Gene: Dpyd (dihydropyrimidine dehydrogenase) Rattus norvegicus
Symbol: Dpyd
Name: dihydropyrimidine dehydrogenase
Description: ENCODES a protein that exhibits dihydropyrimidine dehydrogenase (NADP+) activity; NADP binding; protein homodimerization activity; INVOLVED IN circadian rhythm; pyrimidine nucleobase catabolic process; response to drug; PARTICIPATES IN pyrimidine metabolic pathway; beta-alanine metabolic pathway; pantothenic acid metabolic pathway; ASSOCIATED WITH Liver Diseases; Dihydropyrimidine Dehydrogenase Deficiency (ortholog); Gallbladder Neoplasms (ortholog); FOUND IN cytosol; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
Also known as: DHPDHase; dihydropyrimidine dehydrogenase [NADP(+)]; dihydropyrimidine dehydrogenase [NADP+]; dihydrothymine dehydrogenase; dihydrouracil dehydrogenase; DPD
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.02221,823,692 - 222,694,627+NCBI
Rat Cytogenetic Map2q41 NCBI
RGSC Genome Assembly v5.02240,072,322 - 240,744,042+NCBI
RGSC Genome Assembly v5.02239,874,415 - 240,000,215+NCBI
RGSC Genome Assembly v3.42214,931,901 - 215,818,809+NCBI
Rat Celera Assembly2199,080,477 - 199,932,183+NCBI
Genome Assembly 3.12214,894,962 - 215,781,871+NCBI
Launch Genome Browser (GBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dpyd
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 621218
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE