Aldh7a1 (aldehyde dehydrogenase family 7, member A1) - Rat Genome Database

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Gene: Aldh7a1 (aldehyde dehydrogenase family 7, member A1) Mus musculus
Analyze
Symbol: Aldh7a1
Name: aldehyde dehydrogenase family 7, member A1
RGD ID: 1318490
MGI Page MGI
Description: Predicted to enable betaine-aldehyde dehydrogenase activity and identical protein binding activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; metanephros; nervous system; respiratory system; and sensory organ. Used to study pyridoxine-dependent epilepsy. Human ortholog(s) of this gene implicated in early-onset vitamin B6-dependent epilepsy 4. Orthologous to human ALDH7A1 (aldehyde dehydrogenase 7 family member A1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: aldehyde dehydrogenase 7 family, member A1; aldehyde dehydrogenase family 7 member A1; alpha-AASA dehydrogenase; alpha-aminoadipic semialdehyde dehydrogenase; antiquitin-1; Atq; Atq1; betaine aldehyde dehydrogenase; D18Wsu181; D18Wsu181e; delta1-piperideine-6-carboxylate dehydrogenase; delta1-piperideine-6-carboxylate dehydrogenease; P6c dehydrogenase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391856,657,794 - 56,706,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1856,642,759 - 56,706,023 (-)EnsemblGRCm39 Ensembl
GRCm381856,524,722 - 56,572,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1856,509,687 - 56,572,951 (-)EnsemblGRCm38mm10GRCm38
MGSCv371856,685,390 - 56,732,593 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361856,651,105 - 56,698,241 (-)NCBIMGSCv36mm8
Celera1857,828,935 - 57,877,977 (-)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1830.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allysine  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP)
Benzo[ghi]perylene  (EXP)
biochanin A  (ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
butylated hydroxyanisole  (EXP)
cadmium dichloride  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dihydroartemisinin  (ISO)
dioscin  (EXP,ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
fipronil  (ISO)
flurbiprofen  (EXP)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
furan  (ISO)
gentamycin  (ISO)
glyphosate  (EXP)
hexanal  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (EXP)
isobutanol  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP)
methidathion  (EXP)
methimazole  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosomorpholine  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
phlorizin  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (EXP)
propiconazole  (ISO)
Propiverine  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
mitochondrion  (HDA,ISO)
nucleus  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. Cao Y, etal., J Proteome Res. 2019 May 3;18(5):2032-2044. doi: 10.1021/acs.jproteome.8b00921. Epub 2019 Mar 29.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8464915   PMID:8889548   PMID:9158147   PMID:9299440   PMID:9417906   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273  
PMID:14681479   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17010133   PMID:18614015   PMID:18799693   PMID:18971422   PMID:20207735   PMID:21267068  
PMID:21873635   PMID:28245920   PMID:32325033   PMID:32969477   PMID:33537098   PMID:33601422   PMID:34702858  


Genomics

Comparative Map Data
Aldh7a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391856,657,794 - 56,706,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1856,642,759 - 56,706,023 (-)EnsemblGRCm39 Ensembl
GRCm381856,524,722 - 56,572,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1856,509,687 - 56,572,951 (-)EnsemblGRCm38mm10GRCm38
MGSCv371856,685,390 - 56,732,593 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361856,651,105 - 56,698,241 (-)NCBIMGSCv36mm8
Celera1857,828,935 - 57,877,977 (-)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1830.55NCBI
ALDH7A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385126,541,841 - 126,595,219 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5126,531,200 - 126,595,362 (-)EnsemblGRCh38hg38GRCh38
GRCh375125,877,533 - 125,930,911 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365125,908,344 - 125,958,839 (-)NCBINCBI36Build 36hg18NCBI36
Build 345125,908,347 - 125,958,756NCBI
Cytogenetic Map5q23.2NCBI
HuRef5121,068,235 - 121,122,325 (-)NCBIHuRef
CHM1_15125,309,919 - 125,363,679 (-)NCBICHM1_1
T2T-CHM13v2.05127,058,709 - 127,112,081 (-)NCBIT2T-CHM13v2.0
Aldh7a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,208,035 - 52,240,293 (-)NCBIGRCr8
mRatBN7.21850,003,242 - 50,042,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1850,009,934 - 50,042,193 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1852,048,134 - 52,080,362 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01852,756,122 - 52,788,453 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01850,554,002 - 50,586,230 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01851,619,007 - 51,651,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1851,619,007 - 51,651,267 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01850,814,203 - 50,846,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,300,899 - 52,333,149 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11852,346,394 - 52,378,655 (-)NCBI
Celera1848,155,257 - 48,187,477 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Aldh7a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555214,364,638 - 4,396,129 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555214,365,075 - 4,396,105 (-)NCBIChiLan1.0ChiLan1.0
ALDH7A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24121,858,390 - 121,910,911 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15119,996,435 - 120,050,338 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05121,946,527 - 122,000,273 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15127,718,978 - 127,771,047 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5127,718,978 - 127,771,047 (-)Ensemblpanpan1.1panPan2
ALDH7A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11115,828,581 - 15,878,556 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1115,815,936 - 15,878,516 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,623,590 - 14,671,820 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,555,891 - 16,604,274 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,489,913 - 16,604,251 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11115,287,402 - 15,335,601 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01115,133,391 - 15,181,763 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,729,874 - 15,778,117 (-)NCBIUU_Cfam_GSD_1.0
Aldh7a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213138,385,899 - 138,424,789 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365756,467,340 - 6,506,006 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365756,467,224 - 6,506,052 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH7A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2129,662,969 - 129,709,705 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12129,663,226 - 129,709,728 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22134,953,156 - 134,988,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH7A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12329,539,897 - 29,589,004 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603448,486,643 - 48,538,244 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh7a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477415,048,627 - 15,101,856 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477415,048,825 - 15,099,443 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aldh7a1
2331 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3284
Count of miRNA genes:890
Interacting mature miRNAs:1239
Transcripts:ENSMUST00000066208, ENSMUST00000168517, ENSMUST00000170309, ENSMUST00000171844, ENSMUST00000171851, ENSMUST00000172734, ENSMUST00000172902, ENSMUST00000174518, ENSMUST00000174704
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182411556058115730Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse
12904950Smmq3_msoleus muscle mass QTL 3 (mouse)182605687560056875Mouse
25823167Hrsq5_mhost response to SARS QTL 5, D3% weight (mouse)182724111558827077Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182724111558827077Mouse
25823174Hrsq11_mhost response to SARS QTL 11, log titer (mouse)182724111558827077Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2813060462130739Mouse
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183023306764233067Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183198848065988629Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183309104367091221Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183565863269658851Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183629102270291180Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183820656972206569Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183820656972206569Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183820656972206569Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183820656972206569Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183910367773103793Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183961991484638778Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184331112077311343Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184513060468778777Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184642328780423287Mouse
10412184Sstapa1_mSuseptibility to Staphylococus aureus infection 1 (mouse)Not determined184654154657590708Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184687490380875042Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184687490380875042Mouse
27226720Tibw5_mtibia width 5, proximal, 10 week (mouse)185043306762633071Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185105215685052311Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185105215685052311Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185166830085668468Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185166830085668468Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185280527686805416Mouse
1302050Radpf4_mradiation pulmonary fibrosis 4 (mouse)Not determined185296615668778777Mouse
4142443Pgis1_mproteoglycan induced spondylitis 1 (mouse)Not determined185329102276914293Mouse
4141431Msmr2_mMSM lymphoma resistance 2 (mouse)Not determined5497587361238870Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185497587385514143Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185643307190433071Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185643307190433071Mouse

