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Gene: Nras (neuroblastoma ras oncogene) Mus musculus
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Symbol: Nras
Name: neuroblastoma ras oncogene
Description: Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including T cell receptor signaling pathway; defense response to protozoan; and positive regulation of interferon-gamma production. Localizes to membrane. Is expressed in several structures, including central nervous system; early embryo; eye; heart; and metanephros. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 6; autoimmune lymphoproliferative syndrome type 4; endocrine gland cancer (multiple); epidermal nevus; and hematologic cancer (multiple). Orthologous to human NRAS (NRAS proto-oncogene, GTPase); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; Fc epsilon receptor mediated signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV095280; GTPase NRas; N-ras; transforming protein N-Ras
Orthologs:
Homo sapiens (human) : NRAS (NRAS proto-oncogene, GTPase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nras (NRAS proto-oncogene, GTPase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nras (NRAS proto-oncogene, GTPase)
Pan paniscus (bonobo/pygmy chimpanzee) : NRAS (NRAS proto-oncogene, GTPase)
Canis lupus familiaris (dog) : NRAS (NRAS proto-oncogene, GTPase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nras (NRAS proto-oncogene, GTPase)
Sus scrofa (pig) : NRAS (NRAS proto-oncogene, GTPase)
Chlorocebus sabaeus (African green monkey) : NRAS (NRAS proto-oncogene, GTPase)
Heterocephalus glaber (naked mole-rat) : Nras (NRAS proto-oncogene, GTPase)
more info ...
Related Pseudogenes: Nras-ps1   Nras-ps2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl3103,058,285 - 103,067,914 (+)EnsemblGRCm38mm10GRCm38
GRCm383103,058,285 - 103,067,914 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373102,862,208 - 102,871,837 (+)NCBIGRCm37mm9NCBIm37
MGSCv363103,187,290 - 103,197,396 (+)NCBImm8
Celera3105,263,160 - 105,272,744 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nras
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11018
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.