Gene: Dpyd (dihydropyrimidine dehydrogenase) Rattus norvegicus
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Symbol: Dpyd
Name: dihydropyrimidine dehydrogenase
Description: ENCODES a protein that exhibits dihydropyrimidine dehydrogenase (NADP+) activity; dihydrouracil dehydrogenase (NAD+) activity; FAD binding; INVOLVED IN aging; circadian rhythm; pyrimidine nucleobase catabolic process; PARTICIPATES IN pyrimidine metabolic pathway; beta-alanine metabolic pathway; beta-ureidopropionase deficiency pathway; ASSOCIATED WITH Colorectal Neoplasms; hemangioma of liver; hepatic infarction; FOUND IN cytosol; cytoplasm (ortholog); INTERACTS WITH 1-benzylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DHPDHase; dihydropyrimidine dehydrogenase [NADP(+)]; dihydropyrimidine dehydrogenase [NADP+]; dihydrothymine dehydrogenase; dihydrouracil dehydrogenase; DPD
Orthologs:
Homo sapiens (human) : DPYD (dihydropyrimidine dehydrogenase)  HGNC  AGR
Mus musculus (house mouse) : Dpyd (dihydropyrimidine dehydrogenase)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Dpyd (dihydropyrimidine dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : DPYD (dihydropyrimidine dehydrogenase)
Canis lupus familiaris (dog) : DPYD (dihydropyrimidine dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpyd (dihydropyrimidine dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02221,823,692 - 222,694,627 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02240,072,322 - 240,744,042 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.02239,874,415 - 240,000,215 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42214,931,901 - 215,818,809 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12214,894,962 - 215,781,871 (+)NCBI
Celera2199,080,477 - 199,932,183 (+)NCBI
Cytogenetic Map2q41NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dpyd
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 621218
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE