Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hepatocellular carcinoma
go back to main search page
Accession:DOID:684 term browser browse the term
Definition:A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver. (DO)
Synonyms:exact_synonym: Childhood Hepatocellular Carcinoma;   HCC;   Hepatocellular Cancer;   Hepatocellular Carcinoma, Childhood Type, Somatic;   LCC;   adult liver cancer;   adult liver cancers;   hepatocellular cancers;   hepatocellular carcinomas;   hepatoma;   hepatomas;   liver cell carcinoma;   liver cell carcinomas
 narrow_synonym: HEPATOBLASTOMA;   HEPATOBLASTOMA CAUSED BY SOMATIC MUTATION;   hepatitis B virus induced hepatocellular carcinoma;   hepatitis C virus induced hepatocellular carcinoma;   hepatitis virus-related hepatocellular carcinoma
 primary_id: MESH:D006528
 alt_id: OMIM:114550
 xref: EFO:0000182;   EFO:0000189;   EFO:0008503;   EFO:0008504;   EFO:0008505;   ICD-O:M8170/3;   NCI:C129298;   NCI:C24029;   NCI:C3099;   NCI:C38756;   NCI:C60416;   ORDO:88673
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IEP
ISO		 mRNA,protein:increased expression:liver:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15509519 PMID:15509519 RGD:1358261 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Aadat aminoadipate aminotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 severity IEP
ISO		 mRNA:decreased expression:liver (human) RGD PMID:16941710 PMID:30580964 RGD:1598532, RGD:24922199 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility IEP
ISO		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism: : c.1465C > T(human)
DNA:polymorphism: :c.3751G>A(human)		 CTD
RGD		 PMID:17510421 PMID:25625052 PMID:23488625 PMID:24175826 RGD:11041138, RGD:14700904, RGD:14700905 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 ISO
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:22022477 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 IEP mRNA:increased expression:liver RGD PMID:25842354 RGD:11535155 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 ISO mRNA:increased expression:liver (human) RGD PMID:21932399 RGD:11041873 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:32171747 RGD:126907997 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO CTD Direct Evidence: therapeutic
DNA:insertion/deletion:intron 16:		 CTD
RGD		 PMID:16328049 PMID:25208933 RGD:11343535 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acer3 alkaline ceramidase 3 disease_progression ISO RGD PMID:30097213 RGD:35673325 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Acly ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Aco2 aconitase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acox1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12771043 PMID:15565109 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Actb actin, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:21472284 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:10,299,264...10,338,464
Ensembl chr 3:10,300,028...10,346,687 		JBrowse link
G Add1 adducin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing susceptibility ISO DNA:SNP:intron:+276T>G (rs1501299) (human) RGD PMID:23740135 RGD:14401720 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adra1a adrenoceptor alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra2b adrenoceptor alpha 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Afp alpha-fetoprotein severity
disease_progression
treatment		 ISO
IEP		 protein:increased expression:serum (human)
associated with hepatitis B
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9029167 PMID:15276417 PMID:24012840 PMID:28284560 PMID:32961231 More... RGD:14401581, RGD:126790579, RGD:126790583, RGD:125097525, RGD:152177911 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Aicda activation-induced cytidine deaminase ISO RGD PMID:18997814 RGD:127285629 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Ak3 adenylate kinase 3 ISO protein:decreased expression:liver RGD PMID:17203974 RGD:13842477 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32805337 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 ISO
IEP		 protein:increased expression:liver (human)
protein:increased expression:liver (rat)		 RGD PMID:19422879 PMID:21683810 RGD:8548685, RGD:5509919 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular cancer		 CTD
ClinVar
RGD		 PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... RGD:151893509, RGD:152177911 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEP
ISO		 protein:increased phosphorylation:liver cancer cell (rat)
protein:increased phosphorylation:liver (mouse)		 RGD PMID:19309364 PMID:28100771 RGD:2313299, RGD:127285675 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alb albumin susceptibility ISO associated with hepatitis C;protein:decreased expression:serum
protein:decreased expression:serum (human)		 RGD PMID:23892757 PMID:29040987 PMID:22392353 RGD:11035269, RGD:14694841, RGD:125097525 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
severity
no_association		 ISO associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human)
DNA:missense mutation:cds, exon 12:p.E487K (human)
associated with hepatitis C:DNA:SNP:exon 12 (human)
protein:decreased expression: liver (human)
mRNA, protein:decreased expression:liver (human)
DNA:missense mutation:cds: (rs671) (human)
associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human)
DNA:missense mutation:exon 12: (human)
associated with alcohol use disorder;DNA:missense mutation:cds: (human)		 RGD PMID:25778454 PMID:1916152 PMID:12940444 PMID:26150517 PMID:28027570 More... RGD:11054822, RGD:14696699, RGD:14696778, RGD:14696779, RGD:15036809, RGD:14700899, RGD:15042857, RGD:15042859, RGD:15042862 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C IEP mRNA:increased expression:liver RGD PMID:3830170 RGD:2301136 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alx4 ALX homeobox 4 ameliorates ISO
IEP		 mRNA, protein:decreased expression:liver RGD PMID:28081728 PMID:31132711 PMID:31132711 RGD:153323329, RGD:153323330, RGD:153323330 NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Angptl6 angiopoietin-like 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925 		JBrowse link
G Ank3 ankyrin 3 ISO protein:decreased expression:liver RGD PMID:26652480 RGD:153344559 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Anln anillin, actin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538 		JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 treatment ISO RGD PMID:20650339 RGD:9684932 NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232 		JBrowse link
G Anxa10 annexin A10 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Anxa2 annexin A2 ISO mRNA, protein:increased expression:liver (human) RGD PMID:33675609 RGD:152999436 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Anxa6 annexin A6 disease_progression ISO associated with tumor vascularization; protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO
ISS		 DNA:hypermethylation
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD Direct Evidence: marker/mechanism
OMIM:114550		 OMIM
ClinVar
CTD
MouseDO
RGD		 PMID:1316610 PMID:8381579 PMID:8381580 PMID:9536098 PMID:9824584 More... RGD:14402050 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25109342 PMID:33841550 RGD:152998960 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apln apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apoa1 apolipoprotein A1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma (human)
associated with hepatitis B;		 CTD
RGD		 PMID:21472284 PMID:23935864 PMID:31211449 RGD:25671438, RGD:153350082 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 ISO associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 disease_progression ISO associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoc1 apolipoprotein C1 disease_progression ISO associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 ISO associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 susceptibility
disease_progression		 ISO associated with Chronic Hepatitis B;DNA:SNP: :rs2854116(human)
associated with hepatitis B;		 RGD PMID:27547913 PMID:31211449 RGD:153344620, RGD:153350082 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apoc4 apolipoprotein C4 disease_progression ISO associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981 		JBrowse link
G Apoe apolipoprotein E ISO protein:increased expression:liver, serum (mouse) RGD PMID:21644509 RGD:6903288 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apof apolipoprotein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946 		JBrowse link
G Aprt adenine phosphoribosyl transferase IEP protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431 		JBrowse link
G Ar androgen receptor ISO CTD Direct Evidence: therapeutic CTD PMID:18639551 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arg1 arginase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:17210712 PMID:30901224 RGD:4140476, RGD:152995286 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap11a Rho GTPase activating protein 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 exacerbates ISO protein:decreased expression:liver (human) RGD PMID:31136984 RGD:401901276 NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Arhgef39 Rho guanine nucleotide exchange factor 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:57,752,509...57,756,079
Ensembl chr 5:57,752,509...57,756,109 		JBrowse link
G Arid1a AT-rich interaction domain 1A treatment
exacerbates		 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human)
mRNA, protein:decreased expression:liver (human)
associated with non-alcoholic steatohepatitis
human gene in mouse model		 CTD
RGD		 PMID:22561517 PMID:22634756 PMID:22922871 PMID:26589513 PMID:25975202 More... RGD:125097485, RGD:125097495, RGD:125097519, RGD:11344640, RGD:126790634, RGD:126790634 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Arid1b AT-rich interaction domain 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493 		JBrowse link
G Arid2 AT-rich interaction domain 2 disease_progression
exacerbates		 ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B;protein:decreased expression:liver		 CTD
RGD		 PMID:21822264 PMID:22634756 PMID:32071245 PMID:27351279 PMID:28498550 More... RGD:150340708, RGD:150340711, RGD:150340712, RGD:150429631 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Arid3a AT-rich interaction domain 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:35179300 NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599 		JBrowse link
G Arrb2 arrestin, beta 2 treatment IEP RGD PMID:33841550 RGD:152998960 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Asl argininosuccinate lyase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) IEP protein:increased activity:serum (rat) RGD PMID:10081 RGD:2316006 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268 		JBrowse link
G Aspm assembly factor for spindle microtubules disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:18676753 RGD:13439743 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755 		JBrowse link
G Ass1 argininosuccinate synthase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:12359751 PMID:30901224 RGD:4140479, RGD:152995286 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atg101 autophagy related 101 disease_progression ISO RGD PMID:35592424 RGD:153350091 NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633 		JBrowse link
G Atg7 autophagy related 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29191453 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atm ATM serine/threonine kinase exacerbates ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)		 CTD
RGD		 PMID:12866955 PMID:19919837 RGD:126781750 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b ISO associated with hepatitis C RGD PMID:18932288 RGD:14696822 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atp7b ATPase copper transporting beta onset IAGP RGD PMID:8291609 RGD:15036817 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis onset IAGP RGD PMID:8291609 RGD:15036817
G Aurka aurora kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Axin1 axin 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
associated with Hepatitis B, Chronic,DNA:SNP, haplotype:exon:(rs1805105) T>C (human)
protein:decreased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma		 OMIM
CTD
ClinVar
RGD		 PMID:10700176 PMID:25741868 PMID:25741905 PMID:25822088 PMID:28492532 More... RGD:1300371, RGD:14402039, RGD:150530481, RGD:150530482 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 ISO protein:increased expression:liver: RGD PMID:11809809 RGD:151356508 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO
IEP		 mRNA:decreased expression:liver RGD PMID:22625427 PMID:27993894 PMID:26902423 RGD:153350130, RGD:153350132, RGD:153350133 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Azin1 antizyme inhibitor 1 disease_progression ISO RNA:increased editing:liver RGD PMID:23291631 RGD:14700705 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578 		JBrowse link
G Banf1 BAF nuclear assembly factor 1 treatment IEP
ISO		 mRNA, protein:increased expression:liver (rat)
mRNA, protein:increased expression:liver (human)		 RGD PMID:29059470 PMID:29059470 PMID:29059470 RGD:155791679, RGD:155791679, RGD:155791679 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:33841550 RGD:152998960 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment ISO
IEP		 mRNA:increased expression:liver (mouse) RGD PMID:28100771 PMID:33841550 RGD:127285675, RGD:152998960 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (mouse)		 CTD
RGD		 PMID:10629087 PMID:11509945 PMID:28100771 PMID:33841550 RGD:127285675, RGD:152998960 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bco2 beta-carotene oxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 disease_progression ISO RGD PMID:29679906 PMID:26879601 RGD:150340705, RGD:11556159 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Bid BH3 interacting domain death agonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:15289866 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ameliorates
exacerbates
treatment		 ISO human cell line in a mouse model
associated with hepatitis B;mRNA, protein:increased expression:liver (human)		 RGD PMID:30368883 PMID:22682366 PMID:22820591 PMID:33310033 PMID:30210622 RGD:152998937, RGD:152998984, RGD:152998986, RGD:152998988, RGD:152999010 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:16086872 PMID:20514400 PMID:31964418 RGD:153344516 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 exacerbates ISO mRNA:increased expression:liver (human) RGD PMID:31964418 RGD:153344516 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Blzf1 basic leucine zipper nuclear factor 1 disease_progression ISO RGD PMID:26342799 RGD:14398326 NCBI chr13:76,641,757...76,656,977
Ensembl chr13:76,641,515...76,656,999 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger treatment ISO RGD PMID:26919246 RGD:14928318 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Bmper BMP-binding endothelial regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27222248 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Bsg basigin (Ok blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18393292 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C3 complement C3 IEP RGD PMID:23245919 RGD:11040806 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C6h14orf180 similar to human chromosome 14 open reading frame 180 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:131,557,193...131,568,245
Ensembl chr 6:131,559,690...131,567,342 		JBrowse link
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Cab39 calcium binding protein 39 disease_progression ISO RGD PMID:28605041 PMID:28605041 RGD:14398832, RGD:14398832 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP
IAGP		 mRNA:increased expression:liver
DNA:amplification:cds (rat)		 RGD PMID:2888462 PMID:2914957 PMID:7053379 RGD:2303530, RGD:5132587, RGD:10755426 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cadm1 cell adhesion molecule 1 IEP DNA, mRNA, protein:hypermethylation, decreased expression:promoter:liver RGD PMID:17428255 RGD:2289095 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Cadm2 cell adhesion molecule 2 disease_progression ISO mRNA, protein:decreased expression:liver RGD PMID:24240726 RGD:15092075 NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400 		JBrowse link
G Calml3 calmodulin-like 3 severity ISO protein:decreased expression:liver (human) RGD PMID:29445139 RGD:151665319 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Calr calreticulin exacerbates
treatment		 ISO protein:increased expression:liver (human)
human cells and recombinant gene in a mouse model		 RGD PMID:27055635 PMID:12096119 PMID:24997628 RGD:150521681, RGD:150521690, RGD:150521691 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 ISO RGD PMID:23651211 RGD:18337283 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373 		JBrowse link
G Capn3 calpain 3 IEP mRNA:decreased expression:skeletal muscle RGD PMID:10806331 RGD:1600777 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Car12 carbonic anhydrase 12 disease_progression
ameliorates		 ISO mRNA:altered expression:liver RGD PMID:35362480 PMID:35362480 PMID:31934040 PMID:29900055 RGD:153352325, RGD:153352325, RGD:153352328, RGD:155226869 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Car2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car9 carbonic anhydrase 9 ISO mRNA:altered expression:liver RGD PMID:29900055 RGD:155226869 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 IEP mRNA,protein:increased expression:liver: RGD PMID:23912631 RGD:9586718 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:29133031 PMID:33841550 RGD:13782296, RGD:152998960 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment
severity		 ISO
IEP		 associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human)
CTD Direct Evidence: marker/mechanism		 OMIM
CTD
RGD		 PMID:29133031 PMID:28643196 RGD:13782296, RGD:14695027 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:29133031 RGD:13782296 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase disease_progression ISO associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:33010264 PMID:21907168 RGD:27095879 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbfb core-binding factor subunit beta ISO mRNA:decreased expression:liver RGD PMID:17094378 RGD:126775147 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Cbl Cbl proto-oncogene disease_progression ISO RGD PMID:26474280 RGD:11536137 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21056497 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbx2 chromobox 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383 		JBrowse link
G Cbx4 chromobox 4 disease_progression ISO protein:increased expression:cytoplasm: RGD PMID:24838576 PMID:23943028 RGD:9586738, RGD:9586739 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706 		JBrowse link
G Cbx7 chromobox 7 ISO mRNA:decreased expression:liver RGD PMID:22041561 RGD:9587355 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RNA:increased expression:liver RGD PMID:27980102 PMID:27980102 PMID:12679798 PMID:22402625 RGD:14995459, RGD:14995459, RGD:14995468, RGD:14995927 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment
susceptibility		 ISO DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human)		 RGD PMID:28011329 PMID:22374185 PMID:21610221 RGD:14995306, RGD:14995333, RGD:14995338 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17699798 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccna1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnb1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human)
mRNA:increased expression:liver (mouse)		 CTD
RGD		 PMID:12029619 PMID:19919837 PMID:22649188 PMID:25822088 PMID:26189965 More... RGD:14401586, RGD:127285675 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 severity
disease_progression
susceptibility		 ISO associated with hepatitis B
DNA:hypermethylation:CpG site
associated with Chronic Hepatitis C;DNA:SNP: :rs1049606(human)		 RGD PMID:33320844 PMID:33320844 PMID:31059558 PMID:22004425 RGD:151664743, RGD:151664743, RGD:151665109, RGD:151665169 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccne1 cyclin E1 ameliorates IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12029619 PMID:22634754 PMID:17196522 PMID:28100771 PMID:29551768 RGD:2289277, RGD:127285675, RGD:153297807 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccnf cyclin F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Ccng1 cyclin G1 treatment
disease_progression
severity		 IGI
IEP
ISO		 protein:increased expression:liver (human)
human cells in mouse model
protein:decreased expression:liver (human)		 RGD PMID:25431954 PMID:24034575 PMID:26345095 PMID:23804702 PMID:23804702 More... RGD:151356922, RGD:151356932, RGD:151356933, RGD:151356967, RGD:151356967, RGD:151356970, RGD:151356981, RGD:151361198, RGD:151361200 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccng2 cyclin G2 ISO RGD PMID:27982046 RGD:151361200 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd163 CD163 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd274 CD274 molecule disease_progression ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B
associated with hepatitis B		 CTD
RGD		 PMID:22396772 PMID:30267213 PMID:21912640 RGD:40818240, RGD:41410800 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd276 Cd276 molecule ISO CTD Direct Evidence: therapeutic CTD PMID:16217749 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd34 CD34 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd40lg CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd5l Cd5 molecule-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Cd68 Cd68 molecule severity ISO protein:increased expression:liver (human) RGD PMID:28656201 RGD:40924686 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cdc20 cell division cycle 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc25c cell division cycle 25C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc27 cell division cycle 27 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cdc45 cell division cycle 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc6 cell division cycle 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca2 cell division cycle associated 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca3 cell division cycle associated 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca5 cell division cycle associated 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca8 cell division cycle associated 8 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 severity IDA
ISO		 DNA:hypermethylation
mRNA:increased expression:liver
protein:decreased expression:liver		 RGD PMID:17295234 PMID:30697077 PMID:30697077 PMID:24840851 PMID:18837082 RGD:2289638, RGD:14402045, RGD:14402045, RGD:14402046, RGD:14402047 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18425332 PMID:18553387 PMID:28284560 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 ISO protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28284560 PMID:19136513 RGD:2316317 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 exacerbates ISO mRNA, protein:increased expression:liver (human) RGD PMID:31519701 RGD:151361172 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 onset ISO DNA:amplification: : RGD PMID:22912832 RGD:155641228 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721 		JBrowse link
G Cdk14 cyclin-dependent kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26189965 PMID:33841550 RGD:152998960 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISS OMIM:114550 MouseDO NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20698225 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C severity ISO protein:decreased expression:liver (human) RGD PMID:26606000 RGD:11354707 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A severity IEP
IDA
ISO		 Protein:increased expression:liver
DNA:hypermethylation:promoter
DNA:hypermethylation:exon
Protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA		 RGD
CTD
ClinVar		 PMID:7780957 PMID:8521414 PMID:9185756 PMID:9324288 PMID:10491434 More... RGD:1600816, RGD:1600816, RGD:1600822, RGD:8552680 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 IEP Protein:decreased expression:liver RGD PMID:16317707 RGD:1600816
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 severity
treatment		 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver
protein:decreased expression:liver
associated with alcoholism; protein:increased expression:liver		 CTD
RGD		 PMID:28284560 PMID:22390936 PMID:27314282 PMID:23292002 PMID:23292002 RGD:15090800, RGD:15090801, RGD:15090802, RGD:15090802 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16288022 PMID:21785164 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO CTD Direct Evidence: marker/mechanism
mRNA: increased expression:liver (human)		 CTD
RGD		 PMID:14563831 PMID:30659195 RGD:40903042 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354 		JBrowse link
G Cenpa centromere protein A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:21956590 RGD:36947377 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpe centromere protein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cenpf centromere protein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenpm centromere protein M ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258 		JBrowse link
G Cenpu centromere protein U ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cenpw centromere protein W ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cep131 centrosomal protein 131 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,346,015...105,370,380 		JBrowse link
G Cep164 centrosomal protein 164 susceptibility ISO associated with Chronic Hepatitis C;DNA:SNP: :rs573455 (human) RGD PMID:22004425 RGD:151665169 NCBI chr 8:46,070,901...46,134,511
Ensembl chr 8:46,071,076...46,134,336 		JBrowse link
G Cep55 centrosomal protein 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394 		JBrowse link
G Ces1d carboxylesterase 1D disease_progression ISO protein:decreased expression:liver (human)
mRNA, protein:decreased expression:liver tumor (human)
associated with tumor vascularization; protein:decreased expression:liver tumor (human)		 RGD PMID:24259486 PMID:19658107 PMID:30901224 RGD:152995276, RGD:152995279, RGD:152995286 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfp complement factor properdin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573 		JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 exacerbates ISO mRNA:increased expression:liver (human)
protein:increased expression:liver (human)		 RGD PMID:28486105 PMID:26095183 RGD:153323299, RGD:11571740 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 ISO mRNA:decreased expression:liver RGD PMID:26517514 RGD:11537550 NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291 		JBrowse link
G Ckap2l cytoskeleton associated protein 2-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366 		JBrowse link
G Ckap4 cytoskeleton-associated protein 4 disease_progression ISO associated with tumor vascularization; mRNA,protein:increased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914 		JBrowse link
G Cldn1 claudin 1 severity IEP protein:increased expression:liver (human)
protein:decreased expression:liver (human)
associated with liver cirrhosis;protein:increased expression:liver (human)		 RGD PMID:24815833 PMID:17270214 PMID:24696415 RGD:26884345, RGD:26884348, RGD:26884352 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Clec1b C-type lectin domain family 1, member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291 		JBrowse link
G Clec4g C-type lectin domain family 4, member G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Clec4m C-type lectin domain family 4 member M ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539 		JBrowse link
G Clptm1l CLPTM1-like susceptibility
disease_progression		 ISO DNA:SNPs::rs401681(human)
DNA:SNP: :rs401681(human)		 RGD PMID:25339005 PMID:29042796 RGD:150530496, RGD:150537100 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cltrn collectrin, amino acid transport regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:30,361,967...30,395,264
Ensembl chr  X:30,361,967...30,395,349 		JBrowse link
G Cndp1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100 		JBrowse link
G Cntnap4 contactin associated protein family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:40,568,684...40,861,879
Ensembl chr19:40,568,684...40,854,656 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain severity IDA Protein:increased expression RGD PMID:15739185 RGD:1600906 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Colec10 collectin subfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675 		JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cops5 COP9 signalosome subunit 5 severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)		 CTD
RGD		 PMID:20698225 PMID:26606000 RGD:11354707 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731 		JBrowse link
G Cox7b2 cytochrome c oxidase subunit 7B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:36,693,120...36,805,323
Ensembl chr14:36,693,105...36,805,523 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19229483 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf1r colony stimulating factor 1 receptor severity
exacerbates		 ISO DNA:hypomethylation:promoter (human)
protein:increased expression: liver (human)
protein:increased expression:liver (human)		 RGD PMID:32724427 PMID:32760707 PMID:11412385 PMID:14969845 RGD:150524282, RGD:150524286, RGD:150524301, RGD:150524302 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO RGD PMID:12731087 RGD:10450243 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csk C-terminal Src kinase IEP protein:decreased expression:liver RGD PMID:9918913 RGD:5134372 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO protein:increased expression:CD4+ and CD8+ T cells:
DNA:SNPs: :rs231775,rs231725(human)		 RGD PMID:28648905 PMID:23432218 RGD:14398741, RGD:14398742 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Ctnnb1 catenin beta 1 susceptibility
severity
exacerbates		 ISO DNA:mutation:exon 3
CTD Direct Evidence: marker/mechanism
associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human)
associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human)
protein:increased expression:liver:
DNA:Mutations:exon:
DNA:missense mutations:exon 3:multiple (human)
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA		 OMIM
CTD
ClinVar
RGD		 PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... RGD:734850, RGD:14402039, RGD:14402040, RGD:14402052, RGD:14402052, RGD:150429592 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsb cathepsin B IDA RGD PMID:15641152 RGD:2315605 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsl cathepsin L IDA RGD PMID:15641152 RGD:2315605 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cux1 cut-like homeobox 1 ISO mRNA:increased expression:liver (human) RGD PMID:30561038 RGD:152985541 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 disease_progression
treatment		 ISO RGD PMID:28592115 PMID:28638480 PMID:27245433 RGD:27095889, RGD:27095898, RGD:27095899 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 treatment
severity		 ISO human cells in mouse model
protein:increased expression:liver (human)		 RGD PMID:30034941 PMID:33574707 RGD:151665331, RGD:151665327 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21109933 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 susceptibility ISO associated with hepatitis C; DNA:polymorphisms: : RGD PMID:11021356 RGD:124713413 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism
associated with alcohol dependence
DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human)		 CTD
RGD		 PMID:15162526 PMID:20364586 PMID:29765251 RGD:14700882, RGD:14700899 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Dab2ip DAB2 interacting protein severity ISO mRNA:decreased expression:liver (human)
protein:decreased expression:liver (human)		 RGD PMID:31176165 PMID:22168621 RGD:151665110, RGD:151665148 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dbh dopamine beta-hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dcn decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA:increased expression:liver (human) RGD PMID:33173221 PMID:33173221 RGD:151347691, RGD:151347691 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 treatment
