Gene: Tbx3 (T-box 3)
Rattus norvegicus
Symbol:
Tbx3
Name:
T-box 3
Description:
ENCODES a protein that exhibits RNA polymerase II activating transcription factor binding (ortholog); RNA polymerase II transcription factor binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; anterior/posterior axis specification, embryo (ortholog); ASSOCIATED WITH Myocardial Infarction; Abnormalities, Multiple (ortholog); Ovarian Neoplasms (ortholog); FOUND IN nucleus (ortholog); transcription factor complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; cefaloridine
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
T-box 3; T-box 3 (ulnar mammary syndrome); T-box protein 3; T-box transcription factor TBX3
Orthologs:
Homo sapiens : TBX3
(T-box 3)
HGNC
Mus musculus : Tbx3
(T-box 3)
MGI
Latest Assembly:
RGSC Genome Assembly v3.4
Position:
Map Chr Position Strand Source Rat Cytogenetic Map 12 q16 NCBI RGSC Genome Assembly v5.0 12 44,328,562 - 44,339,738 - NCBI RGSC Genome Assembly v3.4 12 38,155,494 - 38,166,670 - NCBI Rat Celera Assembly 12 38,555,497 - 38,566,664 - NCBI Genome Assembly 3.1 12 38,018,881 - 38,030,058 - NCBI
Model
Gene-Chemical Interaction Annotations
(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1345948 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TBX3 mRNA CTD PMID:22079256 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of TBX3 mRNA CTD PMID:17557909 17beta-estradiol affects expression ISO RGD:1345948 6480464 Estradiol affects the expression of TBX3 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin results in increased expression of TBX3 mRNA CTD PMID:20106945 PMID:16697128 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1557562 6480464 Tetrachlorodibenzodioxin affects the expression of TBX3 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin results in increased expression of TBX3 mRNA CTD PMID:16697128 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin results in increased expression of TBX3 mRNA CTD PMID:16697128 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin affects the expression of TBX3 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin results in increased expression of TBX3 mRNA CTD PMID:16697128 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345948 6480464 Tetrachlorodibenzodioxin results in increased expression of TBX3 mRNA CTD PMID:19692669 more ... 2,4-dinitrotoluene affects expression EXP 6480464 2,4-dinitrotoluene affects the expression of TBX3 mRNA CTD PMID:21346803 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:1345948 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TBX3 mRNA CTD PMID:19692669 4,4'-diaminodiphenylmethane decreases expression ISO RGD:1557562 6480464 4,4'-diaminodiphenylmethane results in decreased expression of TBX3 mRNA CTD PMID:18648102 5-aza-2'-deoxycytidine increases expression ISO RGD:1345948 6480464 decitabine results in increased expression of TBX3 mRNA CTD PMID:16367923 afimoxifene multiple interactions ISO RGD:1345948 6480464 PD 173074 inhibits the reaction [4-hydroxytamoxifen results in increased expression of TBX3 protein]; more ... CTD PMID:21098263 all-trans-retinoic acid increases expression ISO RGD:1557562 6480464 Tretinoin results in increased expression of TBX3 mRNA CTD PMID:16604517 all-trans-retinoic acid increases expression ISO RGD:1345948 6480464 Tretinoin results in increased expression of TBX3 mRNA CTD PMID:21934132 benzo[a]pyrene increases expression ISO RGD:1345948 6480464 Benzo(a)pyrene results in increased expression of TBX3 mRNA CTD PMID:21802500 PMID:22316170 benzo[a]pyrene decreases expression ISO RGD:1557562 6480464 Benzo(a)pyrene results in decreased expression of TBX3 mRNA CTD PMID:22228805 bisphenol A increases expression ISO RGD:1345948 6480464 bisphenol A results in increased expression of TBX3 mRNA CTD PMID:20678512 carmustine affects response to substance ISO RGD:1345948 6480464 TBX3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 cefaloridine decreases expression EXP 6480464 Cephaloridine results in decreased expression of TBX3 mRNA CTD PMID:18500788 ciguatoxin CTX1B affects expression ISO RGD:1557562 6480464 Ciguatoxins affects the expression of TBX3 mRNA CTD PMID:18353800 copper(2+) sulfate decreases expression ISO RGD:1345948 6480464 Copper Sulfate results in decreased expression of TBX3 mRNA CTD PMID:19549813 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of TBX3 mRNA] CTD PMID:20032058 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of TBX3 mRNA CTD PMID:20032058 disodium selenite decreases expression ISO RGD:1557562 6480464 Sodium Selenite results in decreased expression of TBX3 mRNA CTD PMID:23274088 diuron increases expression EXP 6480464 Diuron results in increased expression of TBX3 mRNA CTD PMID:21551480 fonofos increases methylation ISO RGD:1345948 6480464 Fonofos results in increased methylation of TBX3 promoter CTD PMID:22847954 hydrogen peroxide affects expression ISO RGD:1345948 6480464 Hydrogen Peroxide affects the expression of TBX3 mRNA CTD PMID:20044591 methylmercury chloride affects expression ISO RGD:1557562 6480464 methylmercuric chloride affects the expression of TBX3 mRNA CTD PMID:21613230 parathion increases methylation ISO RGD:1345948 6480464 Parathion results in increased methylation of TBX3 promoter CTD PMID:22847954 phenobarbital multiple interactions ISO RGD:1557562 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of TBX3 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:1557562 6480464 Phenobarbital affects the expression of TBX3 mRNA CTD PMID:23091169 phenobarbital decreases expression ISO RGD:1557562 6480464 Phenobarbital results in decreased expression of TBX3 mRNA CTD PMID:19482888 propiconazole decreases expression ISO RGD:1557562 6480464 propiconazole results in decreased expression of TBX3 mRNA CTD PMID:21278054 quercetin increases expression ISO RGD:1345948 6480464 Quercetin results in increased expression of TBX3 mRNA CTD PMID:21632981 rosiglitazone increases expression EXP 6480464 rosiglitazone results in increased expression of TBX3 mRNA CTD PMID:21515302 sulindac increases expression ISO RGD:1345948 6480464 Sulindac results in increased expression of TBX3 mRNA CTD PMID:11906190 temozolomide affects response to substance ISO RGD:1345948 6480464 TBX3 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 terbufos increases methylation ISO RGD:1345948 6480464 terbufos results in increased methylation of TBX3 promoter CTD PMID:22847954 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of TBX3 mRNA] CTD PMID:20032058 troglitazone increases expression ISO RGD:1557562 6480464 troglitazone results in increased expression of TBX3 mRNA CTD PMID:17569031 valproic acid decreases expression ISO RGD:1557562 6480464 Valproic Acid results in decreased expression of TBX3 mRNA CTD PMID:22045034 zinc atom multiple interactions ISO RGD:1345948 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of TBX3 mRNA CTD PMID:18593933 zinc sulfate decreases expression ISO RGD:1345948 6480464 Zinc Sulfate results in decreased expression of TBX3 mRNA CTD PMID:16330358 zinc(0) multiple interactions ISO RGD:1345948 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of TBX3 mRNA CTD PMID:18593933
Biological Process
anterior/posterior axis specification, embryo ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 anterior/posterior axis specification, embryo ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 atrioventricular bundle cell differentiation ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3847383 PMID:18467625 atrioventricular bundle cell differentiation IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 blood vessel development ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:2653226 PMID:12668638 blood vessel development IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 branching involved in mammary gland duct morphogenesis ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:3608166 PMID:16222716 branching involved in mammary gland duct morphogenesis IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 cardiac muscle cell differentiation ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:3783941 PMID:17234970 cardiac muscle cell fate commitment ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3847383 PMID:18467625 cardiac muscle cell fate commitment IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 cell aging ISO RGD:1557562 1624291 MGI:MGI:2159048|PMID:11748239 RGD MGI:MGI:2159048 PMID:11748239 cell aging ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 cell aging ISO RGD:1345948 1624291 PMID:11748239 RGD PMID:11748239 cell aging ISO RGD:1345948 1624291 PMID:11689487 RGD PMID:11689487 cellular senescence ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 cellular senescence ISO RGD:1345948 1624291 PMID:22002537 RGD PMID:22002537 embryonic digit morphogenesis ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 embryonic digit morphogenesis ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 embryonic digit morphogenesis ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 embryonic forelimb morphogenesis ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 embryonic forelimb morphogenesis ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 female genitalia development ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 female genitalia development ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 follicle-stimulating hormone secretion ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 follicle-stimulating hormone secretion ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 forelimb morphogenesis ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 heart looping ISO RGD:1557562 1624291 MGI:MGI:3769504 RGD MGI:MGI:3769096 PMID:17460765 heart looping IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 heart looping ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:4412356 PMID:18723448 heart morphogenesis ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 in utero embryonic development ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 in utero embryonic development IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 limb morphogenesis ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:2653226 PMID:12668638 limbic system development ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 limbic system development IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 luteinizing hormone secretion ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 luteinizing hormone secretion ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 male genitalia development ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 male genitalia development ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 mammary gland development ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:2653226 PMID:12668638 mammary gland development ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 mammary gland development ISO RGD:1345948 1624291 PMID:12116211 RGD PMID:12116211 mammary gland development ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 mammary gland development ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:3608166 PMID:16222716 mammary placode formation ISO RGD:1557562 1624291 MGI:MGI:98494 RGD MGI:MGI:3608166 PMID:16222716 mammary placode formation IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 mammary placode formation ISO RGD:1557562 1624291 MGI:MGI:3695659|PMID:17071745 RGD MGI:MGI:3695659 PMID:17071745 mesoderm morphogenesis ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 mesoderm morphogenesis ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 negative regulation of apoptotic process IMP 1601420 RGD negative regulation of apoptotic process ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 negative regulation of apoptotic process ISO RGD:1345948 1624291 PMID:12032820 RGD PMID:12032820 negative regulation of epithelial cell differentiation ISO RGD:1557562 1624291 MGI:MGI:3769504 RGD MGI:MGI:3788969 PMID:18356246 negative regulation of epithelial cell differentiation IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 negative regulation of myoblast differentiation ISO RGD:1345948 1624291 PMID:12032820 RGD PMID:12032820 negative regulation of myoblast differentiation ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 negative regulation of transcription from RNA polymerase II promoter IMP PMID:18285513 MGI PMID:18285513 negative regulation of transcription, DNA-dependent ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 negative regulation of transcription, DNA-dependent ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 negative regulation of transcription, DNA-dependent ISO RGD:1345948 1624291 PMID:11689487 RGD PMID:11689487 negative regulation of transcription, DNA-dependent ISO RGD:1345948 1624291 PMID:10468588 RGD PMID:10468588 negative regulation of transcription, DNA-dependent ISO RGD:1557562 1624291 MGI:MGI:2159048|PMID:11748239 RGD MGI:MGI:2159048 PMID:11748239 organ morphogenesis ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 outflow tract morphogenesis ISO RGD:1557562 1624291 MGI:MGI:2655214 RGD MGI:MGI:4412356 PMID:18723448 outflow tract morphogenesis IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 palate development ISO RGD:1557562 1624291 MGI:MGI:98494 RGD MGI:MGI:4411938 PMID:19769959 palate development IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 positive regulation of cell cycle ISO RGD:1345948 1624291 PMID:12032820 RGD PMID:12032820 positive regulation of cell cycle ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 positive regulation of cell proliferation ISO RGD:1345948 1624291 PMID:11689487 RGD PMID:11689487 positive regulation of cell proliferation ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 positive regulation of cell proliferation ISO RGD:1345948 1624291 PMID:12032820 RGD PMID:12032820 positive regulation of cell proliferation ISO RGD:1345948 1624291 PMID:11748239 RGD PMID:11748239 positive regulation of stem cell proliferation ISO RGD:1557562 1624291 MGI:MGI:3769504 RGD MGI:MGI:3788969 PMID:18356246 positive regulation of stem cell proliferation IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 positive regulation of transcription, DNA-dependent ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3709665 PMID:17473172 positive regulation of transcription, DNA-dependent IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 regulation of cell proliferation ISO RGD:1557562 1624291 MGI:MGI:3769504 RGD MGI:MGI:3769096 PMID:17460765 sinoatrial node cell development ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:4366226 PMID:19096026 sinoatrial node cell development IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 skeletal system development ISO RGD:1345948 1624291 PMID:9207801 RGD PMID:9207801 skeletal system development ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 specification of organ position ISO RGD:1557562 1624291 MGI:MGI:3695659|PMID:17071745 RGD MGI:MGI:3695659 PMID:17071745 specification of organ position IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 stem cell maintenance ISO RGD:1557562 1624291 MGI:MGI:3769504 RGD MGI:MGI:3788969 PMID:18356246 stem cell maintenance IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019 transcription, DNA-dependent IEA UniProtKB-KW:KW-0804 1600115 GO_REF:0000037 UniProtKB GO_REF:0000037 ventricular septum morphogenesis ISO RGD:1557562 1624291 MGI:MGI:3710254 RGD MGI:MGI:3847383 PMID:18467625 ventricular septum morphogenesis IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019
