL mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068
|
|
G |
Kcnj5 |
potassium inwardly-rectifying channel, subfamily J, member 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of KCNJ5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
|
|
G |
Kctd11 |
potassium channel tetramerization domain containing 11 |
decreases expression |
ISO |
avobenzone results in decreased expression of KCTD11 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760
|
|
G |
Kdelr3 |
KDEL endoplasmic reticulum protein retention receptor 3 |
increases expression |
ISO |
avobenzone results in increased expression of KDELR3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600
|
|
G |
Klf10 |
KLF transcription factor 10 |
decreases expression |
ISO |
avobenzone results in decreased expression of KLF10 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
|
|
G |
Klf16 |
KLF transcription factor 16 |
increases expression |
ISO |
avobenzone results in increased expression of KLF16 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317
|
|
G |
Klhl24 |
kelch-like family member 24 |
increases expression |
ISO |
avobenzone results in increased expression of KLHL24 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:80,843,621...80,877,693
Ensembl chr11:80,846,755...80,877,636
|
|
G |
Klhl9 |
kelch-like family member 9 |
decreases expression |
ISO |
avobenzone results in decreased expression of KLHL9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:103,333,747...103,337,931
|
|
G |
Kmt2d |
lysine methyltransferase 2D |
increases expression |
ISO |
avobenzone results in increased expression of KMT2D mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
|
|
G |
Krcc1 |
lysine-rich coiled-coil 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of KRCC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:103,261,566...103,274,672
Ensembl chr 4:103,261,536...103,277,156
|
|
G |
Krt1 |
keratin 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of KRT1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
|
|
G |
Krtap8-1 |
keratin associated protein 8-1 |
decreases expression |
ISO |
avobenzone results in decreased expression of KRTAP8-1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:28,717,314...28,720,574
Ensembl chr11:28,718,125...28,718,310
|
|
G |
Kyat1 |
kynurenine aminotransferase 1 |
increases expression |
ISO |
avobenzone results in increased expression of KYAT1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
|
|
G |
L3mbtl1 |
L3MBTL histone methyl-lysine binding protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of L3MBTL1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
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G |
Lactb |
lactamase, beta |
increases expression |
ISO |
avobenzone results in increased expression of LACTB mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:67,571,504...67,587,592
Ensembl chr 8:67,571,500...67,587,539
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G |
Lamp3 |
lysosomal-associated membrane protein 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of LAMP3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
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G |
Lcmt2 |
leucine carboxyl methyltransferase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of LCMT2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084
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Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
avobenzone results in increased expression of LDLR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lima1 |
LIM domain and actin binding 1 |
increases expression |
ISO |
avobenzone results in increased expression of LIMA1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
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G |
Lix1l |
limb and CNS expressed 1 like |
increases expression |
ISO |
avobenzone results in increased expression of LIX1L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916
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G |
Lmln |
leishmanolysin like peptidase |
decreases expression |
ISO |
avobenzone results in decreased expression of LMLN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:67,656,241...67,725,889
Ensembl chr11:67,658,152...67,724,243
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G |
Lnx1 |
ligand of numb-protein X 1 |
increases expression |
ISO |
avobenzone results in increased expression of LNX1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:33,514,429...33,617,086
Ensembl chr14:33,514,436...33,617,086
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G |
LOC100125364 |
hypothetical protein LOC100125364 |
decreases expression |
ISO |
avobenzone results in decreased expression of C6ORF120 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:55,950,419...55,953,173
Ensembl chr 1:55,949,814...55,963,333
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G |
LOC120095898 |
paired immunoglobulin-like type 2 receptor beta |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF37A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:17,744,315...17,756,074
Ensembl chr12:17,752,830...17,755,922
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G |
LOC120103107 |
PRAME family member 12-like |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF585B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:156,009,794...156,012,390
Ensembl chr 5:156,009,836...156,012,357
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G |
LOC688765 |
hypothetical protein LOC688765 |
decreases expression |
ISO |
avobenzone results in decreased expression of C8ORF48 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:55,244,744...55,246,642
Ensembl chr16:55,236,322...55,246,650
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G |
Loricrin |
loricrin cornified envelope precursor protein |
decreases expression |
ISO |
avobenzone results in decreased expression of LORICRIN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
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G |
Lpcat4 |
lysophosphatidylcholine acyltransferase 4 |
increases expression |
ISO |
avobenzone results in increased expression of LPCAT4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
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G |
Lpin1 |
lipin 1 |
increases expression |
ISO |
avobenzone results in increased expression of LPIN1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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|
G |
Lrrc8d |
leucine rich repeat containing 8 VRAC subunit D |
decreases expression |
ISO |
avobenzone results in decreased expression of LRRC8D mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877
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G |
Lss |
lanosterol synthase |
increases expression |
ISO |
avobenzone results in increased expression of LSS mRNA |
CTD |
PMID:31016361 |
|
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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G |
Luc7l |
LUC7-like |
increases expression |
ISO |
avobenzone results in increased expression of LUC7L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112
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G |
Ly9 |
lymphocyte antigen 9 |
increases expression |
ISO |
avobenzone results in increased expression of LY9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:84,081,283...84,100,757
Ensembl chr13:84,079,458...84,100,823
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G |
Lynx1 |
Ly6/neurotoxin 1 |
increases expression |
ISO |
avobenzone results in increased expression of LYNX1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023
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G |
Lypd6b |
Ly6/Plaur domain containing 6B |
decreases expression |
ISO |
avobenzone results in decreased expression of LYPD6B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770
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G |
Mab21l3 |
mab-21 like 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of MAB21L3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652
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|
G |
Mafb |
MAF bZIP transcription factor B |
decreases expression |
ISO |
avobenzone results in decreased expression of MAFB mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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|
G |
Maged2 |
MAGE family member D2 |
increases expression |
ISO |
avobenzone results in increased expression of MAGED2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:19,733,593...19,741,769
Ensembl chr X:19,733,597...19,740,477
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G |
Magee1 |
MAGE family member E1 |
increases expression |
ISO |
avobenzone results in increased expression of MAGEE1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:70,189,242...70,192,789
Ensembl chr X:70,189,187...70,192,810
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|
G |
Maml3 |
mastermind-like transcriptional coactivator 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of MAML3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:135,722,585...136,136,975
Ensembl chr 2:135,721,021...136,137,814
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|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
avobenzone results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:29981360 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
ISO |
avobenzone results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:29981360 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mblac2 |
metallo-beta-lactamase domain containing 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of MBLAC2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:11,986,075...12,028,882
Ensembl chr 2:11,986,027...12,030,950
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|
G |
Mcm4 |
minichromosome maintenance complex component 4 |
increases expression |
ISO |
avobenzone results in increased expression of MCM4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
|
|
G |
Mcm5 |
minichromosome maintenance complex component 5 |
increases expression |
ISO |
avobenzone results in increased expression of MCM5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
|
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
avobenzone results in increased expression of MDM2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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|
G |
Mettl21a |
methyltransferase 21A, HSPA lysine |
increases expression |
ISO |
avobenzone results in increased expression of METTL21A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550
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|
G |
Mfap3l |
microfibril associated protein 3 like |
decreases expression |
ISO |
avobenzone results in decreased expression of MFAP3L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
|
|
G |
Mib1 |
MIB E3 ubiquitin protein ligase 1 |
increases expression |
ISO |
avobenzone results in increased expression of MIB1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
|
|
G |
Micall2 |
MICAL-like 2 |
increases expression |
ISO |
avobenzone results in increased expression of MICALL2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:14,899,151...14,927,949
Ensembl chr12:14,899,157...14,927,946
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|
G |
Micb |
MHC class I polypeptide-related sequence B |
increases expression |
ISO |
avobenzone results in increased expression of MICB mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827
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|
G |
Mill1 |
MHC I like leukocyte 1 |
increases expression |
ISO |
avobenzone results in increased expression of MICA mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
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|
G |
Mmp3 |
matrix metallopeptidase 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of MMP3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
|
|
G |
Mnd1 |
meiotic nuclear divisions 1 |
increases expression |
ISO |
avobenzone results in increased expression of MND1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:169,433,538...169,496,081
Ensembl chr 2:169,433,540...169,496,096
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|
G |
Mocs3 |
molybdenum cofactor synthesis 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of MOCS3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890
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|
G |
Morf4l1 |
mortality factor 4 like 1 |
increases expression |
ISO |
avobenzone results in increased expression of MORF4L1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519
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|
G |
Mrpl39 |
mitochondrial ribosomal protein L39 |
increases expression |
ISO |
avobenzone results in increased expression of MRPL39 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:23,779,655...23,795,146
Ensembl chr11:23,779,662...23,795,125
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|
G |
Msantd3 |
Myb/SANT DNA binding domain containing 3 |
increases expression |
ISO |
avobenzone results in increased expression of MSANTD3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859
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|
G |
Msto1 |
misato mitochondrial distribution and morphology regulator 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of MSTO1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:174,305,945...174,310,230
Ensembl chr 2:174,301,861...174,310,216
|
|
G |
Mt1-ps3 |
metallothionein 1, pseudogene 3 |
increases expression |
ISO |
avobenzone results in increased expression of MT1E mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
avobenzone results in increased expression of MT2A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Muc15 |
mucin 15, cell surface associated |
decreases expression |
ISO |
avobenzone results in decreased expression of MUC15 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:97,294,728...97,308,641
Ensembl chr 3:97,294,783...97,307,090
|
|
G |
Mvd |
mevalonate diphosphate decarboxylase |
increases expression |
ISO |
avobenzone results in increased expression of MVD mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
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G |
Myo3b |
myosin IIIB |
increases expression |
ISO |
avobenzone results in increased expression of MYO3B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:54,873,704...55,226,189
Ensembl chr 3:54,820,251...55,227,373
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|
G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
increases expression |
ISO |
avobenzone results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
|
|
G |
Ncoa5 |
nuclear receptor coactivator 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of NCOA5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553
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|
G |
Ndufa4l2 |
NDUFA4, mitochondrial complex associated like 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of NDUFA4L2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
ISO |
avobenzone results in decreased expression of NEDD4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nhlrc2 |
NHL repeat containing 2 |
increases expression |
ISO |
avobenzone results in increased expression of NHLRC2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:255,589,742...255,650,448
Ensembl chr 1:255,589,742...255,651,408
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G |
Nipal3 |
NIPA-like domain containing 3 |
increases expression |
ISO |
avobenzone results in increased expression of NIPAL3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351
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|
G |
Nkpd1 |
NTPase, KAP family P-loop domain containing 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of NKPD1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:79,165,642...79,175,126
Ensembl chr 1:79,167,130...79,174,234
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G |
Noct |
nocturnin |
increases expression |
ISO |
avobenzone results in increased expression of NOCT mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
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|
G |
Npas2 |
neuronal PAS domain protein 2 |
increases expression |
ISO |
avobenzone results in increased expression of NPAS2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
|
|
G |
Npepl1 |
aminopeptidase-like 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of NPEPL1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:162,893,891...162,906,492
Ensembl chr 3:162,893,943...162,906,492
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
avobenzone results in increased expression of NQO1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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|
G |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
increases expression |
ISO |
avobenzone results in increased expression of NR1D2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
affects binding |
ISO |
avobenzone binds to NR3C1 protein |
CTD |
PMID:28115641 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
|
|
G |
Nub1 |
negative regulator of ubiquitin-like proteins 1 |
increases expression |
ISO |
avobenzone results in increased expression of NUB1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694
|
|
G |
Nwd2 |
NACHT and WD repeat domain containing 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of NWD2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299
|
|
G |
Obsl1 |
obscurin like cytoskeletal adaptor 1 |
increases expression |
ISO |
avobenzone results in increased expression of OBSL1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:76,967,802...76,993,565
Ensembl chr 9:76,974,253...76,993,560
|
|
G |
Ostm1 |
osteoclastogenesis associated transmembrane protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of OSTM1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023
|
|
G |
Otud1 |
OTU deubiquitinase 1 |
increases expression |
ISO |
avobenzone results in increased expression of OTUD1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:82,259,881...82,262,774
Ensembl chr17:82,259,840...82,262,995
|
|
G |
P2rx7 |
purinergic receptor P2X 7 |
decreases expression |
ISO |
avobenzone results in decreased expression of P2RX7 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
|
|
G |
P2ry1 |
purinergic receptor P2Y1 |
decreases expression |
ISO |
avobenzone results in decreased expression of P2RY1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
|
|
G |
Pappa2 |
pappalysin 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of PAPPA2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:70,873,918...71,147,874
Ensembl chr13:70,876,794...71,147,779
|
|
G |
Papss2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
increases expression |
ISO |
avobenzone results in increased expression of PAPSS2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
|
|
G |
Pard3 |
par-3 family cell polarity regulator |
increases expression |
ISO |
avobenzone results in increased expression of PARD3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
|
|
G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
decreases expression |
ISO |
avobenzone results in decreased expression of PCK2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
|
|
G |
Pclo |
piccolo (presynaptic cytomatrix protein) |
decreases expression |
ISO |
avobenzone results in decreased expression of PCLO mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885
|
|
G |
Pcna |
proliferating cell nuclear antigen |
decreases expression |
ISO |
avobenzone results in decreased expression of PCNA protein |
CTD |
PMID:29981360 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
|
|
G |
PCOLCE2 |
procollagen C-endopeptidase enhancer 2 |
increases expression |
ISO |
avobenzone results in increased expression of PCOLCE2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
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G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
increases expression |
ISO |
avobenzone results in increased expression of PCSK9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
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G |
Pdcd5 |
programmed cell death 5 |
increases expression |
ISO |
avobenzone results in increased expression of PDCD5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
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G |
Pde5a |
phosphodiesterase 5A |
increases expression |
ISO |
avobenzone results in increased expression of PDE5A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
increases expression |
ISO |
avobenzone results in increased expression of PDIA4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
increases expression |
ISO |
avobenzone results in increased expression of PDK1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
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G |
Pdp2 |
pyruvate dehydrogenase phosphatase catalytic subunit 2 |
increases expression |
ISO |
avobenzone results in increased expression of PDP2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
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G |
Pdxdc1 |
pyridoxal-dependent decarboxylase domain containing 1 |
increases expression |
ISO |
avobenzone results in increased expression of PDXDC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520
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G |
Pet100 |
PET100 cytochrome c oxidase chaperone |
increases expression |
ISO |
avobenzone results in increased expression of PET100 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:1,679,805...1,682,540
Ensembl chr12:1,679,859...1,682,540
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G |
Pex13 |
peroxisomal biogenesis factor 13 |
increases expression |
ISO |
avobenzone results in increased expression of PEX13 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:97,602,829...97,621,233
Ensembl chr14:97,603,539...97,621,262
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G |
Pfdn4 |
prefoldin subunit 4 |
increases expression |
ISO |
avobenzone results in increased expression of PFDN4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:159,303,064...159,311,221
Ensembl chr 3:159,303,071...159,311,219
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G |
Phactr3 |
phosphatase and actin regulator 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of PHACTR3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153
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G |
Phex |
phosphate regulating endopeptidase X-linked |
decreases expression |
ISO |
avobenzone results in decreased expression of PHEX mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
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G |
Phtf2 |
putative homeodomain transcription factor 2 |
increases expression |
ISO |
avobenzone results in increased expression of PHTF2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:14,215,190...14,330,513
Ensembl chr 4:14,215,263...14,330,513
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G |
Pi4k2a |
phosphatidylinositol 4-kinase type 2 alpha |
increases expression |
ISO |
avobenzone results in increased expression of PI4K2A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337
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G |
Pidd1 |
p53-induced death domain protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of PIDD1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
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G |
Pigm |
phosphatidylinositol glycan anchor biosynthesis, class M |
decreases expression |
ISO |
avobenzone results in decreased expression of PIGM mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:84,838,329...84,842,026
Ensembl chr13:84,838,175...84,843,381
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
increases expression |
ISO |
avobenzone results in increased expression of PIK3C2A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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G |
Pik3ip1 |
phosphoinositide-3-kinase interacting protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of PIK3IP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:78,203,539...78,216,616
Ensembl chr14:78,204,053...78,216,608
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G |
Plau |
plasminogen activator, urokinase |
increases expression |
ISO |
avobenzone results in increased expression of PLAU mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plekhg3 |
pleckstrin homology and RhoGEF domain containing G3 |
increases expression |
ISO |
avobenzone results in increased expression of PLEKHG3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:95,265,756...95,308,952
Ensembl chr 6:95,266,058...95,310,359
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G |
Plin2 |
perilipin 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of PLIN2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plpp6 |
phospholipid phosphatase 6 |
decreases expression |
ISO |
avobenzone results in decreased expression of PLPP6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949
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G |
Pnisr |
PNN interacting serine and arginine rich protein |
increases expression |
ISO |
avobenzone results in increased expression of PNISR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:35,395,965...35,422,852
Ensembl chr 5:35,395,965...35,422,844
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|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression multiple interactions |
ISO |
avobenzone results in increased expression of PPARA mRNA [avobenzone co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARA mRNA |
CTD |
PMID:31016361 PMID:32407875 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO |
avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA] avobenzone results in increased expression of PPARG mRNA |
CTD |
PMID:31016361 PMID:32407875 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Ppfibp1 |
PPFIA binding protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of PPFIBP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
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G |
Ppm1k |
protein phosphatase, Mg2+/Mn2+ dependent, 1K |
increases expression |
ISO |
avobenzone results in increased expression of PPM1K mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152
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G |
Ppp1r18 |
protein phosphatase 1, regulatory subunit 18 |
increases expression |
ISO |
avobenzone results in increased expression of PPP1R18 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
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G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
decreases expression |
ISO |
avobenzone results in decreased expression of PPP1R3C mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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G |
Prkg1 |
protein kinase cGMP-dependent 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of PRKG1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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G |
Prmt2 |
protein arginine methyltransferase 2 |
increases expression |
ISO |
avobenzone results in increased expression of PRMT2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
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G |
Prmt6 |
protein arginine methyltransferase 6 |
decreases expression |
ISO |
avobenzone results in decreased expression of PRMT6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648
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G |
Prmt8 |
protein arginine methyltransferase 8 |
decreases expression |
ISO |
avobenzone results in decreased expression of PRMT8 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930
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G |
Prss23 |
serine protease 23 |
decreases expression |
ISO |
avobenzone results in decreased expression of PRSS23 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091
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G |
Psat1 |
phosphoserine aminotransferase 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of PSAT1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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G |
Pskh1 |
protein serine kinase H1 |
decreases expression |
ISO |
avobenzone results in decreased expression of PSKH1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:33,794,919...33,827,040
Ensembl chr19:33,794,935...33,827,032
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G |
Ptafr |
platelet-activating factor receptor |
increases expression |
ISO |
avobenzone results in increased expression of PTAFR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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G |
Ptpdc1 |
protein tyrosine phosphatase domain containing 1 |
increases expression |
ISO |
avobenzone results in increased expression of PTPDC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:16,028,964...16,076,512
Ensembl chr17:16,049,382...16,076,512
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G |
Qprt |
quinolinate phosphoribosyltransferase |
increases expression |
ISO |
avobenzone results in increased expression of QPRT mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
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G |
Rab11fip4 |
RAB11 family interacting protein 4 |
increases expression |
ISO |
avobenzone results in increased expression of RAB11FIP4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759
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G |
Rac2 |
Rac family small GTPase 2 |
increases expression |
ISO |
avobenzone results in increased expression of RAC2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
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|
G |
Rad18 |
RAD18 E3 ubiquitin protein ligase |
increases expression |
ISO |
avobenzone results in increased expression of RAD18 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
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G |
Raet1e |
retinoic acid early transcript 1E |
decreases expression |
ISO |
avobenzone results in decreased expression of RAET1E mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
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G |
Ranbp1 |
RAN binding protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of RANBP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
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G |
Ranbp6 |
RAN binding protein 6 |
decreases expression |
ISO |
avobenzone results in decreased expression of RANBP6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942
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G |
Rasgrp1 |
RAS guanyl releasing protein 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of RASGRP1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
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G |
Rassf10 |
Ras association domain family member 10 |
decreases expression |
ISO |
avobenzone results in decreased expression of RASSF10 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:167,058,245...167,063,591
Ensembl chr 1:167,058,099...167,063,572
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G |
Rbl2 |
RB transcriptional corepressor like 2 |
increases expression |
ISO |
avobenzone results in increased expression of RBL2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
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G |
Rbm45 |
RNA binding motif protein 45 |
decreases expression |
ISO |
avobenzone results in decreased expression of RBM45 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:61,305,973...61,320,950
Ensembl chr 3:61,305,924...61,320,952
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G |
Rbm5 |
RNA binding motif protein 5 |
increases expression |
ISO |
avobenzone results in increased expression of RBM5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430
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G |
Rgs5 |
regulator of G-protein signaling 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of RGS5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
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G |
Rnase4 |
ribonuclease A family member 4 |
increases expression |
ISO |
avobenzone results in increased expression of RNASE4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:24,312,765...24,330,116
Ensembl chr15:24,312,464...24,330,117
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G |
Rnf6 |
ring finger protein 6 |
increases expression |
ISO |
avobenzone results in increased expression of RNF6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:8,816,777...8,826,870
Ensembl chr12:8,816,833...8,826,847
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G |
Rps6 |
ribosomal protein S6 |
increases phosphorylation |
ISO |
avobenzone results in increased phosphorylation of RPS6 protein |
CTD |
PMID:29981360 |
|
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6ka6 |
ribosomal protein S6 kinase A6 |
decreases expression |
ISO |
avobenzone results in decreased expression of RPS6KA6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:76,354,824...76,454,484
Ensembl chr X:76,353,760...76,454,484
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
increases phosphorylation |
ISO |
avobenzone results in increased phosphorylation of RPS6KB1 protein |
CTD |
PMID:29981360 |
|
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Rptn |
repetin |
decreases expression |
ISO |
avobenzone results in decreased expression of RPTN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910
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G |
Rragd |
Ras-related GTP binding D |
increases expression |
ISO |
avobenzone results in increased expression of RRAGD mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
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G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
increases expression |
ISO |
avobenzone results in increased expression of RSAD2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
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G |
Rsbn1l |
round spermatid basic protein 1-like |
increases expression |
ISO |
avobenzone results in increased expression of RSBN1L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:14,138,076...14,203,972
Ensembl chr 4:14,139,031...14,201,147
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G |
Rundc1 |
RUN domain containing 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of RUNDC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:86,361,635...86,375,446
Ensembl chr10:86,361,051...86,370,878
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G |
Samd13 |
sterile alpha motif domain containing 13 |
decreases expression |
ISO |
avobenzone results in decreased expression of SAMD13 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:235,534,699...235,540,527
Ensembl chr 2:235,534,702...235,567,615
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G |
Samd4a |
sterile alpha motif domain containing 4A |
increases expression |
ISO |
avobenzone results in increased expression of SAMD4A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
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G |
Samd9 |
sterile alpha motif domain containing 9 |
decreases expression |
ISO |
avobenzone results in decreased expression of SAMD9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:31,164,639...31,184,325
Ensembl chr 4:31,164,510...31,184,322
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G |
Samd9l1 |
sterile alpha motif domain containing 9 like 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of SAMD9L mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415
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G |
Scara3 |
scavenger receptor class A, member 3 |
increases expression |
ISO |
avobenzone results in increased expression of SCARA3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
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G |
Scd |
stearoyl-CoA desaturase |
increases expression |
ISO |
avobenzone results in increased expression of SCD mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scml1 |
Scm polycomb group protein like 1 |
increases expression |
ISO |
avobenzone results in increased expression of SCML1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:32,893,100...32,912,686
Ensembl chr X:32,894,327...32,911,366
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|
G |
Sdf2l1 |
stromal cell-derived factor 2-like 1 |
increases expression |
ISO |
avobenzone results in increased expression of SDF2L1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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G |
Sec24d |
SEC24 homolog D, COPII coat complex component |
increases expression |
ISO |
avobenzone results in increased expression of SEC24D mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587
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G |
Sema6d |
semaphorin 6D |
decreases expression |
ISO |
avobenzone results in decreased expression of SEMA6D mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094
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G |
Sephs2 |
selenophosphate synthetase 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of SEPHS2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
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|
G |
Sft2d3 |
SFT2 domain containing 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of SFT2D3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:23,537,105...23,539,305
Ensembl chr18:23,537,105...23,539,305
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|
G |
Sh3bgr |
SH3 domain binding glutamate-rich protein |
decreases expression |
ISO |
avobenzone results in decreased expression of SH3BGR mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853
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|
G |
Slc12a6 |
solute carrier family 12, member 6 |
increases expression |
ISO |
avobenzone results in increased expression of SLC12A6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258
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G |
Slc16a9 |
solute carrier family 16, member 9 |
decreases expression |
ISO |
avobenzone results in decreased expression of SLC16A9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr20:18,336,142...18,377,154
Ensembl chr20:18,335,862...18,377,022
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Slc17a5 |
solute carrier family 17 member 5 |
increases expression |
ISO |
avobenzone results in increased expression of SLC17A5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:79,394,416...79,429,387
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Slc25a37 |
solute carrier family 25 member 37 |
increases expression |
ISO |
avobenzone results in increased expression of SLC25A37 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
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Slc2a12 |
solute carrier family 2 member 12 |
increases expression |
ISO |
avobenzone results in increased expression of SLC2A12 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971
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G |
Slc2a3 |
solute carrier family 2 member 3 |
increases expression |
ISO |
avobenzone results in increased expression of SLC2A3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc2a8 |
solute carrier family 2 member 8 |
increases expression |
ISO |
avobenzone results in increased expression of SLC2A8 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464
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G |
Slc33a1 |
solute carrier family 33 member 1 |
increases expression |
ISO |
avobenzone results in increased expression of SLC33A1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:148,415,660...148,438,182
Ensembl chr 2:148,415,666...148,437,758
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Slc5a3 |
solute carrier family 5 member 3 |
increases expression |
ISO |
avobenzone results in increased expression of SLC5A3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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G |
Slc6a6 |
solute carrier family 6 member 6 |
increases expression |
ISO |
avobenzone results in increased expression of SLC6A6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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G |
Smim5 |
small integral membrane protein 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of SMIM5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813
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G |
Smtn |
smoothelin |
increases expression |
ISO |
avobenzone results in increased expression of SMTN mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
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G |
Snrnp27 |
small nuclear ribonucleoprotein U4/U6.U5 subunit 27 |
increases expression |
ISO |
avobenzone results in increased expression of SNRNP27 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:119,123,676...119,133,234
Ensembl chr 4:119,121,877...119,133,234
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G |
Socs3 |
suppressor of cytokine signaling 3 |
increases expression |
ISO |
avobenzone results in increased expression of SOCS3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Socs4 |
suppressor of cytokine signaling 4 |
decreases expression |
ISO |
avobenzone results in decreased expression of SOCS4 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494
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G |
Sox9 |
SRY-box transcription factor 9 |
increases expression |
ISO |
avobenzone results in increased expression of SOX9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases expression |
ISO |
avobenzone results in increased expression of SPARC mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Spink6 |
serine peptidase inhibitor, Kazal type 6 |
increases expression |
ISO |
avobenzone results in increased expression of SPINK6 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr18:36,397,910...36,409,819
Ensembl chr18:36,397,910...36,409,819
|
|
G |
Sqle |
squalene epoxidase |
increases expression |
ISO |
avobenzone results in increased expression of SQLE mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
avobenzone results in increased expression of SQSTM1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Stc2 |
stanniocalcin 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of STC2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
|
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G |
Stk32c |
serine/threonine kinase 32C |
increases expression |
ISO |
avobenzone results in increased expression of STK32C mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:193,900,718...193,981,723
Ensembl chr 1:193,900,718...193,981,723
|
|
G |
Stx19 |
syntaxin 19 |
decreases expression |
ISO |
avobenzone results in decreased expression of STX19 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:172,855...178,053
Ensembl chr11:171,395...179,191
|
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G |
Sugct |
succinylCoA:glutarate-CoA transferase |
increases expression |
ISO |
avobenzone results in increased expression of SUGCT mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
|
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G |
Sult1e1 |
sulfotransferase family 1E member 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of SULT1E1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
|
|
G |
Suox |
sulfite oxidase |
decreases expression |
ISO |
avobenzone results in decreased expression of SUOX mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
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|
G |
Sybu |
syntabulin |
decreases expression |
ISO |
avobenzone results in decreased expression of SYBU mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828
|
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G |
Sync |
syncoilin, intermediate filament protein |
decreases expression |
ISO |
avobenzone results in decreased expression of SYNC mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659
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|
G |
Taf13 |
TATA-box binding protein associated factor 13 |
increases expression |
ISO |
avobenzone results in increased expression of TAF13 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
|
|
G |
Tbc1d2 |
TBC1 domain family, member 2 |
increases expression |
ISO |
avobenzone results in increased expression of TBC1D2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:60,884,114...60,931,717
Ensembl chr 5:60,884,124...60,931,352
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G |
Tent5c |
terminal nucleotidyltransferase 5C |
increases expression |
ISO |
avobenzone results in increased expression of TENT5C mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
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|
G |
Tfpi2 |
tissue factor pathway inhibitor 2 |
increases expression |
ISO |
avobenzone results in increased expression of TFPI2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
|
|
G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
increases expression |
ISO |
avobenzone results in increased expression of TGFBR2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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|
G |
Tgm1 |
transglutaminase 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of TGM1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
|
|
G |
Themis2 |
thymocyte selection associated family member 2 |
increases expression |
ISO |
avobenzone results in increased expression of THEMIS2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:144,991,110...145,006,347
Ensembl chr 5:144,991,112...145,006,400
|
|
G |
Tm9sf1 |
transmembrane 9 superfamily member 1 |
increases expression |
ISO |
avobenzone results in increased expression of TM9SF1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:29,127,585...29,135,349
Ensembl chr15:29,127,584...29,135,349
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|
G |
Tmem139 |
transmembrane protein 139 |
decreases expression |
ISO |
avobenzone results in decreased expression of TMEM139 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:71,147,072...71,149,151
Ensembl chr 4:71,146,724...71,167,399
|
|
G |
Tmem185b |
transmembrane protein 185B |
decreases expression |
ISO |
avobenzone results in decreased expression of TMEM185B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr13:30,647,533...30,650,864
Ensembl chr13:30,647,482...30,650,858
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G |
Tmem250 |
transmembrane protein 250 |
decreases expression |
ISO |
avobenzone results in decreased expression of TMEM250 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349
|
|
G |
Tmem67 |
transmembrane protein 67 |
decreases expression |
ISO |
avobenzone results in decreased expression of TMEM67 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
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|
G |
Tmem97 |
transmembrane protein 97 |
increases expression |
ISO |
avobenzone results in increased expression of TMEM97 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
|
|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein] |
CTD |
PMID:31016361 |
|
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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|
G |
Tnfsf9 |
TNF superfamily member 9 |
increases expression |
ISO |
avobenzone results in increased expression of TNFSF9 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
|
|
G |
Top3b |
DNA topoisomerase III beta |
increases expression |
ISO |
avobenzone results in increased expression of TOP3B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:84,097,018...84,125,474
Ensembl chr11:84,097,026...84,125,392
|
|
G |
Tram1l1 |
translocation associated membrane protein 1-like 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of TRAM1L1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:212,511,130...212,513,311
|
|
G |
Trim25 |
tripartite motif-containing 25 |
decreases expression |
ISO |
avobenzone results in decreased expression of TRIM25 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
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G |
Trim69 |
tripartite motif-containing 69 |
decreases expression |
ISO |
avobenzone results in decreased expression of TRIM69 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:109,111,468...109,135,255
Ensembl chr 3:109,111,468...109,132,037
|
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G |
Tsc22d3 |
TSC22 domain family, member 3 |
increases expression |
ISO |
avobenzone results in increased expression of TSC22D3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:104,217,898...104,277,935
Ensembl chr X:104,217,925...104,276,861
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G |
Tsen2 |
tRNA splicing endonuclease subunit 2 |
decreases expression |
ISO |
avobenzone results in decreased expression of TSEN2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
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|
G |
Tspan1 |
tetraspanin 1 |
increases expression |
ISO |
avobenzone results in increased expression of TSPAN1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:129,646,139...129,659,383
Ensembl chr 5:129,646,993...129,652,017
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G |
Tspyl5 |
TSPY-like 5 |
decreases expression |
ISO |
avobenzone results in decreased expression of TSPYL5 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:64,881,092...64,885,538
Ensembl chr 7:64,884,225...64,885,457
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|
G |
Ttbk2 |
tau tubulin kinase 2 |
increases expression |
ISO |
avobenzone results in increased expression of TTBK2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
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|
G |
Ttc7b |
tetratricopeptide repeat domain 7B |
increases expression |
ISO |
avobenzone results in increased expression of TTC7B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:119,587,389...119,799,155
Ensembl chr 6:119,587,390...119,799,330
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G |
Ttc9c |
tetratricopeptide repeat domain 9C |
increases expression |
ISO |
avobenzone results in increased expression of TTC9C mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:205,701,768...205,712,782
Ensembl chr 1:205,701,768...205,712,773
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G |
Tubgcp3 |
tubulin, gamma complex associated protein 3 |
increases expression |
ISO |
avobenzone results in increased expression of TUBGCP3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
avobenzone results in increased expression of TXNRD1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Txnrd2 |
thioredoxin reductase 2 |
increases expression |
ISO |
avobenzone results in increased expression of TXNRD2 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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G |
Uqcc1 |
ubiquinol-cytochrome c reductase complex assembly factor 1 |
increases expression |
ISO |
avobenzone results in increased expression of UQCC1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 3:144,353,276...144,445,810
Ensembl chr 3:144,353,287...144,445,711
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G |
Usp12 |
ubiquitin specific peptidase 12 |
increases expression |
ISO |
avobenzone results in increased expression of USP12 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656
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|
G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
avobenzone results in increased expression of VEGFA protein |
CTD |
PMID:25617811 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
|
|
G |
Wdhd1 |
WD repeat and HMG-box DNA binding protein 1 |
increases expression |
ISO |
avobenzone results in increased expression of WDHD1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096
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G |
Wdr5b |
WD repeat domain 5B |
decreases expression |
ISO |
avobenzone results in decreased expression of WDR5B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr11:64,710,945...64,712,804
Ensembl chr11:64,710,355...64,712,807
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G |
Wnt9a |
Wnt family member 9A |
decreases expression |
ISO |
avobenzone results in decreased expression of WNT9A mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
|
|
G |
Xaf1 |
XIAP associated factor 1 |
decreases expression |
ISO |
avobenzone results in decreased expression of XAF1 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:56,917,284...56,929,791
Ensembl chr10:56,917,121...56,929,770
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|
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Xdh |
xanthine dehydrogenase |
increases expression |
ISO |
avobenzone results in increased expression of XDH mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
|
|
G |
Xk |
X-linked Kx blood group antigen, Kell and VPS13A binding protein |
decreases expression |
ISO |
avobenzone results in decreased expression of XK mRNA |
CTD |
PMID:31016361 |
|
NCBI chr X:13,436,412...13,472,830
Ensembl chr X:13,436,418...13,472,830
|
|
G |
Zbed3 |
zinc finger, BED-type containing 3 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZBED3 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:26,587,620...26,600,177
Ensembl chr 2:26,587,572...26,600,386
|
|
G |
Zbtb10 |
zinc finger and BTB domain containing 10 |
increases expression |
ISO |
avobenzone results in increased expression of ZBTB10 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 2:92,475,254...92,509,857
Ensembl chr 2:92,479,014...92,512,515
|
|
G |
Zbtb44 |
zinc finger and BTB domain containing 44 |
increases expression |
ISO |
avobenzone results in increased expression of ZBTB44 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163
|
|
G |
Zdhhc21 |
zinc finger DHHC-type palmitoyltransferase 21 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZDHHC21 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:97,227,621...97,286,866
Ensembl chr 5:97,229,345...97,286,537
|
|
G |
Zfp112 |
zinc finger protein 112 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF112 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:79,676,933...79,691,994
Ensembl chr 1:79,676,839...79,691,994
|
|
G |
Zfp260 |
zinc finger protein 260 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF260 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:85,336,567...85,349,896
Ensembl chr 1:85,336,618...85,350,067
|
|
G |
Zfp418 |
zinc finger protein 418 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF416 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242
|
|
G |
Zfp518b |
zinc finger protein 518B |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF518B mRNA |
CTD |
PMID:31016361 |
|
NCBI chr14:72,121,085...72,140,479
Ensembl chr14:72,121,112...72,140,481
|
|
G |
Zfp605 |
zinc finger protein 605 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF605 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr12:46,542,771...46,575,074
Ensembl chr12:46,545,073...46,575,828
|
|
G |
Zfp606 |
zinc finger protein 606 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF606 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072
|
|
G |
Zfp618 |
zinc finger protein 618 |
increases expression |
ISO |
avobenzone results in increased expression of ZNF618 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:76,398,514...76,564,837
Ensembl chr 5:76,398,366...76,564,834
|
|
G |
Zfp623 |
zinc finger protein 623 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF623 mRNA |
CTD |
PMID:31016361 |
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NCBI chr 7:107,627,296...107,636,254
Ensembl chr 7:107,627,267...107,636,321
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G |
Zfp69 |
zinc finger protein 69 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZFP69 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 5:134,502,002...134,516,428
Ensembl chr 5:134,501,998...134,514,358
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G |
Zfp74 |
zinc finger protein 74 |
increases expression |
ISO |
avobenzone results in increased expression of ZNF569 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 1:85,158,159...85,183,407
Ensembl chr 1:85,158,980...85,183,522
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G |
Zfp870 |
zinc finger protein 870 |
increases expression |
ISO |
avobenzone results in increased expression of ZNF670 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813
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G |
Zfp879 |
zinc finger protein 879 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF879 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr10:35,148,679...35,158,674
Ensembl chr10:35,148,679...35,158,674
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G |
Zfp951 |
zinc finger protein 951 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZNF844 mRNA |
CTD |
PMID:31016361 |
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NCBI chr14:5,032,494...5,048,775
Ensembl chr14:5,033,734...5,048,756
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G |
Znrd1as |
zinc ribbon domain containing 1 antisense |
decreases expression |
ISO |
avobenzone results in decreased expression of POLR1HASP mRNA |
CTD |
PMID:31016361 |
|
NCBI chr 9:16,098,624...16,099,790
Ensembl chr 9:16,098,624...16,099,790
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G |
Zscan26 |
zinc finger and SCAN domain containing 26 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZSCAN26 mRNA |
CTD |
PMID:31016361 |
|
NCBI chr17:43,148,063...43,168,070
Ensembl chr17:43,148,079...43,168,070
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G |
Zscan29 |
zinc finger and SCAN domain containing 29 |
decreases expression |
ISO |
avobenzone results in decreased expression of ZSCAN29 mRNA |
CTD |
PMID:31016361 |
|
Ensembl chr 3:108,131,018...108,140,486
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of CASP3 protein] |
CTD |
PMID:24530446 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of CASP8 protein] |
CTD |
PMID:24530446 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Cat |
catalase |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT protein] |
CTD |
PMID:24530446 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] |
CTD |
PMID:24530446 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein] |
CTD |
PMID:24530446 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein] |
CTD |
PMID:24530446 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] |
CTD |
PMID:24530446 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Tas1r2 |
taste 1 receptor member 2 |
multiple interactions |
ISO |
lactisole inhibits the reaction [neohesperidin dihydrochalcone results in increased activity of [TAS1R3 protein binds to TAS1R2 protein]]; neohesperidin dihydrochalcone results in increased activity of [TAS1R3 protein binds to TAS1R2 protein] |
CTD |
PMID:17935609 |
|
NCBI chr 5:151,909,648...151,925,345
Ensembl chr 5:151,830,701...151,925,345
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G |
Tas1r3 |
taste 1 receptor member 3 |
multiple interactions affects binding |
ISO |
lactisole inhibits the reaction [neohesperidin dihydrochalcone results in increased activity of [TAS1R3 protein binds to TAS1R2 protein]]; neohesperidin dihydrochalcone binds to and results in increased activity of TAS1R3 protein; neohesperidin dihydrochalcone results in increased activity of [TAS1R3 protein binds to TAS1R2 protein] neohesperidin dihydrochalcone binds to TAS1R3 protein |
CTD |
PMID:17935609 PMID:20173092 |
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NCBI chr 5:166,469,589...166,472,742
Ensembl chr 5:166,469,589...166,472,742
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G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO |
[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Phloretin] results in increased activity of ACHE protein |
CTD |
PMID:33410021 |
|
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased secretion of ADIPOQ protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ADIPOQ mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of ADIPOQ mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased secretion of ADIPOQ protein] |
CTD |
PMID:32408695 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
affects binding |
EXP |
Phloretin binds to AFP protein |
CTD |
PMID:23013281 PMID:25349334 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in decreased expression of AKT1 protein |
CTD |
PMID:34896434 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ANGPTL4 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of ANGPTL4 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of ANGPTL4 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of ANGPTL4 mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Aqp9 |
aquaporin 9 |
multiple interactions decreases activity |
EXP ISO |
Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenic Acid analog]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] Phloretin results in decreased activity of AQP9 protein |
CTD |
PMID:9733774 PMID:12606488 PMID:21259319 PMID:28798983 |
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NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] |
CTD |
PMID:32408695 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein] |
CTD |
PMID:34896434 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
ISO |
Phloretin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of BCHE protein] |
CTD |
PMID:33410021 |
|
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein] |
CTD |
PMID:34896434 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] |
CTD |
PMID:32408695 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BCL2L11 protein] |
CTD |
PMID:32408695 |
|
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in increased cleavage of CASP3 protein |
CTD |
PMID:34896434 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in decreased expression of and results in increased cleavage of CASP9 protein |
CTD |
PMID:34896434 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein] |
CTD |
PMID:34896434 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of CCL2 mRNA |
CTD |
PMID:24707119 PMID:32408695 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein] |
CTD |
PMID:24707119 |
|
NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in increased expression of CDKN1A protein |
CTD |
PMID:34896434 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions |
EXP |
Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] |
CTD |
PMID:12606488 |
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NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] |
CTD |
PMID:24707119 |
|
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
CTD |
PMID:17177569 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein |
CTD |
PMID:34896434 |
|
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Phloretin binds to and results in increased activity of ESR1 protein |
CTD |
PMID:9751507 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding |
ISO |
Phloretin binds to and results in increased activity of ESR2 protein Phloretin binds to ESR2 protein |
CTD |
PMID:9751507 PMID:12224631 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Acetaminophen results in increased activity of GPT protein] |
CTD |
PMID:30287234 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases activity |
ISO |
Phloretin results in decreased activity of GSK3B protein |
CTD |
PMID:16968061 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of HIF1A mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of HIF1A mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein] |
CTD |
PMID:24707119 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein] |
CTD |
PMID:24707119 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] |
CTD |
PMID:24707119 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Uric Acid results in increased secretion of IL1B protein] 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL1B mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of IL1B mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL1B mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL1B mRNA |
CTD |
PMID:21051542 PMID:32408695 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1RN protein] |
CTD |
PMID:24707119 |
|
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of IL6 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of IL6 mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein] |
CTD |
PMID:24707119 PMID:32408695 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] |
CTD |
PMID:17965850 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
affects response to substance |
EXP |
KCNMA1 mRNA affects the susceptibility to Phloretin |
CTD |
PMID:19247476 |
|
NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
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G |
Lep |
leptin |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of LEP mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of LEP mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of LEP mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of LEP mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of LEP mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] affects the expression of LEP mRNA; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of LEP protein] |
CTD |
PMID:32408695 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Ltf |
lactotransferrin |
increases expression |
EXP |
Phloretin results in increased expression of LTF protein |
CTD |
PMID:24487097 |
|
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
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G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
EXP |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MKI67 protein] |
CTD |
PMID:34896434 |
|
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MMP9 protein] |
CTD |
PMID:34896434 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
[Ruthenium binds to Phloretin] which results in decreased expression of MTOR protein |
CTD |
PMID:34896434 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Phloretin] results in increased expression of NFE2L2 mRNA |
CTD |
PMID:33410021 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of NFKB1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of NFKB1 mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of NFKB1 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of NFKB1 mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression multiple interactions |
ISO |
Phloretin results in decreased expression of NOS3 mRNA Phloretin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA] |
CTD |
PMID:20021702 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of PPARG mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]]; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] |
CTD |
PMID:32408695 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Shbg |
sex hormone binding globulin |
affects binding |
ISO |
Phloretin binds to SHBG protein |
CTD |
PMID:25349334 |
|
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Slc14a1 |
solute carrier family 14 member 1 (Kidd blood group) |
multiple interactions |
EXP |
Phloretin inhibits the reaction [SLC14A1 protein results in increased transport of Urea] |
CTD |
PMID:8982255 |
|
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
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G |
Slc14a2 |
solute carrier family 14 member 2 |
multiple interactions |
EXP |
Phloretin inhibits the reaction [SLC14A2 protein results in increased transport of Urea] |
CTD |
PMID:11181411 |
|
NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
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G |
Slc16a1 |
solute carrier family 16 member 1 |
multiple interactions |
EXP |
[[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate; [Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate |
CTD |
PMID:17108059 |
|
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
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G |
Slc16a2 |
solute carrier family 16 member 2 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] |
CTD |
PMID:28119167 |
|
NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions decreases activity |
ISO |
Phloretin inhibits the reaction [SLC2A1 protein affects the transport of Glucose] Phloretin results in decreased activity of SLC2A1 protein |
CTD |
PMID:14642735 |
|
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions decreases expression |
ISO EXP |
Phloretin inhibits the reaction [Fluorouracil promotes the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]]; Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose] Phloretin results in decreased expression of SLC2A2 protein Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose] |
CTD |
PMID:15986457 PMID:17272349 PMID:26616219 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc2a9 |
solute carrier family 2 member 9 |
multiple interactions |
ISO |
Phloretin inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] |
CTD |
PMID:19587147 |
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NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981
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G |
Slc9a1 |
solute carrier family 9 member A1 |
multiple interactions decreases activity |
ISO |
Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]] Phloretin results in decreased activity of SLC9A1 protein; Phloretin results in decreased activity of SLC9A1 protein alternative form |
CTD |
PMID:12765964 |
|
NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
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G |
Slc9b2 |
solute carrier family 9 member B2 |
decreases activity |
ISO |
Phloretin results in decreased activity of SLC9B2 protein |
CTD |
PMID:18000046 |
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NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of TNF mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of TNF mRNA |
CTD |
PMID:32408695 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
EXP ISO |
[Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein] [Ruthenium binds to Phloretin] which results in increased expression of TP53 protein |
CTD |
PMID:34896434 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT1A1 protein |
CTD |
PMID:35868516 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT1A3 protein |
CTD |
PMID:35868516 |
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NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT1A6 protein |
CTD |
PMID:35868516 |
|
NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a8 |
UDP glucuronosyltransferase family 1 member A8 |
increases glucuronidation decreases activity |
ISO |
UGT1A8 protein results in increased glucuronidation of Phloretin Phloretin results in decreased activity of UGT1A8 protein |
CTD |
PMID:14557274 PMID:35868516 |
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NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT1A9 protein |
CTD |
PMID:35868516 |
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NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt2b1 |
UDP glucuronosyltransferase 2 family, polypeptide B1 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT2B17 protein |
CTD |
PMID:35868516 |
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NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
decreases activity |
ISO |
Phloretin results in decreased activity of UGT2B7 protein |
CTD |
PMID:35868516 |
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NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of VEGFA protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of VEGFA mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of VEGFA mRNA; Phloretin promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of VEGFA protein] [Ruthenium binds to Phloretin] which results in decreased expression of VEGFA protein |
CTD |
PMID:32408695 PMID:34896434 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Abat |
4-aminobutyrate aminotransferase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ABAT mRNA |
CTD |
PMID:22538082 |
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NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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G |
Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
increases expression |
ISO |
Phlorhizin results in increased expression of ACAA1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACAA2 mRNA |
CTD |
PMID:22538082 |
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NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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G |
Acad8 |
acyl-CoA dehydrogenase family, member 8 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACAD8 mRNA |
CTD |
PMID:22538082 |
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NCBI chr 8:25,382,271...25,406,429
Ensembl chr 8:25,382,273...25,406,414
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G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACAD9 mRNA |
CTD |
PMID:22538082 |
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NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACADL mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACADM mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACAT1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Aco1 |
aconitase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACO1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Acox1 |
acyl-CoA oxidase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACOX1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACOX2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ACSL1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Actb |
actin, beta |
increases expression |
ISO |
Phlorhizin results in increased expression of ACTB mRNA |
CTD |
PMID:22538082 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ADH5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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G |
Adhfe1 |
alcohol dehydrogenase, iron containing, 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ADHFE1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA |
CTD |
PMID:32408695 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of AKR1A1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Akr7a2 |
aldo-keto reductase family 7, member A2 |
increases expression |
ISO |
Phlorhizin results in increased expression of AKR7A2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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G |
Alb |
albumin |
multiple interactions |
ISO |
Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] |
CTD |
PMID:16313995 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases expression increases expression |
ISO |
Phlorhizin results in decreased expression of ALDH2 mRNA Phlorhizin results in increased expression of ALDH2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldh3a2 |
aldehyde dehydrogenase 3 family, member A2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ALDH3A2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
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G |
Aldh4a1 |
aldehyde dehydrogenase 4 family, member A1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ALDH4A1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345
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G |
Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ALDH6A1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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G |
Aldh7a1 |
aldehyde dehydrogenase 7 family, member A1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ALDH7A1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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G |
Anapc2 |
anaphase promoting complex subunit 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ANAPC2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
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|
G |
Anapc5 |
anaphase-promoting complex subunit 5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ANAPC5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:33,748,714...33,781,709
Ensembl chr12:33,748,735...33,781,781
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|
G |
Aox1 |
aldehyde oxidase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of AOX1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
|
|
G |
Aph1b |
aph-1 homolog B, gamma secretase subunit |
increases expression |
ISO |
Phlorhizin results in increased expression of APH1B mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
|
|
G |
App |
amyloid beta precursor protein |
decreases expression |
ISO |
Phlorhizin results in decreased expression of APP mRNA |
CTD |
PMID:22538082 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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|
G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ATF3 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
increases expression |
ISO |
Phlorhizin results in increased expression of ATP2A2 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
|
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ATP5A1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp5f1c |
ATP synthase F1 subunit gamma |
increases expression |
ISO |
Phlorhizin results in increased expression of ATP5C1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
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G |
Auh |
AU RNA binding methylglutaconyl-CoA hydratase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of AUH mRNA |
CTD |
PMID:22538082 |
|
NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
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G |
B2m |
beta-2 microglobulin |
increases expression |
ISO |
Phlorhizin results in increased expression of B2M mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
[2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] |
CTD |
PMID:32408695 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of BAG1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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G |
Bckdhb |
branched chain keto acid dehydrogenase E1 subunit beta |
decreases expression |
ISO |
Phlorhizin results in decreased expression of BCKDHB mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
ISO |
[2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] |
CTD |
PMID:32408695 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Birc6 |
baculoviral IAP repeat-containing 6 |
increases expression |
ISO |
Phlorhizin results in increased expression of BIRC6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
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G |
Cat |
catalase |
increases expression |
ISO |
Phlorhizin results in increased expression of CAT mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA |
CTD |
PMID:32408695 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Cct7 |
chaperonin containing TCP1 subunit 7 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CCT7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
multiple interactions |
EXP |
Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] |
CTD |
PMID:18715473 |
|
NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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G |
Clybl |
citramalyl-CoA lyase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CLYBL mRNA |
CTD |
PMID:22538082 |
|
NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
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G |
Cox15 |
cytochrome c oxidase assembly homolog COX15 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of COX15 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
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G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of COX17 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr11:62,400,733...62,406,507
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G |
Cox7c |
cytochrome c oxidase subunit 7C |
increases expression |
ISO |
Phlorhizin results in increased expression of COX7C mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
decreases expression |
ISO |
Phlorhizin results in decreased expression of COX8A mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:204,402,118...204,404,439
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|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CPT1A mRNA |
CTD |
PMID:16123366 PMID:22538082 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CPT2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crebbp |
CREB binding protein |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CREBBP mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Cs |
citrate synthase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CS mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Cul1 |
cullin 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CUL1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
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G |
Cyb5r3 |
cytochrome b5 reductase 3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CYB5R3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CYP2B6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
increases expression |
ISO |
Phlorhizin results in increased expression of CYP2D6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
decreases expression increases expression |
ISO |
Phlorhizin results in decreased expression of CYP3A7 mRNA Phlorhizin results in increased expression of CYP3A7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of CYP4F12 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
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G |
Dhrs4 |
dehydrogenase/reductase 4 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DHRS4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
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G |
Dld |
dihydrolipoamide dehydrogenase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DLD mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dnaja2 |
DnaJ heat shock protein family (Hsp40) member A2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJA2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
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G |
Dnaja3 |
DnaJ heat shock protein family (Hsp40) member A3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJA3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
decreases expression increases expression |
ISO |
Phlorhizin results in decreased expression of DNAJB1 mRNA Phlorhizin results in increased expression of DNAJB1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJB4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression |
ISO |
Phlorhizin results in increased expression of DNAJB6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
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G |
Dnajc1 |
DnaJ heat shock protein family (Hsp40) member C1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJC1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
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G |
Dnajc13 |
DnaJ heat shock protein family (Hsp40) member C13 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJC13 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:104,767,785...104,877,317
Ensembl chr 8:104,767,788...104,877,317
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G |
Dnajc14 |
DnaJ heat shock protein family (Hsp40) member C14 |
increases expression |
ISO |
Phlorhizin results in increased expression of DNAJC14 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:1,233,856...1,247,349
Ensembl chr 7:1,235,162...1,248,645
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G |
Dnajc19 |
DnaJ heat shock protein family (Hsp40) member C19 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJC19 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
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G |
Dnajc4 |
DnaJ heat shock protein family (Hsp40) member C4 |
increases expression |
ISO |
Phlorhizin results in increased expression of DNAJC4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
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G |
Dnajc5 |
DnaJ heat shock protein family (Hsp40) member C5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of DNAJC5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ECHS1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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G |
Ep300 |
E1A binding protein p300 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of EP300 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of EPHX1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
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G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
Phlorhizin results in decreased expression of FAS mRNA |
CTD |
PMID:16123366 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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|
G |
Fbxw7 |
F-box and WD repeat domain containing 7 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of FBXW7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
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G |
Fh |
fumarate hydratase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of FH mRNA |
CTD |
PMID:22538082 |
|
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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G |
Fis1 |
fission, mitochondrial 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of FIS1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of FKBP5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Fmo1 |
flavin containing dimethylaniline monoxygenase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of FMO1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
EXP |
Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] |
CTD |
PMID:12446591 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GCLC mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GCLM mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Glrx2 |
glutaredoxin 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GLRX2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
increases expression decreases expression |
ISO |
Phlorhizin results in increased expression of GPD2 mRNA Phlorhizin results in decreased expression of GPD2 mRNA |
CTD |
PMID:16123366 PMID:22538082 |
|
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
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G |
Gpx1 |
glutathione peroxidase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GPX1 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx7 |
glutathione peroxidase 7 |
increases expression |
ISO |
Phlorhizin results in increased expression of GPX7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GSTA5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstk1 |
glutathione S-transferase kappa 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GSTK1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
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G |
Gstm1 |
glutathione S-transferase mu 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of GSTM1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstm2 |
glutathione S-transferase mu 2 |
increases expression decreases expression |
ISO |
Phlorhizin results in increased expression of GSTM2 mRNA; Phlorhizin results in increased expression of GSTM5 mRNA Phlorhizin results in decreased expression of GSTM5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstm4 |
glutathione S-transferase mu 4 |
increases expression |
ISO |
Phlorhizin results in increased expression of GSTM4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of GSTP1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
decreases expression increases expression |
ISO |
Phlorhizin results in decreased expression of GSTT1 mRNA Phlorhizin results in increased expression of GSTT1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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|
G |
Hacd3 |
3-hydroxyacyl-CoA dehydratase 3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HACD3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
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|
G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression |
ISO |
