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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phlorizin
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Accession:CHEBI:8113 term browser browse the term
Definition:An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2' via a glycosidic linkage.
Synonyms:exact_synonym: 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside
 related_synonym: Floridzin;   Formula=C21H24O10;   InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1;   InChIKey=IOUVKUPGCMBWBT-QNDFHXLGSA-N;   Phloretin 2'-glucoside;   Phlorhizin;   Phloridzin;   Phlorizoside;   SMILES=OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
 xref: Beilstein:66621;   CAS:60-81-1;   HMDB:HMDB0036634;   KEGG:C01604;   KNApSAcK:C00000990;   LINCS:LSM-25654
 xref_mesh: MESH:D010695
 xref: MetaCyc:CPD-12447;   PMID:18573104;   PMID:24392851;   Patent:CN102697895;   Patent:CN103214530;   Reaxys:66621;   Wikipedia:Phlorizin



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phlorizin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase decreases expression ISO Phlorhizin results in decreased expression of ABAT mRNA CTD PMID:22538082 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Phlorhizin results in increased expression of ACAA1 mRNA CTD PMID:22538082 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of ACAA2 mRNA CTD PMID:22538082 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 decreases expression ISO Phlorhizin results in decreased expression of ACAD8 mRNA CTD PMID:22538082 NCBI chr 8:25,382,271...25,406,429
Ensembl chr 8:25,382,273...25,406,414
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression ISO Phlorhizin results in decreased expression of ACAD9 mRNA CTD PMID:22538082 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO Phlorhizin results in decreased expression of ACADL mRNA CTD PMID:22538082 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO Phlorhizin results in decreased expression of ACAT1 mRNA CTD PMID:22538082 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Aco1 aconitase 1 decreases expression ISO Phlorhizin results in decreased expression of ACO1 mRNA CTD PMID:22538082 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of ACOX1 mRNA CTD PMID:22538082 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Phlorhizin results in decreased expression of ACOX2 mRNA CTD PMID:22538082 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Phlorhizin results in decreased expression of ACSL1 mRNA CTD PMID:22538082 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Actb actin, beta increases expression ISO Phlorhizin results in increased expression of ACTB mRNA CTD PMID:22538082 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression ISO Phlorhizin results in decreased expression of ADH5 mRNA CTD PMID:22538082 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression ISO Phlorhizin results in decreased expression of ADHFE1 mRNA CTD PMID:22538082 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 decreases expression ISO Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression ISO Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Alb albumin multiple interactions ISO Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] CTD PMID:16313995 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression
increases expression
ISO Phlorhizin results in decreased expression of ALDH2 mRNA
Phlorhizin results in increased expression of ALDH2 mRNA
CTD PMID:22538082 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Phlorhizin results in decreased expression of ALDH3A2 mRNA CTD PMID:22538082 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH4A1 mRNA CTD PMID:22538082 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH6A1 mRNA CTD PMID:22538082 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH7A1 mRNA CTD PMID:22538082 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 decreases expression ISO Phlorhizin results in decreased expression of ANAPC2 mRNA CTD PMID:22538082 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 decreases expression ISO Phlorhizin results in decreased expression of ANAPC5 mRNA CTD PMID:22538082 NCBI chr12:33,748,714...33,781,709
Ensembl chr12:33,748,735...33,781,781
JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of AOX1 mRNA CTD PMID:22538082 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit increases expression ISO Phlorhizin results in increased expression of APH1B mRNA CTD PMID:22538082 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G App amyloid beta precursor protein decreases expression ISO Phlorhizin results in decreased expression of APP mRNA CTD PMID:22538082 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Phlorhizin results in decreased expression of ATF3 mRNA CTD PMID:16123366 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO Phlorhizin results in increased expression of ATP2A2 mRNA CTD PMID:16123366 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression ISO Phlorhizin results in decreased expression of ATP5A1 mRNA CTD PMID:22538082 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma increases expression ISO Phlorhizin results in increased expression of ATP5C1 mRNA CTD PMID:22538082 NCBI chr17:68,423,927...68,446,169 JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase decreases expression ISO Phlorhizin results in decreased expression of AUH mRNA CTD PMID:22538082 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Phlorhizin results in increased expression of B2M mRNA CTD PMID:22538082 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Phlorhizin results in decreased expression of BAG1 mRNA CTD PMID:22538082 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Phlorhizin results in decreased expression of BCKDHB mRNA CTD PMID:22538082 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression ISO Phlorhizin results in increased expression of BIRC6 mRNA CTD PMID:22538082 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Cat catalase increases expression ISO Phlorhizin results in increased expression of CAT mRNA CTD PMID:22538082 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Phlorhizin results in decreased expression of CCT7 mRNA CTD PMID:22538082 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions EXP Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] CTD PMID:18715473 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Clybl citramalyl-CoA lyase decreases expression ISO Phlorhizin results in decreased expression of CLYBL mRNA CTD PMID:22538082 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 decreases expression ISO Phlorhizin results in decreased expression of COX15 mRNA CTD PMID:22538082 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Phlorhizin results in decreased expression of COX17 mRNA CTD PMID:22538082 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox7c cytochrome c oxidase subunit 7C increases expression ISO Phlorhizin results in increased expression of COX7C mRNA CTD PMID:22538082 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression ISO Phlorhizin results in decreased expression of COX8A mRNA CTD PMID:22538082 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO Phlorhizin results in decreased expression of CPT1A mRNA CTD PMID:16123366 PMID:22538082 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of CPT2 mRNA CTD PMID:22538082 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crebbp CREB binding protein decreases expression ISO Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Cs citrate synthase decreases expression ISO Phlorhizin results in decreased expression of CS mRNA CTD PMID:22538082 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cul1 cullin 1 decreases expression ISO Phlorhizin results in decreased expression of CUL1 mRNA CTD PMID:22538082 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression ISO Phlorhizin results in decreased expression of CYB5R3 mRNA CTD PMID:22538082 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression ISO Phlorhizin results in decreased expression of CYP1A2 mRNA CTD PMID:22538082 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO Phlorhizin results in decreased expression of CYP2B6 mRNA CTD PMID:22538082 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression ISO Phlorhizin results in increased expression of CYP2D6 mRNA CTD PMID:22538082 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of CYP3A7 mRNA
Phlorhizin results in increased expression of CYP3A7 mRNA
CTD PMID:22538082 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression ISO Phlorhizin results in increased expression of CYP4A11 mRNA CTD PMID:22538082 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO Phlorhizin results in decreased expression of CYP4F12 mRNA CTD PMID:22538082 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 decreases expression ISO Phlorhizin results in decreased expression of DHRS4 mRNA CTD PMID:22538082 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of DLD mRNA CTD PMID:22538082 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression ISO Phlorhizin results in decreased expression of DNAJA2 mRNA CTD PMID:22538082 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Phlorhizin results in decreased expression of DNAJA3 mRNA CTD PMID:22538082 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of DNAJB1 mRNA
Phlorhizin results in increased expression of DNAJB1 mRNA
CTD PMID:22538082 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression ISO Phlorhizin results in decreased expression of DNAJB4 mRNA CTD PMID:22538082 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Phlorhizin results in increased expression of DNAJB6 mRNA CTD PMID:22538082 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression ISO Phlorhizin results in decreased expression of DNAJC1 mRNA CTD PMID:22538082 NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression ISO Phlorhizin results in decreased expression of DNAJC13 mRNA CTD PMID:22538082 NCBI chr 8:104,767,785...104,877,317
Ensembl chr 8:104,767,788...104,877,317
JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 increases expression ISO Phlorhizin results in increased expression of DNAJC14 mRNA CTD PMID:22538082 NCBI chr 7:1,233,856...1,247,349
Ensembl chr 7:1,235,162...1,248,645
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Phlorhizin results in decreased expression of DNAJC19 mRNA CTD PMID:22538082 NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Phlorhizin results in decreased expression of DNAJC3 mRNA CTD PMID:22538082 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 increases expression ISO Phlorhizin results in increased expression of DNAJC4 mRNA CTD PMID:22538082 NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression ISO Phlorhizin results in decreased expression of DNAJC5 mRNA CTD PMID:22538082 NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Phlorhizin results in decreased expression of ECHS1 mRNA CTD PMID:22538082 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO Phlorhizin results in decreased expression of EP300 mRNA CTD PMID:22538082 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Phlorhizin results in decreased expression of FAS mRNA CTD PMID:16123366 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 decreases expression ISO Phlorhizin results in decreased expression of FBXW7 mRNA CTD PMID:22538082 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fh fumarate hydratase decreases expression ISO Phlorhizin results in decreased expression of FH mRNA CTD PMID:22538082 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Phlorhizin results in increased expression of FIS1 mRNA CTD PMID:22538082 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO Phlorhizin results in decreased expression of FKBP5 mRNA CTD PMID:22538082 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of FMO1 mRNA CTD PMID:22538082 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] CTD PMID:12446591 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Phlorhizin results in decreased expression of GCLC mRNA CTD PMID:22538082 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Glrx2 glutaredoxin 2 decreases expression ISO Phlorhizin results in decreased expression of GLRX2 mRNA CTD PMID:22538082 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression
decreases expression
ISO Phlorhizin results in increased expression of GPD2 mRNA
Phlorhizin results in decreased expression of GPD2 mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO Phlorhizin results in decreased expression of GPX1 mRNA CTD PMID:16123366 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression ISO Phlorhizin results in increased expression of GPX7 mRNA CTD PMID:22538082 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases expression ISO Phlorhizin results in decreased expression of GSTA5 mRNA CTD PMID:22538082 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO Phlorhizin results in decreased expression of GSTK1 mRNA CTD PMID:22538082 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression ISO Phlorhizin results in decreased expression of GSTM1 mRNA CTD PMID:22538082 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO Phlorhizin results in increased expression of GSTM2 mRNA CTD PMID:22538082 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO Phlorhizin results in increased expression of GSTM4 mRNA CTD PMID:22538082 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of GSTM5 mRNA
Phlorhizin results in increased expression of GSTM5 mRNA
CTD PMID:22538082 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO Phlorhizin results in increased expression of GSTP1 mRNA CTD PMID:22538082 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of GSTT1 mRNA
Phlorhizin results in increased expression of GSTT1 mRNA
CTD PMID:22538082 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression ISO Phlorhizin results in decreased expression of GSTT2B mRNA CTD PMID:22538082 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression ISO Phlorhizin results in decreased expression of HACD3 mRNA CTD PMID:22538082 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Phlorhizin results in increased expression of HADHB mRNA CTD PMID:22538082 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Phlorhizin results in decreased expression of HERPUD1 mRNA CTD PMID:22538082 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of HIBADH mRNA CTD PMID:22538082 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Phlorhizin results in decreased expression of HMGCS1 mRNA CTD PMID:22538082 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of HMOX1 mRNA CTD PMID:16123366 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Phlorhizin results in increased expression of HRAS mRNA CTD PMID:22538082 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Phlorhizin results in decreased expression of HSD17B10 mRNA CTD PMID:22538082 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO Phlorhizin results in decreased expression of HSD17B4 mRNA CTD PMID:22538082 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AA1 mRNA CTD PMID:22538082 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AB1 mRNA CTD PMID:22538082 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Phlorhizin results in decreased expression of HSPA13 mRNA CTD PMID:22538082 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Phlorhizin results in decreased expression of HSPA9 mRNA CTD PMID:22538082 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Phlorhizin results in increased expression of HSPB1 mRNA CTD PMID:22538082 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 decreases expression ISO Phlorhizin results in decreased expression of HSPB8 mRNA CTD PMID:22538082 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPD1 mRNA CTD PMID:22538082 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPE1 mRNA CTD PMID:22538082 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression ISO Phlorhizin results in decreased expression of HTRA2 mRNA CTD PMID:22538082 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Phlorhizin results in decreased expression of ID1 mRNA CTD PMID:16123366 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Phlorhizin results in increased expression of IDH2 mRNA CTD PMID:22538082 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO Phlorhizin results in decreased expression of IDH3A mRNA CTD PMID:22538082 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta decreases expression ISO Phlorhizin results in decreased expression of IDH3B mRNA CTD PMID:22538082 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma decreases expression ISO Phlorhizin results in decreased expression of IDH3G mRNA CTD PMID:22538082 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of IVD mRNA CTD PMID:22538082 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Phlorhizin results in decreased expression of JUNB mRNA CTD PMID:22538082 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Phlorhizin results in increased expression of JUND mRNA CTD PMID:22538082 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 increases expression ISO Phlorhizin results in increased expression of KCNJ11 mRNA CTD PMID:16123366 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of KRAS mRNA CTD PMID:22538082 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO Phlorhizin results in decreased expression of MAF mRNA CTD PMID:22538082 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Mafg MAF bZIP transcription factor G decreases expression ISO Phlorhizin results in decreased expression of MAFG mRNA CTD PMID:22538082 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Maob monoamine oxidase B decreases expression ISO Phlorhizin results in decreased expression of MAOB mRNA CTD PMID:22538082 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases expression ISO Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression ISO Phlorhizin results in increased expression of MAP2K6 mRNA CTD PMID:22538082 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 increases expression ISO Phlorhizin results in increased expression of MAP2K7 mRNA CTD PMID:22538082 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases expression ISO Phlorhizin results in decreased expression of MAP3K7 mRNA CTD PMID:22538082 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO Phlorhizin results in increased expression of MAPK3 mRNA CTD PMID:22538082 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression ISO Phlorhizin results in decreased expression of MAPK9 mRNA CTD PMID:22538082 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Phlorhizin results in decreased expression of MCCC2 mRNA CTD PMID:22538082 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Med20 mediator complex subunit 20 decreases expression ISO Phlorhizin results in decreased expression of MED20 mRNA CTD PMID:22538082 NCBI chr 9:13,370,146...13,382,756
Ensembl chr 9:13,370,146...13,382,476
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Phlorhizin results in increased expression of MGST1 mRNA CTD PMID:22538082 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mmut methylmalonyl-CoA mutase decreases expression ISO Phlorhizin results in decreased expression of MMUT mRNA CTD PMID:22538082 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Myl9 myosin light chain 9 decreases phosphorylation EXP Phlorhizin results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 increases expression ISO Phlorhizin results in increased expression of NDUFA12 mRNA CTD PMID:22538082 NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 increases expression ISO Phlorhizin results in increased expression of NDUFA2 mRNA CTD PMID:22538082 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Phlorhizin results in decreased expression of NDUFA3 mRNA CTD PMID:22538082 NCBI chr 1:65,597,562...65,600,242
Ensembl chr 1:65,597,578...65,600,235
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression ISO Phlorhizin results in increased expression of NDUFA7 mRNA CTD PMID:22538082 NCBI chr 7:14,609,283...14,622,064 JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Phlorhizin results in increased expression of NDUFAB1 mRNA CTD PMID:22538082 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Phlorhizin results in decreased expression of NDUFAF1 mRNA CTD PMID:22538082 NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO Phlorhizin results in decreased expression of NDUFB6 mRNA CTD PMID:22538082 NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Phlorhizin results in decreased expression of NDUFS1 mRNA CTD PMID:22538082 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO Phlorhizin results in decreased expression of NDUFS4 mRNA CTD PMID:22538082 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 decreases expression ISO Phlorhizin results in decreased expression of NDUFS5 mRNA CTD PMID:22538082 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression ISO Phlorhizin results in increased expression of NDUFS8 mRNA CTD PMID:22538082 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Phlorhizin results in decreased expression of NEDD4 mRNA CTD PMID:22538082 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Neurod1 neuronal differentiation 1 increases expression ISO Phlorhizin results in increased expression of NEUROD1 mRNA CTD PMID:16123366 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO Phlorhizin results in decreased expression of NFE2L2 mRNA CTD PMID:22538082 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nkx6-1 NK6 homeobox 1 increases expression ISO Phlorhizin results in increased expression of NKX6-1 mRNA CTD PMID:16123366 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
ISO Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
Phlorhizin results in decreased expression of NOS3 mRNA
CTD PMID:20021702 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of NRAS mRNA CTD PMID:22538082 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of OGDH mRNA CTD PMID:22538082 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Phlorhizin results in increased expression of PARK7 mRNA CTD PMID:22538082 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pc pyruvate carboxylase increases expression
decreases expression
ISO Phlorhizin results in increased expression of PCX mRNA
Phlorhizin results in decreased expression of PC mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha decreases expression ISO Phlorhizin results in decreased expression of PCCA mRNA CTD PMID:22538082 NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Phlorhizin results in decreased expression of PCK1 mRNA CTD PMID:22538082 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase increases expression
decreases expression
ISO Phlorhizin results in increased expression of PECR mRNA
Phlorhizin results in decreased expression of PECR mRNA
CTD PMID:22538082 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression ISO Phlorhizin results in decreased expression of PIK3C2A mRNA CTD PMID:22538082 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO Phlorhizin results in decreased expression of PIK3C3 mRNA CTD PMID:22538082 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pink1 PTEN induced kinase 1 increases expression ISO Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO Phlorhizin results in increased expression of PRDX1 mRNA CTD PMID:22538082 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO Phlorhizin results in decreased expression of PRDX5 mRNA CTD PMID:22538082 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prkch protein kinase C, eta increases expression ISO Phlorhizin results in increased expression of PRKCH mRNA CTD PMID:22538082 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkci protein kinase C, iota decreases expression ISO Phlorhizin results in decreased expression of PRKCI mRNA CTD PMID:22538082 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Prkd3 protein kinase D3 decreases expression ISO Phlorhizin results in decreased expression of PRKD3 mRNA CTD PMID:22538082 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 decreases expression ISO Phlorhizin results in decreased expression of PSMA4 mRNA CTD PMID:22538082 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression ISO Phlorhizin results in increased expression of PSMB1 mRNA CTD PMID:22538082 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 decreases expression ISO Phlorhizin results in decreased expression of PSMB2 mRNA CTD PMID:22538082 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 decreases expression ISO Phlorhizin results in decreased expression of PSMC1 mRNA CTD PMID:22538082 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression
decreases expression
ISO Phlorhizin results in increased expression of PSMC4 mRNA
Phlorhizin results in decreased expression of PSMC4 mRNA
CTD PMID:22538082 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 decreases expression ISO Phlorhizin results in decreased expression of PSMC6 mRNA CTD PMID:22538082 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 decreases expression ISO Phlorhizin results in decreased expression of PSMD10 mRNA CTD PMID:22538082 NCBI chr  X:104,656,809...104,665,126 JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 decreases expression ISO Phlorhizin results in decreased expression of PSMD12 mRNA CTD PMID:22538082 NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 decreases expression ISO Phlorhizin results in decreased expression of PSMD14 mRNA CTD PMID:22538082 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 decreases expression ISO Phlorhizin results in decreased expression of PSMD4 mRNA CTD PMID:22538082 NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 increases expression ISO Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 NCBI chr15:11,102,208...11,112,180
Ensembl chr15:11,102,180...11,205,620
JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 decreases expression ISO Phlorhizin results in decreased expression of PSMD7 mRNA CTD PMID:22538082 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 decreases expression ISO Phlorhizin results in decreased expression of PSMD9 mRNA CTD PMID:22538082 NCBI chr12:33,337,182...33,357,468 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rdh14 retinol dehydrogenase 14 increases expression ISO Phlorhizin results in increased expression of RDH14 mRNA CTD PMID:22538082 NCBI chr 6:33,156,569...33,161,712
Ensembl chr 6:33,156,569...33,161,712
JBrowse link
G S100a6 S100 calcium binding protein A6 decreases expression ISO Phlorhizin results in decreased expression of S100A6 mRNA CTD PMID:16123366 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A decreases expression ISO Phlorhizin results in decreased expression of SDHA mRNA CTD PMID:22538082 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B increases expression ISO Phlorhizin results in increased expression of SDHB mRNA CTD PMID:22538082 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sds serine dehydratase decreases expression ISO Phlorhizin results in decreased expression of SDS mRNA CTD PMID:22538082 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO Phlorhizin results in increased expression of SLC2A2 mRNA CTD PMID:16123366 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc35a2 solute carrier family 35 member A2 increases expression ISO Phlorhizin results in increased expression of SLC35A2 mRNA CTD PMID:22538082 NCBI chr  X:14,608,145...14,616,937
Ensembl chr  X:14,608,055...14,616,678
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions
decreases activity
affects binding
ISO
EXP
Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside]; Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose
SLC5A1 protein binds to Phlorhizin
CTD PMID:12663055 PMID:12927799 PMID:16300400 PMID:17288452 PMID:17983207 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Slc5a2 solute carrier family 5 member 2 decreases activity ISO Phlorhizin results in decreased activity of SLC5A2 protein CTD PMID:21128592 NCBI chr 1:182,847,185...182,853,309
Ensembl chr 1:182,847,106...182,853,306
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO Phlorhizin results in increased expression of SOD1 mRNA CTD PMID:22538082 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Phlorhizin results in decreased expression of SOD2 mRNA CTD PMID:22538082 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Phlorhizin results in decreased expression of STIP1 mRNA CTD PMID:22538082 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLA2 mRNA CTD PMID:22538082 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLG2 mRNA CTD PMID:22538082 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
JBrowse link
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone decreases expression ISO Phlorhizin results in decreased expression of SUGT1 mRNA CTD PMID:22538082 NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
JBrowse link
G Txn1 thioredoxin 1 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of TXN mRNA
Phlorhizin results in increased expression of TXN mRNA
CTD PMID:22538082 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Phlorhizin results in increased expression of TXN2 mRNA CTD PMID:22538082 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Ubb ubiquitin B increases expression ISO Phlorhizin results in increased expression of UBB mRNA CTD PMID:22538082 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Ubc ubiquitin C decreases expression ISO Phlorhizin results in decreased expression of UBC mRNA CTD PMID:22538082 NCBI chr12:31,238,889...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B decreases expression ISO Phlorhizin results in decreased expression of UBE2B mRNA CTD PMID:22538082 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression ISO Phlorhizin results in decreased expression of UBE2F mRNA CTD PMID:22538082 NCBI chr 9:91,845,954...91,881,145
Ensembl chr 9:91,845,987...91,880,594
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H decreases expression ISO Phlorhizin results in decreased expression of UBE2H mRNA CTD PMID:22538082 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I decreases expression ISO Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 decreases expression ISO Phlorhizin results in decreased expression of UBE2L3 mRNA CTD PMID:22538082 NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862
JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M increases expression ISO Phlorhizin results in increased expression of UBE2M mRNA CTD PMID:22538082 NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO Phlorhizin results in decreased expression of UBE2N mRNA CTD PMID:22538082 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2q1 ubiquitin conjugating enzyme E2 Q1 increases expression ISO Phlorhizin results in increased expression of UBE2Q1 mRNA CTD PMID:22538082 NCBI chr 2:175,198,793...175,209,152
Ensembl chr 2:175,198,873...175,207,942
JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 decreases expression ISO Phlorhizin results in decreased expression of UBE2R2 mRNA CTD PMID:22538082 NCBI chr 5:56,286,604...56,345,160
Ensembl chr 5:56,286,725...56,345,513
JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 decreases expression ISO Phlorhizin results in decreased expression of UBE2V2 mRNA CTD PMID:22538082 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369
JBrowse link
G Ube4a ubiquitination factor E4A increases expression ISO Phlorhizin results in increased expression of UBE4A mRNA CTD PMID:22538082 NCBI chr 8:45,236,022...45,278,129
Ensembl chr 8:45,236,026...45,278,038
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Phlorhizin results in increased expression of UBR2 mRNA CTD PMID:22538082 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Phlorhizin results in decreased expression of UCHL3 mRNA CTD PMID:22538082 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 decreases expression ISO Phlorhizin results in decreased expression of UCHL5 mRNA CTD PMID:22538082 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression ISO Phlorhizin results in decreased expression of UQCRC2 mRNA CTD PMID:22538082 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
G Usp1 ubiquitin specific peptidase 1 increases expression ISO Phlorhizin results in increased expression of USP1 mRNA CTD PMID:22538082 NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
JBrowse link
G Usp14 ubiquitin specific peptidase 14 decreases expression ISO Phlorhizin results in decreased expression of USP14 mRNA CTD PMID:22538082 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression ISO Phlorhizin results in increased expression of USP19 mRNA CTD PMID:22538082 NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741
JBrowse link
G Usp24 ubiquitin specific peptidase 24 decreases expression ISO Phlorhizin results in decreased expression of USP24 mRNA CTD PMID:22538082 NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311
JBrowse link
G Usp33 ubiquitin specific peptidase 33 decreases expression ISO Phlorhizin results in decreased expression of USP33 mRNA CTD PMID:22538082 NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479
JBrowse link
G Usp4 ubiquitin specific peptidase 4 increases expression ISO Phlorhizin results in increased expression of USP4 mRNA CTD PMID:22538082 NCBI chr 8:109,035,402...109,080,427
Ensembl chr 8:109,036,099...109,080,427
JBrowse link
G Usp45 ubiquitin specific peptidase 45 decreases expression ISO Phlorhizin results in decreased expression of USP45 mRNA CTD PMID:22538082 NCBI chr 5:35,318,621...35,392,090
Ensembl chr 5:35,318,635...35,389,420
JBrowse link
G Usp46 ubiquitin specific peptidase 46 decreases expression ISO Phlorhizin results in decreased expression of USP46 mRNA CTD PMID:22538082 NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
JBrowse link
G Usp7 ubiquitin specific peptidase 7 decreases expression ISO Phlorhizin results in decreased expression of USP7 mRNA CTD PMID:22538082 NCBI chr10:6,880,684...6,925,033
Ensembl chr10:6,828,795...6,925,355
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked decreases expression ISO Phlorhizin results in decreased expression of USP9X mRNA CTD PMID:22538082 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Phlorhizin results in decreased expression of XIAP mRNA CTD PMID:22538082 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      chemical role 19316
        antioxidant 14437
          phlorizin 232
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            heteroorganic entity 19273
                              organochalcogen compound 19047
                                organooxygen compound 18993
                                  carbohydrates and carbohydrate derivatives 12344
                                    carbohydrate 12344
                                      monosaccharide 4305
                                        aldose 2691
                                          aldohexose 2330
                                            glucose 2294
                                              D-glucose 2294
                                                D-glucopyranose 1761
                                                  beta-D-glucose 1626
                                                    beta-D-glucoside 1431
                                                      aryl beta-D-glucoside 251
                                                        phlorizin 232
paths to the root