Markers in Region
Aldh7a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv374115,592,679 - 115,593,284UniSTSGRCm37
MGSCv371856,686,450 - 56,686,631UniSTSGRCm37
Celera1857,829,993 - 57,830,174UniSTS
Celera4114,659,747 - 114,660,352UniSTS
Cytogenetic Map18D3UniSTS
cM Map454.8UniSTS
cM Map454.8UniSTS
cM Map454.8UniSTS
cM Map1829.0UniSTS
cM Map1829.0UniSTS
D18Wsu181e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18D3UniSTS
cM Map1829.0UniSTS
Aldh7a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381856,526,796 - 56,526,977UniSTSGRCm38
MGSCv371856,686,450 - 56,686,631UniSTSGRCm37
Celera1857,829,993 - 57,830,174UniSTS
Cytogenetic Map18D3UniSTS
cM Map1829.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003952489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_385969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY017676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ156580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000066208   ⟹   ENSMUSP00000065089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,659,816 - 56,695,381 (-)Ensembl
GRCm38.p6 Ensembl1856,526,744 - 56,562,309 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168517
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,665,611 - 56,670,689 (-)Ensembl
GRCm38.p6 Ensembl1856,532,539 - 56,537,617 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170309   ⟹   ENSMUSP00000127625
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,670,320 - 56,695,298 (-)Ensembl
GRCm38.p6 Ensembl1856,537,248 - 56,562,226 (-)Ensembl
RefSeq Acc Id: ENSMUST00000171844   ⟹   ENSMUSP00000127652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,683,439 - 56,695,269 (-)Ensembl
GRCm38.p6 Ensembl1856,550,367 - 56,562,197 (-)Ensembl
RefSeq Acc Id: ENSMUST00000171851
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,679,992 - 56,692,494 (-)Ensembl
GRCm38.p6 Ensembl1856,546,920 - 56,559,422 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172734   ⟹   ENSMUSP00000134192
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,659,677 - 56,695,400 (-)Ensembl
GRCm38.p6 Ensembl1856,526,605 - 56,562,328 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172902
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,642,759 - 56,659,921 (-)Ensembl
GRCm38.p6 Ensembl1856,509,687 - 56,526,849 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174518   ⟹   ENSMUSP00000133372
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,657,794 - 56,706,023 (-)Ensembl
GRCm38.p6 Ensembl1856,524,722 - 56,572,951 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174704   ⟹   ENSMUSP00000133970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1856,659,822 - 56,695,290 (-)Ensembl
GRCm38.p6 Ensembl1856,526,750 - 56,562,218 (-)Ensembl
RefSeq Acc Id: NM_001127338   ⟹   NP_001120810
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391856,658,808 - 56,706,011 (-)NCBI
GRCm381856,525,736 - 56,572,939 (-)NCBI
MGSCv371856,685,390 - 56,732,593 (-)RGD
Celera1857,828,935 - 57,877,977 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_138600   ⟹   NP_613066
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391856,658,808 - 56,695,370 (-)NCBI
GRCm381856,525,736 - 56,562,298 (-)NCBI
MGSCv371856,685,390 - 56,732,593 (-)RGD
Celera1857,828,935 - 57,877,977 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_003952489
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391856,657,794 - 56,706,112 (-)NCBI
GRCm381856,524,722 - 56,572,991 (-)NCBI
Sequence:
RefSeq Acc Id: XR_385969
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391856,657,794 - 56,695,398 (-)NCBI
GRCm381856,524,722 - 56,562,315 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_613066   ⟸   NM_138600
- Peptide Label: isoform a
- UniProtKB: Q3TVH7 (UniProtKB/Swiss-Prot),   Q3TFC7 (UniProtKB/Swiss-Prot),   Q3UKT6 (UniProtKB/Swiss-Prot),   Q9DBF1 (UniProtKB/Swiss-Prot),   G3UYR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120810   ⟸   NM_001127338
- Peptide Label: isoform b
- UniProtKB: G3UYR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000127625   ⟸   ENSMUST00000170309
RefSeq Acc Id: ENSMUSP00000065089   ⟸   ENSMUST00000066208
RefSeq Acc Id: ENSMUSP00000134192   ⟸   ENSMUST00000172734
RefSeq Acc Id: ENSMUSP00000127652   ⟸   ENSMUST00000171844
RefSeq Acc Id: ENSMUSP00000133372   ⟸   ENSMUST00000174518
RefSeq Acc Id: ENSMUSP00000133970   ⟸   ENSMUST00000174704
Protein Domains
Aldehyde dehydrogenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DBF1-F1-model_v2 AlphaFold Q9DBF1 1-539 view protein structure

Promoters
RGD ID:13677830
Promoter ID:EPDNEW_M23064
Type:initiation region
Name:Aldh7a1_1
Description:Mus musculus aldehyde dehydrogenase family 7, member A1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381856,572,872 - 56,572,932EPDNEW
RGD ID:6829484
Promoter ID:MM_KWN:25332
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_138600,   OTTMUST00000083078,   OTTMUST00000083079
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361856,721,716 - 56,722,247 (+)MPROMDB
RGD ID:6829068
Promoter ID:MM_KWN:25334
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Liver,   Lung,   Spleen
Transcripts:NM_001127338
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361856,732,561 - 56,733,322 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108186 AgrOrtholog
Ensembl Genes ENSMUSG00000053644 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066208 ENTREZGENE
  ENSMUST00000066208.13 UniProtKB/Swiss-Prot
  ENSMUST00000170309.8 UniProtKB/TrEMBL
  ENSMUST00000171844.3 UniProtKB/TrEMBL
  ENSMUST00000172734.8 UniProtKB/TrEMBL
  ENSMUST00000174518 ENTREZGENE
  ENSMUST00000174518.8 UniProtKB/Swiss-Prot
  ENSMUST00000174704.8 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDH7A1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110695 UniProtKB/Swiss-Prot
MGD MGI:108186 ENTREZGENE
NCBI Gene 110695 ENTREZGENE
PANTHER ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43521 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aldh7a1 PhenoGen
PROSITE ALDEHYDE_DEHYDR_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Aldehyde_DH/Histidinol_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AL7A1_MOUSE UniProtKB/Swiss-Prot
  E9Q1G1_MOUSE UniProtKB/TrEMBL
  E9Q1H3_MOUSE UniProtKB/TrEMBL
  G3UY72_MOUSE UniProtKB/TrEMBL
  G3UYR8 ENTREZGENE, UniProtKB/TrEMBL
  Q3TFC7 ENTREZGENE
  Q3TVH7 ENTREZGENE
  Q3UKT6 ENTREZGENE
  Q9DBF1 ENTREZGENE
UniProt Secondary Q3TFC7 UniProtKB/Swiss-Prot
  Q3TVH7 UniProtKB/Swiss-Prot
  Q3UKT6 UniProtKB/Swiss-Prot