Idh3a (isocitrate dehydrogenase 3 (NAD+) alpha) - Rat Genome Database

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Gene: Idh3a (isocitrate dehydrogenase 3 (NAD+) alpha) Mus musculus
Analyze
Symbol: Idh3a
Name: isocitrate dehydrogenase 3 (NAD+) alpha
RGD ID: 733178
MGI Page MGI
Description: Predicted to enable isocitrate dehydrogenase (NAD+) activity and magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39954,493,795 - 54,511,946 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl954,493,618 - 54,511,945 (+)EnsemblGRCm39 Ensembl
GRCm38954,586,511 - 54,604,662 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl954,586,334 - 54,604,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37954,434,318 - 54,452,469 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36954,384,648 - 54,402,799 (+)NCBIMGSCv36mm8
Celera951,829,728 - 51,847,959 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(+)-dexrazoxane  (EXP)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
apigenin  (EXP)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[ghi]perylene  (EXP)
berberine  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
bortezomib  (ISO)
Brodifacoum  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlormidazole  (ISO)
clofibrate  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (EXP)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dexamethasone  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
ethanol  (EXP)
fenthion  (EXP)
fenvalerate  (ISO)
flavonoids  (ISO)
fluoxastrobin  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
inulin  (EXP)
ivermectin  (ISO)
lamivudine  (EXP)
lead(0)  (ISO)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methidathion  (EXP)
methotrexate  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
microcystin RR  (ISO)
mitoxantrone  (EXP,ISO)
nickel atom  (ISO)
Nutlin-3  (ISO)
oxidopamine  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (EXP)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (EXP)
phenylmercury acetate  (ISO)
phlorizin  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
Propiverine  (ISO)
pyridaben  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
sodium nitrate  (EXP)
sulforaphane  (EXP)
T-2 toxin  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
tributylstannane  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trifloxystrobin  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zearalenone  (EXP)
zidovudine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Preparation and properties of mitochondria derived from synaptosomes. Lai JC and Clark JB, Biochem J. 1976 Feb 15;154(2):423-32.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14555658   PMID:14610273   PMID:14681479   PMID:15489334  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:17626619   PMID:17634366   PMID:17967808   PMID:18614015   PMID:18799693   PMID:19423573   PMID:19521500   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:22496890   PMID:27113764   PMID:27160897   PMID:27215380   PMID:27534441   PMID:27990575   PMID:28130547   PMID:28139779   PMID:28245920   PMID:29199018   PMID:29222160  
PMID:30068389   PMID:30457570   PMID:30478029   PMID:30550785   PMID:30562941   PMID:32290105   PMID:32325033   PMID:33986196   PMID:34709266   PMID:36114006   PMID:36293380   PMID:36417873  
PMID:37142655   PMID:37839992   PMID:38355793  


Genomics

Comparative Map Data
Idh3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39954,493,795 - 54,511,946 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl954,493,618 - 54,511,945 (+)EnsemblGRCm39 Ensembl
GRCm38954,586,511 - 54,604,662 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl954,586,334 - 54,604,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37954,434,318 - 54,452,469 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36954,384,648 - 54,402,799 (+)NCBIMGSCv36mm8
Celera951,829,728 - 51,847,959 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.7NCBI
IDH3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381578,149,362 - 78,171,945 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1578,131,498 - 78,171,945 (+)EnsemblGRCh38hg38GRCh38
GRCh371578,441,704 - 78,464,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,228,774 - 76,249,939 (+)NCBINCBI36Build 36hg18NCBI36
Build 341576,228,773 - 76,249,938NCBI
Celera1555,378,247 - 55,399,414 (+)NCBICelera
Cytogenetic Map15q25.1NCBI
HuRef1555,199,257 - 55,220,449 (+)NCBIHuRef
CHM1_11578,559,625 - 78,580,790 (+)NCBICHM1_1
T2T-CHM13v2.01576,011,920 - 76,034,530 (+)NCBIT2T-CHM13v2.0
Idh3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8863,867,882 - 63,887,223 (+)NCBIGRCr8
mRatBN7.2854,971,694 - 54,991,085 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl854,971,740 - 54,991,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx860,505,281 - 60,524,691 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0858,784,271 - 58,803,675 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0856,648,509 - 56,667,913 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0859,164,601 - 59,183,899 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl859,164,572 - 59,183,908 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0857,745,463 - 57,764,761 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,135,412 - 58,156,019 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1858,154,465 - 58,175,073 (+)NCBI
Celera854,460,353 - 54,479,655 (+)NCBICelera
Cytogenetic Map8q24NCBI
Idh3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955450685,905 - 703,586 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955450685,905 - 703,593 (+)NCBIChiLan1.0ChiLan1.0
IDH3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21667,362,996 - 67,384,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11571,528,667 - 71,550,063 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01557,078,588 - 57,099,934 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11576,043,311 - 76,064,634 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1576,043,311 - 76,064,634 (+)Ensemblpanpan1.1panPan2
IDH3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1358,301,982 - 58,318,925 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl358,302,001 - 58,318,248 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha360,993,181 - 61,010,332 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0358,769,639 - 58,786,830 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl358,748,159 - 58,786,830 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1358,266,135 - 58,283,304 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0358,474,154 - 58,491,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,823,194 - 58,840,363 (+)NCBIUU_Cfam_GSD_1.0
Idh3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640118,974,940 - 118,994,520 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647136,822,971 - 36,842,610 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647136,823,003 - 36,842,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IDH3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl747,759,439 - 47,778,956 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1747,759,436 - 47,778,948 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2753,312,283 - 53,330,719 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IDH3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1265,183,470 - 5,205,385 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl265,184,991 - 5,205,384 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048136,598,251 - 136,620,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Idh3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248942,662,434 - 2,679,232 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248942,661,509 - 2,679,071 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Idh3a
435 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:493
Count of miRNA genes:332
Interacting mature miRNAs:374
Transcripts:ENSMUST00000167866
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94754302457805204Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse

Markers in Region
AI316514  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38954,604,217 - 54,604,458UniSTSGRCm38
MGSCv37954,452,024 - 54,452,265UniSTSGRCm37
Celera951,847,514 - 51,847,755UniSTS
Cytogenetic Map9A5.3UniSTS
Whitehead/MRC_RH9544.24UniSTS
RH124560  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38954,603,772 - 54,603,853UniSTSGRCm38
MGSCv37954,451,579 - 54,451,660UniSTSGRCm37
Celera951,847,069 - 51,847,150UniSTS
Celera328,441,961 - 28,442,042UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map3A3UniSTS
RH125183  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38954,604,924 - 54,605,119UniSTSGRCm38
MGSCv37954,452,731 - 54,452,926UniSTSGRCm37
Celera951,848,221 - 51,848,416UniSTS
Cytogenetic Map9A5.3UniSTS
RH125646  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38954,603,651 - 54,603,900UniSTSGRCm38
MGSCv37954,451,458 - 54,451,707UniSTSGRCm37
Celera951,846,948 - 51,847,197UniSTS
Celera328,441,840 - 28,442,089UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map3A3UniSTS
Whitehead/MRC_RH9542.37UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_029573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK117103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  AK150618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  AK152353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  AK168049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  AK194060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  AK196914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  BC052208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
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  CT010507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000167866   ⟹   ENSMUSP00000127526
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl954,493,795 - 54,511,945 (+)Ensembl
GRCm38.p6 Ensembl954,586,511 - 54,604,661 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213729
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl954,493,794 - 54,499,624 (+)Ensembl
GRCm38.p6 Ensembl954,586,510 - 54,592,340 (+)Ensembl
Ensembl Acc Id: ENSMUST00000214136
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl954,502,378 - 54,511,220 (+)Ensembl
GRCm38.p6 Ensembl954,595,094 - 54,603,936 (+)Ensembl
Ensembl Acc Id: ENSMUST00000215273   ⟹   ENSMUSP00000149036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl954,493,765 - 54,511,229 (+)Ensembl
GRCm38.p6 Ensembl954,586,481 - 54,603,945 (+)Ensembl
Ensembl Acc Id: ENSMUST00000217484   ⟹   ENSMUSP00000150296
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl954,493,618 - 54,511,945 (+)Ensembl
GRCm38.p6 Ensembl954,586,334 - 54,604,661 (+)Ensembl
RefSeq Acc Id: NM_029573   ⟹   NP_083849
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39954,493,795 - 54,511,946 (+)NCBI
GRCm38954,586,511 - 54,604,662 (+)ENTREZGENE
MGSCv37954,434,318 - 54,452,469 (+)RGD
Celera951,829,728 - 51,847,959 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_083849   ⟸   NM_029573
- Peptide Label: precursor
- UniProtKB: Q8C8A1 (UniProtKB/Swiss-Prot),   Q3UAM8 (UniProtKB/Swiss-Prot),   Q9D1L1 (UniProtKB/Swiss-Prot),   Q9D6R2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000150296   ⟸   ENSMUST00000217484
Ensembl Acc Id: ENSMUSP00000127526   ⟸   ENSMUST00000167866
Ensembl Acc Id: ENSMUSP00000149036   ⟸   ENSMUST00000215273
Protein Domains
Isopropylmalate dehydrogenase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D6R2-F1-model_v2 AlphaFold Q9D6R2 1-366 view protein structure

Promoters
RGD ID:6844678
Promoter ID:MM_KWN:57439
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000034818,   UC009PRH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36954,434,096 - 54,434,596 (+)MPROMDB
RGD ID:6844682
Promoter ID:MM_KWN:57440
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4
Transcripts:UC009PRI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36954,441,661 - 54,442,161 (+)MPROMDB
RGD ID:8669640
Promoter ID:EPDNEW_M12851
Type:initiation region
Name:Idh3a_1
Description:Mus musculus isocitrate dehydrogenase 3 (NAD+) alpha , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38954,586,481 - 54,586,541EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915084 AgrOrtholog
Ensembl Genes ENSMUSG00000032279 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000167866 ENTREZGENE
  ENSMUST00000167866.2 UniProtKB/Swiss-Prot
  ENSMUST00000215273.2 UniProtKB/TrEMBL
  ENSMUST00000217484.2 UniProtKB/TrEMBL
Gene3D-CATH Isopropylmalate Dehydrogenase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IsoCit/isopropylmalate_DH_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Isocitrate_DH_NAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IsoPropMal-DH-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67834 UniProtKB/Swiss-Prot
MGD MGI:1915084 ENTREZGENE
NCBI Gene 67834 ENTREZGENE
PANTHER DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Iso_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Idh3a PhenoGen
PROSITE IDH_IMDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Iso_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Isocitrate/Isopropylmalate dehydrogenase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQF9_MOUSE UniProtKB/TrEMBL
  A0A1L1STE6_MOUSE UniProtKB/TrEMBL
  IDH3A_MOUSE UniProtKB/Swiss-Prot
  Q3UAM8 ENTREZGENE
  Q8C8A1 ENTREZGENE
  Q9D1L1 ENTREZGENE
  Q9D6R2 ENTREZGENE
UniProt Secondary Q3UAM8 UniProtKB/Swiss-Prot
  Q8C8A1 UniProtKB/Swiss-Prot
  Q9D1L1 UniProtKB/Swiss-Prot