Gene: Erbb4 (erb-b2 receptor tyrosine kinase 4) Rattus norvegicus
Symbol: Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Description: ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN mammary gland development; negative regulation of muscle cell apoptotic process; odontogenesis; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; calcium/calcium-mediated signaling pathway; endocytosis pathway; ASSOCIATED WITH Diabetic Cardiomyopathies; Heart Failure; Median Neuropathy; FOUND IN caveola; cytoplasm; membrane raft; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; haloperidol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-erbB-4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene 4
Orthologs:
Allele / Splice: Erbb4Tn(sb-T2/Bart3)2.208Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0975,021,790 - 76,178,936 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0974,804,287 - 75,310,350 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4966,843,898 - 67,967,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1966,990,879 - 68,114,952 (-)NCBI
Celera967,006,553 - 68,064,842 (-)NCBI
Cytogenetic Map9q32NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Erbb4
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 620486
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-05-31
Status: ACTIVE