disease_progression		 ISO RGD PMID:33969575 PMID:26362312 RGD:150429748, RGD:11086753 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked exacerbates
sexual_dimorphism 		ISO associated with hepatitis B; mRNA,protein:decreased expression:liver (human) RGD PMID:30297359 PMID:16301996 RGD:151356499, RGD:151356660 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Depdc1 DEP domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951 		JBrowse link
G Depdc1b DEP domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779 		JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21725309 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794 		JBrowse link
G Dhfr dihydrofolate reductase ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:28492532 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dicer1 dicer 1 ribonuclease III susceptibility ISO associated with hepatitis B; DNA:SNP: :rs1057035 T>C (human) RGD PMID:23868705 RGD:149735346 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dipk2b divergent protein kinase domain 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:4,205,486...4,274,939
Ensembl chr  X:4,205,490...4,271,574 		JBrowse link
G Diras3 DIRAS family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:130,524,972...130,526,186
Ensembl chr 6:130,524,742...130,530,825 		JBrowse link
G Dlgap5 DLG associated protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP mRNA, protein:increased expression:liver RGD PMID:11844796 RGD:2289670 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO
IEP		 protein:increased expression:liver:
mRNA, protein:increased expression:liver		 RGD PMID:15885882 PMID:11844796 RGD:9588598, RGD:2289670 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO
IEP		 mRNA:increased expression:liver:
mRNA, protein:increased expression:liver		 RGD PMID:15885882 PMID:11844796 RGD:9588598, RGD:2289670 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18019677 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dsn1 DSN1 component of MIS12 kinetochore complex disease_progression ISO RGD PMID:30136646 RGD:27372884 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dynlrb1 dynein light chain roadblock-type 1 ISO RGD PMID:11750132 RGD:13208527 NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:143,742,586...143,764,227 		JBrowse link
G Dynlrb2 dynein light chain roadblock-type 2 ISO RGD PMID:11750132 RGD:13208527 NCBI chr19:44,520,134...44,531,384
Ensembl chr19:44,520,134...44,531,387 		JBrowse link
G E2f1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619 PMID:15565109 PMID:28284560 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Eaf2 ELL associated factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Ect2 epithelial cell transforming 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression, increased phosphorylation:liver (human) RGD PMID:28060762 RGD:153298915 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 disease_progression ISO protein:decreased expression:liver: RGD PMID:23936443 RGD:10401793 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 severity
ameliorates		 ISO RGD PMID:34282556 PMID:34282556 RGD:155791664, RGD:155791664 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079 		JBrowse link
G Egf epidermal growth factor susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human)
associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human)		 CTD
RGD		 PMID:9029167 PMID:18167406 PMID:23790025 RGD:14695013, RGD:14695014 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9029167 PMID:11355950 RGD:126781769 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Ehd3 EH-domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:21,640,861...21,665,601
Ensembl chr 6:21,639,290...21,665,236 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:14578863 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Enah ENAH, actin regulator disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35030977 RGD:155791678 NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955 		JBrowse link
G Eng endoglin IEP protein:increased expression:liver (rat) RGD PMID:20368095 RGD:7257538 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ep300 E1A binding protein p300 IEP protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26735578 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epcam epithelial cell adhesion molecule severity ISO protein:increased expression:liver RGD PMID:24616575 RGD:14695007 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephb1 Eph receptor B1 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7892276 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epo erythropoietin disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Eps8l3 EPS8 like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:11355950 RGD:126781769 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO DNA:insertion/deletion:3'UTR:rs6147150 (human) RGD PMID:22294845 RGD:126781763 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO mRNA, protein:increased expression:liver (human) RGD PMID:15922480 RGD:155598683 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility
disease_progression		 ISO DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNPs:exon 23: p.K751Q (rs13181) (human)
DNA:SNP:cd: 312A>G (human)		 RGD PMID:19919686 PMID:25531380 PMID:28598207 PMID:28927037 RGD:25671459, RGD:25671460, RGD:25671461, RGD:150530503 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ereg epiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35776891 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Exo1 exonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility ISO mRNA:increased expression:liver (human)
DNA:SNPs: :multiple
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28284560 PMID:34545456 PMID:24211739 PMID:26517514 PMID:24040354 More... RGD:10755339, RGD:11537550, RGD:126779595, RGD:126779608 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2 coagulation factor II, thrombin severity ISO CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;protein:altered expression, altered processing:liver (human)		 CTD
RGD		 PMID:2821104 PMID:7620113 RGD:14975114 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fabp5 fatty acid binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fam180a family with sequence similarity 180, member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047 		JBrowse link
G Fam83d family with sequence similarity 83, member D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fancd2 FA complementation group D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412 		JBrowse link
G Fanci FA complementation group I ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP
ISO		 protein:increased expression:liver: RGD PMID:29634416 PMID:11274632 PMID:30737368 RGD:13792608, RGD:14700677, RGD:14700700 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand ISO protein:increased expression:liver: RGD PMID:11274632 RGD:14700677 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:15543204 PMID:21147110 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fat1 FAT atypical cadherin 1 disease_progression ISO mRNA,protein:increased expression:liver (human) RGD PMID:24590895 RGD:151347630 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22039417 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbxl18 F-box and leucine-rich repeat protein 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:11,674,538...11,701,317
Ensembl chr12:11,676,115...11,699,181 		JBrowse link
G Fbxo11 F-box protein 11 exacerbates
ameliorates		 ISO mRNA:increased expression:liver (human) RGD PMID:32657545 PMID:29518611 RGD:152025263, RGD:152025259 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase exacerbates ISO DNA:hypermethylation:promoter (human) RGD PMID:31038805 RGD:153323297 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934 		JBrowse link
G Fgf19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgf3 fibroblast growth factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:200,001,162...200,005,539
Ensembl chr 1:200,001,261...200,005,187 		JBrowse link
G Fgf4 fibroblast growth factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 treatment ISO ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156 PMID:36029209 More... RGD:25330358, RGD:25440476, RGD:25440478 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 severity ISO associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human) RGD PMID:30952770 RGD:38501096 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 treatment ISO RGD PMID:32677805 RGD:150520166 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fh fumarate hydratase ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:10896297 PMID:15221078 PMID:16876016 PMID:17182618 PMID:18313410 More... NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase IDA RGD PMID:12112319 RGD:632723 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ameliorates ISO human cells in mouse model RGD PMID:27511526 RGD:149735514 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Flvcr1 FLVCR choline and heme transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:102,586,263...102,608,647
Ensembl chr13:102,586,257...102,608,661 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029167 PMID:28284560 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO mRNA:increased expression:liver (human) RGD PMID:30086463 PMID:32048611 RGD:153344517, RGD:153344521 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxa1 forkhead box A1 susceptibility
disease_progression
sexual_dimorphism 		ISO DNA:VNTR, SNPs, haplotypes:multiple:
protein:decreased expression:liver		 RGD PMID:29208003 PMID:31400761 PMID:25965836 RGD:151665820, RGD:151665752, RGD:11054501 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxm1 forkhead box M1 ISO
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:15082532 PMID:17173139 PMID:28284560 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 ISO mRNA:decreased expression:liver RGD PMID:28972178 RGD:14401599 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxp1 forkhead box P1 treatment IEP RGD PMID:25156538 RGD:9587823 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Foxp3 forkhead box P3 ISO protein:increased expression:liver RGD PMID:21086571 RGD:38548919 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Fst follistatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203361 PMID:19363144 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Fth1 ferritin heavy chain 1 IEP mRNA:increased expression:liver (rat) RGD PMID:9054589 RGD:632698 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fubp1 far upstream element binding protein 1 exacerbates
ameliorates		 ISO mRNA:increased expression:liver (human)
human cell line in a mouse model
associated with Chronic Hepatitis C;mRNA:increased expression:liver (human)		 RGD PMID:31587040 PMID:19637194 PMID:25995247 RGD:151361188, RGD:151361194, RGD:151361196 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 treatment ISO associated with Glycogen Storage Disease IA, human gene in a mouse model RGD PMID:28096054 RGD:14695537 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase disease_progression IEP
ISO		 mRNA:increased expression:liver (human) RGD PMID:25473368 PMID:35693827 RGD:10449118, RGD:153344586 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16767786 PMID:21472284 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gba3 glucosylceramidase beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Gc GC, vitamin D binding protein susceptibility IEP
ISO		 protein:increased expression:liver
associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human)		 RGD PMID:21683810 PMID:25541958 RGD:5509919, RGD:14402025 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20512989 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdf2 growth differentiation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23936038 PMID:28284560 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 disease_progression ISO HBV associated
RNA,protein:increased expression, activity:liver:		 RGD PMID:11940314 PMID:27793641 PMID:10572675 RGD:14701040, RGD:14701041, RGD:14701048 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghr growth hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gins1 GINS complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gjb2 gap junction protein, beta 2 IDA DNA, mRNA:promoter hypermethylation, decreased expression:liver RGD PMID:17295234 RGD:2289638 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Glul glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gmnn geminin, DNA replication inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Gmps guanine monophosphate synthase IEP protein:increased activity:hepatoma (rat) RGD PMID:6861338 RGD:5135537 NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875 		JBrowse link
G Gnao1 G protein subunit alpha o1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnaz G protein subunit alpha z ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907 		JBrowse link
G Gnmt glycine N-methyltransferase ISO
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:19146867 PMID:31086990 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Golm1 golgi membrane protein 1 severity ISO protein:increased expression:serum
mRNA, protein:increased expression:liver		 RGD PMID:21140449 PMID:21443671 RGD:401827118, RGD:401827119 NCBI chr17:4,995,925...5,044,329
Ensembl chr17:4,996,104...5,034,057 		JBrowse link
G Gpc1 glypican 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpc3 glypican 3 severity
treatment
disease_progression
exacerbates		 ISO
IMP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
protein:increased expression:serum
mRNA:increased expression:Peripheral Blood (human)
mRNA,protein:increased expression:peripheral blood mononuclear cell,blood serum, liver (human)
protein:increased expression:blood serum (human)
protein:increased expression:liver (human)		 CTD
RGD		 PMID:16698587 PMID:27286460 PMID:28284560 PMID:19496787 PMID:25449037 More... RGD:243065134, RGD:14695019, RGD:14695020, RGD:14695020, RGD:243065125, RGD:243065131, RGD:243065135, RGD:243065139 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpm6a glycoprotein m6a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Gpr158 G protein-coupled receptor 158 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:83,777,625...84,244,428
Ensembl chr17:83,834,569...84,244,428 		JBrowse link
G Gpr182 G protein-coupled receptor 182 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210 		JBrowse link
G Gpx1 glutathione peroxidase 1 severity
susceptibility
no_association		 ISO associated with hepatitis C;DNA:missense mutation:CDS:p.P198L (rs1050450) (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:CDS:p.P198L (human)		 RGD PMID:26990426 PMID:16510607 PMID:19929244 PMID:25894370 RGD:11533013, RGD:151708729, RGD:152995483, RGD:152998906 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 severity
disease_progression		 ISO mRNA,protein:decreased expression:liver, blood plasma (human)
DNA:hypermethylation		 RGD PMID:25333265 PMID:25445749 PMID:27570561 RGD:151665355, RGD:151665509, RGD:401827855 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grb7 growth factor receptor bound protein 7 exacerbates ISO protein:increased expression:liver (human) RGD PMID:17634422 RGD:151347655 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility
no_association		 ISO DNA:deletion:cds (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7892276 PMID:11859714 PMID:20683151 PMID:20672314 RGD:7488953, RGD:14700951, RGD:14700979 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism
DNA:increased methylation:promoter		 CTD
RGD		 PMID:9029167 PMID:22536438 RGD:14401712 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility
no_association		 ISO DNA:deletion RGD PMID:23053942 PMID:20683151 PMID:20672314 RGD:14401714, RGD:14700951, RGD:14700979 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gys2 glycogen synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G H19 H19 imprinted maternally expressed transcript IEP mRNA:increased expression:liver RGD PMID:17393425 RGD:2306187 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hamp hepcidin antimicrobial peptide ISO
IEP
IDA		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver (human)
