Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ANAPC5 mRNA | CTD | PMID:23649840 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ANAPC5 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of ANAPC5 mRNA] | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of ANAPC5 mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ANAPC5 mRNA more ... | CTD | PMID:15034205 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Anapc5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ANAPC5 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ANAPC5 mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ANAPC5 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ANAPC5 mRNA | CTD | PMID:18796159 | 2,6-dinitrotoluene | affects expression | ISO | Anapc5 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of ANAPC5 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ANAPC5 mRNA | CTD | PMID:20188158 | 4,4'-diaminodiphenylmethane | affects expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of ANAPC5 mRNA | CTD | PMID:18648102 | 4-nitrophenol | decreases expression | EXP | | 6480464 | 4-nitrophenol results in decreased expression of ANAPC5 mRNA | CTD | PMID:34673133 | 7,12-dimethyltetraphene | increases expression | EXP | | 6480464 | 9 more ... | CTD | PMID:21785161 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of ANAPC5 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ANAPC5 mRNA | CTD | PMID:17218384 | all-trans-retinoic acid | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ANAPC5 mRNA | CTD | PMID:33167477 | Aroclor 1254 | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of ANAPC5 mRNA | CTD | PMID:16934159 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of ANAPC5 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ANAPC5 mRNA | CTD | PMID:15034205 | bisphenol A | increases expression | ISO | Anapc5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ANAPC5 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Anapc5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ANAPC5 mRNA | CTD | PMID:33296240 | bisphenol A | increases methylation | ISO | Anapc5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of ANAPC5 gene | CTD | PMID:28505145 | bortezomib | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of ANAPC5 mRNA | CTD | PMID:20977926 | bortezomib | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of ANAPC5 mRNA | CTD | PMID:17895889 | butan-1-ol | multiple interactions | ISO | ANAPC5 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of ANAPC5 mRNA | CTD | PMID:29432896 | caffeine | decreases phosphorylation | ISO | ANAPC5 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ANAPC5 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | ANAPC5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ANAPC5 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of ANAPC5 mRNA | CTD | PMID:37019170 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANAPC5 gene | CTD | PMID:20938992 | copper atom | multiple interactions | ISO | ANAPC5 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of ANAPC5 mRNA | CTD | PMID:30911355 | copper(0) | multiple interactions | ISO | ANAPC5 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of ANAPC5 mRNA | CTD | PMID:30911355 | copper(II) sulfate | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ANAPC5 mRNA | CTD | PMID:19549813 | coumestrol | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of ANAPC5 mRNA | CTD | PMID:19167446 | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of ANAPC5 mRNA | CTD | PMID:29279043 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ANAPC5 mRNA | CTD | PMID:17361019 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of ANAPC5 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of ANAPC5 mRNA | CTD | PMID:34813904 | flutamide | decreases expression | ISO | Anapc5 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of ANAPC5 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANAPC5 gene more ... | CTD | PMID:20938992 and PMID:22206623 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of ANAPC5 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ANAPC5 mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | ANAPC5 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of ANAPC5 protein | CTD | PMID:37730182 | glyphosate | decreases methylation | ISO | Anapc5 (Rattus norvegicus) | 6480464 | Glyphosate results in decreased methylation of ANAPC5 gene | CTD | PMID:31011160 | glyphosate | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Glyphosate results in decreased expression of ANAPC5 mRNA | CTD | PMID:31295307 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANAPC5 gene | CTD | PMID:20938992 | lead(0) | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Lead results in decreased expression of ANAPC5 mRNA | CTD | PMID:19921347 | mercury dichloride | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of ANAPC5 mRNA | CTD | PMID:27188386 | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of ANAPC5 mRNA | CTD | PMID:34813904 | methoxychlor | affects methylation | ISO | Anapc5 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of ANAPC5 gene | CTD | PMID:35440735 | methylparaben | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | methylparaben results in increased expression of ANAPC5 mRNA | CTD | PMID:31745603 | N-methyl-4-phenylpyridinium | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ANAPC5 mRNA | CTD | PMID:24810058 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANAPC5 mRNA] | CTD | PMID:17854601 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of ANAPC5 mRNA | CTD | PMID:17854601 | paracetamol | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ANAPC5 mRNA | CTD | PMID:21420995 | phenobarbital | affects expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ANAPC5 mRNA | CTD | PMID:19159669 | phlorizin | decreases expression | EXP | | 6480464 | Phlorhizin results in decreased expression of ANAPC5 mRNA | CTD | PMID:22538082 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ANAPC5 mRNA | CTD | PMID:17426115 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ANAPC5 mRNA | CTD | PMID:18301758 and PMID:21318169 | pirinixic acid | multiple interactions | EXP | | 6480464 | PPARA protein affects the reaction [pirinixic acid results in increased expression of ANAPC5 mRNA] | CTD | PMID:21318169 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of ANAPC5 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of ANAPC5 mRNA | CTD | PMID:15336504 | testosterone enanthate | affects expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of ANAPC5 mRNA | CTD | PMID:17440010 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of ANAPC5 mRNA | CTD | PMID:19042947 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of ANAPC5 mRNA | CTD | PMID:35537566 | valproic acid | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ANAPC5 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ANAPC5 mRNA | CTD | PMID:25979313 | vincristine | increases expression | ISO | ANAPC5 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ANAPC5 mRNA | CTD | PMID:23649840 | |