Gene: Mdm2 (p53 E3 ubiquitin protein ligase)  Rattus norvegicus

Symbol: Mdm2
Name: p53 E3 ubiquitin protein ligase
Description: ENCODES a protein that exhibits p53 binding; peroxisome proliferator activated receptor binding; ubiquitin-protein ligase activity; INVOLVED IN cellular response to acid; cellular response to alkaloid; cellular response to antibiotic; PARTICIPATES IN altered p53 signaling pathway; p53 signaling pathway; bladder cancer pathway; ASSOCIATED WITH Brain Injuries; Breast Neoplasms; Fetal Growth Retardation; FOUND IN cytosol; nucleus; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: double minute 2; E3 ubiquitin-protein ligase Mdm2; LOC314856; Mdm2 p53 binding protein homolog; Mdm2 p53 binding protein homolog (mouse); mdm2_predicted; Mdm2_predicted; transformed mouse 3T3 cell double minute 2; transformed mouse 3T3 cell double minute 2 (predicted); transformed mouse 3t3 cell double minute 2 homolog (mouse) (predicted); transformed mouse 3T3 cell double minute 2 homolog (mouse) (predicted)
Orthologs: Homo sapiens : MDM2 (MDM2 oncogene, E3 ubiquitin protein ligase)  HGNC
Mus musculus : Mdm2 (transformed mouse 3T3 cell double minute 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map7q22 NCBI
RGSC Genome Assembly v5.0760,719,029 - 60,743,291-NCBI
RGSC Genome Assembly v3.4756,996,694 - 57,020,926-NCBI
Rat Celera Assembly750,062,029 - 50,086,121-NCBI
Genome Assembly 3.1757,018,654 - 57,054,110-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
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RGD Object Information
RGD ID: 1305332
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2013-04-23
Status: ACTIVE