Gene: Mdm2 (MDM2 proto-oncogene) Rattus norvegicus
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Symbol: Mdm2
Name: MDM2 proto-oncogene
Description: ENCODES a protein that exhibits p53 binding; peroxisome proliferator activated receptor binding; ubiquitin-protein transferase activity; INVOLVED IN cellular response to alkaloid; cellular response to antibiotic; cellular response to estrogen stimulus; PARTICIPATES IN altered p53 signaling pathway; p53 signaling pathway; bladder cancer pathway; ASSOCIATED WITH Brain Injuries; breast cancer; breast carcinoma; FOUND IN cytosol; nucleus; plasma membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: double minute 2; E3 ubiquitin-protein ligase Mdm2; LOC314856; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; Mdm2 p53 binding protein homolog (mouse); MDM2 proto-oncogene, E3 ubiquitin protein ligase; p53 E3 ubiquitin protein ligase; transformed mouse 3T3 cell double minute 2; transformed mouse 3T3 cell double minute 2 homolog (mouse)
Orthologs:
Homo sapiens (human) : MDM2 (MDM2 proto-oncogene)  HGNC
Mus musculus (house mouse) : Mdm2 (transformed mouse 3T3 cell double minute 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Mdm2 (MDM2 proto-oncogene)
Pan paniscus (bonobo/pygmy chimpanzee) : MDM2 (MDM2 proto-oncogene)
Canis lupus familiaris (dog) : MDM2 (MDM2 proto-oncogene)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdm2 (MDM2 proto-oncogene)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0760,719,060 - 60,743,618 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0760,719,023 - 60,743,581 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4756,996,694 - 57,020,926 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1757,018,654 - 57,054,110 (-)NCBI
Celera750,062,029 - 50,086,121 (-)NCBI
Cytogenetic Map7q22NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mdm2
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RGD Object Information
RGD ID: 1305332
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-05-09
Status: ACTIVE