Phlorhizin results in increased expression of HADHB mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hibadh |
3-hydroxyisobutyrate dehydrogenase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HIBADH mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
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|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HMGCS1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HMOX1 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hras |
HRas proto-oncogene, GTPase |
increases expression |
ISO |
Phlorhizin results in increased expression of HRAS mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
|
|
G |
Hsd17b10 |
hydroxysteroid (17-beta) dehydrogenase 10 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSD17B10 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr X:21,089,152...21,091,597
Ensembl chr X:21,089,122...21,109,488
|
|
G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSD17B4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
|
|
G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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|
G |
Hspa13 |
heat shock protein family A (Hsp70) member 13 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSPA13 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
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|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
Phlorhizin results in increased expression of HSPA5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases expression |
ISO |
Phlorhizin results in increased expression of HSPA8 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSPA9 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of HSPB1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
|
|
G |
Hspb8 |
heat shock protein family B (small) member 8 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSPB8 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSPD1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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|
G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HSPE1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
|
|
G |
Htra2 |
HtrA serine peptidase 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of HTRA2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
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|
G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of ID1 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
increases expression |
ISO |
Phlorhizin results in increased expression of IDH2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
|
|
G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
decreases expression |
ISO |
Phlorhizin results in decreased expression of IDH3A mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
|
|
G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
decreases expression |
ISO |
Phlorhizin results in decreased expression of IDH3B mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
|
|
G |
Idh3g |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma |
decreases expression |
ISO |
Phlorhizin results in decreased expression of IDH3G mRNA |
CTD |
PMID:22538082 |
|
NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL1B mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Ivd |
isovaleryl-CoA dehydrogenase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of IVD mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
Phlorhizin results in decreased expression of JUNB mRNA |
CTD |
PMID:22538082 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
|
|
G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Phlorhizin results in increased expression of JUND mRNA |
CTD |
PMID:22538082 |
|
NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
|
|
G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
increases expression |
ISO |
Phlorhizin results in increased expression of KCNJ11 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of KEAP1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
|
|
G |
Kras |
KRAS proto-oncogene, GTPase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of KRAS mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:178,185,418...178,218,484
|
|
G |
Lep |
leptin |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA]; [2,2-bis(4-glycidyloxyphenyl)propane co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of LEP mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
|
|
G |
Maf |
MAF bZIP transcription factor |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MAF mRNA |
CTD |
PMID:22538082 |
|
NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
|
|
G |
Mafg |
MAF bZIP transcription factor G |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MAFG mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
|
|
G |
Maob |
monoamine oxidase B |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MAOB mRNA |
CTD |
PMID:22538082 |
|
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
increases expression |
ISO |
Phlorhizin results in increased expression of MAP2K2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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|
G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
increases expression |
ISO |
Phlorhizin results in increased expression of MAP2K6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
|
|
G |
Map2k7 |
mitogen activated protein kinase kinase 7 |
increases expression |
ISO |
Phlorhizin results in increased expression of MAP2K7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
|
|
G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MAP3K7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression |
ISO |
Phlorhizin results in increased expression of MAPK3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MAPK9 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
|
|
G |
Mccc2 |
methylcrotonyl-CoA carboxylase subunit 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MCCC2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MDM2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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|
G |
Med20 |
mediator complex subunit 20 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MED20 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:13,370,146...13,382,756
Ensembl chr 9:13,370,146...13,382,476
|
|
G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of MGST1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
|
|
G |
Mmut |
methylmalonyl-CoA mutase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of MMUT mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
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|
G |
Myl9 |
myosin light chain 9 |
decreases phosphorylation |
EXP |
Phlorhizin results in decreased phosphorylation of MYL9 protein |
CTD |
PMID:17272349 |
|
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
|
|
G |
Ndufa12 |
NADH:ubiquinone oxidoreductase subunit A12 |
increases expression |
ISO |
Phlorhizin results in increased expression of NDUFA12 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315
|
|
G |
Ndufa2 |
NADH:ubiquinone oxidoreductase subunit A2 |
increases expression |
ISO |
Phlorhizin results in increased expression of NDUFA2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
|
|
G |
Ndufa3 |
NADH:ubiquinone oxidoreductase subunit A3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFA3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:65,597,562...65,600,242
Ensembl chr 1:65,597,578...65,600,235
|
|
G |
Ndufa7 |
NADH:ubiquinone oxidoreductase subunit A7 |
increases expression |
ISO |
Phlorhizin results in increased expression of NDUFA7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976
|
|
G |
Ndufab1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression |
ISO |
Phlorhizin results in increased expression of NDUFAB1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
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|
G |
Ndufaf1 |
NADH:ubiquinone oxidoreductase complex assembly factor 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFAF1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212
|
|
G |
Ndufb6 |
NADH:ubiquinone oxidoreductase subunit B6 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFB6 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181
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|
G |
Ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFS1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
|
|
G |
Ndufs4 |
NADH:ubiquinone oxidoreductase subunit S4 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFS4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
|
|
G |
Ndufs5 |
NADH:ubiquinone oxidoreductase subunit S5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NDUFS5 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
|
|
G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
increases expression |
ISO |
Phlorhizin results in increased expression of NDUFS8 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
|
|
G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NEDD4 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
|
|
G |
Neurod1 |
neuronal differentiation 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of NEUROD1 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NFE2L2 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
[Phlorhizin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane co-treated with cobaltous chloride] affects the expression of NFKB1 mRNA |
CTD |
PMID:32408695 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
|
|
G |
Nkx6-1 |
NK6 homeobox 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of NKX6-1 mRNA |
CTD |
PMID:16123366 |
|
NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681
|
|
G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions decreases expression |
ISO |
Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA] Phlorhizin results in decreased expression of NOS3 mRNA |
CTD |
PMID:20021702 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
|
|
G |
Nras |
NRAS proto-oncogene, GTPase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of NRAS mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
|
|
G |
Ogdh |
oxoglutarate dehydrogenase |
decreases expression |
ISO |
Phlorhizin results in decreased expression of OGDH mRNA |
CTD |
PMID:22538082 |
|
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
|
|
G |
Park7 |
Parkinsonism associated deglycase |
increases expression |
ISO |
Phlorhizin results in increased expression of PARK7 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
|
|
G |
Pc |
pyruvate carboxylase |
increases expression decreases expression |
ISO |
Phlorhizin results in increased expression of PCX mRNA Phlorhizin results in decreased expression of PC mRNA |
CTD |
PMID:16123366 PMID:22538082 |
|
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
|
|
G |
Pcca |
propionyl-CoA carboxylase subunit alpha |
decreases expression |
ISO |
Phlorhizin results in decreased expression of PCCA mRNA |
CTD |
PMID:22538082 |
|
NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
|
|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of PCK1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
|
|
G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
increases expression decreases expression |
ISO |
Phlorhizin results in increased expression of PECR mRNA Phlorhizin results in decreased expression of PECR mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
|
|
G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
decreases expression |
ISO |
Phlorhizin results in decreased expression of PIK3C2A mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
|
|
G |
Pik3c3 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of PIK3C3 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
|
|
G |
Pink1 |
PTEN induced kinase 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of PINK1 mRNA |
CTD |
PMID:22538082 |
|
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Prdx1 |
peroxiredoxin 1 |
increases expression |
ISO |
Phlorhizin results in increased expression of PRDX1 mRNA |
CTD |
PMID:22538082 |
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NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
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G |
Prdx5 |
peroxiredoxin 5 |
decreases expression |
ISO |
Phlorhizin results in decreased expression of PRDX5 mRNA |
CTD |
PMID:22538082 |
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NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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G |
Prkch |
protein kinase C, eta |
increases expression |
ISO |
Phlorhizin results in incre | |