Cellular Component
cellular_component ND 1598407 06/2011: no relevant rat data RGD nucleus ISO RGD:1557562 1624291 MGI:MGI:3801344|PMID:18534921 RGD MGI:MGI:3801344 PMID:18534921 nucleus ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 nucleus ISO RGD:1345948 1624291 PMID:11689487 RGD PMID:11689487 nucleus ISO RGD:1557562 1624291 MGI:MGI:4440736|PMID:19765559 RGD MGI:MGI:4440736 PMID:19765559 nucleus ISO RGD:1557562 1624291 MGI:MGI:4412356|PMID:18723448 RGD MGI:MGI:4412356 PMID:18723448 transcription factor complex ISO RGD:1557562 1624291 UniProtKB:Q5SSP7 RGD MGI:MGI:4461870 PMID:18285513
Molecular Function
molecular_function ND 1598407 06/2011: no relevant rat data RGD protein binding ISO RGD:1345948 1624291 UniProtKB:P29590-4 RGD PMID:22002537 RNA polymerase II activating transcription factor binding ISO RGD:1557562 1624291 UniProtKB:Q9WUI0 RGD MGI:MGI:5448510 PMID:22164283 RNA polymerase II transcription factor binding ISO RGD:1557562 1624291 UniProtKB:Q02591 RGD MGI:MGI:5448510 PMID:22164283 sequence-specific DNA binding ISO RGD:1345948 1624291 PMID:11689487 RGD PMID:11689487 sequence-specific DNA binding ISS UniProtKB:O15119 1600115 GO_REF:0000024 UniProtKB GO_REF:0000024 sequence-specific DNA binding transcription factor activity ISO RGD:1557562 1624291 MGI:MGI:3709665|PMID:17473172 RGD MGI:MGI:3709665 PMID:17473172 sequence-specific DNA binding transcription factor activity IEA Ensembl:ENSMUSP00000018748 1600115 GO_REF:0000019 ENSEMBL GO_REF:0000019
2303575 Insul14 Insulin level QTL 14 4 Insulin level 12 1 43562201 Rat 737979 Pia22 Pristane induced arthritis QTL 22 53.1 Joint/bone inflammation arthritis severity 12 530865 45530865 Rat 61416 Pia4 Pristane induced arthritis QTL 4 8.4 Joint/bone inflammation number of affected paws 12 568621 45568621 Rat 634351 Apr5 Acute phase response QTL 5 6.7 IL-6 level pristane induced 12 568621 45568621 Rat 2302042 Pia38 Pristane induced arthritis QTL 38 3.5 .001 Joint/bone inflammation pristane induced 12 568621 45568621 Rat 634350 Apr4 Acute phase response QTL 4 6 Alpha1 acid glycoprotein level pristane induced 12 2248421 46782294 Rat 1549829 Scl48 Serum cholesterol level QTL 48 5 Lipid level baseline serum cholesterol 12 10716230 46782294 Rat 1331761 Bp218 Blood pressure QTL 218 2.973 Blood pressure mean arterial 12 11416955 46782294 Rat 2293699 Bss49 Bone structure and strength QTL 49 5.61 .0001 Bone structure 12 11612769 46782294 Rat 2300186 Bmd59 Bone mineral density QTL 59 7.1 .0001 Bone mineral density 12 11612769 46782294 Rat 61404 Bw120 Body weight QTL 120 5.1 Body weight body mass index 12 12770194 42387195 Rat 1641928 Alcrsp5 Alcohol response QTL 5 Alcohol response loss of righting reflex 12 13948769 46782294 Rat 2303569 Gluco44 Glucose level QTL 44 2 Glucose level fasting 12 13948769 46782294 Rat 2302060 Pia37 Pristane induced arthritis QTL 37 6.1 .001 Joint/bone inflammation pristane induced 12 14334630 46782294 Rat 1549902 Bp269 Blood pressure QTL 269 Blood pressure diastolic, daytime 12 14356765 46782294 Rat 1549912 Bp268 Blood pressure QTL 268 Blood pressure diastolic, daytime 10 14356765 46782294 Rat 631543 Bp83 Blood pressure QTL 83 5.8 Blood pressure systolic 12 16535858 39626712 Rat 70213 Niddm27 Non-insulin dependent diabetes mellitus QTL 27 3.72 Glucose level fasting 12 18937438 39323046 Rat 631560 Apr1 Acute phase response QTL 1 6.1 Alpha1 acid glycoprotein level pristane induced 12 20418353 46782294 Rat 737822 Alc10 Alcohol consumption QTL 10 2.2 Consumption level alcohol preference 12 20932559 41447890 Rat 5684888 Pia42 Pristane induced arthritis QTL 42 Joint/bone inflammation pristane induced 12 20932559 43863270 Rat 1556747 Calcic1 Intracellular calcium level QTL 1 3.6 Intracellular calcium level thrombin-stimulated 12 29130180 42387195 Rat 1600386 Calcic2 Intracellular calcium level QTL 2 .001 Intracellular calcium level thrombin-stimulated 12 29130180 42387195 Rat 1300175 Cm5 Cardiac mass QTL 5 3.78 Cardiac mass salt-loaded left ventricle 12 29130180 46043557 Rat 1331787 Rf41 Renal function QTL 41 2.998 Renal function renal blood flow 12 29130304 41447755 Rat 631829 Alc6 Alcohol consumption QTL 6 4.7 Consumption level alcohol preference 12 29675888 39018219 Rat 1300162 Bp188 Blood pressure QTL 188 3.19 Blood pressure salt-loaded systolic 12 33216127 46043557 Rat