Gene: Idh1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic) Rattus norvegicus
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Symbol: Idh1
Name: isocitrate dehydrogenase (NADP(+)) 1, cytosolic
Description: ENCODES a protein that exhibits isocitrate dehydrogenase (NADP+) activity; NADP binding; (R)-2-hydroxyglutarate dehydrogenase activity (ortholog); INVOLVED IN female gonad development; isocitrate metabolic process; response to organic cyclic compound; PARTICIPATES IN citric acid cycle pathway; glutathione metabolic pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute promyelocytic leukemia (ortholog); Adenocarcinoma of Lung (ortholog); FOUND IN peroxisome; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytosolic NADP-isocitrate dehydrogenase; IDH; IDP; isocitrate dehydrogenase 1; isocitrate dehydrogenase 1 (NADP+); isocitrate dehydrogenase 1 (NADP+), soluble; isocitrate dehydrogenase 1 soluble; isocitrate dehydrogenase 1, soluble; isocitrate dehydrogenase [NADP] cytoplasmic; NADP(+)-specific ICDH; oxalosuccinate decarboxylase
Orthologs:
Homo sapiens (human) : IDH1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic)  HGNC  AGR
Mus musculus (house mouse) : Idh1 (isocitrate dehydrogenase 1 (NADP+), soluble)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Idh1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic)
Pan paniscus (bonobo/pygmy chimpanzee) : IDH1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic)
Canis lupus familiaris (dog) : IDH1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Idh1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0971,882,108 - 71,911,645 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0970,660,443 - 70,689,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4963,769,401 - 63,790,622 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1963,916,382 - 63,937,604 (-)NCBI
Celera963,929,810 - 63,951,008 (-)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Idh1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2862
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE