Gene: Tek (TEK tyrosine kinase, endothelial)  Rattus norvegicus

Symbol: Tek
Name: TEK tyrosine kinase, endothelial
Description: ENCODES a protein that exhibits growth factor binding; protein tyrosine kinase activity (ortholog); receptor activity (ortholog); INVOLVED IN angiogenesis; endochondral ossification; intracellular signal transduction; PARTICIPATES IN angiopoietin signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH Acute Kidney Injury; Brain Ischemia; Carcinoma, Hepatocellular; FOUND IN actin filament (ortholog); apical plasma membrane (ortholog); basal plasma membrane (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiopoietin-1 receptor; endothelial-specific receptor tyrosine kinase; TEK tyrosine kinase, endothelial; Tie-2; Tie2; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
Orthologs: Homo sapiens : TEK (TEK tyrosine kinase, endothelial)  HGNC
Mus musculus : Tek (endothelial-specific receptor tyrosine kinase)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q33 NCBI
RGSC Genome Assembly v5.05117,672,484 - 117,799,345+NCBI
RGSC Genome Assembly v3.45115,047,195 - 115,196,172+NCBI
Rat Celera Assembly5108,234,353 - 108,354,536+NCBI
Genome Assembly 3.15115,171,316 - 115,174,864+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tek
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 620980
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2013-04-30
Status: ACTIVE