DNA:hypermethylation,hypomethylation:promoter		 CTD
RGD		 PMID:28284560 PMID:29235098 PMID:29235098 RGD:15042879, RGD:15042879 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hao2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 disease_progression ISO associated with hepatitis B;DNA:SNP: : ���1516 G>T (human) RGD PMID:27034168 RGD:40818257 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hdac2 histone deacetylase 2 disease_progression ISO mRNA:increased expression:liver: RGD PMID:24448241 RGD:9590206 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac4 histone deacetylase 4 ISO mRNA:increased expression:liver: RGD PMID:21837748 RGD:9681451 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hfe homeostatic iron regulator disease_progression ISO associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:20019189 PMID:29642405 RGD:2317357, RGD:14746967 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9932610 PMID:11896611 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hgfac HGF activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278 		JBrowse link
G Hhip Hedgehog-interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18559595 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment
disease_progression		 IMP
ISO		 protein:increased expression:liver (human) RGD PMID:19335982 PMID:26078356 PMID:31321740 RGD:9068886, RGD:11526468, RGD:155882550 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated disease_progression ISO mRNA, protein:increased expression:liver (human)
human cells in mouse model
mRNA:increased expression:liver (human)		 RGD PMID:31142329 PMID:31142329 PMID:30205391 PMID:35693827 RGD:153344574, RGD:153344574, RGD:153344577, RGD:153344586 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hjurp Holliday junction recognition protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728 		JBrowse link
G Hmgb2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20851854 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9207284 PMID:21147110 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 disease_progression ISO RGD PMID:28867541 RGD:14975299 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hnf1a HNF1 homeobox A treatment IMP human cell line in mouse model RGD PMID:29466992 RGD:14700664 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEP
ISO		 protein:decreased expression:liver: RGD PMID:20876809 PMID:20876809 RGD:12904747, RGD:12904747 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO
IEP		 protein:increased expression:liver (human)
mRNA:increased expression:liver (rat)		 RGD PMID:20604928 PMID:23633480 RGD:9685422, RGD:9685423 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B severity ISO mRNA:increased expression:liver (human) RGD PMID:24638979 RGD:10059322 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D ISO
IEP		 protein:increased expression:liver (human)
protein:increased expression:liver (rat)		 RGD PMID:20102719 PMID:22318685 RGD:10042969, RGD:10042977 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L ISO associated with Hepatitis B RGD PMID:24125732 RGD:9999429 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Hoxa10 homeobox A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:81,331,591...81,340,878
Ensembl chr 4:81,331,591...81,340,919 		JBrowse link
G Hoxa13 homeo box A13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Hoxd9 homeo box D9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:59,600,575...59,602,755
Ensembl chr 3:59,600,575...59,602,754 		JBrowse link
G Hp haptoglobin ISO protein:increased expression:saliva
protein:decreased expression:liver (human)		 RGD PMID:31041878 PMID:24259486 RGD:27095881, RGD:152995276 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IEP protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hras HRas proto-oncogene, GTPase treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
human cells in a mouse model
human plasmid in a mouse model
mRNA:increased expression:liver (mouse)
ClinVar Annotator: match by term: Hepatocellular cancer		 CTD
ClinVar
RGD		 PMID:8200073 PMID:9311599 PMID:11150980 PMID:12835555 PMID:16155195 More... RGD:14688054, RGD:14688055, RGD:14694809, RGD:14694810 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 PMID:29698666 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16799960 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Htra1 HtrA serine peptidase 1 exacerbates
disease_progression		 ISO protein:decreased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:20943460 PMID:26403966 RGD:152985524, RGD:152985529 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam1 intercellular adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:26109813 RGD:11056752 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular cancer		 CTD
ClinVar		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar
RGD		 PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 More... RGD:14985249 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ier2 immediate early response 2 ISO mRNA, protein:decreased expression:liver (human) RGD PMID:32009420 RGD:153323326 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
G Ifna1 interferon, alpha 1 susceptibility ISO CTD Direct Evidence: therapeutic
associated with hepatitis B; DNA:SNP:: ( rs1831583) (human)		 CTD
RGD		 PMID:17088986 PMID:17971768 PMID:18665156 PMID:29080269 RGD:21406429 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifng interferon gamma ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifnl1 interferon, lambda 1 ameliorates ISO human protein and cells in mouse model RGD PMID:24769671 RGD:126848750 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21339737 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs, haplotype: :		 CTD
RGD		 PMID:17441810 PMID:23958494 PMID:24758241 RGD:14985227 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 susceptibility IEP
ISO		 CTD Direct Evidence: marker/mechanism
associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human)		 CTD
RGD		 PMID:12532445 PMID:16092956 PMID:17554210 PMID:16750516 RGD:2311523, RGD:14401723 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:80,908,300...80,951,097
Ensembl chr10:80,908,076...80,951,129 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor disease_progression
no_association
treatment		 ISO DNA:mutation:G1449V (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:
DNA:loss of heterozygosity:liver
DNA:loss of heterozygosity,mutations:liver:
associated with hepatitis B virus; mRNA:decreased expression:liver:
ClinVar Annotator: match by term: Hepatocellular carcinoma		 OMIM
CTD
ClinVar
RGD		 PMID:9722161 PMID:15057872 PMID:25741868 PMID:7493029 PMID:29940770 More... RGD:1624323, RGD:14985218, RGD:14985219, RGD:14985220, RGD:14985221, RGD:14985222, RGD:14985225 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment ISO protein:decreased expression:liver (human) RGD PMID:29551768 PMID:22176836 PMID:25173965 PMID:17292824 PMID:24971483 More... RGD:153297807, RGD:153297813, RGD:153305943, RGD:153305945, RGD:11079569, RGD:153305947 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ameliorates ISO protein:increased expression:liver (human) RGD PMID:25301737 RGD:150540326 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Il10 interleukin 10 treatment IDA
ISO		 RGD PMID:23822114 PMID:26890368 RGD:7365006, RGD:14975171 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A susceptibility ISO associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human)		 RGD PMID:27819525 PMID:20521253 PMID:26631030 RGD:25440490, RGD:25440491, RGD:25440501 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il18 interleukin 18 severity
disease_progression
susceptibility		 ISO associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)
DNA:SNP:promoter:-137G>C(rs187238)(human)
associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)		 RGD PMID:29341496 PMID:26893476 PMID:27429592 PMID:27470888 RGD:14695526, RGD:11538094, RGD:14695540, RGD:14696663 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO mRNA:decreased expression:liver RGD PMID:26893476 PMID:26893476 RGD:11538094, RGD:11538094 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism:promoter:-31T>C (human) RGD PMID:21653279 RGD:7401222 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:10933975 PMID:9449371 RGD:8693323, RGD:14747035 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il21 interleukin 21 ISO associated with hepatitis B;DNA:SNPS, haplotype:(rs13143866, rs2221903, rs907715) (human) RGD PMID:25892873 RGD:127285359 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il6 interleukin 6 treatment
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2069852 (human)
mRNA,protein:increased expression:liver, blood serum (mouse)		 CTD
RGD		 PMID:17615358 PMID:20818158 PMID:26297436 PMID:27022031 PMID:27368337 More... RGD:14975289, RGD:11344640 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer IEP RGD PMID:15780071 RGD:1626706 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Ing3 inhibitor of growth family, member 3 treatment IDA RGD PMID:25156538 RGD:9587823 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715 		JBrowse link
G Inmt indolethylamine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Ins1 insulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 ISO associated with Chronic Hepatitis C;mRNA:decreased expression:liver (human) RGD PMID:33132693 RGD:150340613 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor IEP
IMP		 mRNA, protein:increased expression:liver (human, rat)
human cells in a mouse model		 RGD PMID:23633480 PMID:29610518 RGD:9685423, RGD:14700930 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20977743 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 ISO
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:20977743 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Irf2 interferon regulatory factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024 		JBrowse link
G Irs1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1311924 PMID:23958494 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16127164 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier ISO CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 disease_progression ISO associated with hepatitis B;protein:decreased expression:serum RGD PMID:24836184 RGD:40903002 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO protein:increased expression:liver RGD PMID:30660174 RGD:14694832 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jak1 Janus kinase 1 ISO RGD PMID:23788652 RGD:150524353 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 severity
exacerbates
ameliorates
treatment		 IEP
ISO		 mRNA:decreased expression:liver (human)
protein:increased phosphorylation:liver (human)
protein:increased phosphorylation:liver (mouse)
associated with Diseases of the Aged and non-alcoholic fatty liver disease
L-JAK2 KO		 RGD PMID:25420511 PMID:22392353 PMID:22821478 PMID:31393852 PMID:28100771 More... RGD:18182928, RGD:125097525, RGD:127285621, RGD:127285655, RGD:127285675, RGD:127285672 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jdp2 Jun dimerization protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO associated with HBV;protein:increased expression:liver (human) RGD PMID:15927205 RGD:153297768 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO protein:decreased expression:liver (human) RGD PMID:23643089 RGD:9590314 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:liver (human) RGD PMID:17022810 RGD:9693723 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kdm1a lysine demethylase 1A severity ISO mRNA, protein:increased expression:liver (human) RGD PMID:23236241 RGD:9681002 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm3a lysine demethylase 3A ISO mRNA:increased expression:liver (human) RGD PMID:21607773 RGD:9590222 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdm5c lysine demethylase 5C exacerbates ISO protein:increased expression:liver (human) RGD PMID:26503415 RGD:11530160 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870 		JBrowse link
G Kdm6a lysine demethylase 6A ameliorates ISO human cells in a mouse model RGD PMID:32765772 RGD:150429729 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kdm8 lysine demethylase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841 		JBrowse link
G Kdr kinase insert domain receptor treatment
disease_progression		 ISO DNA:SNPs: :rs1870377, rs2071559, rs2305948 (human)
protein:increased expression:liver
protein:decreased expression:liver
associated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human)		 RGD PMID:25182707 PMID:19177438 PMID:25333267 PMID:23660204 PMID:24445728 RGD:126848806, RGD:126848810, RGD:126848812, RGD:126848813, RGD:126848814 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kif11 kinesin family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif14 kinesin family member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164 		JBrowse link
G Kif15 kinesin family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750 		JBrowse link
G Kif18a kinesin family member 18A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kif18b kinesin family member 18B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850 		JBrowse link
G Kif1b kinesin family member 1B severity
susceptibility		 ISO mRNA, protein:decreased expression:liver (human)
DNA:snp:intron:c.2537+518A>G (rs17401966) (human)		 RGD PMID:26217094 PMID:27122668 RGD:11052488, RGD:12738461 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Kif20a kinesin family member 20A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif23 kinesin family member 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Kif2c kinesin family member 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Kif4a kinesin family member 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:65,721,746...65,824,277
Ensembl chr  X:65,721,779...65,824,139 		JBrowse link
G Kifc1 kinesin family member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Klf4 KLF transcription factor 4 disease_progression
treatment		 ISO RGD PMID:22677193 PMID:22677193 RGD:14402023, RGD:14402023 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klrb1 killer cell lectin like receptor B1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 4:162,456,294...162,474,989
Ensembl chr 4:162,456,294...162,474,989 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kmt2b lysine methyltransferase 2B ISO DNA:insertions, translocations:intron:IVS3, multiple (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22634754 PMID:18320596 RGD:9588597 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kras KRAS proto-oncogene, GTPase induced ISO
IAGP		 CTD Direct Evidence: marker/mechanism
aflatoxin B1 induced:DNA:transversion,transition mutations:cds:
mRNA,protein:increased expression:liver
ClinVar Annotator: match by term: Hepatocellular cancer		 CTD
ClinVar
RGD		 PMID:2278970 PMID:3122217 PMID:11286481 PMID:11563603 PMID:12460918 More... RGD:11568697, RGD:14398750 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt18 keratin 18 ISS OMIM:114550 MouseDO NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Lcat lecithin cholesterol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ameliorates ISO protein:increased expression:blood serum (mouse)
protein:increased expression:blood serum (human)
human cells in mouse model		 RGD PMID:24892551 PMID:24892551 PMID:21394108 RGD:153323333, RGD:153323333, RGD:153323335 NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983 		JBrowse link
G Lep leptin susceptibility
severity		 IAGP
IEP		 DNA:SNP:enhancer:-2548G>A (rs7799039) (human)
protein:increased expression:liver (human)		 RGD PMID:28452232 PMID:18573568 RGD:15039399, RGD:25330348 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNPs:cds:p.Gln223Arg, Lys109Arg (human) RGD PMID:23090836 RGD:21079466 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904 		JBrowse link
G Lifr LIF receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Lilrb3 leukocyte immunoglobulin like receptor B3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:69,928,948...69,939,461
Ensembl chr 1:69,928,945...69,939,048 		JBrowse link
G Loxl3 lysyl oxidase-like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IDA RGD PMID:19000703 RGD:2317680 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lrat lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Lrp1b LDL receptor related protein 1B exacerbates ISO protein:increased expression:liver (human)
DNA:mutations:multiple: (human)		 RGD PMID:33324588 PMID:33391418 RGD:150429776, RGD:150429785 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:78,239,900...78,406,490 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309 		JBrowse link
G Lztr1 leucine zipper like post translational regulator 1 ISO DNA:missense mutation:cds, liver (human) RGD PMID:28622513 RGD:151893487 NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Magec2 MAGE family member C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:140,610,610...140,615,484
Ensembl chr  X:140,606,825...140,615,471 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 exacerbates ISO
IEP		 mRNA:increased expression:liver (human)
protein:increased expression:liver, cytosol (rat)		 RGD PMID:33553243 PMID:9397988 RGD:150530475, RGD:150530477 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO protein:decreased expression:liver (human) RGD PMID:32850377 RGD:150429765 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 exacerbates ISO mRNA:decreased expression:liver (human) RGD PMID:31310010 RGD:150573714 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO RGD PMID:26560698 RGD:11342977 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
severity
treatment		 ISO human cell line in a mouse model
human recombinant gene and cell line in a mouse model		 RGD PMID:21196414 PMID:27010469 PMID:31922225 RGD:151347673, RGD:151347674, RGD:151347839 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO protein:increased expression:liver RGD PMID:27468214 RGD:401976278 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 treatment
exacerbates		 ISO RGD PMID:25216638 PMID:23271722 RGD:151665347, RGD:151665348 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ameliorates ISO protein:decreased phosphorylation:liver (human) RGD PMID:33875785 RGD:150340688 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapt microtubule-associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Marco macrophage receptor with collagenous structure ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521 		JBrowse link
G Mat1a methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12060674 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mbl2 mannose binding lectin 2 severity
susceptibility
no_association		 ISO associated with hepatitis C;DNA:SNP: :221C>G(rs709620)(human)
associated with hepatitis B-related cirrhosis;DNA:SNP: :rs11003123(G>A)(human)
associated with viral hepatitis;DNA:polymorphisms:exon:
DNA:SNPs:promoter:rs7096206(human)
protein:decreased expression:plasma
associated with hepatitis B;DNA:SNP:exon:		 RGD PMID:21733090 PMID:27298104 PMID:18221301 PMID:25787238 PMID:27557564 More... RGD:14696813, RGD:14696814, RGD:14696829, RGD:14696833, RGD:14696835, RGD:14696836 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr  X:37,410,914...37,461,130
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 susceptibility IAGP
IEP		 associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human)
associated with hepatitis B;miRNA:increased expression:liver (human)		 RGD PMID:24416400 PMID:27298561 RGD:15042885, RGD:15042853 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor ISS OMIM:114550 MouseDO NCBI chr20:32,818,219...32,929,577
Ensembl chr20:32,844,951...32,929,600 		JBrowse link
G Mdm2 MDM2 proto-oncogene susceptibility ISO DNA:transversion:promoter:g.-309T>G (human) RGD PMID:20019189 RGD:2317357 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Me1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mecp2 methyl CpG binding protein 2 ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver		 CTD
RGD		 PMID:26189965 PMID:11844796 RGD:2289670 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Med1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20007298 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Melk maternal embryonic leucine zipper kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity
susceptibility		 IEP
ISO		 protein:increased expression:liver (rat)
mRNA:increased expression:liver, carcinoma (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma		 CTD
ClinVar
OMIM
RGD		 PMID:21774103 PMID:21970370 PMID:22703879 PMID:24728327 PMID:25741868 More... RGD:2317495, RGD:2317575, RGD:1600123, RGD:152995524, RGD:152995524 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Mill1 MHC I like leukocyte 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21499248 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Mir106b microRNA 106b disease_progression
severity		 IEP miRNA:decreased expression:liver (human)
miRNA:increased expression:plasma (human)
miRNA:increased expression:serum (human)
miRNA:increased expression:liver (human)		 RGD PMID:28958640 PMID:25894380 PMID:28611524 PMID:31406464 RGD:15042874, RGD:15042875, RGD:15042876, RGD:15042877 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425 		JBrowse link
G Mir107 microRNA 107 treatment
onset		 ISO RNA:decreased expression:liver:
RNA:increased expression:liver:		 RGD PMID:30738047 PMID:27773820 PMID:26191213 PMID:28079796 RGD:14975277, RGD:14975278, RGD:11066920, RGD:14975300 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir122 microRNA 122 severity ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B miRNA:decreased expression:liver
protein:decreased expression:liver (human)
mRNA:decreased expression:blood (human)		 CTD
RGD		 PMID:16924677 PMID:25269820 PMID:25422324 PMID:19584283 PMID:27528885 RGD:14394424, RGD:14401603, RGD:151356981, RGD:151361113 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir125a microRNA 125a treatment
severity		 ISO RNA:increased expression:liver: RGD PMID:30257386 PMID:30257386 PMID:29951066 RGD:21403677, RGD:21403677, RGD:21403679 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir127 microRNA 127 ISO miRNA:decreased expression:liver (human) RGD PMID:24854842 RGD:152995355 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir130b microRNA 130b severity ISO miRNA:increased expression:liver RGD PMID:25387077 RGD:14694845 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir133a1 microRNA 133a-1 disease_progression ISO mRNA:decreased expression:liver (human)
human cells in mouse model		 RGD PMID:30086463 PMID:30086463 RGD:153344517, RGD:153344517 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir133b microRNA 133b severity ISO mRNA:decreased expression:liver(human) RGD PMID:30391496 RGD:155804298 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217 		JBrowse link
G Mir136 microRNA 136 exacerbates ISO RNA:decreased expression:liver (human) RGD PMID:28849100 RGD:153345547 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir139 microRNA 139 ISO RNA:decreased expression:liver (human) RGD PMID:30710422 RGD:153344549 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902 		JBrowse link
G Mir145 microRNA 145 severity IEP miRNA:decreased expression:liver (human) RGD PMID:30572504 RGD:15039395 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir146a microRNA 146a sexual_dimorphism
susceptibility		 ISO associated with hepatitis B;miRNA:SNP:exon: (rs2910164) (human)
miRNA:SNP: (human)
associated with hepatitis B;miRNA:SNP: (human)		 RGD PMID:18711148 PMID:24816919 PMID:24615520 RGD:126925148, RGD:126925158, RGD:126925187 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir150 microRNA 150 ISO mRNA:decreased expression:liver (human) RGD PMID:30205391 RGD:153344577 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mir152 microRNA 152 disease_progression ISO miRNA:decreased expression:liver RGD PMID:30967300 PMID:26531720 RGD:19165146, RGD:21066331 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir154 microRNA 154 ISO RNA:decreased expression:liver (human) RGD PMID:33195697 RGD:152995478 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir155 microRNA 155 disease_progression ISO miRNA:decreased expression:peripheral blood mononuclear cell
miRNA:increased expression:serum
associated with hepatitis C;DNA:SNP: :rs767649 (human)		 RGD PMID:27035278 PMID:27035278 PMID:28074870 PMID:30710754 PMID:29528577 More... RGD:21079433, RGD:21079433, RGD:21079477, RGD:21081523, RGD:24922222, RGD:25671465 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir181c microRNA 181c IEP miRNA:decreased expression:liver (human) RGD PMID:31114379 RGD:15042894 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir18a microRNA 18a severity IEP miRNA:increased expression:liver (human)
associated with hepatitis B;miRNA:increased expression:liver (human)
associated with Hepatitis C, Chronic;miRNA:increased expression:serum (human)		 RGD PMID:19027010 PMID:30519035 PMID:30191950 PMID:24975878 PMID:29455432 RGD:15039398, RGD:15039400, RGD:15039389, RGD:15039401, RGD:15039404 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir193a microRNA 193a disease_progression
exacerbates		 ISO miRNA:decreased expression:liver (human)
RNA:increased expression:blood serum (human)
DNA:hypomethylation		 RGD PMID:26263159 PMID:30710422 PMID:32960907 PMID:28036298 RGD:11070076, RGD:153344549, RGD:153344563, RGD:153344564 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir195 microRNA 195 severity IEP
IMP		 miRNA:decreased expression:liver (human)
miRNA:decreased expression:liver (mouse)		 RGD PMID:25607636 PMID:25607636 RGD:15042896, RGD:15042896 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir196a microRNA 196a susceptibility ISO DNA:SNP: : (rs11614913)
associated with hepatitis B, chronic; DNA:SNP: : (rs12304647)		 RGD PMID:21692953 PMID:24248733 RGD:14401594 RGD:14401595 NCBI chr 7:134,110,400...134,110,509
Ensembl chr 7:134,110,400...134,110,509 		JBrowse link
G Mir200b microRNA 200b treatment
disease_progression		 ISO mRNA:decreased expression:liver
DNA:hypermethylation:promoter		 RGD PMID:26919246 PMID:26919246 PMID:28383782 PMID:28383782 PMID:28383782 RGD:14928318, RGD:14928318, RGD:14928322, RGD:14928322, RGD:14928322 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir20a microRNA 20a ISO associated with Human Viral Hepatitis RGD PMID:30623908 RGD:25823145 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 severity
treatment		 ISO miRNA:increased expression:liver RGD PMID:20447717 PMID:24963487 PMID:21749846 RGD:14695022, RGD:40925952, RGD:41404642 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir212 microRNA 212 disease_progression
ameliorates		 ISO RGD PMID:25965836 PMID:25965836 RGD:11054501, RGD:11054501 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir22 microRNA 22 severity
disease_progression		 ISO in male; RNA:increased expression:liver: RGD PMID:23766411 PMID:27811373 PMID:21750200 RGD:14700874, RGD:14700875, RGD:14700876 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir221 microRNA 221 disease_progression
treatment		 ISO
IEP		 RGD PMID:25817558 PMID:29713162 PMID:29713162 PMID:22009537 PMID:28096271 More... RGD:11086123, RGD:18337267, RGD:18337267, RGD:18337273, RGD:18337275, RGD:18337275, RGD:18337275, RGD:151893509 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 disease_progression
severity		 ISO RGD PMID:24124720 PMID:20103675 RGD:151709003, RGD:151709004 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir223 microRNA 223 disease_progression ISO associated with high-fat diet,
associated with Chronic HepatitisC; RNA:decreased expression:serum:
associated with Chronic Hepatitis B; RNA:decreased expression:serum:
RNA:increased expression:serum:		 RGD PMID:30964207 PMID:28982915 PMID:25391771 PMID:24595450 PMID:21229610 RGD:21408549, RGD:21408578, RGD:21408580, RGD:21408583, RGD:21408591 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir224 microRNA 224 severity IEP miRNA:increased expression:liver (human)
associated with hepatitis B;miRNA:increased expression:liver (human)
miRNA:increased expression:plasma (human)		 RGD PMID:23922662 PMID:22459148 PMID:23913306 PMID:24923856 PMID:27462777 RGD:18182921, RGD:18182922, RGD:18182923, RGD:18182924, RGD:18182926 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169 		JBrowse link
G Mir23a microRNA 23a ISO miRNA:increased expression:liver RGD PMID:22318941 RGD:14694846 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir23b microRNA 23b ISO DNA:hypermethylation RGD PMID:28036298 RGD:153344564 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir25 microRNA 25 severity IEP miRNA:increased expression:liver (human)
associated with hepatitis B;miRNA:increased expression:serum (human)
associated with hepatitis B;miRNA:increased expression:liver (human)		 RGD PMID:30191950 PMID:24593846 PMID:21098710 PMID:27298561 RGD:15039389, RGD:15042897, RGD:15042899, RGD:15042853 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015 		JBrowse link
G Mir27a microRNA 27a severity
treatment		 ISO human cell line in a mouse model
human miRNA and cell line in a mouse model		 RGD PMID:29143999 PMID:30083261 RGD:14696659, RGD:14696660 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir29a microRNA 29a severity ISO associated with hepatitis B;miRNA:increased expression:liver (human) RGD PMID:23285022 RGD:15042850 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir31 microRNA 31 severity ISO
IEP		 RNA:decreased expression:liver (human)
miRNA:decreased expression:liver (human)
miRNA:decreased expression:liver (rat)		 RGD PMID:28623129 PMID:25797269 PMID:25797269 RGD:152998991, RGD:11085965, RGD:11085965 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir340-1 microRNA 340-1 ISO miRNA:decreased expression:liver RGD PMID:27998770 RGD:18936991 NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665 		JBrowse link
G Mir34a microRNA 34a treatment ISO human cell line in a mouse model
miRNA:decreased expression:liver		 RGD PMID:25217526 PMID:29328457 RGD:14694835, RGD:14694836 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir411 microRNA 411 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:30086881 RGD:152999437 NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279 		JBrowse link
G Mir455 microRNA 455 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35286011 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
G Mir494 microRNA 494 disease_progression ISO RGD PMID:25820676 RGD:155900754 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir615 microRNA 615 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22819824 NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978 		JBrowse link
G Mir665 microRNA 665 disease_progression ISO mRNA:increased expression:liver (human)
associated with metastasis; human cells in mouse model		 RGD PMID:30237408 PMID:30237408 RGD:151361293, RGD:151361293 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir93 microRNA 93 severity IEP associated with hepatitis B;miRNA:increased expression:liver (human) RGD PMID:27298561 PMID:28592130 RGD:15042853, RGD:15042900 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir96 microRNA 96 severity IEP miRNA:increased expression:liver (human) RGD PMID:28892647 PMID:25813403 RGD:15042901, RGD:15042902 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 ISO miRNA:decreased expression:liver RGD PMID:22289550 RGD:14695021 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mki67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlxipl MLX interacting protein-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Mme membrane metallo-endopeptidase IEP RGD PMID:8302012 RGD:13801035 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20084675 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20084675 PMID:21681821 RGD:8547864 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor ISO human cells in mouse model RGD PMID:23157389 RGD:126925755 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797 		JBrowse link
G Mpo myeloperoxidase susceptibility
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human)
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human)		 CTD
RGD		 PMID:19731237 PMID:19731237 PMID:21907168 RGD:26923907, RGD:27095879 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mro maestro ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044 		JBrowse link
G Msh3 mutS homolog 3 ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:28492532 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh5 mutS homolog 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I IAGP RGD PMID:2548155 RGD:2302301 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 IEP mRNA:increased expression:liver RGD PMID:2507335 RGD:2302316 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565 		JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17363595 PMID:19363144 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17363595 PMID:28284560 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtbp MDM2 binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29765550 NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827 		JBrowse link
G Mtdh metadherin treatment ISO human cells in a mouse model RGD PMID:26351209 RGD:11096879 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase IEP mRNA:increased expression:liver RGD PMID:3878730 RGD:2302305 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
disease_progression
onset		 ISO DNA:SNP,haplotype: :677C>T, 1298A>C(human)
DNA:SNP: :677C>T(human)
DNA:SNP: :1298A>C(human)
DNA:SNPs: :677C>T, 1298A>C(human)		 RGD PMID:17503006 PMID:23996892 PMID:19035314 PMID:17659576 RGD:14696703, RGD:14696704, RGD:14696707, RGD:14696708 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtor mechanistic target of rapamycin kinase severity ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human)		 CTD
RGD		 PMID:21147110 PMID:25371154 RGD:152995471 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:SNP: :66A>G(human) RGD PMID:19035314 RGD:14696707 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Mug2 murinoglobulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475 		JBrowse link
G Mvk mevalonate kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment
severity		 ISO
IDA
IEP		 mRNA:increased expression:liver (rat)
mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9029167 PMID:12029619 PMID:15565109 PMID:29698666 PMID:21644509 More... RGD:6903288, RGD:7240567, RGD:7240695, RGD:7241004 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor exacerbates
ameliorates
treatment		 ISO
IEP		 mRNA:increased expression:liver (human)
protein, mRNA:decreased expression:liver (human)
human cell line in a mouse model
protein:increased expression:liver (human)
mouse cell line in a mouse model
human gene and cell in a mouse model		 RGD PMID:29022910 PMID:28370778 PMID:17615358 PMID:33575076 PMID:32144747 More... RGD:150520022, RGD:150520169, RGD:150521532, RGD:150521534, RGD:150524327, RGD:150524329, RGD:150524330, RGD:150524334, RGD:150530285 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nbn nibrin ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More... NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 exacerbates ISO RGD PMID:28273073 PMID:22556267 RGD:153002573, RGD:153002576 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ndc80 NDC80 kinetochore complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Neil3 nei-like DNA glycosylase 3 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527 		JBrowse link
G Nek2 NIMA-related kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression ISO DNA, protein:SNP, increased expression:intron, liver
protein:decreased expression:liver		 RGD PMID:29130106 PMID:27289045 PMID:26443326 RGD:150530489, RGD:150530504, RGD:11076529 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 ISS OMIM:114550 MouseDO NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular carcinoma		 CTD
ClinVar
RGD		 PMID:22561517 PMID:26619011 PMID:29018201 PMID:31546024 RGD:21201310 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 disease_progression
treatment		 ISO
IEP		 associated with Chronic Hepatitis B;DNA:insertion/deletion:3'utr: -94ins/delATTG (rs28720239) (human) RGD PMID:19797428 PMID:25999787 RGD:40400751, RGD:152177911 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha disease_progression
susceptibility		 ISO CTD Direct Evidence: therapeutic
associated with Chronic Hepatitis B;DNA:SNPs,haplotype:3'utr,promoter: 826C>T,881A>G (rs2233406,rs3138053) (human)
associated with hepatitis B;DNA:SNP:promoter:-826C>T (rs2233406) (human)		 CTD
RGD		 PMID:22022477 PMID:19797428 PMID:25223483 RGD:40400751, RGD:40902986 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx3-1 NK3 homeobox 1 treatment ISO mRNA:decreased expression:liver
human gene in a mouse model		 RGD PMID:28972178 PMID:28972178 RGD:14401599, RGD:14401599 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30081150 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO protein:increased expression:liver RGD PMID:27338800 RGD:15003194 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nnmt nicotinamide N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Nos2 nitric oxide synthase 2 treatment IEP RGD PMID:25999787 RGD:152177911 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23811326 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO
ISS		 CTD Direct Evidence: marker/mechanism
mRNA:splice variant(s):liver (human)
intestinally expressed human gene in mouse model
OMIM:114550		 CTD
MouseDO
RGD		 PMID:23811326 PMID:25496033 PMID:23811326 PMID:23213087 PMID:24954587 RGD:14696796, RGD:14928330, RGD:14928334 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nras NRAS proto-oncogene, GTPase disease_progression
severity		 ISO human gene in mouse model
mRNA, protein:increased expression:liver (mouse, human)
ClinVar Annotator: match by term: Hepatocellular cancer		 ClinVar
RGD		 PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... RGD:14696775, RGD:14696793 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Nrg1 neuregulin 1 disease_progression ISO associated with hepatitis C;mRNA:altered expression:liver (human
mRNA:increased expression:liver (human)		 RGD PMID:17393520 PMID:27514687 RGD:39456104, RGD:39456110 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 disease_progression ISO protein:decreased expression:liver RGD PMID:25333267 RGD:126848812 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex treatment
disease_progression		 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:30653265 PMID:31933938 RGD:28867240, RGD:28912742 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Oit3 oncoprotein induced transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:27,390,113...27,410,692
Ensembl chr20:27,390,113...27,410,692 		JBrowse link
G Olfml2a olfactomedin-like 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909 		JBrowse link
G Olfml2b olfactomedin-like 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607 		JBrowse link
G Orc1 origin recognition complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Otc ornithine transcarbamylase severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 disease_progression ISO mRNA,protein:decreased expression:liver: RGD PMID:21569763 RGD:12790589 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606 		JBrowse link
G Park7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18695907 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pbk PDZ binding kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pclaf PCNA clamp associated factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994 		JBrowse link
G Pcna proliferating cell nuclear antigen treatment IEP protein:increased expression:liver: RGD PMID:23219601 PMID:25999787 RGD:10448993, RGD:152177911 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdcd1 programmed cell death 1 disease_progression ISO associated with hepatitis B;DNA:SNP: : +8669 A>G (human) RGD PMID:27034168 PMID:21912640 RGD:40818257, RGD:41410800 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20506153 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like ISO ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:7898930 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28003426 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase IEP protein:increased activity:hepatoma (rat) RGD PMID:6722784 RGD:5135276 NCBI chr10:53,690,301...53,711,811
Ensembl chr10:53,691,626...53,708,420 		JBrowse link
G Pfn2 profilin 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938 		JBrowse link
G Pgd phosphogluconate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Phb1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phf6 PHD finger protein 6 exacerbates ISO mRNA:increased expression:liver (human) RGD PMID:31329335 PMID:30888215 RGD:155260288, RGD:155260308 NCBI chr  X:132,656,658...132,699,720
Ensembl chr  X:132,656,672...132,699,127 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha severity
no_association
susceptibility
treatment		 ISO
IEP		 DNA:mutations:exons:
DNA:mutation:exon:
DNA:SNPs: :rs17849071,rs17849079(human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma		 OMIM
CTD
ClinVar
RGD		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... RGD:2290476, RGD:14402404, RGD:14402405, RGD:11556371, RGD:152177911 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta treatment IEP RGD PMID:25999787 RGD:152177911 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 treatment IEP RGD PMID:31801250 PMID:25999787 RGD:151893509, RGD:152177911 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 treatment IEP RGD PMID:25999787 RGD:152177911 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 treatment IEP RGD PMID:25999787 RGD:152177911 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 disease_progression ISO associated with Chronic Hepatitis B; DNA:SNP::rs1469557(human) RGD PMID:27221889 RGD:152977752 NCBI chr15:38,097,896...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pitpnm3 PITPNM family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:56,674,697...56,766,552
Ensembl chr10:56,676,261...56,766,584 		JBrowse link
G Pitx1 paired-like homeodomain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Pkm pyruvate kinase M1/2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995 		JBrowse link
G Pkp1 plakophilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465 		JBrowse link
G Plac8 placenta associated 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates ISO human cell line in a mouse model RGD PMID:30623526 RGD:151356937 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plk1 polo-like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk4 polo-like kinase 4 sexual_dimorphism ISO DNA:hypermethylation:promoter RGD PMID:21324136 PMID:21324136 RGD:27226690, RGD:27226690 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 treatment ISO mRNA, protein:increased expression:liver (human) RGD PMID:29059470 PMID:29059470 RGD:155791679, RGD:155791679 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
G Plvap plasmalemma vesicle associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301 		JBrowse link
G Plxdc1 plexin domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:82,922,499...82,982,124
Ensembl chr10:82,922,508...82,982,130 		JBrowse link
G Pml PML nuclear body scaffold disease_progression
exacerbates
ameliorates		 ISO protein:increased expression:liver (human)
associated with hepatitis C
mRNA:increased expression:liver (mouse)		 RGD PMID:11511788 PMID:31144474 PMID:26118777 RGD:41404685, RGD:41404687, RGD:41404690 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:21319195 RGD:14981585 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit susceptibility IAGP DNA:SNPs:introns: (rs1061316, rs758130) (human) RGD PMID:28457473 RGD:15039387 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Pon1 paraoxonase 1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pot1 protection of telomeres 1 disease_progression ISO associated with hepatitis B;DNA:SNP: :rs7784168(human) RGD PMID:23907815 RGD:152975963 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility IAGP associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) RGD PMID:19119483 RGD:15042881 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma severity ISO CTD Direct Evidence: therapeutic
protein:decreased expression:liver		 CTD
RGD		 PMID:16374840 PMID:27451128 RGD:14694822 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144 		JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15010824 NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A onset IEP protein:increased expression:liver (rat) RGD PMID:20935162 RGD:10002734 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B severity ISO mRNA, protein:decreased expression:liver (human) RGD PMID:23591196 RGD:10043803 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ppp4r3c protein phosphatase 4 regulatory subunit 3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:53,630,250...53,722,658 JBrowse link
G Prc1 protein regulator of cytokinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prdm1 PR/SET domain 1 disease_progression ISO associated with hepatitis B;
associated with hepatitis B;DNA:SNP: :rs1010273(human)		 RGD PMID:31100710 PMID:31376415 RGD:150530465, RGD:150530466 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 exacerbates ISO mRNA:increased expression:liver (human)
protein:increased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:25151370 PMID:28205209 PMID:28000796 PMID:31776854 RGD:151665185, RGD:151665186, RGD:151665188, RGD:151665343 NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase severity ISO protein:decreased expression:liver (human) RGD PMID:28862485 RGD:13432206 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prl prolactin onset ISO protein:increased expression:serum (human) RGD PMID:22392353 RGD:125097525 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prom1 prominin 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527 		JBrowse link
G Ptch1 patched 1 severity
disease_progression		 ISO RGD PMID:18538319 PMID:22911366 RGD:150523837, RGD:150523842 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Pten phosphatase and tensin homolog exacerbates
treatment
severity		 ISO
IEP
ISS		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver (human)
associated with hepatitis B;protein:decreased expression:liver (human)
associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human)
OMIM:114550		 CTD
MouseDO
RGD		 PMID:27022031 PMID:12673720 PMID:30690477 PMID:12115563 PMID:31801250 More... RGD:127285591, RGD:127285603, RGD:127285610, RGD:151893509, RGD:152995524, RGD:152995524 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
treatment		 IEP
ISO		 CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter:-1195A>G (rs689466) (human)
mRNA,protein:decreased expression:liver
protein:increased expression:liver, cytosol		 CTD
RGD		 PMID:11872629 PMID:12024111 PMID:14563831 PMID:16374840 PMID:17510421 More... RGD:2300283, RGD:14695010, RGD:14695011, RGD:14695012, RGD:152177911 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pth1r parathyroid hormone 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14578863 PMID:17203219 RGD:2292584 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 susceptibility
disease_progression		 ISO DNA:SNP: :p.Y2081D(human) RGD PMID:26801674 PMID:16489062 RGD:152176666, RGD:152599190 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:30237408 RGD:151361293 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Pvt1 Pvt1 oncogene ISO mRNA:increased expression:liver (human) RGD PMID:30205391 RGD:153344577 NCBI chr 7:93,656,528...93,879,938 JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:17471463 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Pygl glycogen phosphorylase L ISO CTD Direct Evidence: marker/mechanism CTD PMID:2885971 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310 		JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)
protein:increased expression:liver (human)		 CTD
RGD		 PMID:18506888 PMID:33482578 PMID:20522449 RGD:153298967, RGD:153350129 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Rad21 RAD21 cohesin complex component treatment
exacerbates
susceptibility		 ISO human cells in a mouse model
mRNA:increased expression:liver (human)
associated with hepatitis c, liver cirrhosis;mRNA:increased expression:liver (human)		 RGD PMID:30698808 PMID:33251678 PMID:32596342 RGD:150520029, RGD:150520026, RGD:150520035 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:16385572 PMID:18281469 PMID:19409520 PMID:24894818 PMID:25452441 More... NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility
onset		 ISO associated with hepatitis B;DNA:SNP:3'utr: (rs7963551) (human)
mRNA,protein:increased expression:liver (human)		 RGD PMID:24729511 PMID:31719794 RGD:151361199, RGD:151361207 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rad54l RAD54 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Rara retinoic acid receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rb1 RB transcriptional corepressor 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12029619 PMID:14961299 PMID:33841550 RGD:152998960 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbm10 RNA binding motif protein 10 disease_progression ISO mRNA:decreased expression:liver RGD PMID:32572914 RGD:151356975 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rcan1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045 		JBrowse link
G Recql RecQ like helicase disease_progression ISO protein:increased expression:liver RGD PMID:18422747 PMID:18422747 RGD:2317370, RGD:2317370 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Reg3b regenerating family member 3 beta ISO mRNA:increased expression:liver (human) RGD PMID:10550309 RGD:9831380 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015 		JBrowse link
G Ret ret proto-oncogene severity ISO protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma		 RGD
ClinVar		 PMID:7784092 PMID:7845675 PMID:7911697 PMID:9111992 PMID:9242375 More... RGD:150340602 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rgn regucalcin IEP protein:decreased expression:liver RGD PMID:21683810 RGD:5509919 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 severity ISO mRNA, protein:increased expression:liver (human) RGD PMID:25371154 PMID:29303510 RGD:152995471, RGD:152995524 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rit1 Ras-like without CAAX 1 ameliorates ISO human cells in mouse model RGD PMID:31247273 RGD:152999016 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455 		JBrowse link
G Rnd3 Rho family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327 		JBrowse link
G Rnf157 ring finger protein 157 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942 		JBrowse link
G Rnf43 ring finger protein 43 exacerbates ISO human cells in a mouse model RGD PMID:23136185 RGD:151361219 NCBI chr10:72,461,508...72,537,301
Ensembl chr10:72,464,348...72,536,977 		JBrowse link
G Rnf6 ring finger protein 6 disease_progression ISO RGD PMID:30496760 RGD:151665757 NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847 		JBrowse link
G Robo1 roundabout guidance receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rps6 ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 PMID:28284560 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rspo3 R-spondin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:28,283,914...28,368,661
Ensembl chr 1:28,283,914...28,367,061 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNP: :rs9272105(human)
associated with Hepatitis B, Chronic;DNA:SNPs, haplotype: : rs9275572, rs2596542(human)		 RGD PMID:30160782 PMID:24204805 RGD:14398839, RGD:14401561 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Bb RT1 class II, locus Bb treatment ISO associated with hepatitis B
associated with hepatitis C;DNA:SNPs,haplotypes		 RGD PMID:27288300 PMID:28921602 RGD:14928325, RGD:14974233 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Ha RT1 class II, locus Ha ISO DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G Rtkn rhotekin ISO mRNA:increased expression:liver RGD PMID:27922690 RGD:19165144 NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952 		JBrowse link
G Rtp3 receptor (chemosensory) transporter protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17693185 NCBI chr 8:110,970,154...110,975,000
Ensembl chr 8:110,970,160...110,974,699 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO mRNA:decreased expression:liver RGD PMID:17094378 RGD:126775147 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver		 CTD
RGD		 PMID:28458013 PMID:17094378 RGD:126775147 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Rxra retinoid X receptor alpha ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Ryr3 ryanodine receptor 3 disease_progression ISO DNA:SNP:3'UTR:rs1044129(human) RGD PMID:26309413 RGD:155882454 NCBI chr 3:99,431,755...99,979,125
Ensembl chr 3:99,432,505...99,704,961 		JBrowse link
G S100a9 S100 calcium binding protein A9 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sardh sarcosine dehydrogenase severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Sav1 salvador family WW domain containing protein 1 ISS OMIM:114550 MouseDO NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968 		JBrowse link
G Scap SREBF chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666 		JBrowse link
G Scd stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6258829 PMID:21472284 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpina4 serpin family A member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:19709125 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpinb5 serpin family B member 5 disease_progression ISO associated with hepatitis B; RGD PMID:26296971 RGD:11520929 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756 		JBrowse link
G Serpinf1 serpin family F member 1 ISO associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Set Set nuclear proto-oncogene ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26822237 NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 disease_progression
treatment		 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma
protein:increased expression:liver
mRNA, protein:increased expression:liver		 ClinVar
RGD		 PMID:23634996 PMID:26619011 PMID:29954402 PMID:29954402 PMID:33038489 More... RGD:126790493, RGD:126790493, RGD:126790494, RGD:126790494 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 treatment
severity		 IEP
ISO		 mRNA, protein:increased expression:liver (rat)
mRNA, protein:increased expression:liver (human)
human cells in mouse model
mRNA, protein:increased expression:liver(human)		 RGD PMID:29059470 PMID:29059470 PMID:29059470 PMID:30391496 PMID:30391496 RGD:155791679, RGD:155791679, RGD:155791679, RGD:155804298, RGD:155804298 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33838155 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716 		JBrowse link
G Shc1 SHC adaptor protein 1 IEP protein:increased expression, increased phosphorylation:hepatocyte RGD PMID:15375560 RGD:1643188 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sik2 salt-inducible kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34491613 NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Six1 SIX homeobox 1 severity ISO protein:increased expression:liver (human) RGD PMID:17008870 RGD:11561961 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010 		JBrowse link
G Skp2 S-phase kinase associated protein 2 IEP
ISO		 protein:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12717389 PMID:19533683 RGD:2315050 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a22 solute carrier family 22 member 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 PMID:30705370 NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111 		JBrowse link
G Slc25a47 solute carrier family 25, member 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 ameliorates
disease_progression		 ISO RGD PMID:26389641 PMID:26389641 RGD:151361140, RGD:151361140 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 ISO CTD Direct Evidence: therapeutic CTD PMID:15347726 PMID:15520214 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 ameliorates
disease_progression		 ISO
IEP		 mRNA:increased expression:liver RGD PMID:26389641 PMID:26389641 PMID:23696029 PMID:7532544 RGD:151361140, RGD:151361140, RGD:151361280, RGD:634202 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 disease_progression
exacerbates		 ISO protein:decreased expression:liver (human)
mRNA,protein:decreased expression:liver (human)		 RGD PMID:21626360 PMID:32534581 RGD:152995417, RGD:152995423 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slit2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19100240 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smad2 SMAD family member 2 IDA RGD PMID:18971187 RGD:12880056 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad4 SMAD family member 4 disease_progression IEP
ISO		 protein:decreased expression:liver
protein:increased expression:liver:		 RGD PMID:18971187 PMID:23922662 PMID:22799322 PMID:29924446 RGD:12880056, RGD:18182921, RGD:21066341, RGD:21066342 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad7 SMAD family member 7 ISO mRNA:increased expression:liver (human) RGD PMID:25602745 RGD:14401589 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO DNA:SNPs: :rs11879293, rs2072382 (human) RGD PMID:24556940 RGD:127285650 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 disease_progression ISO mRNA:decreased expression:liver RGD PMID:27111394 RGD:127285647 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 ameliorates ISO mRNA, protein:increased expression:liver (human) RGD PMID:32514535 RGD:151347860 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 exacerbates ISO mRNA:increased editing:cds:p.K96R,p.Q103R(human) RGD PMID:29996118 RGD:156430111 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
G Smg9 SMG9 nonsense mediated mRNA decay factor severity ISO RGD PMID:34456727 RGD:155882446 NCBI chr 1:79,988,540...80,011,262
Ensembl chr 1:79,988,612...80,011,254 		JBrowse link
G Smo smoothened, frizzled class receptor disease_progression ISO DNA:SNP: :rs3824 (human) RGD PMID:25944162 RGD:150340548 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Snai1 snail family transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E ISO human gene in a mouse model RGD PMID:21688285 RGD:10768833 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snw1 SNW domain containing 1 severity ISO protein:increased expression:liver (human) RGD PMID:23696020 RGD:11035253 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Snx27 sorting nexin 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906 		JBrowse link
G Soat1 sterol O-acyltransferase 1 exacerbates ISO associated with hepatitis B;protein:increased expression:liver (human) RGD PMID:30814741 RGD:126925204 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Soat2 sterol O-acyltransferase 2 ISO RGD PMID:16274362 RGD:1581190 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment ISO
IEP		 associated with liver cirrhosis;DNA:altered methylation:liver:
DNA:hypermethylation:CpG island, 5'untranslated region:		 RGD PMID:14614012 PMID:18843197 PMID:15235874 PMID:22318090 RGD:150573687, RGD:150573689, RGD:150573700, RGD:150573703 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16831601 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 susceptibility
disease_progression		 ISO associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human)
protein:increased expression:saliva
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16767786 PMID:18760346 PMID:19731237 PMID:21472284 PMID:33010264 More... RGD:1581242, RGD:26923907, RGD:26923955, RGD:27095881 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression
exacerbates		 ISO RGD PMID:30312695 PMID:30312695 RGD:151660341, RGD:151660341 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Spag9 sperm associated antigen 9 ISO associated with Human Viral Hepatitis RGD PMID:29344208 RGD:30296654 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797 		JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959 		JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 ameliorates ISO human cells in mouse model RGD PMID:30710422 RGD:153344549 NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935 		JBrowse link
G Spop speckle type BTB/POZ protein exacerbates ISO mRNA:decreased expression:liver (human)
human cells in mouse model		 RGD PMID:26156804 PMID:33209975 RGD:11074965, RGD:153298924 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Spp1 secreted phosphoprotein 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:16047475 PMID:35693827 RGD:1581375, RGD:153344586 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sprtn SprT-like N-terminal domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25261934 NCBI chr19:52,857,612...52,864,864
Ensembl chr19:52,857,866...52,864,864 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO
IEP		 RGD PMID:9581679 PMID:9581679 RGD:150521543, RGD:150521543 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:21147110 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Srf serum response factor IDA RGD PMID:9570363 RGD:1581428 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 IEP mRNA:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 treatment
disease_progression		 ISO RGD PMID:32372053 PMID:28082404 PMID:29278882 RGD:150429663, RGD:150429666, RGD:150429692 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Ssx1 SSX family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:13,931,433...13,939,732
Ensembl chr  X:13,931,470...13,939,720 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO protein:increased activity:liver: RGD PMID:9331085 RGD:10043141 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310 		JBrowse link
G Stab2 stabilin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:21,249,426...21,433,051
Ensembl chr 7:21,249,391...21,434,042 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22488367 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 susceptibility ISO Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:23242368 PMID:26745093 RGD:11553302 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A ameliorates ISO RGD PMID:28100771 RGD:127285675 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B exacerbates
ameliorates		 ISO protein:increased expression:liver (human)
mRNA:increased expression:liver (human)		 RGD PMID:17047057 PMID:31485610 RGD:153298929, RGD:153298932 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stc2 stanniocalcin 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO mRNA:increased expression:liver (human) RGD PMID:23211538 RGD:152995401 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stmn1 stathmin 1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:28982915 RGD:21408578 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
G Tagln2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Taldo1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tatdn1 TatD DNase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:90,449,979...90,481,000
Ensembl chr 7:90,441,079...90,481,133 		JBrowse link
G Tbx3 T-box transcription factor 3 severity
disease_progression
ameliorates		 ISO protein:increased expression:liver (human)
human cells in mouse model		 RGD PMID:33577921 PMID:29295731 PMID:30578408 PMID:26922018 PMID:22811581 RGD:151361112, RGD:151361114, RGD:151361122, RGD:151361123, RGD:151361132 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tcf19 transcription factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271 		JBrowse link
G Tcim transcriptional and immune response regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581 		JBrowse link
G Tedc2 tubulin epsilon and delta complex 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:13,246,032...13,251,196
Ensembl chr10:13,246,037...13,251,124 		JBrowse link
G Tek TEK receptor tyrosine kinase IEP protein:increased expression RGD PMID:16951510 RGD:1601490 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tep1 telomerase associated protein 1 disease_progression
susceptibility		 ISO associated with hepatitis B;DNA:SNPs: :rs1713449,rs1760898, rs872072 (human)
DNA:SNP:intron:rs1760893(human)		 RGD PMID:23907815 PMID:27305982 RGD:152975963, RGD:152977750 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Tert telomerase reverse transcriptase disease_progression
treatment
no_association
susceptibility		 IEP
ISO		 protein:increased expression, increased localization:nucleus
CTD Direct Evidence: marker/mechanism
DNA:mutations:promoter:
DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human)
DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human
DNA:hypermethylation:promoter
DNA:SNPs::rs2736098(human)
ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with hepatitis B;DNA:SNP: :rs13167280 (human)		 CTD
ClinVar
