| 1,10-phenanthroline | increases expression | ISO | RGD:1313299 | 6480464 | 1,10-phenanthroline results in increased expression of MDM2 mRNA | CTD | PMID:19502547 |
| 17alpha-ethynylestradiol | increases expression | ISO | RGD:1313299 | 6480464 | Ethinyl Estradiol results in increased expression of MDM2 mRNA alternative form; more ... | CTD | PMID:12168835 |
| 17alpha-ethynylestradiol | increases expression | ISO | RGD:1313300 | 6480464 | Ethinyl Estradiol results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1313300 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | affects expression | ISO | RGD:1313300 | 6480464 | Ethinyl Estradiol affects the expression of MDM2 mRNA | CTD | PMID:17555576 |
| 17beta-estradiol | increases expression | ISO | RGD:1313299 | 6480464 | Estradiol results in increased expression of MDM2 mRNA alternative form; more ... | CTD | PMID:12168835 |
| 17beta-estradiol | decreases phosphorylation | ISO | RGD:1313300 | 6480464 | Estradiol results in decreased phosphorylation of MDM2 protein | CTD | PMID:22314386 |
| 2,2',3,3',6,6'-hexachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 2,3,6,2',3',6'-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 PMID:20840854 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1313299 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein] | CTD | PMID:20840854 |
| 2,2',4,4'-tetrachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 2,4,2',4'-tetrachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 2,2',5,5'-tetrachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 2,5,2',5'-tetrachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1313299 | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; more ... | CTD | PMID:19578757 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1313300 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MDM2 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1313300 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:12167310 PMID:21041162 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1313299 | 6480464 | Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein]; more ... | CTD | PMID:22044530 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1313300 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:21041162 PMID:12167310 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein | CTD | PMID:15459018 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]; more ... | CTD | PMID:15459018 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases degradation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased degradation of MDM2 protein | CTD | PMID:15459018 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1313300 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:12167310 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1313300 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1313299 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:19578757 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1313299 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MDM2 mRNA | CTD | PMID:16039398 |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of MDM2 mRNA | CTD | PMID:21346803 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of MDM2 mRNA | CTD | PMID:21346803 |
| 2-acetamidofluorene | increases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in increased expression of MDM2 mRNA; more ... | CTD | PMID:19167416 |
| 2-acetamidofluorene | increases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in increased expression of MDM2 mRNA | CTD | PMID:19167416 PMID:22584684 |
| 2-acetamidofluorene | increases expression | ISO | RGD:1313300 | 6480464 | 2-Acetylaminofluorene results in increased expression of MDM2 mRNA | CTD | PMID:21607683 |
| 2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein | CTD | PMID:11003613 |
| 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:14600272 |
| 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of MDM2 mRNA | CTD | PMID:14600272 PMID:15890375 |
| 3,3',4,4',5-pentachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | RGD:1313299 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; more ... | CTD | PMID:20840854 |
| 3,3',4,4',5-pentachlorobiphenyl | increases phosphorylation | ISO | RGD:1313299 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 PMID:20840854 |
| 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:1313300 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of MDM2 mRNA | CTD | PMID:18648102 |
| 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA | CTD | PMID:14600272 PMID:15890375 |
| 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:14600272 |
| 4-hydroperoxycyclophosphamide | increases expression | ISO | RGD:1313299 | 6480464 | perfosfamide results in increased expression of MDM2 | CTD | PMID:18034189 |
| 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1313299 | 6480464 | Fenretinide results in decreased expression of MDM2 mRNA | CTD | PMID:16570282 |
| 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:1313299 | 6480464 | decitabine affects the expression of MDM2 mRNA | CTD | PMID:17145863 |
| 5-fluorouracil | increases expression | ISO | RGD:1313300 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:16949053 |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:14665630 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:14665630 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:15546879 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:19098008 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:17982676 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:16557594 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| 5-fluorouracil | multiple interactions | ISO | RGD:1313299 | 6480464 | TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 mRNA] | CTD | PMID:17982676 |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 protein | CTD | PMID:19098008 more ... |
| 5-fluorouracil | increases expression | ISO | RGD:1313299 | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:14665630 more ... |
| 5-fluorouracil | multiple interactions | ISO | RGD:1313299 | 6480464 | Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]; more ... | CTD | PMID:15546879 |
| acetylsalicylic acid | decreases expression | ISO | RGD:1313299 | 6480464 | Aspirin results in decreased expression of MDM2 mRNA | CTD | PMID:20457246 |
| aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:14600272 PMID:15890375 |
| aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
| aflatoxin B1 | increases expression | ISO | RGD:1313299 | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:21632981 PMID:21641981 |
| aflatoxin B1 | increases expression | ISO | RGD:1313299 | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:21641981 |
| aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:14600272 |
| aflatoxin B1 | increases expression | ISO | RGD:1313300 | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:19770486 |
| aflatoxin B1 | affects expression | ISO | RGD:1313299 | 6480464 | Aflatoxin B1 affects the expression of MDM2 protein | CTD | PMID:20106945 |
| amifostine | decreases expression | ISO | RGD:1313299 | 6480464 | Amifostine results in decreased expression of MDM2 mRNA | CTD | PMID:14555708 |
| ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of MDM2 protein | CTD | PMID:16483693 |
| ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:12420312 |
| amsacrine | decreases response to substance | ISO | RGD:1313299 | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Amsacrine | CTD | PMID:17575151 |
| arsenic atom | affects response to substance | ISO | RGD:1313299 | 6480464 | MDM2 SNP affects the susceptibility to Arsenic | CTD | PMID:21982800 |
| arsenite(3-) | multiple interactions | ISO | RGD:1313299 | 6480464 | [[[arsenite results in increased activity of PRKDC protein] which results in increased phosphorylation of and results in increased activity of MAPK9 protein] promotes the reaction [MAPK9 protein binds to TP53 protein]] inhibits the reaction [MDM2 results in increased degradation of and results in decreased stability of TP53 protein] | CTD | PMID:22366412 |
| benzene | multiple interactions | ISO | RGD:1313300 | 6480464 | TRP53 protein affects the reaction [Benzene results in increased expression of MDM2 mRNA] | CTD | PMID:11896287 |
| benzene | increases expression | ISO | RGD:1313300 | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:11896287 more ... |
| benzene | multiple interactions | ISO | RGD:1313299 | 6480464 | MDM2 gene polymorphism affects the reaction [CDKN2A gene polymorphism affects the susceptibility to Benzene] | CTD | PMID:19596022 |
| benzene | increases expression | ISO | RGD:1313300 | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:15342939 more ... |
| benzene | increases expression | ISO | RGD:1313300 | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:11896287 more ... |
| benzene | increases expression | ISO | RGD:1313300 | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:15935812 more ... |
| benzene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
| benzene | increases expression | ISO | RGD:1313300 | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:15342939 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1313299 | 6480464 | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of MDM2 mRNA | CTD | PMID:17690111 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:10837373 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of MDM2 protein | CTD | PMID:21467743 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of and results in increased phosphorylation of MDM2 protein | CTD | PMID:18096571 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:10837373 more ... |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1313299 | 6480464 | 2,4,4'-trichlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; more ... | CTD | PMID:20840854 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| benzo[a]pyrene | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased phosphorylation of MDM2 protein | CTD | PMID:20840854 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:10837373 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:20106945 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:19146932 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 protein modified form | CTD | PMID:22044530 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18418871 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:10837373 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1313299 | 6480464 | TP53 affects the reaction [Benzo(a)pyrene results in increased expression of MDM2 mRNA] | CTD | PMID:10837373 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:19146932 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18418871 PMID:20106945 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 PMID:19146932 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:20106945 PMID:18418871 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1313299 | 6480464 | Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]; more ... | CTD | PMID:15625077 |
| benzo[a]pyrene | increases expression | ISO | RGD:1313300 | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1313300 | 6480464 | Mustard Gas results in increased expression of MDM2 mRNA | CTD | PMID:18955075 PMID:15674843 |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1313300 | 6480464 | Mustard Gas results in increased expression of MDM2 mRNA | CTD | PMID:15674843 PMID:18955075 |
| bis(2-chloroethyl) sulfide | affects expression | EXP | | 6480464 | Mustard Gas affects the expression of MDM2 mRNA | CTD | PMID:15651846 |
| brassinolide | decreases expression | ISO | RGD:1313299 | 6480464 | brassinolide results in decreased expression of MDM2 protein | CTD | PMID:20833159 |
| cadmium atom | decreases expression | EXP | | 6480464 | Cadmium results in decreased expression of MDM2 mRNA | CTD | PMID:21467746 |
| cadmium atom | increases expression | ISO | RGD:1313300 | 6480464 | Cadmium results in increased expression of MDM2 mRNA | CTD | PMID:22666406 |
| cadmium dichloride | increases phosphorylation | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased phosphorylation of MDM2 protein | CTD | PMID:20525538 |
| cadmium dichloride | increases expression | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:11958953 more ... |
| cadmium dichloride | multiple interactions | ISO | RGD:1313300 | 6480464 | MT1 affects the reaction [Cadmium Chloride results in increased expression of MDM2 mRNA]; more ... | CTD | PMID:11958953 |
| cadmium dichloride | increases phosphorylation | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased phosphorylation of MDM2 protein | CTD | PMID:20525538 PMID:22314386 |
| cadmium dichloride | increases expression | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:20061341 more ... |
| cadmium dichloride | multiple interactions | ISO | RGD:1313300 | 6480464 | Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] | CTD | PMID:12135628 |
| cadmium dichloride | increases phosphorylation | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased phosphorylation of MDM2 protein | CTD | PMID:22314386 PMID:20525538 |
| cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of MDM2 mRNA | CTD | PMID:22110744 |
| cadmium dichloride | increases expression | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:20061341 PMID:22314386 |
| cadmium dichloride | increases expression | ISO | RGD:1313300 | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:20061341 |
| camptothecin | increases expression | ISO | RGD:1313299 | 6480464 | Camptothecin results in increased expression of MDM2 protein | CTD | PMID:17555331 |
| capsaicin | multiple interactions | ISO | RGD:1313299 | 6480464 | Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; more ... | CTD | PMID:19846903 |
| capsaicin | increases expression | ISO | RGD:1313299 | 6480464 | Capsaicin results in increased expression of MDM2 mRNA | CTD | PMID:19502594 |
| capsaicin | decreases expression | ISO | RGD:1313299 | 6480464 | Capsaicin results in decreased expression of MDM2 protein | CTD | PMID:19846903 |
| chlorambucil | increases expression | ISO | RGD:1313299 | 6480464 | Chlorambucil results in increased expression of MDM2 mRNA | CTD | PMID:17476690 |
| choline | multiple interactions | ISO | RGD:1313300 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDM2 gene | CTD | PMID:20938992 |
| cisplatin | multiple interactions | ISO | RGD:1313299 | 6480464 | Cisplatin promotes the reaction [TP53 protein binds to MDM2 promoter]; more ... | CTD | PMID:21552291 |
| cisplatin | multiple interactions | ISO | RGD:1313300 | 6480464 | Cisplatin promotes the reaction [TRP53 protein results in increased expression of MDM2] | CTD | PMID:21552291 |
| cisplatin | increases expression | ISO | RGD:1313300 | 6480464 | Cisplatin results in increased expression of MDM2 mRNA | CTD | PMID:21151649 |
| cisplatin | multiple interactions | ISO | RGD:1313299 | 6480464 | [TP53 protein binds to MDM2 protein] which results in decreased susceptibility to Cisplatin | CTD | PMID:21509038 |
| cisplatin | increases expression | ISO | RGD:1313299 | 6480464 | Cisplatin results in increased expression of MDM2 protein | CTD | PMID:16797627 |
| cisplatin | multiple interactions | ISO | RGD:1313299 | 6480464 | Cisplatin results in increased activity of and results in increased expression of MDM2 protein; more ... | CTD | PMID:21624110 |
| clofibrate | multiple interactions | ISO | RGD:1313300 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA; more ... | CTD | PMID:17585979 |
| cobalt dichloride | increases expression | ISO | RGD:1313299 | 6480464 | cobaltous chloride results in increased expression of MDM2 protein | CTD | PMID:19714248 |
| cobalt dichloride | multiple interactions | ISO | RGD:1313299 | 6480464 | MDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]] | CTD | PMID:19714248 |
| copper atom | increases expression | ISO | RGD:1313299 | 6480464 | Copper results in increased expression of MDM2 mRNA | CTD | PMID:16629173 |
| copper(0) | increases expression | ISO | RGD:1313299 | 6480464 | Copper results in increased expression of MDM2 mRNA | CTD | PMID:16629173 |
| curcumin | decreases expression | ISO | RGD:1313299 | 6480464 | Curcumin results in decreased expression of MDM2 mRNA; more ... | CTD | PMID:17332326 |
| cyclosporin A | increases expression | ISO | RGD:1313299 | 6480464 | Cyclosporine results in increased expression of MDM2 mRNA | CTD | PMID:20106945 |
| diarsenic trioxide | decreases expression | ISO | RGD:1313299 | 6480464 | arsenic trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:20458559 |
| diarsenic trioxide | decreases expression | EXP | | 6480464 | arsenic trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:21145380 |
| diarsenic trioxide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [arsenic trioxide results in increased expression of MDM2 mRNA] | CTD | PMID:17487067 |
| diarsenic trioxide | increases expression | EXP | | 6480464 | arsenic trioxide results in increased expression of MDM2 mRNA | CTD | PMID:17487067 |
| diarsenic trioxide | increases expression | ISO | RGD:1313299 | 6480464 | arsenic trioxide results in increased expression of MDM2 mRNA | CTD | PMID:20862710 |
| diclofenac | decreases expression | EXP | | 6480464 | Diclofenac results in decreased expression of MDM2 mRNA | CTD | PMID:17202759 |
| diepoxybutane | multiple interactions | ISO | RGD:1313299 | 6480464 | erythritol anhydride inhibits the reaction [TP53 protein binds to MDM2 protein] | CTD | PMID:20024960 |
| diethylstilbestrol | affects mutagenesis | ISO | RGD:1313300 | 6480464 | Diethylstilbestrol affects the mutagenesis of MDM2 gene | CTD | PMID:7916985 |
| diethylstilbestrol | decreases expression | ISO | RGD:1313300 | 6480464 | Diethylstilbestrol results in decreased expression of MDM2 mRNA | CTD | PMID:21041162 |
| diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of MDM2 mRNA | CTD | PMID:15890375 |
| diethylstilbestrol | increases expression | ISO | RGD:1313300 | 6480464 | Diethylstilbestrol results in increased expression of MDM2 mRNA | CTD | PMID:15545218 |
| dimethylarsinic acid | increases expression | EXP | | 6480464 | Cacodylic Acid results in increased expression of MDM2 mRNA | CTD | PMID:17481689 |
| dioxygen | multiple interactions | ISO | RGD:1313299 | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; more ... | CTD | PMID:19578757 |
| dioxygen | increases expression | ISO | RGD:1313299 | 6480464 | Oxygen deficiency results in increased expression of MDM2 protein | CTD | PMID:19578757 PMID:19714248 |
| dioxygen | increases expression | ISO | RGD:1313299 | 6480464 | Oxygen deficiency results in increased expression of MDM2 mRNA | CTD | PMID:19578757 PMID:19502547 |
| dioxygen | increases expression | ISO | RGD:1313299 | 6480464 | Oxygen deficiency results in increased expression of MDM2 mRNA | CTD | PMID:19502547 PMID:19578757 |
| dioxygen | increases expression | ISO | RGD:1313299 | 6480464 | Oxygen deficiency results in increased expression of MDM2 mRNA; more ... | CTD | PMID:19578757 |
| docetaxel anhydrous | increases expression | ISO | RGD:1313299 | 6480464 | docetaxel results in increased expression of MDM2 protein | CTD | PMID:16080190 PMID:16797627 |
| docetaxel anhydrous | increases expression | ISO | RGD:1313299 | 6480464 | docetaxel results in increased expression of MDM2 protein | CTD | PMID:16797627 PMID:16080190 |
| doxorubicin | multiple interactions | ISO | RGD:1313299 | 6480464 | Doxorubicin inhibits the reaction [TP53 protein binds to MDM2 protein] | CTD | PMID:19351845 |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| doxorubicin | multiple interactions | ISO | RGD:1313299 | 6480464 | MDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]]; more ... | CTD | PMID:19714248 |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:17959036 more ... |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:19560264 more ... |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:19074854 more ... |
| doxorubicin | increases expression | ISO | RGD:1313300 | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA | CTD | PMID:14766674 PMID:16949053 |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:19560264 more ... |
| doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA | CTD | PMID:12187937 |
| doxorubicin | multiple interactions | ISO | RGD:1313300 | 6480464 | pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA] | CTD | PMID:14766674 |
| doxorubicin | increases expression | ISO | RGD:1313300 | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA | CTD | PMID:16949053 PMID:14766674 |
| doxorubicin | multiple interactions | ISO | RGD:1313299 | 6480464 | wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein] | CTD | PMID:17935137 |
| doxorubicin | multiple interactions | ISO | RGD:1313299 | 6480464 | IFNA1 protein promotes the reaction [Doxorubicin results in increased expression of MDM2 protein] | CTD | PMID:17959036 |
| doxorubicin | increases expression | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
| doxorubicin | multiple interactions | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased activity of and results in increased expression of MDM2 protein; more ... | CTD | PMID:21624110 |
| doxorubicin | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Doxorubicin results in increased phosphorylation of MDM2 protein | CTD | PMID:17935137 |
| ethanol | decreases expression | ISO | RGD:1313300 | 6480464 | Ethanol results in decreased expression of MDM2 mRNA | CTD | PMID:22535522 |
| etoposide | multiple interactions | ISO | RGD:1313299 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] | CTD | PMID:17575151 |
| etoposide | increases expression | ISO | RGD:1313299 | 6480464 | Etoposide results in increased expression of MDM2 mRNA | CTD | PMID:16120219 |
| etoposide | increases expression | ISO | RGD:1313299 | 6480464 | Etoposide results in increased expression of MDM2 protein | CTD | PMID:16120219 PMID:18096571 |
| etoposide | increases expression | ISO | RGD:1313299 | 6480464 | Etoposide results in increased expression of MDM2 protein | CTD | PMID:18096571 |
| etoposide | increases expression | EXP | | 6480464 | Etoposide results in increased expression of MDM2 protein | CTD | PMID:15459018 |
| etoposide | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein] | CTD | PMID:15459018 |
| etoposide | multiple interactions | ISO | RGD:1313299 | 6480464 | wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein] | CTD | PMID:17935137 |
| etoposide | decreases response to substance | ISO | RGD:1313299 | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Etoposide | CTD | PMID:17575151 |
| etoposide | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Etoposide results in increased phosphorylation of MDM2 protein | CTD | PMID:17935137 |
| flucytosine | increases expression | ISO | RGD:1313299 | 6480464 | Flucytosine results in increased expression of MDM2 protein | CTD | PMID:15592511 |
| fluoranthene | multiple interactions | ISO | RGD:1313299 | 6480464 | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of MDM2 mRNA | CTD | PMID:17690111 |
| folic acid | affects expression | ISO | RGD:1313299 | 6480464 | Folic Acid affects the expression of MDM2 mRNA | CTD | PMID:16361273 |
| folic acid | multiple interactions | ISO | RGD:1313300 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDM2 gene | CTD | PMID:20938992 |
| formaldehyde | increases expression | ISO | RGD:1313299 | 6480464 | Formaldehyde results in increased expression of MDM2 mRNA; more ... | CTD | PMID:18045764 |
| formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of MDM2 mRNA; more ... | CTD | PMID:18045764 |
| fumonisin B1 | multiple interactions | ISO | RGD:1313299 | 6480464 | fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; more ... | CTD | PMID:18206046 |
| furan | increases expression | EXP | | 6480464 | furan results in increased expression of MDM2 mRNA | CTD | PMID:22079235 |
| furosemide | affects expression | EXP | | 6480464 | Furosemide affects the expression of MDM2 mRNA | CTD | PMID:17497460 |
| ganciclovir | increases expression | ISO | RGD:1313299 | 6480464 | Ganciclovir results in increased expression of MDM2 protein | CTD | PMID:15592511 |
| genistein | decreases expression | ISO | RGD:1313300 | 6480464 | Genistein results in decreased expression of MDM2 mRNA | CTD | PMID:21048042 |
| hydrogen peroxide | multiple interactions | ISO | RGD:1313299 | 6480464 | Hydrogen Peroxide promotes the reaction [TP53 protein binds to MDM2 promoter]; more ... | CTD | PMID:21552291 |
| hydrogen peroxide | increases expression | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of MDM2 mRNA | CTD | PMID:14689451 |
| hydrogen peroxide | multiple interactions | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of and affects the localization of MDM2 protein | CTD | PMID:14689451 |
| hydrogen peroxide | multiple interactions | ISO | RGD:1313300 | 6480464 | Hydrogen Peroxide promotes the reaction [TRP53 protein results in increased expression of MDM2] | CTD | PMID:21552291 |
| hydroxyurea | increases expression | ISO | RGD:1313299 | 6480464 | Hydroxyurea results in increased expression of MDM2 mRNA | CTD | PMID:18647660 |
| hydroxyurea | increases expression | ISO | RGD:1313300 | 6480464 | Hydroxyurea results in increased expression of MDM2 mRNA | CTD | PMID:16356682 |
| hydroxyurea | affects expression | ISO | RGD:1313300 | 6480464 | Hydroxyurea affects the expression of MDM2 protein | CTD | PMID:16356682 |
| isoflurane | decreases expression | EXP | | 6480464 | Isoflurane results in decreased expression of MDM2 mRNA | CTD | PMID:16978161 |
| kojic acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA | CTD | PMID:18544905 |
| L-ascorbic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] | CTD | PMID:21262251 |
| L-methionine | multiple interactions | ISO | RGD:1313300 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDM2 gene | CTD | PMID:20938992 |
| leptomycin B | increases expression | ISO | RGD:1313299 | 6480464 | leptomycin B results in increased expression of MDM2 mRNA | CTD | PMID:20803015 |
| linalool | increases expression | ISO | RGD:1313299 | 6480464 | linalool results in increased expression of MDM2 mRNA | CTD | PMID:19922762 |
| methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:18619722 |
| methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of MDM2 mRNA | CTD | PMID:22584684 |
| methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of MDM2 mRNA | CTD | PMID:18619722 PMID:15890375 |
| methotrexate | multiple interactions | ISO | RGD:1313299 | 6480464 | Methotrexate results in increased activity of and results in increased expression of MDM2 protein; more ... | CTD | PMID:21624110 |
| methotrexate | affects expression | ISO | RGD:1313300 | 6480464 | Methotrexate affects the expression of MDM2 mRNA | CTD | PMID:18502557 |
| methotrexate | increases expression | ISO | RGD:1313299 | 6480464 | Methotrexate results in increased expression of MDM2 protein | CTD | PMID:17637740 |
| methylarsonic acid | increases expression | EXP | | 6480464 | monomethylarsonic acid results in increased expression of MDM2 mRNA | CTD | PMID:17481689 |
| methylmercury(1+) | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
| mifepristone | increases expression | ISO | RGD:1313300 | 6480464 | Mifepristone results in increased expression of MDM2 mRNA | CTD | PMID:12605714 |
| mitomycin C | multiple interactions | ISO | RGD:1313299 | 6480464 | [Mitomycin results in increased stability of TP53 protein] which results in increased expression of MDM2 mRNA | CTD | PMID:20536192 |
| mitomycin C | increases expression | ISO | RGD:1313299 | 6480464 | Mitomycin results in increased expression of MDM2 protein | CTD | PMID:18096571 |
| mitoxantrone | decreases response to substance | ISO | RGD:1313299 | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Mitoxantrone | CTD | PMID:17575151 |
| monocrotaline | multiple interactions | ISO | RGD:1313300 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
| N-ethyl-N-nitrosourea | increases expression | EXP | | 6480464 | Ethylnitrosourea results in increased expression of MDM2 mRNA | CTD | PMID:15954086 |
| N-ethyl-N-nitrosourea | increases expression | ISO | RGD:1313300 | 6480464 | Ethylnitrosourea results in increased expression of MDM2 mRNA | CTD | PMID:19100860 |
| N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | RGD:1313299 | 6480464 | Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA | CTD | PMID:12634122 |
| N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | RGD:1313300 | 6480464 | Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] | CTD | PMID:12135628 |
| N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | RGD:1313300 | 6480464 | Methylnitronitrosoguanidine results in increased expression of MDM2 protein | CTD | PMID:12135628 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1313300 | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:19100860 PMID:17854601 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1313300 | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:17854601 more ... |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:14555611 PMID:15459018 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1313300 | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:17854601 PMID:19100860 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of MDM2 protein | CTD | PMID:14555611 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:15459018 PMID:14555611 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1313300 | 6480464 | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MDM2 mRNA] | CTD | PMID:17854601 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1313300 | 6480464 | Diethylnitrosamine results in increased expression of MDM2 protein | CTD | PMID:18506893 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein | CTD | PMID:11003613 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA | CTD | PMID:18544905 |
| N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:14600272 PMID:15890375 |
| N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:14600272 |
| nicotinamide | increases expression | ISO | RGD:1313299 | 6480464 | Niacinamide results in increased expression of MDM2 mRNA | CTD | PMID:16998810 |
| paclitaxel | decreases response to substance | ISO | RGD:1313299 | 6480464 | MDM2 protein results in decreased susceptibility to Paclitaxel | CTD | PMID:13130078 |
| paracetamol | multiple interactions | ISO | RGD:1313300 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA; more ... | CTD | PMID:17585979 |
| paracetamol | increases expression | ISO | RGD:1313299 | 6480464 | Acetaminophen results in increased expression of MDM2 mRNA | CTD | PMID:22230336 |
| paracetamol | decreases expression | ISO | RGD:1313299 | 6480464 | Acetaminophen results in decreased expression of MDM2 mRNA | CTD | PMID:21420995 |
| paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MDM2 mRNA | CTD | PMID:21807079 |
| paracetamol | increases phosphorylation | EXP | | 6480464 | Acetaminophen results in increased phosphorylation of MDM2 protein | CTD | PMID:16330492 |
| paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MDM2 mRNA | CTD | PMID:17202762 |
| paracetamol | multiple interactions | EXP | | 6480464 | Acetaminophen promotes the reaction [MDM2 protein binds to TP53 protein] | CTD | PMID:16330492 |
| paracetamol | affects expression | ISO | RGD:1313300 | 6480464 | Acetaminophen affects the expression of MDM2 mRNA | CTD | PMID:17562736 |
| paraquat | multiple interactions | ISO | RGD:1313300 | 6480464 | GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA] | CTD | PMID:12654481 |
| paraquat | increases expression | ISO | RGD:1313299 | 6480464 | Paraquat results in increased expression of MDM2 mRNA | CTD | PMID:20883675 |
| parathion-methyl | increases expression | ISO | RGD:1313299 | 6480464 | Methyl Parathion results in increased expression of MDM2 mRNA | CTD | PMID:18418871 |
| PD123319 | multiple interactions | ISO | RGD:1313299 | 6480464 | PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; more ... | CTD | PMID:18206046 |
| perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of MDM2 mRNA | CTD | PMID:19162173 |
| phenobarbital | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Phenobarbital results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
| phenobarbital | increases expression | ISO | RGD:1313300 | 6480464 | Phenobarbital results in increased expression of MDM2 mRNA | CTD | PMID:19482888 PMID:20816995 |
| phenobarbital | multiple interactions | ISO | RGD:1313300 | 6480464 | NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of MDM2 mRNA]; more ... | CTD | PMID:19482888 |
| phenytoin | multiple interactions | ISO | RGD:1313300 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
| phlorizin | decreases expression | ISO | RGD:1313300 | 6480464 | Phlorhizin results in decreased expression of MDM2 mRNA | CTD | PMID:22538082 |
| piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of MDM2 mRNA | CTD | PMID:15890375 |
| piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:22484513 |
| pirinixic acid | multiple interactions | EXP | | 6480464 | MDM2 protein affects the reaction [pirinixic acid results in increased activity of PPARA protein]; more ... | CTD | PMID:19103650 |
| pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MDM2 mRNA | CTD | PMID:19162173 PMID:15890375 |
| pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MDM2 mRNA | CTD | PMID:15890375 PMID:19162173 |
| potassium dichromate | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] | CTD | PMID:21262251 |
| potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of MDM2 protein | CTD | PMID:21262251 |
| pravastatin | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Pravastatin results in increased phosphorylation of MDM2 protein | CTD | PMID:15625077 |
| pravastatin | increases expression | EXP | | 6480464 | Pravastatin results in increased expression of MDM2 protein | CTD | PMID:15625077 |
| pravastatin | multiple interactions | ISO | RGD:1313299 | 6480464 | Sirolimus inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]; more ... | CTD | PMID:15625077 |
| pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of MDM2 mRNA | CTD | PMID:19162173 |
| quercetin | multiple interactions | ISO | RGD:1313299 | 6480464 | Quercetin results in decreased phosphorylation of and results in decreased expression of MDM2 protein | CTD | PMID:17973296 |
| quercetin | increases expression | ISO | RGD:1313299 | 6480464 | Quercetin results in increased expression of MDM2 mRNA | CTD | PMID:21632981 |
| resveratrol | multiple interactions | ISO | RGD:1313299 | 6480464 | EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]; more ... | CTD | PMID:15542774 |
| resveratrol | multiple interactions | ISO | RGD:1313300 | 6480464 | [resveratrol results in increased phosphorylation of TRP53 protein] inhibits the reaction [TRP53 protein binds to MDM2 protein] | CTD | PMID:11245472 |
| resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 protein | CTD | PMID:11245472 |
| resveratrol | increases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:15280659 PMID:15767336 |
| resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 mRNA | CTD | PMID:16998810 PMID:20878097 |
| resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:16369916 PMID:16081268 |
| resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 protein | CTD | PMID:19846903 |
| resveratrol | multiple interactions | ISO | RGD:1313299 | 6480464 | Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; more ... | CTD | PMID:19846903 |
| resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:16081268 PMID:16369916 |
| resveratrol | affects expression | ISO | RGD:1313300 | 6480464 | resveratrol affects the expression of MDM2 protein | CTD | PMID:16369916 |
| resveratrol | increases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:15767336 |
| resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 mRNA | CTD | PMID:16998810 |
| rifampicin | multiple interactions | ISO | RGD:1313300 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
| ruthenium atom | decreases expression | ISO | RGD:1313299 | 6480464 | Ruthenium results in decreased expression of MDM2 protein | CTD | PMID:17210701 |
| silicon dioxide | increases expression | ISO | RGD:1313300 | 6480464 | Silicon Dioxide results in increased expression of MDM2 mRNA | CTD | PMID:19073995 |
| simvastatin | increases phosphorylation | ISO | RGD:1313299 | 6480464 | Simvastatin results in increased phosphorylation of MDM2 protein | CTD | PMID:15625077 |
| simvastatin | multiple interactions | ISO | RGD:1313299 | 6480464 | Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]] | CTD | PMID:15625077 |
| sirolimus | multiple interactions | ISO | RGD:1313299 | 6480464 | EIF4E protein inhibits the reaction [Sirolimus results in decreased expression of MDM2 protein] | CTD | PMID:19560264 |
| sirolimus | multiple interactions | ISO | RGD:1313299 | 6480464 | Sirolimus promotes the reaction [TP73 protein binds to MDM2 promoter] | CTD | PMID:21245298 |
| sirolimus | decreases expression | ISO | RGD:1313299 | 6480464 | Sirolimus results in decreased expression of MDM2 protein | CTD | PMID:19560264 |
| sirolimus | multiple interactions | ISO | RGD:1313299 | 6480464 | Sirolimus inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein] | CTD | PMID:15625077 |
| sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of MDM2 mRNA | CTD | PMID:22110744 |
| staurosporine | multiple interactions | ISO | RGD:1313299 | 6480464 | Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]] | CTD | PMID:15542774 |
| tamoxifen | affects expression | ISO | RGD:1313300 | 6480464 | Tamoxifen affects the expression of MDM2 mRNA | CTD | PMID:17555576 |
| testosterone | decreases expression | ISO | RGD:1313300 | 6480464 | Testosterone results in decreased expression of MDM2 mRNA | CTD | PMID:20403060 |
| thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MDM2 mRNA | CTD | PMID:18619722 |
| thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MDM2 mRNA | CTD | PMID:18619722 PMID:22659510 |
| titanium dioxide | increases expression | ISO | RGD:1313299 | 6480464 | titanium dioxide results in increased expression of MDM2 mRNA | CTD | PMID:21067279 |
| trans-resveratrol | multiple interactions | ISO | RGD:1313299 | 6480464 | EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]; more ... | CTD | PMID:15542774 |
| trans-resveratrol | multiple interactions | ISO | RGD:1313300 | 6480464 | [resveratrol results in increased phosphorylation of TRP53 protein] inhibits the reaction [TRP53 protein binds to MDM2 protein] | CTD | PMID:11245472 |
| trans-resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 protein | CTD | PMID:11245472 |
| trans-resveratrol | increases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:15280659 PMID:15767336 |
| trans-resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 mRNA | CTD | PMID:16998810 PMID:20878097 |
| trans-resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:16369916 PMID:16081268 |
| trans-resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 protein | CTD | PMID:19846903 |
| trans-resveratrol | multiple interactions | ISO | RGD:1313299 | 6480464 | Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; more ... | CTD | PMID:19846903 |
| trans-resveratrol | increases expression | ISO | RGD:1313300 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:16081268 PMID:16369916 |
| trans-resveratrol | affects expression | ISO | RGD:1313300 | 6480464 | resveratrol affects the expression of MDM2 protein | CTD | PMID:16369916 |
| trans-resveratrol | increases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:15767336 |
| trans-resveratrol | decreases expression | ISO | RGD:1313299 | 6480464 | resveratrol results in decreased expression of MDM2 mRNA | CTD | PMID:16998810 |
| trichloroethene | affects expression | ISO | RGD:1313300 | 6480464 | Trichloroethylene affects the expression of MDM2 mRNA | CTD | PMID:21135412 |
| trichloroethene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
| urethane | multiple interactions | ISO | RGD:1313300 | 6480464 | [Urethane co-treated with Freund's Adjuvant] results in increased expression of MDM2 mRNA | CTD | PMID:12400877 |
| ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | MDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid affects the localization of TP53 protein]; more ... | CTD | PMID:17881359 |
| ursodeoxycholic acid | increases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in increased expression of MDM2 mRNA | CTD | PMID:15885361 |
| ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of MDM2 protein] | CTD | PMID:15222754 PMID:14514686 |
| ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of MDM2 protein] | CTD | PMID:14514686 PMID:15222754 |
| ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | NR3C1 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of MDM2 protein]]; more ... | CTD | PMID:15222754 |
| ursodeoxycholic acid | multiple interactions | ISO | RGD:1313299 | 6480464 | MDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein] | CTD | PMID:20807506 |
| vincristine | decreases expression | ISO | RGD:1313299 | 6480464 | Vincristine results in decreased expression of MDM2 mRNA | CTD | PMID:16001973 |
| wortmannin | multiple interactions | ISO | RGD:1313299 | 6480464 | wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein]; more ... | CTD | PMID:17935137 |
| zidovudine | increases expression | ISO | RGD:1313299 | 6480464 | Zidovudine results in increased expression of MDM2 protein | CTD | PMID:16797627 |
| zinc atom | multiple interactions | ISO | RGD:1313299 | 6480464 | Zinc binds to and results in increased folding of MDM2 protein; more ... | CTD | PMID:16965791 |
| zinc atom | increases ubiquitination | ISO | RGD:1313299 | 6480464 | Zinc results in increased ubiquitination of MDM2 protein | CTD | PMID:16965791 |
| zinc atom | affects expression | ISO | RGD:1313299 | 6480464 | Zinc affects the expression of MDM2 protein | CTD | PMID:16636310 |
| zinc pyrithione | increases expression | ISO | RGD:1313299 | 6480464 | zinc pyrithione results in increased expression of MDM2 mRNA | CTD | PMID:21424779 |
| zinc(0) | multiple interactions | ISO | RGD:1313299 | 6480464 | Zinc binds to and results in increased folding of MDM2 protein; more ... | CTD | PMID:16965791 |
| zinc(0) | affects expression | ISO | RGD:1313299 | 6480464 | Zinc affects the expression of MDM2 protein | CTD | PMID:16636310 |
| zinc(0) | increases ubiquitination | ISO | RGD:1313299 | 6480464 | Zinc results in increased ubiquitination of MDM2 protein | CTD | PMID:16965791 |