RGD		 PMID:16651430 PMID:22634754 PMID:23000435 PMID:25362482 PMID:25741868 More... RGD:11038673, RGD:14696767, RGD:14696768, RGD:14696769, RGD:14696770, RGD:11564803, RGD:11530743, RGD:150530496, RGD:152975963 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 ISO protein:decreased expression:liver RGD PMID:23671639 RGD:9586747 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 severity
ameliorates
disease_progression		 ISO mRNA, protein:increased expression:liver (human)
human cells in mouse model
mRNA:decreased expression:liver (human)		 RGD PMID:26366235 PMID:29331390 PMID:29331390 PMID:33097695 PMID:30070373 RGD:150429684, RGD:150429595, RGD:150429595, RGD:150429597, RGD:150429689 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17464989 PMID:28284560 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tfrc transferrin receptor IEP mRNA:increased expression:liver RGD PMID:16953838 RGD:2292036 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfa transforming growth factor alpha IEP
ISO		 associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9029167 PMID:15565109 PMID:9060843 RGD:2317471 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (mouse)		 CTD
RGD		 PMID:9029167 PMID:28100771 RGD:127285675 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEP mRNA, protein:decreased expression:liver RGD PMID:14585397 RGD:1601598 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgm3 transglutaminase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075 		JBrowse link
G Th tyrosine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Them4 thioesterase superfamily member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr 2:181,953,550...181,974,708
Ensembl chr 2:181,953,550...181,974,708 		JBrowse link
G Thy1 Thy-1 cell surface antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523 		JBrowse link
G Timd4 T-cell immunoglobulin and mucin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:31,185,751...31,221,843
Ensembl chr10:31,185,731...31,220,966 		JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tlr2 toll-like receptor 2 susceptibility ISO associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human) RGD PMID:21500195 PMID:27183918 PMID:22859216 RGD:15090813, RGD:15090815, RGD:18337266 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 disease_progression ISO RGD PMID:23197495 RGD:21079421 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:
DNA:SNP: :rs1057317(human)
DNA:SNPs, haplotype: :multiples		 CTD
RGD		 PMID:27022031 PMID:28578348 PMID:25179842 PMID:21559380 RGD:14700552, RGD:14700557, RGD:14700558 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24990399 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr9 toll-like receptor 9 treatment ISO protein: increased expression:peripheral blood mononuclear cell (human)
human cells in a mouse model
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:24990399 PMID:18215354 PMID:24452201 RGD:18337472, RGD:18337468 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmem70 transmembrane protein 70 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 5:2,637,102...2,654,729
Ensembl chr 5:2,637,102...2,654,729 		JBrowse link
G Tnf tumor necrosis factor disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver, blood serum (mouse)		 CTD
RGD		 PMID:27022031 PMID:26890368 PMID:26569409 RGD:14975171, RGD:11344640 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 sexual_dimorphism
ameliorates		 ISO protein:decreased expression:liver (human)
mRNA,protein:increased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:27253414 PMID:32015333 PMID:26538215 PMID:29190981 RGD:151347600, RGD:151347604, RGD:151347618, RGD:151347622 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:17326159 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf9 TNF superfamily member 9 ISO RGD PMID:17325342 RGD:2317348 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase disease_progression ISO protein:increased phosphorylation:liver, nucleus (human) RGD PMID:25160513 RGD:151347837 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 treatment ISO
IEP		 protein:altered localization:cytoplasm, nucleus
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:missense mutation: :p.R249S (human)
mRNA:increased expression:liver (mouse)
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA		 CTD
ClinVar
OMIM
RGD		 PMID:253702 PMID:960674 PMID:1349102 PMID:1349175 PMID:1359493 More... RGD:1302543, RGD:14995503, RGD:14995934, RGD:127285675, RGD:152998960 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 exacerbates
treatment		 ISO protein:decreased phosphorylation:liver (human)
mRNA:increased expression:liver (human)
human cells in a mouse model		 RGD PMID:27359056 PMID:31429776 PMID:14760085 PMID:19664633 PMID:25371988 RGD:151347579, RGD:151347592, RGD:151347593, RGD:151347594, RGD:151347596 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Traf7 TNF receptor associated factor 7 treatment ISO mRNA:increased expression:liver RGD PMID:31730901 PMID:31730901 RGD:151356961, RGD:151356961 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
G Traip TRAF-interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638 		JBrowse link
G Trim24 tripartite motif-containing 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr 4:66,567,342...66,692,029
Ensembl chr 4:66,566,686...66,717,241 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
G Troap trophinin associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365 		JBrowse link
G Tsc1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21499249 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc2 TSC complex subunit 2 severity IEP protein:decreased expression:liver (human) RGD PMID:24119083 RGD:21079731 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tslp thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Tspy1 testis specific protein, Y-linked 1 ISO mRNA:increased expression:liver RGD PMID:16106251 RGD:2315447
G Tst thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:45,112,737...45,116,345 JBrowse link
G Ttk Ttk protein kinase disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Ttr transthyretin disease_progression ISO
IEP		 protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (human)
protein:increased expression:blood serum (rat)		 RGD PMID:29534342 PMID:16240287 PMID:28876464 PMID:28876464 RGD:151356736, RGD:151665161, RGD:151664602, RGD:151664602 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Txnip thioredoxin interacting protein ISS OMIM:114550 MouseDO NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Tyms thymidylate synthetase susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:deletion:3'UTR:1494del6(human)		 CTD
RGD		 PMID:18019677 PMID:18230555 PMID:17659576 RGD:14696708 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats ISS OMIM:114550 MouseDO NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
G Ubd ubiquitin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532 		JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 treatment ISO RGD PMID:32087767 RGD:151665344 NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18666234 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Umps uridine monophosphate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
G Uroc1 urocanate hydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 8:109,035,402...109,079,382
Ensembl chr 8:109,036,099...109,080,427 		JBrowse link
G Vasn vasorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25826090 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 IEP mRNA:decreased expression:liver RGD PMID:2064726 RGD:2306008 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vdr vitamin D receptor susceptibility ISO DNA:hypermethylation:promoter
associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human)
associated with alcoholic liver cirrhosis;DNA:haplotype::
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma		 ClinVar
RGD		 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29432829 PMID:25541958 More... RGD:14401747, RGD:14402025, RGD:14402026 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment
disease_progression
susceptibility		 ISO
IEP		 protein:increased expression:liver
DNA:polymorphism:promoter:-2578C>A (rs699947)(human)
protein:increased expression:serum:
associated with liver cirrhosis; protein:increased expression:platelet, liver:
DNA:SNP: :2578C>A (human)		 RGD PMID:27338800 PMID:28147320 PMID:28147320 PMID:18544126 PMID:26930285 More... RGD:15003194, RGD:15003196, RGD:15003196, RGD:15003200, RGD:11527070, RGD:15014783, RGD:15036790, RGD:126848814, RGD:152177911 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C ISO associated with liver cirrhosis; protein:increased expression:liver: RGD PMID:18544126 RGD:15003200 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor disease_progression ISO RGD PMID:31321740 RGD:155882550 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212 		JBrowse link
G Wdr62 WD repeat domain 62 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637 		JBrowse link
G Wdr76 WD repeat domain 76 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
G Wnt2 Wnt family member 2 susceptibility ISO associated with hepatitis B;DNA:SNP: :rs4730775(human) RGD PMID:28328801 RGD:14402040 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISO RNA:increased expression:liver: RGD PMID:26551349 RGD:11096781 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xdh xanthine dehydrogenase IEP protein:decreased activity:tumor (rat) RGD PMID:179860 RGD:5135059 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xpo1 exportin 1 ameliorates
treatment
exacerbates		 ISO
IDA		 human cell line in a mouse model
mRNA:increased expression:liver (human)		 RGD PMID:25030088 PMID:27013579 PMID:31371628 RGD:151665796, RGD:151667433, RGD:151667441 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xpo5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24676133 RGD:11041737 NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
severity
no_association
disease_progression		 ISO DNA:missense mutation:cds:p.R399Q (rs25487) (human)
DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human)
DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human)
DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human)
DNA:missense mutation:cds:c.1804C>A (p.G506A) (human)
DNA:missense mutation:cds:p.R399Q (human)
DNA:SNPs:exons:c.1254C>T, c.1517G>C (human)
associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human)
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human)
DNA:SNPs:cds: 194C>T, 280A>G (human)
DNA:SNP:exon 13: c.1471G>A, p.E491K (human)
DNA:SNPs:exon 9, exon 15: c.910A>G, c.1686C>G (human)
associated with Chronic Hepatitis C;DNA:SNP:exon 14: c.1517G>C, p.506G>A (human)		 GAD
RGD		 PMID:15118671 PMID:28058700 PMID:24570146 PMID:23493666 PMID:29682247 More... RGD:1331525, RGD:14696702, RGD:14696772, RGD:14696773, RGD:14985238, RGD:14985240, RGD:14985242, RGD:14985243, RGD:15014789, RGD:15014790, RGD:15014791, RGD:15014792, RGD:15036794, RGD:15036797, RGD:15036797, RGD:150530503, RGD:150530624, RGD:150540332, RGD:150540333 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29698666 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28104805 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta severity ISO RGD PMID:27811373 RGD:14700875 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D ISO CTD Direct Evidence: marker/mechanism CTD PMID:34545456 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
G Zfhx3 zinc finger homeobox 3 severity
disease_progression		 ISO human cell line in a mouse model
associated with Chronic Hepatitis B;protein:decreased expression:blood serum (human)		 RGD PMID:32277050 PMID:20534899 RGD:151361162, RGD:151361169 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
G Zfp36 zinc finger protein 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
G Zfp612 zinc finger protein 612 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21965783 NCBI chr19:38,053,953...38,071,196
Ensembl chr19:38,053,967...38,067,455 		JBrowse link
G Zic2 Zic family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
G Zic4 Zic family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:91,916,356...91,936,525
Ensembl chr 8:91,920,015...91,935,368 		JBrowse link
G Zic5 Zic family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:99,558,285...99,567,023
Ensembl chr15:99,560,323...99,567,035 		JBrowse link
G Zwint ZW10 interacting kinetochore protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
aflatoxins-related hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 IEP associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
childhood hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Pediatric hepatocellular carcinoma ClinVar PMID:9927037 PMID:17483355 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
fibrolamellar carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car12 carbonic anhydrase 12 ISO mRNA:increased expression:liver RGD PMID:28304380 RGD:153352326 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Ctnnb1 catenin beta 1 ISO protein:increased tyrosine phosphorylation:exon: RGD PMID:19101982 RGD:14402052 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO protein:increased expression:liver: RGD PMID:24925055 RGD:11055933 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO mRNA,protein:increased expression:liver (human) RGD PMID:27027723 RGD:151347845 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
hepatocellular clear cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO DNA:misssense mutation:cds:p.Arg132Cys(human)
DNA:polymorphism: :rs12478635(human)		 RGD PMID:28403884 PMID:25355558 RGD:14974227, RGD:14974228 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO DNA:polymorphism: :rs11632348(human) RGD PMID:25355558 RGD:14974228 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lep leptin ISO mRNA:increased expression:liver: RGD PMID:20723213 RGD:14696785 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor ISO mRNA:increased expression:liver: RGD PMID:20723213 RGD:14696785 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO mRNA:increased expression:liver: RGD PMID:28460432 PMID:20723213 RGD:14696783, RGD:14696785 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
mixed fibrolamellar hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkaca protein kinase cAMP-activated catalytic subunit alpha susceptibility ISO RGD PMID:28923495 RGD:151347843 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
Ruijs-Aalfs syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sprtn SprT-like N-terminal domain ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome | ClinVar Annotator: match by term: Ruijs-Aalfs syndrome		 OMIM
CTD
ClinVar		 PMID:12503110 PMID:25261934 PMID:25741868 NCBI chr19:52,857,612...52,864,864
Ensembl chr19:52,857,866...52,864,864 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    disease of cellular proliferation 7667
      cancer 5483
        cell type cancer 3731
          carcinoma 3200
            adenocarcinoma 1713
              hepatocellular carcinoma 949
                Hepatoblastoma Caused By Somatic Mutation 0
                Ruijs-Aalfs syndrome 1
                adult hepatocellular carcinoma 0
                aflatoxins-related hepatocellular carcinoma 2
                childhood hepatocellular carcinoma 1
                fibrolamellar carcinoma + 4
                hepatocellular clear cell carcinoma 5
                sclerosing hepatic carcinoma 0
Path 2
Term Annotations click to browse term
  disease 21128
    disease of cellular proliferation 7667
      Neoplasms by Site 7121
        Digestive System Neoplasms 3836
          Gastrointestinal Neoplasms 3711
            gastrointestinal system cancer 2909
              hepatobiliary system cancer 1103
                liver cancer 1014
                  liver carcinoma 954
                    hepatocellular carcinoma 949
                      Hepatoblastoma Caused By Somatic Mutation 0
                      Ruijs-Aalfs syndrome 1
                      adult hepatocellular carcinoma 0
                      aflatoxins-related hepatocellular carcinoma 2
                      childhood hepatocellular carcinoma 1
                      fibrolamellar carcinoma + 4
                      hepatocellular clear cell carcinoma 5
                      sclerosing hepatic carcinoma 0
paths to the root